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Nan Zhu, Ph.D. - Publications

Affiliations: 
2007 Boston University, Boston, MA, United States 
Area:
Molecular Biology
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24 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2020 Lenard A, Xie HM, Pastuer T, Shank T, Libbrecht C, Kingsley M, Riedel SS, Yuan ZF, Zhu N, Neff T, Bernt KM. Epigenetic regulation of protein translation in KMT2A-rearranged AML. Experimental Hematology. PMID 32437908 DOI: 10.1016/j.exphem.2020.04.007  0.312
2019 Izaguirre-Carbonell J, Christiansen L, Burns R, Schmitz J, Li C, Mokry RL, Bluemn T, Zheng Y, Shen J, Carlson KS, Rao S, Wang D, Zhu N. Critical role of Jumonji domain of JMJD1C in MLL-rearranged leukemia. Blood Advances. 3: 1499-1511. PMID 31076406 DOI: 10.1182/Bloodadvances.2018026054  0.37
2019 Deshpande A, Chen BR, Zhao L, Saddoris K, Kerr M, Zhu N, Mali P, Deshpande AJ. Investigation of Genetic Dependencies Using CRISPR-Cas9-based Competition Assays. Journal of Visualized Experiments : Jove. PMID 30663717 DOI: 10.3791/58710  0.373
2017 Olp M, Zhu N, Smith B. Metabolically-derived lysine acylations and neighboring modifications tune BET bromodomain binding to histone H4. Biochemistry. PMID 28945351 DOI: 10.1021/Acs.Biochem.7B00595  0.324
2016 Danis E, Yamauchi T, Echanique K, Zhang X, Haladyna JN, Riedel SS, Zhu N, Xie H, Orkin SH, Armstrong SA, Bernt KM, Neff T. Ezh2 Controls an Early Hematopoietic Program and Growth and Survival Signaling in Early T Cell Precursor Acute Lymphoblastic Leukemia. Cell Reports. PMID 26904942 DOI: 10.1016/J.Celrep.2016.01.064  0.394
2016 Zhu N, Chen M, Eng R, DeJong J, Sinha AU, Rahnamay NF, Koche R, Al-Shahrour F, Minehart JC, Chen CW, Deshpande AJ, Xu H, Chu SH, Ebert BL, Roeder RG, et al. MLL-AF9- and HOXA9-mediated acute myeloid leukemia stem cell self-renewal requires JMJD1C. The Journal of Clinical Investigation. PMID 26878175 DOI: 10.1172/Jci82978  0.357
2015 Chen M, Zhu N, Liu X, Laurent B, Tang Z, Eng R, Shi Y, Armstrong SA, Roeder RG. JMJD1C is required for the survival of acute myeloid leukemia by functioning as a coactivator for key transcription factors. Genes & Development. 29: 2123-39. PMID 26494788 DOI: 10.1101/Gad.267278.115  0.404
2015 Danis E, Yamauchi T, Echanique K, Haladyna J, Kalkur R, Riedel S, Zhu N, Xie H, Bernt KM, Orkin SH, Armstrong SA, Neff T. Inactivation of Eed Impedes MLL-AF9 Mediated Leukemogenesis Through Cdkn2a-Dependent and Cdkn2a-Independent Mechanisms in a Murine Model. Experimental Hematology. PMID 26118502 DOI: 10.1016/J.Exphem.2015.06.005  0.423
2015 Chen CW, Koche RP, Sinha AU, Deshpande AJ, Zhu N, Eng R, Doench JG, Xu H, Chu SH, Qi J, Wang X, Delaney C, Bernt KM, Root DE, Hahn WC, et al. DOT1L inhibits SIRT1-mediated epigenetic silencing to maintain leukemic gene expression in MLL-rearranged leukemia. Nature Medicine. 21: 335-43. PMID 25822366 DOI: 10.1038/Nm.3832  0.45
2014 Deshpande AJ, Deshpande A, Sinha AU, Chen L, Chang J, Cihan A, Fazio M, Chen CW, Zhu N, Koche R, Dzhekieva L, Ibáñez G, Dias S, Banka D, Krivtsov A, et al. AF10 regulates progressive H3K79 methylation and HOX gene expression in diverse AML subtypes. Cancer Cell. 26: 896-908. PMID 25464900 DOI: 10.1016/J.Ccell.2014.10.009  0.423
2014 Huang CH, Lujambio A, Zuber J, Tschaharganeh DF, Doran MG, Evans MJ, Kitzing T, Zhu N, de Stanchina E, Sawyers CL, Armstrong SA, Lewis JS, Sherr CJ, Lowe SW. CDK9-mediated transcription elongation is required for MYC addiction in hepatocellular carcinoma. Genes & Development. 28: 1800-14. PMID 25128497 DOI: 10.1101/Gad.244368.114  0.302
2014 Danis E, Yamauchi T, Echanique K, Haladyna J, Xie H, Zhu N, Riedel S, Bernt KM, Orkin SH, Armstrong SA, Neff T. Context Dependent Role of Polycomb Repressive Complex 2 in Acute Leukemia Blood. 124: 610-610. DOI: 10.1182/Blood.V124.21.610.610  0.436
2013 Lobry C, Ntziachristos P, Ndiaye-Lobry D, Oh P, Cimmino L, Zhu N, Araldi E, Hu W, Freund J, Abdel-Wahab O, Ibrahim S, Skokos D, Armstrong SA, Levine RL, Park CY, et al. Notch pathway activation targets AML-initiating cell homeostasis and differentiation. The Journal of Experimental Medicine. 210: 301-19. PMID 23359070 DOI: 10.1084/Jem.20121484  0.315
2013 Tam WF, Hähnel PS, Schüler A, Lee BH, Okabe R, Zhu N, Pante SV, Raffel G, Mercher T, Wernig G, Bockamp E, Sasca D, Kreft A, Robinson GW, Hennighausen L, et al. STAT5 is crucial to maintain leukemic stem cells in acute myelogenous leukemias induced by MOZ-TIF2. Cancer Research. 73: 373-84. PMID 23149921 DOI: 10.1158/0008-5472.Can-12-0255  0.308
2013 David Chen C, Sinha AU, Qi J, Deshpande AJ, Zhu N, Koche R, Eng R, Chang J, Hahn WC, Bradner JE, Armstrong SA. Genome-Wide RNAi Screen Identifies The Mechanistic Role For DOT1L In MLL-Rearranged Leukemia Blood. 122: 598-598. DOI: 10.1182/Blood.V122.21.598.598  0.454
2013 Deshpande AJ, Chen L, Sinha AU, Zhu N, Chen D, Chang J, Krivtsov AV, Bernt K, Bradner JE, Armstrong SA. Regulation Of Normal and Malignant Hoxa Gene Expression Through Higher H3K79 Methylated States Blood. 122: 2492-2492. DOI: 10.1182/Blood.V122.21.2492.2492  0.432
2012 Neff T, Sinha AU, Kluk MJ, Zhu N, Khattab MH, Stein L, Xie H, Orkin SH, Armstrong SA. Polycomb repressive complex 2 is required for MLL-AF9 leukemia. Proceedings of the National Academy of Sciences of the United States of America. 109: 5028-33. PMID 22396593 DOI: 10.1073/Pnas.1202258109  0.423
2012 Onder TT, Kara N, Cherry A, Sinha AU, Zhu N, Bernt KM, Cahan P, Marcarci BO, Unternaehrer J, Gupta PB, Lander ES, Armstrong SA, Daley GQ. Chromatin-modifying enzymes as modulators of reprogramming. Nature. 483: 598-602. PMID 22388813 DOI: 10.1038/Nature10953  0.431
2012 Trowbridge JJ, Sinha AU, Zhu N, Li M, Armstrong SA, Orkin SH. Haploinsufficiency of Dnmt1 impairs leukemia stem cell function through derepression of bivalent chromatin domains. Genes & Development. 26: 344-9. PMID 22345515 DOI: 10.1101/gad.184341.111  0.405
2012 Liu J, Mercher T, Scholl C, Brumme K, Gilliland DG, Zhu N. A functional role for the histone demethylase UTX in normal and malignant hematopoietic cells. Experimental Hematology. 40: 487-98.e3. PMID 22306297 DOI: 10.1016/J.Exphem.2012.01.017  0.405
2011 Bernt KM, Zhu N, Sinha AU, Vempati S, Faber J, Krivtsov AV, Feng Z, Punt N, Daigle A, Bullinger L, Pollock RM, Richon VM, Kung AL, Armstrong SA. MLL-rearranged leukemia is dependent on aberrant H3K79 methylation by DOT1L. Cancer Cell. 20: 66-78. PMID 21741597 DOI: 10.1016/J.Ccr.2011.06.010  0.433
2010 Zhu N, Hansen U. Transcriptional regulation by HMGN proteins. Biochimica Et Biophysica Acta. 1799: 74-9. PMID 20123070 DOI: 10.1016/J.Bbagrm.2009.11.006  0.565
2010 Bernt KM, Zhu N, Faber J, Punt N, Pollock RM, Richon VM, Kung AL, Armstrong S. Demonstration of a Role for Dot1l In MLL-Rearranged Leukemia Using a Conditional Loss of Function Model Blood. 116: 62-62. DOI: 10.1182/Blood.V116.21.62.62  0.419
2007 Zhu N, Hansen U. HMGN1 modulates estrogen-mediated transcriptional activation through interactions with specific DNA-binding transcription factors. Molecular and Cellular Biology. 27: 8859-73. PMID 17938209 DOI: 10.1128/Mcb.01724-07  0.548
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