Year |
Citation |
Score |
2023 |
Landry O, François A, Oye Mintsa Mi-Mba MF, Traversy MT, Tremblay C, Emond V, Bennett DA, Gylys KH, Buxbaum JD, Calon F. Postsynaptic protein Shank3a deficiency synergizes with Alzheimer's disease neuropathology to impair cognitive performance in the 3xTg-AD murine model. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. PMID 37253603 DOI: 10.1523/JNEUROSCI.1945-22.2023 |
0.414 |
|
2021 |
Cohn W, Melnik M, Huang C, Teter B, Chandra S, Zhu C, McIntire LB, John V, Gylys KH, Bilousova T. Multi-Omics Analysis of Microglial Extracellular Vesicles From Human Alzheimer's Disease Brain Tissue Reveals Disease-Associated Signatures. Frontiers in Pharmacology. 12: 766082. PMID 34925024 DOI: 10.3389/fphar.2021.766082 |
0.407 |
|
2021 |
Miyoshi E, Bilousova T, Melnik M, Fakhrutdinov D, Poon WW, Vinters HV, Miller CA, Corrada M, Kawas C, Bohannan R, Caraway C, Elias C, Maina KN, Campagna JJ, John V, ... Gylys KH, et al. Exosomal tau with seeding activity is released from Alzheimer's disease synapses, and seeding potential is associated with amyloid beta. Laboratory Investigation; a Journal of Technical Methods and Pathology. PMID 34462532 DOI: 10.1038/s41374-021-00644-z |
0.486 |
|
2020 |
Bilousova T, Simmons BJ, Knapp RR, Elias CJ, Campagna J, Melnik M, Chandra S, Focht S, Zhu C, Vadivel K, Jagodzinska B, Cohn W, Spilman P, Gylys KH, Garg NK, et al. Dual Neutral Sphingomyelinase-2/Acetylcholinesterase Inhibitors for the treatment of Alzheimer's disease. Acs Chemical Biology. PMID 32352753 DOI: 10.1021/Acschembio.0C00311 |
0.302 |
|
2019 |
Bilousova T, Melnik M, Miyoshi E, Gonzalez BL, Poon WW, Vinters HV, Miller CA, Corrada MM, Kawas C, Hatami A, Albay R, Glabe C, Gylys KH. Apolipoprotein E/Aβ Complex Accumulates in AD Cortical Synapses via apoE Receptors and Is Enhanced by APOE4. The American Journal of Pathology. PMID 31108099 DOI: 10.1016/J.Ajpath.2019.04.010 |
0.508 |
|
2018 |
Ma QL, Teng E, Zuo X, Jones M, Teter B, Zhao EY, Zhu C, Bilousova T, Gylys KH, Apostolova LG, LaDu MJ, Hossain MA, Frautschy SA, Cole GM. Neuronal pentraxin 1: A synaptic-derived plasma biomarker in Alzheimer's disease. Neurobiology of Disease. PMID 29501530 DOI: 10.1016/J.Nbd.2018.02.014 |
0.412 |
|
2017 |
Abud EM, Ramirez RN, Martinez ES, Healy LM, Nguyen CHH, Newman SA, Yeromin AV, Scarfone VM, Marsh SE, Fimbres C, Caraway CA, Fote GM, Madany AM, Agrawal A, Kayed R, ... Gylys KH, et al. iPSC-Derived Human Microglia-like Cells to Study Neurological Diseases. Neuron. 94: 278-293.e9. PMID 28426964 DOI: 10.1016/J.Neuron.2017.03.042 |
0.308 |
|
2017 |
Gylys KH, Bilousova T. Flow Cytometry Analysis and Quantitative Characterization of Tau in Synaptosomes from Alzheimer's Disease Brains. Methods in Molecular Biology (Clifton, N.J.). 1523: 273-284. PMID 27975256 DOI: 10.1007/978-1-4939-6598-4_16 |
0.337 |
|
2016 |
Prieto GA, Trieu BH, Dang CT, Bilousova T, Gylys KH, Berchtold NC, Lynch G, Cotman CW. Pharmacological rescue of long-term potentiation in Alzheimer diseased synapses. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. PMID 27986924 DOI: 10.1523/Jneurosci.2774-16.2016 |
0.331 |
|
2016 |
Bilousova T, Miller CA, Poon WW, Vinters HV, Corrada M, Kawas C, Hayden EY, Teplow DB, Glabe C, Albay R, Cole GM, Teng E, Gylys KH. Synaptic Amyloid-β Oligomers Precede p-Tau and Differentiate High Pathology Control Cases. The American Journal of Pathology. 186: 185-98. PMID 26718979 DOI: 10.1016/J.Ajpath.2015.09.018 |
0.596 |
|
2015 |
Lazaris A, Hwang KS, Goukasian N, Ramirez LM, Eastman J, Blanken AE, Teng E, Gylys K, Cole G, Saykin AJ, Shaw LM, Trojanowski JQ, Jagust WJ, Weiner MW, Apostolova LG, et al. Alzheimer risk genes modulate the relationship between plasma apoE and cortical PiB binding. Neurology. Genetics. 1: e22. PMID 27066559 DOI: 10.1212/Nxg.0000000000000022 |
0.411 |
|
2015 |
Hwang KS, Lazaris AS, Eastman JA, Teng E, Thompson PM, Gylys KH, Cole GM, Apostolova LG. Plasma BDNF levels associate with Pittsburgh compound B binding in the brain. Alzheimer's & Dementia : Diagnosis, Assessment & Disease Monitoring. 1: 187-193. PMID 26207261 DOI: 10.1016/J.Dadm.2015.01.005 |
0.35 |
|
2015 |
Wang DB, Kinoshita Y, Kinoshita C, Uo T, Sopher BL, Cudaback E, Keene CD, Bilousova T, Gylys K, Case A, Jayadev S, Wang HG, Garden GA, Morrison RS. Loss of endophilin-B1 exacerbates Alzheimer's disease pathology. Brain : a Journal of Neurology. 138: 2005-19. PMID 25981964 DOI: 10.1093/Brain/Awv128 |
0.395 |
|
2015 |
Teng E, Chow N, Hwang KS, Thompson PM, Gylys KH, Cole GM, Jack CR, Shaw LM, Trojanowski JQ, Soares HD, Weiner MW, Apostolova LG. Low plasma ApoE levels are associated with smaller hippocampal size in the Alzheimer's disease neuroimaging initiative cohort. Dementia and Geriatric Cognitive Disorders. 39: 154-66. PMID 25547651 DOI: 10.1159/000368982 |
0.327 |
|
2015 |
Sokolow S, Henkins KM, Bilousova T, Gonzalez B, Vinters HV, Miller CA, Cornwell L, Poon WW, Gylys KH. Pre-synaptic C-terminal truncated tau is released from cortical synapses in Alzheimer's disease. Journal of Neurochemistry. 133: 368-79. PMID 25393609 DOI: 10.1111/Jnc.12991 |
0.789 |
|
2015 |
Gylys KH, Bilousova T, Teng E, Vinters HV, Miller CA, Poon WW, Apostolova LG, Frautschy SA, John V, Bredesen DE, Cole GM. O2-06-03: Release of c-terminal truncated and intact tau from Alzheimer's disease cortical synapses Alzheimer's & Dementia. 11: P186-P187. DOI: 10.1016/J.Jalz.2015.07.161 |
0.426 |
|
2015 |
Gonzalez BL, Gylys KH, Bilousova T. P1-004: Lipidation in cortical synapses of Alzheimer's disease versus normal controls Alzheimer's & Dementia. 11: P337-P337. DOI: 10.1016/J.Jalz.2015.06.200 |
0.39 |
|
2014 |
Lazaris A, Hwang K, Eastman JA, Thompson P, Gylys K, Cole GM, Apostolova L, Sokolow S. Ad Risk Gene Minor Alleles Modulate Relationship Between Plasma Apoe And Pib Binding In The Brain Alzheimers & Dementia. 10. DOI: 10.1016/J.Jalz.2014.05.095 |
0.346 |
|
2013 |
Tai LM, Bilousova T, Jungbauer L, Roeske SK, Youmans KL, Yu C, Poon WW, Cornwell LB, Miller CA, Vinters HV, Van Eldik LJ, Fardo DW, Estus S, Bu G, Gylys KH, et al. Levels of soluble apolipoprotein E/amyloid-β (Aβ) complex are reduced and oligomeric Aβ increased with APOE4 and Alzheimer disease in a transgenic mouse model and human samples. The Journal of Biological Chemistry. 288: 5914-26. PMID 23293020 DOI: 10.1074/Jbc.M112.442103 |
0.397 |
|
2012 |
Ringman JM, Tomic JL, Coppola G, Elashoff D, Gylys KH, Glabe CG. Conformation-dependent oligomers in cerebrospinal fluid of presymptomatic familial Alzheimer's disease mutation carriers. Dementia and Geriatric Cognitive Disorders Extra. 2: 652-7. PMID 23341831 DOI: 10.1159/000345771 |
0.41 |
|
2012 |
Ringman JM, Frautschy SA, Teng E, Begum AN, Bardens J, Beigi M, Gylys KH, Badmaev V, Heath DD, Apostolova LG, Porter V, Vanek Z, Marshall GA, Hellemann G, Sugar C, et al. Oral curcumin for Alzheimer's disease: tolerability and efficacy in a 24-week randomized, double blind, placebo-controlled study. Alzheimer's Research & Therapy. 4: 43. PMID 23107780 DOI: 10.1186/Alzrt146 |
0.303 |
|
2012 |
Ringman JM, Fithian AT, Gylys K, Cummings JL, Coppola G, Elashoff D, Pratico D, Moskovitz J, Bitan G. Plasma methionine sulfoxide in persons with familial Alzheimer's disease mutations. Dementia and Geriatric Cognitive Disorders. 33: 219-25. PMID 22584618 DOI: 10.1159/000338546 |
0.375 |
|
2012 |
Henkins KM, Sokolow S, Miller CA, Vinters HV, Poon WW, Cornwell LB, Saing T, Gylys KH. Extensive p-tau pathology and SDS-stable p-tau oligomers in Alzheimer's cortical synapses. Brain Pathology (Zurich, Switzerland). 22: 826-33. PMID 22486774 DOI: 10.1111/J.1750-3639.2012.00598.X |
0.799 |
|
2012 |
Ringman JM, Coppola G, Elashoff D, Rodriguez-Agudelo Y, Medina LD, Gylys K, Cummings JL, Cole GM. Cerebrospinal fluid biomarkers and proximity to diagnosis in preclinical familial Alzheimer's disease. Dementia and Geriatric Cognitive Disorders. 33: 1-5. PMID 22343824 DOI: 10.1159/000335729 |
0.522 |
|
2012 |
Ringman JM, Schulman H, Becker C, Jones T, Bai Y, Immermann F, Cole G, Sokolow S, Gylys K, Geschwind DH, Cummings JL, Wan HI. Proteomic changes in cerebrospinal fluid of presymptomatic and affected persons carrying familial Alzheimer disease mutations. Archives of Neurology. 69: 96-104. PMID 22232349 DOI: 10.1001/Archneurol.2011.642 |
0.407 |
|
2012 |
Sokolow S, Henkins KM, Williams IA, Vinters HV, Schmid I, Cole GM, Gylys KH. Isolation of synaptic terminals from Alzheimer's disease cortex. Cytometry. Part a : the Journal of the International Society For Analytical Cytology. 81: 248-54. PMID 22213704 DOI: 10.1002/Cyto.A.22009 |
0.796 |
|
2012 |
Arold S, Sullivan P, Bilousova T, Teng E, Miller CA, Poon WW, Vinters HV, Cornwell LB, Saing T, Cole GM, Gylys KH. Apolipoprotein E level and cholesterol are associated with reduced synaptic amyloid beta in Alzheimer's disease and apoE TR mouse cortex. Acta Neuropathologica. 123: 39-52. PMID 22020632 DOI: 10.1007/S00401-011-0892-1 |
0.51 |
|
2012 |
Sokolow S, Luu SH, Nandy K, Miller CA, Vinters HV, Poon WW, Gylys KH. Preferential accumulation of amyloid-beta in presynaptic glutamatergic terminals (VGluT1 and VGluT2) in Alzheimer's disease cortex. Neurobiology of Disease. 45: 381-7. PMID 21914482 DOI: 10.1016/J.Nbd.2011.08.027 |
0.492 |
|
2012 |
Sokolow S, Henkins KM, Bilousova T, Miller CA, Vinters HV, Poon W, Cole GM, Gylys KH. AD synapses contain abundant Aβ monomer and multiple soluble oligomers, including a 56-kDa assembly. Neurobiology of Aging. 33: 1545-55. PMID 21741125 DOI: 10.1016/J.Neurobiolaging.2011.05.011 |
0.787 |
|
2011 |
Ringman JM, Taylor K, Teng E, Coppola G, Gylys K. Longitudinal change in CSF biomarkers in a presymptomatic carrier of an APP mutation. Neurology. 76: 2124-5. PMID 21562250 DOI: 10.1212/Wnl.0B013E31821F4488 |
0.49 |
|
2011 |
Sokolow S, Luu SH, Headley AJ, Hanson AY, Kim T, Miller CA, Vinters HV, Gylys KH. High levels of synaptosomal Na(+)-Ca(2+) exchangers (NCX1, NCX2, NCX3) co-localized with amyloid-beta in human cerebral cortex affected by Alzheimer's disease. Cell Calcium. 49: 208-16. PMID 21382638 DOI: 10.1016/J.Ceca.2010.12.008 |
0.404 |
|
2011 |
Ringman JM, Gylys KH, Medina LD, Fox M, Kepe V, Flores DL, Apostolova LG, Barrio JR, Small G, Silverman DH, Siu E, Cederbaum S, Hecimovic S, Malnar M, Chakraverty S, et al. Biochemical, neuropathological, and neuroimaging characteristics of early-onset Alzheimer's disease due to a novel PSEN1 mutation. Neuroscience Letters. 487: 287-92. PMID 21094210 DOI: 10.1016/J.Neulet.2010.10.039 |
0.367 |
|
2011 |
Chow N, Hwang K, Ringman J, Teng E, Thompson P, Cole G, Gylys K, Jack C, Shaw L, Trojanowski J, Soares H, Weiner M, Apostolova L. P2-027: Plasma protein associations with hippocampal atrophy across the cognitive spectrum from normal aging to Alzheimer's disease Alzheimer's & Dementia. 7: S315-S316. DOI: 10.1016/J.Jalz.2011.05.917 |
0.387 |
|
2011 |
Chow N, Hwang K, Teng E, Thompson P, Gylys K, Cole G, Jack C, Shaw L, Trojanowski J, Soares H, Weiner M, Apostolova L. Low serum levels of APOE associate with hippocampal atrophy in the ADNI cohort Alzheimers & Dementia. 7. DOI: 10.1016/J.Jalz.2011.05.916 |
0.302 |
|
2011 |
Teng E, Gylys K, Cole G, Ringman J, Elashoff D, Geschwind D. P1-120: APOE genotype differences in plasma protein levels in young and elderly cohorts Alzheimer's & Dementia. 7: S148-S148. DOI: 10.1016/J.Jalz.2011.05.400 |
0.301 |
|
2010 |
Henkins KM, Arold S, Sokolow S, Miller C, Vinters H, Cole G, Gylys K. P4-147: Tau Pathology in AD Cortical Synapses: Evidence for Fragmentation and Aggregation Alzheimer's & Dementia. 6: e67-e67. DOI: 10.1016/J.Jalz.2010.08.206 |
0.782 |
|
2010 |
Sokolow S, Luu SH, Vinters HV, Miller CA, Gylys KH. P1-240: Glutamatergic (VGLUT1) synapses are not lost in Alzheimer's disease cerebral cortex, but preferentially accumulate amyloid-beta and p-tau pathology Alzheimer's & Dementia. 6: S243-S243. DOI: 10.1016/J.Jalz.2010.05.791 |
0.524 |
|
2010 |
Gylys KH, Arold SP, Henkins KM, Poon W, Miller CA, Vinters HV, Cole GM. O4-02-01: Apoliprotein-E is increased in Alzheimer's disease synapses and associates with amyloid beta Alzheimer's & Dementia. 6: S152-S152. DOI: 10.1016/J.Jalz.2010.05.473 |
0.76 |
|
2010 |
Ringman JM, Fithian AT, Gylys K, Cummings JL, Coppola G, Pratico D, Moskovitz J, Bitan G. P3-200: Methionine sulfoxide, an index of oxidative stress, measured in plasma of persons with familial Alzheimer's disease mutations Alzheimer's & Dementia. 6: S509-S509. DOI: 10.1016/J.Jalz.2010.05.1698 |
0.329 |
|
2009 |
Gylys KH, Henkins K, Rhoades C, Sokolow S, Vinters HV, Miller CA, Cole GM. O2-06-03: A 56kD SDS-stable peptide assembly is prominent among multiple oligomers in Alzheimer synapses Alzheimer's & Dementia. 5: P115-P116. DOI: 10.1016/J.Jalz.2009.05.363 |
0.752 |
|
2009 |
Sokolow S, Headley AJ, Henkins KM, Miller CA, Vinters HV, Frautschy SA, Cole GM, Gylys KH. P2-130: Increased expression of sodium-calcium exchanger 3 (NCX3) in amyloid-beta positive synaptosomes Alzheimer's & Dementia. 5: P299-P299. DOI: 10.1016/J.Jalz.2009.04.441 |
0.724 |
|
2008 |
Ringman JM, Younkin SG, Pratico D, Seltzer W, Cole GM, Geschwind DH, Rodriguez-Agudelo Y, Schaffer B, Fein J, Sokolow S, Rosario ER, Gylys KH, Varpetian A, Medina LD, Cummings JL. Biochemical markers in persons with preclinical familial Alzheimer disease. Neurology. 71: 85-92. PMID 18509095 DOI: 10.1212/01.Wnl.0000303973.71803.81 |
0.388 |
|
2008 |
Fein JA, Sokolow S, Miller CA, Vinters HV, Yang F, Cole GM, Gylys KH. Co-localization of amyloid beta and tau pathology in Alzheimer's disease synaptosomes. The American Journal of Pathology. 172: 1683-92. PMID 18467692 DOI: 10.2353/Ajpath.2008.070829 |
0.566 |
|
2007 |
Gylys KH, Fein JA, Yang F, Miller CA, Cole GM. Increased cholesterol in Abeta-positive nerve terminals from Alzheimer's disease cortex. Neurobiology of Aging. 28: 8-17. PMID 16332401 DOI: 10.1016/J.Neurobiolaging.2005.10.018 |
0.559 |
|
2004 |
Gylys KH, Fein JA, Yang F, Wiley DJ, Miller CA, Cole GM. Synaptic changes in Alzheimer's disease: increased amyloid-beta and gliosis in surviving terminals is accompanied by decreased PSD-95 fluorescence. The American Journal of Pathology. 165: 1809-17. PMID 15509549 DOI: 10.1016/S0002-9440(10)63436-0 |
0.514 |
|
2003 |
Gylys KH, Fein JA, Tan AM, Cole GM. Apolipoprotein E enhances uptake of soluble but not aggregated amyloid-beta protein into synaptic terminals. Journal of Neurochemistry. 84: 1442-51. PMID 12614344 DOI: 10.1046/j.1471-4159.2003.01643.x |
0.432 |
|
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