Lynda A. Morrison - Publications

Affiliations: 
Saint Louis University, St. Louis, MO, United States 
Area:
Microbiology Biology

77 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2023 Korom M, Wang H, Bernier KM, Geiss BJ, Morrison LA. ICP8-vhs- HSV-2 Vaccine Expressing B7 Costimulation Molecules Optimizes Safety and Efficacy against HSV-2 Infection in Mice. Viruses. 15. PMID 37515256 DOI: 10.3390/v15071570  0.729
2023 Gazquez Casals A, Berkowitz AJ, Yu AJ, Waters HE, Schiavone DV, Kapkayeva DM, Morrison LA, Murelli RP. Antiviral activity of amide-appended α-hydroxytropolones against herpes simplex virus-1 and -2. Rsc Advances. 13: 8743-8752. PMID 36936842 DOI: 10.1039/d2ra06749h  0.33
2022 Wang H, Davido DJ, Mostafa HH, Morrison LA. Efficacy of an HSV-1 Neuro-Attenuated Vaccine in Mice Is Reduced by Preventing Viral DNA Replication. Viruses. 14. PMID 35632611 DOI: 10.3390/v14050869  0.354
2020 Lanave G, Martella V, Tempesta M, Catella C, Murelli RP, Morrison LA, Lucente MS, Buonavoglia C, Camero M. Antiviral activity of Α-hydroxytropolones on caprine alphaherpesvirus 1 in vitro. Research in Veterinary Science. 129: 99-102. PMID 31954321 DOI: 10.1016/J.Rvsc.2020.01.011  0.397
2019 Agyemang NB, Kukla CR, Edwards TC, Li Q, Langen MK, Schaal A, Franson AD, Casals AG, Donald KA, Yu AJ, Donlin MJ, Morrison LA, Tavis JE, Murelli RP. Divergent synthesis of a thiolate-based α-hydroxytropolone library with a dynamic bioactivity profile. Rsc Advances. 9: 34227-34234. PMID 33042521 DOI: 10.1039/C9Ra06383H  0.343
2019 Berkowitz AJ, Franson AD, Gazquez Cassals A, Donald KA, Yu AJ, Garimallaprabhakaran AK, Morrison LA, Murelli RP. Importance of lipophilicity for potent anti-herpes simplex virus-1 activity of α-hydroxytropolones. Medchemcomm. 10: 1173-1176. PMID 31391890 DOI: 10.1039/C9Md00225A  0.398
2019 Blevins TP, Yu Y, Belshe RB, Bellamy AR, Morrison LA. Correlation between herpes simplex virus neutralizing antibody titers determined by ELVIS cell and traditional plaque reduction assays. Plos One. 14: e0214467. PMID 30946751 DOI: 10.1371/Journal.Pone.0214467  0.394
2019 Rowe KL, Minaya MA, Belshe RB, Morrison LA. Molecular analyses and phylogeny of the herpes simplex virus 2 US9 and glycoproteins gE/gI obtained from infected subjects during the Herpevac Trial for Women. Plos One. 14: e0212877. PMID 30849089 DOI: 10.1371/Journal.Pone.0212877  0.424
2018 Davido DJ, Tu EM, Wang H, Korom M, Gazquez Casals A, Reddy PJ, Mostafa HH, Combs B, Haenchen SD, Morrison LA. Attenuated HSV-1 expressing a mutant form of ICP6 stimulates a strong immune response that protects mice against HSV-1-induced corneal disease. Journal of Virology. PMID 29950407 DOI: 10.1128/Jvi.01036-18  0.524
2018 Bernier KM, Morrison LA. Antifungal drug ciclopirox olamine reduces HSV-1 replication and disease in mice. Antiviral Research. PMID 29908958 DOI: 10.1016/J.Antiviral.2018.06.010  0.481
2018 Dehghanpir SD, Birkenheuer CH, Yang K, Murelli RP, Morrison LA, Le Grice SFJ, Baines JD. Broad anti-herpesviral activity of α-hydroxytropolones. Veterinary Microbiology. 214: 125-131. PMID 29408023 DOI: 10.1016/J.Vetmic.2017.12.016  0.376
2018 Mostafa HH, Thompson TW, Konen AJ, Haenchen SD, Hilliard JG, Macdonald SJ, Morrison LA, Davido DJ. Herpes Simplex Virus 1 Mutant with Point Mutations in UL39 Is Impaired for Acute Viral Replication in Mice, Establishment of Latency, and Explant-Induced Reactivation. Journal of Virology. PMID 29321311 DOI: 10.1128/Jvi.01654-17  0.526
2017 Hirsch DR, Schiavone DV, Berkowitz AJ, Morrison LA, Masaoka T, Wilson JA, Lomonosova E, Zhao H, Patel BS, Datla SH, Hoft SG, Majidi SJ, Pal RK, Gallicchio E, Tang L, et al. Synthesis and biological assessment of 3,7-dihydroxytropolones. Organic & Biomolecular Chemistry. PMID 29098212 DOI: 10.1039/C7Ob02453C  0.383
2017 Minaya MA, Jensen T, Goll J, Korom M, Datla SH, Belshe RB, Morrison LA. Molecular evolution of herpes simplex virus 2 complete genomes: Comparison between primary and recurrent infections. Journal of Virology. PMID 28931680 DOI: 10.1128/Jvi.00942-17  0.382
2017 Edwards TC, Lomonosova E, Patel JA, Li Q, Villa JA, Gupta AK, Morrison LA, Bailly F, Cotelle P, Giannakopoulou E, Zoidis G, Tavis JE. Inhibition of hepatitis B virus replication by N-hydroxyisoquinolinediones and related polyoxygenated heterocycles. Antiviral Research. PMID 28450058 DOI: 10.1016/J.Antiviral.2017.04.012  0.356
2017 Minaya MA, Korom M, Wang H, Belshe RB, Morrison LA. The herpevac trial for women: Sequence analysis of glycoproteins from viruses obtained from infected subjects. Plos One. 12: e0176687. PMID 28448558 DOI: 10.1371/Journal.Pone.0176687  0.43
2016 Baccari A, Cooney M, Blevins TP, Morrison LA, Larson S, Skoberne M, Belshe RB, Flechtner JB, Long D. Development of a high-throughput β-Gal-based neutralization assay for quantitation of herpes simplex virus-neutralizing antibodies in human samples. Vaccine. PMID 27265458 DOI: 10.1016/J.Vaccine.2016.05.033  0.315
2016 Ireland PJ, Tavis JE, D'Erasmo MP, Hirsch DR, Murelli RP, Cadiz MM, Patel BS, Gupta AK, Edwards TC, Korom M, Moran EA, Morrison LA. Synthetic α-hydroxytropolones inhibit replication of wild-type and acyclovir-resistant herpes simplex viruses. Antimicrobial Agents and Chemotherapy. PMID 26787704 DOI: 10.1128/Aac.02675-15  0.4
2015 Blevins TP, Mitchell MC, Korom M, Wang H, Yu Y, Morrison LA, Belshe RB. Higher Throughput Quantification of Neutralizing Antibody to Herpes Simplex Viruses. Plos One. 10: e0144738. PMID 26658766 DOI: 10.1371/Journal.Pone.0144738  0.444
2014 Tavis JE, Wang H, Tollefson AE, Ying B, Korom M, Cheng X, Cao F, Davis KL, Wold WS, Morrison LA. Inhibitors of nucleotidyltransferase superfamily enzymes suppress herpes simplex virus replication. Antimicrobial Agents and Chemotherapy. 58: 7451-61. PMID 25267681 DOI: 10.1128/Aac.03875-14  0.441
2014 Davis KL, Korom M, Morrison LA. Herpes simplex virus 2 ICP34.5 confers neurovirulence by regulating the type I interferon response. Virology. 468: 330-9. PMID 25238641 DOI: 10.1016/J.Virol.2014.08.015  0.524
2014 Korom M, Davis KL, Morrison LA. Up to four distinct polypeptides are produced from the γ34.5 open reading frame of herpes simplex virus 2. Journal of Virology. 88: 11284-96. PMID 25031346 DOI: 10.1128/Jvi.01284-14  0.428
2013 Korom M, Wylie KM, Wang H, Davis KL, Sangabathula MS, Delassus GS, Morrison LA. A proautophagic antiviral role for the cellular prion protein identified by infection with a herpes simplex virus 1 ICP34.5 mutant. Journal of Virology. 87: 5882-94. PMID 23487467 DOI: 10.1128/Jvi.02559-12  0.743
2013 Wang H, Davido DJ, Morrison LA. HSV-1 strain McKrae is more neuroinvasive than HSV-1 KOS after corneal or vaginal inoculation in mice. Virus Research. 173: 436-40. PMID 23339898 DOI: 10.1016/J.Virusres.2013.01.001  0.469
2012 Mbong EF, Woodley L, Dunkerley E, Schrimpf JE, Morrison LA, Duffy C. Deletion of the herpes simplex virus 1 UL49 gene results in mRNA and protein translation defects that are complemented by secondary mutations in UL41. Journal of Virology. 86: 12351-61. PMID 22951838 DOI: 10.1128/Jvi.01975-12  0.428
2012 Macdonald SJ, Mostafa HH, Morrison LA, Davido DJ. Genome sequence of herpes simplex virus 1 strain McKrae. Journal of Virology. 86: 9540-1. PMID 22879612 DOI: 10.1128/Jvi.01469-12  0.325
2012 Macdonald SJ, Mostafa HH, Morrison LA, Davido DJ. Genome sequence of herpes simplex virus 1 strain KOS. Journal of Virology. 86: 6371-2. PMID 22570244 DOI: 10.1128/Jvi.00646-12  0.34
2011 Morrison LA, DeLassus GS. Breach of the nuclear lamina during assembly of herpes simplex viruses. Nucleus (Austin, Tex.). 2: 271-6. PMID 21941110 DOI: 10.4161/Nucl.2.4.16334  0.453
2011 Schrimpf JE, Tu EM, Wang H, Wong YM, Morrison LA. B7 costimulation molecules encoded by replication-defective, vhs-deficient HSV-1 improve vaccine-induced protection against corneal disease. Plos One. 6: e22772. PMID 21826207 DOI: 10.1371/Journal.Pone.0022772  0.46
2009 Cano-Monreal GL, Wylie KM, Cao F, Tavis JE, Morrison LA. Herpes simplex virus 2 UL13 protein kinase disrupts nuclear lamins. Virology. 392: 137-47. PMID 19640559 DOI: 10.1016/J.Virol.2009.06.051  0.74
2009 Wylie KM, Schrimpf JE, Morrison LA. Increased eIF2alpha phosphorylation attenuates replication of herpes simplex virus 2 vhs mutants in mouse embryonic fibroblasts and correlates with reduced accumulation of the PKR antagonist ICP34.5. Journal of Virology. 83: 9151-62. PMID 19587046 DOI: 10.1128/Jvi.00886-09  0.764
2009 Vagvala SP, Thebeau LG, Wilson SR, Morrison LA. Virus-encoded b7-2 costimulation molecules enhance the protective capacity of a replication-defective herpes simplex virus type 2 vaccine in immunocompetent mice. Journal of Virology. 83: 953-60. PMID 18987142 DOI: 10.1128/Jvi.02022-08  0.554
2008 Morrison LA. Replication-defective virus vaccine-induced protection of mice from genital herpes simplex virus 2 requires CD4 T cells. Virology. 376: 205-10. PMID 18410949 DOI: 10.1016/J.Virol.2008.03.010  0.483
2008 Pasieka TJ, Lu B, Crosby SD, Wylie KM, Morrison LA, Alexander DE, Menachery VD, Leib DA. Herpes simplex virus virion host shutoff attenuates establishment of the antiviral state. Journal of Virology. 82: 5527-35. PMID 18367525 DOI: 10.1128/Jvi.02047-07  0.751
2008 Korom M, Wylie KM, Morrison LA. Selective ablation of virion host shutoff protein RNase activity attenuates herpes simplex virus 2 in mice. Journal of Virology. 82: 3642-53. PMID 18234805 DOI: 10.1128/Jvi.02409-07  0.765
2008 Cano-Monreal GL, Tavis JE, Morrison LA. Substrate specificity of the herpes simplex virus type 2 UL13 protein kinase. Virology. 374: 1-10. PMID 18207213 DOI: 10.1016/J.Virol.2007.11.023  0.733
2008 Thebeau LG, Vagvala SP, Wong YM, Morrison LA. B7 costimulation molecules expressed from the herpes simplex virus 2 genome rescue immune induction in B7-deficient mice (Journal of Virology (2007) 81, 22, (12200-12209)) Journal of Virology. 82: 4685. DOI: 10.1128/JVI.00411-08  0.321
2007 Thebeau LG, Vagvala SP, Wong YM, Morrison LA. B7 costimulation molecules expressed from the herpes simplex virus 2 genome rescue immune induction in B7-deficient mice. Journal of Virology. 81: 12200-9. PMID 17804511 DOI: 10.1128/Jvi.01224-07  0.503
2007 Duerst RJ, Morrison LA. Herpes simplex virus type 2-mediated disease is reduced in mice lacking RNase L. Virology. 360: 322-8. PMID 17157346 DOI: 10.1016/J.Virol.2006.10.042  0.769
2006 Pepose JS, Keadle TL, Morrison LA. Ocular herpes simplex: changing epidemiology, emerging disease patterns, and the potential of vaccine prevention and therapy. American Journal of Ophthalmology. 141: 547-557. PMID 16490506 DOI: 10.1016/J.Ajo.2005.10.008  0.407
2004 Geiss BJ, Cano GL, Tavis JE, Morrison LA. Herpes simplex virus 2 VP22 phosphorylation induced by cellular and viral kinases does not influence intracellular localization. Virology. 330: 74-81. PMID 15527835 DOI: 10.1016/J.Virol.2004.08.034  0.704
2004 Morrison LA. The Toll of herpes simplex virus infection. Trends in Microbiology. 12: 353-6. PMID 15276609 DOI: 10.1016/J.Tim.2004.06.001  0.528
2004 Stuart PM, Summers B, Morris JE, Morrison LA, Leib DA. CD8(+) T cells control corneal disease following ocular infection with herpes simplex virus type 1. The Journal of General Virology. 85: 2055-63. PMID 15218191 DOI: 10.1099/Vir.0.80049-0  0.397
2004 Duerst RJ, Morrison LA. Herpes simplex virus 2 virion host shutoff protein interferes with type I interferon production and responsiveness. Virology. 322: 158-67. PMID 15063125 DOI: 10.1016/J.Virol.2004.01.019  0.789
2003 Duerst RJ, Morrison LA. Innate immunity to herpes simplex virus type 2. Viral Immunology. 16: 475-90. PMID 14733735 DOI: 10.1089/088282403771926300  0.763
2003 Murphy JA, Duerst RJ, Smith TJ, Morrison LA. Herpes simplex virus type 2 virion host shutoff protein regulates alpha/beta interferon but not adaptive immune responses during primary infection in vivo. Journal of Virology. 77: 9337-45. PMID 12915549 DOI: 10.1128/Jvi.77.17.9337-9345.2003  0.781
2003 Thebeau LG, Morrison LA. Mechanism of reduced T-cell effector functions and class-switched antibody responses to herpes simplex virus type 2 in the absence of B7 costimulation. Journal of Virology. 77: 2426-35. PMID 12551980 DOI: 10.1128/Jvi.77.4.2426-2435.2003  0.44
2002 Keadle TL, Laycock KA, Morris JL, Leib DA, Morrison LA, Pepose JS, Stuart PM. Therapeutic vaccination with vhs(-) herpes simplex virus reduces the severity of recurrent herpetic stromal keratitis in mice. The Journal of General Virology. 83: 2361-5. PMID 12237416 DOI: 10.1099/0022-1317-83-10-2361  0.382
2002 Morrison LA. Vaccines against genital herpes: progress and limitations. Drugs. 62: 1119-29. PMID 12010075 DOI: 10.2165/00003495-200262080-00001  0.433
2002 Keadle TL, Morrison LA, Morris JL, Pepose JS, Stuart PM. Therapeutic immunization with a virion host shutoff-defective, replication-incompetent herpes simplex virus type 1 strain limits recurrent herpetic ocular infection. Journal of Virology. 76: 3615-25. PMID 11907201 DOI: 10.1128/Jvi.76.8.3615-3625.2002  0.545
2002 Thebeau LG, Morrison LA. B7 costimulation plays an important role in protection from herpes simplex virus type 2-mediated pathology. Journal of Virology. 76: 2563-6. PMID 11836436 DOI: 10.1128/Jvi.76.5.2563-2566.2002  0.486
2002 Smith TJ, Morrison LA, Leib DA. Pathogenesis of herpes simplex virus type 2 virion host shutoff (vhs) mutants. Journal of Virology. 76: 2054-61. PMID 11836383 DOI: 10.1128/Jvi.76.5.2054-2061.2002  0.58
2001 Geiss BJ, Tavis JE, Metzger LM, Leib DA, Morrison LA. Temporal regulation of herpes simplex virus type 2 VP22 expression and phosphorylation. Journal of Virology. 75: 10721-9. PMID 11602713 DOI: 10.1128/Jvi.75.22.10721-10729.2001  0.764
2001 Da Costa XJ, Morrison LA, Knipe DM. Comparison of different forms of herpes simplex replication-defective mutant viruses as vaccines in a mouse model of HSV-2 genital infection Virology. 288: 256-263. PMID 11601897 DOI: 10.1006/Viro.2001.1094  0.442
2001 Prejean C, Sarma T, Kurnasov O, Usacheva A, Hemmings B, Cantley L, Fruman DA, Morrison LA, Buller RM, Colamonici OR. Phosphatidylinositol 3-kinase confers resistance to encephalomyocarditis and herpes simplex virus-induced cell death through the activation of distinct downstream effectors Journal of Immunology. 167: 4553-4559. PMID 11591783 DOI: 10.4049/Jimmunol.167.8.4553  0.451
2001 Morrison LA, Zhu L, Thebeau LG. Vaccine-induced serum immunoglobin contributes to protection from herpes simplex virus type 2 genital infection in the presence of immune T cells Journal of Virology. 75: 1195-1204. PMID 11152492 DOI: 10.1128/Jvi.75.3.1195-1204.2001  0.556
2000 Geiss BJ, Smith TJ, Leib DA, Morrison LA. Disruption of virion host shutoff activity improves the immunogenicity and protective capacity of a replication-incompetent herpes simplex virus type 1 vaccine strain. Journal of Virology. 74: 11137-44. PMID 11070010 DOI: 10.1128/Jvi.74.23.11137-11144.2000  0.76
2000 Born TL, Morrison LA, Esteban DJ, VandenBos T, Thebeau LG, Chen N, Spriggs MK, Sims JE, Buller RML. A poxvirus protein that binds to and inactivates IL-18, and inhibits NK cell response Journal of Immunology. 164: 3246-3254. PMID 10706717 DOI: 10.4049/Jimmunol.164.6.3246  0.354
1998 Morrison LA, Da Costa XJ, Knipe DM. Influence of mucosal and parenteral immunization with a replication- defective mutant of HSV-2 on immune responses and protection from genital challenge Virology. 243: 178-187. PMID 9527927 DOI: 10.1006/Viro.1998.9047  0.5
1997 Morrison LA, Knipe DM. Contributions of antibody and T cell subsets to protection elicited by immunization with a replication-defective mutant of herpes simplex virus type 1 Virology. 239: 315-326. PMID 9434723 DOI: 10.1006/Viro.1997.8884  0.477
1996 Brubaker JO, Thompson CM, Morrison LA, Knipe DM, Siber GR, Finberg RW. Th1-Associated Immune Responses to β-Galactosidase Expressed by a Replication-Defective Herpes Simplex Virus Journal of Immunology. 157: 1598-1604. PMID 8759744  0.397
1996 Morrison LA, Knipe DM. Mechanisms of immunization with a replication-defective mutant of herpes simplex virus Virology. 220: 402-413. PMID 8661391 DOI: 10.1006/Viro.1996.0328  0.58
1996 Babu JS, Thomas J, Kanangat S, Morrison LA, Knipe DM, Rouse BT. Viral replication is required for induction of ocular immunopathology by herpes simplex virus Journal of Virology. 70: 101-107. PMID 8523513 DOI: 10.1128/Jvi.70.1.101-107.1996  0.592
1994 Morrison LA, Knipe DM. Immunization with replication-defective mutants of herpes simplex virus type 1: Sites of immune intervention in pathogenesis of challenge virus infection Journal of Virology. 68: 689-696. PMID 8289372 DOI: 10.1128/Jvi.68.2.689-696.1994  0.605
1994 Wilson GAR, Morrison LA, Fields BN. Association of the reovirus S1 gene with serotype 3-induced biliary atresia in mice Journal of Virology. 68: 6458-6465. PMID 8083983 DOI: 10.1128/Jvi.68.10.6458-6465.1994  0.394
1993 Morrison LA, Fields BN, Dermody TS. Prolonged replication in the mouse central nervous system of reoviruses isolated from persistently infected cell cultures Journal of Virology. 67: 3019-3026. PMID 8388486 DOI: 10.1128/Jvi.67.6.3019-3026.1993  0.541
1991 Morrison LA, Fields BN. Parallel mechanisms in neuropathogenesis of enteric virus infections Journal of Virology. 65: 2767-2772. PMID 1851851 DOI: 10.1128/Jvi.65.6.2767-2772.1991  0.497
1991 Morrison LA, Sidman RL, Fields BN. Direct spread of reovirus from the intestinal lumen to the central nervous system through vagal autonomic nerve fibers. Proceedings of the National Academy of Sciences of the United States of America. 88: 3852-6. PMID 1850838 DOI: 10.1073/Pnas.88.9.3852  0.431
1991 Flamand A, Gagner JP, Morrison LA, Fields BN. Penetration of the nervous systems of suckling mice by mammalian reoviruses Journal of Virology. 65: 123-131. PMID 1845880 DOI: 10.1128/Jvi.65.1.123-131.1991  0.425
1991 Neutra M, Weltzin R, Winner L, Mack J, Michetti P, Morrison L, Fields BN, Mekalanos JJ, Kraehenbuhl JP. Identification and use of protective monoclonal IgA antibodies against viral and bacterial pathogens. Advances in Experimental Medicine and Biology. 310: 179-82. PMID 1808995 DOI: 10.1007/978-1-4615-3838-7_22  0.316
1991 Morrison LA, Fields BN. Viral pathogenesis and central nervous system infection Seminars in Neuroscience. 3: 83-91. DOI: 10.1016/1044-5765(91)90002-6  0.507
1989 Braciale TJ, Sweetser MT, Morrison LA, Kittlesen DJ, Braciale VL. Class I major histocompatibility complex-restricted cytolytic T lymphocytes recognize a limited number of sites on the influenza hemagglutinin Proceedings of the National Academy of Sciences of the United States of America. 86: 277-281. PMID 2463623 DOI: 10.1073/Pnas.86.1.277  0.379
1988 Morrison LA, Braciale VL, Braciale TJ. Antigen form influences induction and frequency of influenza-specific class I and class II MHC-restricted cytolytic T lymphocytes Journal of Immunology. 141: 363-368. PMID 2454989  0.37
1986 Morrison LA, Lukacher AE, Braciale VL, Fan DP. Differences in antigen presentation to MHC class I- and class II-restricted influenza virus-specific cytolytic T lymphocyte clones Journal of Experimental Medicine. 163: 903-921. PMID 3485173 DOI: 10.1084/Jem.163.4.903  0.412
1986 Morrison LA, Braciale VL, Braciale TJ. Distinguishable pathways of viral antigen presentation to T lymphocytes Immunologic Research. 5: 294-304. PMID 3298467 DOI: 10.1007/Bf02935502  0.338
1985 Lukacher AE, Morrison LA, Braciale VL, Malissen B. Expression of specific cytolytic activity by H-21 region-restricted, influenza virus-specific T lymphocyte clones Journal of Experimental Medicine. 162: 171-187. PMID 2409206 DOI: 10.1084/Jem.162.1.171  0.414
1984 Mertz GJ, Peterman G, Ashley R, Jourden JL, Salter D, Morrison L, McLean A, Corey L. Herpes Simplex Virus Type-2 Glycoprotein-Subunit Vaccine: Tolerance and Humoral and Cellular Responses in Humans The Journal of Infectious Diseases. 150: 242-249. PMID 6088648 DOI: 10.1093/Infdis/150.2.242  0.378
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