Year |
Citation |
Score |
2020 |
Kabitzke P, Morales D, He D, Cox K, Sutphen J, Thiede L, Sabath E, Hanania T, Biemans B, Brunner D. Mouse Model Systems of Autism Spectrum Disorder: Replicability and Informatics Signature. Genes, Brain, and Behavior. e12676. PMID 32445272 DOI: 10.1111/Gbb.12676 |
0.32 |
|
2019 |
Kaufmann WE, Sprouse J, Rebowe N, Hanania T, Klamer D, Missling CU. ANAVEX®2-73 (blarcamesine), a Sigma-1 receptor agonist, ameliorates neurologic impairments in a mouse model of Rett syndrome. Pharmacology, Biochemistry, and Behavior. 187: 172796. PMID 31704481 DOI: 10.1016/j.pbb.2019.172796 |
0.366 |
|
2019 |
Dedic N, Jones PG, Hopkins SC, Lew R, Shao L, Campbell JE, Spear KL, Large TH, Campbell UC, Hanania T, Leahy E, Koblan K. SEP-363856, A NOVEL PSYCHOTROPIC AGENT WITH A UNIQUE, NON-D2 RECEPTOR MECHANISM OF ACTION. The Journal of Pharmacology and Experimental Therapeutics. PMID 31371483 DOI: 10.1124/jpet.119.260281 |
0.38 |
|
2017 |
Kabitzke P, Brunner D, He D, Fazio PA, Cox K, Sutphen J, Thiede L, Sabath E, Hanania T, Alexandrov V, Rasmusson R, Spooren W, Ghosh A, Feliciano P, Biemans B, et al. Comprehensive Analysis of Two Shank3 and the Cacna1c Mouse Models of Autism Spectrum Disorder. Genes, Brain, and Behavior. PMID 28753255 DOI: 10.1111/Gbb.12405 |
0.324 |
|
2016 |
Shao L, Campbell UC, Fang QK, Powell NA, Campbell JE, Jones PG, Hanania T, Alexandrov V, Morganstern I, Sabath E, Zhong HM, Large TH, Spear KL. In vivo phenotypic drug discovery: Applying a behavioral assay to the discovery and optimization of novel antipsychotic agents Medchemcomm. 7: 1093-1101. DOI: 10.1039/c6md00128a |
0.323 |
|
2015 |
Brunner D, Kabitzke P, He D, Cox K, Thiede L, Hanania T, Sabath E, Alexandrov V, Saxe M, Peles E, Mills A, Spooren W, Ghosh A, Feliciano P, Benedetti M, et al. Comprehensive Analysis of the 16p11.2 Deletion and Null Cntnap2 Mouse Models of Autism Spectrum Disorder. Plos One. 10: e0134572. PMID 26273832 DOI: 10.1371/Journal.Pone.0134572 |
0.339 |
|
2015 |
Henry MA, Fairchild DD, Patil MJ, Hanania T, Hain HS, Davis SF, Malekiani SA, Hu A, Sucholeiki R, Nix D, Sucholeiki I. Effect of a Novel, Orally Active Matrix Metalloproteinase-2 and -9 Inhibitor in Spinal and Trigeminal Rat Models of Neuropathic Pain. Journal of Oral & Facial Pain and Headache. 29: 286-96. PMID 26244437 DOI: 10.11607/Ofph.1350 |
0.306 |
|
2015 |
Chang Q, Hanania T, Mash DC, Maillet EL. Noribogaine reduces nicotine self-administration in rats. Journal of Psychopharmacology (Oxford, England). 29: 704-11. PMID 25995321 DOI: 10.1177/0269881115584461 |
0.337 |
|
2015 |
Alexandrov V, Brunner D, Hanania T, Leahy E. Reprint of: Highthroughtput analysis of behavior for drug discovery. European Journal of Pharmacology. 753: 127-34. PMID 25744878 DOI: 10.1016/J.Ejphar.2015.02.037 |
0.32 |
|
2015 |
Alexandrov V, Brunner D, Hanania T, Leahy E. High-throughput analysis of behavior for drug discovery. European Journal of Pharmacology. 750: 82-9. PMID 25592319 DOI: 10.1016/J.Ejphar.2014.11.047 |
0.321 |
|
2014 |
Yu LF, Brek Eaton J, Zhang HK, Sabath E, Hanania T, Li GN, van Breemen RB, Whiteaker P, Liu Q, Wu J, Chang YC, Lukas RJ, Brunner D, Kozikowski AP. The potent and selective α4β2*/α6*-nicotinic acetylcholine receptor partial agonist 2-[5-[5-((S)Azetidin-2-ylmethoxy)-3-pyridinyl]-3-isoxazolyl]ethanol demonstrates antidepressive-like behavior in animal models and a favorable ADME-tox profile. Pharmacology Research & Perspectives. 2: e00026. PMID 25505580 DOI: 10.1002/Prp2.26 |
0.41 |
|
2013 |
Hanson JE, La H, Plise E, Chen YH, Ding X, Hanania T, Sabath EV, Alexandrov V, Brunner D, Leahy E, Steiner P, Liu L, Scearce-Levie K, Zhou Q. SAHA enhances synaptic function and plasticity in vitro but has limited brain availability in vivo and does not impact cognition. Plos One. 8: e69964. PMID 23922875 DOI: 10.1371/journal.pone.0069964 |
0.319 |
|
2013 |
Zhang HK, Yu LF, Eaton JB, Whiteaker P, Onajole OK, Hanania T, Brunner D, Lukas RJ, Kozikowski AP. Chemistry, pharmacology, and behavioral studies identify chiral cyclopropanes as selective α4β2-nicotinic acetylcholine receptor partial agonists exhibiting an antidepressant profile. Part II. Journal of Medicinal Chemistry. 56: 5495-504. PMID 23734673 DOI: 10.1021/Jm400510U |
0.39 |
|
2013 |
Gunosewoyo H, Midzak A, Gaisina IN, Sabath EV, Fedolak A, Hanania T, Brunner D, Papadopoulos V, Kozikowski AP. Characterization of maleimide-based glycogen synthase kinase-3 (GSK-3) inhibitors as stimulators of steroidogenesis. Journal of Medicinal Chemistry. 56: 5115-29. PMID 23725591 DOI: 10.1021/Jm400511S |
0.378 |
|
2012 |
Yu LF, Eaton JB, Fedolak A, Zhang HK, Hanania T, Brunner D, Lukas RJ, Kozikowski AP. Discovery of highly potent and selective α4β2-nicotinic acetylcholine receptor (nAChR) partial agonists containing an isoxazolylpyridine ether scaffold that demonstrate antidepressant-like activity. Part II. Journal of Medicinal Chemistry. 55: 9998-10009. PMID 23092294 DOI: 10.1021/Jm301177J |
0.371 |
|
2012 |
Zhang HK, Eaton JB, Yu LF, Nys M, Mazzolari A, van Elk R, Smit AB, Alexandrov V, Hanania T, Sabath E, Fedolak A, Brunner D, Lukas RJ, Vistoli G, Ulens C, et al. Insights into the structural determinants required for high-affinity binding of chiral cyclopropane-containing ligands to α4β2-nicotinic acetylcholine receptors: an integrated approach to behaviorally active nicotinic ligands. Journal of Medicinal Chemistry. 55: 8028-37. PMID 22928944 DOI: 10.1021/Jm3008739 |
0.339 |
|
2012 |
Yu LF, Tückmantel W, Eaton JB, Caldarone B, Fedolak A, Hanania T, Brunner D, Lukas RJ, Kozikowski AP. Identification of novel α4β2-nicotinic acetylcholine receptor (nAChR) agonists based on an isoxazole ether scaffold that demonstrate antidepressant-like activity. Journal of Medicinal Chemistry. 55: 812-23. PMID 22148173 DOI: 10.1021/Jm201301H |
0.409 |
|
2012 |
Paterson NE, Wetzler C, Hackett A, Hanania T. Impulsive action and impulsive choice are mediated by distinct neuropharmacological substrates in rat. The International Journal of Neuropsychopharmacology / Official Scientific Journal of the Collegium Internationale Neuropsychopharmacologicum (Cinp). 15: 1473-87. PMID 22094071 DOI: 10.1017/S1461145711001635 |
0.377 |
|
2011 |
Roberds SL, Filippov I, Alexandrov V, Hanania T, Brunner D. Rapid, computer vision-enabled murine screening system identifies neuropharmacological potential of two new mechanisms. Frontiers in Neuroscience. 5: 103. PMID 21927596 DOI: 10.3389/Fnins.2011.00103 |
0.386 |
|
2011 |
Vinkers CH, Olivier B, Hanania T, Min W, Schreiber R, Hopkins SC, Campbell U, Paterson N. Discriminative stimulus properties of GABAA receptor positive allosteric modulators TPA023, ocinaplon and NG2-73 in rats trained to discriminate chlordiazepoxide or zolpidem. European Journal of Pharmacology. 668: 190-3. PMID 21762686 DOI: 10.1016/J.Ejphar.2011.06.054 |
0.383 |
|
2011 |
Caldarone BJ, Wang D, Paterson NE, Manzano M, Fedolak A, Cavino K, Kwan M, Hanania T, Chellappan SK, Kozikowski AP, Olivier B, Picciotto MR, Ghavami A. Dissociation between duration of action in the forced swim test in mice and nicotinic acetylcholine receptor occupancy with sazetidine, varenicline, and 5-I-A85380. Psychopharmacology. 217: 199-210. PMID 21487659 DOI: 10.1007/S00213-011-2271-Y |
0.404 |
|
2011 |
Paterson NE, Ricciardi J, Wetzler C, Hanania T. Sub-optimal performance in the 5-choice serial reaction time task in rats was sensitive to methylphenidate, atomoxetine and d-amphetamine, but unaffected by the COMT inhibitor tolcapone. Neuroscience Research. 69: 41-50. PMID 20934466 DOI: 10.1016/j.neures.2010.10.001 |
0.327 |
|
2011 |
Paterson NE, Balci F, Campbell U, Olivier BE, Hanania T. The triple reuptake inhibitor DOV216,303 exhibits limited antidepressant-like properties in the differential reinforcement of low-rate 72-second responding assay, likely due to dopamine reuptake inhibition. Journal of Psychopharmacology (Oxford, England). 25: 1357-64. PMID 20305042 DOI: 10.1177/0269881110364272 |
0.345 |
|
2010 |
Paterson NE, Min W, Hackett A, Lowe D, Hanania T, Caldarone B, Ghavami A. The high-affinity nAChR partial agonists varenicline and sazetidine-A exhibit reinforcing properties in rats. Progress in Neuro-Psychopharmacology & Biological Psychiatry. 34: 1455-64. PMID 20708056 DOI: 10.1016/j.pnpbp.2010.07.037 |
0.339 |
|
2010 |
Paterson NE, Fedolak A, Olivier B, Hanania T, Ghavami A, Caldarone B. Psychostimulant-like discriminative stimulus and locomotor sensitization properties of the wake-promoting agent modafinil in rodents. Pharmacology, Biochemistry, and Behavior. 95: 449-56. PMID 20346966 DOI: 10.1016/J.Pbb.2010.03.006 |
0.326 |
|
2010 |
Paterson NE, Iwunze M, Davis SF, Malekiani SA, Hanania T. Comparison of the predictive validity of the mirror chamber and elevated plus maze tests in mice. Journal of Neuroscience Methods. 188: 62-70. PMID 20149823 DOI: 10.1016/j.jneumeth.2010.02.005 |
0.369 |
|
2010 |
Paterson NE, Hanania T. The modified Geller-Seifter test in rats was insensitive to GABAB receptor positive modulation or blockade, or 5-HT1A receptor activation. Behavioural Brain Research. 208: 258-64. PMID 20006648 DOI: 10.1016/j.bbr.2009.12.006 |
0.389 |
|
2009 |
Paterson NE, Malekiani SA, Foreman MM, Olivier B, Hanania T. Pharmacological characterization of harmaline-induced tremor activity in mice. European Journal of Pharmacology. 616: 73-80. PMID 19497322 DOI: 10.1016/J.Ejphar.2009.05.031 |
0.394 |
|
2009 |
Foreman MM, Hanania T, Eller M. Anxiolytic effects of lamotrigine and JZP-4 in the elevated plus maze and in the four plate conflict test. European Journal of Pharmacology. 602: 316-20. PMID 19038245 DOI: 10.1016/j.ejphar.2008.11.013 |
0.313 |
|
2009 |
Hackett A, Caldarone B, Kozikowski AP, Ghavami A, Olivier B, Hanania T, Paterson NE. The nAChR agonist AMOP-H-OH (‘sazetidine-A’) exhibits reinforcing, but not withdrawal-alleviating, properties in rats Biochemical Pharmacology. 78: 919. DOI: 10.1016/J.Bcp.2009.06.079 |
0.308 |
|
2008 |
Breuer ME, Chan JS, Oosting RS, Groenink L, Korte SM, Campbell U, Schreiber R, Hanania T, Snoeren EM, Waldinger M, Olivier B. The triple monoaminergic reuptake inhibitor DOV 216,303 has antidepressant effects in the rat olfactory bulbectomy model and lacks sexual side effects. European Neuropsychopharmacology : the Journal of the European College of Neuropsychopharmacology. 18: 908-16. PMID 18789657 DOI: 10.1016/J.Euroneuro.2008.07.011 |
0.331 |
|
2008 |
Vinkers CH, van Bogaert MJ, Klanker M, Korte SM, Oosting R, Hanania T, Hopkins SC, Olivier B, Groenink L. Translational aspects of pharmacological research into anxiety disorders: the stress-induced hyperthermia (SIH) paradigm. European Journal of Pharmacology. 585: 407-25. PMID 18420191 DOI: 10.1016/J.Ejphar.2008.02.097 |
0.303 |
|
1999 |
Hanania T, Johnson KM. Regulation of NMDA-stimulated [14C]GABA and [3H]acetylcholine release by striatal glutamate and dopamine receptors. Brain Research. 844: 106-17. PMID 10536266 DOI: 10.1016/S0006-8993(99)01869-7 |
0.529 |
|
1999 |
Hanania T, Hillman GR, Johnson KM. Augmentation of locomotor activity by chronic phencyclidine is associated with an increase in striatal NMDA receptor function and an upregulation of the NR1 receptor subunit. Synapse (New York, N.Y.). 31: 229-39. PMID 10029241 DOI: 10.1002/(SICI)1098-2396(19990301)31:3<229::AID-SYN8>3.0.CO;2-3 |
0.38 |
|
1998 |
Hanania T, Johnson KM. Regulation of neurotransmitter release by endogenous nitric oxide in striatal slices. European Journal of Pharmacology. 359: 111-7. PMID 9832380 DOI: 10.1016/S0014-2999(98)00636-0 |
0.334 |
|
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