| Year |
Citation |
Score |
| 2015 |
Lopes DH, Attar A, Nair G, Hayden EY, Du Z, McDaniel K, Dutt S, Bravo-Rodriguez K, Mittal S, Klärner FG, Wang C, Sanchez-Garcia E, Schrader T, Bitan G. Molecular Tweezers Inhibit Islet Amyloid Polypeptide Assembly and Toxicity by a New Mechanism. Acs Chemical Biology. 10: 1555-69. PMID 25844890 DOI: 10.1021/Acschembio.5B00146 |
0.612 |
|
| 2013 |
Connors CR, Rosenman DJ, Lopes DH, Mittal S, Bitan G, Sorci M, Belfort G, Garcia A, Wang C. Tranilast binds to aβ monomers and promotes aβ fibrillation. Biochemistry. 52: 3995-4002. PMID 23679559 DOI: 10.1021/Bi400426T |
0.603 |
|
| 2012 |
Sinha S, Lopes DH, Bitan G. A key role for lysine residues in amyloid β-protein folding, assembly, and toxicity. Acs Chemical Neuroscience. 3: 473-81. PMID 22860216 DOI: 10.1021/Cn3000247 |
0.655 |
|
| 2012 |
Lopes DH, Sinha S, Rosensweig C, Bitan G. Application of photochemical cross-linking to the study of oligomerization of amyloidogenic proteins. Methods in Molecular Biology (Clifton, N.J.). 849: 11-21. PMID 22528080 DOI: 10.1007/978-1-61779-551-0_2 |
0.612 |
|
| 2012 |
Novick PA, Lopes DH, Branson KM, Esteras-Chopo A, Graef IA, Bitan G, Pande VS. Design of β-amyloid aggregation inhibitors from a predicted structural motif. Journal of Medicinal Chemistry. 55: 3002-10. PMID 22420626 DOI: 10.1021/Jm201332P |
0.622 |
|
| 2012 |
Li H, Zemel R, Lopes DH, Monien BH, Bitan G. A two-step strategy for structure-activity relationship studies of N-methylated aβ42 C-terminal fragments as aβ42 toxicity inhibitors. Chemmedchem. 7: 515-22. PMID 22307963 DOI: 10.1002/Cmdc.201100584 |
0.542 |
|
| 2012 |
Bitan G, Sinha S, Lopes D, Du Z, Maiti P, Klärner F, Schrader T, Wang C. P4-051: Structural insight into the mechanism of beta-amyloid toxicity and its inhibition by small molecules Alzheimer's & Dementia. 8: P653-P653. DOI: 10.1016/J.Jalz.2012.05.1753 |
0.562 |
|
| 2011 |
Li H, Du Z, Lopes DH, Fradinger EA, Wang C, Bitan G. C-terminal tetrapeptides inhibit Aβ42-induced neurotoxicity primarily through specific interaction at the N-terminus of Aβ42. Journal of Medicinal Chemistry. 54: 8451-60. PMID 22087474 DOI: 10.1021/Jm200982P |
0.603 |
|
| 2011 |
Moskovitz J, Maiti P, Lopes DH, Oien DB, Attar A, Liu T, Mittal S, Hayes J, Bitan G. Induction of methionine-sulfoxide reductases protects neurons from amyloid β-protein insults in vitro and in vivo. Biochemistry. 50: 10687-97. PMID 22059533 DOI: 10.1021/Bi201426B |
0.581 |
|
| 2011 |
Sinha S, Lopes DH, Du Z, Pang ES, Shanmugam A, Lomakin A, Talbiersky P, Tennstaedt A, McDaniel K, Bakshi R, Kuo PY, Ehrmann M, Benedek GB, Loo JA, Klärner FG, et al. Lysine-specific molecular tweezers are broad-spectrum inhibitors of assembly and toxicity of amyloid proteins. Journal of the American Chemical Society. 133: 16958-69. PMID 21916458 DOI: 10.1021/Ja206279B |
0.636 |
|
| 2011 |
Lopes D, Sinha S, Bitan G. A key role for lysine residues in amyloid-β protein folding, assembly, and toxicity Alzheimers & Dementia. 7. DOI: 10.1016/J.Jalz.2011.05.1349 |
0.608 |
|
| 2007 |
Lopes DH, Meister A, Gohlke A, Hauser A, Blume A, Winter R. Mechanism of islet amyloid polypeptide fibrillation at lipid interfaces studied by infrared reflection absorption spectroscopy. Biophysical Journal. 93: 3132-41. PMID 17660321 DOI: 10.1529/Biophysj.107.110635 |
0.366 |
|
| 2004 |
Lopes DH, Colin C, Degaki TL, de Sousa AC, Vieira MN, Sebollela A, Martinez AM, Bloch C, Ferreira ST, Sogayar MC. Amyloidogenicity and cytotoxicity of recombinant mature human islet amyloid polypeptide (rhIAPP). The Journal of Biological Chemistry. 279: 42803-10. PMID 15292167 DOI: 10.1074/Jbc.M406108200 |
0.402 |
|
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