Xiaolu Yang - Publications

Affiliations: 
Cell and Molecular Biology University of Pennsylvania, Philadelphia, PA, United States 
Area:
Cell Biology, Neuroscience Biology, Biochemistry

66 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2020 Lu Z, Bi J, Sun Y, Yang X, Wan X. Polyglutamine protein in tumor cells sensitizes tumor cells to natural killer cell cytolysis. Molecular Immunology. 124: 153-160. PMID 32580073 DOI: 10.1016/J.Molimm.2020.06.008  0.353
2020 Liu Y, Tao S, Liao L, Li Y, Li H, Li Z, Lin L, Wan X, Yang X, Chen L. TRIM25 promotes the cell survival and growth of hepatocellular carcinoma through targeting Keap1-Nrf2 pathway. Nature Communications. 11: 348. PMID 31953436 DOI: 10.1038/S41467-019-14190-2  0.346
2019 Yan D, Wang J, Sun H, Zamani A, Zhang H, Chen W, Tang A, Ruan Q, Yang X, Chen YH, Wan X. TIPE2 specifies the functional polarization of myeloid-derived suppressor cells during tumorigenesis. The Journal of Experimental Medicine. PMID 31662347 DOI: 10.1084/Jem.20182005  0.36
2019 Chen Z, Ji Z, Ngiow SF, Manne S, Cai Z, Huang AC, Johnson J, Staupe RP, Bengsch B, Xu C, Yu S, Kurachi M, Herati RS, Vella LA, Baxter AE, ... ... Yang X, et al. TCF-1-Centered Transcriptional Network Drives an Effector versus Exhausted CD8 T Cell-Fate Decision. Immunity. PMID 31606264 DOI: 10.1016/J.Immuni.2019.09.013  0.308
2019 Weng L, Wang Q, Yu S, Yang X, Lynch DR, Mesaros C, Blair IA. Evaluation of antibodies for western blot analysis of frataxin protein isoforms. Journal of Immunological Methods. PMID 31279523 DOI: 10.1016/J.Jim.2019.07.001  0.316
2019 Zhang P, Cao L, Zhou R, Yang X, Wu M. The lncRNA Neat1 promotes activation of inflammasomes in macrophages. Nature Communications. 10: 1495. PMID 30940803 DOI: 10.1038/S41467-019-09482-6  0.381
2019 Chen L, Yang X. TRIM11 cooperates with HSF1 to suppress the anti-tumor effect of proteotoxic stress drugs. Cell Cycle (Georgetown, Tex.). 18: 60-68. PMID 30563406 DOI: 10.1080/15384101.2018.1558870  0.35
2018 Li L, Li L, Li W, Chen T, Bin Zou, Zhao L, Wang H, Wang X, Xu L, Liu X, Wang D, Li B, Mak TW, Du W, Yang X, et al. TAp73-induced phosphofructokinase-1 transcription promotes the Warburg effect and enhances cell proliferation. Nature Communications. 9: 4683. PMID 30409970 DOI: 10.1038/S41467-018-07127-8  0.342
2018 Chen L, Zhu G, Johns EM, Yang X. TRIM11 activates the proteasome and promotes overall protein degradation by regulating USP14. Nature Communications. 9: 1223. PMID 29581427 DOI: 10.1038/S41467-018-03499-Z  0.434
2017 Chen L, Guo L, Yang X. Augmented capacity to clear misfolded proteins: An intrinsic characteristic of tumor cells? Molecular & Cellular Oncology. 4: e1337548. PMID 29057304 DOI: 10.1080/23723556.2017.1337548  0.325
2017 Chen L, Brewer MD, Guo L, Wang R, Jiang P, Yang X. Enhanced Degradation of Misfolded Proteins Promotes Tumorigenesis. Cell Reports. 18: 3143-3154. PMID 28355566 DOI: 10.1016/J.Celrep.2017.03.010  0.387
2016 Feng Z, Wang L, Sun Y, Jiang Z, Domsic J, An C, Xing B, Tian J, Liu X, Metz DC, Yang X, Marmorstein R, Ma X, Hua X. Menin and Daxx Interact to Control Neuroendocrine Tumors via Epigenetic Regulation of Membrane Metallo-Endopeptidase. Cancer Research. PMID 27872097 DOI: 10.1158/0008-5472.Can-16-1567  0.356
2016 Guo L, Prall W, Yang X. Assays for the Degradation of Misfolded Proteins in Cells. Journal of Visualized Experiments : Jove. PMID 27684355 DOI: 10.3791/54266  0.363
2016 Liu C, Stonestrom AJ, Christian T, Yong J, Takase R, Hou YM, Yang X. Molecular Basis and Consequences of the Cytochrome c-tRNA Interaction. The Journal of Biological Chemistry. PMID 26961879 DOI: 10.1074/Jbc.M115.697789  0.345
2014 Guo L, Giasson BI, Glavis-Bloom A, Brewer MD, Shorter J, Gitler AD, Yang X. A cellular system that degrades misfolded proteins and protects against neurodegeneration. Molecular Cell. 55: 15-30. PMID 24882209 DOI: 10.1016/J.Molcel.2014.04.030  0.378
2014 Yang W, Cooke M, Duckett CS, Yang X, Dorsey JF. Distinctive effects of the cellular inhibitor of apoptosis protein c-IAP2 through stabilization by XIAP in glioblastoma multiforme cells. Cell Cycle (Georgetown, Tex.). 13: 992-1005. PMID 24552816 DOI: 10.4161/Cc.27880  0.409
2013 Jiang P, Du W, Yang X. A critical role of glucose-6-phosphate dehydrogenase in TAp73-mediated cell proliferation. Cell Cycle (Georgetown, Tex.). 12: 3720-6. PMID 24270845 DOI: 10.4161/Cc.27267  0.358
2013 Du W, Jiang P, Mancuso A, Stonestrom A, Brewer MD, Minn AJ, Mak TW, Wu M, Yang X. TAp73 enhances the pentose phosphate pathway and supports cell proliferation. Nature Cell Biology. 15: 991-1000. PMID 23811687 DOI: 10.1038/Ncb2789  0.352
2013 Ranaweera RS, Yang X. Auto-ubiquitination of Mdm2 enhances its substrate ubiquitin ligase activity. The Journal of Biological Chemistry. 288: 18939-46. PMID 23671280 DOI: 10.1074/Jbc.M113.454470  0.345
2013 Tang J, Agrawal T, Cheng Q, Qu L, Brewer MD, Chen J, Yang X. Phosphorylation of Daxx by ATM contributes to DNA damage-induced p53 activation. Plos One. 8: e55813. PMID 23405218 DOI: 10.1371/Journal.Pone.0055813  0.312
2013 Jiang P, Du W, Mancuso A, Wellen KE, Yang X. Reciprocal regulation of p53 and malic enzymes modulates metabolism and senescence. Nature. 493: 689-93. PMID 23334421 DOI: 10.1038/Nature11776  0.329
2012 Yang W, Yang X, David G, Dorsey JF. Dissecting the complex regulation of Mad4 in glioblastoma multiforme cells. Cancer Biology & Therapy. 13: 1339-48. PMID 22895069 DOI: 10.4161/Cbt.21814  0.347
2012 Bellail AC, Olson JJ, Yang X, Chen ZJ, Hao C. A20 ubiquitin ligase-mediated polyubiquitination of RIP1 inhibits caspase-8 cleavage and TRAIL-induced apoptosis in glioblastoma. Cancer Discovery. 2: 140-55. PMID 22585859 DOI: 10.1158/2159-8290.Cd-11-0172  0.455
2012 Bellail AC, Olson JJ, Yang X, Chen ZJ, Hao C. Abstract LB-72: A20 ubiquitin ligase-mediated RIP1 polyubiquitin chains inhibits TRAIL-induced apoptosis in glioblastoma Cancer Research. 72. DOI: 10.1158/1538-7445.Am2012-Lb-72  0.433
2011 Yu JW, Jeffrey PD, Ha JY, Yang X, Shi Y. Crystal structure of the mucosa-associated lymphoid tissue lymphoma translocation 1 (MALT1) paracaspase region. Proceedings of the National Academy of Sciences of the United States of America. 108: 21004-9. PMID 22158899 DOI: 10.1073/Pnas.1111708108  0.361
2011 Mei Y, Hahn AA, Hu S, Yang X. The USP19 deubiquitinase regulates the stability of c-IAP1 and c-IAP2. The Journal of Biological Chemistry. 286: 35380-7. PMID 21849505 DOI: 10.1074/Jbc.M111.282020  0.395
2011 Li N, Jiang P, Du W, Wu Z, Li C, Qiao M, Yang X, Wu M. Siva1 suppresses epithelial-mesenchymal transition and metastasis of tumor cells by inhibiting stathmin and stabilizing microtubules. Proceedings of the National Academy of Sciences of the United States of America. 108: 12851-6. PMID 21768358 DOI: 10.1073/Pnas.1017372108  0.331
2011 Chu Y, Yang X. SUMO E3 ligase activity of TRIM proteins. Oncogene. 30: 1108-1116. PMID 20972456 DOI: 10.1038/Onc.2010.462  0.352
2010 Mei Y, Stonestrom A, Hou YM, Yang X. Apoptotic regulation and tRNA. Protein & Cell. 1: 795-801. PMID 21113408 DOI: 10.1007/S13238-010-0107-X  0.401
2010 Mei Y, Yong J, Stonestrom A, Yang X. tRNA and cytochrome c in cell death and beyond. Cell Cycle (Georgetown, Tex.). 9: 2936-9. PMID 20676046 DOI: 10.4161/Cc.9.15.12316  0.38
2010 Mei Y, Yong J, Liu H, Shi Y, Meinkoth J, Dreyfuss G, Yang X. tRNA binds to cytochrome c and inhibits caspase activation. Molecular Cell. 37: 668-78. PMID 20227371 DOI: 10.1016/J.Molcel.2010.01.023  0.435
2010 Tang J, Qu L, Pang M, Yang X. Daxx is reciprocally regulated by Mdm2 and Hausp. Biochemical and Biophysical Research Communications. 393: 542-5. PMID 20153724 DOI: 10.1016/J.Bbrc.2010.02.051  0.405
2009 Du W, Jiang P, Li N, Mei Y, Wang X, Wen L, Yang X, Wu M. Suppression of p53 activity by Siva1 Cell Death & Differentiation. 16: 1493-1504. PMID 19590512 DOI: 10.1038/Cdd.2009.89  0.346
2008 Zarnegar BJ, Wang Y, Mahoney DJ, Dempsey PW, Cheung HH, He J, Shiba T, Yang X, Yeh WC, Mak TW, Korneluk RG, Cheng G. Noncanonical NF-kappaB activation requires coordinated assembly of a regulatory complex of the adaptors cIAP1, cIAP2, TRAF2 and TRAF3 and the kinase NIK. Nature Immunology. 9: 1371-8. PMID 18997794 DOI: 10.1038/Ni.1676  0.381
2008 Kawadler H, Gantz MA, Riley JL, Yang X. The paracaspase MALT1 controls caspase-8 activation during lymphocyte proliferation. Molecular Cell. 31: 415-21. PMID 18691973 DOI: 10.1016/J.Molcel.2008.06.008  0.465
2008 Park SM, Hu S, Lee TH, Yang X. Ubiquitination mediated by inhibitor of apoptosis proteins. Methods in Enzymology. 446: 225-35. PMID 18603125 DOI: 10.1016/S0076-6879(08)01613-3  0.378
2008 Sun H, Gong S, Carmody RJ, Hilliard A, Li L, Sun J, Kong L, Xu L, Hilliard B, Hu S, Shen H, Yang X, Chen YH. TIPE2, a Negative Regulator of Innate and Adaptive Immunity that Maintains Immune Homeostasis Cell. 133: 415-426. PMID 18455983 DOI: 10.1016/J.Cell.2008.03.026  0.403
2006 Kawadler H, Yang X. Lys63-linked polyubiquitin chains: linking more than just ubiquitin. Cancer Biology & Therapy. 5: 1273-4. PMID 16969079 DOI: 10.4161/Cbt.5.10.3289  0.328
2006 Tang J, Qu LK, Zhang J, Wang W, Michaelson JS, Degenhardt YY, El-Deiry WS, Yang X. Critical role for Daxx in regulating Mdm2. Nature Cell Biology. 8: 855-62. PMID 16845383 DOI: 10.1038/Ncb1442  0.412
2006 Murga Penas EM, Kawadler H, Siebert R, Frank M, Ye H, Hinz K, Becher C, Hummel M, Barth TF, Bokemeyer C, Stein H, Trümper L, Möller P, Marynen P, Du MQ, ... Yang X, et al. A novel fusion of the MALT1 gene and the microtubule-associated protein 4 (MAP4) gene occurs in diffuse large B-cell lymphoma. Genes, Chromosomes & Cancer. 45: 863-73. PMID 16804917 DOI: 10.1002/Gcc.20350  0.358
2006 Hu S, Alcivar A, Qu L, Tang J, Yang X. CIAP2 inhibits anigen receptor signaling by targeting Bcl10 for degredation. Cell Cycle (Georgetown, Tex.). 5: 1438-42. PMID 16775419 DOI: 10.4161/Cc.5.13.2866  0.721
2006 Hu S, Du MQ, Park SM, Alcivar A, Qu L, Gupta S, Tang J, Baens M, Ye H, Lee TH, Marynen P, Riley JL, Yang X. cIAP2 is a ubiquitin protein ligase for BCL10 and is dysregulated in mucosa-associated lymphoid tissue lymphomas. The Journal of Clinical Investigation. 116: 174-81. PMID 16395405 DOI: 10.1172/Jci25641  0.718
2005 Tang J, Kawadler H, Yang X. Lymphocyte life and death: the caspase-8 connection. Cancer Biology & Therapy. 4: 700-2. PMID 16082181 DOI: 10.4161/Cbt.4.7.1910  0.454
2005 Tang J, Xie W, Yang X. Association of caspase-2 with the promyelocytic leukemia protein nuclear bodies. Cancer Biology & Therapy. 4: 645-9. PMID 15917662 DOI: 10.4161/Cbt.4.6.1729  0.459
2005 Tang J, Chang HY, Yang X. The death domain-associated protein modulates activity of the transcription co-factor Skip/NcoA62. Febs Letters. 579: 2883-90. PMID 15878163 DOI: 10.1016/J.Febslet.2005.04.029  0.414
2005 Liu H, Chang DW, Yang X. Interdimer processing and linearity of procaspase-3 activation. A unifying mechanism for the activation of initiator and effector caspases. The Journal of Biological Chemistry. 280: 11578-82. PMID 15664982 DOI: 10.1074/Jbc.M414385200  0.439
2004 Tang J, Wu S, Liu H, Stratt R, Barak OG, Shiekhattar R, Picketts DJ, Yang X. A novel transcription regulatory complex containing death domain-associated protein and the ATR-X syndrome protein. The Journal of Biological Chemistry. 279: 20369-77. PMID 14990586 DOI: 10.1074/Jbc.M401321200  0.407
2003 Chang DW, Xing Z, Capacio VL, Peter ME, Yang X. Interdimer processing mechanism of procaspase-8 activation. The Embo Journal. 22: 4132-42. PMID 12912912 DOI: 10.1093/Emboj/Cdg414  0.417
2003 Chang DW, Ditsworth D, Liu H, Srinivasula SM, Alnemri ES, Yang X. Oligomerization is a general mechanism for the activation of apoptosis initiator and inflammatory procaspases. The Journal of Biological Chemistry. 278: 16466-9. PMID 12637514 DOI: 10.1074/Jbc.C300089200  0.464
2003 Chang DW, Yang X. Activation of procaspases by FK506 binding protein-mediated oligomerization. Science's Stke : Signal Transduction Knowledge Environment. 2003: PL1. PMID 12554853 DOI: 10.1126/Stke.2003.167.Pl1  0.488
2003 Alcivar A, Hu S, Tang J, Yang X. DEDD and DEDD2 associate with caspase-8/10 and signal cell death. Oncogene. 22: 291-7. PMID 12527898 DOI: 10.1038/Sj.Onc.1206099  0.719
2003 Hu S, Yang X. Cellular inhibitor of apoptosis 1 and 2 are ubiquitin ligases for the apoptosis inducer Smac/DIABLO. The Journal of Biological Chemistry. 278: 10055-60. PMID 12525502 DOI: 10.1074/Jbc.M207197200  0.487
2002 Yang X. The FLIP side of cancer cell death. Cancer Biology & Therapy. 1: 407-8. PMID 12432256 DOI: 10.4161/Cbt.1.4.16  0.324
2002 Chang DW, Xing Z, Pan Y, Algeciras-Schimnich A, Barnhart BC, Yaish-Ohad S, Peter ME, Yang X. c-FLIP(L) is a dual function regulator for caspase-8 activation and CD95-mediated apoptosis. The Embo Journal. 21: 3704-14. PMID 12110583 DOI: 10.1093/Emboj/Cdf356  0.451
2001 Chang HY, Yang X. Proteases for cell suicide: functions and regulation of caspases. Microbiology and Molecular Biology Reviews : Mmbr. 64: 821-46. PMID 11104820 DOI: 10.1128/Mmbr.64.4.821-846.2000  0.475
2000 Hu S, Yang X. dFADD, a novel death domain-containing adapter protein for the Drosophila caspase DREDD. Journal of Biological Chemistry. 275: 30761-30764. PMID 10934188 DOI: 10.1074/Jbc.C000341200  0.451
1999 Chang HY, Yang X, Baltimore D. Dissecting Fas signaling with an altered-specificity death-domain mutant: requirement of FADD binding for apoptosis but not Jun N-terminal kinase activation. Proceedings of the National Academy of Sciences of the United States of America. 96: 1252-6. PMID 9990010 DOI: 10.1073/Pnas.96.4.1252  0.445
1998 Chang HY, Nishitoh H, Yang X, Ichijo H, Baltimore D. Activation of apoptosis signal-regulating kinase 1 (ASK1) by the adapter protein Daxx. Science (New York, N.Y.). 281: 1860-3. PMID 9743501 DOI: 10.1126/Science.281.5384.1860  0.422
1998 Yang X, Chang HY, Baltimore D. Essential role of CED-4 oligomerization in CED-3 activation and apoptosis. Science (New York, N.Y.). 281: 1355-7. PMID 9721101 DOI: 10.1126/Science.281.5381.1355  0.49
1998 Yang X, Chang HY, Baltimore D. Autoproteolytic activation of pro-caspases by oligomerization. Molecular Cell. 1: 319-25. PMID 9659928 DOI: 10.1016/S1097-2765(00)80032-5  0.457
1997 Yang X, Khosravi-Far R, Chang HY, Baltimore D. Daxx, a novel Fas-binding protein that activates JNK and apoptosis. Cell. 89: 1067-76. PMID 9215629 DOI: 10.1016/S0092-8674(00)80294-9  0.484
1996 Lesage P, Yang X, Carlson M. Yeast SNF1 protein kinase interacts with SIP4, a C6 zinc cluster transcriptional activator: a new role for SNF1 in the glucose response. Molecular and Cellular Biology. 16: 1921-8. PMID 8628258 DOI: 10.1128/Mcb.16.5.1921  0.352
1994 Lesage P, Yang X, Carlson M. Analysis of the SIP3 protein identified in a two-hybrid screen for interaction with the SNF1 protein kinase. Nucleic Acids Research. 22: 597-603. PMID 8127709 DOI: 10.1093/Nar/22.4.597  0.37
1994 Yang X, Jiang R, Carlson M. A family of proteins containing a conserved domain that mediates interaction with the yeast SNF1 protein kinase complex. The Embo Journal. 13: 5878-5886. DOI: 10.1002/J.1460-2075.1994.Tb06933.X  0.383
1992 Laurent BC, Yang X, Carlson M. An essential Saccharomyces cerevisiae gene homologous to SNF2 encodes a helicase-related protein in a new family. Molecular and Cellular Biology. 12: 1893-902. PMID 1549132 DOI: 10.1128/mcb.12.4.1893-1902.1992  0.331
1992 Yang X, Hubbard EJ, Carlson M. A protein kinase substrate identified by the two-hybrid system. Science (New York, N.Y.). 257: 680-2. PMID 1496382 DOI: 10.1126/Science.1496382  0.324
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