Gerard Sanacora - Publications

Affiliations: 
Yale University, New Haven, CT 
Area:
Psychiatry

121 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any innacuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2019 Krystal JH, Abdallah CG, Sanacora G, Charney DS, Duman RS. Ketamine: A Paradigm Shift for Depression Research and Treatment. Neuron. 101: 774-778. PMID 30844397 DOI: 10.1016/j.neuron.2019.02.005  0.92
2019 Fava M, Freeman MP, Flynn M, Judge H, Hoeppner BB, Cusin C, Ionescu DF, Mathew SJ, Chang LC, Iosifescu DV, Murrough J, Debattista C, Schatzberg AF, Trivedi MH, Jha MK, ... Sanacora G, et al. Correction: Double-blind, placebo-controlled, dose-ranging trial of intravenous ketamine as adjunctive therapy in treatment-resistant depression (TRD). Molecular Psychiatry. PMID 30617276 DOI: 10.1038/s41380-018-0311-2  0.6
2018 Krystal AD, Pizzagalli DA, Mathew SJ, Sanacora G, Keefe R, Song A, Calabrese J, Goddard A, Goodman W, Lisanby SH, Smoski M, Weiner R, Iosifescu D, Nurnberger J, Szabo S, et al. The first implementation of the NIMH FAST-FAIL approach to psychiatric drug development. Nature Reviews. Drug Discovery. 18: 82-84. PMID 30591715 DOI: 10.1038/nrd.2018.222  0.36
2018 Mathew SJ, Wilkinson ST, Altinay M, Asghar-Ali A, Chang LC, Collins KA, Dale RM, Hu B, Krishnan K, Kellner CH, Malone DA, Murrough JW, Ostroff RB, Sanacora G, Shao M, et al. ELEctroconvulsive therapy (ECT) vs. Ketamine in patients with Treatment-resistant Depression: The ELEKT-D study protocol. Contemporary Clinical Trials. PMID 30572160 DOI: 10.1016/j.cct.2018.12.009  0.6
2018 Wilkinson ST, Sanacora G. A new generation of antidepressants: an update on the pharmaceutical pipeline for novel and rapid-acting therapeutics in mood disorders based on glutamate/GABA neurotransmitter systems. Drug Discovery Today. PMID 30447328 DOI: 10.1016/j.drudis.2018.11.007  0.6
2018 Fava M, Freeman MP, Flynn M, Judge H, Hoeppner BB, Cusin C, Ionescu DF, Mathew SJ, Chang LC, Iosifescu DV, Murrough J, Debattista C, Schatzberg AF, Trivedi MH, Jha MK, ... Sanacora G, et al. Double-blind, placebo-controlled, dose-ranging trial of intravenous ketamine as adjunctive therapy in treatment-resistant depression (TRD). Molecular Psychiatry. PMID 30283029 DOI: 10.1038/s41380-018-0256-5  0.6
2018 Wilkinson ST, Katz RB, Toprak M, Webler R, Ostroff RB, Sanacora G. Acute and Longer-Term Outcomes Using Ketamine as a Clinical Treatment at the Yale Psychiatric Hospital. The Journal of Clinical Psychiatry. 79. PMID 30063304 DOI: 10.4088/JCP.17m11731  0.6
2018 Abdallah CG, De Feyter HM, Averill LA, Jiang L, Averill CL, Chowdhury GMI, Purohit P, de Graaf RA, Esterlis I, Juchem C, Pittman BP, Krystal JH, Rothman DL, Sanacora G, Mason GF. The effects of ketamine on prefrontal glutamate neurotransmission in healthy and depressed subjects. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. PMID 29977074 DOI: 10.1038/s41386-018-0136-3  0.88
2018 Abdallah CG, Sanacora G, Duman RS, Krystal JH. The neurobiology of depression, ketamine and rapid-acting antidepressants: Is it glutamate inhibition or activation? Pharmacology & Therapeutics. PMID 29803629 DOI: 10.1016/j.pharmthera.2018.05.010  0.92
2018 Wilkinson ST, Sanacora G. Authorship Credit for Large Clinical Trials. Jama. 319: 722-723. PMID 29466586 DOI: 10.1001/jama.2017.20939  0.6
2017 van Schalkwyk GI, Wilkinson ST, Davidson L, Silverman WK, Sanacora G. Acute psychoactive effects of intravenous ketamine during treatment of mood disorders: Analysis of the Clinician Administered Dissociative State Scale. Journal of Affective Disorders. 227: 11-16. PMID 29045915 DOI: 10.1016/j.jad.2017.09.023  0.6
2017 Abdallah CG, Hannestad J, Mason GF, Holmes SE, DellaGioia N, Sanacora G, Jiang L, Matuskey D, Satodiya R, Gasparini F, Lin X, Javitch J, Planeta B, Nabulsi N, Carson RE, et al. Metabotropic Glutamate Receptor 5 and Glutamate Involvement in Major Depressive Disorder: A Multimodal Imaging Study. Biological Psychiatry. Cognitive Neuroscience and Neuroimaging. 2: 449-456. PMID 28993818 DOI: 10.1016/j.bpsc.2017.03.019  0.76
2017 Wilkinson ST, Sanacora G, Bloch MH. Hippocampal volume changes following electroconvulsive therapy: a systematic review and meta-analysis. Biological Psychiatry. Cognitive Neuroscience and Neuroimaging. 2: 327-335. PMID 28989984 DOI: 10.1016/j.bpsc.2017.01.011  0.64
2017 Wilkinson ST, Ballard ED, Bloch MH, Mathew SJ, Murrough JW, Feder A, Sos P, Wang G, Zarate CA, Sanacora G. The Effect of a Single Dose of Intravenous Ketamine on Suicidal Ideation: A Systematic Review and Individual Participant Data Meta-Analysis. The American Journal of Psychiatry. appiajp201717040472. PMID 28969441 DOI: 10.1176/appi.ajp.2017.17040472  0.64
2017 Krystal JH, Abdallah CG, Averill LA, Kelmendi B, Harpaz-Rotem I, Sanacora G, Southwick SM, Duman RS. Synaptic Loss and the Pathophysiology of PTSD: Implications for Ketamine as a Prototype Novel Therapeutic. Current Psychiatry Reports. 19: 74. PMID 28844076 DOI: 10.1007/s11920-017-0829-z  0.92
2017 Banasr M, Lepack A, Fee C, Duric V, Maldonado-Aviles J, DiLeone R, Sibille E, Duman RS, Sanacora G. Characterization of GABAergic marker expression in the chronic unpredictable stress model of depression. Chronic Stress (Thousand Oaks, Calif.). 1. PMID 28835932  0.92
2017 Wilkinson ST, Sanacora G. Considerations on the Off-Label Use of Ketamine as a Treatment for Mood Disorders. Jama. PMID 28806440 DOI: 10.1001/jama.2017.10697  0.6
2017 Wilkinson ST, Toprak M, Turner MS, Levine SP, Katz RB, Sanacora G. A Survey of the Clinical, Off-Label Use of Ketamine as a Treatment for Psychiatric Disorders. The American Journal of Psychiatry. 174: 695-696. PMID 28669202 DOI: 10.1176/appi.ajp.2017.17020239  0.6
2017 Mathew SJ, Gueorguieva R, Brandt C, Fava M, Sanacora G. A Randomized, Double-Blind, Placebo-Controlled, Sequential Parallel Comparison Design Trial of Adjunctive Riluzole for Treatment-Resistant Major Depressive Disorder. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. PMID 28553836 DOI: 10.1038/npp.2017.106  0.32
2017 Wilkinson ST, Wright D, Fasula MK, Fenton L, Griepp M, Ostroff RB, Sanacora G. Cognitive Behavior Therapy May Sustain Antidepressant Effects of Intravenous Ketamine in Treatment-Resistant Depression. Psychotherapy and Psychosomatics. 86: 162-167. PMID 28490030 DOI: 10.1159/000457960  0.6
2017 Klingensmith KE, Sanacora G, Ostroff R. Co-occurring Catatonia and Posterior Reversible Encephalopathy Syndrome Responsive to Electroconvulsive Therapy. The Journal of Ect. PMID 28383349 DOI: 10.1097/YCT.0000000000000407  0.36
2017 Medeiros da Frota Ribeiro C, Sanacora G, Ostroff R. Reply to: Ketamine and Psychosis History: Antidepressant Efficacy and Psychotomimetic Effects Postinfusion. Biological Psychiatry. PMID 28262251 DOI: 10.1016/j.biopsych.2017.01.012  0.36
2016 Wilkinson ST, Ostroff RB, Sanacora G. Computer-Assisted Cognitive Behavior Therapy to Prevent Relapse Following Electroconvulsive Therapy. The Journal of Ect. PMID 27564424 DOI: 10.1097/YCT.0000000000000348  0.6
2016 Krystal JH, Abi-Dargham A, Akbarian S, Arnsten AF, Barch DM, Bearden CE, Braff DL, Brown ES, Bullmore ET, Carlezon WA, Carter CS, Cook EH, Daskalakis ZJ, DiLeone RJ, Duman RS, ... ... Sanacora G, et al. Constance E. Lieber, Theodore R. Stanley, and the Enduring Impact of Philanthropy on Psychiatry Research. Biological Psychiatry. 80: 84-6. PMID 27346079 DOI: 10.1016/j.biopsych.2016.05.004  0.92
2016 Sanacora G. What Are We Learning From Early-Phase Clinical Trials With Glutamate Targeting Medications for the Treatment of Major Depressive Disorder. Jama Psychiatry. PMID 27303925 DOI: 10.1001/jamapsychiatry.2016.0780  0.96
2016 Wilkinson ST, Sanacora G. KETAMINE: A POTENTIAL RAPID-ACTING ANTISUICIDAL AGENT? Depression and Anxiety. PMID 27082101 DOI: 10.1002/da.22498  0.96
2016 Chowdhury GM, Zhang J, Thomas M, Banasr M, Ma X, Pittman B, Bristow L, Schaeffer E, Duman RS, Rothman DL, Behar KL, Sanacora G. Transiently increased glutamate cycling in rat PFC is associated with rapid onset of antidepressant-like effects. Molecular Psychiatry. PMID 27067013 DOI: 10.1038/mp.2016.34  0.96
2016 Abdallah CG, Adams TG, Kelmendi B, Esterlis I, Sanacora G, Krystal JH. KETAMINE'S MECHANISM OF ACTION: A PATH TO RAPID-ACTING ANTIDEPRESSANTS. Depression and Anxiety. PMID 27062302 DOI: 10.1002/da.22501  0.96
2016 Duman RS, Aghajanian GK, Sanacora G, Krystal JH. Synaptic plasticity and depression: new insights from stress and rapid-acting antidepressants. Nature Medicine. 22: 238-49. PMID 26937618 DOI: 10.1038/nm.4050  0.92
2015 Niciu MJ, Abdallah CG, Fenton LR, Fasula MK, Black A, Anderson GM, Sanacora G. A history of early life parental loss or separation is associated with successful cognitive-behavioral therapy in major depressive disorder. Journal of Affective Disorders. 187: 241-4. PMID 26363143 DOI: 10.1016/j.jad.2015.08.026  0.76
2015 Pittenger C, Bloch MH, Wasylink S, Billingslea E, Simpson R, Jakubovski E, Kelmendi B, Sanacora G, Coric V. Riluzole augmentation in treatment-refractory obsessive-compulsive disorder: a pilot randomized placebo-controlled trial. The Journal of Clinical Psychiatry. 76: 1075-84. PMID 26214725 DOI: 10.4088/JCP.14m09123  0.64
2015 da Frota Ribeiro CM, Sanacora G, Hoffman R, Ostroff R. The Use of Ketamine for the Treatment of Depression in the Context of Psychotic Symptoms: To the Editor. Biological Psychiatry. PMID 26212896 DOI: 10.1016/j.biopsych.2015.05.016  0.36
2015 Sanacora G, Schatzberg AF. Ketamine: promising path or false prophecy in the development of novel therapeutics for mood disorders? Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 40: 1307. PMID 25767082 DOI: 10.1038/npp.2014.338  0.96
2015 McCullumsmith RE, Sanacora G. Regulation of extrasynaptic glutamate levels as a pathophysiological mechanism in disorders of motivation and addiction. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 40: 254-5. PMID 25482181 DOI: 10.1038/npp.2014.218  0.96
2015 Abdallah CG, Sanacora G, Duman RS, Krystal JH. Ketamine and rapid-acting antidepressants: a window into a new neurobiology for mood disorder therapeutics. Annual Review of Medicine. 66: 509-23. PMID 25341010 DOI: 10.1146/annurev-med-053013-062946  0.96
2015 Sanacora G, Schatzberg AF. Ketamine: promising path or false prophecy in the development of novel therapeutics for mood disorders? Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 40: 259-67. PMID 25257213 DOI: 10.1038/npp.2014.261  0.96
2015 DeLorenzo C, DellaGioia N, Bloch M, Sanacora G, Nabulsi N, Abdallah C, Yang J, Wen R, Mann JJ, Krystal JH, Parsey RV, Carson RE, Esterlis I. In vivo ketamine-induced changes in [¹¹C]ABP688 binding to metabotropic glutamate receptor subtype 5. Biological Psychiatry. 77: 266-75. PMID 25156701 DOI: 10.1016/j.biopsych.2014.06.024  0.96
2015 Pittenger C, Bloch MH, Wasylink S, Billingslea E, Simpson R, Jakubovski E, Kelmendi B, Sanacora G, Coric V. Riluzole augmentation in treatment-refractory obsessive-compulsive disorder: A pilot randomized placebo-controlled trial Journal of Clinical Psychiatry. 76: 1075-1084. DOI: 10.4088/JCP.14m09123  0.96
2015 Niciu MJ, Abdallah CG, Fenton LR, Fasula MK, Black A, Anderson GM, Sanacora G. A history of early life parental loss or separation is associated with successful cognitive-behavioral therapy in major depressive disorder Journal of Affective Disorders. 187: 241-244. DOI: 10.1016/j.jad.2015.08.026  0.96
2015 Da Frota Ribeiro CM, Sanacora G, Hoffman R, Ostroff R. The Use of Ketamine for the Treatment of Depression in the Context of Psychotic Symptoms Biological Psychiatry. DOI: 10.1016/j.biopsych.2015.05.016  0.96
2014 Abdallah CG, Niciu MJ, Fenton LR, Fasula MK, Jiang L, Black A, Rothman DL, Mason GF, Sanacora G. Decreased occipital cortical glutamate levels in response to successful cognitive-behavioral therapy and pharmacotherapy for major depressive disorder. Psychotherapy and Psychosomatics. 83: 298-307. PMID 25116726 DOI: 10.1159/000361078  0.96
2014 Abdallah CG, Jiang L, De Feyter HM, Fasula M, Krystal JH, Rothman DL, Mason GF, Sanacora G. Glutamate metabolism in major depressive disorder. The American Journal of Psychiatry. 171: 1320-7. PMID 25073688 DOI: 10.1176/appi.ajp.2014.14010067  0.96
2014 Sanacora G, Smith MA, Pathak S, Su HL, Boeijinga PH, McCarthy DJ, Quirk MC. Lanicemine: a low-trapping NMDA channel blocker produces sustained antidepressant efficacy with minimal psychotomimetic adverse effects. Molecular Psychiatry. 19: 978-85. PMID 24126931 DOI: 10.1038/mp.2013.130  0.96
2014 Niciu MJ, Henter ID, Sanacora G, Zarate CA. Glial abnormalities in substance use disorders and depression: does shared glutamatergic dysfunction contribute to comorbidity? The World Journal of Biological Psychiatry : the Official Journal of the World Federation of Societies of Biological Psychiatry. 15: 2-16. PMID 24024876 DOI: 10.3109/15622975.2013.829585  0.96
2014 Kiselycznyk C, Sanacora G. Using our understanding of stress-related effects on glutamate neurotransmission to guide the development of novel treatment strategies Synaptic Stress and Pathogenesis of Neuropsychiatric Disorders. 313-342. DOI: 10.1007/978-1-4939-1056-4_17  0.96
2013 Voleti B, Navarria A, Liu RJ, Banasr M, Li N, Terwilliger R, Sanacora G, Eid T, Aghajanian G, Duman RS. Scopolamine rapidly increases mammalian target of rapamycin complex 1 signaling, synaptogenesis, and antidepressant behavioral responses. Biological Psychiatry. 74: 742-9. PMID 23751205 DOI: 10.1016/j.biopsych.2013.04.025  0.96
2013 Sanacora G, Banasr M. From pathophysiology to novel antidepressant drugs: glial contributions to the pathology and treatment of mood disorders. Biological Psychiatry. 73: 1172-9. PMID 23726152 DOI: 10.1016/j.biopsych.2013.03.032  0.96
2013 Krystal JH, Sanacora G, Duman RS. Rapid-acting glutamatergic antidepressants: the path to ketamine and beyond. Biological Psychiatry. 73: 1133-41. PMID 23726151 DOI: 10.1016/j.biopsych.2013.03.026  0.96
2013 Cardoos A, Inamori A, Sanacora G, Fava M, Mischoulon D. Delayed amnesic syndrome after riluzole use in major depressive disorder: a case report. Psychosomatics. 54: 488-92. PMID 23473447 DOI: 10.1016/j.psym.2013.02.002  0.96
2013 Sanacora G, Duman RS. The revolution in rapid-acting antidepressants Biological Psychiatry. 73: 1123-1124. DOI: 10.1016/j.biopsych.2013.04.020  0.96
2012 Abdallah CG, Fasula M, Kelmendi B, Sanacora G, Ostroff R. Rapid antidepressant effect of ketamine in the electroconvulsive therapy setting. The Journal of Ect. 28: 157-61. PMID 22847373 DOI: 10.1097/YCT.0b013e31824f8296  0.96
2012 Bloch MH, Wasylink S, Landeros-Weisenberger A, Panza KE, Billingslea E, Leckman JF, Krystal JH, Bhagwagar Z, Sanacora G, Pittenger C. Effects of ketamine in treatment-refractory obsessive-compulsive disorder. Biological Psychiatry. 72: 964-70. PMID 22784486 DOI: 10.1016/j.biopsych.2012.05.028  0.96
2012 Laje G, Lally N, Mathews D, Brutsche N, Chemerinski A, Akula N, Kelmendi B, Simen A, McMahon FJ, Sanacora G, Zarate C. Brain-derived neurotrophic factor Val66Met polymorphism and antidepressant efficacy of ketamine in depressed patients. Biological Psychiatry. 72: e27-8. PMID 22771240 DOI: 10.1016/j.biopsych.2012.05.031  0.96
2012 Morgan PT, Pace-Schott EF, Mason GF, Forselius E, Fasula M, Valentine GW, Sanacora G. Cortical GABA levels in primary insomnia. Sleep. 35: 807-14. PMID 22654200 DOI: 10.5665/sleep.1880  0.96
2012 McCarthy DJ, Alexander R, Smith MA, Pathak S, Kanes S, Lee CM, Sanacora G. Glutamate-based depression GBD. Medical Hypotheses. 78: 675-81. PMID 22391030 DOI: 10.1016/j.mehy.2012.02.009  0.96
2012 Chowdhury GM, Behar KL, Cho W, Thomas MA, Rothman DL, Sanacora G. ¹H-[¹³C]-nuclear magnetic resonance spectroscopy measures of ketamine's effect on amino acid neurotransmitter metabolism. Biological Psychiatry. 71: 1022-5. PMID 22169441 DOI: 10.1016/j.biopsych.2011.11.006  0.96
2012 Popoli M, Yan Z, McEwen BS, Sanacora G. The stressed synapse: the impact of stress and glucocorticoids on glutamate transmission. Nature Reviews. Neuroscience. 13: 22-37. PMID 22127301 DOI: 10.1038/nrn3138  0.96
2012 Siegel S, Sanacora G. The roles of glutamate receptors across major neurological and psychiatric disorders. Pharmacology, Biochemistry, and Behavior. 100: 653-5. PMID 22108650 DOI: 10.1016/j.pbb.2011.11.002  0.96
2012 Niciu MJ, Kelmendi B, Sanacora G. Overview of glutamatergic neurotransmission in the nervous system. Pharmacology, Biochemistry, and Behavior. 100: 656-64. PMID 21889952 DOI: 10.1016/j.pbb.2011.08.008  0.96
2012 Gomez R, Behar KL, Watzl J, Weinzimer SA, Gulanski B, Sanacora G, Koretski J, Guidone E, Jiang L, Petrakis IL, Pittman B, Krystal JH, Mason GF. Intravenous ethanol infusion decreases human cortical γ-aminobutyric acid and N-acetylaspartate as measured with proton magnetic resonance spectroscopy at 4 tesla. Biological Psychiatry. 71: 239-46. PMID 21855054 DOI: 10.1016/j.biopsych.2011.06.026  0.96
2012 Sanacora G, Treccani G, Popoli M. Towards a glutamate hypothesis of depression: an emerging frontier of neuropsychopharmacology for mood disorders. Neuropharmacology. 62: 63-77. PMID 21827775 DOI: 10.1016/j.neuropharm.2011.07.036  0.96
2012 Gourley SL, Espitia JW, Sanacora G, Taylor JR. Antidepressant-like properties of oral riluzole and utility of incentive disengagement models of depression in mice. Psychopharmacology. 219: 805-14. PMID 21779782 DOI: 10.1007/s00213-011-2403-4  0.96
2012 Sanacora G. Ketamine-induced optimism: New hope for the development of rapid-acting antidepressants Psychiatric Times. 29: 1+3-7.  0.96
2011 Kelmendi B, Holsbach-Beltrame M, McIntosh AM, Hilt L, George ED, Kitchen RR, Carlyle BC, Pittenger C, Coric V, Nolen-Hoeksema S, Sanacora G, Simen AA. Association of polymorphisms in HCN4 with mood disorders and obsessive compulsive disorder. Neuroscience Letters. 496: 195-9. PMID 21529705 DOI: 10.1016/j.neulet.2011.04.026  0.96
2011 Valentine GW, Mason GF, Gomez R, Fasula M, Watzl J, Pittman B, Krystal JH, Sanacora G. The antidepressant effect of ketamine is not associated with changes in occipital amino acid neurotransmitter content as measured by [(1)H]-MRS. Psychiatry Research. 191: 122-7. PMID 21232924 DOI: 10.1016/j.pscychresns.2010.10.009  0.96
2011 Saricicek A, Maloney K, Muralidharan A, Ruf B, Blumberg HP, Sanacora G, Lorberg B, Pittman B, Bhagwagar Z. Levetiracetam in the management of bipolar depression: a randomized, double-blind, placebo-controlled trial. The Journal of Clinical Psychiatry. 72: 744-50. PMID 21034692 DOI: 10.4088/JCP.09m05659gre  0.96
2010 Husky MM, Gindre C, Mazure CM, Brebant C, Nolen-Hoeksema S, Sanacora G, Swendsen J. Computerized ambulatory monitoring in mood disorders: feasibility, compliance, and reactivity. Psychiatry Research. 178: 440-2. PMID 20488558 DOI: 10.1016/j.psychres.2010.04.045  0.96
2010 Sanacora G. Cortical inhibition, gamma-aminobutyric acid, and major depression: there is plenty of smoke but is there fire? Biological Psychiatry. 67: 397-8. PMID 20159143 DOI: 10.1016/j.biopsych.2010.01.003  0.96
2010 Maciag D, Hughes J, O'Dwyer G, Pride Y, Stockmeier CA, Sanacora G, Rajkowska G. Reduced density of calbindin immunoreactive GABAergic neurons in the occipital cortex in major depression: relevance to neuroimaging studies. Biological Psychiatry. 67: 465-70. PMID 20004363 DOI: 10.1016/j.biopsych.2009.10.027  0.96
2010 Banasr M, Chowdhury GM, Terwilliger R, Newton SS, Duman RS, Behar KL, Sanacora G. Glial pathology in an animal model of depression: reversal of stress-induced cellular, metabolic and behavioral deficits by the glutamate-modulating drug riluzole. Molecular Psychiatry. 15: 501-11. PMID 18825147 DOI: 10.1038/mp.2008.106  0.96
2010 Krystal JH, Tolin DF, Sanacora G, Castner SA, Williams GV, Aikins DE, Hoffman RE, D'Souza DC. Neuroplasticity as a target of the pharmacotherapy of anxiety disorders, mood disorders and schizophrenia | Neuroplastyczność jako cel dla farmakoterapii zaburzeń lȩkowych, zaburzeń nastroju i schizofrenii Wiadomosci Psychiatryczne. 13: 163-173.  0.96
2009 Sanacora G. Do glutamatergic agents represent a new class of antidepressant drugs? Part 2. The Journal of Clinical Psychiatry. 70: 1604-5. PMID 20031105 DOI: 10.4088/JCP.09ac05757blu  0.96
2009 Krystal JH, Tolin DF, Sanacora G, Castner SA, Williams GV, Aikins DE, Hoffman RE, D'Souza DC. Neuroplasticity as a target for the pharmacotherapy of anxiety disorders, mood disorders, and schizophrenia. Drug Discovery Today. 14: 690-7. PMID 19460458 DOI: 10.1016/j.drudis.2009.05.002  0.96
2009 Valentine GW, Sanacora G. Targeting glial physiology and glutamate cycling in the treatment of depression. Biochemical Pharmacology. 78: 431-9. PMID 19376090 DOI: 10.1016/j.bcp.2009.04.008  0.96
2008 Sanacora G. New understanding of mechanisms of action of bipolar medications. The Journal of Clinical Psychiatry. 69: 22-7. PMID 19265637  0.96
2008 Sen S, Sanacora G. Major depression: emerging therapeutics. The Mount Sinai Journal of Medicine, New York. 75: 204-25. PMID 18704976 DOI: 10.1002/msj.20043  0.96
2008 Pittenger C, Coric V, Banasr M, Bloch M, Krystal JH, Sanacora G. Riluzole in the treatment of mood and anxiety disorders. Cns Drugs. 22: 761-86. PMID 18698875 DOI: 10.2165/00023210-200822090-00004  0.96
2008 Chowdhury GM, Banasr M, de Graaf RA, Rothman DL, Behar KL, Sanacora G. Chronic riluzole treatment increases glucose metabolism in rat prefrontal cortex and hippocampus. Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism. 28: 1892-7. PMID 18628780 DOI: 10.1038/jcbfm.2008.78  0.96
2008 Sen S, Duman R, Sanacora G. Serum brain-derived neurotrophic factor, depression, and antidepressant medications: meta-analyses and implications. Biological Psychiatry. 64: 527-32. PMID 18571629 DOI: 10.1016/j.biopsych.2008.05.005  0.96
2008 Sanacora G, Zarate CA, Krystal JH, Manji HK. Targeting the glutamatergic system to develop novel, improved therapeutics for mood disorders. Nature Reviews. Drug Discovery. 7: 426-37. PMID 18425072 DOI: 10.1038/nrd2462  0.96
2008 Krystal JH, Carter CS, Geschwind D, Manji HK, March JS, Nestler EJ, Zubieta JK, Charney DS, Goldman D, Gur RE, Lieberman JA, Roy-Byrne P, Rubinow DR, Anderson SA, Barondes S, ... ... Sanacora G, et al. It is time to take a stand for medical research and against terrorism targeting medical scientists. Biological Psychiatry. 63: 725-7. PMID 18371494 DOI: 10.1016/j.biopsych.2008.03.005  1
2008 Nierenberg AA, Ketter TA, Perlis RH, Sanacora G, Thase ME. Easing the burden of bipolar disorder: From urgent situations to remission Primary Care Companion to the Journal of Clinical Psychiatry. 10: 391-402.  0.96
2007 Sanacora G, Saricicek A. GABAergic contributions to the pathophysiology of depression and the mechanism of antidepressant action. Cns & Neurological Disorders Drug Targets. 6: 127-40. PMID 17430150 DOI: 10.2174/187152707780363294  0.96
2007 Pittenger C, Sanacora G, Krystal JH. The NMDA receptor as a therapeutic target in major depressive disorder. Cns & Neurological Disorders Drug Targets. 6: 101-15. PMID 17430148 DOI: 10.2174/187152707780363267  0.96
2007 Sanacora G, Kendell SF, Levin Y, Simen AA, Fenton LR, Coric V, Krystal JH. Preliminary evidence of riluzole efficacy in antidepressant-treated patients with residual depressive symptoms. Biological Psychiatry. 61: 822-5. PMID 17141740 DOI: 10.1016/j.biopsych.2006.08.037  0.96
2007 Mineur YS, Picciotto MR, Sanacora G. Antidepressant-like effects of ceftriaxone in male C57BL/6J mice. Biological Psychiatry. 61: 250-2. PMID 16860779 DOI: 10.1016/j.biopsych.2006.04.037  0.96
2006 Fenton L, Fasula M, Ostroff R, Sanacora G. Can cognitive behavioral therapy reduce relapse rates of depression after ECT? a preliminary study. The Journal of Ect. 22: 196-8. PMID 16957536 DOI: 10.1097/01.yct.0000235201.42287.b4  0.96
2006 Pittenger C, Naungayan C, Kendell SF, Coric V, Malison R, Krystal JH, Sanacora GS. Visual hallucinations from the addition of riluzole to memantine and bupropion. Journal of Clinical Psychopharmacology. 26: 218-20. PMID 16633160 DOI: 10.1097/01.jcp.0000203228.64117.9f  0.96
2006 Geracioti TD, Carpenter LL, Owens MJ, Baker DG, Ekhator NN, Horn PS, Strawn JR, Sanacora G, Kinkead B, Price LH, Nemeroff CB. Elevated cerebrospinal fluid substance p concentrations in posttraumatic stress disorder and major depression. The American Journal of Psychiatry. 163: 637-43. PMID 16585438 DOI: 10.1176/appi.ajp.163.4.637  0.96
2006 Lafleur DL, Pittenger C, Kelmendi B, Gardner T, Wasylink S, Malison RT, Sanacora G, Krystal JH, Coric V. N-acetylcysteine augmentation in serotonin reuptake inhibitor refractory obsessive-compulsive disorder. Psychopharmacology. 184: 254-6. PMID 16374600 DOI: 10.1007/s00213-005-0246-6  0.96
2006 Gueorguieva RV, Sanacora G. Joint analysis of repeatedly observed continuous and ordinal measures of disease severity. Statistics in Medicine. 25: 1307-22. PMID 16217846 DOI: 10.1002/sim.2270  0.96
2006 Staley JK, Sanacora G, Tamagnan G, Maciejewski PK, Malison RT, Berman RM, Vythilingam M, Kugaya A, Baldwin RM, Seibyl JP, Charney D, Innis RB. Sex differences in diencephalon serotonin transporter availability in major depression. Biological Psychiatry. 59: 40-7. PMID 16139815 DOI: 10.1016/j.biopsych.2005.06.012  0.96
2006 Sanacora G, Fenton LR, Fasula MK, Rothman DL, Levin Y, Krystal JH, Mason GF. Cortical gamma-aminobutyric acid concentrations in depressed patients receiving cognitive behavioral therapy. Biological Psychiatry. 59: 284-6. PMID 16139814 DOI: 10.1016/j.biopsych.2005.07.015  0.96
2006 Kelmendi B, Saricicek A, Sanacora G. The role of the glutamatergic system in the pathophysiology and treatment of mood disorders Primary Psychiatry. 13: 80-86.  0.96
2005 Kugaya A, Sanacora G. Beyond monoamines: glutamatergic function in mood disorders. Cns Spectrums. 10: 808-19. PMID 16400244  0.96
2005 Ostroff R, Gonzales M, Sanacora G. Antidepressant effect of ketamine during ECT. The American Journal of Psychiatry. 162: 1385-6. PMID 15994728 DOI: 10.1176/appi.ajp.162.7.1385  0.96
2005 Coric V, Taskiran S, Pittenger C, Wasylink S, Mathalon DH, Valentine G, Saksa J, Wu YT, Gueorguieva R, Sanacora G, Malison RT, Krystal JH. Riluzole augmentation in treatment-resistant obsessive-compulsive disorder: an open-label trial. Biological Psychiatry. 58: 424-8. PMID 15993857 DOI: 10.1016/j.biopsych.2005.04.043  0.96
2005 Kendell SF, Krystal JH, Sanacora G. GABA and glutamate systems as therapeutic targets in depression and mood disorders. Expert Opinion On Therapeutic Targets. 9: 153-68. PMID 15757488 DOI: 10.1517/14728222.9.1.153  0.96
2005 Epperson CN, O'Malley S, Czarkowski KA, Gueorguieva R, Jatlow P, Sanacora G, Rothman DL, Krystal JH, Mason GF. Sex, GABA, and nicotine: the impact of smoking on cortical GABA levels across the menstrual cycle as measured with proton magnetic resonance spectroscopy. Biological Psychiatry. 57: 44-8. PMID 15607299 DOI: 10.1016/j.biopsych.2004.09.021  0.96
2005 Sabharwal P, Simen BB, Sanacora G. Depressed diabetics: A neuroimmunologic syndrome? Primary Psychiatry. 12: 42-46.  0.96
2004 Sanacora G, Kendell SF, Fenton L, Coric V, Krystal JH. Riluzole augmentation for treatment-resistant depression. The American Journal of Psychiatry. 161: 2132. PMID 15514421 DOI: 10.1176/appi.ajp.161.11.2132  0.96
2004 Kugaya A, Sanacora G, Staley JK, Malison RT, Bozkurt A, Khan S, Anand A, Van Dyck CH, Baldwin RM, Seibyl JP, Charney D, Innis RB. Brain serotonin transporter availability predicts treatment response to selective serotonin reuptake inhibitors. Biological Psychiatry. 56: 497-502. PMID 15450785 DOI: 10.1016/j.biopsych.2004.07.001  0.96
2004 Sanacora G, Gueorguieva R, Epperson CN, Wu YT, Appel M, Rothman DL, Krystal JH, Mason GF. Subtype-specific alterations of gamma-aminobutyric acid and glutamate in patients with major depression. Archives of General Psychiatry. 61: 705-13. PMID 15237082 DOI: 10.1001/archpsyc.61.7.705  0.96
2004 Sanacora G, Berman RM, Cappiello A, Oren DA, Kugaya A, Liu N, Gueorguieva R, Fasula D, Charney DS. Addition of the alpha2-antagonist yohimbine to fluoxetine: effects on rate of antidepressant response. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 29: 1166-71. PMID 15010697 DOI: 10.1038/sj.npp.1300418  0.96
2004 Perry EB, Berman RM, Sanacora G, Anand A, Lynch-Colonese K, Charney DS. Pindolol augmentation in depressed patients resistant to selective serotonin reuptake inhibitors: a double-blind, randomized, controlled trial. The Journal of Clinical Psychiatry. 65: 238-43. PMID 15003079 DOI: 10.4088/JCP.v65n0215  0.96
2004 Lappalainen J, Sanacora G, Kranzler HR, Malison R, Hibbard ES, Price LH, Krystal J, Gelernter J. Mutation screen of the glutamate decarboxylase-67 gene and haplotype association to unipolar depression. American Journal of Medical Genetics. Part B, Neuropsychiatric Genetics : the Official Publication of the International Society of Psychiatric Genetics. 124: 81-6. PMID 14681921 DOI: 10.1002/ajmg.b.20055  0.96
2003 Sanacora G, Rothman DL, Mason G, Krystal JH. Clinical studies implementing glutamate neurotransmission in mood disorders. Annals of the New York Academy of Sciences. 1003: 292-308. PMID 14684453 DOI: 10.1196/annals.1300.018  0.96
2003 Kugaya A, Sanacora G, Verhoeff NP, Fujita M, Mason GF, Seneca NM, Bozkurt A, Khan SA, Anand A, Degen K, Charney DS, Zoghbi SS, Baldwin RM, Seibyl JP, Innis RB. Cerebral benzodiazepine receptors in depressed patients measured with [123I]iomazenil SPECT. Biological Psychiatry. 54: 792-9. PMID 14550678 DOI: 10.1016/S0006-3223(02)01788-2  0.96
2003 Sanacora G, Mason GF, Rothman DL, Hyder F, Ciarcia JJ, Ostroff RB, Berman RM, Krystal JH. Increased cortical GABA concentrations in depressed patients receiving ECT. The American Journal of Psychiatry. 160: 577-9. PMID 12611844 DOI: 10.1176/appi.ajp.160.3.577  0.96
2002 Krystal JH, Sanacora G, Blumberg H, Anand A, Charney DS, Marek G, Epperson CN, Goddard A, Mason GF. Glutamate and GABA systems as targets for novel antidepressant and mood-stabilizing treatments. Molecular Psychiatry. 7: S71-80. PMID 11986998 DOI: 10.1038/sj.mp.4001021  0.96
2002 Sanacora G, Mason GF, Rothman DL, Krystal JH. Increased occipital cortex GABA concentrations in depressed patients after therapy with selective serotonin reuptake inhibitors. The American Journal of Psychiatry. 159: 663-5. PMID 11925309 DOI: 10.1176/appi.ajp.159.4.663  0.96
2002 Berman RM, Sanacora G, Anand A, Roach LM, Fasula MK, Finkelstein CO, Wachen RM, Oren DA, Heninger GR, Charney DS. Monoamine depletion in unmedicated depressed subjects. Biological Psychiatry. 51: 469-73. PMID 11922881 DOI: 10.1016/S0006-3223(01)01285-9  0.96
2002 Cubells JF, Price LH, Meyers BS, Anderson GM, Zabetian CP, Alexopoulos GS, Nelson JC, Sanacora G, Kirwin P, Carpenter L, Malison RT, Gelernter J. Genotype-controlled analysis of plasma dopamine beta-hydroxylase activity in psychotic unipolar major depression. Biological Psychiatry. 51: 358-64. PMID 11904129 DOI: 10.1016/S0006-3223(01)01349-X  0.96
2001 Krystal JH, D'Souza DC, Sanacora G, Goddard AW, Charney DS. Current perspectives on the pathophysiology of schizophrenia, depression, and anxiety disorders. The Medical Clinics of North America. 85: 559-77. PMID 11349473 DOI: 10.1016/S0025-7125(05)70329-1  0.96
2001 Chen AC, Shin KH, Duman RS, Sanacora G. ECS-Induced mossy fiber sprouting and BDNF expression are attenuated by ketamine pretreatment. The Journal of Ect. 17: 27-32. PMID 11281511 DOI: 10.1097/00124509-200103000-00006  0.96
2000 Sanacora G, Mason GF, Krystal JH. Impairment of GABAergic transmission in depression: new insights from neuroimaging studies. Critical Reviews in Neurobiology. 14: 23-45. PMID 11253954  0.96
2000 Berman RM, Narasimhan M, Sanacora G, Miano AP, Hoffman RE, Hu XS, Charney DS, Boutros NN. A randomized clinical trial of repetitive transcranial magnetic stimulation in the treatment of major depression. Biological Psychiatry. 47: 332-7. PMID 10686268 DOI: 10.1016/S0006-3223(99)00243-7  0.96
1999 Sanacora G, Mason GF, Rothman DL, Behar KL, Hyder F, Petroff OA, Berman RM, Charney DS, Krystal JH. Reduced cortical gamma-aminobutyric acid levels in depressed patients determined by proton magnetic resonance spectroscopy. Archives of General Psychiatry. 56: 1043-7. PMID 10565505 DOI: 10.1001/archpsyc.56.11.1043  0.96
1999 Sanacora G, Rothman D, Krystal JH. Applications of magnetic resonance spectroscopy to psychiatry Neuroscientist. 5: 192-196. DOI: 10.1177/107385849900500316  0.96
1998 Malison RT, Price LH, Berman R, van Dyck CH, Pelton GH, Carpenter L, Sanacora G, Owens MJ, Nemeroff CB, Rajeevan N, Baldwin RM, Seibyl JP, Innis RB, Charney DS. Reduced brain serotonin transporter availability in major depression as measured by [123I]-2 beta-carbomethoxy-3 beta-(4-iodophenyl)tropane and single photon emission computed tomography. Biological Psychiatry. 44: 1090-8. PMID 9836013 DOI: 10.1016/S0006-3223(98)00272-8  0.96
1996 Chang R, Sanacora G, Sanchez R. The need for outcome studies. Journal of the American Academy of Child and Adolescent Psychiatry. 35: 557. PMID 8935198  0.96
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