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Huiyuan Li, Ph.D. - Publications

Affiliations: 
Neurology University of California, Los Angeles, Los Angeles, CA 
Area:
Alzheimer's disease, Drug development
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12 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2016 Li H, Rahimi F, Bitan G. Modulation of amyloid β-protein (Aβ) assembly by homologous C-terminal fragments as a strategy for inhibiting Aβ toxicity. Acs Chemical Neuroscience. PMID 27322435 DOI: 10.1021/Acschemneuro.6B00154  0.71
2015 Bailey LD, Kalyana Sundaram RV, Li H, Duffy C, Aneja R, Rosemary Bastian A, Holmes AP, Kamanna K, Rashad AA, Chaiken I. Disulfide sensitivity in the Env protein underlies lytic inactivation of HIV-1 by peptide triazole thiols. Acs Chemical Biology. PMID 26458166 DOI: 10.1021/Acschembio.5B00381  0.341
2015 Zheng X, Wu C, Liu D, Li H, Bitan G, Shea JE, Bowers MT. Mechanism of C-Terminal Fragments of Amyloid β-Protein as Aβ Inhibitors: Do C-Terminal Interactions Play a Key Role in Their Inhibitory Activity? The Journal of Physical Chemistry. B. PMID 26439281 DOI: 10.1021/Acs.Jpcb.5B08177  0.659
2013 Li H, Aneja R, Chaiken I. Click chemistry in peptide-based drug design. Molecules (Basel, Switzerland). 18: 9797-817. PMID 23959192 DOI: 10.3390/Molecules18089797  0.374
2013 Long YQ, Huang SX, Zawahir Z, Xu ZL, Li H, Sanchez TW, Zhi Y, De Houwer S, Christ F, Debyser Z, Neamati N. Design of cell-permeable stapled peptides as HIV-1 integrase inhibitors. Journal of Medicinal Chemistry. 56: 5601-12. PMID 23758584 DOI: 10.1021/Jm4006516  0.382
2012 Solomonov I, Korkotian E, Born B, Feldman Y, Bitler A, Rahimi F, Li H, Bitan G, Sagi I. Zn2+-Aβ40 complexes form metastable quasi-spherical oligomers that are cytotoxic to cultured hippocampal neurons. The Journal of Biological Chemistry. 287: 20555-64. PMID 22528492 DOI: 10.1074/Jbc.M112.344036  0.643
2012 Li H, Zemel R, Lopes DH, Monien BH, Bitan G. A two-step strategy for structure-activity relationship studies of N-methylated aβ42 C-terminal fragments as aβ42 toxicity inhibitors. Chemmedchem. 7: 515-22. PMID 22307963 DOI: 10.1002/Cmdc.201100584  0.679
2012 Gessel MM, Wu C, Li H, Bitan G, Shea JE, Bowers MT. Aβ(39-42) modulates Aβ oligomerization but not fibril formation. Biochemistry. 51: 108-17. PMID 22129303 DOI: 10.1021/Bi201520B  0.63
2011 Li H, Du Z, Lopes DH, Fradinger EA, Wang C, Bitan G. C-terminal tetrapeptides inhibit Aβ42-induced neurotoxicity primarily through specific interaction at the N-terminus of Aβ42. Journal of Medicinal Chemistry. 54: 8451-60. PMID 22087474 DOI: 10.1021/Jm200982P  0.64
2010 Li H, Monien BH, Lomakin A, Zemel R, Fradinger EA, Tan M, Spring SM, Urbanc B, Xie CW, Benedek GB, Bitan G. Mechanistic investigation of the inhibition of Abeta42 assembly and neurotoxicity by Abeta42 C-terminal fragments. Biochemistry. 49: 6358-64. PMID 20568734 DOI: 10.1021/Bi100773G  0.722
2010 Li H, Monien BH, Fradinger EA, Urbanc B, Bitan G. Biophysical characterization of Abeta42 C-terminal fragments: inhibitors of Abeta42 neurotoxicity. Biochemistry. 49: 1259-67. PMID 20050679 DOI: 10.1021/Bi902075H  0.73
2008 Fradinger EA, Monien BH, Urbanc B, Lomakin A, Tan M, Li H, Spring SM, Condron MM, Cruz L, Xie CW, Benedek GB, Bitan G. C-terminal peptides coassemble into Abeta42 oligomers and protect neurons against Abeta42-induced neurotoxicity. Proceedings of the National Academy of Sciences of the United States of America. 105: 14175-80. PMID 18779585 DOI: 10.1073/Pnas.0807163105  0.727
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