Kazuma Murakami, Ph.D. - Related publications

Food Science and Biotechnology  Kyoto University, Kyōto-shi, Kyōto-fu, Japan 
Alzheimer's disease
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50 most relevant papers in past 60 days:
Year Citation  Score
2020 Gharibyan AL, Islam T, Pettersson N, Golchin SA, Lundgren J, Johansson G, Genot M, Schultz N, Wennström M, Olofsson A. Apolipoprotein E Interferes with IAPP Aggregation and Protects Pericytes from IAPP-Induced Toxicity. Biomolecules. 10. PMID 31947546 DOI: 10.3390/biom10010134   
2020 Polis B, Samson AO. Role of the metabolism of branched-chain amino acids in the development of Alzheimer's disease and other metabolic disorders. Neural Regeneration Research. 15: 1460-1470. PMID 31997805 DOI: 10.4103/1673-5374.274328   
2020 Prikhodko O, Rynearson KD, Sekhon T, Mante MM, Nguyen PD, Rissman RA, Tanzi RE, Wagner SL. The GSM BPN-15606 as a Potential Candidate for Preventative Therapy in Alzheimer's Disease. Journal of Alzheimer's Disease : Jad. PMID 31958080 DOI: 10.3233/JAD-190442   
2020 Li D, Liu C. Structural diversity of amyloid fibrils and advances in their structure determination. Biochemistry. PMID 31967790 DOI: 10.1021/acs.biochem.9b01069   
2020 Yan T, Liang J, Gao J, Wang L, Fujioka H, , Zhu X, Wang X. FAM222A encodes a protein which accumulates in plaques in Alzheimer's disease. Nature Communications. 11: 411. PMID 31964863 DOI: 10.1038/s41467-019-13962-0   
2020 McAllister BB, Lacoursiere SG, Sutherland RJ, Mohajerani MH. Intracerebral seeding of amyloid-β and tau pathology in mice: factors underlying prion-like spreading and comparisons with α-synuclein. Neuroscience and Biobehavioral Reviews. PMID 31996301 DOI: 10.1016/j.neubiorev.2020.01.026   
2020 Ohta Y, Hishikawa N, Ikegami K, Sato K, Osakada Y, Takemoto M, Yamashita T, Omote Y, Ikeuchi T, Abe K. Different clinical and neuroimaging features of Japanese dementia siblings with a new N-terminal mutation (Val225Ala) of APP gene. Journal of Clinical Neuroscience : Official Journal of the Neurosurgical Society of Australasia. PMID 31937505 DOI: 10.1016/j.jocn.2019.11.009   
2020 Weigand AJ, Bangen KJ, Thomas KR, Delano-Wood L, Gilbert PE, Brickman AM, Bondi MW, . Is tau in the absence of amyloid on the Alzheimer's continuum?: A study of discordant PET positivity. Brain Communications. 2: fcz046. PMID 32051933 DOI: 10.1093/braincomms/fcz046   
2020 Rice HC, Marcassa G, Chrysidou I, Horré K, Young-Pearse TL, Müller UC, Saito T, Saido TC, Vassar R, de Wit J, De Strooper B. Contribution of GABAergic interneurons to amyloid-β plaque pathology in an APP knock-in mouse model. Molecular Neurodegeneration. 15: 3. PMID 31915042 DOI: 10.1186/s13024-019-0356-y   
2020 Seki T, Kanagawa M, Kobayashi K, Kowa H, Yahata N, Maruyama K, Iwata N, Inoue H, Toda T. Galectin 3-binding protein suppresses amyloid-β production by modulating β-cleavage of amyloid precursor protein. The Journal of Biological Chemistry. PMID 31996371 DOI: 10.1074/jbc.RA119.008703   
2020 Iyaswamy A, Krishnamoorthi SK, Song JX, Yang CB, Kaliyamoorthy V, Zhang H, Sreenivasmurthy SG, Malampati S, Wang ZY, Zhu Z, Tong BC, Cheung KH, Lu JH, Durairajan SSK, Li M. NeuroDefend, a novel Chinese medicine, attenuates amyloid-β and tau pathology in experimental Alzheimer's disease models. Journal of Food and Drug Analysis. 28: 132-146. PMID 31883601 DOI: 10.1016/j.jfda.2019.09.004   
2020 Galla L, Redolfi N, Pozzan T, Pizzo P, Greotti E. Intracellular Calcium Dysregulation by the Alzheimer's Disease-Linked Protein Presenilin 2. International Journal of Molecular Sciences. 21. PMID 31991578 DOI: 10.3390/ijms21030770   
2020 Nandakumar A, Xing Y, Aranha RR, Faridi A, Kakinen A, Javed I, Koppel K, Pilkington EH, Purcell AW, Davis TP, Faridi P, Ding F, Ke PC. Human Plasma Protein Corona of Aβ Amyloid and Its Impact on IAPP Cross-Seeding. Biomacromolecules. PMID 31909987 DOI: 10.1021/acs.biomac.9b01650   
2020 Chintapaludi SR, Uyar A, Jackson HM, Acklin CJ, Wang X, Sasner M, Carter GW, Howell GR. Staging Alzheimer's Disease in the Brain and Retina of B6.APP/PS1 Mice by Transcriptional Profiling. Journal of Alzheimer's Disease : Jad. PMID 31929156 DOI: 10.3233/JAD-190793   
2020 Balupuri A, Choi KE, Kang NS. Aggregation Mechanism of Alzheimer's Amyloid β-Peptide Mediated by α-Strand/α-Sheet Structure. International Journal of Molecular Sciences. 21. PMID 32046006 DOI: 10.3390/ijms21031094   
2020 Jara-Moreno D, Riveros A, Barriga A, Kogan MJ, Delporte C. Inhibition of β-amyloid aggregation of Ugni molinae extracts. Current Pharmaceutical Design. PMID 31931693 DOI: 10.2174/1381612826666200113160840   
2020 Song XJ, Zhou HY, Sun YX, Huang HC. Inhibitory effects of curcumin on HO-induced cell damage and APP expression and processing in SH-SY5Y cells transfected with APP gene with Swedish mutation. Molecular Biology Reports. PMID 32036572 DOI: 10.1007/s11033-020-05305-w   
2020 Mouchlis VD, Melagraki G, Zacharia LC, Afantitis A. Computer-Aided Drug Design of β-Secretase, γ-Secretase and Anti-Tau Inhibitors for the Discovery of Novel Alzheimer's Therapeutics. International Journal of Molecular Sciences. 21. PMID 31973122 DOI: 10.3390/ijms21030703   
2020 Wisniewski T, Drummond E. APOE-amyloid interaction: Therapeutic targets. Neurobiology of Disease. 104784. PMID 32027932 DOI: 10.1016/j.nbd.2020.104784   
2020 Uddin MS, Kabir MT, Tewari D, Mathew B, Aleya L. Emerging signal regulating potential of small molecule biflavonoids to combat neuropathological insults of Alzheimer's disease. The Science of the Total Environment. 700: 134836. PMID 31704512 DOI: 10.1016/j.scitotenv.2019.134836   
2020 Gancar M, Ho K, Mohid SA, Thai NQ, Bednarikova Z, Nguyen HL, Bhunia A, Nepovimova E, Li MS, Gazova Z. 7-MEOTA and 2-aminobenzothiazole heterodimers: structure-mechanism relationship of amyloid inhibitors based on rational design. Acs Chemical Neuroscience. PMID 32011847 DOI: 10.1021/acschemneuro.9b00419   
2020 Ngo ST, Nguyen PH, Derreumaux P. Stability of Aβ11-40 Trimers with Parallel and Antiparallel β-Sheet Organizations in a Membrane-Mimicking Environment by Replica Exchange Molecular Dynamics Simulation. The Journal of Physical Chemistry. B. PMID 31931566 DOI: 10.1021/acs.jpcb.9b10982   
2020 Huang LK, Chao SP, Hu CJ. Clinical trials of new drugs for Alzheimer disease. Journal of Biomedical Science. 27: 18. PMID 31906949 DOI: 10.1186/s12929-019-0609-7   
2020 Wolfe MS. Unraveling the complexity of γ-secretase. Seminars in Cell & Developmental Biology. PMID 31980377 DOI: 10.1016/j.semcdb.2020.01.005   
2020 Zhang W, Luo P. Myocardial Infarction Predisposes Neurodegenerative Diseases. Journal of Alzheimer's Disease : Jad. PMID 32065796 DOI: 10.3233/JAD-191225   
2020 Dutta MS, Basu S. Identifying the key residues instrumental in imparting stability to amyloid beta protofibrils - a comparative study using MD simulations of 17-42 residues. Journal of Biomolecular Structure & Dynamics. 1-28. PMID 31900057 DOI: 10.1080/07391102.2019.1711192   
2020 Xu C, Apostolova LG, Oblak AL, Gao S. Association of Hypercholesterolemia with Alzheimer's Disease Pathology and Cerebral Amyloid Angiopathy. Journal of Alzheimer's Disease : Jad. PMID 31929164 DOI: 10.3233/JAD-191023   
2020 Lee SB, Yang SY, Thao NP, Seo DG, Kim S, Ma CT, Park SY, Kim YH, Yang HO. Protective Effects of Compounds from against Amyloid Beta Production in Vitro and Scopolamine-Induced Memory Impairment in Vivo. Journal of Natural Products. PMID 32031796 DOI: 10.1021/acs.jnatprod.9b00543   
2020 Malampati S, Song JX, Chun-Kit Tong B, Nalluri A, Yang CB, Wang Z, Gopalkrishnashetty Sreenivasmurthy S, Zhu Z, Liu J, Su C, Krishnamoorthi S, Iyaswamy A, Cheung KH, Lu JH, Li AM. Targeting Aggrephagy for the Treatment of Alzheimer's Disease. Cells. 9. PMID 32012902 DOI: 10.3390/cells9020311   
2020 Gadhave K, Gehi BR, Kumar P, Xue B, Uversky VN, Giri R. The dark side of Alzheimer's disease: unstructured biology of proteins from the amyloid cascade signaling pathway. Cellular and Molecular Life Sciences : Cmls. PMID 31894361 DOI: 10.1007/s00018-019-03414-9   
2020 Lam YPY, Wootton CA, Hands-Portman I, Wei J, Chiu CKC, Romero-Canelon I, Lermyte F, Barrow MP, O'Connor PB. Determination of the Aggregate Binding Site of Amyloid Protofibrils Using Electron Capture Dissociation Tandem Mass Spectrometry. Journal of the American Society For Mass Spectrometry. PMID 31922736 DOI: 10.1021/jasms.9b00053   
2020 Fan Q, Liu Y, Wang X, Zhang Z, Fu Y, Liu L, Wang P, Ma H, Ma H, Seeram NP, Zheng J, Zhou F. Ginnalin A Inhibits Aggregation, Reverses Fibrillogenesis and Alleviates Cytotoxicity of Amyloid (1-42). Acs Chemical Neuroscience. PMID 31967782 DOI: 10.1021/acschemneuro.9b00673   
2020 Saeed AA, Ghallab EH, Shehata M, Zekri ARN, Ahmed OS. Impact nano- conjugate on Drosophila for early diagnosis of Alzheimer's disease. Nanotechnology. PMID 32045897 DOI: 10.1088/1361-6528/ab7535   
2020 Singh RK. Recent trends in management of Alzheimer's disease: Current therapeutic options and drug repurposing approaches. Current Neuropharmacology. PMID 31989900 DOI: 10.2174/1570159X18666200128121920   
2020 Tan X, Luo Y, Pi D, Xia L, Li Z, Tu Q. miR-340 reduces accumulation of amyloid-β through targeting BACE1 (β-site amyloid precursor protein cleaving enzyme 1) in Alzheimer' s disease. Current Neurovascular Research. PMID 31957613 DOI: 10.2174/1567202617666200117103931   
2020 Li M, Meng Y, Chu B, Shen Y, Liu X, Ding M, Song C, Cao X, Wang P, Xu L, Wang Y, Xu S, Bi J, Xie Z. Orexin-A aggravates cytotoxicity and mitochondrial impairment in SH-SY5Y cells transfected with APPswe via p38 MAPK pathway. Annals of Translational Medicine. 8: 5. PMID 32055596 DOI: 10.21037/atm.2019.11.68   
2020 Yu Z, Dong W, Wu S, Shen J, Zhao W, Ding L, Liu J, Zheng F. Identification of ovalbumin-derived peptides as multi-target inhibitors of AChE, BChE and BACE1. Journal of the Science of Food and Agriculture. PMID 31997357 DOI: 10.1002/jsfa.10295   
2020 Kaplow J, Vandijck M, Gray J, Kanekiyo M, Huyck E, Traynham CJ, Esquivel R, Fagan AM, Luthman J. Concordance of Lumipulse cerebrospinal fluid t-tau/Aβ42 ratio with amyloid PET status. Alzheimer's & Dementia : the Journal of the Alzheimer's Association. 16: 144-152. PMID 31914216 DOI: 10.1002/alz.12000   
2020 Tambini MD, Norris KA, D'Adamio L. Opposite changes in APP processing and human Aβ levels in rats carrying either a protective or a pathogenic APP mutation. Elife. 9. PMID 32022689 DOI: 10.7554/eLife.52612   
2020 Bolarinwa O, Li C, Khadka N, Li Q, Wang Y, Pan J, Cai J. γ-AApeptides-based Small Molecule Ligands That Disaggregate Human Islet Amyloid Polypeptide. Scientific Reports. 10: 95. PMID 31919432 DOI: 10.1038/s41598-019-56500-0   
2020 Du Y, Liu X, Zhu X, Liu Y, Wang X, Wu X. Activating Transcription Factor 6 reduces Aβ1-42 and restores memory in Alzheimer's disease model mice. The International Journal of Neuroscience. 1-11. PMID 31928492 DOI: 10.1080/00207454.2020.1715977   
2020 Wang L, Liu S, Xu J, Watanabe N, Di J, Wei W, Mayo KH, Li J, Li X. A traditional Chinese medicine YXQN reduces amyloid-induced cytotoxicity by inhibiting Aβ42 aggregation and fibril formation. Current Pharmaceutical Design. PMID 32031066 DOI: 10.2174/1381612826666200207120602   
2020 Jeon Y, Lee JH, Choi B, Won SY, Cho KS. Genetic Dissection of Alzheimer's Disease Using Models. International Journal of Molecular Sciences. 21. PMID 32019113 DOI: 10.3390/ijms21030884   
2020 Lopez OL, Klunk WE, Mathis CA, Snitz BE, Chang Y, Tracy RP, Kuller LH. Relationship of amyloid-β1-42 in blood and brain amyloid: Ginkgo Evaluation of Memory Study. Brain Communications. 2: fcz038. PMID 31998865 DOI: 10.1093/braincomms/fcz038   
2020 Hashiguchi D, Campos HC, Wuo-Silva R, Faber J, Gomes da Silva S, Coppi AA, Arida RM, Longo BM. Resistance Exercise Decreases Amyloid Load and Modulates Inflammatory Responses in the APP/PS1 Mouse Model for Alzheimer's Disease. Journal of Alzheimer's Disease : Jad. PMID 31958083 DOI: 10.3233/JAD-190729   
2020 Dong Y, Stewart T, Bai L, Li X, Xu T, Iliff J, Shi M, Zheng D, Yuan L, Wei T, Yang X, Zhang J. Coniferaldehyde attenuates Alzheimer's pathology activation of Nrf2 and its targets. Theranostics. 10: 179-200. PMID 31903114 DOI: 10.7150/thno.36722   
2020 Ichimata S, Hata Y, Abe R, Yoshinaga T, Katoh N, Kametani F, Yazaki M, Sekijima Y, Ehara T, Nishida N. An autopsy case of amyloid tubulopathy exhibiting characteristic spheroid-type deposition. Virchows Archiv : An International Journal of Pathology. PMID 31932919 DOI: 10.1007/s00428-019-02740-4   
2020 Roy ER, Wang B, Wan YW, Chiu GS, Cole AL, Yin Z, Propson NE, Xu Y, Jankowsky JL, Liu Z, Lee VM, Trojanowski JQ, Ginsberg SD, Butovsky O, Zheng H, et al. Type I interferon response drives neuroinflammation and synapse loss in Alzheimer disease. The Journal of Clinical Investigation. PMID 31917687 DOI: 10.1172/JCI133737   
2020 Castanho I, Murray TK, Hannon E, Jeffries A, Walker E, Laing E, Baulf H, Harvey J, Bradshaw L, Randall A, Moore K, O'Neill P, Lunnon K, Collier DA, Ahmed Z, et al. Transcriptional Signatures of Tau and Amyloid Neuropathology. Cell Reports. 30: 2040-2054.e5. PMID 32049030 DOI: 10.1016/j.celrep.2020.01.063   
2020 Sampson TR, Challis C, Jain N, Moiseyenko A, Ladinsky MS, Shastri GG, Thron T, Needham BD, Horvath I, Debelius JW, Janssen S, Knight R, Wittung-Stafshede P, Gradinaru V, Chapman M, et al. A gut bacterial amyloid promotes α-synuclein aggregation and motor impairment in mice. Elife. 9. PMID 32043464 DOI: 10.7554/eLife.53111