| Year |
Citation |
Score |
| 2023 |
Hewitt N, Ma N, Arang N, Martin SA, Prakash A, DiBerto JF, Knight KM, Ghosh S, Olsen RHJ, Roth BL, Gutkind JS, Vaidehi N, Campbell SL, Dohlman HG. Catalytic site mutations confer multiple states of G protein activation. Science Signaling. 16: eabq7842. PMID 36787384 DOI: 10.1126/scisignal.abq7842 |
0.629 |
|
| 2022 |
Li S, Li Y, Rushing BR, Harris SE, McRitchie SL, Dominguez D, Sumner SJ, Dohlman HG. Multi-Omics Analysis of Multiple Glucose-Sensing Receptor Systems in Yeast. Biomolecules. 12. PMID 35204676 DOI: 10.3390/biom12020175 |
0.358 |
|
| 2021 |
Li S, Li Y, Rushing BR, Harris SE, McRitchie SL, Jones JC, Dominguez D, Sumner SJ, Dohlman HG. Multi-omics analysis of glucose-mediated signaling by a moonlighting Gβ protein Asc1/RACK1. Plos Genetics. 17: e1009640. PMID 34214075 DOI: 10.1371/journal.pgen.1009640 |
0.766 |
|
| 2021 |
Suzuki SK, Kelley JB, Elston TC, Dohlman HG. Gradient Tracking by Yeast GPCRs in a Microfluidics Chamber. Methods in Molecular Biology (Clifton, N.J.). 2268: 275-287. PMID 34085275 DOI: 10.1007/978-1-0716-1221-7_18 |
0.612 |
|
| 2021 |
Knight KM, Ghosh S, Campbell SL, Lefevre TJ, Olsen RHJ, Smrcka AV, Valentin NH, Yin G, Vaidehi N, Dohlman HG. A universal allosteric mechanism for G protein activation. Molecular Cell. PMID 33636126 DOI: 10.1016/j.molcel.2021.02.002 |
0.641 |
|
| 2021 |
Pomeroy AE, Peña MI, Houser JR, Dixit G, Dohlman HG, Elston TC, Errede B. A predictive model of gene expression reveals the role of network motifs in the mating response of yeast. Science Signaling. 14. PMID 33593998 DOI: 10.1126/scisignal.abb5235 |
0.788 |
|
| 2020 |
Rangarajan N, Kapoor I, Li S, Drossopoulos P, White KK, Madden VJ, Dohlman HG. Potassium starvation induces autophagy in yeast. The Journal of Biological Chemistry. PMID 32788210 DOI: 10.1074/Jbc.Ra120.014687 |
0.348 |
|
| 2019 |
Dohlman HG, Campbell SL. Regulation of large and small G proteins by ubiquitination. The Journal of Biological Chemistry. PMID 31645437 DOI: 10.1074/Jbc.Rev119.011068 |
0.687 |
|
| 2019 |
Rangarajan N, Gordy CL, Askew L, Bevill SM, Elston TC, Errede B, Hurst JH, Kelley JB, Sheetz JB, Suzuki SK, Valentin NH, Young E, Dohlman HG. Systematic analysis of F-box proteins reveals a new branch of the yeast mating pathway. The Journal of Biological Chemistry. PMID 31399514 DOI: 10.1074/Jbc.Ra119.010063 |
0.845 |
|
| 2019 |
Shellhammer JP, Pomeroy AE, Li Y, Dujmusic L, Elston TC, Hao N, Dohlman HG. Quantitative analysis of the yeast pheromone pathway. Yeast (Chichester, England). PMID 31022772 DOI: 10.1002/Yea.3395 |
0.829 |
|
| 2017 |
Isom DG, Page SC, Collins LB, Kapolka NJ, Taghon GJ, Dohlman HG. Coordinated Regulation of Intracellular pH by Two Glucose Sensing Pathways in Yeast. The Journal of Biological Chemistry. PMID 29284676 DOI: 10.1074/Jbc.Ra117.000422 |
0.791 |
|
| 2017 |
Shellhammer JP, Morin-Kensicki E, Matson JP, Yin G, Isom DG, Campbell SL, Mohney RP, Dohlman HG. Amino acid metabolites that regulate G protein signaling during osmotic stress. Plos Genetics. 13: e1006829. PMID 28558063 DOI: 10.1371/Journal.Pgen.1006829 |
0.83 |
|
| 2016 |
Dohlman HG. Thematic Minireview Series: Complexities of cellular signaling revealed by simple model organisms. The Journal of Biological Chemistry. PMID 26907688 DOI: 10.1074/Jbc.R116.722934 |
0.41 |
|
| 2016 |
Isom DG, Sridharan V, Dohlman HG. Regulation of Ras Paralog Thermostability by Networks of Buried Ionizable Groups. Biochemistry. 55: 534-42. PMID 26701741 DOI: 10.1021/Acs.Biochem.5B00901 |
0.747 |
|
| 2015 |
Schrage R, Schmitz AL, Gaffal E, Annala S, Kehraus S, Wenzel D, Büllesbach KM, Bald T, Inoue A, Shinjo Y, Galandrin S, Shridhar N, Hesse M, Grundmann M, Merten N, ... ... Dohlman HG, et al. The experimental power of FR900359 to study Gq-regulated biological processes. Nature Communications. 6: 10156. PMID 26658454 DOI: 10.1038/Ncomms10156 |
0.824 |
|
| 2015 |
Venkatapurapu SP, Kelley JB, Dixit G, Pena M, Errede B, Dohlman HG, Elston TC. Modulation of receptor dynamics by the regulator of G-protein signaling Sst2. Molecular Biology of the Cell. PMID 26310439 DOI: 10.1091/Mbc.E14-12-1635 |
0.853 |
|
| 2015 |
Nagiec MJ, McCarter PC, Kelley JB, Dixit G, Elston TC, Dohlman HG. Signal inhibition by a dynamically regulated pool of monophosphorylated MAPK. Molecular Biology of the Cell. 26: 3359-71. PMID 26179917 DOI: 10.1091/Mbc.E15-01-0037 |
0.817 |
|
| 2015 |
Dohlman HG. Thematic Minireview Series: New Directions in G Protein-coupled Receptor Pharmacology. The Journal of Biological Chemistry. 290: 19469-70. PMID 26126823 DOI: 10.1074/Jbc.R115.675728 |
0.38 |
|
| 2015 |
Isom DG, Dohlman HG. Buried ionizable networks are an ancient hallmark of G protein-coupled receptor activation. Proceedings of the National Academy of Sciences of the United States of America. 112: 5702-7. PMID 25902551 DOI: 10.1073/Pnas.1417888112 |
0.759 |
|
| 2015 |
Dohlman HG. Thematic minireview series: cell biology of G protein signaling. The Journal of Biological Chemistry. 290: 6679-80. PMID 25605716 DOI: 10.1074/Jbc.R114.631093 |
0.561 |
|
| 2015 |
Kelley JB, Dixit G, Sheetz JB, Venkatapurapu SP, Elston TC, Dohlman HG. RGS proteins and septins cooperate to promote chemotropism by regulating polar cap mobility. Current Biology : Cb. 25: 275-85. PMID 25601550 DOI: 10.1016/J.Cub.2014.11.047 |
0.784 |
|
| 2015 |
English JG, Shellhammer JP, Malahe M, McCarter PC, Elston TC, Dohlman HG. MAPK feedback encodes a switch and timer for tunable stress adaptation in yeast. Science Signaling. 8: ra5. PMID 25587192 DOI: 10.1126/Scisignal.2005774 |
0.803 |
|
| 2014 |
Dixit G, Kelley JB, Houser JR, Elston TC, Dohlman HG. Cellular noise suppression by the regulator of G protein signaling Sst2. Molecular Cell. 55: 85-96. PMID 24954905 DOI: 10.1016/J.Molcel.2014.05.019 |
0.838 |
|
| 2014 |
Dixit G, Baker R, Sacks CM, Torres MP, Dohlman HG. Guanine nucleotide-binding protein (Gα) endocytosis by a cascade of ubiquitin binding domain proteins is required for sustained morphogenesis and proper mating in yeast. The Journal of Biological Chemistry. 289: 15052-63. PMID 24722989 DOI: 10.1074/Jbc.M114.566117 |
0.856 |
|
| 2014 |
Baker R, Hobbs A, Huynh M, Sasaki A, Dohlman H, Campbell SL. Abstract IA18: Activation of RAS by post-translational modification: Ubiquitination and thiol oxidation Molecular Cancer Research. 12. DOI: 10.1158/1557-3125.Rasonc14-Ia18 |
0.68 |
|
| 2013 |
Baker R, Wilkerson EM, Sumita K, Isom DG, Sasaki AT, Dohlman HG, Campbell SL. Differences in the regulation of K-Ras and H-Ras isoforms by monoubiquitination. The Journal of Biological Chemistry. 288: 36856-62. PMID 24247240 DOI: 10.1074/Jbc.C113.525691 |
0.791 |
|
| 2013 |
Clement ST, Dixit G, Dohlman HG. Regulation of yeast G protein signaling by the kinases that activate the AMPK homolog Snf1. Science Signaling. 6: ra78. PMID 24003255 DOI: 10.1126/Scisignal.2004143 |
0.852 |
|
| 2013 |
Isom DG, Sridharan V, Baker R, Clement ST, Smalley DM, Dohlman HG. Protons as second messenger regulators of G protein signaling. Molecular Cell. 51: 531-8. PMID 23954348 DOI: 10.1016/J.Molcel.2013.07.012 |
0.843 |
|
| 2013 |
Hurst JH, Dohlman HG. Dynamic ubiquitination of the mitogen-activated protein kinase kinase (MAPKK) Ste7 determines mitogen-activated protein kinase (MAPK) specificity. The Journal of Biological Chemistry. 288: 18660-71. PMID 23645675 DOI: 10.1074/Jbc.M113.475707 |
0.74 |
|
| 2013 |
Lien EC, Nagiec MJ, Dohlman HG. Proper protein glycosylation promotes mitogen-activated protein kinase signal fidelity. Biochemistry. 52: 115-24. PMID 23210626 DOI: 10.1021/Bi3009483 |
0.811 |
|
| 2013 |
Baker R, Lewis SM, Sasaki AT, Wilkerson EM, Locasale JW, Cantley LC, Kuhlman B, Dohlman HG, Campbell SL. Site-specific monoubiquitination activates Ras by impeding GTPase-activating protein function. Nature Structural & Molecular Biology. 20: 46-52. PMID 23178454 DOI: 10.1038/Nsmb.2430 |
0.697 |
|
| 2012 |
Fernandez-Piñar P, Alemán A, Sondek J, Dohlman HG, Molina M, MartÃn H. The Salmonella Typhimurium effector SteC inhibits Cdc42-mediated signaling through binding to the exchange factor Cdc24 in Saccharomyces cerevisiae. Molecular Biology of the Cell. 23: 4430-43. PMID 23015760 DOI: 10.1091/Mbc.E12-03-0243 |
0.477 |
|
| 2012 |
Hao N, Yildirim N, Nagiec MJ, Parnell SC, Errede B, Dohlman HG, Elston TC. Combined computational and experimental analysis reveals mitogen-activated protein kinase-mediated feedback phosphorylation as a mechanism for signaling specificity. Molecular Biology of the Cell. 23: 3899-910. PMID 22875986 DOI: 10.1091/Mbc.E12-04-0333 |
0.817 |
|
| 2012 |
Dohlman HG, Jones JC. Signal activation and inactivation by the Gα helical domain: a long-neglected partner in G protein signaling. Science Signaling. 5: re2. PMID 22649098 DOI: 10.1126/Scisignal.2003013 |
0.803 |
|
| 2012 |
Jones JC, Jones AM, Temple BR, Dohlman HG. Differences in intradomain and interdomain motion confer distinct activation properties to structurally similar Gα proteins. Proceedings of the National Academy of Sciences of the United States of America. 109: 7275-9. PMID 22529365 DOI: 10.1073/Pnas.1202943109 |
0.783 |
|
| 2012 |
Nagiec MJ, Dohlman HG. Checkpoints in a yeast differentiation pathway coordinate signaling during hyperosmotic stress. Plos Genetics. 8: e1002437. PMID 22242015 DOI: 10.1371/Journal.Pgen.1002437 |
0.793 |
|
| 2012 |
Cronan MR, Nakamura K, Johnson NL, Granger DA, Cuevas BD, Wang JG, Mackman N, Scott JE, Dohlman HG, Johnson GL. Defining MAP3 kinases required for MDA-MB-231 cell tumor growth and metastasis. Oncogene. 31: 3889-900. PMID 22139075 DOI: 10.1038/Onc.2011.544 |
0.756 |
|
| 2011 |
Zhu M, Torres MP, Kelley JB, Dohlman HG, Wang Y. Pheromone- and RSP5-dependent ubiquitination of the G protein beta subunit Ste4 in yeast. The Journal of Biological Chemistry. 286: 27147-55. PMID 21685393 DOI: 10.1074/Jbc.M111.254193 |
0.833 |
|
| 2011 |
Torres MP, Clement ST, Cappell SD, Dohlman HG. Cell cycle-dependent phosphorylation and ubiquitination of a G protein alpha subunit. The Journal of Biological Chemistry. 286: 20208-16. PMID 21521692 DOI: 10.1074/Jbc.M111.239343 |
0.836 |
|
| 2011 |
Cappell SD, Dohlman HG. Selective regulation of MAP kinase signaling by an endomembrane phosphatidylinositol 4-kinase. The Journal of Biological Chemistry. 286: 14852-60. PMID 21388955 DOI: 10.1074/Jbc.M110.195073 |
0.777 |
|
| 2011 |
Jones JC, Temple BR, Jones AM, Dohlman HG. Functional reconstitution of an atypical G protein heterotrimer and regulator of G protein signaling protein (RGS1) from Arabidopsis thaliana. The Journal of Biological Chemistry. 286: 13143-50. PMID 21325279 DOI: 10.1074/Jbc.M110.190355 |
0.847 |
|
| 2011 |
Jones JC, Duffy JW, Machius M, Temple BR, Dohlman HG, Jones AM. The crystal structure of a self-activating G protein alpha subunit reveals its distinct mechanism of signal initiation. Science Signaling. 4: ra8. PMID 21304159 DOI: 10.1126/Scisignal.2001446 |
0.827 |
|
| 2011 |
Machius M, Jones J, Duffy J, Temple B, Dohlman H, Jones A. Mechanism of signaling by a receptor-independent, self-activating G-protein Acta Crystallographica Section a Foundations of Crystallography. 67: C342-C343. DOI: 10.1107/S0108767311091409 |
0.779 |
|
| 2010 |
Simpson PJ, Schwappach B, Dohlman HG, Isaacson RL. Structures of Get3, Get4, and Get5 provide new models for TA membrane protein targeting. Structure (London, England : 1993). 18: 897-902. PMID 20696390 DOI: 10.1016/J.Str.2010.07.003 |
0.394 |
|
| 2010 |
Cappell SD, Baker R, Skowyra D, Dohlman HG. Systematic analysis of essential genes reveals important regulators of G protein signaling. Molecular Cell. 38: 746-57. PMID 20542006 DOI: 10.1016/J.Molcel.2010.05.026 |
0.861 |
|
| 2009 |
Dohlman HG. RGS proteins the early days. Progress in Molecular Biology and Translational Science. 86: 1-14. PMID 20374711 DOI: 10.1016/S1877-1173(09)86001-8 |
0.51 |
|
| 2009 |
Heenan EJ, Vanhooke JL, Temple BR, Betts L, Sondek JE, Dohlman HG. Structure and function of Vps15 in the endosomal G protein signaling pathway. Biochemistry. 48: 6390-401. PMID 19445518 DOI: 10.1021/Bi900621W |
0.846 |
|
| 2009 |
Torres MP, Lee MJ, Ding F, Purbeck C, Kuhlman B, Dokholyan NV, Dohlman HG. G Protein Mono-ubiquitination by the Rsp5 Ubiquitin Ligase. The Journal of Biological Chemistry. 284: 8940-50. PMID 19176477 DOI: 10.1074/Jbc.M809058200 |
0.743 |
|
| 2008 |
Dohlman HG. A scaffold makes the switch. Science Signaling. 1: pe46. PMID 18941137 DOI: 10.1126/Scisignal.142Pe46 |
0.481 |
|
| 2008 |
Hao N, Zeng Y, Elston TC, Dohlman HG. Control of MAPK specificity by feedback phosphorylation of shared adaptor protein Ste50. The Journal of Biological Chemistry. 283: 33798-802. PMID 18854322 DOI: 10.1074/Jbc.C800179200 |
0.656 |
|
| 2008 |
Behar M, Hao N, Dohlman HG, Elston TC. Dose-to-duration encoding and signaling beyond saturation in intracellular signaling networks. Plos Computational Biology. 4: e1000197. PMID 18846202 DOI: 10.1371/Journal.Pcbi.1000197 |
0.598 |
|
| 2008 |
Hao N, Nayak S, Behar M, Shanks RH, Nagiec MJ, Errede B, Hasty J, Elston TC, Dohlman HG. Regulation of cell signaling dynamics by the protein kinase-scaffold Ste5. Molecular Cell. 30: 649-56. PMID 18538663 DOI: 10.1016/J.Molcel.2008.04.016 |
0.812 |
|
| 2008 |
Lee MJ, Dohlman HG. Coactivation of G protein signaling by cell-surface receptors and an intracellular exchange factor. Current Biology : Cb. 18: 211-5. PMID 18261907 DOI: 10.1016/J.Cub.2008.01.007 |
0.693 |
|
| 2007 |
Behar M, Dohlman HG, Elston TC. Kinetic insulation as an effective mechanism for achieving pathway specificity in intracellular signaling networks. Proceedings of the National Academy of Sciences of the United States of America. 104: 16146-51. PMID 17913886 DOI: 10.1073/Pnas.0703894104 |
0.439 |
|
| 2007 |
Zeller CE, Dohlman HG. Illuminating Gbeta5 signaling. Molecular Pharmacology. 72: 810-1. PMID 17636044 DOI: 10.1124/Mol.107.040055 |
0.842 |
|
| 2007 |
Zeller CE, Parnell SC, Dohlman HG. The RACK1 ortholog Asc1 functions as a G-protein beta subunit coupled to glucose responsiveness in yeast. The Journal of Biological Chemistry. 282: 25168-76. PMID 17591772 DOI: 10.1074/Jbc.M702569200 |
0.841 |
|
| 2007 |
Behar M, Hao N, Dohlman HG, Elston TC. Mathematical and computational analysis of adaptation via feedback inhibition in signal transduction pathways. Biophysical Journal. 93: 806-21. PMID 17513354 DOI: 10.1529/Biophysj.107.107516 |
0.571 |
|
| 2007 |
Hao N, Behar M, Elston TC, Dohlman HG. Systems biology analysis of G protein and MAP kinase signaling in yeast. Oncogene. 26: 3254-66. PMID 17496920 DOI: 10.1038/Sj.Onc.1210416 |
0.684 |
|
| 2007 |
Hao N, Behar M, Parnell SC, Torres MP, Borchers CH, Elston TC, Dohlman HG. A systems-biology analysis of feedback inhibition in the Sho1 osmotic-stress-response pathway. Current Biology : Cb. 17: 659-67. PMID 17363249 DOI: 10.1016/J.Cub.2007.02.044 |
0.812 |
|
| 2007 |
Hao N, Yildirim N, Parnell S, Errede B, Elston T, Dohlman H. Modeling signal specificity by feedback inhibition The Faseb Journal. 21. DOI: 10.1096/Fasebj.21.5.A264-A |
0.655 |
|
| 2006 |
Wang Y, Dohlman HG. Regulation of G protein and mitogen-activated protein kinase signaling by ubiquitination: insights from model organisms. Circulation Research. 99: 1305-14. PMID 17158346 DOI: 10.1161/01.Res.0000251641.57410.81 |
0.655 |
|
| 2006 |
Dohlman HG, Slessareva JE. Pheromone signaling pathways in yeast. Science's Stke : Signal Transduction Knowledge Environment. 2006: cm6. PMID 17148787 DOI: 10.1126/Stke.3642006Cm6 |
0.866 |
|
| 2006 |
Slessareva JE, Dohlman HG. G protein signaling in yeast: new components, new connections, new compartments. Science (New York, N.Y.). 314: 1412-3. PMID 17138892 DOI: 10.1126/Science.1134041 |
0.847 |
|
| 2006 |
Ballon DR, Flanary PL, Gladue DP, Konopka JB, Dohlman HG, Thorner J. DEP-domain-mediated regulation of GPCR signaling responses. Cell. 126: 1079-93. PMID 16990133 DOI: 10.1016/J.Cell.2006.07.030 |
0.839 |
|
| 2006 |
Slessareva JE, Routt SM, Temple B, Bankaitis VA, Dohlman HG. Activation of the phosphatidylinositol 3-kinase Vps34 by a G protein alpha subunit at the endosome. Cell. 126: 191-203. PMID 16839886 DOI: 10.1016/J.Cell.2006.04.045 |
0.854 |
|
| 2006 |
Chasse SA, Flanary P, Parnell SC, Hao N, Cha JY, Siderovski DP, Dohlman HG. Genome-scale analysis reveals Sst2 as the principal regulator of mating pheromone signaling in the yeast Saccharomyces cerevisiae. Eukaryotic Cell. 5: 330-46. PMID 16467474 DOI: 10.1128/Ec.5.2.330-346.2006 |
0.79 |
|
| 2006 |
Wang X, Hao N, Dohlman HG, Elston TC. Bistability, stochasticity, and oscillations in the mitogen-activated protein kinase cascade. Biophysical Journal. 90: 1961-78. PMID 16361346 DOI: 10.1529/Biophysj.105.073874 |
0.685 |
|
| 2006 |
Wang Y, Dohlman HG. Pheromone-regulated sumoylation of transcription factors that mediate the invasive to mating developmental switch in yeast. The Journal of Biological Chemistry. 281: 1964-9. PMID 16306045 DOI: 10.1074/Jbc.M508985200 |
0.59 |
|
| 2005 |
Johnson GL, Dohlman HG, Graves LM. MAPK kinase kinases (MKKKs) as a target class for small-molecule inhibition to modulate signaling networks and gene expression. Current Opinion in Chemical Biology. 9: 325-31. PMID 15939336 DOI: 10.1016/J.Cbpa.2005.04.004 |
0.431 |
|
| 2005 |
Parnell SC, Marotti LA, Kiang L, Torres MP, Borchers CH, Dohlman HG. Phosphorylation of the RGS protein Sst2 by the MAP kinase Fus3 and use of Sst2 as a model to analyze determinants of substrate sequence specificity. Biochemistry. 44: 8159-66. PMID 15924435 DOI: 10.1021/Bi0503091 |
0.766 |
|
| 2005 |
Wang Y, Marotti LA, Lee MJ, Dohlman HG. Differential regulation of G protein alpha subunit trafficking by mono- and polyubiquitination. The Journal of Biological Chemistry. 280: 284-91. PMID 15519996 DOI: 10.1074/Jbc.M411624200 |
0.664 |
|
| 2004 |
Wang Y, Dohlman HG. Pheromone signaling mechanisms in yeast: a prototypical sex machine. Science (New York, N.Y.). 306: 1508-9. PMID 15567849 DOI: 10.1126/Science.1104568 |
0.656 |
|
| 2004 |
Maleri S, Ge Q, Hackett EA, Wang Y, Dohlman HG, Errede B. Persistent activation by constitutive Ste7 promotes Kss1-mediated invasive growth but fails to support Fus3-dependent mating in yeast. Molecular and Cellular Biology. 24: 9221-38. PMID 15456892 DOI: 10.1128/Mcb.24.20.9221-9238.2004 |
0.582 |
|
| 2004 |
Chasse SA, Dohlman HG. Identification of yeast pheromone pathway modulators by high-throughput agonist response profiling of a yeast gene knockout strain collection. Methods in Enzymology. 389: 399-409. PMID 15313579 DOI: 10.1016/S0076-6879(04)89024-4 |
0.44 |
|
| 2004 |
Yildirim N, Hao N, Dohlman HG, Elston TC. Mathematical modeling of RGS and G-protein regulation in yeast. Methods in Enzymology. 389: 383-98. PMID 15313578 DOI: 10.1016/S0076-6879(04)89023-2 |
0.676 |
|
| 2004 |
Wu YL, Hooks SB, Harden TK, Dohlman HG. Dominant-negative inhibition of pheromone receptor signaling by a single point mutation in the G protein alpha subunit. The Journal of Biological Chemistry. 279: 35287-97. PMID 15197187 DOI: 10.1074/Jbc.M404896200 |
0.788 |
|
| 2003 |
Chasse SA, Dohlman HG. RGS proteins: G protein-coupled receptors meet their match. Assay and Drug Development Technologies. 1: 357-64. PMID 15090201 DOI: 10.1089/154065803764958649 |
0.554 |
|
| 2003 |
Guo M, Aston C, Burchett SA, Dyke C, Fields S, Rajarao SJ, Uetz P, Wang Y, Young K, Dohlman HG. The yeast G protein alpha subunit Gpa1 transmits a signal through an RNA binding effector protein Scp160. Molecular Cell. 12: 517-24. PMID 14536090 DOI: 10.1016/S1097-2765(03)00307-1 |
0.664 |
|
| 2003 |
Hao N, Yildirim N, Wang Y, Elston TC, Dohlman HG. Regulators of G protein signaling and transient activation of signaling: experimental and computational analysis reveals negative and positive feedback controls on G protein activity. The Journal of Biological Chemistry. 278: 46506-15. PMID 12968019 DOI: 10.1074/Jbc.M308432200 |
0.766 |
|
| 2003 |
Wang Y, Ge Q, Houston D, Thorner J, Errede B, Dohlman HG. Regulation of Ste7 ubiquitination by Ste11 phosphorylation and the Skp1-Cullin-F-box complex. The Journal of Biological Chemistry. 278: 22284-9. PMID 12668671 DOI: 10.1074/Jbc.M301272200 |
0.721 |
|
| 2003 |
Sachpatzidis A, Benton BK, Manfredi JP, Wang H, Hamilton A, Dohlman HG, Lolis E. Identification of allosteric peptide agonists of CXCR4. The Journal of Biological Chemistry. 278: 896-907. PMID 12417595 DOI: 10.1074/Jbc.M204667200 |
0.307 |
|
| 2002 |
Marotti LA, Newitt R, Wang Y, Aebersold R, Dohlman HG. Direct identification of a G protein ubiquitination site by mass spectrometry. Biochemistry. 41: 5067-74. PMID 11955054 DOI: 10.1021/Bi015940Q |
0.6 |
|
| 2002 |
Burchett SA, Flanary P, Aston C, Jiang L, Young KH, Uetz P, Fields S, Dohlman HG. Regulation of stress response signaling by the N-terminal dishevelled/EGL-10/pleckstrin domain of Sst2, a regulator of G protein signaling in Saccharomyces cerevisiae. The Journal of Biological Chemistry. 277: 22156-67. PMID 11940600 DOI: 10.1074/Jbc.M202254200 |
0.558 |
|
| 2002 |
Wang Y, Dohlman HG. Pheromone-dependent ubiquitination of the mitogen-activated protein kinase kinase Ste7. The Journal of Biological Chemistry. 277: 15766-72. PMID 11864977 DOI: 10.1074/Jbc.M111733200 |
0.66 |
|
| 2002 |
Dohlman HG. G proteins and pheromone signaling. Annual Review of Physiology. 64: 129-52. PMID 11826266 DOI: 10.1146/Annurev.Physiol.64.081701.133448 |
0.57 |
|
| 2002 |
Garrison TR, Apanovitch DM, Dohlman HG. Purification of RGS protein, Sst2, from Saccharomyces cerevisiae and Escherichia coli. Methods in Enzymology. 344: 632-47. PMID 11771416 DOI: 10.1016/S0076-6879(02)44745-3 |
0.785 |
|
| 2002 |
Hoffman GA, Garrison TR, Dohlman HG. Analysis of RGS proteins in Saccharomyces cerevisiae. Methods in Enzymology. 344: 617-31. PMID 11771415 DOI: 10.1016/S0076-6879(02)44744-1 |
0.8 |
|
| 2001 |
Dohlman HG, Thorner JW. Regulation of G protein-initiated signal transduction in yeast: paradigms and principles. Annual Review of Biochemistry. 70: 703-54. PMID 11395421 DOI: 10.1146/Annurev.Biochem.70.1.703 |
0.692 |
|
| 2001 |
Burchett SA, Scott A, Errede B, Dohlman HG. Identification of Novel Pheromone-response Regulators through Systematic Overexpression of 120 Protein Kinases in Yeast Journal of Biological Chemistry. 276: 26472-26478. PMID 11337509 DOI: 10.1074/Jbc.M103436200 |
0.507 |
|
| 2000 |
Ehrhard KN, Jacoby JJ, Fu XY, Jahn R, Dohlman HG. Use of G-protein fusions to monitor integral membrane protein-protein interactions in yeast. Nature Biotechnology. 18: 1075-9. PMID 11017046 DOI: 10.1038/80274 |
0.484 |
|
| 2000 |
Hoffman GA, Garrison TR, Dohlman HG. Endoproteolytic processing of Sst2, a multidomain regulator of G protein signaling in yeast Journal of Biological Chemistry. 275: 37533-37541. PMID 10982801 DOI: 10.1074/Jbc.M005751200 |
0.831 |
|
| 2000 |
Flanary PL, DiBello PR, Estrada P, Dohlman HG. Functional analysis of Plp1 and Plp2, two homologues of phosducin in yeast Journal of Biological Chemistry. 275: 18462-18469. PMID 10749875 DOI: 10.1074/Jbc.M002163200 |
0.472 |
|
| 2000 |
Li F, Flanary PL, Altieri DC, Dohlman HG. Cell division regulation by BIR1, a member of the inhibitor of apoptosis family in yeast Journal of Biological Chemistry. 275: 6707-6711. PMID 10702224 DOI: 10.1074/Jbc.275.10.6707 |
0.37 |
|
| 1999 |
Garrison TR, Zhang Y, Pausch M, Apanovitch D, Aebersold R, Dohlman HG. Feedback phosphorylation of an RGS protein by MAP kinase in yeast Journal of Biological Chemistry. 274: 36387-36391. PMID 10593933 DOI: 10.1074/Jbc.274.51.36387 |
0.826 |
|
| 1998 |
Apanovitch DM, Iiri T, Karasawa T, Bourne HR, Dohlman HG. Second site suppressor mutations of a GTPase-deficient G-protein alpha-subunit. Selective inhibition of Gbeta gamma-mediated signaling. The Journal of Biological Chemistry. 273: 28597-602. PMID 9786851 DOI: 10.1074/Jbc.273.44.28597 |
0.404 |
|
| 1998 |
Dohlman HG, Song J, Apanovitch DM, DiBello PR, Gillen KM. Regulation of G protein signalling in yeast Seminars in Cell and Developmental Biology. 9: 135-141. PMID 9599408 DOI: 10.1006/Scdb.1998.0218 |
0.568 |
|
| 1998 |
Lan KL, Sarvazyan NA, Taussig R, Mackenzie RG, DiBello PR, Dohlman HG, Neubig RR. A point mutation in Gα(o) and Gα(i1) blocks interaction with regulator of G protein signaling proteins Journal of Biological Chemistry. 273: 12794-12797. PMID 9582306 DOI: 10.1074/Jbc.273.21.12794 |
0.457 |
|
| 1998 |
Apanovitch DM, Slep KC, Sigler PB, Dohlman HG. Sst2 is a GTPase-activating protein for Gpa1: purification and characterization of a cognate RGS-Galpha protein pair in yeast. Biochemistry. 37: 4815-22. PMID 9537998 DOI: 10.1021/Bi9729965 |
0.514 |
|
| 1998 |
DiBello PR, Garrison TR, Apanovitch DM, Hoffman G, Shuey DJ, Mason K, Cockett MI, Dohlman HG. Selective uncoupling of RGS action by a single point mutation in the G protein alpha-subunit. The Journal of Biological Chemistry. 273: 5780-4. PMID 9488712 DOI: 10.1074/Jbc.273.10.5780 |
0.849 |
|
| 1997 |
Gold SJ, Ni YG, Dohlman HG, Nestler EJ. Regulators of G-protein signaling (RGS) proteins: Region-specific expression of nine subtypes in rat brain Journal of Neuroscience. 17: 8024-8037. PMID 9315921 DOI: 10.1523/Jneurosci.17-20-08024.1997 |
0.401 |
|
| 1997 |
Dohlman HG, Thorner J. RGS proteins and signaling by heterotrimeric G proteins. The Journal of Biological Chemistry. 272: 3871-4. PMID 9064301 DOI: 10.1074/Jbc.272.7.3871 |
0.699 |
|
| 1997 |
Apanovitch PM, Slep K, Sigler PB, Dohlman HG. Purification and characterization of SST2: Regulation of the gtpase activity of a G protein (GPA1) from the yeast saccharomyces cerevisiae Faseb Journal. 11: A1304. |
0.427 |
|
| 1996 |
Kübler E, Dohlman HG, Lisanti MP. Identification of Triton X-100 insoluble membrane domains in the yeast Saccharomyces cerevisiae: Lipid requirements for targeting of heterotrimeric G-protein subunits Journal of Biological Chemistry. 271: 32975-32980. PMID 8955141 DOI: 10.1074/Jbc.271.51.32975 |
0.426 |
|
| 1996 |
Song J, Dohlman HG. Partial constitutive activation of pheromone responses by a palmitoylation-site mutant of a G protein α subunit in yeast Biochemistry. 35: 14806-14817. PMID 8942643 DOI: 10.1021/Bi961846B |
0.44 |
|
| 1996 |
Dohlman HG, Song J, Ma D, Courchesne WE, Thorner J. Sst2, a negative regulator of pheromone signaling in the yeast Saccharomyces cerevisiae: expression, localization, and genetic interaction and physical association with Gpa1 (the G-protein alpha subunit). Molecular and Cellular Biology. 16: 5194-209. PMID 8756677 DOI: 10.1128/Mcb.16.9.5194 |
0.684 |
|
| 1996 |
Song J, Hirschman J, Gunn K, Dohlman HG. Regulation of membrane and subunit interactions by N-myristoylation of a G protein alpha subunit in yeast. The Journal of Biological Chemistry. 271: 20273-83. PMID 8702760 DOI: 10.1074/Jbc.271.34.20273 |
0.454 |
|
| 1995 |
Dohlman HG, Apaniesk D, Chen Y, Song J, Nusskern D. Inhibition of G-protein signaling by dominant gain-of-function mutations in Sst2p, a pheromone desensitization factor in Saccharomyces cerevisiae Molecular and Cellular Biology. 15: 3635-3643. PMID 7791771 DOI: 10.1128/Mcb.15.7.3635 |
0.481 |
|
| 1993 |
Dohlman HG, Goldsmith P, Spiegel AM, Thorner J. Pheromone action regulates G-protein alpha-subunit myristoylation in the yeast Saccharomyces cerevisiae. Proceedings of the National Academy of Sciences of the United States of America. 90: 9688-92. PMID 8415763 DOI: 10.1073/Pnas.90.20.9688 |
0.621 |
|
| 1993 |
Dohlman HG. Hormone signal response system [6] Nature. 366: 307-308. PMID 8247122 DOI: 10.1038/366307B0 |
0.346 |
|
| 1993 |
Kuchler K, Dohlman HG, Thorner J. The a-factor transporter (STE6 gene product) and cell polarity in the yeast Saccharomyces cerevisiae. The Journal of Cell Biology. 120: 1203-15. PMID 7679674 DOI: 10.1083/Jcb.120.5.1203 |
0.518 |
|
| 1991 |
Dohlman HG, Thorner J, Caron MG, Lefkowitz RJ. Model systems for the study of seven-transmembrane-segment receptors. Annual Review of Biochemistry. 60: 653-88. PMID 1652922 DOI: 10.1146/annurev.bi.60.070191.003253 |
0.732 |
|
| 1990 |
Benovic JL, Onorato J, Lohse MJ, Dohlman HG, Staniszewski C, Caron MG, Lefkowitz RJ. Synthetic peptides of the hamster beta 2-adrenoceptor as substrates and inhibitors of the beta-adrenoceptor kinase. British Journal of Clinical Pharmacology. 30: 3S-12S. PMID 2176526 DOI: 10.1111/J.1365-2125.1990.Tb05462.X |
0.691 |
|
| 1990 |
King K, Dohlman HG, Thorner J, Caron MG, Lefkowitz RJ. Control of yeast mating signal transduction by a mammalian beta 2-adrenergic receptor and Gs alpha subunit. Science (New York, N.Y.). 250: 121-3. PMID 2171146 DOI: 10.1126/Science.2171146 |
0.805 |
|
| 1990 |
Dohlman HG, Caron MG, DeBlasi A, Frielle T, Lefkowitz RJ. Role of extracellular disulfide-bonded cysteines in the ligand binding function of the beta 2-adrenergic receptor. Biochemistry. 29: 2335-42. PMID 2159799 DOI: 10.1021/Bi00461A018 |
0.782 |
|
| 1988 |
Lefkowitz RJ, Kobilka BK, Benovic JL, Bouvier M, Cotecchia S, Hausdorff WP, Dohlman HG, Regan JW, Caron MG. Molecular biology of adrenergic receptors. Cold Spring Harbor Symposia On Quantitative Biology. 53: 507-14. PMID 2855490 DOI: 10.1101/Sqb.1988.053.01.058 |
0.778 |
|
| 1988 |
Dohlman HG, Caron MG, Strader CD, Amlaiky N, Lefkowitz RJ. Identification and sequence of a binding site peptide of the beta 2-adrenergic receptor. Biochemistry. 27: 1813-7. PMID 2837273 DOI: 10.1021/Bi00406A002 |
0.596 |
|
| 1988 |
Dohlman HG, Caron MG, Strader CD, Amlaiky N, Lefkowitz RJ. Identification and sequence of a binding site peptide of the .beta.2-adrenergic receptor [Erratum to document cited in CA108(15):126956h] Biochemistry. 27: 8508-8508. DOI: 10.1021/Bi00422A034 |
0.56 |
|
| 1987 |
Dohlman HG, Caron MG, Lefkowitz RJ. A family of receptors coupled to guanine nucleotide regulatory proteins. Biochemistry. 26: 2657-64. PMID 3038163 DOI: 10.1021/Bi00384A001 |
0.629 |
|
| 1987 |
Kobilka BK, Frielle T, Dohlman HG, Bolanowski MA, Dixon RA, Keller P, Caron MG, Lefkowitz RJ. Delineation of the intronless nature of the genes for the human and hamster beta 2-adrenergic receptor and their putative promoter regions. The Journal of Biological Chemistry. 262: 7321-7. PMID 3034889 |
0.786 |
|
| 1987 |
Kobilka BK, Dixon RA, Frielle T, Dohlman HG, Bolanowski MA, Sigal IS, Yang-Feng TL, Francke U, Caron MG, Lefkowitz RJ. cDNA for the human beta 2-adrenergic receptor: a protein with multiple membrane-spanning domains and encoded by a gene whose chromosomal location is shared with that of the receptor for platelet-derived growth factor. Proceedings of the National Academy of Sciences of the United States of America. 84: 46-50. PMID 3025863 DOI: 10.1073/Pnas.84.1.46 |
0.795 |
|
| 1987 |
Dohlman HG, Caron MG, Lefkowitz RJ. Structure and function of the beta 2-adrenergic receptor--homology with rhodopsin. Kidney International. Supplement. 23: S2-13. PMID 2831423 |
0.401 |
|
| 1987 |
Dohlman HG, Bouvier M, Benovic JL, Caron MG, Lefkowitz RJ. The multiple membrane spanning topography of the beta 2-adrenergic receptor. Localization of the sites of binding, glycosylation, and regulatory phosphorylation by limited proteolysis. The Journal of Biological Chemistry. 262: 14282-8. PMID 2821000 |
0.689 |
|
| 1986 |
Dixon RA, Kobilka BK, Strader DJ, Benovic JL, Dohlman HG, Frielle T, Bolanowski MA, Bennett CD, Rands E, Diehl RE, Mumford RA, Slater EE, Sigal IS, Caron MG, Lefkowitz RJ, et al. Cloning of the gene and cDNA for mammalian beta-adrenergic receptor and homology with rhodopsin. Nature. 321: 75-9. PMID 3010132 DOI: 10.1038/321075A0 |
0.785 |
|
| 1984 |
García-Sáinz JA, Boyer JL, Michel T, Sawyer D, Stiles GL, Dohlman H, Lefkowitz RJ. Effect of pertussis toxin on alpha 2-adrenoceptors: decreased formation of the high-affinity state for agonists. Febs Letters. 172: 95-8. PMID 6329826 DOI: 10.1016/0014-5793(84)80881-9 |
0.47 |
|
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