| Year |
Citation |
Score |
| 2024 |
Sykes EME, Mateo-Estrada V, Engelberg R, Muzaleva A, Zhanel G, Dettman J, Chapados J, Gerdis S, Akineden Ö, Khan IUH, Castillo-Ramírez S, Kumar A. Phylogenomic and phenotypic analyses highlight the diversity of antibiotic resistance and virulence in both human and non-human . Msphere. e0074123. PMID 38440986 DOI: 10.1128/msphere.00741-23 |
0.49 |
|
| 2023 |
Rotstein C, Lynch JP, Zhanel GG. Hospital-acquired bacterial pneumonia (HABP) and ventilator-associated bacterial pneumonia (VABP) in Canada: treatment update and the role of new IV antimicrobials. Expert Review of Anti-Infective Therapy. 1-13. PMID 37811572 DOI: 10.1080/14787210.2023.2268287 |
0.406 |
|
| 2023 |
Sykes EME, Mateo-Estrada V, Zhanel G, Dettman J, Chapados J, Gerdis S, Akineden Ö, Khan IIU, Castillo-Ramírez S, Kumar A. Emergence of ADC-5 Cephalosporinase in environmental from a German tank milk with a novel Sequence Type. Access Microbiology. 5. PMID 37424542 DOI: 10.1099/acmi.0.000485.v3 |
0.498 |
|
| 2023 |
Golden AR, Adam HJ, Karlowsky JA, Baxter M, Schellenberg J, Martin I, Demczuk W, Minion J, Van Caeseele P, Kus JV, McGeer A, Lefebvre B, Smadi H, Haldane D, Yu Y, ... ... Zhanel GG, et al. Genomic investigation of the most common Streptococcus pneumoniae serotypes causing invasive infections in Canada: the SAVE study, 2011-2020. The Journal of Antimicrobial Chemotherapy. 78: i26-i36. PMID 37130587 DOI: 10.1093/jac/dkad067 |
0.305 |
|
| 2023 |
Adam HJ, Karlowsky JA, Baxter MR, Schellenberg J, Golden AR, Martin I, Demczuk W, Mulvey MR, Zhanel GG. Analysis of MDR in the predominant Streptococcus pneumoniae serotypes in Canada: the SAVE study, 2011-2020. The Journal of Antimicrobial Chemotherapy. 78: i17-i25. PMID 37130586 DOI: 10.1093/jac/dkad066 |
0.359 |
|
| 2023 |
Alford MA, Karlowsky JA, Adam HJ, Baxter MR, Schellenberg J, Golden AR, Martin I, Demczuk W, Mulvey MR, Zhanel GG. Antimicrobial susceptibility testing of invasive isolates of Streptococcus pneumoniae from Canadian patients: the SAVE study, 2011-2020. The Journal of Antimicrobial Chemotherapy. 78: i8-i16. PMID 37130584 DOI: 10.1093/jac/dkad065 |
0.407 |
|
| 2022 |
Zamudio R, Boerlin P, Beyrouthy R, Madec JY, Schwarz S, Mulvey MR, Zhanel GG, Cormier A, Chalmers G, Bonnet R, Haenni M, Eichhorn I, Kaspar H, Garcia-Fierro R, Wood JLN, et al. Dynamics of extended-spectrum cephalosporin resistance genes in Escherichia coli from Europe and North America. Nature Communications. 13: 7490. PMID 36509735 DOI: 10.1038/s41467-022-34970-7 |
0.314 |
|
| 2022 |
Lynch JP, Zhanel GG. Escalation of antimicrobial resistance among MRSA part 1: focus on global spread. Expert Review of Anti-Infective Therapy. 1-15. PMID 36470275 DOI: 10.1080/14787210.2023.2154653 |
0.438 |
|
| 2022 |
Walkty A, Karlowsky JA, Lagace-Wiens P, Baxter MR, Adam HJ, Zhanel GG. Antimicrobial resistance patterns of bacterial pathogens recovered from the urine of patients at Canadian hospitals from 2009 to 2020. Jac-Antimicrobial Resistance. 4: dlac122. PMID 36466136 DOI: 10.1093/jacamr/dlac122 |
0.401 |
|
| 2022 |
Ramirez DM, Ramirez D, Arthur G, Zhanel G, Schweizer F. Guanidinylated Polymyxins as Outer Membrane Permeabilizers Capable of Potentiating Rifampicin, Erythromycin, Ceftazidime and Aztreonam against Gram-Negative Bacteria. Antibiotics (Basel, Switzerland). 11. PMID 36289935 DOI: 10.3390/antibiotics11101277 |
0.41 |
|
| 2022 |
Walkty AJ, Karlowsky JA, Baxter MR, Lagace-Wiens PRS, Adam HJ, Zhanel GG. In vitro activity of sulopenem against 1880 bacterial pathogens isolated from Canadian patients with urinary tract infections (CANWARD, 2014-21). The Journal of Antimicrobial Chemotherapy. PMID 36177825 DOI: 10.1093/jac/dkac333 |
0.37 |
|
| 2022 |
Cox GW, Avery BP, Parmley EJ, Irwin RJ, Reid-Smith RJ, Deckert AE, Finley RL, Daignault D, Zhanel GG, Mulvey MR, Bharat A. A One Health Genomic Investigation of Gentamicin Resistance in Escherichia coli from Human and Chicken Sources in Canada, 2014 to 2017. Antimicrobial Agents and Chemotherapy. e0067722. PMID 36165686 DOI: 10.1128/aac.00677-22 |
0.39 |
|
| 2022 |
Karlowsky JA, Baxter MR, Walkty AJ, Lagacé-Wiens PRS, Bay D, Adam HJ, Zhanel GG. In vitro activity of fosfomycin against bacterial pathogens isolated from urine specimens in Canada from 2007 to 2020: CANWARD surveillance study. The Journal of Antimicrobial Chemotherapy. PMID 35971759 DOI: 10.1093/jac/dkac275 |
0.373 |
|
| 2022 |
Gregorchuk BSJ, Reimer SL, Slipski CJ, Milner KA, Hiebert SL, Beniac DR, Booth TF, Zhanel GG, Bay DC. Applying fluorescent dye assays to discriminate Escherichia coli chlorhexidine resistance phenotypes from porin and mlaA deletions and efflux pumps. Scientific Reports. 12: 12149. PMID 35840757 DOI: 10.1038/s41598-022-15775-6 |
0.354 |
|
| 2022 |
Karlowsky JA, Walkty AJ, Baxter MR, Adam HJ, Lagacé-Wiens PRS, Schweizer F, Bay D, Lynch JP, Mulvey MR, Zhanel GG. Activity of Cefiderocol against Extensively Drug-Resistant Pseudomonas aeruginosa: CANWARD, 2007 to 2019. Microbiology Spectrum. e0172422. PMID 35758747 DOI: 10.1128/spectrum.01724-22 |
0.524 |
|
| 2022 |
Zhanel GG, Pozdirca M, Golden AR, Lawrence CK, Zelenitsky S, Berry L, Schweizer F, Bay D, Adam H, Zhanel MA, Lagacé-Wiens P, Walkty A, Irfan N, Naber K, Lynch JP, et al. Sulopenem: An Intravenous and Oral Penem for the Treatment of Urinary Tract Infections Due to Multidrug-Resistant Bacteria. Drugs. PMID 35294769 DOI: 10.1007/s40265-022-01688-1 |
0.441 |
|
| 2022 |
Lynch JP, Clark NM, Zhanel GG. Infections Due to Acinetobacter baumannii-calcoaceticus Complex: Escalation of Antimicrobial Resistance and Evolving Treatment Options. Seminars in Respiratory and Critical Care Medicine. 43: 97-124. PMID 35172361 DOI: 10.1055/s-0041-1741019 |
0.46 |
|
| 2022 |
Golden AR, Baxter MR, Karlowsky JA, Mataseje L, Mulvey MR, Walkty A, Bay D, Schweizer F, Lagace-Wiens PRS, Adam HJ, Zhanel GG. Activity of cefepime/taniborbactam and comparators against whole genome sequenced ertapenem-non-susceptible Enterobacterales clinical isolates: CANWARD 2007-19. Jac-Antimicrobial Resistance. 4: dlab197. PMID 35156028 DOI: 10.1093/jacamr/dlab197 |
0.404 |
|
| 2022 |
Golden AR, Baxter M, Adam HJ, Martin I, Demczuk W, Mulvey MR, Karlowsky JA, Zhanel GG. PCV-15 and PPSV-23 coverage of invasive and respiratory tract Streptococcus pneumoniae, including MDR and XDR isolates: CANWARD 2007-20. The Journal of Antimicrobial Chemotherapy. PMID 35141750 DOI: 10.1093/jac/dkac034 |
0.349 |
|
| 2022 |
Lynch JP, Zhanel GG. Pseudomonas aeruginosa Pneumonia: Evolution of Antimicrobial Resistance and Implications for Therapy. Seminars in Respiratory and Critical Care Medicine. PMID 35062038 DOI: 10.1055/s-0041-1740109 |
0.423 |
|
| 2021 |
Taylor RM, Karlowsky JA, Baxter MR, Adam HJ, Walkty A, Lagacé-Wiens P, Zhanel GG. In vitro susceptibility of common bacterial pathogens causing respiratory tract infections in Canada to lefamulin, a new pleuromutilin. Journal of the Association of Medical Microbiology and Infectious Disease Canada = Journal Officiel De L'Association Pour La Microbiologie Medicale Et L'Infectiologie Canada. 6: 149-162. PMID 36341032 DOI: 10.3138/jammi-2020-0043 |
0.456 |
|
| 2021 |
Demczuk W, Martin I, Griffith A, Lefebvre B, McGeer A, Tyrrell GJ, Zhanel GG, Kus JV, Hoang L, Minion J, Van Caeseele P, Gad RR, Haldane D, Zahariadis G, Mead K, et al. Linear regression equations to predict β-lactam, macrolide, lincosamide and fluoroquinolone minimum inhibitory concentrations from molecular antimicrobial resistance determinants in . Antimicrobial Agents and Chemotherapy. AAC0137021. PMID 34662197 DOI: 10.1128/AAC.01370-21 |
0.404 |
|
| 2021 |
Karlowsky JA, Baxter MR, Golden AR, Adam HJ, Walkty A, Lagacé-Wiens PRS, Zhanel GG. Use of Fosfomycin Etest® to Determine Susceptibility of Clinical Isolates of Other Than , Non-Fermenting Gram-Negative Bacilli, and Gram-positive Cocci. Journal of Clinical Microbiology. JCM0163521. PMID 34495708 DOI: 10.1128/JCM.01635-21 |
0.311 |
|
| 2021 |
Golden AR, Karlowsky JA, Walkty A, Baxter MR, Denisuik AJ, McCracken M, Mulvey MR, Adam HJ, Bay D, Zhanel GG. Comparison of phenotypic antimicrobial susceptibility testing results and WGS-derived genotypic resistance profiles for a cohort of ESBL-producing Escherichia coli collected from Canadian hospitals: CANWARD 2007-18. The Journal of Antimicrobial Chemotherapy. PMID 34378044 DOI: 10.1093/jac/dkab268 |
0.453 |
|
| 2021 |
Karlowsky JA, Walkty A, Golden AR, Baxter MR, Denisuik AJ, McCracken M, Mulvey MR, Adam HJ, Zhanel GG. ESBL-positive Escherichia coli and Klebsiella pneumoniae isolates from across Canada: CANWARD surveillance study, 2007-18. The Journal of Antimicrobial Chemotherapy. PMID 34378029 DOI: 10.1093/jac/dkab269 |
0.376 |
|
| 2021 |
Slipski CJ, Jamieson-Datzkiw TR, Zhanel GG, Bay DC. Characterization of proteobacterial plasmid integron-encoded efflux pump sequence diversity and quaternary ammonium compound antiseptic selection in grown planktonically and as biofilms. Antimicrobial Agents and Chemotherapy. AAC0106921. PMID 34280018 DOI: 10.1128/AAC.01069-21 |
0.376 |
|
| 2021 |
Slipski CJ, Jamieson-Datzkiw TR, Zhanel GG, Bay DC. Characterization of proteobacterial plasmid integron-encoded efflux pump sequence diversity and quaternary ammonium compound antiseptic selection in grown planktonically and as biofilms. Antimicrobial Agents and Chemotherapy. AAC0106921. PMID 34280018 DOI: 10.1128/AAC.01069-21 |
0.376 |
|
| 2021 |
Walkty A, Karlowsky JA, Baxter MR, Adam HJ, Golden A, Lagace-Wiens P, Zhanel GG. In vitro activity of imipenem-relebactam against various resistance phenotypes/genotypes of Enterobacterales and Pseudomonas aeruginosa isolated from patients across Canada as part of the CANWARD study, 2016-2019. Diagnostic Microbiology and Infectious Disease. 101: 115418. PMID 34102373 DOI: 10.1016/j.diagmicrobio.2021.115418 |
0.458 |
|
| 2021 |
Gregorchuk BSJ, Reimer SL, Green KAC, Cartwright NH, Beniac DR, Hiebert SL, Booth TF, Chong PM, Westmacott GR, Zhanel GG, Bay DC. Phenotypic and Multi-Omics Characterization of K-12 Adapted to Chlorhexidine Identifies the Role of MlaA and Other Cell Envelope Alterations Regulated by Stress Inducible Pathways in CHX Resistance. Frontiers in Molecular Biosciences. 8: 659058. PMID 34095221 DOI: 10.3389/fmolb.2021.659058 |
0.355 |
|
| 2021 |
Lynch JP, Clark NM, Zhanel GG. Escalating Antimicrobial Resistance Among Enterobacteriaceae: Focus on Carbapenemases. Expert Opinion On Pharmacotherapy. PMID 33823714 DOI: 10.1080/14656566.2021.1904891 |
0.477 |
|
| 2021 |
Zhanel GG, Adam HJ, Baxter M, Lagace-Wiens PRS, Karlowsky JA. In vitro activity and resistance rates of topical antimicrobials fusidic acid, mupirocin and ozenoxacin against skin and soft tissue infection pathogens obtained across Canada (CANWARD 2007-18). The Journal of Antimicrobial Chemotherapy. PMID 33792700 DOI: 10.1093/jac/dkab098 |
0.36 |
|
| 2020 |
Hink RK, Adam HJ, Golden AR, Baxter M, Martin I, Nichol KA, Demczuk W, Mulvey MR, Karlowsky JA, Zhanel GG. Comparison of PCV-10 and PCV-13 vaccine coverage for invasive pneumococcal isolates obtained across Canadian geographic regions, SAVE 2011 to 2017. Diagnostic Microbiology and Infectious Disease. 99: 115282. PMID 33341491 DOI: 10.1016/j.diagmicrobio.2020.115282 |
0.374 |
|
| 2020 |
Zhanel GG, Deng C, Zelenitsky S, Lawrence CK, Adam HJ, Golden A, Berry L, Schweizer F, Zhanel MA, Irfan N, Bay D, Lagacé-Wiens P, Walkty A, Mandell L, Lynch JP, et al. Lefamulin: A Novel Oral and Intravenous Pleuromutilin for the Treatment of Community-Acquired Bacterial Pneumonia. Drugs. PMID 33247830 DOI: 10.1007/s40265-020-01443-4 |
0.329 |
|
| 2020 |
Milner KA, Bay DC, Alexander D, Walkty A, Karlowsky JA, Mulvey MR, Sharma MK, Zhanel GG. Identification and characterization of a novel FosA7 member from fosfomycin resistant clinical isolates from Canadian hospitals. Antimicrobial Agents and Chemotherapy. PMID 33077665 DOI: 10.1128/AAC.00865-20 |
0.412 |
|
| 2020 |
Slipski CJ, Jamieson TR, Zhanel GG, Bay DC. Riboswitch associated guanidinium selective efflux pumps frequently transmitted on proteobacterial plasmids increase biofilm tolerance to disinfectants. Journal of Bacteriology. PMID 32928929 DOI: 10.1128/Jb.00104-20 |
0.496 |
|
| 2020 |
Karlowsky JA, Lagacé-Wiens PRS, Laing NM, Baxter MR, Adam HJ, Zhanel GG. Susceptibility of Clinical Isolates of to Fosfomycin Measured by Four Testing Methods. Journal of Clinical Microbiology. PMID 32817224 DOI: 10.1128/Jcm.01306-20 |
0.432 |
|
| 2020 |
Zhanel GG, Zhanel MA, Karlowsky JA. Oral and Intravenous Fosfomycin for the Treatment of Complicated Urinary Tract Infections. The Canadian Journal of Infectious Diseases & Medical Microbiology = Journal Canadien Des Maladies Infectieuses Et De La Microbiologie Medicale. 2020: 8513405. PMID 32300381 DOI: 10.1155/2020/8513405 |
0.471 |
|
| 2020 |
Karlowsky JA, Adam HJ, Baxter MR, Dutka CW, Nichol KA, Laing NM, Golding GR, Zhanel GG. Antimicrobial susceptibility of Clostridioides difficile isolated from diarrhoeal stool specimens of Canadian patients: summary of results from the Canadian Clostridioides difficile (CAN-DIFF) surveillance study from 2013 to 2017. The Journal of Antimicrobial Chemotherapy. PMID 32294172 DOI: 10.1093/Jac/Dkaa118 |
0.459 |
|
| 2020 |
Golden AR, Adam HJ, Baxter M, Walkty A, Lagacé-Wiens P, Karlowsky JA, Zhanel GG. In Vitro Activity of Cefiderocol, a Novel Siderophore Cephalosporin, against Gram-Negative Bacilli Isolated from Patients in Canadian Intensive Care Units. Diagnostic Microbiology and Infectious Disease. 115012. PMID 32081522 DOI: 10.1016/J.Diagmicrobio.2020.115012 |
0.434 |
|
| 2020 |
Zhanel GG, Esquivel J, Zelenitsky S, Lawrence CK, Adam HJ, Golden A, Hink R, Berry L, Schweizer F, Zhanel MA, Bay D, Lagacé-Wiens PRS, Walkty AJ, Lynch JP, Karlowsky JA. Omadacycline: A Novel Oral and Intravenous Aminomethylcycline Antibiotic Agent. Drugs. PMID 31970713 DOI: 10.1007/S40265-020-01257-4 |
0.501 |
|
| 2020 |
Idowu T, Zhanel GG, Schweizer F. A Dimer, but not Monomer, of Tobramycin Potentiates Ceftolozane against MDR/XDR and Delays Resistance Development. Antimicrobial Agents and Chemotherapy. PMID 31907191 DOI: 10.1128/Aac.02055-19 |
0.579 |
|
| 2019 |
Walkty A, Karlowsky JA, Baxter MR, Adam HJ, Alexander D, Bay DC, Boyd D, McCracken M, Mulvey MR, Zhanel GG. Fosfomycin resistance mediated by fos genes remains rare among extended-spectrum beta-lactamase-producing Escherichia coli clinical isolates recovered from the urine of patients evaluated at Canadian hospitals (CANWARD, 2007-2017). Diagnostic Microbiology and Infectious Disease. 114962. PMID 31859022 DOI: 10.1016/J.Diagmicrobio.2019.114962 |
0.473 |
|
| 2019 |
Idowu T, Ammeter D, Rossong H, Zhanel GG, Schweizer FM. Homodimeric Tobramycin Adjuvant Repurposes Novobiocin as an Effective Antibacterial Agent against Gram-negative Bacteria. Journal of Medicinal Chemistry. PMID 31557020 DOI: 10.1021/Acs.Jmedchem.9B00876 |
0.54 |
|
| 2019 |
Lagacé-Wiens PRS, Adam HJ, Poutanen S, Baxter MR, Denisuik AJ, Golden AR, Nichol KA, Walkty A, Karlowsky JA, Mulvey MR, Golding G, Hoban DJ, Zhanel GG. Trends in antimicrobial resistance over 10 years among key bacterial pathogens from Canadian hospitals: results of the CANWARD study 2007-16. The Journal of Antimicrobial Chemotherapy. 74: iv22-iv31. PMID 31505648 DOI: 10.1093/Jac/Dkz284 |
0.538 |
|
| 2019 |
Denisuik AJ, Karlowsky JA, Adam HJ, Baxter MR, Lagacé-Wiens PRS, Mulvey MR, Hoban DJ, Zhanel GG. Dramatic rise in the proportion of ESBL-producing Escherichia coli and Klebsiella pneumoniae among clinical isolates identified in Canadian hospital laboratories from 2007 to 2016. The Journal of Antimicrobial Chemotherapy. 74: iv64-iv71. PMID 31505647 DOI: 10.1093/Jac/Dkz289 |
0.482 |
|
| 2019 |
Nichol KA, Adam HJ, Golding GR, Lagacé-Wiens PRS, Karlowsky JA, Hoban DJ, Zhanel GG. Characterization of MRSA in Canada from 2007 to 2016. The Journal of Antimicrobial Chemotherapy. 74: iv55-iv63. PMID 31505646 DOI: 10.1093/Jac/Dkz288 |
0.325 |
|
| 2019 |
Fuller J, Dingle TC, Bull A, Shokoples S, Laverdière M, Baxter MR, Adam HJ, Karlowsky JA, Zhanel GG. Species distribution and antifungal susceptibility of invasive Candida isolates from Canadian hospitals: results of the CANWARD 2011-16 study. The Journal of Antimicrobial Chemotherapy. 74: iv48-iv54. PMID 31505645 DOI: 10.1093/Jac/Dkz287 |
0.378 |
|
| 2019 |
Golden AR, Baxter MR, Davidson RJ, Martin I, Demczuk W, Mulvey MR, Karlowsky JA, Hoban DJ, Zhanel GG, Adam HJ. Comparison of antimicrobial resistance patterns in Streptococcus pneumoniae from respiratory and blood cultures in Canadian hospitals from 2007-16. The Journal of Antimicrobial Chemotherapy. 74: iv39-iv47. PMID 31505644 DOI: 10.1093/Jac/Dkz286 |
0.443 |
|
| 2019 |
McCracken MG, Adam HJ, Blondeau JM, Walkty AJ, Karlowsky JA, Hoban DJ, Zhanel GG, Mulvey MR. Characterization of carbapenem-resistant and XDR Pseudomonas aeruginosa in Canada: results of the CANWARD 2007-16 study. The Journal of Antimicrobial Chemotherapy. 74: iv32-iv38. PMID 31505643 DOI: 10.1093/Jac/Dkz285 |
0.584 |
|
| 2019 |
Zhanel GG, Adam HJ, Baxter MR, Fuller J, Nichol KA, Denisuik AJ, Golden AR, Hink R, Lagacé-Wiens PRS, Walkty A, Mulvey MR, Schweizer F, Bay D, Hoban DJ, Karlowsky JA, et al. 42936 pathogens from Canadian hospitals: 10 years of results (2007-16) from the CANWARD surveillance study. The Journal of Antimicrobial Chemotherapy. 74: iv5-iv21. PMID 31505641 DOI: 10.1093/Jac/Dkz283 |
0.436 |
|
| 2019 |
Ammeter D, Idowu T, Zhanel GG, Schweizer F. Development of a nebramine-cyclam conjugate as an antibacterial adjuvant to potentiate β-lactam antibiotics against multidrug-resistant P. aeruginosa. The Journal of Antibiotics. PMID 31420586 DOI: 10.1038/S41429-019-0221-9 |
0.473 |
|
| 2019 |
Karlowsky JA, Steenbergen J, Zhanel GG. Microbiology and Preclinical Review of Omadacycline. Clinical Infectious Diseases : An Official Publication of the Infectious Diseases Society of America. 69: S6-S15. PMID 31367743 DOI: 10.1093/Cid/Ciz395 |
0.543 |
|
| 2019 |
Domalaon R, Ammeter D, Brizuela M, Gorityala BK, Zhanel GG, Schweizer F. Repurposed Antimicrobial Combination Therapy: Tobramycin-Ciprofloxacin Hybrid Augments Activity of the Anticancer Drug Mitomycin C Against Multidrug-Resistant Gram-Negative Bacteria. Frontiers in Microbiology. 10: 1556. PMID 31354660 DOI: 10.3389/Fmicb.2019.01556 |
0.495 |
|
| 2019 |
Idowu T, Ammeter D, Arthur G, Zhanel GG, Schweizer F. Potentiation of β-lactam antibiotics and β-lactam/β-lactamase inhibitor combinations against MDR and XDR Pseudomonas aeruginosa using non-ribosomal tobramycin-cyclam conjugates. The Journal of Antimicrobial Chemotherapy. PMID 31139830 DOI: 10.1093/Jac/Dkz228 |
0.394 |
|
| 2019 |
Yang X, Ammeter D, Idowu T, Domalaon R, Brizuela M, Okunnu O, Bi L, Guerrero YA, Zhanel GG, Kumar A, Schweizer F. Amphiphilic nebramine-based hybrids Rescue legacy antibiotics from intrinsic resistance in multidrug-resistant Gram-negative bacilli. European Journal of Medicinal Chemistry. 175: 187-200. PMID 31078866 DOI: 10.1016/J.Ejmech.2019.05.003 |
0.544 |
|
| 2019 |
Berry L, Domalaon R, Brizuela M, Zhanel GG, Schweizer F. Polybasic peptide-levofloxacin conjugates potentiate fluoroquinolones and other classes of antibiotics against multidrug-resistant Gram-negative bacteria. Medchemcomm. 10: 517-527. PMID 31057731 DOI: 10.1039/C9Md00051H |
0.498 |
|
| 2019 |
Karlowsky JA, Lagacé-Wiens PRS, Adam HJ, Baxter MR, Laing NM, Walkty AJ, Zhanel GG. In Vitro Susceptibility of Urinary Isolates of Escherichia coli to First- and Second-Line Empirically Prescribed Oral Antimicrobial Agents: CANWARD Surveillance Study Results for Canadian Outpatients from 2007 to 2016. International Journal of Antimicrobial Agents. PMID 31034938 DOI: 10.1016/J.Ijantimicag.2019.04.012 |
0.555 |
|
| 2019 |
Domalaon R, Okunnu O, Zhanel GG, Schweizer F. Synergistic combinations of anthelmintic salicylanilides oxyclozanide, rafoxanide, and closantel with colistin eradicates multidrug-resistant colistin-resistant Gram-negative bacilli. The Journal of Antibiotics. PMID 31028351 DOI: 10.1038/S41429-019-0186-8 |
0.593 |
|
| 2019 |
Idowu T, Arthur G, Zhanel GG, Schweizer F. Heterodimeric Rifampicin-Tobramycin conjugates break intrinsic resistance of Pseudomonas aeruginosa to doxycycline and chloramphenicol in vitro and in a Galleria mellonella in vivo model. European Journal of Medicinal Chemistry. 174: 16-32. PMID 31022550 DOI: 10.1016/J.Ejmech.2019.04.034 |
0.519 |
|
| 2019 |
Domalaon R, De Silva PM, Kumar A, Zhanel GG, Schweizer F. The Anthelmintic Drug Niclosamide Synergizes with Colistin and Reverses Colistin Resistance in Gram-Negative Bacilli. Antimicrobial Agents and Chemotherapy. 63. PMID 30917988 DOI: 10.1128/Aac.02574-18 |
0.584 |
|
| 2019 |
Boyd DA, Lisboa LF, Rennie R, Zhanel GG, Dingle TC, Mulvey MR. Identification of a novel metallo-β-lactamase, CAM-1, in clinical Pseudomonas aeruginosa isolates from Canada. The Journal of Antimicrobial Chemotherapy. PMID 30789204 DOI: 10.1093/Jac/Dkz066 |
0.387 |
|
| 2019 |
Zhanel GG, Golden AR, Zelenitsky S, Wiebe K, Lawrence CK, Adam HJ, Idowu T, Domalaon R, Schweizer F, Zhanel MA, Lagacé-Wiens PRS, Walkty AJ, Noreddin A, Lynch Iii JP, Karlowsky JA. Cefiderocol: A Siderophore Cephalosporin with Activity Against Carbapenem-Resistant and Multidrug-Resistant Gram-Negative Bacilli. Drugs. PMID 30712199 DOI: 10.1007/S40265-019-1055-2 |
0.542 |
|
| 2019 |
Zelenitsky SA, Beahm NP, Iacovides H, Ariano RE, Zhanel G. Limitations of ceftriaxone compared with cefazolin against MSSA: an integrated pharmacodynamic analysis. The Journal of Antimicrobial Chemotherapy. 73: 1888-1894. PMID 29635472 DOI: 10.1093/Jac/Dky120 |
0.37 |
|
| 2019 |
Zhanel GG. Influence of Pharmacokinetic and Pharmacodynamic Principles on Antibiotic Selection. Current Infectious Disease Reports. 3: 29-34. PMID 11177728 DOI: 10.1007/S11908-001-0056-X |
0.528 |
|
| 2019 |
Zhanel GG, Karlowsky JA. Ribosomal Resistance: Emerging Problems and Potential Solutions. Current Infectious Disease Reports. 1: 458-463. PMID 11095824 DOI: 10.1007/S11908-999-0059-6 |
0.572 |
|
| 2019 |
Walkty A, Adam H, Baxter M, Lagace-Wiens P, Karlowsky J, Zhanel G. 708. In Vitro Activity of Plazomicin vs. Clinical Isolates of Gram-Negative Bacilli, Including Aminoglycoside Nonsusceptible and Multidrug-Resistant Subsets, Recovered from Patients Across Canada as Part of the CANWARD study, 2011–2018 Open Forum Infectious Diseases. 6: S319-S319. DOI: 10.1093/Ofid/Ofz360.776 |
0.569 |
|
| 2019 |
Walkty A, Adam H, Baxter M, Henni A, Lagace-Wiens P, Karlowsky J, Zhanel G. 128. Adequacy of Commonly Prescribed Antimicrobials for Empiric Coverage of Gram-Negative Bacterial Pathogens Recovered from the Bloodstream of Patients Attending Emergency Rooms in Canada: Analysis of Data from the CANWARD Study, 2007 to 2018 Open Forum Infectious Diseases. 6: S93-S93. DOI: 10.1093/Ofid/Ofz360.203 |
0.513 |
|
| 2018 |
Walkty A, Karlowsky JA, Baxter MR, Adam HJ, Boyd D, Bharat A, Mulvey MR, Charles M, Bergevin M, Zhanel GG. Frequency of 16S ribosomal RNA methyltransferase detection among Escherichia coli and Klebsiella pneumoniae clinical isolates obtained from patients in Canadian hospitals (CANWARD, 2013-2017). Diagnostic Microbiology and Infectious Disease. PMID 30638654 DOI: 10.1016/J.Diagmicrobio.2018.12.005 |
0.454 |
|
| 2018 |
Denisuik AJ, Garbutt LA, Golden AR, Adam HJ, Baxter M, Nichol KA, Lagacé-Wiens P, Walkty AJ, Karlowsky JA, Hoban DJ, Mulvey MR, Zhanel GG. Antimicrobial-resistant pathogens in Canadian ICUs: results of the CANWARD 2007 to 2016 study. The Journal of Antimicrobial Chemotherapy. PMID 30500898 DOI: 10.1093/Jac/Dky477 |
0.544 |
|
| 2018 |
Karlowsky JA, Adam HJ, Baxter MR, Denisuik AJ, Lagacé-Wiens PRS, Walkty AJ, Puttagunta S, Dunne MW, Zhanel GG. Activity of Sulopenem, an Oral Penem, Against Urinary Isolates of . Antimicrobial Agents and Chemotherapy. PMID 30397056 DOI: 10.1128/Aac.01832-18 |
0.519 |
|
| 2018 |
Zhanel G, Critchley I, Lin LY, Alvandi N. Microbiological Profile of Sarecycline: A Novel Targeted Spectrum Tetracycline for the Treatment of Acne Vulgaris. Antimicrobial Agents and Chemotherapy. PMID 30397052 DOI: 10.1128/Aac.01297-18 |
0.503 |
|
| 2018 |
Domalaon R, Brizuela M, Eisner B, Findlay B, Zhanel GG, Schweizer F. Dilipid ultrashort cationic lipopeptides as adjuvants for chloramphenicol and other conventional antibiotics against Gram-negative bacteria. Amino Acids. PMID 30392097 DOI: 10.1007/S00726-018-2673-9 |
0.491 |
|
| 2018 |
Walkty A, Karlowsky JA, Baxter MR, Adam HJ, Zhanel GG. Activity of Plazomicin against Gram-negative and Gram-positive Bacterial Pathogens Isolated from Patients in Canadian Hospitals from 2013 to 2017: CANWARD Surveillance Study. Antimicrobial Agents and Chemotherapy. PMID 30373806 DOI: 10.1128/Aac.02068-18 |
0.581 |
|
| 2018 |
Domalaon R, Berry L, Tays Q, Zhanel GG, Schweizer F. Development of dilipid polymyxins: Investigation on the effect of hydrophobicity through its fatty acyl component. Bioorganic Chemistry. 80: 639-648. PMID 30053708 DOI: 10.1016/J.Bioorg.2018.07.018 |
0.458 |
|
| 2018 |
Zhanel GG, Zhanel MA, Karlowsky JA. Intravenous Fosfomycin: An Assessment of Its Potential for Use in the Treatment of Systemic Infections in Canada. The Canadian Journal of Infectious Diseases & Medical Microbiology = Journal Canadien Des Maladies Infectieuses Et De La Microbiologie Medicale. 2018: 8912039. PMID 30046362 DOI: 10.1155/2018/8912039 |
0.554 |
|
| 2018 |
Golden AR, Adam HJ, Karlowsky JA, Baxter M, Nichol KA, Martin I, Demczuk W, Van Caeseele P, Gubbay JB, Lefebvre B, Levett PN, Zahariadis G, Haldane D, Gad R, German G, ... ... Zhanel GG, et al. Molecular characterization of predominant Streptococcus pneumoniae serotypes causing invasive infections in Canada: the SAVE study, 2011-15. The Journal of Antimicrobial Chemotherapy. 73: vii20-vii31. PMID 29982573 DOI: 10.1093/Jac/Dky157 |
0.357 |
|
| 2018 |
Adam HJ, Golden AR, Karlowsky JA, Baxter MR, Nichol KA, Martin I, Demczuk W, Mulvey MR, Gilmour MW, Hoban DJ, Zhanel GG. Analysis of multidrug resistance in the predominant Streptococcus pneumoniae serotypes in Canada: the SAVE study, 2011-15. The Journal of Antimicrobial Chemotherapy. 73: vii12-vii19. PMID 29982572 DOI: 10.1093/Jac/Dky158 |
0.551 |
|
| 2018 |
Zhanel GG, Adam HJ. Introduction to the SAVE study (2011-15): Streptococcus pneumoniae serotyping and antimicrobial susceptibility: Assessment for Vaccine Efficacy in Canada after the introduction of PCV-13. The Journal of Antimicrobial Chemotherapy. 73: vii2-vii4. PMID 29982571 DOI: 10.1093/Jac/Dky155 |
0.493 |
|
| 2018 |
Karlowsky JA, Adam HJ, Golden AR, Baxter MR, Nichol KA, Martin I, Demczuk W, Mulvey MR, Gilmour MW, Hoban DJ, Zhanel GG. Antimicrobial susceptibility testing of invasive isolates of Streptococcus pneumoniae from Canadian patients: the SAVE study, 2011-15. The Journal of Antimicrobial Chemotherapy. 73: vii5-vii11. PMID 29982570 DOI: 10.1093/Jac/Dky156 |
0.451 |
|
| 2018 |
Demczuk WHB, Martin I, Desai S, Griffith A, Caron-Poulin L, Lefebvre B, McGeer A, Tyrrell GJ, Zhanel GG, Gubbay J, Hoang L, Levett PN, Van Caeseele P, Raafat Gad R, Haldane D, et al. Serotype distribution of invasive Streptococcus pneumoniae in adults 65 years of age and over after the introduction of childhood 13-valent pneumococcal conjugate vaccination programs in Canada, 2010-2016. Vaccine. PMID 29937245 DOI: 10.1016/J.Vaccine.2018.06.018 |
0.314 |
|
| 2018 |
Yang X, Domalaon R, Lyu Y, Zhanel GG, Schweizer F. Tobramycin-Linked Efflux Pump Inhibitor Conjugates Synergize Fluoroquinolones, Rifampicin and Fosfomycin against Multidrug-Resistant . Journal of Clinical Medicine. 7. PMID 29932132 DOI: 10.3390/Jcm7070158 |
0.506 |
|
| 2018 |
Zhanel GG, Zhanel MA, Karlowsky JA. Oral Fosfomycin for the Treatment of Acute and Chronic Bacterial Prostatitis Caused by Multidrug-Resistant . The Canadian Journal of Infectious Diseases & Medical Microbiology = Journal Canadien Des Maladies Infectieuses Et De La Microbiologie Medicale. 2018: 1404813. PMID 29666664 DOI: 10.1155/2018/1404813 |
0.438 |
|
| 2018 |
Domalaon R, Idowu T, Zhanel GG, Schweizer F. Antibiotic Hybrids: the Next Generation of Agents and Adjuvants against Gram-Negative Pathogens? Clinical Microbiology Reviews. 31. PMID 29540434 DOI: 10.1128/Cmr.00077-17 |
0.539 |
|
| 2018 |
Karlowsky JA, Adam HJ, Kosowan T, Baxter MR, Nichol KA, Laing NM, Golding G, Zhanel GG. PCR ribotyping and antimicrobial susceptibility testing of isolates of Clostridium difficile cultured from toxin-positive diarrheal stools of patients receiving medical care in Canadian hospitals: the Canadian Clostridium difficile Surveillance Study (CAN-DIFF) 2013-2015. Diagnostic Microbiology and Infectious Disease. PMID 29456070 DOI: 10.1016/J.Diagmicrobio.2018.01.017 |
0.537 |
|
| 2018 |
Domalaon R, Sanchak Y, Koskei LC, Lyu Y, Zhanel GG, Arthur G, Schweizer F. Short proline-rich lipopeptide potentiates minocycline and rifampicin against multidrug- and extensively drug-resistant. Antimicrobial Agents and Chemotherapy. PMID 29437631 DOI: 10.1128/Aac.02374-17 |
0.423 |
|
| 2018 |
Walkty A, Adam HJ, Baxter M, Lagace-Wiens P, Karlowsky J, Hoban D, Zhanel G. 2383. In Vitro Activity of Ceftolozane–Tazobactam in Comparison With Ceftazidime–Avibactam vs. Antimicrobial Non-Susceptible Pseudomonas aeruginosa Clinical Isolates, Including Multidrug-Resistant and Extensively Drug-Resistant Subsets: CANWARD, 2007–2017 Open Forum Infectious Diseases. 5: S710-S710. DOI: 10.1093/Ofid/Ofy210.2036 |
0.575 |
|
| 2017 |
Zhanel GG, Baxter MR, Adam HJ, Sutcliffe J, Karlowsky JA. In vitro activity of eravacycline against 2213 Gram-negative and 2424 Gram-positive bacterial pathogens isolated in Canadian hospital laboratories: CANWARD surveillance study 2014-2015. Diagnostic Microbiology and Infectious Disease. PMID 29338931 DOI: 10.1016/J.Diagmicrobio.2017.12.013 |
0.463 |
|
| 2017 |
Walkty A, Adam H, Baxter M, Lagacé-Wiens P, Karlowsky JA, Hoban DJ, Zhanel GG. In vitro activity of ceftolozane/tazobactam versus antimicrobial non-susceptible Pseudomonas aeruginosa clinical isolates including MDR and XDR isolates obtained from across Canada as part of the CANWARD study, 2008-16. The Journal of Antimicrobial Chemotherapy. PMID 29244121 DOI: 10.1093/Jac/Dkx468 |
0.495 |
|
| 2017 |
Zhanel GG, Lawrence CK, Adam H, Schweizer F, Zelenitsky S, Zhanel M, Lagacé-Wiens PRS, Walkty A, Denisuik A, Golden A, Gin AS, Hoban DJ, Lynch JP, Karlowsky JA. Imipenem-Relebactam and Meropenem-Vaborbactam: Two Novel Carbapenem-β-Lactamase Inhibitor Combinations. Drugs. PMID 29230684 DOI: 10.1007/S40265-017-0851-9 |
0.465 |
|
| 2017 |
Slipski CJ, Zhanel GG, Bay DC. Biocide Selective TolC-Independent Efflux Pumps in Enterobacteriaceae. The Journal of Membrane Biology. PMID 29063140 DOI: 10.1007/S00232-017-9992-8 |
0.561 |
|
| 2017 |
Domalaon R, Yang X, Lyu Y, Zhanel GG, Schweizer FM. Polymyxin B3 - tobramycin hybrids with Pseudomonas aeruginosa-selective antibacterial activity and strong potentiation of rifampicin, minocycline and vancomycin. Acs Infectious Diseases. PMID 29045123 DOI: 10.1021/Acsinfecdis.7B00145 |
0.573 |
|
| 2017 |
Lynch JP, Zhanel GG, Clark NM. Emergence of Antimicrobial Resistance among Pseudomonas aeruginosa: Implications for Therapy. Seminars in Respiratory and Critical Care Medicine. 38: 326-345. PMID 28578556 DOI: 10.1055/S-0037-1602583 |
0.528 |
|
| 2017 |
Lynch JP, Zhanel GG, Clark NM. Infections Due to Acinetobacter baumannii in the ICU: Treatment Options. Seminars in Respiratory and Critical Care Medicine. 38: 311-325. PMID 28578555 DOI: 10.1055/S-0037-1599225 |
0.571 |
|
| 2017 |
Demczuk WHB, Martin I, Hoang L, Van Caeseele P, Lefebvre B, Horsman G, Haldane D, Gubbay J, Ratnam S, German G, Daley Bernier J, Strudwick L, McGeer A, Zhanel GG, Van Domselaar G, et al. Phylogenetic analysis of emergent Streptococcus pneumoniae serotype 22F causing invasive pneumococcal disease using whole genome sequencing. Plos One. 12: e0178040. PMID 28531208 DOI: 10.1371/Journal.Pone.0178040 |
0.475 |
|
| 2017 |
Lagacé-Wiens PRS, Adam HJ, Laing NM, Baxter MR, Martin I, Mulvey MR, Karlowsky JA, Hoban DJ, Zhanel GG. Antimicrobial susceptibility of clinical isolates of Neisseria gonorrhoeae to alternative antimicrobials with therapeutic potential. The Journal of Antimicrobial Chemotherapy. PMID 28505331 DOI: 10.1093/Jac/Dkx147 |
0.446 |
|
| 2017 |
Zhanel GG, Parkinson K, Higgins S, Denisuik A, Adam H, Pitout J, Noreddin A, Karlowsky JA. Pharmacodynamic activity of fosfomycin simulating urinary concentrations achieved after a single 3-g oral dose versus Escherichia coli using an in vitro model. Diagnostic Microbiology and Infectious Disease. PMID 28483306 DOI: 10.1016/J.Diagmicrobio.2017.04.007 |
0.431 |
|
| 2017 |
Lyu Y, Yang X, Goswami S, Gorityala BK, Idowu T, Domalaon R, Zhanel GG, Shan A, Schweizer FM. Amphiphilic tobramycin-lysine conjugates sensitize multidrug resistant Gram-negative bacteria to rifampicin and minocycline. Journal of Medicinal Chemistry. PMID 28409644 DOI: 10.1021/Acs.Jmedchem.6B01742 |
0.561 |
|
| 2017 |
Yang X, Goswami S, Gorityala BK, Domalaon R, Lyu Y, Kumar A, Zhanel GG, Schweizer FM. A tobramycin vector enhances synergy and efficacy of efflux pump inhibitors against multidrug-resistant Gram-negative bacteria. Journal of Medicinal Chemistry. PMID 28399372 DOI: 10.1021/Acs.Jmedchem.7B00156 |
0.568 |
|
| 2017 |
Walkty A, Lagace-Wiens P, Adam H, Baxter M, Karlowsky J, Mulvey MR, McCracken M, Zhanel GG. Antimicrobial susceptibility of 2906 Pseudomonasaeruginosa clinical isolates obtained from patients in Canadian hospitals over a period of 8 years: Results of the Canadian Ward surveillance study (CANWARD), 2008-2015. Diagnostic Microbiology and Infectious Disease. 87: 60-63. PMID 28336136 DOI: 10.1016/J.Diagmicrobio.2016.10.003 |
0.577 |
|
| 2017 |
Perrault L, Dahan S, Iliza AC, LeLorier J, Zhanel GG. Cost-Effectiveness Analysis of Fosfomycin for Treatment of Uncomplicated Urinary Tract Infections in Ontario. The Canadian Journal of Infectious Diseases & Medical Microbiology = Journal Canadien Des Maladies Infectieuses Et De La Microbiologie Medicale. 2017: 6362804. PMID 28316632 DOI: 10.1155/2017/6362804 |
0.394 |
|
| 2017 |
Karlowsky JA, Walkty AJ, Baxter MR, Arhin FF, Moeck G, Adam HJ, Zhanel GG. In vitro activity of Oritavancin against gram-positive pathogens isolated in Canadian hospital laboratories from 2011 to 2015. Diagnostic Microbiology and Infectious Disease. PMID 28159446 DOI: 10.1016/J.Diagmicrobio.2017.01.006 |
0.559 |
|
| 2017 |
Walkty A, Adam HJ, Baxter M, Lagace-Wiens P, Karlowsky J, Hoban D, Zhanel G. In Vitro Activity of Ceftolozane-Tazobactam vs. Antimicrobial Non-Susceptible Pseudomonas aeruginosa Clinical Isolates Obtained from Across Canada as Part of the CANWARD Study, 2008–2016 Open Forum Infectious Diseases. 4: S372-S372. DOI: 10.1093/Ofid/Ofx163.913 |
0.497 |
|
| 2017 |
Walkty A, Baxter M, Adam HJ, Lagace-Wiens P, Karlowsky J, Zhanel G. In Vitro Activity of Newer Antimicrobials and Relevant Comparators Vs. 349 Stenotrophomonas maltophilia Clinical Isolates Obtained from Patients in Canadian Hospitals (CANWARD, 2011–2016) Open Forum Infectious Diseases. 4: S367-S368. DOI: 10.1093/Ofid/Ofx163.899 |
0.437 |
|
| 2016 |
Walkty A, Karlowsky JA, Adam HJ, Lagacé-Wiens P, Baxter M, Mulvey MR, McCracken M, Poutanen SM, Roscoe D, Zhanel GG. Frequency of MCR-1-mediated colistin resistance among Escherichia coli clinical isolates obtained from patients in Canadian hospitals (CANWARD 2008-2015). Cmaj Open. 4: E641-E645. PMID 28018876 DOI: 10.9778/cmajo.20160080 |
0.507 |
|
| 2016 |
Zhanel GG, Hartel E, Adam H, Zelenitsky S, Zhanel MA, Golden A, Schweizer F, Gorityala B, Lagacé-Wiens PR, Walkty AJ, Gin AS, Hoban DJ, Lynch JP, Karlowsky JA. Solithromycin: A Novel Fluoroketolide for the Treatment of Community-Acquired Bacterial Pneumonia. Drugs. PMID 27909995 DOI: 10.1007/S40265-016-0667-Z |
0.432 |
|
| 2016 |
Clark NM, Zhanel GG, Lynch JP. Emergence of antimicrobial resistance among Acinetobacter species: a global threat. Current Opinion in Critical Care. PMID 27552304 DOI: 10.1097/Mcc.0000000000000337 |
0.479 |
|
| 2016 |
Gorityala BK, Guchhait G, Goswami S, Fernando DM, Kumar A, Zhanel GG, Schweizer FM. Hybrid antibiotic overcomes resistance in P. aeruginosa by enhancing outer membrane penetration and reducing efflux. Journal of Medicinal Chemistry. PMID 27524179 DOI: 10.1021/Acs.Jmedchem.6B00867 |
0.494 |
|
| 2016 |
Del Rosso JQ, Webster GF, Rosen T, Thiboutot D, Leyden JJ, Gallo R, Walker C, Zhanel G, Eichenfield L. Status Report from the Scientific Panel on Antibiotic Use in Dermatology of the American Acne and Rosacea Society: Part 1: Antibiotic Prescribing Patterns, Sources of Antibiotic Exposure, Antibiotic Consumption and Emergence of Antibiotic Resistance, Impact of Alterations in Antibiotic Prescribing, and Clinical Sequelae of Antibiotic Use. The Journal of Clinical and Aesthetic Dermatology. 9: 18-24. PMID 27462384 |
0.399 |
|
| 2016 |
Del Rosso JQ, Rosen T, Thiboutot D, Webster GF, Gallo RL, Leyden JJ, Walker C, Zhanel G, Eichenfield L. Status Report from the Scientific Panel on Antibiotic Use in Dermatology of the American Acne and Rosacea Society: Part 3: Current Perspectives on Skin and Soft Tissue Infections with Emphasis on Methicillin-resistant Staphylococcus aureus, Commonly Encountered Scenarios when Antibiotic Use May Not Be Needed, and Concluding Remarks on Rational Use of Antibiotics in Dermatology. The Journal of Clinical and Aesthetic Dermatology. 9: 17-24. PMID 27386047 |
0.486 |
|
| 2016 |
Zhanel GG, Walkty AJ, Karlowsky JA. Fosfomycin: A First-Line Oral Therapy for Acute Uncomplicated Cystitis. The Canadian Journal of Infectious Diseases & Medical Microbiology = Journal Canadien Des Maladies Infectieuses Et De La Microbiologie MéDicale. 2016: 2082693. PMID 27366158 DOI: 10.1155/2016/2082693 |
0.504 |
|
| 2016 |
Zhanel GG, Del Rosso JQ. Activity of Dapsone versus Community and Hospital Pathogens from the CANWARD Study. The Journal of Clinical and Aesthetic Dermatology. 9: 42-7. PMID 27354888 |
0.341 |
|
| 2016 |
Golden AR, Adam HJ, Zhanel GG. Invasive Streptococcus pneumoniae in Canada, 2011-2014: Characterization of new candidate 15-valent pneumococcal conjugate vaccine serotypes 22F and 33F. Vaccine. PMID 27085174 DOI: 10.1016/J.Vaccine.2016.03.058 |
0.398 |
|
| 2016 |
Zhanel GG, Karlowsky JA. Kisameet Clay Isolated from the Central Coast of British Columbia, Canada, Demonstrates Broad-Spectrum Antimicrobial Activity. Mbio. 7. PMID 26956585 DOI: 10.1128/Mbio.00169-16 |
0.542 |
|
| 2016 |
Zhanel GG, Cheung D, Adam H, Zelenitsky S, Golden A, Schweizer F, Gorityala B, Lagacé-Wiens PR, Walkty A, Gin AS, Hoban DJ, Karlowsky JA. Review of Eravacycline, a Novel Fluorocycline Antibacterial Agent. Drugs. 76: 567-88. PMID 26863149 DOI: 10.1007/S40265-016-0545-8 |
0.406 |
|
| 2016 |
Domalaon R, Zhanel GG, Schweizer F. Short Antimicrobial Peptides and Peptide Scaffolds as Promising Antibacterial Agents. Current Topics in Medicinal Chemistry. 16: 1217-30. PMID 26369812 DOI: 10.2174/1568026615666150915112459 |
0.377 |
|
| 2016 |
Zelenitsky S, Beahm N, Ariano R, Iacovides H, Zhanel G. Pharmacodynamics of Ceftriaxone and Alternatives as Outpatient Antimicrobial Therapy for Methicillin-Susceptible Staphylococcus aureus Infections Open Forum Infectious Diseases. 3. DOI: 10.1093/Ofid/Ofw172.149 |
0.456 |
|
| 2015 |
Zhanel GG, Walkty AJ, Karlowsky JA. Fidaxomicin: A novel agent for the treatment of Clostridium difficile infection. The Canadian Journal of Infectious Diseases & Medical Microbiology = Journal Canadien Des Maladies Infectieuses Et De La Microbiologie MéDicale / Ammi Canada. 26: 305-12. PMID 26744587 DOI: 10.1155/2015/934594 |
0.308 |
|
| 2015 |
Gorityala BK, Guchhait G, Fernando DM, Deo S, McKenna SA, Zhanel GG, Kumar A, Schweizer F. Adjuvants Based on Hybrid Antibiotics Overcome Resistance in Pseudomonas aeruginosa and Enhance Fluoroquinolone Efficacy. Angewandte Chemie (International Ed. in English). PMID 26610184 DOI: 10.1002/Anie.201508330 |
0.569 |
|
| 2015 |
Bharat A, Martin I, Zhanel GG, Mulvey MR. In vitro potency and combination testing of antimicrobial agents against Neisseria gonorrhoeae. Journal of Infection and Chemotherapy : Official Journal of the Japan Society of Chemotherapy. PMID 26603424 DOI: 10.1016/J.Jiac.2015.10.002 |
0.486 |
|
| 2015 |
Karlowsky JA, Nichol K, Zhanel GG. Telavancin: mechanisms of action, in vitro activity, and mechanisms of resistance. Clinical Infectious Diseases : An Official Publication of the Infectious Diseases Society of America. 61: S58-68. PMID 26316559 DOI: 10.1093/Cid/Civ534 |
0.586 |
|
| 2015 |
Zhanel GG, Wolter KD, Karlowsky JA. Clinical cure rates in subjects treated with azithromycin for community-acquired respiratory tract infections caused by azithromycin-susceptible or azithromycin-resistant Streptococcus pneumoniae: analysis of Phase 3 clinical trial data-authors' response. The Journal of Antimicrobial Chemotherapy. 70: 3170-1. PMID 26242414 DOI: 10.1093/jac/dkv234 |
0.317 |
|
| 2015 |
De Silva M, Ning C, Ghanbar S, Zhanel G, Logsetty S, Liu S, Kumar A. Evidence that a novel quaternary compound and its organic N-chloramine derivative do not select for resistant mutants of Pseudomonas aeruginosa. The Journal of Hospital Infection. PMID 26122622 DOI: 10.1016/J.Jhin.2015.05.009 |
0.479 |
|
| 2015 |
Mehrad B, Clark NM, Zhanel GG, Lynch JP. Antimicrobial resistance in hospital-acquired gram-negative bacterial infections. Chest. 147: 1413-21. PMID 25940252 DOI: 10.1378/Chest.14-2171 |
0.548 |
|
| 2015 |
Golden AR, Rosenthal M, Fultz B, Nichol KA, Adam HJ, Gilmour MW, Baxter MR, Hoban DJ, Karlowsky JA, Zhanel GG. Characterization of MDR and XDR Streptococcus pneumoniae in Canada, 2007-13. The Journal of Antimicrobial Chemotherapy. 70: 2199-202. PMID 25921512 DOI: 10.1093/Jac/Dkv107 |
0.537 |
|
| 2015 |
Simner PJ, Adam H, Baxter M, McCracken M, Golding G, Karlowsky JA, Nichol K, Lagacé-Wiens P, Gilmour MW, Hoban DJ, Zhanel GG. Epidemiology of Vancomycin-Resistant Enterococci in Canadian Hospitals (CANWARD Study, 2007 to 2013). Antimicrobial Agents and Chemotherapy. 59: 4315-7. PMID 25896693 DOI: 10.1128/Aac.00384-15 |
0.551 |
|
| 2015 |
Guchhait G, Altieri A, Gorityala B, Yang X, Findlay B, Zhanel GG, Mookherjee N, Schweizer F. Amphiphilic tobramycins with immunomodulatory properties. Angewandte Chemie (International Ed. in English). 54: 6278-82. PMID 25847672 DOI: 10.1002/Anie.201500598 |
0.347 |
|
| 2015 |
Denisuik AJ, Karlowsky JA, Denisuik T, Nichols WW, Keating TA, Adam HJ, Baxter M, Walkty A, Zhanel GG. In Vitro Activity of Ceftazidime-Avibactam against 338 Molecularly Characterized Gentamicin-Nonsusceptible Gram-Negative Clinical Isolates Obtained from Patients in Canadian Hospitals. Antimicrobial Agents and Chemotherapy. 59: 3623-6. PMID 25824208 DOI: 10.1128/Aac.00364-15 |
0.545 |
|
| 2015 |
Manges AR, Harel J, Masson L, Edens TJ, Portt A, Reid-Smith RJ, Zhanel GG, Kropinski AM, Boerlin P. Multilocus sequence typing and virulence gene profiles associated with Escherichia coli from human and animal sources. Foodborne Pathogens and Disease. 12: 302-10. PMID 25774654 DOI: 10.1089/Fpd.2014.1860 |
0.325 |
|
| 2015 |
Golden AR, Adam HJ, Gilmour MW, Baxter MR, Martin I, Nichol KA, Demczuk WH, Hoban DJ, Zhanel GG. Assessment of multidrug resistance, clonality and virulence in non-PCV-13 Streptococcus pneumoniae serotypes in Canada, 2011-13. The Journal of Antimicrobial Chemotherapy. 70: 1960-4. PMID 25761605 DOI: 10.1093/Jac/Dkv061 |
0.379 |
|
| 2015 |
Zhanel GG, Love R, Adam H, Golden A, Zelenitsky S, Schweizer F, Gorityala B, Lagacé-Wiens PR, Rubinstein E, Walkty A, Gin AS, Gilmour M, Hoban DJ, Lynch JP, Karlowsky JA. Tedizolid: a novel oxazolidinone with potent activity against multidrug-resistant gram-positive pathogens. Drugs. 75: 253-70. PMID 25673021 DOI: 10.1007/S40265-015-0352-7 |
0.533 |
|
| 2015 |
Jahan M, Zhanel GG, Sparling R, Holley RA. Horizontal transfer of antibiotic resistance from Enterococcus faecium of fermented meat origin to clinical isolates of E. faecium and Enterococcus faecalis. International Journal of Food Microbiology. 199: 78-85. PMID 25647243 DOI: 10.1016/J.Ijfoodmicro.2015.01.013 |
0.515 |
|
| 2015 |
Walkty A, Adam HJ, Baxter M, Lagace-Wiens P, Karlowsky J, Hoban D, Zhanel G. In Vitro Activity of Colistin (Polymyxin E) Versus 2541 Pseudomonas aeruginosa Clinical Isolates Obtained From Patients in Canadian Hospitals: Results of the CANWARD Study, 2008–2014 Open Forum Infectious Diseases. 2. DOI: 10.1093/Ofid/Ofv133.1376 |
0.427 |
|
| 2014 |
Karlowsky JA, Walkty AJ, Baxter MR, Adam HJ, Zhanel GG. In vitro activity of oritavancin against Gram-positive pathogens isolated in Canadian hospital laboratories from 2011 to 2013. Diagnostic Microbiology and Infectious Disease. 80: 311-5. PMID 25294303 DOI: 10.1016/J.Diagmicrobio.2014.09.003 |
0.545 |
|
| 2014 |
Fernando DM, Xu W, Loewen PC, Zhanel GG, Kumar A. Triclosan can select for an AdeIJK-overexpressing mutant of Acinetobacter baumannii ATCC 17978 that displays reduced susceptibility to multiple antibiotics. Antimicrobial Agents and Chemotherapy. 58: 6424-31. PMID 25136007 DOI: 10.1128/Aac.03074-14 |
0.497 |
|
| 2014 |
So W, Crandon JL, Zhanel GG, Nicolau DP. Comparison of in vivo and in vitro pharmacodynamics of a humanized regimen of 600 milligrams of Ceftaroline Fosamil every 12 hours against Staphylococcus aureus at initial inocula of 106 and 108 CFU per milliliter. Antimicrobial Agents and Chemotherapy. 58: 6931-3. PMID 25136006 DOI: 10.1128/Aac.03652-14 |
0.423 |
|
| 2014 |
Domalaon R, Yang X, O'Neil J, Zhanel GG, Mookherjee N, Schweizer F. Structure-activity relationships in ultrashort cationic lipopeptides: the effects of amino acid ring constraint on antibacterial activity. Amino Acids. 46: 2517-30. PMID 25069750 DOI: 10.1007/S00726-014-1806-Z |
0.337 |
|
| 2014 |
Zhanel GG, Wolter KD, Calciu C, Hogan P, Low DE, Weiss K, Karlowsky JA. Clinical cure rates in subjects treated with azithromycin for community-acquired respiratory tract infections caused by azithromycin-susceptible or azithromycin-resistant Streptococcus pneumoniae: analysis of Phase 3 clinical trial data. The Journal of Antimicrobial Chemotherapy. 69: 2835-40. PMID 24920652 DOI: 10.1093/Jac/Dku207 |
0.464 |
|
| 2014 |
Zhanel GG, Denisuik A, Vashisht S, Yachison C, Adam HJ, Hoban DJ. Pharmacodynamic activity of ertapenem versus genotypically characterized extended-spectrum β-lactamase (ESBL)-, KPC- or NDM-producing Escherichia coli with reduced susceptibility or resistance to ertapenem using an in vitro model. The Journal of Antimicrobial Chemotherapy. 69: 2448-52. PMID 24827891 DOI: 10.1093/Jac/Dku149 |
0.482 |
|
| 2014 |
Walkty A, Adam H, Baxter M, Denisuik A, Lagacé-Wiens P, Karlowsky JA, Hoban DJ, Zhanel GG. In vitro activity of plazomicin against 5,015 gram-negative and gram-positive clinical isolates obtained from patients in canadian hospitals as part of the CANWARD study, 2011-2012. Antimicrobial Agents and Chemotherapy. 58: 2554-63. PMID 24550325 DOI: 10.1128/Aac.02744-13 |
0.561 |
|
| 2014 |
Zhanel GG, Chung P, Adam H, Zelenitsky S, Denisuik A, Schweizer F, Lagacé-Wiens PR, Rubinstein E, Gin AS, Walkty A, Hoban DJ, Lynch JP, Karlowsky JA. Ceftolozane/tazobactam: a novel cephalosporin/β-lactamase inhibitor combination with activity against multidrug-resistant gram-negative bacilli. Drugs. 74: 31-51. PMID 24352909 DOI: 10.1007/S40265-013-0168-2 |
0.524 |
|
| 2014 |
Fani F, Leprohon P, Zhanel GG, Bergeron MG, Ouellette M. Genomic analyses of DNA transformation and penicillin resistance in Streptococcus pneumoniae clinical isolates. Antimicrobial Agents and Chemotherapy. 58: 1397-403. PMID 24342643 DOI: 10.1128/Aac.01311-13 |
0.494 |
|
| 2014 |
Salem AH, Zhanel GG, Ibrahim SA, Noreddin AM. Monte Carlo simulation analysis of ceftobiprole, dalbavancin, daptomycin, tigecycline, linezolid and vancomycin pharmacodynamics against intensive care unit-isolated methicillin-resistant Staphylococcus aureus. Clinical and Experimental Pharmacology & Physiology. 41: 437-43. PMID 24341387 DOI: 10.1111/1440-1681.12195 |
0.409 |
|
| 2014 |
Karlowsky JA, Denisuik AJ, Lagacé-Wiens PR, Adam HJ, Baxter MR, Hoban DJ, Zhanel GG. In Vitro activity of fosfomycin against Escherichia coli isolated from patients with urinary tract infections in Canada as part of the CANWARD surveillance study. Antimicrobial Agents and Chemotherapy. 58: 1252-6. PMID 24323476 DOI: 10.1128/Aac.02399-13 |
0.512 |
|
| 2014 |
Wierzbowski AK, Karlowsky JA, Adam HJ, Nichol KA, Hoban DJ, Zhanel GG. Evolution and molecular characterization of macrolide-resistant Streptococcus pneumoniae in Canada between 1998 and 2008. The Journal of Antimicrobial Chemotherapy. 69: 59-66. PMID 23970485 DOI: 10.1093/Jac/Dkt332 |
0.781 |
|
| 2014 |
Walkty A, Decorby M, Adam HJ, Lagacé-Wiens P, Karlowsky J, Hoban D, Zhanel G. 254In Vitro Activity of Ceftazidime in Combination with Avibactam vs 1825 Pseudomonas aeruginosa Clinical Isolates Obtained from across Canada as Part of the CANWARD Study, 2009-2013 Open Forum Infectious Diseases. 1: S109-S109. DOI: 10.1093/Ofid/Ofu052.120 |
0.444 |
|
| 2013 |
Fernando D, Zhanel G, Kumar A. Antibiotic resistance and expression of resistance-nodulation-division pump- and outer membrane porin-encoding genes in Acinetobacter species isolated from Canadian hospitals. The Canadian Journal of Infectious Diseases & Medical Microbiology = Journal Canadien Des Maladies Infectieuses Et De La Microbiologie MéDicale / Ammi Canada. 24: 17-21. PMID 24421787 DOI: 10.1155/2013/696043 |
0.568 |
|
| 2013 |
Karlowsky JA, Adam HJ, Baxter MR, Lagacé-Wiens PR, Walkty AJ, Hoban DJ, Zhanel GG. In vitro activity of ceftaroline-avibactam against gram-negative and gram-positive pathogens isolated from patients in Canadian hospitals from 2010 to 2012: results from the CANWARD surveillance study. Antimicrobial Agents and Chemotherapy. 57: 5600-11. PMID 23979759 DOI: 10.1128/Aac.01485-13 |
0.583 |
|
| 2013 |
Walkty A, Karlowsky JA, Adam H, Baxter M, Lagacé-Wiens P, Hoban DJ, Zhanel GG. In vitro activity of ceftolozane-tazobactam against Pseudomonas aeruginosa isolates obtained from patients in Canadian hospitals in the CANWARD study, 2007 to 2012. Antimicrobial Agents and Chemotherapy. 57: 5707-9. PMID 23939895 DOI: 10.1128/Aac.01404-13 |
0.524 |
|
| 2013 |
Lupien A, Billal DS, Fani F, Soualhine H, Zhanel GG, Leprohon P, Ouellette M. Genomic characterization of ciprofloxacin resistance in a laboratory-derived mutant and a clinical isolate of Streptococcus pneumoniae. Antimicrobial Agents and Chemotherapy. 57: 4911-9. PMID 23877698 DOI: 10.1128/Aac.00418-13 |
0.525 |
|
| 2013 |
Hoban DJ, Zhanel GG. Introduction to the CANWARD study (2007–11). The Journal of Antimicrobial Chemotherapy. 68: i3-5. PMID 23720829 DOI: 10.1093/Jac/Dkt021 |
0.53 |
|
| 2013 |
Zhanel GG, Adam HJ, Baxter MR, Fuller J, Nichol KA, Denisuik AJ, Lagacé-Wiens PR, Walkty A, Karlowsky JA, Schweizer F, Hoban DJ. Antimicrobial susceptibility of 22746 pathogens from Canadian hospitals: results of the CANWARD 2007-11 study. The Journal of Antimicrobial Chemotherapy. 68: i7-22. PMID 23587781 DOI: 10.1093/Jac/Dkt022 |
0.458 |
|
| 2013 |
Zelenitsky SA, Rubinstein E, Ariano RE, Zhanel GG. Integrating pharmacokinetics, pharmacodynamics and MIC distributions to assess changing antimicrobial activity against clinical isolates of Pseudomonas aeruginosa causing infections in Canadian hospitals (CANWARD). The Journal of Antimicrobial Chemotherapy. 68: i67-72. PMID 23587780 DOI: 10.1093/Jac/Dkt028 |
0.45 |
|
| 2013 |
Denisuik AJ, Lagacé-Wiens PR, Pitout JD, Mulvey MR, Simner PJ, Tailor F, Karlowsky JA, Hoban DJ, Adam HJ, Zhanel GG. Molecular epidemiology of extended-spectrum β-lactamase-, AmpC β-lactamase- and carbapenemase-producing Escherichia coli and Klebsiella pneumoniae isolated from Canadian hospitals over a 5 year period: CANWARD 2007-11. The Journal of Antimicrobial Chemotherapy. 68: i57-65. PMID 23587779 DOI: 10.1093/Jac/Dkt027 |
0.43 |
|
| 2013 |
Nichol KA, Adam HJ, Roscoe DL, Golding GR, Lagacé-Wiens PR, Hoban DJ, Zhanel GG. Changing epidemiology of methicillin-resistant Staphylococcus aureus in Canada. The Journal of Antimicrobial Chemotherapy. 68: i47-55. PMID 23587778 DOI: 10.1093/Jac/Dkt026 |
0.539 |
|
| 2013 |
Karlowsky JA, Adam HJ, Desjardins M, Lagacé-Wiens PR, Hoban DJ, Zhanel GG. Changes in fluoroquinolone resistance over 5 years (CANWARD 2007-11) in bacterial pathogens isolated in Canadian hospitals. The Journal of Antimicrobial Chemotherapy. 68: i39-46. PMID 23587777 DOI: 10.1093/Jac/Dkt025 |
0.555 |
|
| 2013 |
Adam HJ, Baxter MR, Davidson RJ, Rubinstein E, Fanella S, Karlowsky JA, Lagacé-Wiens PR, Hoban DJ, Zhanel GG. Comparison of pathogens and their antimicrobial resistance patterns in paediatric, adult and elderly patients in Canadian hospitals. The Journal of Antimicrobial Chemotherapy. 68: i31-7. PMID 23587776 DOI: 10.1093/Jac/Dkt024 |
0.5 |
|
| 2013 |
Lagacé-Wiens PR, Adam HJ, Low DE, Blondeau JM, Baxter MR, Denisuik AJ, Nichol KA, Walkty A, Karlowsky JA, Mulvey MR, Hoban DJ, Zhanel GG. Trends in antibiotic resistance over time among pathogens from Canadian hospitals: results of the CANWARD study 2007-11. The Journal of Antimicrobial Chemotherapy. 68: i23-9. PMID 23587775 DOI: 10.1093/Jac/Dkt023 |
0.53 |
|
| 2013 |
Zhanel GG, Lawson CD, Adam H, Schweizer F, Zelenitsky S, Lagacé-Wiens PR, Denisuik A, Rubinstein E, Gin AS, Hoban DJ, Lynch JP, Karlowsky JA. Ceftazidime-avibactam: a novel cephalosporin/β-lactamase inhibitor combination. Drugs. 73: 159-77. PMID 23371303 DOI: 10.1007/S40265-013-0013-7 |
0.481 |
|
| 2013 |
Lynch JP, Clark NM, Zhanel GG. Evolution of antimicrobial resistance among Enterobacteriaceae (focus on extended spectrum β-lactamases and carbapenemases). Expert Opinion On Pharmacotherapy. 14: 199-210. PMID 23321047 DOI: 10.1517/14656566.2013.763030 |
0.549 |
|
| 2013 |
Johnson JR, Tchesnokova V, Johnston B, Clabots C, Roberts PL, Billig M, Riddell K, Rogers P, Qin X, Butler-Wu S, Price LB, Aziz M, Nicolas-Chanoine MH, Debroy C, Robicsek A, ... ... Zhanel G, et al. Abrupt emergence of a single dominant multidrug-resistant strain of Escherichia coli. The Journal of Infectious Diseases. 207: 919-28. PMID 23288927 DOI: 10.1093/Infdis/Jis933 |
0.558 |
|
| 2012 |
Baudry-Simner PJ, Singh A, Karlowsky JA, Hoban DJ, Zhanel GG. Mechanisms of reduced susceptibility to ciprofloxacin in Escherichia coli isolates from Canadian hospitals. The Canadian Journal of Infectious Diseases & Medical Microbiology = Journal Canadien Des Maladies Infectieuses Et De La Microbiologie MéDicale / Ammi Canada. 23: e60-4. PMID 23997786 DOI: 10.1155/2012/569093 |
0.55 |
|
| 2012 |
Li L, Pu T, Zhanel G, Zhao N, Ens W, Liu S. New biocide with both N-chloramine and quaternary ammonium moieties exerts enhanced bactericidal activity. Advanced Healthcare Materials. 1: 609-20. PMID 23184796 DOI: 10.1002/Adhm.201200018 |
0.485 |
|
| 2012 |
Bera S, Dhondikubeer R, Findlay B, Zhanel GG, Schweizer F. Synthesis and antibacterial activities of amphiphilic neomycin B-based bilipid conjugates and fluorinated neomycin B-based lipids. Molecules (Basel, Switzerland). 17: 9129-41. PMID 22858839 DOI: 10.3390/Molecules17089129 |
0.341 |
|
| 2012 |
Findlay B, Szelemej P, Zhanel GG, Schweizer F. Guanidylation and tail effects in cationic antimicrobial lipopeptoids. Plos One. 7: e41141. PMID 22844435 DOI: 10.1371/Journal.Pone.0041141 |
0.463 |
|
| 2012 |
Dhondikubeer R, Bera S, Zhanel GG, Schweizer F. Antibacterial activity of amphiphilic tobramycin. The Journal of Antibiotics. 65: 495-8. PMID 22781280 DOI: 10.1038/Ja.2012.59 |
0.459 |
|
| 2012 |
Bowler LL, Zhanel GG, Ball TB, Saward LL. Mature Pseudomonas aeruginosa biofilms prevail compared to young biofilms in the presence of ceftazidime. Antimicrobial Agents and Chemotherapy. 56: 4976-9. PMID 22777043 DOI: 10.1128/Aac.00650-12 |
0.453 |
|
| 2012 |
Walkty A, Baxter M, Adam H, Karlowsky JA, Lagacé-Wiens P, Hoban DJ, Zhanel GG. Antimicrobial susceptibility of Pseudomonas aeruginosa isolates obtained from patients in Canadian hospitals: CANWARD 2008-2011. Diagnostic Microbiology and Infectious Disease. 73: 361-4. PMID 22694789 DOI: 10.1016/J.Diagmicrobio.2012.05.007 |
0.55 |
|
| 2012 |
Findlay B, Zhanel GG, Schweizer F. Investigating the antimicrobial peptide 'window of activity' using cationic lipopeptides with hydrocarbon and fluorinated tails. International Journal of Antimicrobial Agents. 40: 36-42. PMID 22578748 DOI: 10.1016/J.Ijantimicag.2012.03.013 |
0.317 |
|
| 2012 |
Embil JM, Kabani A, Zhanel G, Nicolle LE. Low prevalence of gastrointestinal colonization with antimicrobial-resistant bacteria in high risk units in a Canadian tertiary care centre. The Canadian Journal of Infectious Diseases = Journal Canadien Des Maladies Infectieuses. 7: 307-12. PMID 22514455 DOI: 10.1155/1996/636575 |
0.419 |
|
| 2012 |
Zhanel GG, Hoban DJ, Harding GK. Subinhibitory antimicrobial concentrations: A review of in vitro and in vivo data. The Canadian Journal of Infectious Diseases = Journal Canadien Des Maladies Infectieuses. 3: 193-201. PMID 22514370 DOI: 10.1155/1992/793607 |
0.444 |
|
| 2012 |
Zhanel GG, Lawson CD, Zelenitsky S, Findlay B, Schweizer F, Adam H, Walkty A, Rubinstein E, Gin AS, Hoban DJ, Lynch JP, Karlowsky JA. Comparison of the next-generation aminoglycoside plazomicin to gentamicin, tobramycin and amikacin. Expert Review of Anti-Infective Therapy. 10: 459-73. PMID 22512755 DOI: 10.1586/Eri.12.25 |
0.566 |
|
| 2012 |
Lagace-Wiens PR, Duncan S, Kimani J, Thiong'o A, Shafi J, McClelland S, Sanders EJ, Zhanel G, Muraguri N, Mehta SD. Emergence of fluoroquinolone resistance in Neisseria gonorrhoeae isolates from four clinics in three regions of Kenya. Sexually Transmitted Diseases. 39: 332-4. PMID 22504591 DOI: 10.1097/Olq.0B013E318248A85F |
0.515 |
|
| 2012 |
Johnson JR, Nicolas-Chanoine MH, DebRoy C, Castanheira M, Robicsek A, Hansen G, Weissman S, Urban C, Platell J, Trott D, Zhanel G, Clabots C, Johnston BD, Kuskowski MA. Comparison of Escherichia coli ST131 pulsotypes, by epidemiologic traits, 1967-2009. Emerging Infectious Diseases. 18: 598-607. PMID 22469129 DOI: 10.3201/Eid1804.111627 |
0.533 |
|
| 2012 |
Zhanel GG, Yachison C, Nichol K, Adam H, Noreddin AM, Hoban DJ, Karlowsky JA. Assessment of the activity of ceftaroline against clinical isolates of penicillin-intermediate and penicillin-resistant Streptococcus pneumoniae with elevated MICs of ceftaroline using an in vitro pharmacodynamic model. The Journal of Antimicrobial Chemotherapy. 67: 1706-11. PMID 22467630 DOI: 10.1093/Jac/Dks113 |
0.569 |
|
| 2012 |
Zhanel GG, Schweizer F, Karlowsky JA. Oritavancin: mechanism of action. Clinical Infectious Diseases : An Official Publication of the Infectious Diseases Society of America. 54: S214-9. PMID 22431851 DOI: 10.1093/Cid/Cir920 |
0.416 |
|
| 2012 |
Bergeron CR, Prussing C, Boerlin P, Daignault D, Dutil L, Reid-Smith RJ, Zhanel GG, Manges AR. Chicken as reservoir for extraintestinal pathogenic Escherichia coli in humans, Canada. Emerging Infectious Diseases. 18: 415-21. PMID 22377351 DOI: 10.3201/Eid1803.111099 |
0.368 |
|
| 2012 |
Zhanel GG, Nicolle LE, Gin AS, Karlowsky J, Kabani A, Hoban DJ. Ciprofloxacin or imipenem use correlates with resistance in Pseudomonas aeruginosa. The Canadian Journal of Infectious Diseases = Journal Canadien Des Maladies Infectieuses. 9: 382-6. PMID 22346558 DOI: 10.1155/1998/210742 |
0.548 |
|
| 2012 |
Johnson JR, Porter SB, Zhanel G, Kuskowski MA, Denamur E. Virulence of Escherichia coli clinical isolates in a murine sepsis model in relation to sequence type ST131 status, fluoroquinolone resistance, and virulence genotype. Infection and Immunity. 80: 1554-62. PMID 22311928 DOI: 10.1128/Iai.06388-11 |
0.528 |
|
| 2012 |
Karlowsky JA, Zhanel GG, Hammond GW, Rubinstein E, Wylie J, Du T, Mulvey MR, Alfa MJ. Multidrug-resistant North American pulsotype 2 Clostridium difficile was the predominant toxigenic hospital-acquired strain in the province of Manitoba, Canada, in 2006-2007. Journal of Medical Microbiology. 61: 693-700. PMID 22301615 DOI: 10.1099/Jmm.0.041053-0 |
0.49 |
|
| 2012 |
Findlay B, Zhanel GG, Schweizer F. Neomycin-phenolic conjugates: polycationic amphiphiles with broad-spectrum antibacterial activity, low hemolytic activity and weak serum protein binding. Bioorganic & Medicinal Chemistry Letters. 22: 1499-503. PMID 22285320 DOI: 10.1016/J.Bmcl.2012.01.025 |
0.397 |
|
| 2012 |
Adam HJ, Karlowsky JA, Nichol KA, Gilmour MW, Hoban DJ, Embree J, Zhanel GG. Baseline epidemiology of Streptococcus pneumoniae serotypes in Canada prior to the introduction of the 13-valent pneumococcal vaccine. Microbial Drug Resistance (Larchmont, N.Y.). 18: 176-82. PMID 22204595 DOI: 10.1089/Mdr.2011.0197 |
0.452 |
|
| 2012 |
Karlowsky JA, Walkty AJ, Adam HJ, Baxter MR, Hoban DJ, Zhanel GG. Prevalence of antimicrobial resistance among clinical isolates of Bacteroides fragilis group in Canada in 2010-2011: CANWARD surveillance study. Antimicrobial Agents and Chemotherapy. 56: 1247-52. PMID 22203594 DOI: 10.1128/Aac.05823-11 |
0.52 |
|
| 2011 |
Keel RA, Zhanel GG, Zelenitsky S, Nicolau DP. Pharmacodynamic profiling of antimicrobials against Gram-negative respiratory isolates from Canadian hospitals. The Canadian Journal of Infectious Diseases & Medical Microbiology = Journal Canadien Des Maladies Infectieuses Et De La Microbiologie MéDicale / Ammi Canada. 22: 132-6. PMID 23205024 DOI: 10.1155/2011/971701 |
0.399 |
|
| 2011 |
Noreddin AM, Elkhatib WF, Cunnion KM, Zhanel GG. Cumulative clinical experience from over a decade of use of levofloxacin in community-acquired pneumonia: critical appraisal and role in therapy. Drug, Healthcare and Patient Safety. 3: 59-68. PMID 22046107 DOI: 10.2147/Dhps.S15599 |
0.439 |
|
| 2011 |
Simner PJ, Hoban DJ, Lagacé-Wiens PR, Zhanel GG, Karlowsky JA. Fluoroquinolone resistance in Escherichia coli isolated from patients attending Canadian hospitals is associated with the ST131 clone. Diagnostic Microbiology and Infectious Disease. 71: 323-4. PMID 21889284 DOI: 10.1016/J.Diagmicrobio.2011.07.016 |
0.526 |
|
| 2011 |
Karlowsky JA, Lagacé-Wiens PR, Simner PJ, DeCorby MR, Adam HJ, Walkty A, Hoban DJ, Zhanel GG. Antimicrobial resistance in urinary tract pathogens in Canada from 2007 to 2009: CANWARD surveillance study. Antimicrobial Agents and Chemotherapy. 55: 3169-75. PMID 21537027 DOI: 10.1128/Aac.00066-11 |
0.585 |
|
| 2011 |
Zelenitsky S, Alkurdi N, Weber Z, Ariano R, Zhanel G. Preferential emergence of reduced vancomycin susceptibility in health care-associated methicillin-resistant Staphylococcus aureus isolates during continuous-infusion vancomycin therapy in an in vitro dynamic model. Antimicrobial Agents and Chemotherapy. 55: 3627-30. PMID 21502616 DOI: 10.1128/Aac.01472-10 |
0.543 |
|
| 2011 |
Zhanel GG, Rossnagel E, Nichol K, Cox L, Karlowsky JA, Zelenitsky S, Noreddin AM, Hoban DJ. Ceftaroline pharmacodynamic activity versus community-associated and healthcare-associated methicillin-resistant Staphylococcus aureus, heteroresistant vancomycin-intermediate S. aureus, vancomycin-intermediate S. aureus and vancomycin-resistant S. aureus using an in vitro model. The Journal of Antimicrobial Chemotherapy. 66: 1301-5. PMID 21429940 DOI: 10.1093/Jac/Dkr110 |
0.56 |
|
| 2011 |
Walkty A, DeCorby M, Lagacé-Wiens PR, Karlowsky JA, Hoban DJ, Zhanel GG. In vitro activity of ceftazidime combined with NXL104 versus Pseudomonas aeruginosa isolates obtained from patients in Canadian hospitals (CANWARD 2009 study). Antimicrobial Agents and Chemotherapy. 55: 2992-4. PMID 21422208 DOI: 10.1128/Aac.01696-10 |
0.548 |
|
| 2011 |
Karlowsky JA, Adam HJ, Decorby MR, Lagacé-Wiens PR, Hoban DJ, Zhanel GG. In vitro activity of ceftaroline against gram-positive and gram-negative pathogens isolated from patients in Canadian hospitals in 2009. Antimicrobial Agents and Chemotherapy. 55: 2837-46. PMID 21402844 DOI: 10.1128/Aac.01787-10 |
0.581 |
|
| 2011 |
Lagacé-Wiens PR, Tailor F, Simner P, DeCorby M, Karlowsky JA, Walkty A, Hoban DJ, Zhanel GG. Activity of NXL104 in combination with beta-lactams against genetically characterized Escherichia coli and Klebsiella pneumoniae isolates producing class A extended-spectrum beta-lactamases and class C beta-lactamases. Antimicrobial Agents and Chemotherapy. 55: 2434-7. PMID 21357295 DOI: 10.1128/Aac.01722-10 |
0.432 |
|
| 2011 |
Walkty A, Adam HJ, Laverdière M, Karlowsky JA, Hoban DJ, Zhanel GG. In vitro activity of ceftobiprole against frequently encountered aerobic and facultative Gram-positive and Gram-negative bacterial pathogens: results of the CANWARD 2007-2009 study. Diagnostic Microbiology and Infectious Disease. 69: 348-55. PMID 21353964 DOI: 10.1016/J.Diagmicrobio.2010.10.032 |
0.582 |
|
| 2011 |
Karlowsky JA, Adam HJ, Poutanen SM, Hoban DJ, Zhanel GG. In vitro activity of dalbavancin and telavancin against staphylococci and streptococci isolated from patients in Canadian hospitals: results of the CANWARD 2007-2009 study. Diagnostic Microbiology and Infectious Disease. 69: 342-7. PMID 21353963 DOI: 10.1016/J.Diagmicrobio.2010.10.031 |
0.598 |
|
| 2011 |
McCracken M, Mataseje LF, Loo V, Walkty A, Adam HJ, Hoban DJ, Zhanel GG, Mulvey MR. Characterization of Acinetobacter baumannii and meropenem-resistant Pseudomonas aeruginosa in Canada: results of the CANWARD 2007-2009 study. Diagnostic Microbiology and Infectious Disease. 69: 335-41. PMID 21353962 DOI: 10.1016/J.Diagmicrobio.2010.10.030 |
0.592 |
|
| 2011 |
Simner PJ, Zhanel GG, Pitout J, Tailor F, McCracken M, Mulvey MR, Lagacé-Wiens PR, Adam HJ, Hoban DJ. Prevalence and characterization of extended-spectrum β-lactamase- and AmpC β-lactamase-producing Escherichia coli: results of the CANWARD 2007-2009 study. Diagnostic Microbiology and Infectious Disease. 69: 326-34. PMID 21353961 DOI: 10.1016/J.Diagmicrobio.2010.10.029 |
0.487 |
|
| 2011 |
Nichol KA, Adam HJ, Hussain Z, Mulvey MR, McCracken M, Mataseje LF, Thompson K, Kost S, Lagacé-Wiens PR, Hoban DJ, Zhanel GG. Comparison of community-associated and health care-associated methicillin-resistant Staphylococcus aureus in Canada: results of the CANWARD 2007-2009 study. Diagnostic Microbiology and Infectious Disease. 69: 320-5. PMID 21353960 DOI: 10.1016/J.Diagmicrobio.2010.10.028 |
0.456 |
|
| 2011 |
Lagacé-Wiens PR, Simner PJ, Forward KR, Tailor F, Adam HJ, Decorby M, Karlowsky J, Hoban DJ, Zhanel GG. Analysis of 3789 in- and outpatient Escherichia coli isolates from across Canada--results of the CANWARD 2007-2009 study. Diagnostic Microbiology and Infectious Disease. 69: 314-9. PMID 21353959 DOI: 10.1016/J.Diagmicrobio.2010.10.027 |
0.584 |
|
| 2011 |
Adam HJ, DeCorby M, Rennie R, Karlowsky JA, Hoban DJ, Zhanel GG. Prevalence of antimicrobial resistant pathogens from blood cultures from Canadian hospitals: results of the CANWARD 2007-2009 study. Diagnostic Microbiology and Infectious Disease. 69: 307-13. PMID 21353958 DOI: 10.1016/J.Diagmicrobio.2010.10.026 |
0.569 |
|
| 2011 |
Zhanel GG, Adam HJ, Low DE, Blondeau J, Decorby M, Karlowsky JA, Weshnoweski B, Vashisht R, Wierzbowski A, Hoban DJ. Antimicrobial susceptibility of 15,644 pathogens from Canadian hospitals: results of the CANWARD 2007-2009 study. Diagnostic Microbiology and Infectious Disease. 69: 291-306. PMID 21353957 DOI: 10.1016/J.Diagmicrobio.2010.10.025 |
0.812 |
|
| 2011 |
Bera S, Zhanel GG, Schweizer F. Synthesis and antibacterial activity of amphiphilic lysine-ligated neomycin B conjugates. Carbohydrate Research. 346: 560-8. PMID 21353205 DOI: 10.1016/J.Carres.2011.01.015 |
0.304 |
|
| 2011 |
Zelenitsky SA, Ariano RE, Zhanel GG. Pharmacodynamics of empirical antibiotic monotherapies for an intensive care unit (ICU) population based on Canadian surveillance data. The Journal of Antimicrobial Chemotherapy. 66: 343-9. PMID 20926397 DOI: 10.1093/Jac/Dkq348 |
0.321 |
|
| 2011 |
Lagacé-Wiens PR, Nichol KA, Nicolle LE, Decorby MR, McCracken M, Alfa MJ, Mulvey MR, Zhanel GG. ESBL genotypes in fluoroquinolone-resistant and fluoroquinolone-susceptible ESBL-producing Escherichia coli urinary isolates in Manitoba. The Canadian Journal of Infectious Diseases & Medical Microbiology = Journal Canadien Des Maladies Infectieuses Et De La Microbiologie Medicale. 18: 133-7. PMID 18923714 DOI: 10.1155/2007/848194 |
0.539 |
|
| 2011 |
Zhanel GG, Hisanaga T, Wierzbowski A, Hoban DJ. Telithromycin in the treatment of acute bacterial sinusitis, acute exacerbations of chronic bronchitis, and community-acquired pneumonia. Therapeutics and Clinical Risk Management. 2: 59-75. PMID 18360582 |
0.747 |
|
| 2011 |
Zhanel G, Hammond G. Key research issues in Clostridium difficile. The Canadian Journal of Infectious Diseases & Medical Microbiology = Journal Canadien Des Maladies Infectieuses Et De La Microbiologie Medicale. 16: 282-5. PMID 18159559 DOI: 10.1155/2005/326367 |
0.367 |
|
| 2011 |
Noreddin AM, Elkhatib WF, Cunnion KM, Zhanel GG. Cumulative clinical experience from over a decade of use of levofoxacin in community-acquired pneumonia: Critical appraisal and role in therapy Drug, Healthcare and Patient Safety. 3: 59-68. |
0.308 |
|
| 2010 |
Manuel J, Zhanel GG, de Kievit T. Cadaverine suppresses persistence to carboxypenicillins in Pseudomonas aeruginosa PAO1. Antimicrobial Agents and Chemotherapy. 54: 5173-9. PMID 20855735 DOI: 10.1128/Aac.01751-09 |
0.364 |
|
| 2010 |
Zhanel GG, DeCorby M, Adam H, Mulvey MR, McCracken M, Lagacé-Wiens P, Nichol KA, Wierzbowski A, Baudry PJ, Tailor F, Karlowsky JA, Walkty A, Schweizer F, Johnson J, et al. Prevalence of antimicrobial-resistant pathogens in Canadian hospitals: results of the Canadian Ward Surveillance Study (CANWARD 2008). Antimicrobial Agents and Chemotherapy. 54: 4684-93. PMID 20805395 DOI: 10.1128/AAC.00469-10 |
0.82 |
|
| 2010 |
Findlay B, Zhanel GG, Schweizer F. Cationic amphiphiles, a new generation of antimicrobials inspired by the natural antimicrobial peptide scaffold. Antimicrobial Agents and Chemotherapy. 54: 4049-58. PMID 20696877 DOI: 10.1128/Aac.00530-10 |
0.484 |
|
| 2010 |
Lee JC, Greenwich JL, Zhanel GG, Han X, Cumming A, Saward L, McLoughlin RM. Modulation of the local neutrophil response by a novel hyaluronic acid-binding peptide reduces bacterial burden during staphylococcal wound infection. Infection and Immunity. 78: 4176-86. PMID 20643855 DOI: 10.1128/Iai.01364-09 |
0.46 |
|
| 2010 |
Zhanel GG, Calic D, Schweizer F, Zelenitsky S, Adam H, Lagacé-Wiens PR, Rubinstein E, Gin AS, Hoban DJ, Karlowsky JA. New lipoglycopeptides: a comparative review of dalbavancin, oritavancin and telavancin. Drugs. 70: 859-86. PMID 20426497 DOI: 10.2165/11534440-000000000-00000 |
0.518 |
|
| 2010 |
Bera S, Zhanel GG, Schweizer F. Evaluation of amphiphilic aminoglycoside-peptide triazole conjugates as antibacterial agents. Bioorganic & Medicinal Chemistry Letters. 20: 3031-5. PMID 20413307 DOI: 10.1016/J.Bmcl.2010.03.116 |
0.327 |
|
| 2010 |
Lynch JP, Zhanel GG. Streptococcus pneumoniae: epidemiology and risk factors, evolution of antimicrobial resistance, and impact of vaccines. Current Opinion in Pulmonary Medicine. 16: 217-25. PMID 20375783 DOI: 10.1097/Mcp.0B013E3283385653 |
0.514 |
|
| 2010 |
Bera S, Zhanel GG, Schweizer F. Antibacterial activities of aminoglycoside antibiotics-derived cationic amphiphiles. Polyol-modified neomycin B-, kanamycin A-, amikacin-, and neamine-based amphiphiles with potent broad spectrum antibacterial activity. Journal of Medicinal Chemistry. 53: 3626-31. PMID 20373816 DOI: 10.1021/Jm1000437 |
0.48 |
|
| 2010 |
Bera S, Zhanel GG, Schweizer F. Antibacterial activity of guanidinylated neomycin B- and kanamycin A-derived amphiphilic lipid conjugates. The Journal of Antimicrobial Chemotherapy. 65: 1224-7. PMID 20332193 DOI: 10.1093/Jac/Dkq083 |
0.531 |
|
| 2010 |
Zhanel GG, Harding GK, Rosser S, Hoban DJ, Karlowsky JA, Alfa M, Kabani A, Embil J, Gin A, Williams T, Nicolle LE. Low prevalence of VRE gastrointestinal colonization of hospitalized patients in Manitoba tertiary care and community hospitals. The Canadian Journal of Infectious Diseases = Journal Canadien Des Maladies Infectieuses. 11: 38-41. PMID 18159264 DOI: 10.1155/2000/356317 |
0.389 |
|
| 2009 |
Baudry PJ, Mataseje L, Zhanel GG, Hoban DJ, Mulvey MR. Characterization of plasmids encoding CMY-2 AmpC beta-lactamases from Escherichia coli in Canadian intensive care units. Diagnostic Microbiology and Infectious Disease. 65: 379-83. PMID 19775846 DOI: 10.1016/J.Diagmicrobio.2009.08.011 |
0.327 |
|
| 2009 |
Adam HJ, Laing NM, King CR, Lulashnyk B, Hoban DJ, Zhanel GG. In vitro activity of nemonoxacin, a novel nonfluorinated quinolone, against 2,440 clinical isolates. Antimicrobial Agents and Chemotherapy. 53: 4915-20. PMID 19738018 DOI: 10.1128/Aac.00078-09 |
0.598 |
|
| 2009 |
Walkty A, DeCorby M, Nichol K, Karlowsky JA, Hoban DJ, Zhanel GG. In vitro activity of colistin (polymyxin E) against 3,480 isolates of gram-negative bacilli obtained from patients in Canadian hospitals in the CANWARD study, 2007-2008 Antimicrobial Agents and Chemotherapy. 53: 4924-4926. PMID 19704135 DOI: 10.1128/Aac.00786-09 |
0.597 |
|
| 2009 |
Zhanel GG, Baudry PJ, Tailor F, Cox L, Hoban DJ, Karlowsky JA. Determination of the pharmacodynamic activity of clinically achievable tigecycline serum concentrations against clinical isolates of Escherichia coli with extended-spectrum beta-lactamases, AmpC beta-lactamases and reduced susceptibility to carbapenems using an in vitro model. The Journal of Antimicrobial Chemotherapy. 64: 824-8. PMID 19643776 DOI: 10.1093/Jac/Dkp254 |
0.37 |
|
| 2009 |
Mccracken M, Decorby M, Fuller J, Loo V, Hoban DJ, Zhanel GG, Mulvey MR. Identification of multidrug- and carbapenem-resistant Acinetobacter baumannii in Canada: Results from CANWARD 2007 Journal of Antimicrobial Chemotherapy. 64: 552-555. PMID 19578083 DOI: 10.1093/Jac/Dkp225 |
0.585 |
|
| 2009 |
Karlowsky JA, Lagacé-Wiens PR, Low DE, Zhanel GG. Annual macrolide prescription rates and the emergence of macrolide resistance among Streptococcus pneumoniae in Canada from 1995 to 2005. International Journal of Antimicrobial Agents. 34: 375-9. PMID 19560902 DOI: 10.1016/J.Ijantimicag.2009.05.008 |
0.526 |
|
| 2009 |
Karlowsky JA, Kaplan N, Hafkin B, Hoban DJ, Zhanel GG. AFN-1252, a FabI inhibitor, demonstrates a Staphylococcus-specific spectrum of activity. Antimicrobial Agents and Chemotherapy. 53: 3544-8. PMID 19487444 DOI: 10.1128/Aac.00400-09 |
0.569 |
|
| 2009 |
Zhanel GG, Voth D, Nichol K, Karlowsky JA, Noreddin AM, Hoban DJ. Pharmacodynamic activity of ceftobiprole compared with vancomycin versus methicillin-resistant Staphylococcus aureus (MRSA), vancomycin-intermediate Staphylococcus aureus (VISA) and vancomycin-resistant Staphylococcus aureus (VRSA) using an in vitro model. The Journal of Antimicrobial Chemotherapy. 64: 364-9. PMID 19454524 DOI: 10.1093/Jac/Dkp176 |
0.586 |
|
| 2009 |
Zhanel GG, Sniezek G, Schweizer F, Zelenitsky S, Lagacé-Wiens PR, Rubinstein E, Gin AS, Hoban DJ, Karlowsky JA. Ceftaroline: a novel broad-spectrum cephalosporin with activity against meticillin-resistant Staphylococcus aureus. Drugs. 69: 809-31. PMID 19441869 DOI: 10.2165/00003495-200969070-00003 |
0.526 |
|
| 2009 |
Johnson JR, Menard M, Johnston B, Kuskowski MA, Nichol K, Zhanel GG. Epidemic clonal groups of Escherichia coli as a cause of antimicrobial-resistant urinary tract infections in Canada, 2002 to 2004. Antimicrobial Agents and Chemotherapy. 53: 2733-9. PMID 19398649 DOI: 10.1128/Aac.00297-09 |
0.513 |
|
| 2009 |
Mataseje LF, Neumann N, Crago B, Baudry P, Zhanel GG, Louie M, Mulvey MR. Characterization of cefoxitin-resistant Escherichia coli isolates from recreational beaches and private drinking water in Canada between 2004 and 2006. Antimicrobial Agents and Chemotherapy. 53: 3126-30. PMID 19398647 DOI: 10.1128/Aac.01353-08 |
0.504 |
|
| 2009 |
Adam HJ, Hoban DJ, Gin AS, Zhanel GG. Association between fluoroquinolone usage and a dramatic rise in ciprofloxacin-resistant Streptococcus pneumoniae in Canada, 1997-2006. International Journal of Antimicrobial Agents. 34: 82-5. PMID 19342204 DOI: 10.1016/J.Ijantimicag.2009.02.002 |
0.537 |
|
| 2009 |
Lynch JP, Zhanel GG. Streptococcus pneumoniae: does antimicrobial resistance matter? Seminars in Respiratory and Critical Care Medicine. 30: 210-38. PMID 19296420 DOI: 10.1055/S-0029-1202939 |
0.594 |
|
| 2009 |
Baudry PJ, Nichol K, DeCorby M, Lagacé-Wiens P, Olivier E, Boyd D, Mulvey MR, Hoban DJ, Zhanel GG. Mechanisms of resistance and mobility among multidrug-resistant CTX-M-producing Escherichia coli from Canadian intensive care units: the 1st report of QepA in North America. Diagnostic Microbiology and Infectious Disease. 63: 319-26. PMID 19216943 DOI: 10.1016/J.Diagmicrobio.2008.12.001 |
0.522 |
|
| 2009 |
Wierzbowski AK, Karlowsky JA, Hoban DJ, Zhanel GG. In vitro activity of the investigational ketolide cethromycin against macrolide- and penicillin-resistant Streptococcus pneumoniae: review of the 1998 to 2006 Canadian Respiratory Organism Susceptibility Study (CROSS). The Journal of Antimicrobial Chemotherapy. 63: 620-2. PMID 19151038 DOI: 10.1093/Jac/Dkn532 |
0.784 |
|
| 2009 |
Zhanel GG, Karlowsky JA. In vitro activity of Iclaprim against respiratory and bacteremic isolates of Streptococcus pneumoniae. Antimicrobial Agents and Chemotherapy. 53: 1690-2. PMID 19139284 DOI: 10.1128/Aac.01388-08 |
0.561 |
|
| 2009 |
Noreddin AM, El-Khatib WF, Aolie J, Salem AH, Zhanel GG. Pharmacodynamic target attainment potential of azithromycin, clarithromycin, and telithromycin in serum and epithelial lining fluid of community-acquired pneumonia patients with penicillin-susceptible, intermediate, and resistant Streptococcus pneumoniae. International Journal of Infectious Diseases : Ijid : Official Publication of the International Society For Infectious Diseases. 13: 483-7. PMID 19046911 DOI: 10.1016/J.Ijid.2008.08.016 |
0.465 |
|
| 2009 |
Baudry PJ, McCracken M, Lagacé-Wiens P, Mulvey MR, Zhanel GG, Hoban DJ. Prevalence and Characterization of Extended-Spectrum Beta-Lactamase-Producing Enterobacteriaceae Isolated in Canadian Hospitals: Results from CANWARD 2007 Canadian Journal of Infectious Diseases and Medical Microbiology. 20: 43A-48A. DOI: 10.1155/2009/962617 |
0.472 |
|
| 2009 |
Nichol KA, McCracken M, DeCorby MR, Thompson K, Mulvey MR, Karlowsky JA, Hoban DJ, Zhanel GG. Comparison of Community-Associated and Health Care-Associated Methicillin-ResistantStaphylococcus aureusin Canada: Results from CANWARD 2007 Canadian Journal of Infectious Diseases and Medical Microbiology. 20: 31A-36A. DOI: 10.1155/2009/853676 |
0.455 |
|
| 2009 |
Zhanel GG, Vishisht V, Tam E, Hoban DJ, Karlowsky JA. Mutant Prevention Concentrations of Doripenem and Meropenem Alone and in Combination with Colistin (Polymyxin E), Levofloxacin and Tobramycin inPseudomonas aeruginosa Canadian Journal of Infectious Diseases and Medical Microbiology. 20: 67A-71A. DOI: 10.1155/2009/801612 |
0.539 |
|
| 2009 |
Lagacé-Wiens PR, DeCorby M, Baudry PJ, Hoban DJ, Karlowsky JA, Zhanel GG. Analysis of 1560 inpatient and outpatient Escherichia coli isolates from across Canada - Results from the CANWARD 2007 study Canadian Journal of Infectious Diseases & Medical Microbiology. 20. DOI: 10.1155/2009/784635 |
0.576 |
|
| 2009 |
Zhanel GG, DeCorby M, Nichol KA, Wierzbowski A, Baudry PJ, Tailor F, Lagacé-Wiens P, Walkty A, Fanella S, Larios O, Mulvey MR, McCracken M, Karlowsky JA, Hoban DJ. Antimicrobial susceptibility of 6685 organisms isolated from Canadian hospitals: CANWARD 2007. Canadian Journal of Infectious Diseases & Medical Microbiology. 20. DOI: 10.1155/2009/518471 |
0.774 |
|
| 2009 |
Walkty A, DeCorby M, Nichol K, McCracken M, Mulvey MR, Karlowsky JA, Hoban DJ, Zhanel GG. Characterization ofPseudomonas aeruginosaIsolates Obtained from Patients in Canadian Hospitals: Results of the CANWARD 2007 Study Canadian Journal of Infectious Diseases and Medical Microbiology. 20: 54A-58A. DOI: 10.1155/2009/431529 |
0.551 |
|
| 2009 |
Wierzbowski AK, Tailor F, Nichol K, Karlowsky JA, Hoban DJ, Zhanel GG. Antimicrobial-ResistantStreptococcus pneumoniaein Canadian Hospitals: Results from the 2007 CANWARD Study Canadian Journal of Infectious Diseases and Medical Microbiology. 20: 37A-42A. DOI: 10.1155/2009/286823 |
0.815 |
|
| 2009 |
Karlowsky JA, DeCorby M, Hoban DJ, Zhanel GG. In Vitro Activities of Ceftobiprole and Doripenem Tested against Frequently Encountered Aerobic and Facultative Gram-Positive and Gram-Negative Bacterial Pathogens Isolated from Patients in Canadian Hospitals in 2007 Canadian Journal of Infectious Diseases and Medical Microbiology. 20: 59A-66A. DOI: 10.1155/2009/183843 |
0.553 |
|
| 2009 |
Hoban D, Decorby M, Weshnoweski B, Vashisht R, Tailor F, Karlowsky J, Zhanel G. P93 Evaluation of the activity of ceftobiprole and doripenem against common clinical pathogens obtained from Canadian hospital wards using Etest methodology International Journal of Antimicrobial Agents. 34: S56. DOI: 10.1016/S0924-8579(09)70312-7 |
0.342 |
|
| 2009 |
Decorby M, Weshnoweski B, Vashisht R, Tailor F, Turner-Brannen E, McCracken M, Mulvey M, Karlowsky J, Lagace-Wiens P, Walkty A, Hoban D, Zhanel G. P67 Antimicrobial resistance in pathogens isolated from Canadian hospital clinics (C), emergency rooms (ER), medical/surgical wards (W) and intensive care units (ICU): results of the CANWARD 2008 study International Journal of Antimicrobial Agents. 34: S48. DOI: 10.1016/S0924-8579(09)70286-9 |
0.458 |
|
| 2009 |
Lagace-Wiens P, Baudry P, Decorby M, Zhanel G, Hoban D. P66 Escherichia coli isolates from Canadian hospitals – preliminary results of the CANWARD 2008 Study International Journal of Antimicrobial Agents. 34: S48. DOI: 10.1016/S0924-8579(09)70285-7 |
0.399 |
|
| 2009 |
Tailor F, Baudry P, Karlowsky J, Hoban D, Zhanel G. P60 Emergence of carbapenem reduced susceptible (CRS) E. coli (EC) and K. pneumoniae (KP) in Canadian hospitals: results from CANWARD 2007 and 2008 International Journal of Antimicrobial Agents. 34: S46. DOI: 10.1016/S0924-8579(09)70279-1 |
0.338 |
|
| 2009 |
Baudry P, Lagace-Wiens P, Zhanel G, Hoban D. P57 Extended-spectrum p-lactamase-producing Escherichia coli (ESBL-EC) from patients in Canadian hospitals: preliminary results from CANWARD 2008 International Journal of Antimicrobial Agents. 34: S45. DOI: 10.1016/S0924-8579(09)70276-6 |
0.342 |
|
| 2009 |
Wierzbowski A, Karlowsky J, Hoban D, Zhanel G. P49 Streptococcus pneumoniae in Canadian hospitals: demographics, prevalence and antibiotic susceptibility testing results obtained during 2007 and 2008 Canadian Ward Surveillance Study (CANWARD) International Journal of Antimicrobial Agents. 34: S42. DOI: 10.1016/S0924-8579(09)70268-7 |
0.751 |
|
| 2009 |
Zhanel G, Voth D, Karlowsky J, Decorby M, Noreddin A, Hoban D. P2 Pharmacodynamic (PD) activity of ceftobiprole (Cefto) compared to vancomycin (Vanco) vs. methicillin-resistant Staphylococcus aureus, vancomycin intermediate Staphylococcus aureus and vancomycin resistant Staphylococcus aureus using an in vitro model International Journal of Antimicrobial Agents. 34: S27-S28. DOI: 10.1016/S0924-8579(09)70221-3 |
0.552 |
|
| 2008 |
Lagacé-Wiens PR, Decorby MR, Baudry PJ, Hoban DJ, Karlowsky JA, Zhanel GG. Differences in antimicrobial susceptibility in Escherichia coli from Canadian intensive care units based on regional and demographic variables. The Canadian Journal of Infectious Diseases & Medical Microbiology = Journal Canadien Des Maladies Infectieuses Et De La Microbiologie MéDicale / Ammi Canada. 19: 282-6. PMID 19436508 DOI: 10.1155/2008/568458 |
0.489 |
|
| 2008 |
Zhanel GG, Decorby M, Nichol KA, Baudry PJ, Karlowsky JA, Lagace-Wiens PR, McCracken M, Mulvey MR, Hoban DJ. Characterization of methicillin-resistant Staphylococcus aureus, vancomycin-resistant enterococci and extended-spectrum beta-lactamase-producing Escherichia coli in intensive care units in Canada: Results of the Canadian National Intensive Care Unit (CAN-ICU) study (2005-2006). The Canadian Journal of Infectious Diseases & Medical Microbiology = Journal Canadien Des Maladies Infectieuses Et De La Microbiologie MéDicale / Ammi Canada. 19: 243-9. PMID 19412382 DOI: 10.1155/2008/714846 |
0.542 |
|
| 2008 |
Rotstein C, Evans G, Born A, Grossman R, Light RB, Magder S, McTaggart B, Weiss K, Zhanel GG. Clinical practice guidelines for hospital-acquired pneumonia and ventilator-associated pneumonia in adults. The Canadian Journal of Infectious Diseases & Medical Microbiology = Journal Canadien Des Maladies Infectieuses Et De La Microbiologie MéDicale / Ammi Canada. 19: 19-53. PMID 19145262 DOI: 10.1155/2008/593289 |
0.368 |
|
| 2008 |
Bera S, Zhanel GG, Schweizer F. Design, synthesis, and antibacterial activities of neomycin-lipid conjugates: polycationic lipids with potent gram-positive activity. Journal of Medicinal Chemistry. 51: 6160-4. PMID 18778047 DOI: 10.1021/Jm800345U |
0.478 |
|
| 2008 |
Karlowsky JA, Laing NM, Zhanel GG. In vitro activity of OPT-80 tested against clinical isolates of toxin-producing Clostridium difficile Antimicrobial Agents and Chemotherapy. 52: 4163-4165. PMID 18725442 DOI: 10.1128/Aac.00476-08 |
0.486 |
|
| 2008 |
Zhanel GG, Lam A, Schweizer F, Thomson K, Walkty A, Rubinstein E, Gin AS, Hoban DJ, Noreddin AM, Karlowsky JA. Ceftobiprole: a review of a broad-spectrum and anti-MRSA cephalosporin. American Journal of Clinical Dermatology. 9: 245-54. PMID 18572975 DOI: 10.2165/00128071-200809040-00004 |
0.533 |
|
| 2008 |
Zhanel GG, DeCorby M, Nichol KA, Wierzbowski A, Baudry PJ, Karlowsky JA, Lagacé-Wiens P, Walkty A, Mulvey MR, Hoban DJ. Antimicrobial susceptibility of 3931 organisms isolated from intensive care units in Canada: Canadian National Intensive Care Unit Study, 2005/2006. Diagnostic Microbiology and Infectious Disease. 62: 67-80. PMID 18513913 DOI: 10.1016/J.Diagmicrobio.2008.04.012 |
0.796 |
|
| 2008 |
Gawande PV, Lovetri K, Yakandawala N, Romeo T, Zhanel GG, Cvitkovitch DG, Madhyastha S. Antibiofilm activity of sodium bicarbonate, sodium metaperiodate and SDS combination against dental unit waterline-associated bacteria and yeast Journal of Applied Microbiology. 105: 986-992. PMID 18422552 DOI: 10.1111/J.1365-2672.2008.03823.X |
0.391 |
|
| 2008 |
Walkty A, Decorby M, Nichol K, Karlowsky JA, Hoban DJ, Zhanel GG. In vitro activity of ceftobiprole against clinical isolates of Pseudomonas aeruginosa obtained from Canadian intensive care unit (ICU) patients as part of the CAN-ICU Study Journal of Antimicrobial Chemotherapy. 62: 206-208. PMID 18385143 DOI: 10.1093/Jac/Dkn140 |
0.523 |
|
| 2008 |
Walkty A, Decorby M, Nichol K, Mulvey MR, Hoban D, Zhanel G. Antimicrobial susceptibility of Pseudomonas aeruginosa isolates obtained from patients in Canadian intensive care units as part of the Canadian National Intensive Care Unit study. Diagnostic Microbiology and Infectious Disease. 61: 217-21. PMID 18304774 DOI: 10.1016/J.Diagmicrobio.2008.01.009 |
0.528 |
|
| 2008 |
Baudry PJ, Nichol K, DeCorby M, Mataseje L, Mulvey MR, Hoban DJ, Zhanel GG. Comparison of antimicrobial resistance profiles among extended-spectrum-beta-lactamase-producing and acquired AmpC beta-lactamase-producing Escherichia coli isolates from Canadian intensive care units. Antimicrobial Agents and Chemotherapy. 52: 1846-9. PMID 18299417 DOI: 10.1128/Aac.01176-07 |
0.509 |
|
| 2008 |
Zhanel GG, DeCorby M, Laing N, Weshnoweski B, Vashisht R, Tailor F, Nichol KA, Wierzbowski A, Baudry PJ, Karlowsky JA, Lagacé-Wiens P, Walkty A, McCracken M, Mulvey MR, Johnson J, et al. Antimicrobial-resistant pathogens in intensive care units in Canada: results of the Canadian National Intensive Care Unit (CAN-ICU) study, 2005-2006. Antimicrobial Agents and Chemotherapy. 52: 1430-7. PMID 18285482 DOI: 10.1128/Aac.01538-07 |
0.824 |
|
| 2008 |
Zhanel GG, Trapp S, Gin AS, DeCorby M, Lagacé-Wiens PR, Rubinstein E, Hoban DJ, Karlowsky JA. Dalbavancin and telavancin: novel lipoglycopeptides for the treatment of Gram-positive infections. Expert Review of Anti-Infective Therapy. 6: 67-81. PMID 18251665 DOI: 10.1586/14787210.6.1.67 |
0.546 |
|
| 2008 |
Zhanel GG, Baudry P, Vashisht V, Laing N, Noreddin AM, Hoban DJ. Pharmacodynamic activity of ertapenem versus multidrug-resistant genotypically characterized extended-spectrum β-lactamase-producing Escherichia coli using an in vitro model Journal of Antimicrobial Chemotherapy. 61: 643-646. PMID 18238885 DOI: 10.1093/Jac/Dkm533 |
0.458 |
|
| 2008 |
Nichol KA, Adam HJ, Karlowsky JA, Zhanel GG, Hoban DJ. Increasing genetic relatedness of ciprofloxacin-resistant Streptococcus pneumoniae isolated in Canada from 1997 to 2005 Antimicrobial Agents and Chemotherapy. 52: 1190-1194. PMID 18180349 DOI: 10.1128/Aac.01260-07 |
0.443 |
|
| 2007 |
Noreddin AM, Reese AA, Ostroski M, Hoban DJ, Zhanel GG. Comparative pharmacodynamics of garenoxacin, gemifloxacin, and moxifloxacin in community-acquired pneumonia caused by Streptococcus pneumoniae: A Monte Carlo simulation analysis Clinical Therapeutics. 29: 2685-2689. PMID 18201584 DOI: 10.1016/J.Clinthera.2007.12.019 |
0.384 |
|
| 2007 |
Wierzbowski AK, Nichol K, Laing N, Hisanaga T, Nikulin A, Karlowsky JA, Hoban DJ, Zhanel GG. Macrolide resistance mechanisms among Streptococcus pneumoniae isolated over 6 years of Canadian Respiratory Organism Susceptibility Study (CROSS) (1998 2004). The Journal of Antimicrobial Chemotherapy. 60: 733-40. PMID 17673477 DOI: 10.1093/Jac/Dkm273 |
0.797 |
|
| 2007 |
Gin A, Dilay L, Karlowsky JA, Walkty A, Rubinstein E, Zhanel GG. Piperacillin-tazobactam: a beta-lactam/beta-lactamase inhibitor combination. Expert Review of Anti-Infective Therapy. 5: 365-83. PMID 17547502 DOI: 10.1586/14787210.5.3.365 |
0.373 |
|
| 2007 |
Zhanel GG, Wiebe R, Dilay L, Thomson K, Rubinstein E, Hoban DJ, Noreddin AM, Karlowsky JA. Comparative review of the carbapenems. Drugs. 67: 1027-52. PMID 17488146 DOI: 10.2165/00003495-200767070-00006 |
0.469 |
|
| 2007 |
Schurek KN, Wiebe R, Karlowsky JA, Rubinstein E, Hoban DJ, Zhanel GG. Faropenem: review of a new oral penem. Expert Review of Anti-Infective Therapy. 5: 185-98. PMID 17402834 DOI: 10.1586/14787210.5.2.185 |
0.452 |
|
| 2007 |
Karlowsky JA, Kasloff S, Nichol KA, Hoban DJ, Zhanel GG. Genetic relatedness of multidrug-resistant Escherichia coli cultured from geographically diverse outpatient, midstream urine specimens Diagnostic Microbiology and Infectious Disease. 58: 283-287. PMID 17376632 DOI: 10.1016/J.Diagmicrobio.2007.01.012 |
0.53 |
|
| 2007 |
Kays MB, Zhanel GG, Reimann MA, Jacobi J, Denys GA, Smith DW, Wack MF. Selection of a gyrA mutation and treatment failure with gatifloxacin in a patient with Streptococcus pneumoniae with a preexisting parC mutation. Pharmacotherapy. 27: 221-6. PMID 17253913 DOI: 10.1592/Phco.27.2.221 |
0.431 |
|
| 2007 |
Karlowsky JA, Laing NM, Baudry T, Kaplan N, Vaughan D, Hoban DJ, Zhanel GG. In vitro activity of API-1252, a novel FabI inhibitor, against clinical isolates of Staphylococcus aureus and Staphylococcus epidermidis. Antimicrobial Agents and Chemotherapy. 51: 1580-1. PMID 17220418 DOI: 10.1128/Aac.01254-06 |
0.474 |
|
| 2007 |
Bradley JS, Guidos R, Baragona S, Bartlett JG, Rubinstein E, Zhanel GG, Tino MD, Pompliano DL, Tally F, Tipirneni P, Tillotson GS, Powers JH, Tillotson GS. Anti-infective research and development--problems, challenges, and solutions. The Lancet. Infectious Diseases. 7: 68-78. PMID 17182346 DOI: 10.1016/S1473-3099(06)70689-2 |
0.356 |
|
| 2007 |
Zhanel GG, Derkatch S, Laing N, Noreddin AM, Hoban DJ. Pharmacodynamic activity of ertapenem versus penicillin-susceptible and penicillin-non-susceptible Streptococcus pneumoniae using an in vitro model Journal of Antimicrobial Chemotherapy. 59: 144-147. PMID 17079238 DOI: 10.1093/Jac/Dkl433 |
0.442 |
|
| 2007 |
Perdreau-Remington F, Zhanel G, Vaughan D, Kaplan N. P2090 In vitro activity of API-1252, a novel antistaphylococcal agent, against 100 genotypically unique Staphylococcus aureus strains International Journal of Antimicrobial Agents. 29: S604. DOI: 10.1016/S0924-8579(07)71929-5 |
0.383 |
|
| 2006 |
Hoban DJ, Zhanel GG. Clinical implications of macrolide resistance in community-acquired respiratory tract infections Expert Review of Anti-Infective Therapy. 4: 973-980. PMID 17181414 DOI: 10.1586/14787210.4.6.973 |
0.551 |
|
| 2006 |
Zhanel GG, Fontaine S, Adam H, Schurek K, Mayer M, Noreddin AM, Gin AS, Rubinstein E, Hoban DJ. A Review of New Fluoroquinolones : Focus on their Use in Respiratory Tract Infections. Treatments in Respiratory Medicine. 5: 437-65. PMID 17154673 DOI: 10.2165/00151829-200605060-00009 |
0.541 |
|
| 2006 |
Lynch JP, File TM, Zhanel GG. Levofloxacin for the treatment of community-acquired pneumonia Expert Review of Anti-Infective Therapy. 4: 725-742. PMID 17140350 DOI: 10.1586/14787210.4.5.725 |
0.445 |
|
| 2006 |
Adam HJ, Schurek KN, Nichol KA, Hoban CJ, Baudry TJ, Laing NM, Hoban DJ, Zhanel GG. Molecular characterization of increasing fluoroquinolone resistance in Streptococcus pneumoniae isolates in Canada, 1997 to 2005. Antimicrobial Agents and Chemotherapy. 51: 198-207. PMID 17088485 DOI: 10.1128/Aac.00609-06 |
0.55 |
|
| 2006 |
Zhanel GG, Wang X, Nichol K, Nikulin A, Wierzbowski AK, Mulvey M, Hoban DJ. Molecular characterisation of Canadian paediatric multidrug-resistant Streptococcus pneumoniae from 1998-2004. International Journal of Antimicrobial Agents. 28: 465-71. PMID 17049211 DOI: 10.1016/J.Ijantimicag.2006.08.005 |
0.801 |
|
| 2006 |
Schurek KN, Adam HJ, Hoban DJ, Zhanel GG. Call for the international adoption of microbiological breakpoints for fluoroquinolones and Streptococcus pneumoniae International Journal of Antimicrobial Agents. 28: 266-269. PMID 16904294 DOI: 10.1016/J.Ijantimicag.2006.04.007 |
0.508 |
|
| 2006 |
Nicolle L, Anderson PA, Conly J, Mainprize TC, Meuser J, Nickel JC, Senikas VM, Zhanel GG. Uncomplicated urinary tract infection in women. Current practice and the effect of antibiotic resistance on empiric treatment. Canadian Family Physician MéDecin De Famille Canadien. 52: 612-8. PMID 16739835 |
0.325 |
|
| 2006 |
Karlowsky JA, Hoban DJ, DeCorby MR, Laing NM, Zhanel GG. Fluoroquinolone-resistant urinary isolates of Escherichia coli from outpatients are frequently multidrug resistant: Results from the North American Urinary Tract Infection Collaborative Alliance-Quinolone Resistance Study Antimicrobial Agents and Chemotherapy. 50: 2251-2254. PMID 16723598 DOI: 10.1128/Aac.00123-06 |
0.578 |
|
| 2006 |
Zhanel GG, Mayer M, Laing N, Adam HJ. Mutant prevention concentrations of levofloxacin alone and in combination with azithromycin, ceftazidime, colistin (polymyxin E), meropenem, piperacillin-tazobactam, and tobramycin against Pseudomonas aeruginosa Antimicrobial Agents and Chemotherapy. 50: 2228-2230. PMID 16723591 DOI: 10.1128/Aac.01620-05 |
0.448 |
|
| 2006 |
Zhanel GG, Hisanaga TL, Laing NM, DeCorby MR, Nichol KA, Weshnoweski B, Johnson J, Noreddin A, Low DE, Karlowsky JA, Hoban DJ. Antibiotic resistance in Escherichia coli outpatient urinary isolates: final results from the North American Urinary Tract Infection Collaborative Alliance (NAUTICA). International Journal of Antimicrobial Agents. 27: 468-75. PMID 16713191 DOI: 10.1016/J.Ijantimicag.2006.02.009 |
0.606 |
|
| 2006 |
Zhanel GG, James J, Derkatch S, Laing N, Noreddin AM, Hoban DJ. Pharmacodynamic activity of garenoxacin against ciprofloxacin-resistant Streptococcus pneumoniae Journal of Antimicrobial Chemotherapy. 58: 112-116. PMID 16644764 DOI: 10.1093/Jac/Dkl159 |
0.51 |
|
| 2006 |
Burton E, Gawande PV, Yakandawala N, LoVetri K, Zhanel GG, Romeo T, Friesen AD, Madhyastha S. Antibiofilm activity of GlmU enzyme inhibitors against catheter-associated uropathogens. Antimicrobial Agents and Chemotherapy. 50: 1835-40. PMID 16641457 DOI: 10.1128/Aac.50.5.1835-1840.2006 |
0.417 |
|
| 2006 |
Adam HJ, Schurek KN, Decorby MR, Weshnoweski B, Vashisht R, Karlowsky K, Hoban DJ, Zhanel GG. Comparative in vitro activity of PGE 9262932 and fluoroquinolones against Canadian clinical Streptococcus pneumoniae isolates, including molecularly characterized ciprofloxacin-resistant isolates. The Journal of Antimicrobial Chemotherapy. 58: 202-4. PMID 16636082 DOI: 10.1093/Jac/Dkl152 |
0.587 |
|
| 2006 |
Nichol KA, Sill M, Laing NM, Johnson JL, Hoban DJ, Zhanel GG. Molecular epidemiology of urinary tract isolates of vancomycin-resistant Enterococcus faecium from North America. International Journal of Antimicrobial Agents. 27: 392-6. PMID 16621463 DOI: 10.1016/J.Ijantimicag.2005.12.006 |
0.576 |
|
| 2006 |
Wierzbowski AK, Hoban DJ, Hisanaga T, DeCorby M, Zhanel GG. The use of macrolides in treatment of upper respiratory tract infections. Current Allergy and Asthma Reports. 6: 171-81. PMID 16566868 DOI: 10.1007/S11882-006-0056-X |
0.791 |
|
| 2006 |
Lagacé-Wiens PR, Nichol KA, Nicolle LE, DeCorby M, McCracken M, Mulvey MR, Zhanel GG. Treatment of lower urinary tract infection caused by multidrug-resistant extended-spectrum-beta-lactamase-producing Escherichia coli with amoxicillin/clavulanate: case report and characterization of the isolate. The Journal of Antimicrobial Chemotherapy. 57: 1262-3. PMID 16565157 DOI: 10.1093/Jac/Dkl102 |
0.373 |
|
| 2006 |
ZhaneL GG, Karlowsky JA, Rubinstein E, Hoban D. Tigecycline: A novel glycylcycline antibiotic Expert Review of Anti-Infective Therapy. 4: 9-25. PMID 16441206 DOI: 10.1586/14787210.4.1.9 |
0.552 |
|
| 2006 |
Karlowsky JA, Hoban DJ, Zhanel GG, Goldstein BP. In vitro interactions of anidulafungin with azole antifungals, amphotericin B and 5-fluorocytosine against Candida species International Journal of Antimicrobial Agents. 27: 174-177. PMID 16414247 DOI: 10.1016/J.Ijantimicag.2005.10.014 |
0.403 |
|
| 2006 |
Nicolle LE, Zhanel GG, Harding GKM. Microbiological outcomes in women with diabetes and untreated asymptomatic bacteriuria World Journal of Urology. 24: 61-65. PMID 16389540 DOI: 10.1007/S00345-005-0042-2 |
0.331 |
|
| 2006 |
Zhanel GG, Hisanaga TL, Laing NM, DeCorby MR, Nichol KA, Palatnik LP, Johnson J, Noreddin A, Harding GK, Nicolle LE, Hoban DJ. Antibiotic resistance in outpatient urinary isolates: final results from the North American Urinary Tract Infection Collaborative Alliance (NAUTICA). International Journal of Antimicrobial Agents. 26: 380-8. PMID 16243229 DOI: 10.1016/J.Ijantimicag.2005.08.003 |
0.616 |
|
| 2006 |
Zhanel GG, Hisanaga T, Wierzbowski A, Hoban DJ. Telithromycin in the treatment of acute bacterial sinusitis, acute exacerbations of chronic bronchitis, and community-acquired pneumonia Therapeutics and Clinical Risk Management. 2: 59-75. |
0.345 |
|
| 2005 |
Lynch JP, Zhanel GG. Escalation of antimicrobial resistance among Streptococcus pneumoniae: Implications for therapy Seminars in Respiratory and Critical Care Medicine. 26: 575-616. PMID 16388429 DOI: 10.1055/S-2005-925524 |
0.595 |
|
| 2005 |
Wierzbowski AK, Boyd D, Mulvey M, Hoban DJ, Zhanel GG. Expression of the mef(E) gene encoding the macrolide efflux pump protein increases in Streptococcus pneumoniae with increasing resistance to macrolides. Antimicrobial Agents and Chemotherapy. 49: 4635-40. PMID 16251306 DOI: 10.1128/Aac.49.11.4635-4640.2005 |
0.779 |
|
| 2005 |
Schurek KN, Adam HJ, Siemens CG, Hoban CJ, Hoban DJ, Zhanel GG. Are fluoroquinolone-susceptible isolates of Streptococcus pneumoniae really susceptible? A comparison of resistance mechanisms in Canadian isolates from 1997 and 2003. The Journal of Antimicrobial Chemotherapy. 56: 769-72. PMID 16126779 DOI: 10.1093/Jac/Dki315 |
0.547 |
|
| 2005 |
Hisanaga T, Hoban DJ, Zhanel GG. Mechanisms of resistance to telithromycin in Streptococcus pneumoniae Journal of Antimicrobial Chemotherapy. 56: 447-450. PMID 16006449 DOI: 10.1093/Jac/Dki249 |
0.509 |
|
| 2005 |
Zhanel GG, Johanson C, Laing N, Hisanaga T, Wierzbowski A, Hoban DJ. Pharmacodynamic activity of telithromycin at simulated clinically achievable free-drug concentrations in serum and epithelial lining fluid against efflux (mefE)-producing macrolide-resistant Streptococcus pneumoniae for which telithromycin MICs vary Antimicrobial Agents and Chemotherapy. 49: 1943-1948. PMID 15855517 DOI: 10.1128/Aac.49.5.1943-1948.2005 |
0.751 |
|
| 2005 |
Wierzbowski AK, Hoban DJ, Hisanaga T, Decorby M, Zhanel GG. The Use of Macrolides in Treatment of Upper Respiratory Tract Infections. Current Infectious Disease Reports. 7: 175-184. PMID 15847719 DOI: 10.1007/S11908-005-0031-Z |
0.792 |
|
| 2005 |
Zhanel GG. Antibacterial drivers of resistance Treatments in Respiratory Medicine. 4: 13-18. PMID 15846152 DOI: 10.2165/00151829-200504001-00005 |
0.564 |
|
| 2005 |
Zhanel GG, Johanson C, Embil JM, Noreddin A, Gin A, Vercaigne L, Hoban DJ. Ertapenem: Review of a new carbapenem Expert Review of Anti-Infective Therapy. 3: 23-39. PMID 15757455 DOI: 10.1586/14787210.3.1.23 |
0.45 |
|
| 2005 |
Wierzbowski AK, Swedlo D, Boyd D, Mulvey M, Nichol KA, Hoban DJ, Zhanel GG. Molecular epidemiology and prevalence of macrolide efflux genes mef(A) and mef(E) in Streptococcus pneumoniae obtained in Canada from 1997 to 2002. Antimicrobial Agents and Chemotherapy. 49: 1257-61. PMID 15728944 DOI: 10.1128/Aac.49.3.1257-1261.2005 |
0.787 |
|
| 2005 |
Smith-Adam HJ, Nichol KA, Hoban DJ, Zhanel GG. Stability of fluoroquinolone resistance in Streptococcus pneumoniae clinical isolates and laboratory-derived mutants Antimicrobial Agents and Chemotherapy. 49: 846-848. PMID 15673786 DOI: 10.1128/Aac.49.2.846-848.2005 |
0.548 |
|
| 2005 |
Noreddin AM, Haynes VL, Zhanel GG. Pharmacokinetics and pharmacodynamics of the new quinolones Journal of Pharmacy Practice. 18: 432-443. DOI: 10.1177/0897190005282397 |
0.417 |
|
| 2004 |
Zhanel GG, Hoban DJ, Schurek K, Karlowsky JA. Role of efflux mechanisms on fluoroquinolone resistance in Streptococcus pneumoniae and Pseudomonas aeruginosa International Journal of Antimicrobial Agents. 24: 529-535. PMID 15555873 DOI: 10.1016/J.Ijantimicag.2004.08.003 |
0.569 |
|
| 2004 |
Zhanel GG, Johanson C, Hisanaga T, Mendoza C, Laing N, Noreddin A, Wierzbowski A, Hoban DJ. Pharmacodynamic activity of telithromycin against macrolide-susceptible and macrolide-resistant Streptococcus pneumoniae simulating clinically achievable free serum and epithelial lining fluid concentrations. The Journal of Antimicrobial Chemotherapy. 54: 1072-7. PMID 15531596 DOI: 10.1093/Jac/Dkh475 |
0.786 |
|
| 2004 |
Noreddin AM, Marras TK, Sanders K, Chan CK, Hoban DJ, Zhanel GG. Pharmacodynamic target attainment analysis against Streptococcus pneumoniae using levofloxacin 500 mg, 750 mg and 1000 mg once daily in plasma (P) and epithelial lining fluid (ELF) of hospitalized patients with community acquired pneumonia (CAP). International Journal of Antimicrobial Agents. 24: 479-84. PMID 15519481 DOI: 10.1016/J.Ijantimicag.2004.06.010 |
0.31 |
|
| 2004 |
Smith HJ, Walters M, Hisanaga T, Zhanel GG, Hoban DJ. Mutant prevention concentrations for single-step fluoroquinolone-resistant mutants of wild-type, efflux-positive, or ParC or GyrA mutation-containing Streptococcus pneumoniae isolates Antimicrobial Agents and Chemotherapy. 48: 3954-3958. PMID 15388458 DOI: 10.1128/Aac.48.10.3954-3958.2004 |
0.436 |
|
| 2004 |
Carrie AG, Metge CJ, Collins DM, Harding GK, Zhanel GG. Predictors of receipt of a fluoroquinolone versus trimethoprim-sulfamethoxazole for treatment of acute pyelonephritis in women in Manitoba, Canada. Pharmacoepidemiology and Drug Safety. 13: 863-70. PMID 15386718 DOI: 10.1002/Pds.949 |
0.476 |
|
| 2004 |
Smith HJ, Noreddin AM, Siemens CG, Schurek KN, Greisman J, Hoban CJ, Hoban DJ, Zhanel GG. Designing fluoroquinolone breakpoints for Streptococcus pneumoniae by using genetics instead of pharmacokinetics-pharmacodynamics. Antimicrobial Agents and Chemotherapy. 48: 3630-5. PMID 15328145 DOI: 10.1128/Aac.48.9.3630-3635.2004 |
0.458 |
|
| 2004 |
Powis J, McGeer A, Green K, Vanderkooi O, Weiss K, Zhanel G, Mazzulli T, Kuhn M, Church D, Davidson R, Forward K, Hoban D, Simor A, Low DE. In vitro antimicrobial susceptibilities of Streptococcus pneumoniae clinical isolates obtained in Canada in 2002. Antimicrobial Agents and Chemotherapy. 48: 3305-11. PMID 15328089 DOI: 10.1128/Aac.48.9.3305-3311.2004 |
0.573 |
|
| 2004 |
Rzeszutek M, Wierzbowski A, Hoban DJ, Conly J, Bishai W, Zhanel GG. A review of clinical failures associated with macrolide-resistant Streptococcus pneumoniae International Journal of Antimicrobial Agents. 24: 95-104. PMID 15288306 DOI: 10.1016/J.Ijantimicag.2004.03.008 |
0.754 |
|
| 2004 |
Zhanel GG, Wierzbowski AK, Hisanaga P, Hoban DJ. The Use of Ketolides in Treatment of Upper Respiratory Tract Infections. Current Infectious Disease Reports. 6: 191-199. PMID 15142482 |
0.775 |
|
| 2004 |
Zhanel GG, Homenuik K, Nichol K, Noreddin A, Vercaigne L, Embil J, Gin A, Karlowsky JA, Hoban DJ. The glycylcyclines: a comparative review with the tetracyclines. Drugs. 64: 63-88. PMID 14723559 DOI: 10.2165/00003495-200464010-00005 |
0.57 |
|
| 2003 |
Zhanel GG, Hisanaga T, Nichol K, Wierzbowski A, Hoban DJ. Ketolides: An emerging treatment for macrolide-resistant respiratory infections, focusing on S. pneumoniae Expert Opinion On Emerging Drugs. 8: 297-321. PMID 14661991 DOI: 10.1517/14728214.8.2.297 |
0.809 |
|
| 2003 |
Zhanel GG, Noreddin AM. Fluoroquinolone AUIC break points and the link to bacterial killing rates: In vitro models Annals of Pharmacotherapy. 37: 1331-1334. PMID 12921519 DOI: 10.1345/Aph.1D095 |
0.581 |
|
| 2003 |
Zhanel GG, Laing NM, Nichol KA, Palatnick LP, Noreddin A, Hisanaga T, Johnson JL, Hoban DJ. Antibiotic activity against urinary tract infection (UTI) isolates of vancomycin-resistant enterococci (VRE): results from the 2002 North American Vancomycin Resistant Enterococci Susceptibility Study (NAVRESS). The Journal of Antimicrobial Chemotherapy. 52: 382-8. PMID 12888592 DOI: 10.1093/Jac/Dkg352 |
0.598 |
|
| 2003 |
Zhanel GG, DeCorby M, Noreddin A, Mendoza C, Cumming A, Nichol K, Wierzbowski A, Hoban DJ. Pharmacodynamic activity of azithromycin against macrolide-susceptible and -resistant Streptococcus pneumoniae simulating clinically achievable free serum, epithelial lining fluid and middle ear fluid concentrations. The Journal of Antimicrobial Chemotherapy. 52: 83-8. PMID 12775677 DOI: 10.1093/Jac/Dkg278 |
0.774 |
|
| 2003 |
Zhanel GG, Palatnick L, Nichol KA, Low DE, Hoban DJ. Antimicrobial resistance in Haemophilus influenzae and Moraxella catarrhalis respiratory tract isolates: Results of the Canadian Respiratory Organism Susceptibility Study, 1997 to 2002 Antimicrobial Agents and Chemotherapy. 47: 1875-1881. PMID 12760861 DOI: 10.1128/Aac.47.6.1875-1881.2003 |
0.494 |
|
| 2003 |
Zhanel GG, Palatnick L, Nichol KA, Bellyou T, Low DE, Hoban DJ. Antimicrobial resistance in respiratory tract Streptococcus pneumoniae isolates: Results of the Canadian Respiratory Organism Susceptibility Study, 1997 to 2002 Antimicrobial Agents and Chemotherapy. 47: 1867-1874. PMID 12760860 DOI: 10.1128/Aac.47.6.1867-1874.2003 |
0.604 |
|
| 2003 |
Hoban DJ, Bouchillon SK, Johnson JL, Zhanel GG, Butler DL, Saunders KA, Miller LA, Poupard JA, Baron EJ, Sherretta A, Thomson R, Low D, Hoban D, Church D, Kibsey P, et al. Comparative in vitro potency of amoxycillin-clavulanic acid and four oral agents against recent North American clinical isolates from a global surveillance study International Journal of Antimicrobial Agents. 21: 425-433. PMID 12727075 DOI: 10.1016/S0924-8579(03)00038-4 |
0.518 |
|
| 2003 |
Hoban DJ, Bouchillon SK, Johnson JL, Zhanel GG, Butler DL, Saunders KA, Miller LA, Poupard JA. Comparative in vitro surveillance of amoxicillin-clavulanic acid and four oral comparators against 21,232 clinical isolates from Europe European Journal of Clinical Microbiology and Infectious Diseases. 22: 261-267. PMID 12709842 DOI: 10.1007/s10096-002-0876-0 |
0.322 |
|
| 2003 |
Zhanel GG, Walkty A, Nichol K, Smith H, Noreddin A, Hoban DJ. Molecular characterization of fluoroquinolone resistant Streptococcus pneumoniae clinical isolates obtained from across Canada Diagnostic Microbiology and Infectious Disease. 45: 63-67. PMID 12573552 DOI: 10.1016/S0732-8893(02)00498-4 |
0.575 |
|
| 2003 |
Nichol KA, Zhanel GG, Hoban DJ. Molecular epidemiology of penicillin-resistant and ciprofloxacin-resistant Streptococcus pneumoniae in Canada Antimicrobial Agents and Chemotherapy. 47: 804-808. PMID 12543698 DOI: 10.1128/Aac.47.2.804-808.2003 |
0.571 |
|
| 2003 |
Zhanel GG. In vitro activity of garenoxacin, a novel des-F(6)-fluoroquinolone Clinical Microbiology Newsletter. 25: 153-159. DOI: 10.1016/S0196-4399(03)80049-1 |
0.432 |
|
| 2002 |
Noreddin AM, Roberts D, Nichol K, Wierzbowski A, Hoban DJ, Zhanel GG. Pharmacodynamic modeling of clarithromycin against macrolide-resistant [PCR-positive mef(A) or erm(B)] Streptococcus pneumoniae simulating clinically achievable serum and epithelial lining fluid free-drug concentrations Antimicrobial Agents and Chemotherapy. 46: 4029-4034. PMID 12435719 DOI: 10.1128/Aac.46.12.4029-4034.2002 |
0.759 |
|
| 2002 |
Nichol KA, Zhanel GG, Hoban DJ. Penicillin-binding protein 1A, 2B, and 2X alterations in Canadian isolates of penicillin-resistant Streptococcus pneumoniae Antimicrobial Agents and Chemotherapy. 46: 3261-3264. PMID 12234855 DOI: 10.1128/Aac.46.10.3261-3264.2002 |
0.428 |
|
| 2002 |
Zhanel GG, Walters M, Noreddin A, Vercaigne LM, Wierzbowski A, Embil JM, Gin AS, Douthwaite S, Hoban DJ. The ketolides: a critical review. Drugs. 62: 1771-804. PMID 12149046 DOI: 10.2165/00003495-200262120-00006 |
0.788 |
|
| 2002 |
Zhanel GG, Hoban DJ, Chan CK. Resistance to levofloxacin and failure of treatment of pneumococcal pneumonia. The New England Journal of Medicine. 347: 65-7; author reply 6. PMID 12102063 |
0.352 |
|
| 2002 |
Zhanel GG, Roberts D, Waltky A, Laing N, Nichol K, Smith H, Noreddin A, Bellyou T, Hoban DJ. Pharmacodynamic activity of fluoroquinolones against ciprofloxacin-resistant Streptococcus pneumoniae. The Journal of Antimicrobial Chemotherapy. 49: 807-12. PMID 12003975 DOI: 10.1093/Jac/Dkf022 |
0.527 |
|
| 2002 |
Low DE, De Azavedo J, Weiss K, Mazzulli T, Kuhn M, Church D, Forward K, Zhanel G, Simor A, Krajden S, Price R, Paradis JF, Bocci L, Savard M, Rudrick BF, et al. Antimicrobial resistance among clinical isolates of Streptococcus pneumoniae in Canada during 2000 Antimicrobial Agents and Chemotherapy. 46: 1295-1301. PMID 11959559 DOI: 10.1128/Aac.46.5.1295-1301.2002 |
0.569 |
|
| 2002 |
Embil JM, Zhanel GG, Plourde PJ, Hoban D. Scissors: A potential source of nosocomial infection Infection Control and Hospital Epidemiology. 23: 147-151. PMID 11918121 DOI: 10.1086/502026 |
0.426 |
|
| 2002 |
Zhanel GG, Hoban DJ. Ketolides in the treatment of respiratory infections Expert Opinion On Pharmacotherapy. 3: 277-297. PMID 11866679 DOI: 10.1517/14656566.3.3.277 |
0.401 |
|
| 2002 |
Zhanel GG, Ennis K, Vercaigne L, Walkty A, Gin AS, Embil J, Smith H, Hoban DJ. A critical review of the fluoroquinolones: focus on respiratory infections. Drugs. 62: 13-59. PMID 11790155 DOI: 10.2165/00003495-200262010-00002 |
0.468 |
|
| 2002 |
Hoban DJ, Bouchillon SK, Johnson JL, Zhanel GG, Butler DL, Miller LA, Poupard JA. Comparative in vitro potency of gemifloxacin and fluoroquinolones against recent European clinical isolates from a global surveillance study. European Journal of Clinical Microbiology & Infectious Diseases : Official Publication of the European Society of Clinical Microbiology. 20: 814-9. PMID 11783700 DOI: 10.1007/s100960100604 |
0.487 |
|
| 2001 |
Mazzulli T, Skulnick M, Small G, Marshall W, Hoban DJ, Zhanel GG, Finn S, Low DE. Susceptibility of community Gram-negative urinary tract isolates to mecillinam and other oral agents. The Canadian Journal of Infectious Diseases = Journal Canadien Des Maladies Infectieuses. 12: 289-92. PMID 18159352 DOI: 10.1155/2001/601743 |
0.415 |
|
| 2001 |
Zhanel GG, Noreddin AM. Pharmacokinetics and pharmacodynamics of the new fluoroquinolones: Focus on respiratory infections Current Opinion in Pharmacology. 1: 459-463. PMID 11764770 DOI: 10.1016/S1471-4892(01)00080-7 |
0.503 |
|
| 2001 |
Felmingham D, Zhanel G, Hoban D. Activity of the ketolide antibacterial telithromycin against typical community-acquired respiratory pathogens. The Journal of Antimicrobial Chemotherapy. 33-42. PMID 11566974 DOI: 10.1093/jac/48.suppl_2.33 |
0.306 |
|
| 2001 |
Hoban DJ, Bouchillon SK, Johnson JL, Zhanel GG, Butler DL, Miller LA, Poupard JA. Comparative in vitro activity of gemifloxacin, ciprofloxacin, levofloxacin and ofloxacin in a North American surveillance study. Diagnostic Microbiology and Infectious Disease. 40: 51-7. PMID 11448564 DOI: 10.1016/S0732-8893(01)00241-3 |
0.571 |
|
| 2001 |
Hoban DJ, Wierzbowski AK, Nichol K, Zhanel GG. Macrolide-resistant Streptococcus pneumoniae in Canada during 1998-1999: prevalence of mef(A) and erm(B) and susceptibilities to ketolides. Antimicrobial Agents and Chemotherapy. 45: 2147-50. PMID 11408241 DOI: 10.1128/Aac.45.7.2147-2150.2001 |
0.807 |
|
| 2001 |
Zhanel GG, Saunders DG, Hoban DJ, Karlowsky JA. Influence of human serum on antifungal pharmacodynamics with Candida albicans Antimicrobial Agents and Chemotherapy. 45: 2018-2022. PMID 11408217 DOI: 10.1128/Aac.45.7.2018-2022.2001 |
0.46 |
|
| 2001 |
Zhanel GG, Dueck M, Hoban DJ, Vercaigne LM, Embil JM, Gin AS, Karlowsky JA. Review of macrolides and ketolides: focus on respiratory tract infections. Drugs. 61: 443-98. PMID 11324679 DOI: 10.2165/00003495-200161040-00003 |
0.501 |
|
| 2001 |
Zhanel GG, Walters M, Laing N, Hoban DJ. In vitro pharmacodynamic modelling simulating free serum concentrations of fluoroquinolones against multidrug-resistant Streptococcus pneumoniae Journal of Antimicrobial Chemotherapy. 47: 435-440. PMID 11266416 DOI: 10.1093/Jac/47.4.435 |
0.567 |
|
| 2001 |
Zhanel GG, Hoban DJ, Karlowsky JA. Nitrofurantoin is active against vancomycin-resistant enterococci Antimicrobial Agents and Chemotherapy. 45: 324-326. PMID 11120989 DOI: 10.1128/Aac.45.1.324-326.2001 |
0.604 |
|
| 2001 |
Zhanel GG, Schroeder C, Vercaigne L, Gin AS, Embil J, Hoban DJ. A critical review of oxazolidinones: An alternative or replacement for glycopeptides and streptogramins? Canadian Journal of Infectious Diseases. 12: 379-390. |
0.501 |
|
| 2000 |
Karlowsky JA, Verma G, Zhanel GG, Hoban DJ. Presence of ROB-1 β-lactamase correlates with cefaclor resistance among recent isolates of Haemophilus influenzae Journal of Antimicrobial Chemotherapy. 45: 871-875. PMID 10837442 DOI: 10.1093/Jac/45.6.871 |
0.505 |
|
| 2000 |
Zhanel GG, Karlowsky JA, Low DE, Hoban DJ. Antibiotic resistance in respiratory tract isolates of Haemophilus influenzae and Moraxella catarrhalis collected from across Canada in 1997-1998 Journal of Antimicrobial Chemotherapy. 45: 655-662. PMID 10797089 DOI: 10.1093/Jac/45.5.655 |
0.496 |
|
| 2000 |
Carrie AG, Metge CJ, Zhanel GG. Antibiotic use in a Canadian province, 1995-1998 Annals of Pharmacotherapy. 34: 459-464. PMID 10772430 DOI: 10.1345/Aph.19131 |
0.429 |
|
| 2000 |
Zhanel GG, Karlowsky JA, Harding GK, Carrie A, Mazzulli T, Low DE, Hoban DJ. A Canadian national surveillance study of urinary tract isolates from outpatients: comparison of the activities of trimethoprim-sulfamethoxazole, ampicillin, mecillinam, nitrofurantoin, and ciprofloxacin. The Canadian Urinary Isolate Study Group. Antimicrobial Agents and Chemotherapy. 44: 1089-92. PMID 10722520 DOI: 10.1128/Aac.44.4.1089-1092.2000 |
0.559 |
|
| 2000 |
Vercaigne LM, Zhanel GG. Antibiotic-heparin lock: In vitro confirmation of antibacterial activity Canadian Journal of Hospital Pharmacy. 53: 193-198. DOI: 10.4212/Cjhp.V53I3.729 |
0.424 |
|
| 1999 |
Zhanel GG, Siemens S, Slayter K, Mandell L. Antibiotic and oral contraceptive drug interactions: Is there a need for concern? The Canadian Journal of Infectious Diseases = Journal Canadien Des Maladies Infectieuses. 10: 429-33. PMID 22346401 DOI: 10.1155/1999/539376 |
0.331 |
|
| 1999 |
Hoban DJ, Zhanel GG, Karlowsky JA. In vitro activity of the novel ketolide HMR 3647 and comparative oral antibiotics against Canadian respiratory tract isolates of Streptococcus pneumoniae, Haemophilus influenzae, and Moraxella catarrhalis Diagnostic Microbiology and Infectious Disease. 35: 37-44. PMID 10529880 DOI: 10.1016/S0732-8893(99)00053-X |
0.526 |
|
| 1999 |
Karlowsky JA, Zhanel GG, Hoban DJ. Vancomycin-resistant enterococci (VRE) colonization of high-risk patients in tertiary care Canadian hospitals Diagnostic Microbiology and Infectious Disease. 35: 1-7. PMID 10529874 DOI: 10.1016/S0732-8893(99)00045-0 |
0.549 |
|
| 1999 |
Zhanel GG, Karlowsky JA, Palatnick L, Vercaigne L, Low DE, Hoban DJ. Prevalence of antimicrobial resistance in respiratory tract isolates of Streptococcus pneumoniae: Results of a canadian national surveillance study Antimicrobial Agents and Chemotherapy. 43: 2504-2509. PMID 10508032 DOI: 10.1128/Aac.44.11.3247-3247.2000 |
0.544 |
|
| 1999 |
Carrie AG, Zhanel GG. Antibacterial use in community practice. Assessing quantity, indications and appropriateness, and relationship to the development of antibacterial resistance Drugs. 57: 871-881. PMID 10400402 DOI: 10.2165/00003495-199957060-00004 |
0.482 |
|
| 1999 |
Hoban DJ, Zhanel GG, Karlowsky JA. In vitro susceptibilities of Candida and Cryptococcus neoformans isolates from blood cultures of neutropenic patients Antimicrobial Agents and Chemotherapy. 43: 1463-1464. PMID 10348771 DOI: 10.1128/Aac.43.6.1463 |
0.537 |
|
| 1999 |
Zelenitsky SA, Booker B, Laing N, Karlowsky JA, Hoban DJ, Zhanel GG. Synergy of an investigational glycopeptide, LY333328, with once-daily gentamicin against vancomycin-resistant Enterococcus faecium in a multiple- dose, in vitro pharmacodynamic model Antimicrobial Agents and Chemotherapy. 43: 592-597. PMID 10049272 DOI: 10.1128/Aac.43.3.592 |
0.387 |
|
| 1999 |
Balko T, Karlowsky JA, Palatnick LP, Zhanel GG, Hoban DJ. Characterization of the inoculum effect with Haemophilus influenzae and β-lactams Diagnostic Microbiology and Infectious Disease. 33: 47-58. PMID 9990476 DOI: 10.1016/S0732-8893(98)00117-5 |
0.307 |
|
| 1999 |
Hoban D, Zhanel G, Palatnick L, Weshnoweski B, Vercaigne L, Karlowsky J. Grepafloxacin Activity Against 3000 Canadian Respiratory Tract Pathogens Drugs. 58: 358-360. DOI: 10.2165/00003495-199958002-00122 |
0.344 |
|
| 1998 |
Zhanel GG, Karlowsky JA, Schwartz B, Jensen SB, Hoban DJ. Mecillinam activity compared to ampicillin, trimethoprim/sulfamethoxazole, ciprofloxacin and nitrofurantoin against urinary tract isolates of gram-negative bacilli Chemotherapy. 44: 391-396. PMID 9755298 DOI: 10.1159/000007149 |
0.574 |
|
| 1998 |
Zhanel GG, Karlowsky JA, Zelenitsky SA, Turik MA, Hoban DJ. Susceptibilities of Candida species isolated from the lower gastrointestinal tracts of high-risk patients to the new semisynthetic echinocandin LY303366 and other antifungal agents Antimicrobial Agents and Chemotherapy. 42: 2446-2448. PMID 9736582 DOI: 10.1128/Aac.42.9.2446 |
0.381 |
|
| 1998 |
Zhanel GG, Kirkpatrick IDC, Hoban DJ, Kabani AM, Karlowsky JA. Influence of human serum on pharmacodynamic properties of an investigational glycopeptide, LY333328, and comparator agents against Staphylococcus aureus Antimicrobial Agents and Chemotherapy. 42: 2427-2430. PMID 9736576 DOI: 10.1128/Aac.42.9.2427 |
0.462 |
|
| 1998 |
Turenne CY, Hoban DJ, Karlowsky JA, Zhanel GG, Kabani AM. Screening of stool samples for identification of vancomycin-resistant Enterococcus isolates should include the methyl-α-D-glucopyranoside test to differentiate nonmotile Enterococcus gallinarum from E. faecium Journal of Clinical Microbiology. 36: 2333-2335. PMID 9666016 DOI: 10.1128/Jcm.36.8.2333-2335.1998 |
0.417 |
|
| 1998 |
Zhanel GG, Karlowsky JA, Hoban DJ. In vitro activities of six fluoroquinolones against Canadian isolates of vancomycin-sensitive and vancomycin-resistant Enterococcus species Diagnostic Microbiology and Infectious Disease. 31: 343-347. PMID 9635908 DOI: 10.1016/S0732-8893(98)00019-4 |
0.546 |
|
| 1998 |
Zelenitsky SA, Karlowsky JA, Hoban DJ, Kabani A, Zhanel GG. Once versus thrice daily tobramycin alone and in combination with ceftazidime, ciprofloxacin and imipenem in an in vitro pharmacodynamic model Chemotherapy. 44: 1-6. PMID 9444401 DOI: 10.1159/000007083 |
0.364 |
|
| 1997 |
Karlowsky JA, Zhanel GG, Klym KA, Hoban DJ, Kabani AM. Candidemia in a Canadian tertiary care hospital from 1976 to 1996 Diagnostic Microbiology and Infectious Disease. 29: 5-9. PMID 9350409 DOI: 10.1016/S0732-8893(97)00068-0 |
0.349 |
|
| 1997 |
Karlowsky JA, Hoban DJ, Zelenitsky SA, Zhanel GG. Altered denA and anr gene expression in aminoglycoside adaptive resistance in Pseudomonas aeruginosa Journal of Antimicrobial Chemotherapy. 40: 371-376. PMID 9338489 DOI: 10.1093/Jac/40.3.371 |
0.484 |
|
| 1997 |
Karlowsky JA, Zhanel GG, Balko TV, Zelenitsky SA, Kabani AM, Hoban DJ. In vitro antifungal activity of BMS-181184 against systemic isolates of Candida, Cryptococcus, and Blastomyces species. Diagnostic Microbiology and Infectious Disease. 28: 179-82. PMID 9327245 DOI: 10.1016/S0732-8893(97)00061-8 |
0.443 |
|
| 1997 |
Zelenitsky SA, Karlowsky JA, Zhanel GG, Hoban DJ, Nicas T. Time-kill curves for a semisynthetic glycopeptide, LY333328, against vancomycin-susceptible and vancomycin-resistant Enterococcus faecium strains [2] Antimicrobial Agents and Chemotherapy. 41: 1407-1408. PMID 9174212 DOI: 10.1128/Aac.41.6.1407 |
0.493 |
|
| 1997 |
Karlowsky JA, Zelenitsky SA, Zhanel GG. Aminoglycoside adaptive resistance Pharmacotherapy. 17: 549-555. PMID 9165557 DOI: 10.1002/J.1875-9114.1997.Tb03063.X |
0.531 |
|
| 1997 |
Zhanel GG, Karlowsky JA, Harding GA, Balko TV, Zelenitsky SA, Friesen M, Kabani A, Turik M, Hoban DJ. In vitro activity of a new semisynthetic echinocandin, LY-303366, against systemic isolates of Candida species, Cryptococcus neoformans, Blastomyces dermatitidis, and Aspergillus species. Antimicrobial Agents and Chemotherapy. 41: 863-865. DOI: 10.1128/Aac.41.4.863 |
0.373 |
|
| 1997 |
Karlowsky JA, Harding GA, Zelenitsky SA, Hoban DJ, Kabani A, Balko TV, Turik M, Zhanel GG. In vitro kill curves of a new semisynthetic echinocandin, LY-303366, against fluconazole-sensitive and -resistant Candida species. Antimicrobial Agents and Chemotherapy. 41: 2576-2578. DOI: 10.1128/Aac.41.11.2576 |
0.431 |
|
| 1996 |
Rapp RP, Gin AS, Zhanel GG. Comment: Vancomycin-resistant enterococci [8] Annals of Pharmacotherapy. 30: 1500. PMID 9063961 |
0.444 |
|
| 1996 |
Gin AS, Zhanel GG. Vancomycin-resistant enterococci Annals of Pharmacotherapy. 30: 615-624. PMID 8792949 DOI: 10.1177/106002809603000610 |
0.521 |
|
| 1996 |
Drobot GR, Karlowsky JA, Hoban DJ, Zhanel GG. Antibiotic activity in microbiological media versus that in human urine: Comparison of ampicillin, ciprofloxacin, and trimethoprim-sulfamethoxazolc Antimicrobial Agents and Chemotherapy. 40: 237-240. PMID 8787914 DOI: 10.1128/Aac.40.1.237 |
0.442 |
|
| 1996 |
Karlowsky JA, Saunders MH, Harding GAJ, Hoban DJ, Zhanel GG. In vitro characterization of aminoglycoside adaptive resistance in Pseudomonas aeruginosa Antimicrobial Agents and Chemotherapy. 40: 1387-1393. PMID 8726006 DOI: 10.1128/Aac.40.6.1387 |
0.503 |
|
| 1995 |
Zhanel GG, Karlowsky JA, Saunders MH, Davidson RJ, Hoban DJ, Hancock RE, McLean I, Nicolle LE. Development of multiple-antibiotic-resistant (Mar) mutants of Pseudomonas aeruginosa after serial exposure to fluoroquinolones. Antimicrobial Agents and Chemotherapy. 39: 489-95. PMID 7726519 DOI: 10.1128/Aac.39.2.489 |
0.523 |
|
| 1995 |
Kroeker JS, Karlowsky JA, Zhanel GG. Recommendations for the calculation of the post-antibiotic effect for β-lactams and gram-negative bacilli Journal of Antimicrobial Chemotherapy. 35: 551-552. PMID 7628990 DOI: 10.1093/Jac/35.4.551 |
0.362 |
|
| 1994 |
Vercaigne LM, Zhanel GG. Recommended treatment for urinary tract infection in pregnancy Annals of Pharmacotherapy. 28: 248-251. PMID 8173146 DOI: 10.1177/106002809402800218 |
0.311 |
|
| 1994 |
Zhanel GG, Craig WA. Pharmacokinetic Contributions to Postantibiotic Effects: Focus on Aminoglycosides Clinical Pharmacokinetics. 27: 377-392. PMID 7851055 DOI: 10.2165/00003088-199427050-00005 |
0.448 |
|
| 1993 |
Karlowsky JA, Zhanel GG, Davidson RJ, Zieroth SR, Hoban DJ. In vitro postantibiotic effects following multiple exposures of cefotaxime, ciprofloxacin, and gentamicin against Escherichia coli in pooled human cerebrospinal fluid and Mueller-Hinton broth Antimicrobial Agents and Chemotherapy. 37: 1154-1157. PMID 8517705 DOI: 10.1128/Aac.37.5.1154 |
0.346 |
|
| 1993 |
Zhanel GG, Kim SO, Davidson RJ, Hoban DJ, Nicolle LE. Effect of subinhibitory concentrations of ciprofloxacin and gentamicin on the adherence of Pseudomonas aeruginosa to vero cells and voided uroepithelial cells Chemotherapy. 39: 105-111. PMID 8458242 DOI: 10.1159/000239110 |
0.394 |
|
| 1992 |
Zhanel GG, Karlowsky JA, Davidson RJ, Hoban DJ. Effect of pooled human cerebrospinal fluid on the postantibiotic effects of cefotaxime, ciprofloxacin, and gentamicin against Escherichia coli Antimicrobial Agents and Chemotherapy. 36: 1136-1139. PMID 1510407 DOI: 10.1128/Aac.36.5.1136 |
0.414 |
|
| 1992 |
Zhanel GG, Nicolle LE. Effect of subinhibitory antimicrobial concentrations (sub-MICs) on in-vitro bacterial adherence to uroepithelial cells Journal of Antimicrobial Chemotherapy. 29: 617-627. PMID 1506346 DOI: 10.1093/Jac/29.6.617 |
0.416 |
|
| 1992 |
Karlowsky JA, Zhanel GG. Concepts on the use of liposomal antimicrobial agents: Applications for aminoglycosides Clinical Infectious Diseases. 15: 654-667. PMID 1420679 DOI: 10.1093/Clind/15.4.654 |
0.366 |
|
| 1991 |
Ariano RE, Zhanel GG. Antimicrobial prophylaxis in coronary bypass surgery: A critical appraisal Dicp, Annals of Pharmacotherapy. 25: 478-484. PMID 2068834 DOI: 10.1177/106002809102500508 |
0.388 |
|
| 1991 |
Zhanel GG, Hoban DJ, Harding GKm. The postantibiotic effect: A review of in vitro and in vivo data Annals of Pharmacotherapy. 25: 153-163. PMID 2058187 DOI: 10.1177/106002809102500210 |
0.467 |
|
| 1991 |
Davidson RJ, Zhanel GG, Phillips R, Hoban DJ. Human serum enhances the postantibiotic effect of fluoroquinolones against Staphylococcus aureus Antimicrobial Agents and Chemotherapy. 35: 1261-1263. PMID 1929278 DOI: 10.1128/Aac.35.6.1261 |
0.36 |
|
| 1991 |
Zhanel GG, Karlowsky JA, Hoban DJ, Davidson RJ. Antimicrobial activity of subinhibitory concentrations of aminoglycosides against pseudomonas aeruginosa as determined by the killing-curve method and the postantibiotic effect Chemotherapy. 37: 114-121. PMID 1903340 DOI: 10.1159/000238842 |
0.324 |
|
| 1991 |
Zhanel GG, Karlowsky JA, Davidson RJ, Hoban DJ. Influence of human urine on the in vitro activity and postantibiotic effect of ciprofloxacin against Escherichia coli Chemotherapy. 37: 218-223. PMID 1889309 DOI: 10.1159/000238857 |
0.305 |
|
| 1990 |
Zhanel GG, Davidson RJ, Hoban DJ. Reproducibility of the in-vitro postantibiotic effect of fluoroquinolones against staphylococcus aureus Journal of Antimicrobial Chemotherapy. 26: 724-726. PMID 2079455 DOI: 10.1093/Jac/26.5.724 |
0.509 |
|
| 1988 |
Zhanel GG, Brunham RC. Third-generation cephalosporins Canadian Journal of Hospital Pharmacy. 41: 183-194. |
0.324 |
|
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