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Shingo Kajimura - Publications

Affiliations: 
Biochemistry and Molecular Biology University of California, San Francisco, San Francisco, CA 
Area:
Molecular Biology, Biochemistry, Cell Biology
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Year Citation  Score
2023 Yook JS, Taxin ZH, Yuan B, Oikawa S, Auger C, Mutlu B, Puigserver P, Hui S, Kajimura S. The SLC25A47 locus controls gluconeogenesis and energy expenditure. Proceedings of the National Academy of Sciences of the United States of America. 120: e2216810120. PMID 36812201 DOI: 10.1073/pnas.2216810120  0.573
2022 Yoshizawa T, Sato Y, Sobuz SU, Mizumoto T, Tsuyama T, Karim MF, Miyata K, Tasaki M, Yamazaki M, Kariba Y, Araki N, Araki E, Kajimura S, Oike Y, Braun T, et al. SIRT7 suppresses energy expenditure and thermogenesis by regulating brown adipose tissue functions in mice. Nature Communications. 13: 7439. PMID 36509749 DOI: 10.1038/s41467-022-35219-z  0.4
2022 Auger C, Kajimura S. Adipose Tissue Remodeling in Pathophysiology. Annual Review of Pathology. PMID 36070562 DOI: 10.1146/annurev-pathol-042220-023633  0.368
2022 Wang Q, Li H, Tajima K, Verkerke ARP, Taxin ZH, Hou Z, Cole JB, Li F, Wong J, Abe I, Pradhan RN, Yamamuro T, Yoneshiro T, Hirschhorn JN, Kajimura S. Post-translational control of beige fat biogenesis by PRDM16 stabilization. Nature. PMID 35978186 DOI: 10.1038/s41586-022-05067-4  0.442
2022 Yook JS, Kajimura S. Is thermogenesis really needed for brown adipose tissue-mediated metabolic benefit? The Journal of Clinical Investigation. 132. PMID 35499086 DOI: 10.1172/JCI159296  0.4
2021 Yoshida N, Yamashita T, Osone T, Hosooka T, Shinohara M, Kitahama S, Sasaki K, Sasaki D, Yoneshiro T, Suzuki T, Emoto T, Saito Y, Ozawa G, Hirota Y, Kitaura Y, ... ... Kajimura S, et al. spp. promotes branched-chain amino acid catabolism in brown fat and inhibits obesity. Iscience. 24: 103342. PMID 34805797 DOI: 10.1016/j.isci.2021.103342  0.367
2021 Wang B, Tsakiridis EE, Zhang S, Llanos A, Desjardins EM, Yabut JM, Green AE, Day EA, Smith BK, Lally JSV, Wu J, Raphenya AR, Srinivasan KA, McArthur AG, Kajimura S, et al. The pesticide chlorpyrifos promotes obesity by inhibiting diet-induced thermogenesis in brown adipose tissue. Nature Communications. 12: 5163. PMID 34453052 DOI: 10.1038/s41467-021-25384-y  0.447
2021 Kajimura S. Bioenergetics matter to metabolic health-from a fat progenitor view. Cell Stem Cell. 28: 589-591. PMID 33798417 DOI: 10.1016/j.stem.2021.03.008  0.323
2021 Cohen P, Kajimura S. The cellular and functional complexity of thermogenic fat. Nature Reviews. Molecular Cell Biology. PMID 33758402 DOI: 10.1038/s41580-021-00350-0  0.549
2021 Kajimura S. The epigenetic regulation of adipose tissue plasticity. Proceedings of the National Academy of Sciences of the United States of America. 118. PMID 33741735 DOI: 10.1073/pnas.2102944118  0.303
2021 Conn CS, Yang H, Tom HJ, Ikeda K, Oses-Prieto JA, Vu H, Oguri Y, Nair S, Gill RM, Kajimura S, DeBerardinis RJ, Burlingame AL, Ruggero D. The major cap-binding protein eIF4E regulates lipid homeostasis and diet-induced obesity. Nature Metabolism. 3: 244-257. PMID 33619378 DOI: 10.1038/s42255-021-00349-z  0.379
2020 Sponton CH, Hosono T, Taura J, Jedrychowski MP, Yoneshiro T, Wang Q, Takahashi M, Matsui Y, Ikeda K, Oguri Y, Tajima K, Shinoda K, Pradhan RN, Chen Y, Brown Z, ... ... Kajimura S, et al. The regulation of glucose and lipid homeostasis via PLTP as a mediator of BAT-liver communication. Embo Reports. e49828. PMID 32672883 DOI: 10.15252/Embr.201949828  0.395
2020 Verkerke ARP, Kajimura S. A new way to ignite thermogenesis in human adipose tissue. Nature Reviews. Endocrinology. PMID 32641836 DOI: 10.1038/S41574-020-0390-4  0.457
2020 Oguri Y, Shinoda K, Kim H, Alba DL, Bolus WR, Wang Q, Brown Z, Pradhan RN, Tajima K, Yoneshiro T, Ikeda K, Chen Y, Cheang RT, Tsujino K, Kim CR, ... ... Kajimura S, et al. CD81 Controls Beige Fat Progenitor Cell Growth and Energy Balance via FAK Signaling. Cell. PMID 32615086 DOI: 10.1016/J.Cell.2020.06.021  0.595
2020 Wang Z, Liu X, Liu M, Jiang K, Kajimura S, Kim H, Feeley BT. Beta-3 Adrenergic Receptor Agonist Treats Rotator Cuff Fatty Infiltration by Activating Brown/beige Fat in Mice. Journal of Shoulder and Elbow Surgery. PMID 32599287 DOI: 10.1016/J.Jse.2020.06.006  0.387
2020 Jun H, Ma Y, Chen Y, Gong J, Liu S, Wang J, Knights AJ, Qiao X, Emont MP, Xu XZS, Kajimura S, Wu J. Adrenergic-Independent Signaling via CHRNA2 Regulates Beige Fat Activation. Developmental Cell. PMID 32533922 DOI: 10.1016/J.Devcel.2020.05.017  0.518
2020 Kajimura S, Spiegelman BM. Confounding issues in the "humanized" BAT of mice. Nature Metabolism. 2: 303-304. PMID 32405619 DOI: 10.1038/s42255-020-0192-y  0.419
2020 Wang Z, Liu X, Jiang K, Kim H, Kajimura S, Feeley BT. Intramuscular Brown Fat Activation Decreases Muscle Atrophy and Fatty Infiltration and Improves Gait After Delayed Rotator Cuff Repair in Mice. The American Journal of Sports Medicine. 363546520910421. PMID 32282238 DOI: 10.1177/0363546520910421  0.359
2020 Tajima K, Ikeda K, Tanabe Y, Thomson EA, Yoneshiro T, Oguri Y, Ferro MD, Poon ASY, Kajimura S. Wireless optogenetics protects against obesity via stimulation of non-canonical fat thermogenesis. Nature Communications. 11: 1730. PMID 32265443 DOI: 10.1038/S41467-020-15589-Y  0.482
2019 Tajima K, Ikeda K, Chang HY, Chang CH, Yoneshiro T, Oguri Y, Jun H, Wu J, Ishihama Y, Kajimura S. Mitochondrial lipoylation integrates age-associated decline in brown fat thermogenesis. Nature Metabolism. 1: 886-898. PMID 32313871 DOI: 10.1038/s42255-019-0106-z  0.399
2019 Chouchani ET, Kajimura S. Metabolic adaptation and maladaptation in adipose tissue. Nature Metabolism. 1: 189-200. PMID 31903450 DOI: 10.1038/s42255-018-0021-8  0.72
2019 Oguri Y, Kajimura S. Cellular heterogeneity in brown adipose tissue. The Journal of Clinical Investigation. PMID 31763995 DOI: 10.1172/Jci133786  0.518
2019 Wang Q, Kajimura S. Naa10P puts a brake on PGC1α and fat browning. Nature Structural & Molecular Biology. PMID 31527714 DOI: 10.1038/S41594-019-0310-2  0.419
2019 Yoneshiro T, Wang Q, Tajima K, Matsushita M, Maki H, Igarashi K, Dai Z, White PJ, McGarrah RW, Ilkayeva OR, Deleye Y, Oguri Y, Kuroda M, Ikeda K, Li H, ... ... Kajimura S, et al. BCAA catabolism in brown fat controls energy homeostasis through SLC25A44. Nature. PMID 31435015 DOI: 10.1038/S41586-019-1503-X  0.522
2019 Dumesic PA, Egan DF, Gut P, Tran MT, Parisi A, Chatterjee N, Jedrychowski M, Paschini M, Kazak L, Wilensky SE, Dou F, Bogoslavski D, Cartier JA, Perrimon N, Kajimura S, et al. An Evolutionarily Conserved uORF Regulates PGC1α and Oxidative Metabolism in Mice, Flies, and Bluefin Tuna. Cell Metabolism. PMID 31105043 DOI: 10.1016/J.Cmet.2019.04.013  0.728
2019 Kajimura S. The Color of Fat: brown, white, beige, and more Obesity Research & Clinical Practice. 13: 262. DOI: 10.1016/J.Orcp.2018.11.078  0.362
2018 Chen Y, Ikeda K, Yoneshiro T, Scaramozza A, Tajima K, Wang Q, Kim K, Shinoda K, Sponton CH, Brown Z, Brack A, Kajimura S. Thermal stress induces glycolytic beige fat formation via a myogenic state. Nature. PMID 30568302 DOI: 10.1038/S41586-018-0801-Z  0.466
2018 Mills EL, Pierce KA, Jedrychowski MP, Garrity R, Winther S, Vidoni S, Yoneshiro T, Spinelli JB, Lu GZ, Kazak L, Banks AS, Haigis MC, Kajimura S, Murphy MP, Gygi SP, et al. Accumulation of succinate controls activation of adipose tissue thermogenesis. Nature. PMID 30022159 DOI: 10.1038/S41586-018-0353-2  0.807
2018 Sponton CH, Kajimura S. AAV-mediated gene therapy as a strategy to fight obesity and metabolic diseases. Embo Molecular Medicine. PMID 30021799 DOI: 10.15252/Emmm.201809431  0.417
2018 Sponton CH, Kajimura S. Multifaceted roles of beige fat in energy homeostasis beyond UCP1. Endocrinology. PMID 29757365 DOI: 10.1210/En.2018-00371  0.536
2018 Lu X, Altshuler-Keylin S, Wang Q, Chen Y, Henrique Sponton C, Ikeda K, Maretich P, Yoneshiro T, Kajimura S. Mitophagy controls beige adipocyte maintenance through a Parkin-dependent and UCP1-independent mechanism. Science Signaling. 11. PMID 29692364 DOI: 10.1126/Scisignal.Aap8526  0.426
2018 Abe Y, Fujiwara Y, Takahashi H, Matsumura Y, Sawada T, Jiang S, Nakaki R, Uchida A, Nagao N, Naito M, Kajimura S, Kimura H, Osborne TF, Aburatani H, Kodama T, et al. Histone demethylase JMJD1A coordinates acute and chronic adaptation to cold stress via thermogenic phospho-switch. Nature Communications. 9: 1566. PMID 29674659 DOI: 10.1038/S41467-018-03868-8  0.358
2018 Tharp KM, Kang MS, Timblin GA, Dempersmier J, Dempsey GE, Zushin PH, Benavides J, Choi C, Li CX, Jha AK, Kajimura S, Healy KE, Sul HS, Saijo K, Kumar S, et al. Actomyosin-Mediated Tension Orchestrates Uncoupled Respiration in Adipose Tissues. Cell Metabolism. 27: 602-615.e4. PMID 29514068 DOI: 10.1016/J.Cmet.2018.02.005  0.492
2018 Ikeda K, Maretich P, Kajimura S. The Common and Distinct Features of Brown and Beige Adipocytes. Trends in Endocrinology and Metabolism: Tem. PMID 29366777 DOI: 10.1016/J.Tem.2018.01.001  0.505
2018 Hasegawa Y, Ikeda K, Chen Y, Alba DL, Stifler D, Shinoda K, Hosono T, Maretich P, Yang Y, Ishigaki Y, Chi J, Cohen P, Koliwad SK, Kajimura S. Repression of Adipose Tissue Fibrosis through a PRDM16-GTF2IRD1 Complex Improves Systemic Glucose Homeostasis. Cell Metabolism. 27: 180-194.e6. PMID 29320702 DOI: 10.1016/J.Cmet.2017.12.005  0.618
2017 Ikeda K, Kang Q, Yoneshiro T, Camporez JP, Maki H, Homma M, Shinoda K, Chen Y, Lu X, Maretich P, Tajima K, Ajuwon KM, Soga T, Kajimura S. UCP1-independent signaling involving SERCA2b-mediated calcium cycling regulates beige fat thermogenesis and systemic glucose homeostasis. Nature Medicine. PMID 29131158 DOI: 10.1038/Nm.4429  0.451
2017 Fukunaka A, Fukada T, Bhin J, Suzuki L, Tsuzuki T, Takamine Y, Bin BH, Yoshihara T, Ichinoseki-Sekine N, Naito H, Miyatsuka T, Takamiya S, Sasaki T, Inagaki T, Kitamura T, ... Kajimura S, et al. Zinc transporter ZIP13 suppresses beige adipocyte biogenesis and energy expenditure by regulating C/EBP-β expression. Plos Genetics. 13: e1006950. PMID 28854265 DOI: 10.1371/Journal.Pgen.1006950  0.478
2017 Sponton CH, Kajimura S. Burning Fat and Building Bone by FSH Blockade. Cell Metabolism. 26: 285-287. PMID 28768167 DOI: 10.1016/J.Cmet.2017.07.018  0.408
2017 Choi SE, Kwon S, Seok S, Xiao Z, Lee KW, Kang Y, Li X, Shinoda K, Kajimura S, Kemper B, Kemper JK. Obesity-linked phosphorylation of SIRT1 by CK2 inhibits its nuclear localization and promotes fatty liver. Molecular and Cellular Biology. PMID 28533219 DOI: 10.1128/Mcb.00006-17  0.445
2017 Sonne SB, Yadav R, Yin G, Dalgaard MD, Myrmel LS, Gupta R, Wang J, Madsen L, Kajimura S, Kristiansen K. Obesity is associated with depot-specific alterations in adipocyte DNA methylation and gene expression. Adipocyte. 1-10. PMID 28481699 DOI: 10.1080/21623945.2017.1320002  0.336
2017 Bertholet AM, Kazak L, Chouchani ET, Bogaczyńska MG, Paranjpe I, Wainwright GL, Bétourné A, Kajimura S, Spiegelman BM, Kirichok Y. Mitochondrial Patch Clamp of Beige Adipocytes Reveals UCP1-Positive and UCP1-Negative Cells Both Exhibiting Futile Creatine Cycling. Cell Metabolism. 25: 811-822.e4. PMID 28380374 DOI: 10.1016/J.Bbabio.2018.09.358  0.764
2017 Altshuler-Keylin S, Kajimura S. Mitochondrial homeostasis in adipose tissue remodeling. Science Signaling. 10. PMID 28246203 DOI: 10.1126/Scisignal.Aai9248  0.485
2017 Giordano A, Perugini J, Kristensen DM, Sartini L, Frontini A, Kajimura S, Kristiansen K, Cinti S. Mammary Alveolar Epithelial Cells Convert to Brown Adipocytes in Post-lactating Mice. Journal of Cellular Physiology. PMID 28191637 DOI: 10.1002/Jcp.25858  0.394
2017 Kajimura S. Adipose tissue in 2016: Advances in the understanding of adipose tissue biology. Nature Reviews. Endocrinology. PMID 28051117 DOI: 10.1038/Nrendo.2016.211  0.478
2016 Kajimura S. PDGFA Makes Thin Skin Thicker: Molecular Regulation of Adipose Progenitor Maintenance. Cell Stem Cell. 19: 675-676. PMID 27912085 DOI: 10.1016/J.Stem.2016.11.010  0.411
2016 Koh EH, Chen Y, Bader DA, Hamilton MP, He B, York B, Kajimura S, McGuire SE, Hartig SM. Mitochondrial activity in human white adipocytes is regulated by the Ubiquitin Carrier Protein 9/microRNA-30a axis. The Journal of Biological Chemistry. PMID 27758866 DOI: 10.1074/Jbc.M116.749408  0.445
2016 Altshuler-Keylin S, Shinoda K, Hasegawa Y, Ikeda K, Hong H, Kang Q, Yang Y, Perera RM, Debnath J, Kajimura S. Beige Adipocyte Maintenance Is Regulated by Autophagy-Induced Mitochondrial Clearance. Cell Metabolism. PMID 27568548 DOI: 10.1016/J.Cmet.2016.08.002  0.489
2016 Inagaki T, Sakai J, Kajimura S. Transcriptional and epigenetic control of brown and beige adipose cell fate and function. Nature Reviews. Molecular Cell Biology. PMID 27251423 DOI: 10.1038/Nrm.2016.62  0.505
2016 Chondronikola M, Volpi E, Børsheim E, Porter C, Saraf MK, Annamalai P, Yfanti C, Chao T, Wong D, Shinoda K, Labbė SM, Hurren NM, Cesani F, Kajimura S, Sidossis LS. Brown Adipose Tissue Activation Is Linked to Distinct Systemic Effects on Lipid Metabolism in Humans. Cell Metabolism. PMID 27238638 DOI: 10.1016/J.Cmet.2016.04.029  0.494
2016 Camarda R, Zhou AY, Kohnz RA, Balakrishnan S, Mahieu C, Anderton B, Eyob H, Kajimura S, Tward A, Krings G, Nomura DK, Goga A. Inhibition of fatty acid oxidation as a therapy for MYC-overexpressing triple-negative breast cancer. Nature Medicine. PMID 26950360 DOI: 10.1038/Nm.4055  0.323
2016 Ohyama K, Nogusa Y, Shinoda K, Suzuki K, Bannai M, Kajimura S. A synergistic anti-obesity effect by a combination of capsinoids and cold temperature through promoting beige adipocyte biogenesis. Diabetes. PMID 26936964 DOI: 10.2337/Db15-0662  0.483
2016 Svensson KJ, Long JZ, Jedrychowski MP, Cohen P, Lo JC, Serag S, Kir S, Shinoda K, Tartaglia JA, Rao RR, Chédotal A, Kajimura S, Gygi SP, Spiegelman BM. A Secreted Slit2 Fragment Regulates Adipose Tissue Thermogenesis and Metabolic Function. Cell Metabolism. PMID 26876562 DOI: 10.1016/J.Cmet.2016.01.008  0.814
2016 Klionsky DJ, Abdelmohsen K, Abe A, Abedin MJ, Abeliovich H, Acevedo Arozena A, Adachi H, Adams CM, Adams PD, Adeli K, Adhihetty PJ, Adler SG, Agam G, Agarwal R, Aghi MK, ... ... Kajimura S, et al. Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition). Autophagy. 12: 1-222. PMID 26799652 DOI: 10.1080/15548627.2015.1100356  0.44
2016 Camarda R, Zhou AY, Kohnz RA, Balakrishnan S, Mahieu C, Anderton B, Eyob H, Kajimura S, Tward A, Krings G, Nomura DK, Goga A. Abstract 2673: Inhibition of fatty-acid oxidation as a therapy for MYC-overexpressing triple-negative breast cancer Cancer Research. 76: 2673-2673. DOI: 10.1158/1538-7445.Am2016-2673  0.312
2015 Kajimura S. Promoting brown and beige adipocyte biogenesis through the PRDM16 pathway. International Journal of Obesity Supplements. 5: S11-4. PMID 27152168 DOI: 10.1038/ijosup.2015.4  0.376
2015 Kajimura S. Engineering Fat Cell Fate to Fight Obesity and Metabolic Diseases. The Keio Journal of Medicine. 64: 65. PMID 26727580 DOI: 10.1016/J.Orcp.2014.10.096  0.45
2015 Shinoda K, Ohyama K, Hasegawa Y, Chang HY, Ogura M, Sato A, Hong H, Hosono T, Sharp LZ, Scheel DW, Graham M, Ishihama Y, Kajimura S. Phosphoproteomics Identifies CK2 as a Negative Regulator of Beige Adipocyte Thermogenesis and Energy Expenditure. Cell Metabolism. PMID 26525534 DOI: 10.1016/J.Cmet.2015.09.029  0.473
2015 Kazak L, Chouchani ET, Jedrychowski MP, Erickson BK, Shinoda K, Cohen P, Vetrivelan R, Lu GZ, Laznik-Bogoslavski D, Hasenfuss SC, Kajimura S, Gygi SP, Spiegelman BM. A Creatine-Driven Substrate Cycle Enhances Energy Expenditure and Thermogenesis in Beige Fat. Cell. 163: 643-55. PMID 26496606 DOI: 10.1016/J.Cell.2015.09.035  0.818
2015 Güller I, McNaughton S, Crowley T, Gilsanz V, Kajimura S, Watt M, Russell AP. Comparative analysis of microRNA expression in mouse and human brown adipose tissue. Bmc Genomics. 16: 820. PMID 26482036 DOI: 10.1186/S12864-015-2045-8  0.446
2015 Kajimura S, Spiegelman BM, Seale P. Brown and Beige Fat: Physiological Roles beyond Heat Generation. Cell Metabolism. 22: 546-59. PMID 26445512 DOI: 10.1016/J.Cmet.2015.09.007  0.755
2015 Abe Y, Rozqie R, Matsumura Y, Kawamura T, Nakaki R, Tsurutani Y, Tanimura-Inagaki K, Shiono A, Magoori K, Nakamura K, Ogi S, Kajimura S, Kimura H, Tanaka T, Fukami K, et al. JMJD1A is a signal-sensing scaffold that regulates acute chromatin dynamics via SWI/SNF association for thermogenesis. Nature Communications. 6: 7052. PMID 25948511 DOI: 10.1038/Ncomms8052  0.34
2015 Oh CM, Namkung J, Go Y, Shong KE, Kim K, Kim H, Park BY, Lee HW, Jeon YH, Song J, Shong M, Yadav VK, Karsenty G, Kajimura S, Lee IK, et al. Regulation of systemic energy homeostasis by serotonin in adipose tissues. Nature Communications. 6: 6794. PMID 25864946 DOI: 10.1038/Ncomms7794  0.399
2015 Shinoda K, Luijten IH, Hasegawa Y, Hong H, Sonne SB, Kim M, Xue R, Chondronikola M, Cypess AM, Tseng YH, Nedergaard J, Sidossis LS, Kajimura S. Genetic and functional characterization of clonally derived adult human brown adipocytes. Nature Medicine. 21: 389-94. PMID 25774848 DOI: 10.1038/Nm.3819  0.435
2015 Sidossis L, Kajimura S. Brown and beige fat in humans: thermogenic adipocytes that control energy and glucose homeostasis. The Journal of Clinical Investigation. 125: 478-86. PMID 25642708 DOI: 10.1172/Jci78362  0.514
2015 Ohyama K, Nogusa Y, Suzuki K, Shinoda K, Kajimura S, Bannai M. A combination of exercise and capsinoid supplementation additively suppresses diet-induced obesity by increasing energy expenditure in mice. American Journal of Physiology. Endocrinology and Metabolism. 308: E315-23. PMID 25516550 DOI: 10.1152/Ajpendo.00354.2014  0.403
2014 Galmozzi A, Sonne SB, Altshuler-Keylin S, Hasegawa Y, Shinoda K, Luijten IH, Chang JW, Sharp LZ, Cravatt BF, Saez E, Kajimura S. ThermoMouse: an in vivo model to identify modulators of UCP1 expression in brown adipose tissue. Cell Reports. 9: 1584-93. PMID 25466254 DOI: 10.1016/J.Celrep.2014.10.066  0.728
2014 Gridley T, Kajimura S. Lightening up a notch: Notch regulation of energy metabolism. Nature Medicine. 20: 811-2. PMID 25100522 DOI: 10.1038/Nm.3650  0.411
2014 Cohen P, Levy JD, Zhang Y, Frontini A, Kolodin DP, Svensson KJ, Lo JC, Zeng X, Ye L, Khandekar MJ, Wu J, Gunawardana SC, Banks AS, Camporez JP, Jurczak MJ, ... Kajimura S, et al. Ablation of PRDM16 and beige adipose causes metabolic dysfunction and a subcutaneous to visceral fat switch. Cell. 156: 304-16. PMID 24439384 DOI: 10.1016/J.Cell.2013.12.021  0.813
2014 Kajimura S, Saito M. A new era in brown adipose tissue biology: molecular control of brown fat development and energy homeostasis. Annual Review of Physiology. 76: 225-49. PMID 24188710 DOI: 10.1146/Annurev-Physiol-021113-170252  0.504
2013 Ohno H, Shinoda K, Ohyama K, Sharp LZ, Kajimura S. EHMT1 controls brown adipose cell fate and thermogenesis through the PRDM16 complex. Nature. 504: 163-7. PMID 24196706 DOI: 10.1038/Nature12652  0.527
2013 Aune UL, Ruiz L, Kajimura S. Isolation and differentiation of stromal vascular cells to beige/brite cells. Journal of Visualized Experiments : Jove. PMID 23568137 DOI: 10.3791/50191  0.487
2013 Gilsanz V, Hu HH, Kajimura S. Relevance of brown adipose tissue in infancy and adolescence. Pediatric Research. 73: 3-9. PMID 23090604 DOI: 10.1038/Pr.2012.141  0.367
2012 Kang S, Akerblad P, Kiviranta R, Gupta RK, Kajimura S, Griffin MJ, Min J, Baron R, Rosen ED. Regulation of early adipose commitment by Zfp521. Plos Biology. 10: e1001433. PMID 23209378 DOI: 10.1371/Journal.Pbio.1001433  0.764
2012 Sharp LZ, Shinoda K, Ohno H, Scheel DW, Tomoda E, Ruiz L, Hu H, Wang L, Pavlova Z, Gilsanz V, Kajimura S. Human BAT possesses molecular signatures that resemble beige/brite cells. Plos One. 7: e49452. PMID 23166672 DOI: 10.1371/Journal.Pone.0049452  0.496
2012 Koncarevic A, Kajimura S, Cornwall-Brady M, Andreucci A, Pullen A, Sako D, Kumar R, Grinberg AV, Liharska K, Ucran JA, Howard E, Spiegelman BM, Seehra J, Lachey J. A novel therapeutic approach to treating obesity through modulation of TGFβ signaling. Endocrinology. 153: 3133-46. PMID 22549226 DOI: 10.1210/En.2012-1016  0.672
2012 Ohno H, Shinoda K, Spiegelman BM, Kajimura S. PPARγ agonists induce a white-to-brown fat conversion through stabilization of PRDM16 protein. Cell Metabolism. 15: 395-404. PMID 22405074 DOI: 10.1016/J.Cmet.2012.01.019  0.664
2012 Boström P, Wu J, Jedrychowski MP, Korde A, Ye L, Lo JC, Rasbach KA, Boström EA, Choi JH, Long JZ, Kajimura S, Zingaretti MC, Vind BF, Tu H, Cinti S, et al. A PGC1-α-dependent myokine that drives brown-fat-like development of white fat and thermogenesis. Nature. 481: 463-8. PMID 22237023 DOI: 10.1038/Nature10777  0.775
2012 Boström P, Wu J, Jedrychowski MP, Korde A, Ye L, Lo JC, Rasbach KA, Boström EA, Choi JH, Long JZ, Kajimura S, Zingaretti MC, Vind BF, Tu H, Cinti S, et al. Boström et al. reply Nature. 488: E10-E11. DOI: 10.1038/Nature11365  0.681
2011 Seale P, Conroe HM, Estall J, Kajimura S, Frontini A, Ishibashi J, Cohen P, Cinti S, Spiegelman BM. Prdm16 determines the thermogenic program of subcutaneous white adipose tissue in mice. The Journal of Clinical Investigation. 121: 96-105. PMID 21123942 DOI: 10.1172/Jci44271  0.828
2010 Choi JH, Banks AS, Estall JL, Kajimura S, Boström P, Laznik D, Ruas JL, Chalmers MJ, Kamenecka TM, Blüher M, Griffin PR, Spiegelman BM. Anti-diabetic drugs inhibit obesity-linked phosphorylation of PPARgamma by Cdk5. Nature. 466: 451-6. PMID 20651683 DOI: 10.1038/Nature09291  0.781
2010 Kajimura S, Seale P, Spiegelman BM. Transcriptional control of brown fat development. Cell Metabolism. 11: 257-62. PMID 20374957 DOI: 10.1016/J.Cmet.2010.03.005  0.699
2009 Kajimura S, Seale P, Kubota K, Lunsford E, Frangioni JV, Gygi SP, Spiegelman BM. Initiation of myoblast to brown fat switch by a PRDM16-C/EBP-beta transcriptional complex. Nature. 460: 1154-8. PMID 19641492 DOI: 10.1038/Nature08262  0.755
2009 Seale P, Kajimura S, Spiegelman BM. Transcriptional control of brown adipocyte development and physiological function--of mice and men. Genes & Development. 23: 788-97. PMID 19339685 DOI: 10.1101/Gad.1779209  0.752
2008 Cooper MP, Uldry M, Kajimura S, Arany Z, Spiegelman BM. Modulation of PGC-1 coactivator pathways in brown fat differentiation through LRP130. The Journal of Biological Chemistry. 283: 31960-7. PMID 18728005 DOI: 10.1074/Jbc.M805431200  0.65
2008 Seale P, Bjork B, Yang W, Kajimura S, Chin S, Kuang S, Scimè A, Devarakonda S, Conroe HM, Erdjument-Bromage H, Tempst P, Rudnicki MA, Beier DR, Spiegelman BM. PRDM16 controls a brown fat/skeletal muscle switch. Nature. 454: 961-7. PMID 18719582 DOI: 10.1038/Nature07182  0.753
2008 Kajimura S, Seale P, Tomaru T, Erdjument-Bromage H, Cooper MP, Ruas JL, Chin S, Tempst P, Lazar MA, Spiegelman BM. Regulation of the brown and white fat gene programs through a PRDM16/CtBP transcriptional complex. Genes & Development. 22: 1397-409. PMID 18483224 DOI: 10.1101/Gad.1666108  0.792
2007 Seale P, Kajimura S, Yang W, Chin S, Rohas LM, Uldry M, Tavernier G, Langin D, Spiegelman BM. Transcriptional control of brown fat determination by PRDM16. Cell Metabolism. 6: 38-54. PMID 17618855 DOI: 10.1016/J.Cmet.2007.06.001  0.758
2007 Kajimura S, Duan C. Insulin-like growth factor-binding protein-1: An evolutionarily conserved fine tuner of insulin-like growth factor action under catabolic and stressful conditions Journal of Fish Biology. 71: 309-325. DOI: 10.1111/J.1095-8649.2007.01606.X  0.308
2006 Kajimura S, Aida K, Duan C. Understanding hypoxia-induced gene expression in early development: in vitro and in vivo analysis of hypoxia-inducible factor 1-regulated zebra fish insulin-like growth factor binding protein 1 gene expression. Molecular and Cellular Biology. 26: 1142-55. PMID 16428465 DOI: 10.1128/Mcb.26.3.1142-1155.2006  0.35
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