| Year |
Citation |
Score |
| 2023 |
Sutton MM, Duffy MP, Verbruggen SW, Jacobs CR. Osteoclastogenesis requires primary cilia disassembly and can be inhibited by promoting primary cilia formation pharmacologically. Cells, Tissues, Organs. PMID 37231815 DOI: 10.1159/000531098 |
0.403 |
|
| 2022 |
Spasic M, Duffy MP, Jacobs CR. Fenoldopam sensitizes primary cilia-mediated mechanosensing to promote osteogenic intercellular signaling and whole bone adaptation. Journal of Bone and Mineral Research : the Official Journal of the American Society For Bone and Mineral Research. PMID 35230705 DOI: 10.1002/jbmr.4536 |
0.404 |
|
| 2019 |
Moore ER, Chen JC, Jacobs CR. Prx1-Expressing Progenitor Primary Cilia Mediate Bone Formation in response to Mechanical Loading in Mice. Stem Cells International. 2019: 3094154. PMID 31814831 DOI: 10.1155/2019/3094154 |
0.541 |
|
| 2018 |
Moore ER, Yang Y, Jacobs CR. Primary cilia are necessary for Prx1-expressing cells to contribute to postnatal skeletogenesis. Journal of Cell Science. PMID 30002136 DOI: 10.1242/Jcs.217828 |
0.38 |
|
| 2018 |
Moore ER, Zhu YX, Ryu HS, Jacobs CR. Periosteal progenitors contribute to load-induced bone formation in adult mice and require primary cilia to sense mechanical stimulation. Stem Cell Research & Therapy. 9: 190. PMID 29996901 DOI: 10.1186/S13287-018-0930-1 |
0.521 |
|
| 2017 |
Moore ER, Jacobs CR. The primary cilium as a signaling nexus for growth plate function and subsequent skeletal development. Journal of Orthopaedic Research : Official Publication of the Orthopaedic Research Society. PMID 28901584 DOI: 10.1002/Jor.23732 |
0.373 |
|
| 2017 |
Spasic M, Jacobs CR. Primary cilia: Cell and molecular mechanosensors directing whole tissue function. Seminars in Cell & Developmental Biology. PMID 28843978 DOI: 10.1016/J.Semcdb.2017.08.036 |
0.31 |
|
| 2017 |
Spasic M, Jacobs CR. Lengthening primary cilia enhances cellular mechanosensitivity. European Cells & Materials. 33: 158-168. PMID 28217833 DOI: 10.22203/Ecm.V033A12 |
0.324 |
|
| 2015 |
Chen JC, Hoey DA, Chua M, Bellon R, Jacobs CR. Mechanical signals promote osteogenic fate through a primary cilia-mediated mechanism. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. PMID 26675708 DOI: 10.1096/Fj.15-276402 |
0.51 |
|
| 2015 |
Nguyen AM, Young YN, Jacobs CR. The primary cilium is a self-adaptable, integrating nexus for mechanical stimuli and cellular signaling. Biology Open. PMID 26603473 DOI: 10.1016/J.Bpj.2014.11.2763 |
0.341 |
|
| 2015 |
Lee KL, Guevarra MD, Nguyen AM, Chua MC, Wang Y, Jacobs CR. The primary cilium functions as a mechanical and calcium signaling nexus. Cilia. 4: 7. PMID 26029358 DOI: 10.1186/S13630-015-0016-Y |
0.318 |
|
| 2015 |
Duffy MP, Jacobs CR. Seeing the unseen: cell strain and mechanosensing. Biophysical Journal. 108: 1583-4. PMID 25863048 DOI: 10.1016/J.Bpj.2015.03.008 |
0.339 |
|
| 2015 |
Corrigan M, Lee K, Labour M, Jacobs C, Hoey D. Fluid flow-induced bending of the primary cilium triggers a distinct intraciliary calcium flux in mesenchymal stem cells Cilia. 4. DOI: 10.1186/2046-2530-4-S1-P22 |
0.382 |
|
| 2015 |
Spasic M, Jacobs C. Primary Cilia Length is Critical to Cellular Mechanotransduction Biophysical Journal. 108: 561a. DOI: 10.1016/J.Bpj.2014.11.3074 |
0.399 |
|
| 2014 |
Espinha LC, Hoey DA, Fernandes PR, Rodrigues HC, Jacobs CR. Oscillatory fluid flow influences primary cilia and microtubule mechanics. Cytoskeleton (Hoboken, N.J.). 71: 435-45. PMID 25044764 DOI: 10.1002/Cm.21183 |
0.393 |
|
| 2014 |
Lee KL, Hoey DA, Spasic M, Tang T, Hammond HK, Jacobs CR. Adenylyl cyclase 6 mediates loading-induced bone adaptation in vivo Faseb Journal. 28: 1157-1165. PMID 24277577 DOI: 10.1096/Fj.13-240432 |
0.505 |
|
| 2014 |
Downs ME, Nguyen AM, Herzog FA, Hoey DA, Jacobs CR. An experimental and computational analysis of primary cilia deflection under fluid flow. Computer Methods in Biomechanics and Biomedical Engineering. 17: 2-10. PMID 22452422 DOI: 10.1080/10255842.2011.653784 |
0.323 |
|
| 2013 |
Chen JC, Jacobs CR. Mechanically induced osteogenic lineage commitment of stem cells Stem Cell Research and Therapy. 4. PMID 24004875 DOI: 10.1186/Scrt318 |
0.409 |
|
| 2013 |
Leucht P, Temiyasathit S, Russell A, Arguello JF, Jacobs CR, Helms JA, Castillo AB. CXCR4 antagonism attenuates load-induced periosteal bone formation in mice. Journal of Orthopaedic Research : Official Publication of the Orthopaedic Research Society. 31: 1828-38. PMID 23881789 DOI: 10.1002/Jor.22440 |
0.513 |
|
| 2013 |
Nguyen AM, Jacobs CR. Emerging role of primary cilia as mechanosensors in osteocytes. Bone. 54: 196-204. PMID 23201223 DOI: 10.1016/J.Bone.2012.11.016 |
0.453 |
|
| 2013 |
Leucht P, Monica SD, Temiyasathit S, Lenton K, Manu A, Longaker MT, Jacobs CR, Spilker RL, Guo H, Brunski JB, Helms JA. Primary cilia act as mechanosensors during bone healing around an implant. Medical Engineering & Physics. 35: 392-402. PMID 22784673 DOI: 10.1016/J.Medengphy.2012.06.005 |
0.383 |
|
| 2013 |
Chen JC, Castillo AB, Jacobs CR. Cellular and Molecular Mechanotransduction in Bone Osteoporosis: Fourth Edition. 453-475. DOI: 10.1016/B978-0-12-415853-5.00020-0 |
0.343 |
|
| 2012 |
Castillo AB, Blundo JT, Chen JC, Lee KL, Yereddi NR, Jang E, Kumar S, Tang WJ, Zarrin S, Kim JB, Jacobs CR. Focal Adhesion Kinase Plays a Role in Osteoblast Mechanotransduction In Vitro but Does Not Affect Load-Induced Bone Formation In Vivo Plos One. 7. PMID 23028449 DOI: 10.1371/Journal.Pone.0043291 |
0.52 |
|
| 2012 |
Hoey DA, Tormey S, Ramcharan S, O'Brien FJ, Jacobs CR. Primary cilia-mediated mechanotransduction in human mesenchymal stem cells Stem Cells. 30: 2561-2570. PMID 22969057 DOI: 10.1002/Stem.1235 |
0.502 |
|
| 2012 |
Young YN, Downs M, Jacobs CR. Dynamics of the primary cilium in shear flow Biophysical Journal. 103: 629-639. PMID 22947924 DOI: 10.1016/J.Bpj.2012.07.009 |
0.304 |
|
| 2012 |
Hoey DA, Chen JC, Jacobs CR. The primary cilium as a novel extracellular sensor in bone. Frontiers in Endocrinology. 3: 75. PMID 22707948 DOI: 10.3389/Fendo.2012.00075 |
0.484 |
|
| 2012 |
Temiyasathit S, Tang WJ, Leucht P, Anderson CT, Monica SD, Castillo AB, Helms JA, Stearns T, Jacobs CR. Mechanosensing by the primary cilium: deletion of Kif3A reduces bone formation due to loading. Plos One. 7: e33368. PMID 22428034 DOI: 10.1371/Journal.Pone.0033368 |
0.495 |
|
| 2012 |
Hoey DA, Downs ME, Jacobs CR. The mechanics of the primary cilium: An intricate structure with complex function Journal of Biomechanics. 45: 17-26. PMID 21899847 DOI: 10.1016/J.Jbiomech.2011.08.008 |
0.385 |
|
| 2012 |
Hoey DA, Chen JC, Jacobs CR. The primary cilium as a novel extracellular sensor in bone Frontiers in Endocrinology. 3. DOI: 10.3389/fendo.2012.00075 |
0.387 |
|
| 2012 |
Jacobs C, Downs M, Nguyen A, Herzog F, Hoey D. Mechanical behavior of primary cilia. Cilia. 1: 27. DOI: 10.1186/2046-2530-1-S1-P27 |
0.333 |
|
| 2011 |
Lee HG, Minematsu H, Kim KO, Celil Aydemir AB, Shin MJ, Nizami SA, Chung KJ, Hsu AC, Jacobs CR, Lee FY. Actin and ERK1/2-CEBPβ signaling mediates phagocytosis-induced innate immune response of osteoprogenitor cells. Biomaterials. 32: 9197-206. PMID 21899882 DOI: 10.1016/J.Biomaterials.2011.08.059 |
0.356 |
|
| 2011 |
Hoey DA, Kelly DJ, Jacobs CR. A role for the primary cilium in paracrine signaling between mechanically stimulated osteocytes and mesenchymal stem cells Biochemical and Biophysical Research Communications. 412: 182-187. PMID 21810408 DOI: 10.1016/J.Bbrc.2011.07.072 |
0.455 |
|
| 2011 |
Case N, Sen B, Thomas JA, Styner M, Xie Z, Jacobs CR, Rubin J. Steady and oscillatory fluid flows produce a similar osteogenic phenotype Calcified Tissue International. 88: 189-197. PMID 21165611 DOI: 10.1007/S00223-010-9448-Y |
0.349 |
|
| 2011 |
Hoey DA, Jacobs CR. Oscillatory fluid flow affects the osteogenic differentiation of human bone marrow stromal cells in a primary cilium dependent manner Asme 2011 Summer Bioengineering Conference, Sbc 2011. 331-332. DOI: 10.1115/SBC2011-53435 |
0.375 |
|
| 2011 |
Jeon OH, Yoo YM, Kim KH, Jacobs CR, Kim CH. Primary cilia-mediated osteogenic response to fluid flow occurs via increases in focal adhesion and akt signaling pathway in MC3T3-E1 osteoblastic cells Cellular and Molecular Bioengineering. 4: 379-388. DOI: 10.1007/S12195-011-0191-X |
0.435 |
|
| 2010 |
Tummala P, Arnsdorf EJ, Jacobs CR. The Role of Primary Cilia in Mesenchymal Stem Cell Differentiation: A Pivotal Switch in Guiding Lineage Commitment. Cellular and Molecular Bioengineering. 3: 207-212. PMID 20823950 DOI: 10.1007/S12195-010-0127-X |
0.323 |
|
| 2010 |
Arnsdorf EJ, Tummala P, Castillo AB, Zhang F, Jacobs CR. The epigenetic mechanism of mechanically induced osteogenic differentiation Journal of Biomechanics. 43: 2881-2886. PMID 20728889 DOI: 10.1016/J.Jbiomech.2010.07.033 |
0.346 |
|
| 2010 |
Jacobs CR, Temiyasathit S, Castillo AB. Osteocyte mechanobiology and pericellular mechanics Annual Review of Biomedical Engineering. 12: 369-400. PMID 20617941 DOI: 10.1146/Annurev-Bioeng-070909-105302 |
0.388 |
|
| 2010 |
Castillo AB, Jacobs CR. Mesenchymal stem cell mechanobiology Current Osteoporosis Reports. 8: 98-104. PMID 20425617 DOI: 10.1007/S11914-010-0015-2 |
0.351 |
|
| 2010 |
Temiyasathit S, Jacobs CR. Osteocyte primary cilium and its role in bone mechanotransduction Annals of the New York Academy of Sciences. 1192: 422-428. PMID 20392268 DOI: 10.1111/J.1749-6632.2009.05243.X |
0.507 |
|
| 2010 |
Kwon RY, Temiyasathit S, Tummala P, Quah CC, Jacobs CR. Primary cilium-dependent mechanosensing is mediated by adenylyl cyclase 6 and cyclic AMP in bone cells Faseb Journal. 24: 2859-2868. PMID 20371630 DOI: 10.1096/Fj.09-148007 |
0.459 |
|
| 2010 |
Kelly DJ, Jacobs CR. The role of mechanical signals in regulating chondrogenesis and osteogenesis of mesenchymal stem cells Birth Defects Research Part C - Embryo Today: Reviews. 90: 75-85. PMID 20301221 DOI: 10.1002/Bdrc.20173 |
0.351 |
|
| 2010 |
Litzenberger JB, Kim JB, Tummala P, Jacobs CR. β1 Integrins mediate mechanosensitive signaling pathways in Osteocytes Calcified Tissue International. 86: 325-332. PMID 20213106 DOI: 10.1007/S00223-010-9343-6 |
0.421 |
|
| 2010 |
Shivaram GM, Kim CH, Batra NN, Yang W, Harris SE, Jacobs CR. Novel early response genes in osteoblasts exposed to dynamic fluid flow. Philosophical Transactions. Series a, Mathematical, Physical, and Engineering Sciences. 368: 605-16. PMID 20047941 DOI: 10.1098/Rsta.2009.0231 |
0.39 |
|
| 2010 |
Wang L, Shi X, Zhao R, Halloran BP, Clark DJ, Jacobs CR, Kingery WS. Calcitonin-gene-related peptide stimulates stromal cell osteogenic differentiation and inhibits RANKL induced NF-kappaB activation, osteoclastogenesis and bone resorption. Bone. 46: 1369-79. PMID 19962460 DOI: 10.1016/J.Bone.2009.11.029 |
0.46 |
|
| 2010 |
Lee KL, Hoey DA, Jacobs CR. Primary cilia-mediated mechanotransduction in bone Clinical Reviews in Bone and Mineral Metabolism. 8: 201-212. DOI: 10.1007/S12018-010-9078-Y |
0.47 |
|
| 2009 |
Kim CH, Kim KH, Jacobs CR. Effects of high frequency loading on RANKL and OPG mRNA expression in ST-2 murine stromal cells Bmc Musculoskeletal Disorders. 10. PMID 19728893 DOI: 10.1186/1471-2474-10-109 |
0.446 |
|
| 2009 |
Arnsdorf EJ, Tummala P, Jacobs CR. Non-canonical Wnt signalling and N-cadherin related β-catenin signalling play a role in mechanically induced osteogenic cell fate Plos One. 4. PMID 19401766 DOI: 10.1371/Journal.Pone.0005388 |
0.398 |
|
| 2009 |
Wang L, Zhao R, Shi X, Wei T, Halloran BP, Clark DJ, Jacobs CR, Kingery WS. Substance P stimulates bone marrow stromal cell osteogenic activity, osteoclast differentiation, and resorption activity in vitro. Bone. 45: 309-20. PMID 19379851 DOI: 10.1016/J.Bone.2009.04.203 |
0.454 |
|
| 2009 |
Folgado J, Fernandes PR, Jacobs CR, Pellegrini JD. Influence of femoral stem geometry, material and extent of porous coating on bone ingrowth and atrophy in cementless total hip arthroplasty: an iterative finite element model Computer Methods in Biomechanics and Biomedical Engineering. 12: 135-145. PMID 19242833 DOI: 10.1080/10255840802546754 |
0.465 |
|
| 2009 |
Arnsdorf EJ, Jones LM, Carter DR, Jacobs CR. The periosteum as a cellular source for functional tissue engineering. Tissue Engineering. Part A. 15: 2637-42. PMID 19207046 DOI: 10.1089/Ten.Tea.2008.0244 |
0.517 |
|
| 2009 |
Arnsdorf EJ, Tummala P, Kwon RY, Jacobs CR. Mechanically induced osteogenic differentiation - The role of RhoA, ROCKII and cytoskeletal dynamics Journal of Cell Science. 122: 546-553. PMID 19174467 DOI: 10.1242/Jcs.036293 |
0.37 |
|
| 2009 |
Riboh J, Chong AKS, Pham H, Longaker M, Jacobs C, Chang J. Optimization of Flexor Tendon Tissue Engineering With a Cyclic Strain Bioreactor Journal of Hand Surgery (European Volume). 33: 1388-1396. PMID 18929207 DOI: 10.1016/J.Jhsa.2008.04.019 |
0.315 |
|
| 2009 |
Litzenberger JB, Tang WJ, Castillo AB, Jacobs CR. Deletion of β1 integrins from cortical osteocytes reduces load-induced bone formation Cellular and Molecular Bioengineering. 2: 416-424. DOI: 10.1007/S12195-009-0068-4 |
0.456 |
|
| 2009 |
Kwon RY, Temiyasathit S, Tummala P, Quah C, Jacobs CR. Primary cilia mediate intracellular cAMP responses in bone cells exposed to dynamic fluid flow Proceedings of the Asme Summer Bioengineering Conference, Sbc2008. 321-322. |
0.351 |
|
| 2008 |
Nelson ER, Huang Z, Ma T, Lindsey D, Jacobs C, Smith RL, Goodman SB. New bone formation by murine osteoprogenitor cells cultured on corticocancellous allograft bone. Journal of Orthopaedic Research : Official Publication of the Orthopaedic Research Society. 26: 1660-4. PMID 18524004 DOI: 10.1002/jor.20676 |
0.374 |
|
| 2008 |
You L, Temiyasathit S, Lee P, Kim CH, Tummala P, Yao W, Kingery W, Malone AM, Kwon RY, Jacobs CR. Osteocytes as mechanosensors in the inhibition of bone resorption due to mechanical loading. Bone. 42: 172-9. PMID 17997378 DOI: 10.1016/J.Bone.2007.09.047 |
0.522 |
|
| 2008 |
Sabsovich I, Clark JD, Liao G, Peltz G, Lindsey DP, Jacobs CR, Yao W, Guo TZ, Kingery WS. Bone microstructure and its associated genetic variability in 12 inbred mouse strains: microCT study and in silico genome scan. Bone. 42: 439-51. PMID 17967568 DOI: 10.1016/J.Bone.2007.09.041 |
0.409 |
|
| 2008 |
Malone AMD, Anderson CT, Tummala P, Kwon RY, Johnston TR, Stearns T, Jacobs CR. Primary cilia mediate mechanosensing in bone cells by a calcium-independent mechanism (Proceedings of the National Academy of Sciences of the United States of America (2007) 104, (13325-13330) DOI: 10.1073/pnas.0700636104) Proceedings of the National Academy of Sciences of the United States of America. 105: 825. DOI: 10.1073/Pnas.0711497105 |
0.407 |
|
| 2008 |
Malone A, Anderson C, Sterns T, Jacobs C. Primary cilia as mechanosensors in bone Bone. 43: S53-S54. DOI: 10.1016/J.Bone.2008.08.045 |
0.469 |
|
| 2008 |
You L, Temiyasathit S, Coyer SR, García AJ, Jacobs CR. Bone Cells Grown on Micropatterned Surfaces are More Sensitive to Fluid Shear Stress Cellular and Molecular Bioengineering. 1: 182-188. DOI: 10.1007/S12195-008-0017-7 |
0.475 |
|
| 2008 |
You L, Temiyasathit S, Tao E, Prinz F, Jacobs CR. 3D Microfluidic Approach to Mechanical Stimulation of Osteocyte Processes Cellular and Molecular Bioengineering. 1: 103-107. DOI: 10.1007/S12195-008-0010-1 |
0.513 |
|
| 2007 |
Malone AM, Anderson CT, Stearns T, Jacobs CR. Primary cilia in bone. Journal of Musculoskeletal & Neuronal Interactions. 7: 301. PMID 18094482 |
0.368 |
|
| 2007 |
Malone AM, Anderson CT, Tummala P, Kwon RY, Johnston TR, Stearns T, Jacobs CR. Primary cilia mediate mechanosensing in bone cells by a calcium-independent mechanism. Proceedings of the National Academy of Sciences of the United States of America. 104: 13325-30. PMID 17673554 DOI: 10.1073/Pnas.0700636104 |
0.532 |
|
| 2007 |
Kwon RY, Jacobs CR. Time-dependent deformations in bone cells exposed to fluid flow in vitro: investigating the role of cellular deformation in fluid flow-induced signaling Journal of Biomechanics. 40: 3162-3168. PMID 17559856 DOI: 10.1016/J.Jbiomech.2007.04.003 |
0.467 |
|
| 2007 |
Malone AM, Batra NN, Shivaram G, Kwon RY, You L, Kim CH, Rodriguez J, Jair K, Jacobs CR. The role of actin cytoskeleton in oscillatory fluid flow-induced signaling in MC3T3-E1 osteoblasts. American Journal of Physiology. Cell Physiology. 292: C1830-6. PMID 17251324 DOI: 10.1152/Ajpcell.00352.2005 |
0.39 |
|
| 2007 |
Godin LM, Suzuki S, Jacobs CR, Donahue HJ, Donahue SW. Mechanically induced intracellular calcium waves in osteoblasts demonstrate calcium fingerprints in bone cell mechanotransduction. Biomechanics and Modeling in Mechanobiology. 6: 391-8. PMID 17082961 DOI: 10.1007/S10237-006-0059-5 |
0.346 |
|
| 2006 |
Kim CH, You L, Yellowley CE, Jacobs CR. Oscillatory fluid flow-induced shear stress decreases osteoclastogenesis through RANKL and OPG signaling. Bone. 39: 1043-7. PMID 16860618 DOI: 10.1016/J.Bone.2006.05.017 |
0.514 |
|
| 2006 |
Rubin J, Rubin C, Jacobs CR. Molecular pathways mediating mechanical signaling in bone. Gene. 367: 1-16. PMID 16361069 DOI: 10.1016/J.Gene.2005.10.028 |
0.455 |
|
| 2006 |
Clowes-Arnsdorf EJ, Kwon RY, Tummala P, Carter DR, Jacobs CR. The role of actin cytoskeletal tension in oscillatory fluid flow induced osteogenesis McB Molecular and Cellular Biomechanics. 3: 205-206. |
0.501 |
|
| 2005 |
Batra NN, Li YJ, Yellowley CE, You L, Malone AM, Kim CH, Jacobs CR. Effects of short-term recovery periods on fluid-induced signaling in osteoblastic cells. Journal of Biomechanics. 38: 1909-17. PMID 16023480 DOI: 10.1016/J.Jbiomech.2004.08.009 |
0.513 |
|
| 2005 |
Offley SC, Guo TZ, Wei T, Clark JD, Vogel H, Lindsey DP, Jacobs CR, Yao W, Lane NE, Kingery WS. Capsaicin-sensitive sensory neurons contribute to the maintenance of trabecular bone integrity Journal of Bone and Mineral Research. 20: 257-267. PMID 15647820 DOI: 10.1359/Jbmr.041108 |
0.416 |
|
| 2005 |
Malone AM, Narain R, Jacobs CR. Biomechanical regulation of mesenchymal stem and progenitor cells and the implications for regenerative medicine Current Opinion in Orthopaedics. 16: 363-367. DOI: 10.1097/01.Bco.0000178253.32694.F3 |
0.405 |
|
| 2004 |
Li YJ, Batra NN, You L, Meier SC, Coe IA, Yellowley CE, Jacobs CR. Oscillatory fluid flow affects human marrow stromal cell proliferation and differentiation. Journal of Orthopaedic Research : Official Publication of the Orthopaedic Research Society. 22: 1283-9. PMID 15475210 DOI: 10.1016/J.Orthres.2004.04.002 |
0.507 |
|
| 2004 |
Haut Donahue TL, Genetos DC, Jacobs CR, Donahue HJ, Yellowley CE. Annexin V disruption impairs mechanically induced calcium signaling in osteoblastic cells Bone. 35: 656-663. PMID 15336601 DOI: 10.1016/J.Bone.2004.04.025 |
0.462 |
|
| 2003 |
Kingery WS, Offley SC, Guo TZ, Davies MF, Clark JD, Jacobs CR. A substance P receptor (NK1) antagonist enhances the widespread osteoporotic effects of sciatic nerve section Bone. 33: 927-936. PMID 14678852 DOI: 10.1016/J.Bone.2003.07.003 |
0.356 |
|
| 2003 |
Reilly GC, Haut TR, Yellowley CE, Donahue HJ, Jacobs CR. Fluid flow induced PGE2 release by bone cells is reduced by glycocalyx degradation whereas calcium signals are not. Biorheology. 40: 591-603. PMID 14610310 |
0.328 |
|
| 2003 |
Alford AI, Jacobs CR, Donahue HJ. Oscillating fluid flow regulates gap junction communication in osteocytic MLO-Y4 cells by an ERK1/2 MAP kinase-dependent mechanism Bone. 33: 64-70. PMID 12919700 DOI: 10.1016/S8756-3282(03)00167-4 |
0.318 |
|
| 2003 |
Donahue TLH, Haut TR, Yellowley CE, Donahue HJ, Jacobs CR. Mechanosensitivity of bone cells to oscillating fluid flow induced shear stress may be modulated by chemotransport Journal of Biomechanics. 36: 1363-1371. PMID 12893045 DOI: 10.1016/S0021-9290(03)00118-0 |
0.412 |
|
| 2003 |
Saunders MM, You J, Zhou Z, Li Z, Yellowley CE, Kunze EL, Jacobs CR, Donahue HJ. Fluid flow-induced prostaglandin E2 response of osteoblastic ROS 17/2.8 cells is gap junction-mediated and independent of cytosolic calcium Bone. 32: 350-356. PMID 12689677 DOI: 10.1016/S8756-3282(03)00025-5 |
0.481 |
|
| 2003 |
Donahue SW, Donahue HJ, Jacobs CR. Osteoblastic cells have refractory periods for fluid-flow-induced intracellular calcium oscillations for short bouts of flow and display multiple low-magnitude oscillations during long-term flow. Journal of Biomechanics. 36: 35-43. PMID 12485636 DOI: 10.1016/S0021-9290(02)00318-4 |
0.395 |
|
| 2003 |
Haut Donahue TL, Hull ML, Rashid MM, Jacobs CR. How the stiffness of meniscal attachments and meniscal material properties affect tibio-femoral contact pressure computed using a validated finite element model of the human knee joint. Journal of Biomechanics. 36: 19-34. PMID 12485635 DOI: 10.1016/S0021-9290(02)00305-6 |
0.312 |
|
| 2002 |
You J, Jacobs CR, Steinberg TH, Donahue HJ. P2Y purinoceptors are responsible for oscillatory fluid flow-induced intracellular calcium mobilization in osteoblastic cells. The Journal of Biological Chemistry. 277: 48724-9. PMID 12376532 DOI: 10.1074/Jbc.M209245200 |
0.309 |
|
| 2002 |
Donahue TL, Hull ML, Rashid MM, Jacobs CR. A finite element model of the human knee joint for the study of tibio-femoral contact. Journal of Biomechanical Engineering. 124: 273-80. PMID 12071261 DOI: 10.1115/1.1470171 |
0.364 |
|
| 2002 |
Fernandes PR, Folgado J, Jacobs C, Pellegrini V. A contact model with ingrowth control for bone remodelling around cementless stems. Journal of Biomechanics. 35: 167-76. PMID 11784535 DOI: 10.1016/S0021-9290(01)00204-4 |
0.495 |
|
| 2002 |
Buhl KM, Jacobs CR, Turner RT, Evans GL, Farrell PA, Donahue HJ. Parallel changes in extracellular matrix protein gene expression, bone formation and biomechanical properties in aging rat bone Journal of Musculoskeletal Research. 6: 157-169. DOI: 10.1142/S0218957702000848 |
0.457 |
|
| 2002 |
Jacobs CR. Bone mechanics handbook (second edition) Journal of Biomechanics. 35: 723-724. DOI: 10.1016/S0021-9290(01)00251-2 |
0.475 |
|
| 2001 |
Saunders MM, You J, Trosko JE, Yamasaki H, Li Z, Donahue HJ, Jacobs CR. Gap junctions and fluid flow response in MC3T3-E1 cells American Journal of Physiology - Cell Physiology. 281. PMID 11698250 DOI: 10.1152/Ajpcell.2001.281.6.C1917 |
0.372 |
|
| 2001 |
Donahue SW, Jacobs CR, Donahue HJ. Flow-induced calcium oscillations in rat osteoblasts are age, loading frequency, and shear stress dependent American Journal of Physiology - Cell Physiology. 281: C1635-C1641. PMID 11600427 DOI: 10.1152/Ajpcell.2001.281.5.C1635 |
0.48 |
|
| 2001 |
Edlich M, Yellowley CE, Jacobs CR, Donahue HJ. Oscillating fluid flow regulates cytosolic calcium concentration in bovine articular chondrocytes Journal of Biomechanics. 34: 59-65. PMID 11425081 DOI: 10.1016/S0021-9290(00)00158-5 |
0.333 |
|
| 2001 |
You J, Reilly GC, Zhen X, Yellowley CE, Chen Q, Donahue HJ, Jacobs CR. Osteopontin Gene Regulation by Oscillatory Fluid Flow via Intracellular Calcium Mobilization and Activation of Mitogen-activated Protein Kinase in MC3T3-E1 Osteoblasts Journal of Biological Chemistry. 276: 13365-13371. PMID 11278573 DOI: 10.1074/Jbc.M009846200 |
0.389 |
|
| 2001 |
Kurokouchi K, Jacobs CR, Donahue HJ. Oscillating Fluid Flow Inhibits TNF-α-induced NF-κB Activation via an IκB Kinase Pathway in Osteoblast-like UMR106 Cells Journal of Biological Chemistry. 276: 13499-13504. PMID 11096064 DOI: 10.1074/Jbc.M003795200 |
0.302 |
|
| 2001 |
Jacobs CR, You J, Reilly G, Saunders MM, Kurokouchi K, Yellowley CE, Donahue HJ. An overview of oscialltory fluid flow as a potent loading-induced physical signal in bone cells American Society of Mechanical Engineers, Bioengineering Division (Publication) Bed. 50: 339-340. |
0.353 |
|
| 2000 |
Black KP, Saunders MM, Stube KC, Moulton MJR, Jacobs CR. Effects of interference fit screw length on tibial tunnel fixation for anterior cruciate ligament reconstruction American Journal of Sports Medicine. 28: 846-849. PMID 11101107 DOI: 10.1177/03635465000280061201 |
0.347 |
|
| 2000 |
You J, Yellowley CE, Donahue HJ, Zhang Y, Chen Q, Jacobs CR. Substrate deformation levels associated with routine physical activity are less stimulatory to bone cells relative to loading-induced oscillatory fluid flow Journal of Biomechanical Engineering. 122: 387-393. PMID 11036562 DOI: 10.1115/1.1287161 |
0.485 |
|
| 2000 |
Lesh ML, Schneider DJ, Deol G, Davis B, Jacobs CR, Pellegrini V.D. J. The consequences of anterior femoral notching in total knee arthroplasty: A Biomechanical study Journal of Bone and Joint Surgery - Series A. 82: 1096-1101. PMID 10954098 DOI: 10.2106/00004623-200008000-00005 |
0.316 |
|
| 2000 |
Eckstein F, Merz B, Jacobs CR. Effects of joint incongruity on articular pressure distribution and subchondral bone remodeling Advances in Anatomy, Embryology, and Cell Biology. 152. PMID 10857219 |
0.309 |
|
| 2000 |
Jacobs CR. The mechanobiology of cancellous bone structural adaptation Journal of Rehabilitation Research and Development. 37: 209-216. PMID 10850827 |
0.408 |
|
| 2000 |
Malecki EA, Buhl KM, Beard JL, Jacobs CR, Connor JR, Donahue HJ. Bone structural and mechanical properties are affected by hypotransferrinemia but not by iron deficiency in mice Journal of Bone and Mineral Research. 15: 271-277. PMID 10703928 DOI: 10.1359/Jbmr.2000.15.2.271 |
0.334 |
|
| 2000 |
Yellowley CE, Li Z, Zhou Z, Jacobs CR, Donahue HJ. Functional gap junctions between osteocytic and osteoblastic cells Journal of Bone and Mineral Research. 15: 209-217. PMID 10703922 DOI: 10.1359/Jbmr.2000.15.2.209 |
0.391 |
|
| 2000 |
Yellowley C, Zhang Y, Jacobs C, Donahue H. Oscillating fluid flow increases calcium and annexin V MRNA expression in bone cells Bone. 27: 37. DOI: 10.1016/S8756-3282(00)80129-5 |
0.416 |
|
| 2000 |
Jacobs C, You J, Yellowley C, Donahue H. Mechanotransduction in bone cells via oscillating flow Bone. 27: 16. DOI: 10.1016/S8756-3282(00)80046-0 |
0.46 |
|
| 1999 |
Fischer KJ, Jacobs CR, Levenston ME, Cody DD, Carter DR. Proximal Femoral Density Patterns are Consistent with Bicentric Joint Loads. Computer Methods in Biomechanics and Biomedical Engineering. 2: 271-283. PMID 11264832 DOI: 10.1080/10255849908907992 |
0.71 |
|
| 1999 |
Fernandes P, Rodrigues H, Jacobs C. A Model of Bone Adaptation Using a Global Optimisation Criterion Based on the Trajectorial Theory of Wolff. Computer Methods in Biomechanics and Biomedical Engineering. 2: 125-138. PMID 11264822 DOI: 10.1080/10255849908907982 |
0.447 |
|
| 1999 |
Jacobs CR, Davis BR, Rieger CJ, Francis JJ, Saad M, Fyhrie DP. NACOB presentation to ASB Young Scientist Award: Postdoctoral. The impact of boundary conditions and mesh size on the accuracy of cancellous bone tissue modulus determination using large-scale finite-element modeling. North American Congress on Biomechanics. Journal of Biomechanics. 32: 1159-64. PMID 10541065 DOI: 10.1016/S0021-9290(99)00115-3 |
0.609 |
|
| 1999 |
Yellowley CE, Jacobs CR, Donahue HJ. Mechanisms contributing to fluid-flow-induced Ca2+ mobilization in articular chondrocytes Journal of Cellular Physiology. 180: 402-408. PMID 10430180 DOI: 10.1002/(Sici)1097-4652(199909)180:3<402::Aid-Jcp11>3.0.Co;2-4 |
0.314 |
|
| 1999 |
Eckstein F, Merz B, Schön M, Jacobs CR, Putz R. Tension and bending, but not compression alone determine the functional adaptation of subchondral bone in incongruous joints Anatomy and Embryology. 199: 85-97. PMID 9924938 DOI: 10.1007/S004290050212 |
0.425 |
|
| 1999 |
You J, Yellowley CE, Donahue HJ, Jacobs CR. Physiological levels of substrate deformation are less stimulatory to bone cells compared to fluid flow American Society of Mechanical Engineers, Bioengineering Division (Publication) Bed. 43: 161-162. |
0.36 |
|
| 1998 |
Fischer KJ, Jacobs CR, Levenston ME, Cody DD, Carter DR. Bone Load Estimation for the Proximal Femur Using Single Energy Quantitative CT Data. Computer Methods in Biomechanics and Biomedical Engineering. 1: 233-245. PMID 11264806 DOI: 10.1080/01495739808936704 |
0.72 |
|
| 1998 |
Jacobs CR, Yellowley CE, Davis BR, Zhou Z, Cimbala JM, Donahue HJ. Differential effect of steady versus oscillating flow on bone cells Journal of Biomechanics. 31: 969-976. PMID 9880053 DOI: 10.1016/S0021-9290(98)00114-6 |
0.409 |
|
| 1998 |
Eckstein F, Jacobs CR, Merz BR. Mechanobiological adaptation of subchondral bone as a function of joint incongruity and loading. Medical Engineering & Physics. 19: 720-8. PMID 9450256 DOI: 10.1016/S1350-4533(97)00031-3 |
0.46 |
|
| 1998 |
Jacobs CR, Davis BR, Naidu SH, Pellegrini VD, Case KL. Comparison of the fatigue lifetimes of simplex P and osteobond bone cement American Society of Mechanical Engineers, Bioengineering Division (Publication) Bed. 39: 353-354. |
0.32 |
|
| 1997 |
Jacobs CR, Eckstein F. Computer simulation of subchondral bone adaptation to mechanical loading in an incongruous joint Anatomical Record. 249: 317-326. PMID 9372165 DOI: 10.1002/(Sici)1097-0185(199711)249:3<317::Aid-Ar2>3.0.Co;2-R |
0.531 |
|
| 1997 |
Yellowley CE, Jacobs CR, Li Z, Zhou Z, Donahue HJ. Effects of fluid flow on intracellular calcium in bovine articular chondrocytes American Journal of Physiology - Cell Physiology. 273. PMID 9252439 DOI: 10.1152/Ajpcell.1997.273.1.C30 |
0.314 |
|
| 1997 |
Jacobs CR, Simo JC, Beaupré GS, Carter DR. Adaptive bone remodeling incorporating simultaneous density and anisotropy considerations. Journal of Biomechanics. 30: 603-13. PMID 9165394 DOI: 10.1016/S0021-9290(96)00189-3 |
0.638 |
|
| 1997 |
Fischer KJ, Jacobs CR, Levenston ME, Carter DR. Observations of convergence and uniqueness of node-based bone remodeling simulations Annals of Biomedical Engineering. 25: 261-268. PMID 9084831 DOI: 10.1007/Bf02648040 |
0.728 |
|
| 1996 |
Fischer KJ, Jacobs CR, Levenston ME, Carter DR. Different loads can produce similar bone density distributions Bone. 19: 127-135. PMID 8853856 DOI: 10.1016/8756-3282(96)00140-8 |
0.745 |
|
| 1995 |
Jacobs CR, Levenston ME, Beaupré GS, Simo JC, Carter DR. Numerical instabilities in bone remodeling simulations: the advantages of a node-based finite element approach. Journal of Biomechanics. 28: 449-59. PMID 7738054 DOI: 10.1016/0021-9290(94)00087-K |
0.733 |
|
| 1995 |
Fischer KJ, Jacobs CR, Carter DR. Computational method for determination of bone and joint loads using bone density distributions Journal of Biomechanics. 28: 1127-1135. PMID 7559684 DOI: 10.1016/0021-9290(94)00182-4 |
0.659 |
|
| 1994 |
Levenston ME, Beaupré GS, Jacobs CR, Carter DR. The role of loading memory in bone adaptation simulations Bone. 15: 177-186. PMID 8086235 DOI: 10.1016/8756-3282(94)90705-6 |
0.735 |
|
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