Juan C. Troncoso, MD - Related publications

Affiliations: 
Pathology Johns Hopkins University School of Medicine, Baltimore, MD, United States 
Area:
human neurodegenerative disorders, in particular Alzheimer's disease
Website:
http://www.alzresearch.org/team.cfm?ID=2
NOTE: We are testing a new system for identifying relevant work based on semantic analysis that identifies similarities between recently published papers and the current author's publications. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches.
50 most relevant papers in past 60 days:
Year Citation  Score
2020 d'Abramo C, D'Adamio L, Giliberto L. Significance of Blood and Cerebrospinal Fluid Biomarkers for Alzheimer's Disease: Sensitivity, Specificity and Potential for Clinical Use. Journal of Personalized Medicine. 10. PMID 32911755 DOI: 10.3390/jpm10030116   
2020 Edler MK, Munger EL, Meindl RS, Hopkins WD, Ely JJ, Erwin JM, Mufson EJ, Hof PR, Sherwood CC, Raghanti MA. Neuron loss associated with age but not Alzheimer's disease pathology in the chimpanzee brain. Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences. 375: 20190619. PMID 32951541 DOI: 10.1098/rstb.2019.0619   
2020 Ray WJ, Buggia-Prevot V. Novel Targets for Alzheimer's Disease: A View Beyond Amyloid. Annual Review of Medicine. PMID 32867590 DOI: 10.1146/annurev-med-052919-120219   
2020 Mishra J, Kumar B, Pandey M, Pottoo FH, Fayaz F, Khan FA, Sahoo PK. Carbon Nano Tubes: Novel drug delivery system in amelioration of Alzheimer's disease. Combinatorial Chemistry & High Throughput Screening. PMID 32957874 DOI: 10.2174/1386207323999200918112538   
2020 Mold MJ, O'Farrell A, Morris B, Exley C. Aluminum and Neurofibrillary Tangle Co-Localization in Familial Alzheimer's Disease and Related Neurological Disorders. Journal of Alzheimer's Disease : Jad. PMID 32925074 DOI: 10.3233/JAD-200838   
2020 Arya R, Paliwal S, Gupta SP, Sharma S, Madan K, Mishra A, Verma K, Chauhan N. In-silico studies and Biological activity of potential BACE-1 Inhibitors. Combinatorial Chemistry & High Throughput Screening. PMID 32957879 DOI: 10.2174/1386207323999200918151331   
2020 Anu K R, Das S, Joseph A, Shenoy GG, Alex AT, Mudgal J. Neurodegenerative Pathways in Alzheimer's Disease: A Review. Current Neuropharmacology. PMID 32851951 DOI: 10.2174/1570159X18666200807130637   
2020 Kang SS, Ahn EH, Ye K. Delta-secretase cleavage of Tau mediates its pathology and propagation in Alzheimer's disease. Experimental & Molecular Medicine. PMID 32859953 DOI: 10.1038/s12276-020-00494-7   
2020 Narayanan SE, Sekhar N, Rajamma RG, Marathakam A, Al Mamun A, Uddin MS, Mathew B. Exploring the Role of Aggregated Proteomes in the Pathogenesis of Alzheimer's Disease. Current Protein & Peptide Science. PMID 32957903 DOI: 10.2174/1389203721666200921152246   
2020 Garcia-Leon JA, Caceres-Palomo L, Sanchez-Mejias E, Mejias-Ortega M, Nuñez-Diaz C, Fernandez-Valenzuela JJ, Sanchez-Varo R, Davila JC, Vitorica J, Gutierrez A. Human Pluripotent Stem Cell-Derived Neural Cells as a Relevant Platform for Drug Screening in Alzheimer's Disease. International Journal of Molecular Sciences. 21. PMID 32962164 DOI: 10.3390/ijms21186867   
2020 Bowerman M. Recent Advances and Future Perspectives in the Development of Therapeutic Approaches for Neurodegenerative Diseases. Brain Sciences. 10. PMID 32932920 DOI: 10.3390/brainsci10090633   
2020 Henríquez G, Gomez A, Guerrero ED, Narayan M. The Potential Role of Natural Polyphenols Against Protein Aggregation Toxicity: In Vitro, In Vivo, and Clinical studies. Acs Chemical Neuroscience. PMID 32822152 DOI: 10.1021/acschemneuro.0c00381   
2020 Dhanwani R, Pham J, Premlal ALR, Frazier A, Kumar A, Pero ME, Bartolini F, Dutra JR, Marder KS, Peters B, Sulzer D, Sette A, Lindestam Arlehamn CS. T Cell Responses to Neural Autoantigens Are Similar in Alzheimer's Disease Patients and Age-Matched Healthy Controls. Frontiers in Neuroscience. 14: 874. PMID 32982670 DOI: 10.3389/fnins.2020.00874   
2020 Shen XN, Li JQ, Wang HF, Li HQ, Huang YY, Yang YX, Tan L, Dong Q, Yu JT, . Plasma amyloid, tau, and neurodegeneration biomarker profiles predict Alzheimer's disease pathology and clinical progression in older adults without dementia. Alzheimer's & Dementia (Amsterdam, Netherlands). 12: e12104. PMID 33005724 DOI: 10.1002/dad2.12104   
2020 Shen XN, Li JQ, Wang HF, Li HQ, Huang YY, Yang YX, Tan L, Dong Q, Yu JT, . Plasma amyloid, tau, and neurodegeneration biomarker profiles predict Alzheimer's disease pathology and clinical progression in older adults without dementia. Alzheimer's & Dementia (Amsterdam, Netherlands). 12: e12104. PMID 33005724 DOI: 10.1002/dad2.12104   
2020 Yeung CHC, Lau KWD, Au Yeung SL, Schooling CM. Amyloid, tau and risk of Alzheimer's disease: a Mendelian randomization study. European Journal of Epidemiology. PMID 32929646 DOI: 10.1007/s10654-020-00683-8   
2020 Gupta VB, Chitranshi N, Haan JD, Mirzaei M, You Y, Lim JK, Basavarajappa D, Godinez A, Di Angelantonio S, Sachdev P, Salekdeh GH, Bouwman F, Graham S, Gupta V. Retinal changes in Alzheimer's disease- integrated prospects of imaging, functional and molecular advances. Progress in Retinal and Eye Research. 100899. PMID 32890742 DOI: 10.1016/j.preteyeres.2020.100899   
2020 Muralidar S, Ambi SV, Sekaran S, Thirumalai D, Palaniappan B. Role of tau protein in Alzheimer's disease: The prime pathological player. International Journal of Biological Macromolecules. PMID 32784025 DOI: 10.1016/j.ijbiomac.2020.07.327   
2020 von Saucken VE, Jay TR, Landreth GE. The effect of amyloid on microglia-neuron interactions before plaque onset occurs independently of TREM2 in a mouse model of Alzheimer's disease. Neurobiology of Disease. 105072. PMID 32890775 DOI: 10.1016/j.nbd.2020.105072   
2020 Gao J, Chen X, Ma T, He B, Li P, Zhao Y, Ma Y, Zhuang J, Yin Y. PEG-Ceramide Nanomicelles Induce Autophagy and Degrade Tau Proteins in N2a Cells. International Journal of Nanomedicine. 15: 6779-6789. PMID 32982233 DOI: 10.2147/IJN.S258311   
2020 Al Mamun A, Rahman MM, Zaman S, Munira MS, Uddin MS, Rauf A, Banu N, Ashraf GM. Molecular Insight into the Crosstalk of UPS Components and Alzheimer's Disease. Current Protein & Peptide Science. PMID 32964822 DOI: 10.2174/1389203721666200923153406   
2020 Chiasseu M, Fesharaki A, Saito T, Saido TC, Strittmatter SM. Gene-environment interaction promotes Alzheimer's risk as revealed by synergy of repeated mild traumatic brain injury and mouse App knock-in. Neurobiology of Disease. 145: 105059. PMID 32858147 DOI: 10.1016/j.nbd.2020.105059   
2020 Wei W, Wang Y, Liu Y, Dai CL, Tung YC, Liu F, Iqbal K. Prenatal to early postnatal neurotrophic treatment prevents Alzheimer-like behavior and pathology in mice. Alzheimer's Research & Therapy. 12: 102. PMID 32854771 DOI: 10.1186/s13195-020-00666-7   
2020 Zamudio F, Loon AR, Smeltzer S, Benyamine K, Navalpur Shanmugam NK, Stewart NJF, Lee DC, Nash K, Selenica MB. TDP-43 mediated blood-brain barrier permeability and leukocyte infiltration promote neurodegeneration in a low-grade systemic inflammation mouse model. Journal of Neuroinflammation. 17: 283. PMID 32979923 DOI: 10.1186/s12974-020-01952-9   
2020 Ma WH, Chen AF, Xie XY, Huang YS. Sigma ligands as potent inhibitors of Aβ and AβOs in neurons and promising therapeutic agents of Alzheimer's disease. Neuropharmacology. 108342. PMID 33045243 DOI: 10.1016/j.neuropharm.2020.108342   
2020 Bennett DA, Knopman DS. Extending AD biomarker studies into the Hispanic community. Neurology. PMID 32847949 DOI: 10.1212/WNL.0000000000010714   
2020 Haddadi R, Shahidi Z, Eyvari-Brooshghalan S. Silymarin and neurodegenerative diseases: Therapeutic potential and basic molecular mechanisms. Phytomedicine : International Journal of Phytotherapy and Phytopharmacology. 79: 153320. PMID 32920285 DOI: 10.1016/j.phymed.2020.153320   
2020 Corsetti V, Borreca A, Latina V, Giacovazzo G, Pignataro A, Krashia P, Natale F, Cocco S, Rinaudo M, Malerba F, Florio R, Ciarapica R, Coccurello R, D'Amelio M, Ammassari-Teule M, et al. Passive immunotherapy for N-truncated tau ameliorates the cognitive deficits in two mouse Alzheimer's disease models. Brain Communications. 2: fcaa039. PMID 32954296 DOI: 10.1093/braincomms/fcaa039   
2020 Barman NC, Khan NM, Islam M, Nain Z, Roy RK, Haque A, Barman SK. CRISPR-Cas9: A Promising Genome Editing Therapeutic Tool for Alzheimer's Disease-A Narrative Review. Neurology and Therapy. PMID 33089409 DOI: 10.1007/s40120-020-00218-z   
2020 Peng SY, Wu X, Lu T, Cui G, Chen G. Research progress of hydrogen sulfide in Alzheimer's disease from laboratory to hospital: a narrative review. Medical Gas Research. 10: 125-129. PMID 33004710 DOI: 10.4103/2045-9912.296043   
2020 Peng SY, Wu X, Lu T, Cui G, Chen G. Research progress of hydrogen sulfide in Alzheimer's disease from laboratory to hospital: a narrative review. Medical Gas Research. 10: 125-129. PMID 33004710 DOI: 10.4103/2045-9912.296043   
2020 De La-Rocque S, Moretto E, Butnaru I, Schiavo G. Knockin' on heaven's door: Molecular mechanisms of neuronal tau uptake. Journal of Neurochemistry. PMID 32770783 DOI: 10.1111/jnc.15144   
2020 Chen XQ, Salehi A, Pearn ML, Overk C, Nguyen PD, Kleschevnikov AM, Maccecchini M, Mobley WC. Targeting increased levels of APP in Down syndrome: Posiphen-mediated reductions in APP and its products reverse endosomal phenotypes in the Ts65Dn mouse model. Alzheimer's & Dementia : the Journal of the Alzheimer's Association. PMID 32975365 DOI: 10.1002/alz.12185   
2020 Lin G, Ji K, Li S, Ma W, Pan X. The Genetics Analysis of Molecular Pathogenesis for Alzheimer's Disease. European Neurology. 1-10. PMID 33027797 DOI: 10.1159/000509799   
2020 Houben S, de Fisenne MA, Ando K, Vanden Dries V, Poncelet L, Yilmaz Z, Mansour S, De Decker R, Brion JP, Leroy K. Intravenous Injection of PHF-Tau Proteins From Alzheimer Brain Exacerbates Neuroinflammation, Amyloid Beta, and Tau Pathologies in 5XFAD Transgenic Mice. Frontiers in Molecular Neuroscience. 13: 106. PMID 32765217 DOI: 10.3389/fnmol.2020.00106   
2020 Clark JN, Whiting A, McCaffery P. Retinoic acid receptor targeted drugs in neurodegenerative disease. Expert Opinion On Drug Metabolism & Toxicology. PMID 32799572 DOI: 10.1080/17425255.2020.1811232   
2020 Brosseron F, Kleemann K, Kolbe CC, Santarelli F, Castro-Gomez S, Tacik P, Latz E, Jessen F, Heneka MT. Interrelations of Alzheimer´s disease candidate biomarkers neurogranin, fatty acid binding protein 3 and ferritin to neurodegeneration and neuroinflammation. Journal of Neurochemistry. PMID 32894885 DOI: 10.1111/jnc.15175   
2020 Costa AS, Agostini S, Guerini FR, Mancuso R, Clerici M, Pandey JP. Relation between FCGRIIB rs1050501 and HSV-1 specific IgG antibodies in Alzheimer's disease. Journal of Translational Medicine. 18: 325. PMID 32859213 DOI: 10.1186/s12967-020-02495-6   
2020 Poon CH, Wang Y, Fung ML, Zhang C, Lim LW. Rodent Models of Amyloid-Beta Feature of Alzheimer's Disease: Development and Potential Treatment Implications. Aging and Disease. 11: 1235-1259. PMID 33014535 DOI: 10.14336/AD.2019.1026   
2020 Ikram M, Park TJ, Ali T, Kim MO. Antioxidant and Neuroprotective Effects of Caffeine against Alzheimer's and Parkinson's Disease: Insight into the Role of Nrf-2 and A2AR Signaling. Antioxidants (Basel, Switzerland). 9. PMID 32971922 DOI: 10.3390/antiox9090902   
2020 Thomas DX, Bajaj S, McRae-McKee K, Hadjichrysanthou C, Anderson RM, Collinge J. Association of TDP-43 proteinopathy, cerebral amyloid angiopathy, and Lewy bodies with cognitive impairment in individuals with or without Alzheimer's disease neuropathology. Scientific Reports. 10: 14579. PMID 32883971 DOI: 10.1038/s41598-020-71305-2   
2020 Dadar M, Camicioli R, Duchesne S, Collins DL, . The temporal relationships between white matter hyperintensities, neurodegeneration, amyloid beta, and cognition. Alzheimer's & Dementia (Amsterdam, Netherlands). 12: e12091. PMID 33083512 DOI: 10.1002/dad2.12091   
2020 Shi WY, Wang ZT, Sun FR, Ma YH, Xu W, Shen XN, Dong Q, Tan L, Yu JT, Yu Y, . High pulse pressure is a risk factor for prodromal Alzheimer's disease: a longitudinal study. Aging. 12. PMID 32960784 DOI: 10.18632/aging.103678   
2020 Park KHJ, Barrett T. Gliosis Precedes Amyloid-β Deposition and Pathological Tau Accumulation in the Neuronal Cell Cycle Re-Entry Mouse Model of Alzheimer's Disease. Journal of Alzheimer's Disease Reports. 4: 243-253. PMID 32904753 DOI: 10.3233/ADR-200170   
2020 Weigand AJ, Thomas KR, Bangen KJ, Eglit GML, Delano-Wood L, Gilbert PE, Brickman AM, Bondi MW, . APOE interacts with tau PET to influence memory independently of amyloid PET in older adults without dementia. Alzheimer's & Dementia : the Journal of the Alzheimer's Association. PMID 32886451 DOI: 10.1002/alz.12173   
2020 Siano G, Varisco M, Scarlatti A, Caiazza MC, Dunville K, Cremisi F, Costa M, Pancrazi L, Di Primio C, Cattaneo A. Gene expression of disease-related genes in Alzheimer's disease is impaired by Tau aggregation. Journal of Molecular Biology. PMID 33058882 DOI: 10.1016/j.jmb.2020.10.009   
2020 Hascup ER, Hascup KN. Toward refining Alzheimer's disease into overlapping subgroups. Alzheimer's & Dementia (New York, N. Y.). 6: e12070. PMID 32885025 DOI: 10.1002/trc2.12070   
2020 Qu X, Guan P, Han L, Wang Z, Huang X. Levistolide A Attenuates Alzheimer's Pathology Through Activation of the PPARγ Pathway. Neurotherapeutics : the Journal of the American Society For Experimental Neurotherapeutics. PMID 33034847 DOI: 10.1007/s13311-020-00943-1   
2020 Cecarini V, Bonfili L, Gogoi O, Lawrence S, Venanzi FM, Azevedo V, Mancha-Agresti P, Drumond MM, Rossi G, Berardi S, Galosi L, Cuccioloni M, Angeletti M, Suchodolski JS, Pilla R, et al. Neuroprotective effects of p62(SQSTM1)-engineered lactic acid bacteria in Alzheimer's disease: a pre-clinical study. Aging. 12. PMID 32855357 DOI: 10.18632/aging.103900   
2020 Li S, Wang C, Wang W, Tan J. Trait anxiety, a personality risk factor associated with Alzheimer's Disease. Progress in Neuro-Psychopharmacology & Biological Psychiatry. 110124. PMID 33035604 DOI: 10.1016/j.pnpbp.2020.110124