| Year |
Citation |
Score |
| 2021 |
Knoke K, Rongisch RR, Grzes KM, Schwarz R, Lorenz B, Yogev N, Pearce EL, Pearce EJ, Kofler DM, Fabri M. Tofacitinib suppresses IL-10/IL-10R signaling and modulates host defense responses in human macrophages. The Journal of Investigative Dermatology. PMID 34536483 DOI: 10.1016/j.jid.2021.07.180 |
0.324 |
|
| 2021 |
Stanczak MA, Sanin DE, Apostolova P, Nerz G, Lampaki D, Hofmann M, Steinmann D, Krohn-Grimberghe M, Thimme R, Mittler G, Waller CF, Pearce EJ, Pearce EL. IL-33 expression in response to SARS-CoV-2 correlates with seropositivity in COVID-19 convalescent individuals. Nature Communications. 12: 2133. PMID 33837219 DOI: 10.1038/s41467-021-22449-w |
0.353 |
|
| 2020 |
Montes de Oca M, de Labastida Rivera F, Winterford C, Frame TCM, Ng SS, Amante FH, Edwards CL, Bukali L, Wang Y, Uzonna JE, Kuns RD, Zhang P, Kabat A, Klein Geltink RI, Pearce EJ, et al. IL-27 signalling regulates glycolysis in Th1 cells to limit immunopathology during infection. Plos Pathogens. 16: e1008994. PMID 33049000 DOI: 10.1371/journal.ppat.1008994 |
0.406 |
|
| 2015 |
Everts B, Tussiwand R, Dreesen L, Fairfax KC, Huang SC, Smith AM, O'Neill CM, Lam WY, Edelson BT, Urban JF, Murphy KM, Pearce EJ. Migratory CD103+ dendritic cells suppress helminth-driven type 2 immunity through constitutive expression of IL-12. The Journal of Experimental Medicine. PMID 26712805 DOI: 10.1084/Jem.20150235 |
0.39 |
|
| 2014 |
Reese TA, Wakeman BS, Choi HS, Hufford MM, Huang SC, Zhang X, Buck MD, Jezewski A, Kambal A, Liu CY, Goel G, Murray PJ, Xavier RJ, Kaplan MH, Renne R, ... ... Pearce EJ, et al. Coinfection. Helminth infection reactivates latent γ-herpesvirus via cytokine competition at a viral promoter. Science (New York, N.Y.). 345: 573-7. PMID 24968940 DOI: 10.1126/Science.1254517 |
0.357 |
|
| 2012 |
Perona-Wright G, Kohlmeier JE, Bassity E, Freitas TC, Mohrs K, Cookenham T, Situ H, Pearce EJ, Woodland DL, Mohrs M. Persistent loss of IL-27 responsiveness in CD8+ memory T cells abrogates IL-10 expression in a recall response. Proceedings of the National Academy of Sciences of the United States of America. 109: 18535-40. PMID 23091017 DOI: 10.1073/pnas.1119133109 |
0.35 |
|
| 2012 |
Pearce EJ, Caspar P, Grzych JM, Lewis FA, Sher A. Pillars article: downregulation of Th1 cytokine production accompanies induction of Th2 responses by a parasitic helminth, Schistosoma mansoni. J. Exp. Med. 1991. 173: 159-166. Journal of Immunology (Baltimore, Md. : 1950). 189: 1104-11. PMID 22815380 |
0.392 |
|
| 2012 |
Fairfax KC, Amiel E, King IL, Freitas TC, Mohrs M, Pearce EJ. IL-10R blockade during chronic schistosomiasis mansoni results in the loss of B cells from the liver and the development of severe pulmonary disease. Plos Pathogens. 8: e1002490. PMID 22291593 DOI: 10.1371/journal.ppat.1002490 |
0.363 |
|
| 2009 |
O'Connell AE, Kerepesi LA, Vandergrift GL, Herbert DR, VAN Winkle TJ, Hooper DC, Pearce EJ, Abraham D. IL-4(-/-) mice with lethal Mesocestoides corti infections--reduced Th2 cytokines and alternatively activated macrophages. Parasite Immunology. 31: 741-9. PMID 19891612 DOI: 10.1111/j.1365-3024.2009.01151.x |
0.402 |
|
| 2009 |
Glatman Zaretsky A, Taylor JJ, King IL, Marshall FA, Mohrs M, Pearce EJ. T follicular helper cells differentiate from Th2 cells in response to helminth antigens. The Journal of Experimental Medicine. 206: 991-9. PMID 19380637 DOI: 10.1084/jem.20090303 |
0.344 |
|
| 2009 |
Taylor JJ, Krawczyk CM, Mohrs M, Pearce EJ. Th2 cell hyporesponsiveness during chronic murine schistosomiasis is cell intrinsic and linked to GRAIL expression. The Journal of Clinical Investigation. 119: 1019-28. PMID 19258704 DOI: 10.1172/JCI36534 |
0.318 |
|
| 2008 |
Marshall FA, Pearce EJ. Uncoupling of induced protein processing from maturation in dendritic cells exposed to a highly antigenic preparation from a helminth parasite. Journal of Immunology (Baltimore, Md. : 1950). 181: 7562-70. PMID 19017945 |
0.307 |
|
| 2008 |
Perona-Wright G, Mohrs K, Taylor J, Zaph C, Artis D, Pearce EJ, Mohrs M. Cutting edge: Helminth infection induces IgE in the absence of mu- or delta-chain expression. Journal of Immunology (Baltimore, Md. : 1950). 181: 6697-701. PMID 18981085 DOI: 10.4049/Jimmunol.181.10.6697 |
0.369 |
|
| 2007 |
Schramm G, Mohrs K, Wodrich M, Doenhoff MJ, Pearce EJ, Haas H, Mohrs M. Cutting edge: IPSE/alpha-1, a glycoprotein from Schistosoma mansoni eggs, induces IgE-dependent, antigen-independent IL-4 production by murine basophils in vivo. Journal of Immunology (Baltimore, Md. : 1950). 178: 6023-7. PMID 17475824 DOI: 10.4049/Jimmunol.178.10.6023 |
0.35 |
|
| 2007 |
Freitas TC, Jung E, Pearce EJ. TGF-beta signaling controls embryo development in the parasitic flatworm Schistosoma mansoni. Plos Pathogens. 3: e52. PMID 17411340 DOI: 10.1371/journal.ppat.0030052 |
0.322 |
|
| 2007 |
Perrigoue JG, Li J, Zaph C, Goldschmidt M, Scott P, de Sauvage FJ, Pearce EJ, Ghilardi N, Artis D. IL-31-IL-31R interactions negatively regulate type 2 inflammation in the lung. The Journal of Experimental Medicine. 204: 481-7. PMID 17353366 DOI: 10.1084/Jem.20061791 |
0.389 |
|
| 2007 |
Sun J, Pearce EJ. Suppression of early IL-4 production underlies the failure of CD4 T cells activated by TLR-stimulated dendritic cells to differentiate into Th2 cells. Journal of Immunology (Baltimore, Md. : 1950). 178: 1635-44. PMID 17237413 |
0.322 |
|
| 2006 |
Perona-Wright G, Jenkins SJ, Crawford A, Gray D, Pearce EJ, MacDonald AS. Distinct sources and targets of IL-10 during dendritic cell-driven Th1 and Th2 responses in vivo. European Journal of Immunology. 36: 2367-75. PMID 16917957 DOI: 10.1002/eji.200535722 |
0.314 |
|
| 2006 |
Taylor JJ, Mohrs M, Pearce EJ. Regulatory T cell responses develop in parallel to Th responses and control the magnitude and phenotype of the Th effector population. Journal of Immunology (Baltimore, Md. : 1950). 176: 5839-47. PMID 16670290 |
0.317 |
|
| 2005 |
Artis D, Kane CM, Fiore J, Zaph C, Shapira S, Joyce K, Macdonald A, Hunter C, Scott P, Pearce EJ. Dendritic cell-intrinsic expression of NF-kappa B1 is required to promote optimal Th2 cell differentiation. Journal of Immunology (Baltimore, Md. : 1950). 174: 7154-9. PMID 15905559 DOI: 10.4049/Jimmunol.174.11.7154 |
0.31 |
|
| 2005 |
Sun J, Walsh M, Villarino AV, Cervi L, Hunter CA, Choi Y, Pearce EJ. TLR ligands can activate dendritic cells to provide a MyD88-dependent negative signal for Th2 cell development. Journal of Immunology (Baltimore, Md. : 1950). 174: 742-51. PMID 15634894 DOI: 10.4049/Jimmunol.174.2.742 |
0.353 |
|
| 2004 |
Magalhães A, Miranda DG, Miranda RG, Araújo MI, Jesus AA, Silva A, Santana LB, Pearce E, Carvalho EM, Jesus AR. Cytokine profile associated with human chronic schistosomiasis mansoni. MemóRias Do Instituto Oswaldo Cruz. 99: 21-6. PMID 15486630 DOI: 10.1590/S0074-02762004000900004 |
0.418 |
|
| 2004 |
McKee AS, Pearce EJ. CD25+CD4+ cells contribute to Th2 polarization during helminth infection by suppressing Th1 response development. Journal of Immunology (Baltimore, Md. : 1950). 173: 1224-31. PMID 15240714 |
0.375 |
|
| 2004 |
de Jesus AR, Magalhães A, Miranda DG, Miranda RG, Araújo MI, de Jesus AA, Silva A, Santana LB, Pearce E, Carvalho EM. Association of type 2 cytokines with hepatic fibrosis in human Schistosoma mansoni infection. Infection and Immunity. 72: 3391-7. PMID 15155645 DOI: 10.1128/Iai.72.6.3391-3397.2004 |
0.432 |
|
| 2003 |
Rankin EB, Yu D, Jiang J, Shen H, Pearce EJ, Goldschmidt MH, Levy DE, Golovkina TV, Hunter CA, Thomas-Tikhonenko A. An essential role of Th1 responses and interferon gamma in infection-mediated suppression of neoplastic growth. Cancer Biology & Therapy. 2: 687-93. PMID 14688478 |
0.374 |
|
| 2003 |
Sher A, Pearce E, Kaye P. Shaping the immune response to parasites: role of dendritic cells. Current Opinion in Immunology. 15: 421-9. PMID 12900274 DOI: 10.1016/S0952-7915(03)00072-4 |
0.336 |
|
| 2003 |
Straw AD, MacDonald AS, Denkers EY, Pearce EJ. CD154 plays a central role in regulating dendritic cell activation during infections that induce Th1 or Th2 responses. Journal of Immunology (Baltimore, Md. : 1950). 170: 727-34. PMID 12517934 DOI: 10.4049/Jimmunol.170.2.727 |
0.324 |
|
| 2003 |
La Flamme AC, MacDonald AS, Huxtable CR, Carroll M, Pearce EJ. Lack of C3 affects Th2 response development and the sequelae of chemotherapy in schistosomiasis. Journal of Immunology (Baltimore, Md. : 1950). 170: 470-6. PMID 12496433 |
0.396 |
|
| 2002 |
La Flamme AC, Scott P, Pearce EJ. Schistosomiasis delays lesion resolution during Leishmania major infection by impairing parasite killing by macrophages. Parasite Immunology. 24: 339-45. PMID 12164819 DOI: 10.1046/J.1365-3024.2002.00473.X |
0.355 |
|
| 2002 |
MacDonald AS, Patton EA, La Flamme AC, Araujo MI, Huxtable CR, Bauman B, Pearce EJ. Impaired Th2 development and increased mortality during Schistosoma mansoni infection in the absence of CD40/CD154 interaction. Journal of Immunology (Baltimore, Md. : 1950). 168: 4643-9. PMID 11971013 DOI: 10.4049/Jimmunol.168.9.4643 |
0.7 |
|
| 2002 |
MacDonald AS, Pearce EJ. Cutting edge: polarized Th cell response induction by transferred antigen-pulsed dendritic cells is dependent on IL-4 or IL-12 production by recipient cells. Journal of Immunology (Baltimore, Md. : 1950). 168: 3127-30. PMID 11907061 |
0.326 |
|
| 2002 |
Beall MJ, Pearce EJ. Transforming growth factor-beta and insulin-like signalling pathways in parasitic helminths. International Journal For Parasitology. 32: 399-404. PMID 11849636 DOI: 10.1016/S0020-7519(01)00348-4 |
0.592 |
|
| 2002 |
McGonigle S, Beall MJ, Pearce EJ. Eukaryotic initiation factor 2 alpha subunit associates with TGF beta receptors and 14-3-3 epsilon and acts as a modulator of the TGF beta response. Biochemistry. 41: 579-87. PMID 11781097 DOI: 10.1021/Bi011407Z |
0.601 |
|
| 2002 |
Patton EA, La Flamme AC, Pedras-Vasoncelos JA, Pearce EJ. Central role for interleukin-4 in regulating nitric oxide-mediated inhibition of T-cell proliferation and gamma interferon production in schistosomiasis. Infection and Immunity. 70: 177-84. PMID 11748180 DOI: 10.1128/Iai.70.1.177-184.2002 |
0.745 |
|
| 2001 |
Hesse M, Modolell M, La Flamme AC, Schito M, Fuentes JM, Cheever AW, Pearce EJ, Wynn TA. Differential regulation of nitric oxide synthase-2 and arginase-1 by type 1/type 2 cytokines in vivo: Granulomatous pathology is shaped by the pattern of L-arginine metabolism Journal of Immunology. 167: 6533-6544. PMID 11714822 DOI: 10.4049/jimmunol.167.11.6533 |
0.378 |
|
| 2001 |
La Flamme AC, Patton EA, Pearce EJ. Role of gamma interferon in the pathogenesis of severe schistosomiasis in interleukin-4-deficient mice. Infection and Immunity. 69: 7445-52. PMID 11705919 DOI: 10.1128/Iai.69.12.7445-7452.2001 |
0.74 |
|
| 2001 |
Beall MJ, Pearce EJ. Human transforming growth factor-beta activates a receptor serine/threonine kinase from the intravascular parasite Schistosoma mansoni. The Journal of Biological Chemistry. 276: 31613-9. PMID 11406634 DOI: 10.1074/Jbc.M104685200 |
0.611 |
|
| 2001 |
McGonigle S, Feeney EL, Beall MJ, Pearce EJ. SIP, a novel SH3 domain-containing protein, interacts with Schistosoma mansoni receptor kinase 1. Molecular and Biochemical Parasitology. 114: 119-23. PMID 11356521 DOI: 10.1016/S0166-6851(01)00232-8 |
0.571 |
|
| 2001 |
Araujo MI, Bliss SK, Suzuki Y, Alcaraz A, Denkers EY, Pearce EJ. Interleukin-12 promotes pathologic liver changes and death in mice coinfected with Schistosoma mansoni and Toxoplasma gondii. Infection and Immunity. 69: 1454-62. PMID 11179312 DOI: 10.1128/Iai.69.3.1454-1462.2001 |
0.418 |
|
| 2001 |
McGonigle S, Beall MJ, Feeney EL, Pearce EJ. Conserved role for 14-3-3epsilon downstream of type I TGFbeta receptors. Febs Letters. 490: 65-9. PMID 11172812 DOI: 10.1016/S0014-5793(01)02133-0 |
0.611 |
|
| 2001 |
La Flamme AC, Patton EA, Bauman B, Pearce EJ. IL-4 plays a crucial role in regulating oxidative damage in the liver during schistosomiasis. Journal of Immunology (Baltimore, Md. : 1950). 166: 1903-11. PMID 11160238 DOI: 10.4049/Jimmunol.166.3.1903 |
0.729 |
|
| 2001 |
Patton EA, Brunet LR, La Flamme AC, Pedras-Vasconcelos J, Kopf M, Pearce EJ. Severe schistosomiasis in the absence of interleukin-4 (IL-4) is IL-12 independent. Infection and Immunity. 69: 589-92. PMID 11119559 DOI: 10.1128/Iai.69.1.589-592.2001 |
0.733 |
|
| 2000 |
Beall MJ, McGonigle S, Pearce EJ. Functional conservation of Schistosoma mansoni Smads in TGF-beta signaling. Molecular and Biochemical Parasitology. 111: 131-42. PMID 11087923 DOI: 10.1016/S0166-6851(00)00307-8 |
0.619 |
|
| 2000 |
Ribeiro de Jesus A, Araújo I, Bacellar O, Magalhães A, Pearce E, Harn D, Strand M, Carvalho EM. Human immune responses to Schistosoma mansoni vaccine candidate antigens. Infection and Immunity. 68: 2797-803. PMID 10768975 DOI: 10.1128/Iai.68.5.2797-2803.2000 |
0.408 |
|
| 2000 |
La Flamme AC, MacDonald AS, Pearce EJ. Role of IL-6 in directing the initial immune response to schistosome eggs. Journal of Immunology (Baltimore, Md. : 1950). 164: 2419-26. PMID 10679078 DOI: 10.4049/jimmunol.164.5.2419 |
0.354 |
|
| 1999 |
Brunet LR, Kopf MA, Pearce EJ. Schistosoma mansoni: IL-4 Is Necessary for Concomitant Immunity in Mice The Journal of Parasitology. 85: 734. DOI: 10.2307/3285752 |
0.358 |
|
| 1999 |
Rosa Brunet L, Sabin EA, Cheever AW, Kopf MA, Pearce EJ. Interleukin 5 (IL-5) Is Not Required for Expression of a Th2 Response or Host Resistance Mechanisms during Murine Schistosomiasis Mansoni but Does Play a Role in Development of IL-4-Producing Non-T, Non-B Cells Infection and Immunity. 67: 3014-3018. DOI: 10.1128/iai.67.6.3014-3018.1999 |
0.39 |
|
| 1996 |
Pearce EJ, Vasconcelos JP, Brunet LR, Sabin EA. IL-4 in schistosomiasis. Experimental Parasitology. 84: 295-9. PMID 8932780 DOI: 10.1006/expr.1996.0116 |
0.362 |
|
| 1996 |
Sabin EA, Kopf MA, Pearce EJ. Schistosoma mansoni egg-induced early IL-4 production is dependent upon IL-5 and eosinophils. The Journal of Experimental Medicine. 184: 1871-8. PMID 8920874 DOI: 10.1084/jem.184.5.1871 |
0.347 |
|
| 1996 |
Pearce EJ, Cheever A, Leonard S, Covalesky M, Fernandez-Botran R, Kohler G, Kopf M. Schistosoma mansoni in IL-4-deficient mice. International Immunology. 8: 435-44. PMID 8671630 DOI: 10.1093/Intimm/8.4.435 |
0.387 |
|
| 1996 |
Araújo MI, Jesus ARd, Bacellar O, Sabin E, Pearce E, Carvalho EM. Evidence of a T helper type 2 activation in human schistosomiasis. European Journal of Immunology. 26: 1399-1403. PMID 8647223 DOI: 10.1002/Eji.1830260633 |
0.438 |
|
| 1996 |
Sabin EA, Araujo MI, Carvalho EM, Pearce EJ. Impairment of tetanus toxoid-specific Th1-like immune responses in humans infected with Schistosoma mansoni. The Journal of Infectious Diseases. 173: 269-72. PMID 8537675 DOI: 10.1093/infdis/173.1.269 |
0.334 |
|
| 1995 |
Sabin EA, Pearce EJ. Early IL-4 production by non-CD4+ cells at the site of antigen deposition predicts the development of a T helper 2 cell response to Schistosoma mansoni eggs Journal of Immunology. 155: 4844-4853. PMID 7594487 |
0.382 |
|
| 1994 |
Vella AT, Pearce EJ. Schistosoma mansoni egg-primed Th0 and Th2 cells: failure to down-regulate IFN-gamma production following in vitro culture. Scandinavian Journal of Immunology. 39: 12-8. PMID 7904772 DOI: 10.1111/j.1365-3083.1994.tb03333.x |
0.301 |
|
| 1992 |
Sher A, Gazzinelli RT, Oswald IP, Clerici M, Kullberg M, Pearce EJ, Berzofsky JA, Mosmann TR, James SL, Morse HC, Shearer GM. Role of T-cell derived cytokines in the downregulation of immune responses in parasitic and retroviral infection Immunological Reviews. 183-204. PMID 1354651 DOI: 10.1111/J.1600-065X.1992.Tb01414.X |
0.442 |
|
| 1992 |
Pearce E, Appleton J. Production of immunomodulatory neuropeptides by Schistosoma mansoni Parasitology Today. 8: 353-354. DOI: 10.1016/0169-4758(92)90161-T |
0.463 |
|
| 1991 |
Finkelman FD, Pearce EJ, Urban JF, Sher A. Regulation and biological function of helminth-induced cytokine responses Immunology Today. 12. PMID 1829892 DOI: 10.1016/S0167-5699(05)80018-0 |
0.399 |
|
| 1991 |
Pearce EJ, Caspar P, Grzych JM, Lewis FA, Sher A. Downregulation of Th1 cytokine production accompanies induction of Th2 responses by a parasitic helminth, Schistosoma mansoni. The Journal of Experimental Medicine. 173: 159-66. PMID 1824635 DOI: 10.1084/Jem.173.1.159 |
0.394 |
|
| 1991 |
Xu YH, Macedonia J, Sher A, Pearce E, Cheever AW. Dynamic analysis of splenic Th1 and Th2 lymphocyte functions in mice infected with Schistosoma japonicum. Infection and Immunity. 59: 2934-40. PMID 1679041 DOI: 10.1128/Iai.59.9.2934-2940.1991 |
0.506 |
|
| 1991 |
Finkelman FD, Pearce EJ, Urban JF, Sher A. Regulation and biological function of helminth-induced cytokine responses Parasitology Today. 7: 62-66. DOI: 10.1016/0169-4758(91)90035-M |
0.377 |
|
| 1990 |
Scott P, Pearce E, Cheever AW, Coffman RL, Sher A. Role of cytokines and CD4+ T-cell subsets in the regulation of parasite immunity and disease. Immunological Reviews. 112: 161-82. PMID 2575073 DOI: 10.1111/J.1600-065X.1989.Tb00557.X |
0.462 |
|
| 1988 |
Scott P, Natovitz P, Coffman RL, Pearce E, Sher A. Immunoregulation of cutaneous leishmaniasis. T cell lines that transfer protective immunity or exacerbation belong to different T helper subsets and respond to distinct parasite antigens. The Journal of Experimental Medicine. 168: 1675-84. PMID 2903212 DOI: 10.1084/Jem.168.5.1675 |
0.415 |
|
| 1987 |
Scott P, Pearce E, Heath S, Sher A. Identification of T-cell-reactive antigens that protect BALB/c mice against Leishmania major. Annales De L'Institut Pasteur. Immunologie. 138: 771-774. PMID 3501959 DOI: 10.1016/S0769-2625(87)80036-3 |
0.322 |
|
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