Lawrence C. Brody - Publications

Affiliations: 
Nursing University of Utah, Salt Lake City, UT 
Area:
Nursing

121 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2020 Justice CM, Cuellar A, Bala K, Sabourin JA, Cunningham ML, Crawford K, Phipps JM, Zhou Y, Cilliers D, Byren JC, Johnson D, Wall SA, Morton JEV, Noons P, Sweeney E, ... ... Brody L, et al. A genome-wide association study implicates the BMP7 locus as a risk factor for nonsyndromic metopic craniosynostosis. Human Genetics. PMID 32266521 DOI: 10.1007/S00439-020-02157-Z  0.38
2019 Stevelink R, Pangilinan F, Jansen FE, Braun KPJ, Molloy AM, Brody LC, Koeleman BPC. Assessing the genetic association between vitamin B6 metabolism and genetic generalized epilepsy. Molecular Genetics and Metabolism Reports. 21: 100518. PMID 31641590 DOI: 10.1016/J.Ymgmr.2019.100518  0.387
2019 Jenkins MM, Almli LM, Pangilinan F, Chong JX, Blue EE, Shapira SK, White J, McGoldrick D, Smith JD, Mullikin JC, Bean CJ, Nembhard WN, Lou XY, Shaw GM, Romitti PA, ... ... Brody LC, et al. Exome sequencing of family trios from the National Birth Defects Prevention Study: Tapping into a rich resource of genetic and environmental data. Birth Defects Research. PMID 31328417 DOI: 10.1002/Bdr2.1554  0.32
2018 Bai H, Guo X, Narisu N, Lan T, Wu Q, Xing Y, Zhang Y, Bond SR, Pei Z, Zhang Y, Zhang D, Jirimutu J, Zhang D, Yang X, Morigenbatu M, ... ... Brody LC, et al. Whole-genome sequencing of 175 Mongolians uncovers population-specific genetic architecture and gene flow throughout North and East Asia. Nature Genetics. PMID 30397334 DOI: 10.1038/S41588-018-0250-5  0.326
2018 Shane B, Pangilinan F, Mills JL, Fan R, Gong T, Cropp CD, Kim Y, Ueland PM, Bailey-Wilson JE, Wilson AF, Brody LC, Molloy AM. The 677C→T variant of MTHFR is the major genetic modifier of biomarkers of folate status in a young, healthy Irish population. The American Journal of Clinical Nutrition. PMID 30339177 DOI: 10.1093/Ajcn/Nqy209  0.356
2018 Sabourin JA, Cropp CD, Sung H, Brody LC, Bailey-Wilson JE, Wilson AF. ComPaSS-GWAS: A method to reduce type I error in genome-wide association studies when replication data are not available. Genetic Epidemiology. PMID 30334581 DOI: 10.1002/Gepi.22168  0.329
2018 O'Reilly J, Pangilinan F, Hokamp K, Ueland PM, Brosnan JT, Brosnan ME, Brody LC, Molloy AM. The impact of common genetic variants in the mitochondrial glycine cleavage system on relevant metabolites. Molecular Genetics and Metabolism Reports. 16: 20-22. PMID 29988937 DOI: 10.1016/J.Ymgmr.2018.05.006  0.369
2018 Toland AE, Forman A, Couch FJ, Culver JO, Eccles DM, Foulkes WD, Hogervorst FBL, Houdayer C, Levy-Lahad E, Monteiro AN, Neuhausen SL, Plon SE, Sharan SK, Spurdle AB, Szabo C, ... Brody LC, et al. Clinical testing ofand: a worldwide snapshot of technological practices. Npj Genomic Medicine. 3: 7. PMID 29479477 DOI: 10.1038/S41525-018-0046-7  0.324
2017 Gilbert E, O'Reilly S, Merrigan M, McGettigan D, Molloy AM, Brody LC, Bodmer W, Hutnik K, Ennis S, Lawson DJ, Wilson JF, Cavalleri GL. The Irish DNA Atlas: Revealing Fine-Scale Population Structure and History within Ireland. Scientific Reports. 7: 17199. PMID 29222464 DOI: 10.1038/S41598-017-17124-4  0.32
2017 Giannakou A, Sicko RJ, Zhang W, Romitti P, Browne ML, Caggana M, Brody LC, Jelliffe-Pawlowski L, Shaw GM, Kay DM, Mills JL. Copy number variants in Ebstein anomaly. Plos One. 12: e0188168. PMID 29216221 DOI: 10.1371/Journal.Pone.0188168  0.345
2017 Velkova A, Diaz JEL, Pangilinan F, Molloy AM, Mills JL, Shane B, Sanchez E, Cunningham C, McNulty H, Cropp CD, Bailey-Wilson JE, Wilson AF, Brody LC. The FUT2 secretor variant p.Trp154Ter influences serum vitamin B12 concentration via holo-haptocorrin, but not holo-transcobalamin, and is associated with haptocorrin glycosylation. Human Molecular Genetics. PMID 29040465 DOI: 10.1093/Hmg/Ddx369  0.363
2017 Ormond KE, Mortlock DP, Scholes DT, Bombard Y, Brody LC, Faucett WA, Garrison NA, Hercher L, Isasi R, Middleton A, Musunuru K, Shriner D, Virani A, Young CE. Human Germline Genome Editing. American Journal of Human Genetics. 101: 167-176. PMID 28777929 DOI: 10.1016/J.Ajhg.2017.06.012  0.328
2017 Molloy AM, Pangilinan F, Brody LC. Genetic Risk Factors for Folate-Responsive Neural Tube Defects. Annual Review of Nutrition. PMID 28628360 DOI: 10.1146/Annurev-Nutr-071714-034235  0.374
2017 Carter TC, Sicko RJ, Kay DM, Browne ML, Romitti PA, Edmunds ZL, Liu A, Fan R, Druschel CM, Caggana M, Brody LC, Mills JL. Copy-number variants and candidate gene mutations in isolated split hand/foot malformation. Journal of Human Genetics. PMID 28539665 DOI: 10.1038/Jhg.2017.56  0.385
2017 Samimi G, Bernardini MQ, Brody LC, Caga-Anan CF, Campbell IG, Chenevix-Trench G, Couch FJ, Dean M, de Hullu JA, Domchek SM, Drapkin R, Spencer Feigelson H, Friedlander M, Gaudet MM, Harmsen MG, et al. Traceback: A Proposed Framework to Increase Identification and Genetic Counseling of BRCA1 and BRCA2 Mutation Carriers Through Family-Based Outreach. Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. JCO2016703439. PMID 28398847 DOI: 10.1200/Jco.2016.70.3439  0.382
2016 Dimopoulos A, Sicko RJ, Kay DM, Rigler SL, Druschel CM, Caggana M, Browne ML, Fan R, Romitti PA, Brody LC, Mills JL. Rare copy number variants in a population-based investigation of hypoplastic right heart syndrome. Birth Defects Research. Part a, Clinical and Molecular Teratology. PMID 28009100 DOI: 10.1002/Bdra.23586  0.305
2016 Dimopoulos A, Sicko RJ, Kay DM, Rigler SL, Fan R, Romitti PA, Browne ML, Druschel CM, Caggana M, Brody LC, Mills JL. Copy number variants in a population-based investigation of Klippel-Trenaunay syndrome. American Journal of Medical Genetics. Part A. PMID 27901321 DOI: 10.1002/Ajmg.A.37868  0.371
2016 Sicko RJ, Browne ML, Rigler SL, Druschel CM, Liu G, Fan R, Romitti PA, Caggana M, Kay DM, Brody LC, Mills JL. Genetic Variants in Isolated Ebstein Anomaly Implicated in Myocardial Development Pathways. Plos One. 11: e0165174. PMID 27788187 DOI: 10.1371/Journal.Pone.0165174  0.369
2016 Hagen EM, Sicko RJ, Kay DM, Rigler SL, Dimopoulos A, Ahmad S, Doleman MH, Fan R, Romitti PA, Browne ML, Caggana M, Brody LC, Shaw GM, Jelliffe-Pawlowski LL, Mills JL. Copy-number variant analysis of classic heterotaxy highlights the importance of body patterning pathways. Human Genetics. PMID 27637763 DOI: 10.1007/S00439-016-1727-X  0.354
2016 Ozel AB, McGee B, Siemieniak D, Jacobi PM, Haberichter SL, Brody LC, Mills JL, Molloy AM, Ginsburg D, Li JZ, Desch KC. Genome-wide studies of von Willebrand Factor Propeptide Identify Loci Contributing to Variation in Propeptide Levels and von Willebrand Factor Clearance. Journal of Thrombosis and Haemostasis : Jth. PMID 27359253 DOI: 10.1111/Jth.13401  0.366
2016 Molloy AM, Pangilinan F, Mills JL, Shane B, O'Neill MB, McGaughey DM, Velkova A, Abaan HO, Ueland PM, McNulty H, Ward M, Strain JJ, Cunningham C, Casey M, Cropp CD, ... ... Brody LC, et al. A Common Polymorphism in HIBCH Influences Methylmalonic Acid Concentrations in Blood Independently of Cobalamin. American Journal of Human Genetics. PMID 27132595 DOI: 10.1016/J.Ajhg.2016.03.005  0.392
2016 Sobczyńska-Malefora A, Pangilinan F, Plant GT, Velkova A, Harrington DJ, Molloy AM, Brody LC. Association of a transcobalamin II genetic variant with falsely low results for the holotranscobalamin immunoassay. European Journal of Clinical Investigation. PMID 26951924 DOI: 10.1111/Eci.12617  0.337
2016 Szymczak S, Holzinger E, Dasgupta A, Malley JD, Molloy AM, Mills JL, Brody LC, Stambolian D, Bailey-Wilson JE. r2VIM: A new variable selection method for random forests in genome-wide association studies. Biodata Mining. 9: 7. PMID 26839594 DOI: 10.1186/S13040-016-0087-3  0.313
2016 VanderMeer JE, Carter TC, Pangilinan F, Mitchell A, Kurnat-Thoma E, Kirke PN, Troendle JF, Molloy AM, Munger RG, Feldkamp ML, Mansilla MA, Mills JL, Murray JC, Brody LC. Evaluation of proton-coupled folate transporter (SLC46A1) polymorphisms as risk factors for neural tube defects and oral clefts. American Journal of Medical Genetics. Part A. PMID 26789141 DOI: 10.1002/Ajmg.A.37539  0.755
2015 Boghossian NS, Sicko RJ, Kay DM, Rigler SL, Caggana M, Tsai MY, Yeung EH, Pankratz N, Cole BR, Druschel CM, Romitti PA, Browne ML, Fan R, Liu A, Brody LC, et al. Rare copy number variants implicated in posterior urethral valves. American Journal of Medical Genetics. Part A. PMID 26663319 DOI: 10.1002/Ajmg.A.37493  0.387
2015 Ozaki M, Molloy AM, Mills JL, Fan R, Wang Y, Gibney ER, Shane B, Brody LC, Parle-McDermott A. The Dihydrofolate Reductase 19 bp Polymorphism Is Not Associated with Biomarkers of Folate Status in Healthy Young Adults, Irrespective of Folic Acid Intake. The Journal of Nutrition. PMID 26269242 DOI: 10.3945/Jn.115.216101  0.392
2015 Kurnat-Thoma EL, Pangilinan F, Matteini AM, Wong B, Pepper GA, Stabler SP, Guralnik JM, Brody LC. Association of Transcobalamin II (TCN2) and Transcobalamin II-Receptor (TCblR) Genetic Variations With Cobalamin Deficiency Parameters in Elderly Women. Biological Research For Nursing. 17: 444-54. PMID 25657319 DOI: 10.1177/1099800415569506  0.744
2015 Jhuraney A, Velkova A, Johnson RC, Kessing B, Carvalho RS, Whiley P, Spurdle AB, Vreeswijk MP, Caputo SM, Millot GA, Vega A, Coquelle N, Galli A, Eccles D, Blok MJ, ... ... Brody LC, et al. BRCA1 Circos: a visualisation resource for functional analysis of missense variants. Journal of Medical Genetics. 52: 224-30. PMID 25643705 DOI: 10.1136/Jmedgenet-2014-102766  0.37
2015 Rigler SL, Kay DM, Sicko RJ, Fan R, Liu A, Caggana M, Browne ML, Druschel CM, Romitti PA, Brody LC, Mills JL. Novel copy-number variants in a population-based investigation of classic heterotaxy. Genetics in Medicine : Official Journal of the American College of Medical Genetics. 17: 348-57. PMID 25232849 DOI: 10.1038/Gim.2014.112  0.344
2014 Pangilinan F, Molloy AM, Mills JL, Troendle JF, Parle-McDermott A, Kay DM, Browne ML, McGrath EC, Abaan HO, Sutton M, Kirke PN, Caggana M, Shane B, Scott JM, Brody LC. Replication and exploratory analysis of 24 candidate risk polymorphisms for neural tube defects. Bmc Medical Genetics. 15: 102. PMID 25293959 DOI: 10.1186/S12881-014-0102-9  0.441
2014 Mills JL, Fan R, Brody LC, Liu A, Ueland PM, Wang Y, Kirke PN, Shane B, Molloy AM. Maternal choline concentrations during pregnancy and choline-related genetic variants as risk factors for neural tube defects. The American Journal of Clinical Nutrition. 100: 1069-74. PMID 25240073 DOI: 10.3945/Ajcn.113.079319  0.336
2014 Ma Q, Ozel AB, Ramdas S, McGee B, Khoriaty R, Siemieniak D, Li HD, Guan Y, Brody LC, Mills JL, Molloy AM, Ginsburg D, Li JZ, Desch KC. Genetic variants in PLG, LPA, and SIGLEC 14 as well as smoking contribute to plasma plasminogen levels. Blood. 124: 3155-64. PMID 25208887 DOI: 10.1182/Blood-2014-03-560086  0.393
2014 Anney RJL, Avbersek A, Balding D, Baum L, Becker F, Berkovic SF, Bradfi JP, Brody LC, Buono RJ, Catarino CB, Cavalleri GL, Cherny SS, Chinthapalli K, Coffey AJ, Compston A, et al. Genetic determinants of common epilepsies: A meta-analysis of genome-wide association studies The Lancet Neurology. 13: 893-903. PMID 25087078 DOI: 10.1016/S1474-4422(14)70171-1  0.318
2014 Molloy AM, Einri CN, Jain D, Laird E, Fan R, Wang Y, Scott JM, Shane B, Brody LC, Kirke PN, Mills JL. Is low iron status a risk factor for neural tube defects? Birth Defects Research. Part a, Clinical and Molecular Teratology. 100: 100-6. PMID 24535840 DOI: 10.1002/Bdra.23223  0.323
2013 Mamasoula C, Prentice RR, Pierscionek T, Pangilinan F, Mills JL, Druschel C, Pass K, Russell MW, Hall D, Töpf A, Brown DL, Zelenika D, Bentham J, Cosgrove C, Bhattacharya S, ... ... Brody LC, et al. Association between C677T polymorphism of methylene tetrahydrofolate reductase and congenital heart disease: meta-analysis of 7697 cases and 13,125 controls. Circulation. Cardiovascular Genetics. 6: 347-53. PMID 23876493 DOI: 10.1161/Circgenetics.113.000191  0.309
2013 Desch KC, Ozel AB, Siemieniak D, Kalish Y, Shavit JA, Thornburg CD, Sharathkumar AA, McHugh CP, Laurie CC, Crenshaw A, Mirel DB, Kim Y, Cropp CD, Molloy AM, Kirke PN, ... ... Brody LC, et al. Linkage analysis identifies a locus for plasma von Willebrand factor undetected by genome-wide association. Proceedings of the National Academy of Sciences of the United States of America. 110: 588-93. PMID 23267103 DOI: 10.1073/Pnas.1219885110  0.363
2013 Carter TC, Kay DM, Browne ML, Liu A, Romitti PA, Kuehn D, Conley MR, Caggana M, Druschel CM, Brody LC, Mills JL. Anorectal atresia and variants at predicted regulatory sites in candidate genes. Annals of Human Genetics. 77: 31-46. PMID 23127126 DOI: 10.1111/J.1469-1809.2012.00734.X  0.371
2013 Hinckley J, Burns T, Wang K, Ozel AB, Heiman M, Shapiro A, Montgomery RR, Brody L, Desch KC, Di Paola J. SNP Analysis Of The VWF GENE Identifies Multiple Common Variants THAT Affect VWF Levels and OCCUR At Different Frequencies In Patients With TYPE 1 VWD Blood. 122: 334-334. DOI: 10.1182/Blood.V122.21.334.334  0.405
2012 Browne ML, Carter TC, Kay DM, Kuehn D, Brody LC, Romitti PA, Liu A, Caggana M, Druschel CM, Mills JL. Evaluation of genes involved in limb development, angiogenesis, and coagulation as risk factors for congenital limb deficiencies. American Journal of Medical Genetics. Part A. 158: 2463-72. PMID 22965740 DOI: 10.1002/Ajmg.A.35565  0.417
2012 Pangilinan F, Molloy AM, Mills JL, Troendle JF, Parle-McDermott A, Signore C, O'Leary VB, Chines P, Seay JM, Geiler-Samerotte K, Mitchell A, VanderMeer JE, Krebs KM, Sanchez A, Cornman-Homonoff J, ... ... Brody LC, et al. Evaluation of common genetic variants in 82 candidate genes as risk factors for neural tube defects. Bmc Medical Genetics. 13: 62. PMID 22856873 DOI: 10.1186/1471-2350-13-62  0.421
2012 Carter TC, Kay DM, Browne ML, Liu A, Romitti PA, Kuehn D, Conley MR, Caggana M, Druschel CM, Brody LC, Mills JL. Hirschsprung's disease and variants in genes that regulate enteric neural crest cell proliferation, migration and differentiation. Journal of Human Genetics. 57: 485-93. PMID 22648184 DOI: 10.1038/Jhg.2012.54  0.401
2012 Reid RJ, McBride CM, Alford SH, Price C, Baxevanis AD, Brody LC, Larson EB. Association between health-service use and multiplex genetic testing. Genetics in Medicine : Official Journal of the American College of Medical Genetics. 14: 852-9. PMID 22595941 DOI: 10.1038/Gim.2012.52  0.316
2012 Minguzzi S, Molloy AM, Peadar K, Mills J, Scott JM, Troendle J, Pangilinan F, Brody L, Parle-McDermott A. Genotyping of a tri-allelic polymorphism by a novel melting curve assay in MTHFD1L: an association study of nonsyndromic Cleft in Ireland. Bmc Medical Genetics. 13: 29. PMID 22520921 DOI: 10.1186/1471-2350-13-29  0.419
2012 Kaphingst KA, McBride CM, Wade C, Alford SH, Reid R, Larson E, Baxevanis AD, Brody LC. Patients' understanding of and responses to multiplex genetic susceptibility test results. Genetics in Medicine : Official Journal of the American College of Medical Genetics. 14: 681-7. PMID 22481132 DOI: 10.1038/Gim.2012.22  0.331
2012 Cabral WA, Barnes AM, Adeyemo A, Cushing K, Chitayat D, Porter FD, Panny SR, Gulamali-Majid F, Tishkoff SA, Rebbeck TR, Gueye SM, Bailey-Wilson JE, Brody LC, Rotimi CN, Marini JC. A founder mutation in LEPRE1 carried by 1.5% of West Africans and 0.4% of African Americans causes lethal recessive osteogenesis imperfecta. Genetics in Medicine : Official Journal of the American College of Medical Genetics. 14: 543-51. PMID 22281939 DOI: 10.1038/Gim.2011.44  0.351
2012 Mills JL, Carter TC, Kay DM, Browne ML, Brody LC, Liu A, Romitti PA, Caggana M, Druschel CM. Folate and vitamin B12-related genes and risk for omphalocele. Human Genetics. 131: 739-46. PMID 22116453 DOI: 10.1007/S00439-011-1117-3  0.423
2011 Stone N, Pangilinan F, Molloy AM, Shane B, Scott JM, Ueland PM, Mills JL, Kirke PN, Sethupathy P, Brody LC. Bioinformatic and genetic association analysis of microRNA target sites in one-carbon metabolism genes. Plos One. 6: e21851. PMID 21765920 DOI: 10.1371/Journal.Pone.0021851  0.306
2011 Biswas K, Das R, Alter BP, Kuznetsov SG, Stauffer S, North SL, Burkett S, Brody LC, Meyer S, Byrd RA, Sharan SK. A comprehensive functional characterization of BRCA2 variants associated with Fanconi anemia using mouse ES cell-based assay. Blood. 118: 2430-42. PMID 21719596 DOI: 10.1182/Blood-2010-12-324541  0.378
2011 Carter TC, Pangilinan F, Troendle JF, Molloy AM, VanderMeer J, Mitchell A, Kirke PN, Conley MR, Shane B, Scott JM, Brody LC, Mills JL. Evaluation of 64 candidate single nucleotide polymorphisms as risk factors for neural tube defects in a large Irish study population. American Journal of Medical Genetics. Part A. 155: 14-21. PMID 21204206 DOI: 10.1002/Ajmg.A.33755  0.451
2010 Pangilinan F, Mitchell A, VanderMeer J, Molloy AM, Troendle J, Conley M, Kirke PN, Sutton M, Sequeira JM, Quadros EV, Scott JM, Mills JL, Brody LC. Transcobalamin II receptor polymorphisms are associated with increased risk for neural tube defects. Journal of Medical Genetics. 47: 677-85. PMID 20577008 DOI: 10.1136/Jmg.2009.073775  0.363
2010 Wong HL, Peters U, Hayes RB, Huang WY, Schatzkin A, Bresalier RS, Velie EM, Brody LC. Polymorphisms in the adenomatous polyposis coli (APC) gene and advanced colorectal adenoma risk. European Journal of Cancer (Oxford, England : 1990). 46: 2457-66. PMID 20510605 DOI: 10.1016/J.Ejca.2010.04.020  0.427
2010 Beaty TH, Murray JC, Marazita ML, Munger RG, Ruczinski I, Hetmanski JB, Liang KY, Wu T, Murray T, Fallin MD, Redett RA, Raymond G, Schwender H, Jin SC, Cooper ME, ... ... Brody L, et al. A genome-wide association study of cleft lip with and without cleft palate identifies risk variants near MAFB and ABCA4. Nature Genetics. 42: 525-9. PMID 20436469 DOI: 10.1038/Ng.580  0.401
2010 Carter TC, Molloy AM, Pangilinan F, Troendle JF, Kirke PN, Conley MR, Orr DJ, Earley M, McKiernan E, Lynn EC, Doyle A, Scott JM, Brody LC, Mills JL. Testing reported associations of genetic risk factors for oral clefts in a large Irish study population. Birth Defects Research. Part a, Clinical and Molecular Teratology. 88: 84-93. PMID 19937600 DOI: 10.1002/Bdra.20639  0.393
2010 Wade CH, McBride CM, Kardia SL, Brody LC. Considerations for designing a prototype genetic test for use in translational research. Public Health Genomics. 13: 155-65. PMID 19729884 DOI: 10.1159/000236061  0.326
2010 Wade CH, McBride CM, Kardia SLR, Brody LC. A response to 'Why realistic test scenarios in translational research remain hypothetical' Public Health Genomics. 13: 169-170. DOI: 10.1159/000236063  0.346
2010 Beaty TH, Murray JC, Marazita ML, Munger RG, Hetmanski IRJB, Liang KY, Wu T, Murray T, Fallin MD, Redett RA, Raymond G, Schwender H, Jin SC, Cooper ME, Dunnwald M, ... ... Brody L, et al. Erratum: A genome-wide association study of cleft lip with and without cleft palate identifies risk variants near MAFB and ABCA4 Nature Genetics. 42: 727-727. DOI: 10.1038/Ng0810-727  0.359
2009 Parle-McDermott A, Pangilinan F, O'Brien KK, Mills JL, Magee AM, Troendle J, Sutton M, Scott JM, Kirke PN, Molloy AM, Brody LC. A common variant in MTHFD1L is associated with neural tube defects and mRNA splicing efficiency. Human Mutation. 30: 1650-6. PMID 19777576 DOI: 10.1002/Humu.21109  0.456
2009 McBride CM, Alford SH, Reid RJ, Larson EB, Baxevanis AD, Brody LC. Characteristics of users of online personalized genomic risk assessments: implications for physician-patient interactions. Genetics in Medicine : Official Journal of the American College of Medical Genetics. 11: 582-7. PMID 19606049 DOI: 10.1097/Gim.0B013E3181B22C3A  0.344
2009 Mai PL, Chatterjee N, Hartge P, Tucker M, Brody L, Struewing JP, Wacholder S. Potential excess mortality in BRCA1/2 mutation carriers beyond breast, ovarian, prostate, and pancreatic cancers, and melanoma. Plos One. 4: e4812. PMID 19277124 DOI: 10.1371/Journal.Pone.0004812  0.339
2009 Molloy AM, Kirke PN, Troendle JF, Burke H, Sutton M, Brody LC, Scott JM, Mills JL. Maternal vitamin B12 status and risk of neural tube defects in a population with high neural tube defect prevalence and no folic Acid fortification. Pediatrics. 123: 917-23. PMID 19255021 DOI: 10.1542/Peds.2008-1173  0.33
2009 Molloy AM, Brody LC, Mills JL, Scott JM, Kirke PN. The search for genetic polymorphisms in the homocysteine/folate pathway that contribute to the etiology of human neural tube defects. Birth Defects Research. Part a, Clinical and Molecular Teratology. 85: 285-94. PMID 19235830 DOI: 10.1002/Bdra.20566  0.451
2009 Mitchell A, Pangilinan F, Van der Meer J, Molloy AM, Troendle J, Conley M, Kirke PN, Scott JM, Brody LC, Mills JL. Uncoupling protein 2 polymorphisms as risk factors for NTDs. Birth Defects Research. Part a, Clinical and Molecular Teratology. 85: 156-60. PMID 19137581 DOI: 10.1002/Bdra.20520  0.399
2009 Carroll N, Pangilinan F, Molloy AM, Troendle J, Mills JL, Kirke PN, Brody LC, Scott JM, Parle-McDermott A. Analysis of the MTHFD1 promoter and risk of neural tube defects. Human Genetics. 125: 247-56. PMID 19130090 DOI: 10.1007/S00439-008-0616-3  0.425
2008 Greenblatt MS, Brody LC, Foulkes WD, Genuardi M, Hofstra RM, Olivier M, Plon SE, Sijmons RH, Sinilnikova O, Spurdle AB. Locus-specific databases and recommendations to strengthen their contribution to the classification of variants in cancer susceptibility genes. Human Mutation. 29: 1273-81. PMID 18951438 DOI: 10.1002/Humu.20889  0.403
2008 Pangilinan F, Geiler K, Dolle J, Troendle J, Swanson DA, Molloy AM, Sutton M, Conley M, Kirke PN, Scott JM, Mills JL, Brody LC. Construction of a high resolution linkage disequilibrium map to evaluate common genetic variation in TP53 and neural tube defect risk in an Irish population. American Journal of Medical Genetics. Part A. 146: 2617-25. PMID 18798306 DOI: 10.1002/Ajmg.A.32504  0.457
2008 McBride CM, Alford SH, Reid RJ, Larson EB, Baxevanis AD, Brody LC. Putting science over supposition in the arena of personalized genomics. Nature Genetics. 40: 939-42. PMID 18665132 DOI: 10.1038/Ng0808-939  0.315
2008 Mills JL, Molloy AM, Parle-McDermott A, Troendle JF, Brody LC, Conley MR, Cox C, Pangilinan F, Orr DJ, Earley M, McKiernan E, Lynn EC, Doyle A, Scott JM, Kirke PN. Folate-related gene polymorphisms as risk factors for cleft lip and cleft palate. Birth Defects Research. Part a, Clinical and Molecular Teratology. 82: 636-43. PMID 18661527 DOI: 10.1002/Bdra.20491  0.389
2007 McBride CM, Brody LC. Point: genetic risk feedback for common disease time to test the waters. Cancer Epidemiology, Biomarkers & Prevention : a Publication of the American Association For Cancer Research, Cosponsored by the American Society of Preventive Oncology. 16: 1724-6. PMID 17855688 DOI: 10.1158/1055-9965.Epi-07-0102  0.372
2007 Parle-McDermott A, Pangilinan F, Mills JL, Kirke PN, Gibney ER, Troendle J, O'Leary VB, Molloy AM, Conley M, Scott JM, Brody LC. The 19-bp deletion polymorphism in intron-1 of dihydrofolate reductase (DHFR) may decrease rather than increase risk for spina bifida in the Irish population. American Journal of Medical Genetics. Part A. 143: 1174-80. PMID 17486595 DOI: 10.1002/Ajmg.A.31725  0.421
2007 Lawrance AK, Deng L, Brody LC, Finnell RH, Shane B, Rozen R. Genetic and nutritional deficiencies in folate metabolism influence tumorigenicity in Apcmin/+ mice. The Journal of Nutritional Biochemistry. 18: 305-12. PMID 16963246 DOI: 10.1016/J.Jnutbio.2006.06.001  0.302
2007 Alter BP, Rosenberg PS, Brody LC. Clinical and molecular features associated with biallelic mutations in FANCD1/BRCA2. Journal of Medical Genetics. 44: 1-9. PMID 16825431 DOI: 10.1136/Jmg.2006.043257  0.374
2006 Parle-McDermott A, Mills JL, Molloy AM, Carroll N, Kirke PN, Cox C, Conley MR, Pangilinan FJ, Brody LC, Scott JM. The MTHFR 1298CC and 677TT genotypes have opposite associations with red cell folate levels. Molecular Genetics and Metabolism. 88: 290-4. PMID 16621645 DOI: 10.1016/J.Ymgme.2006.02.011  0.381
2006 Parle-McDermott A, Kirke PN, Mills JL, Molloy AM, Cox C, O'Leary VB, Pangilinan F, Conley M, Cleary L, Brody LC, Scott JM. Confirmation of the R653Q polymorphism of the trifunctional C1-synthase enzyme as a maternal risk for neural tube defects in the Irish population. European Journal of Human Genetics : Ejhg. 14: 768-72. PMID 16552426 DOI: 10.1038/Sj.Ejhg.5201603  0.43
2006 O'leary VB, Pangilinan F, Cox C, Parle-McDermott A, Conley M, Molloy AM, Kirke PN, Mills JL, Brody LC, Scott JM. Reduced folate carrier polymorphisms and neural tube defect risk. Molecular Genetics and Metabolism. 87: 364-9. PMID 16343969 DOI: 10.1016/J.Ymgme.2005.09.024  0.389
2006 Alter BP, Rosenberg PS, Brody LC. Biallelic Mutations in FANCD1/BRCA2 Are Associated with Extraordinary Risks of Cancer. Blood. 108: 4326-4326. DOI: 10.1182/Blood.V108.11.4326.4326  0.38
2005 O'Leary VB, Mills JL, Parle-McDermott A, Pangilinan F, Molloy AM, Cox C, Weiler A, Conley M, Kirke PN, Scott JM, Brody LC. Screening for new MTHFR polymorphisms and NTD risk. American Journal of Medical Genetics. Part A. 138: 99-106. PMID 16145688 DOI: 10.1002/Ajmg.A.30846  0.407
2005 Parle-McDermott A, Pangilinan F, Mills JL, Signore CC, Molloy AM, Cotter A, Conley M, Cox C, Kirke PN, Scott JM, Brody LC. A polymorphism in the MTHFD1 gene increases a mother's risk of having an unexplained second trimester pregnancy loss. Molecular Human Reproduction. 11: 477-80. PMID 16123074 DOI: 10.1093/Molehr/Gah204  0.343
2005 O'Leary VB, Mills JL, Pangilinan F, Kirke PN, Cox C, Conley M, Weiler A, Peng K, Shane B, Scott JM, Parle-McDermott A, Molloy AM, Brody LC. Analysis of methionine synthase reductase polymorphisms for neural tube defects risk association. Molecular Genetics and Metabolism. 85: 220-7. PMID 15979034 DOI: 10.1016/J.Ymgme.2005.02.003  0.4
2005 Mills JL, Druschel CM, Pangilinan F, Pass K, Cox C, Seltzer RR, Conley MR, Brody LC. Folate-related genes and omphalocele. American Journal of Medical Genetics. Part A. 136: 8-11. PMID 15937947 DOI: 10.1002/ajmg.a.30772  0.313
2005 Swanson DA, Pangilinan F, Mills JL, Kirke PN, Conley M, Weiler A, Frey T, Parle-McDermott A, O'Leary VB, Seltzer RR, Moynihan KA, Molloy AM, Burke H, Scott JM, Brody LC. Evaluation of transcobalamin II polymorphisms as neural tube defect risk factors in an Irish population. Birth Defects Research. Part a, Clinical and Molecular Teratology. 73: 239-44. PMID 15782407 DOI: 10.1002/Bdra.20122  0.433
2005 Parle-McDermott A, Mills JL, Kirke PN, Cox C, Signore CC, Kirke S, Molloy AM, O'Leary VB, Pangilinan FJ, O'Herlihy C, Brody LC, Scott JM. MTHFD1 R653Q polymorphism is a maternal genetic risk factor for severe abruptio placentae. American Journal of Medical Genetics. Part A. 132: 365-8. PMID 15633187 DOI: 10.1002/Ajmg.A.30354  0.355
2004 Kirke PN, Mills JL, Molloy AM, Brody LC, O'Leary VB, Daly L, Murray S, Conley M, Mayne PD, Smith O, Scott JM. Impact of the MTHFR C677T polymorphism on risk of neural tube defects: case-control study. Bmj (Clinical Research Ed.). 328: 1535-6. PMID 15155469 DOI: 10.1136/Bmj.38036.646030.Ee  0.38
2004 Coyne RS, McDonald HB, Edgemon K, Brody LC. Functional characterization of BRCA1 sequence variants using a yeast small colony phenotype assay. Cancer Biology & Therapy. 3: 453-7. PMID 15004537 DOI: 10.4161/Cbt.3.5.809  0.384
2003 Parle-McDermott A, McManus EJ, Mills JL, O'Leary VB, Pangilinan F, Cox C, Weiler A, Molloy AM, Conley M, Watson D, Scott JM, Brody LC, Kirke PN. Polymorphisms within the vitamin B12 dependent methylmalonyl-coA mutase are not risk factors for neural tube defects. Molecular Genetics and Metabolism. 80: 463-8. PMID 14654360 DOI: 10.1016/J.Ymgme.2003.09.009  0.434
2003 Kanaan Y, Kpenu E, Utley K, Adams-Campbell L, Dunston GM, Brody LC, Broome C. Inherited BRCA2 mutations in African Americans with breast and/or ovarian cancer: a study of familial and early onset cases. Human Genetics. 113: 452-60. PMID 12942367 DOI: 10.1007/S00439-003-0999-0  0.379
2003 O'Leary VB, Mills JL, Kirke PN, Parle-McDermott A, Swanson DA, Weiler A, Pangilinan F, Conley M, Molloy AM, Lynch M, Cox C, Scott JM, Brody LC. Analysis of the human folate receptor beta gene for an association with neural tube defects. Molecular Genetics and Metabolism. 79: 129-33. PMID 12809644 DOI: 10.1016/S1096-7192(03)00075-1  0.413
2003 Parle-McDermott A, Mills JL, Kirke PN, O'Leary VB, Swanson DA, Pangilinan F, Conley M, Molloy AM, Cox C, Scott JM, Brody LC. Analysis of the MTHFR 1298A-->C and 677C-->T polymorphisms as risk factors for neural tube defects. Journal of Human Genetics. 48: 190-3. PMID 12730722 DOI: 10.1007/S10038-003-0008-4  0.395
2002 Brody LC, Conley M, Cox C, Kirke PN, McKeever MP, Mills JL, Molloy AM, O'Leary VB, Parle-McDermott A, Scott JM, Swanson DA. A polymorphism, R653Q, in the trifunctional enzyme methylenetetrahydrofolate dehydrogenase/methenyltetrahydrofolate cyclohydrolase/formyltetrahydrofolate synthetase is a maternal genetic risk factor for neural tube defects: report of the Birth Defects Research Group. American Journal of Human Genetics. 71: 1207-15. PMID 12384833 DOI: 10.1086/344213  0.447
2002 Brody LC. CHEKs and balances: accounting for breast cancer. Nature Genetics. 31: 3-4. PMID 11984555 DOI: 10.1038/Ng0502-3  0.312
2002 Hartge P, Chatterjee N, Wacholder S, Brody LC, Tucker MA, Struewing JP. Breast cancer risk in Ashkenazi BRCA1/2 mutation carriers: effects of reproductive history. Epidemiology (Cambridge, Mass.). 13: 255-61. PMID 11964925 DOI: 10.1097/00001648-200205000-00004  0.36
2001 Eng C, Brody LC, Wagner TM, Devilee P, Vijg J, Szabo C, Tavtigian SV, Nathanson KL, Ostrander E, Frank TS. Interpreting epidemiological research: blinded comparison of methods used to estimate the prevalence of inherited mutations in BRCA1. Journal of Medical Genetics. 38: 824-33. PMID 11748305 DOI: 10.1136/Jmg.38.12.824  0.356
2001 Chatterjee N, Shih J, Hartge P, Brody L, Tucker M, Wacholder S. Association and aggregation analysis using kin-cohort designs with applications to genotype and family history data from the Washington Ashkenazi Study. Genetic Epidemiology. 21: 123-138. PMID 11507721 DOI: 10.1002/Gepi.1022  0.369
2001 Tian H, Brody LC, Fan S, Huang Z, Landers JP. Capillary and microchip electrophoresis for rapid detection of known mutations by combining allele-specific DNA amplification with heteroduplex analysis Clinical Chemistry. 47: 173-185. PMID 11159764 DOI: 10.1093/Clinchem/47.2.173  0.323
2000 Tian H, Brody LC, Landers JP. Rapid detection of deletion, insertion, and substitution mutations via heteroduplex analysis using capillary- and microchip-based electrophoresis Genome Research. 10: 1403-1413. PMID 10984458 DOI: 10.1101/Gr.132700  0.327
2000 Szabo C, Masiello A, Ryan JF, Brody LC. The breast cancer information core: database design, structure, and scope. Human Mutation. 16: 123-31. PMID 10923033 DOI: 10.1002/1098-1004(200008)16:2<123::Aid-Humu4>3.0.Co;2-Y  0.333
2000 Tian H, Jaquins-Gerstl A, Munro N, Trucco M, Brody LC, Landers JP. Single-strand conformation polymorphism analysis by capillary and microchip electrophoresis: a fast, simple method for detection of common mutations in BRCA1 and BRCA2. Genomics. 63: 25-34. PMID 10662541 DOI: 10.1006/Geno.1999.6067  0.374
1999 Panguluri RCK, Brody LC, Modali R, Utley K, Adams-Campbell L, Day AA, Whitfield-Broome C, Dunston GM. BRCA1 mutations in African Americans Human Genetics. 105: 28-31. PMID 10480351 DOI: 10.1007/S004399900085  0.346
1999 Brody LC, Baker PJ, Chines PS, Musick A, Molloy AM, Swanson DA, Kirke PN, Ghosh S, Scott JM, Mills JL. Methionine synthase: high-resolution mapping of the human gene and evaluation as a candidate locus for neural tube defects. Molecular Genetics and Metabolism. 67: 324-33. PMID 10444343 DOI: 10.1006/Mgme.1999.2881  0.384
1999 Hacia JG, Fan JB, Ryder O, Jin L, Edgemon K, Ghandour G, Mayer RA, Sun B, Hsie L, Robbins CM, Brody LC, Wang D, Lander ES, Lipshutz R, Fodor SP, et al. Determination of ancestral alleles for human single-nucleotide polymorphisms using high-density oligonucleotide arrays. Nature Genetics. 22: 164-7. PMID 10369258 DOI: 10.1038/9674  0.381
1999 Yarden RI, Brody LC. BRCA1 interacts with components of the histone deacetylase complex Proceedings of the National Academy of Sciences of the United States of America. 96: 4983-4988. PMID 10220405 DOI: 10.1073/Pnas.96.9.4983  0.305
1999 Hartge P, Struewing JP, Wacholder S, Brody LC, Tucker MA. The prevalence of common BRCA 1 and BRCA2 mutations among Ashkenazi Jews American Journal of Human Genetics. 64: 963-970. PMID 10090881 DOI: 10.1086/302320  0.357
1999 Lee JS, Wacholder S, Struewing JP, McAdams M, Pee D, Brody LC, Tucker MA, Hartge P. Survival after breast cancer in Ashkenazi Jewish BRCA1 and BRCA2 mutation carriers Journal of the National Cancer Institute. 91: 259-263. PMID 10037104 DOI: 10.1093/Jnci/91.3.259  0.322
1998 Hacia JG, Brody LC, Collins FS. Applications of DNA chips for genomic analysis Molecular Psychiatry. 3: 483-492. PMID 9857973 DOI: 10.1038/Sj.Mp.4000475  0.313
1998 Wacholder S, Hartge P, Struewing JP, Pee D, McAdams M, Brody L, Tucker M. The Kin-Cohort Study for Estimating Penetrance American Journal of Epidemiology. 148: 623-630. PMID 9778168 DOI: 10.1093/Aje/148.7.623  0.359
1998 Woodage T, King SM, Wacholder S, Hartge P, Struewing JP, McAdams M, Laken SJ, Tucker MA, Brody LC. The APC I1307K allele and cancer risk in a community-based study of Ashkenazi jews Nature Genetics. 20: 62-65. PMID 9731533 DOI: 10.1038/1722  0.397
1998 Fan S, Wang JA, Yuan RQ, Ma YX, Meng Q, Erdos MR, Brody LC, Goldberg ID, Rosen EM. BRCA1 as a potential human prostate tumor suppressor: Modulation of proliferation, damage responses and expression of cell regulatory proteins Oncogene. 16: 3069-3082. PMID 9662340 DOI: 10.1038/Sj.Onc.1202116  0.308
1998 Brody LC, Biesecker BB. Breast cancer susceptibility genes: BRCA1 and BRCA2 Medicine. 77: 208-226. PMID 9653432 DOI: 10.1097/00005792-199805000-00006  0.398
1998 Hacia JG, Brody LC, Collins FS. New approaches to BRCA1 mutation detection Breast Disease. 10: 45-59. DOI: 10.3233/Bd-1998-101-207  0.356
1997 Brody LC, Biesecker BB. Breast cancer: The high-risk mutations Hospital Practice. 32: 59-80. PMID 9341636 DOI: 10.1080/21548331.1997.11443580  0.396
1997 Humphrey JS, Salim A, Erdos MR, Collins FS, Brody LC, Klausner RD. Human BRCA1 inhibits growth in yeast: potential use in diagnostic testing. Proceedings of the National Academy of Sciences of the United States of America. 94: 5820-5. PMID 9159158 DOI: 10.1073/Pnas.94.11.5820  0.354
1997 Struewing JP, Hartge P, Wacholder S, Baker SM, Berlin M, McAdams M, Timmerman MM, Brody LC, Tucker MA. The risk of cancer associated with specific mutations of BRCA1 and BRCA2 among Ashkenazi Jews. The New England Journal of Medicine. 336: 1401-8. PMID 9145676 DOI: 10.1056/Nejm199705153362001  0.347
1996 Gulati S, Baker P, Li YN, Fowler B, Kruger W, Brody LC, Banerjee R. Defects in human methionine synthase in cblG patients. Human Molecular Genetics. 5: 1859-65. PMID 8968736 DOI: 10.1093/Hmg/5.12.1859  0.324
1996 Li YN, Gulati S, Baker PJ, Brody LC, Banerjee R, Kruger WD. Cloning, mapping and RNA analysis of the human methionine synthase gene. Human Molecular Genetics. 5: 1851-8. PMID 8968735 DOI: 10.1093/Hmg/5.12.1851  0.31
1996 Hacia JG, Brody LC, Chee MS, Fodor SPA, Collins FS. Detection of heterozygous mutations in BRCA1 using high density oligonucleotide arrays and two-colour fluorescence analysis Nature Genetics. 14: 441-449. PMID 8944024 DOI: 10.1016/S0165-4608(97)90265-X  0.368
1996 Oddoux C, Struewing JP, Clayton CM, Neuhausen S, Brody LC, Kaback M, Haas B, Norton L, Borgen P, Jhanwar S, Goldgar D, Ostrer H, Offit K. The carrier frequency of the BRCA2 6174delT mutation among Ashkenazi Jewish individuals is approximately 1% Nature Genetics. 14: 188-190. PMID 8841192 DOI: 10.1038/Ng1096-188  0.35
1996 Schröck E, Badger P, Larson D, Erdos M, Wynshaw-Boris A, Ried T, Brody L. The murine homolog of the human breast and ovarian cancer susceptibility gene Brca1 maps to mouse chromosome 11D. Human Genetics. 97: 256-9. PMID 8566965 DOI: 10.1007/Bf02265277  0.31
1995 Shattuck Eidens D, Mcclure M, Simard J, Labrie F, Narod S, Couch F, Hoskins K, Weber B, Castilla L, Erdos M, Brody L, Friedman L, Ostermeyer E, Szabo C, King MC, et al. A Collaborative Survey of 80 Mutations in the BRCA1 Breast and Ovarian Cancer Susceptibility Gene: Implications for Presymptomatic Testing and Screening Jama: the Journal of the American Medical Association. 273: 535-541. PMID 7837387 DOI: 10.1001/Jama.1995.03520310033026  0.359
1995 Brody LC, Abel KJ, Castilla LH, Couch FJ, McKinley DR, Yin G, Ho PP, Merajver S, Chandrasekharappa SC, Xu J, Cole JL, Struewing JP, Valdes JM, Collins FS, Weber BL. Construction of a transcription map surrounding the BRCA1 locus of human chromosome 17 Genomics. 25: 238-247. PMID 7774924 DOI: 10.1016/0888-7543(95)80131-5  0.306
1995 Weber BL, Abel KJ, Couch FJ, Merajver S, Castilla L, Brody LC, Collins FS. Transcript identification in the BRCA1 candidate region Breast Cancer Research and Treatment. 33: 115-124. PMID 7749139 DOI: 10.1007/Bf00682719  0.379
1995 Struewing JP, Abeliovich D, Peretz T, Avishai N, Kaback MM, Collins FS, Brody LC. The carrier frequency of the BRCA1 185delAG mutation is approximately 1 percent in Ashkenazi Jewish individuals Nature Genetics. 11: 198-200. PMID 7550349 DOI: 10.1038/Ng1095-198  0.361
1994 Castilla LH, Couch FJ, Erdos MR, Hoskins KF, Calzone K, Garber JE, Boyd J, Lubin MB, Deshano ML, Brody LC, Collins FS, Weber BL. Mutations in the BRCA1 gene in families with early-onset breast and ovarian cancer Nature Genetics. 8: 387-391. PMID 7894491 DOI: 10.1038/Ng1294-387  0.379
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