Lih-Chu Chiou, Ph.D. - Related publications

Pharmacology National Taiwan University, London, Taipei City, Taiwan 
Drug, Pain, Migraine, Tourette, Schizophrenia, Alzheimer’s disease, Obesity
NOTE: We are testing a new system for identifying relevant work based on semantic analysis that identifies similarities between recently published papers and the current author's publications. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches.
50 most relevant papers in past 60 days:
Year Citation  Score
2020 Emerich BL, Ferreira RCM, Machado-de-Avila RA, Resende JM, Duarte IDG, de Lima ME. PnAn13, an antinociceptive synthetic peptide inspired in the toxin PnTx4(6-1) (δ-Ctenitoxin-Pn1a). Toxicon: X. 7: 100045. PMID 32875290 DOI: 10.1016/j.toxcx.2020.100045   
2020 Zhou P, Li Y, Yong Z, Chen M, Zhang Y, Su R, Gong Z. Thienorphine induces antinociception without dependence through activation of κ- and δ-, and partial activation of μ- opioid receptor. Brain Research. 147083. PMID 32871137 DOI: 10.1016/j.brainres.2020.147083   
2020 Derouiche L, Pierre F, Doridot S, Ory S, Massotte D. Heteromerization of Endogenous Mu and Delta Opioid Receptors Induces Ligand-Selective Co-Targeting to Lysosomes. Molecules (Basel, Switzerland). 25. PMID 33007971 DOI: 10.3390/molecules25194493   
2020 Dasgupta P, Günther T, Reinscheid RK, Zaveri NT, Schulz S. Rapid assessment of G protein signaling of four opioid receptors using a real-time fluorescence-based membrane potential assay. European Journal of Pharmacology. 173640. PMID 33045198 DOI: 10.1016/j.ejphar.2020.173640   
2020 Dasgupta P, Günther T, Reinscheid RK, Zaveri NT, Schulz S. Rapid assessment of G protein signaling of four opioid receptors using a real-time fluorescence-based membrane potential assay. European Journal of Pharmacology. 173640. PMID 33045198 DOI: 10.1016/j.ejphar.2020.173640   
2020 Azevedo Neto J, Costanzini A, De Giorgio R, Lambert DG, Ruzza C, Calò G. Biased versus Partial Agonism in the Search for Safer Opioid Analgesics. Molecules (Basel, Switzerland). 25. PMID 32854452 DOI: 10.3390/molecules25173870   
2020 Gress K, Charipova K, Jung JW, Kaye AD, Paladini A, Varrassi G, Viswanath O, Urits I. A comprehensive review of partial opioid agonists for the treatment of chronic pain. Best Practice & Research. Clinical Anaesthesiology. 34: 449-461. PMID 33004158 DOI: 10.1016/j.bpa.2020.06.003   
2020 Gress K, Charipova K, Jung JW, Kaye AD, Paladini A, Varrassi G, Viswanath O, Urits I. A comprehensive review of partial opioid agonists for the treatment of chronic pain. Best Practice & Research. Clinical Anaesthesiology. 34: 449-461. PMID 33004158 DOI: 10.1016/j.bpa.2020.06.003   
2020 Jin Y, Qiu CY, Wei S, Han L, Liu TT, Hu WP. Potentiation of P2X3 receptor mediated currents by endothelin-1 in rat dorsal root ganglion neurons. Neuropharmacology. 108356. PMID 33069757 DOI: 10.1016/j.neuropharm.2020.108356   
2020 Barnett ME, Knapp BI, Bidlack JM. Unique Pharmacological Properties of the Kappa Opioid Receptor Signaling Through Gz as Shown with Bioluminescence Resonance Energy Tranfer. Molecular Pharmacology. 98: 462-474. PMID 32958572 DOI: 10.1124/mol.120.119404   
2020 Faouzi A, Varga BR, Majumdar S. Biased Opioid Ligands. Molecules (Basel, Switzerland). 25. PMID 32948048 DOI: 10.3390/molecules25184257   
2020 Hino N, Marumo T, Kotani M, Shimazaki T, Kaku-Fukumoto A, Hikichi H, Karasawa JI, Tomishima Y, Komiyama H, Tatsuda E, Nozawa D, Nakamura T, Chaki S. A Novel Potent and Selective Histamine H3 Receptor Antagonist Enerisant: In Vitro Profiles, In Vivo Receptor Occupancy, Wake-Promoting and Pro-cognitive Effects in Rodents. The Journal of Pharmacology and Experimental Therapeutics. PMID 32862143 DOI: 10.1124/jpet.120.000185   
2020 Liu X, Wu Y, Zhou D, Xie Y, Zhou Y, Lu Y, Yang R, Liu S. N‑linoleyltyrosine protects PC12 cells against oxidative damage via autophagy: Possible involvement of CB1 receptor regulation. International Journal of Molecular Medicine. 46: 1827-1837. PMID 33000188 DOI: 10.3892/ijmm.2020.4706   
2020 Cifani C, Micioni Di Bonaventura E, Botticelli L, Del Bello F, Giorgioni G, Pavletić P, Piergentili A, Quaglia W, Bonifazi A, Schepmann D, Wünsch B, Vistoli G, Micioni Di Bonaventura MV. Novel Highly Potent and Selective Sigma1 Receptor Antagonists Effectively Blocking the Binge Eating Episode in Female Rats. Acs Chemical Neuroscience. PMID 32886484 DOI: 10.1021/acschemneuro.0c00456   
2020 Uhelski ML, Bruce D, Speltz R, Wilcox GL, Simone DA. Topical Application of Loperamide/Oxymorphindole, Mu and Delta Opioid Receptor Agonists, Reduces Sensitization of C-fiber Nociceptors that Possess Na1.8. Neuroscience. PMID 32858141 DOI: 10.1016/j.neuroscience.2020.08.022   
2020 García M, Virgili M, Alonso M, Alegret C, Farran J, Fernández B, Bordas M, Pascual R, Burgueño J, Vidal-Torres A, Fernández de Henestrosa AR, Ayet E, Merlos M, Vela JM, Plata-Salamán CR, et al. Discovery of EST73502, a Dual μ-Opioid Receptor Agonist and σ Receptor Antagonist Clinical Candidate for the Treatment of Pain. Journal of Medicinal Chemistry. PMID 33064947 DOI: 10.1021/acs.jmedchem.0c01127   
2020 Walsh KB, Andersen HK. Molecular Pharmacology of Synthetic Cannabinoids: Delineating CB1 Receptor-Mediated Cell Signaling. International Journal of Molecular Sciences. 21. PMID 32854313 DOI: 10.3390/ijms21176115   
2020 Paton K, Atigari D, Kaska S, Prisinzano TE, Kivell BM. . The Journal of Pharmacology and Experimental Therapeutics. PMID 32913006 DOI: 10.1124/jpet.120.000134   
2020 Sarkar A, Adamska-Bartlomiejczyk A, Piekielna-Ciesielska J, Wtorek K, Kluczyk A, Borics A, Janecka A. Design, Synthesis and Functional Analysis of Cyclic Opioid Peptides with Dmt-Tic Pharmacophore. Molecules (Basel, Switzerland). 25. PMID 32957550 DOI: 10.3390/molecules25184260   
2020 González-Naranjo P, Pérez C, Girón R, Sánchez-Robles EM, Martín-Fontelles MI, Carrillo-López N, Martín-Vírgala J, Naves M, Campillo NE, Páez JA. New cannabinoid receptor antagonists as pharmacological tool. Bioorganic & Medicinal Chemistry. 28: 115672. PMID 32912440 DOI: 10.1016/j.bmc.2020.115672   
2020 Andrade F, Rangel-Sandoval C, Rodríguez-Hernández A, López-Dyck E, Elizalde A, Virgen-Ortiz A, Bonales-Alatorre E, Valencia-Cruz G, Sánchez-Pastor E. Capsaicin Causes Vasorelaxation of Rat Aorta through Blocking of L-type Ca Channels and Activation of CB Receptors. Molecules (Basel, Switzerland). 25. PMID 32872656 DOI: 10.3390/molecules25173957   
2020 Reichard KL, Newton KA, Rivera ZMG, Sotero de Menezes PM, Schattauer SS, Land BB, Chavkin C. . Molecular Pharmacology. PMID 32913138 DOI: 10.1124/molpharm.120.000124   
2020 Rossi GC, Bodnar RJ. Interactive Mechanisms of Supraspinal Sites of Opioid Analgesic Action: A Festschrift to Dr. Gavril W. Pasternak. Cellular and Molecular Neurobiology. PMID 32970288 DOI: 10.1007/s10571-020-00961-9   
2020 Papon MA, Le Feuvre Y, Barreda-Gómez G, Favereaux A, Farrugia F, Bouali-Benazzouz R, Nagy F, Rodríguez-Puertas R, Landry M. Spinal Inhibition of GABAB Receptors by the Extracellular Matrix Protein Fibulin-2 in Neuropathic Rats. Frontiers in Cellular Neuroscience. 14: 214. PMID 32765223 DOI: 10.3389/fncel.2020.00214   
2020 Lyons EL, Leone-Kabler S, Kovach AL, Thomas BF, Howlett AC. Cannabinoid receptor subtype influence on neuritogenesis in human SH-SY5Y cells. Molecular and Cellular Neurosciences. 103566. PMID 33049367 DOI: 10.1016/j.mcn.2020.103566   
2020 da Costa FLP, Pinto MCX, Dos Santos DC, Carobin NV, de Jesus ICG, Ferreira LA, Guatimosim S, da Silva JF, de Castro Junior CJ. Ketamine potentiates TRPV1 receptor signaling in the peripheral nociceptive pathways. Biochemical Pharmacology. 114210. PMID 32882205 DOI: 10.1016/j.bcp.2020.114210   
2020 Duarte Y, Cáceres J, Sepúlveda RV, Arriagada D, Olivares P, Díaz-Franulic I, Stehberg J, González-Nilo F. Novel TRPV1 Channel Agonists With Faster and More Potent Analgesic Properties Than Capsaicin. Frontiers in Pharmacology. 11: 1040. PMID 32760273 DOI: 10.3389/fphar.2020.01040   
2020 Velard F, Chatron-Colliet A, Côme D, Ah-Kioon MD, Lin H, Hafsia N, Cohen-Solal M, Ea HK, Lioté F. Adrenomedullin and truncated peptide adrenomedullin(22-52) affect chondrocyte response to apoptotis in vitro: downregulation of FAS protects chondrocyte from cell death. Scientific Reports. 10: 16740. PMID 33028903 DOI: 10.1038/s41598-020-73924-1   
2020 Norel X, Sugimoto Y, Ozen G, Abdelazeem H, Amgoud Y, Bouhadoun A, Bassiouni W, Goepp M, Mani S, Manikpurage HD, Senbel A, Longrois D, Heinemann A, Yao C, Clapp LH. International Union of Basic and Clinical Pharmacology. CIX. Differences and Similarities between Human and Rodent Prostaglandin E Receptors (EP1-4) and Prostacyclin Receptor (IP): Specific Roles in Pathophysiologic Conditions. Pharmacological Reviews. 72: 910-968. PMID 32962984 DOI: 10.1124/pr.120.019331   
2020 Gillis A, Kliewer A, Kelly E, Henderson G, Christie MJ, Schulz S, Canals M. Critical Assessment of G Protein-Biased Agonism at the μ-Opioid Receptor. Trends in Pharmacological Sciences. PMID 33097283 DOI: 10.1016/   
2020 Liu JJ, Chiu YT, Chen C, Huang P, Mann M, Liu-Chen LY. Pharmacological and phosphoproteomic approaches to roles of protein kinase C in kappa opioid receptor-mediated effects in mice. Neuropharmacology. 108324. PMID 32976891 DOI: 10.1016/j.neuropharm.2020.108324   
2020 Popa R, Kamble SH, Kanumuri RS, King TI, Berthold EC, Intagliata S, Sharma A, McCurdy CR. Bioanalytical method development and pharmacokinetics of MCI-92, a sigma-1 receptor ligand. Journal of Pharmaceutical and Biomedical Analysis. 191: 113610. PMID 32971495 DOI: 10.1016/j.jpba.2020.113610   
2020 Szőke É, Bálint M, Hetényi C, Markovics A, Elekes K, Pozsgai G, Szűts T, Kéri G, Őrfi L, Sándor Z, Szolcsányi J, Pintér E, Helyes Z. Small molecule somatostatin receptor subtype 4 (sst) agonists are novel anti-inflammatory and analgesic drug candidates. Neuropharmacology. 178: 108198. PMID 32739276 DOI: 10.1016/j.neuropharm.2020.108198   
2020 Shi JJ, Jia KH, Sun H, Gunosewoyo H, Yang F, Tang J, Luo J, Yu L. Synthesis and pharmacological evaluation of σ2 receptor ligands based on a 3-alkoxyisoxazole scaffold: potential antitumor effects against osteosarcoma. Chemmedchem. PMID 32964625 DOI: 10.1002/cmdc.202000461   
2020 Wang H, Zhang Y, Ma X, Wang W, Xu X, Huang M, Xu L, Shi H, Yuan T, Jiang W, Wang A, Xu T. Spinal TLR4/P2X7 Receptor-Dependent NLRP3 Inflammasome Activation Contributes to the Development of Tolerance to Morphine-Induced Antinociception. Journal of Inflammation Research. 13: 571-582. PMID 33061523 DOI: 10.2147/JIR.S266995   
2020 Saheb Sharif-Askari N, Saheb Sharif-Askari F, Mdkhana B, Al Heialy S, Ratemi E, Alghamdi M, Abusnana S, Kashour T, Hamid Q, Halwani R. Effect of common medications on the expression of SARS-CoV-2 entry receptors in liver tissue. Archives of Toxicology. PMID 32808185 DOI: 10.1007/s00204-020-02869-1   
2020 Xie XY, Li YY, Ma WH, Chen AF, Sun YT, Lee JY, Riad A, Xu DH, Mach RH, Huang YS. Synthesis, binding, and functional properties of tetrahydroisoquinolino-2-alkyl phenones as selective σR/TMEM97 ligands. European Journal of Medicinal Chemistry. 209: 112906. PMID 33049607 DOI: 10.1016/j.ejmech.2020.112906   
2020 Andrejew R, Oliveira-Giacomelli Á, Ribeiro DE, Glaser T, Arnaud-Sampaio VF, Lameu C, Ulrich H. The P2X7 Receptor: Central Hub of Brain Diseases. Frontiers in Molecular Neuroscience. 13: 124. PMID 32848594 DOI: 10.3389/fnmol.2020.00124   
2020 Corboz MR, Salvail W, Gagnon S, LaSala D, Laurent CE, Salvail D, Chen KJ, Cipolla D, Perkins WR, Chapman RW. Prostanoid receptor subtypes involved in treprostinil-mediated vasodilation of rat pulmonary arteries and in treprostinil-mediated inhibition of collagen gene expression of human lung fibroblasts. Prostaglandins & Other Lipid Mediators. 106486. PMID 33011365 DOI: 10.1016/j.prostaglandins.2020.106486   
2020 Senn L, Cannazza G, Biagini G. Receptors and Channels Possibly Mediating the Effects of Phytocannabinoids on Seizures and Epilepsy. Pharmaceuticals (Basel, Switzerland). 13. PMID 32751761 DOI: 10.3390/ph13080174   
2020 Altarifi AA, Moerke MJ, Alsalem MI, Negus SS. Preclinical assessment of tramadol abuse potential: Effects of acute and repeated tramadol on intracranial self-stimulation in rats. Journal of Psychopharmacology (Oxford, England). 269881120944153. PMID 32842842 DOI: 10.1177/0269881120944153   
2020 Chiang M, Back HM, Lee JB, Oh S, Guo T, Girgis S, Park C, Haroutounian S, Kagan L. Pharmacokinetic Modeling of the Impact of P-glycoprotein on Ondansetron Disposition in the Central Nervous System. Pharmaceutical Research. 37: 205. PMID 32989520 DOI: 10.1007/s11095-020-02929-2   
2020 Bourdet DL, Yeola S, Hegde SS, Colson PJ, Barnes CN, Borin MT. . Drug Metabolism and Disposition: the Biological Fate of Chemicals. PMID 32978223 DOI: 10.1124/dmd.120.000103   
2020 Piltonen M, Krokhotin A, Parisien M, Bérubé P, Djambazian H, Sladek R, Dokholyan NV, Shabalina SA, Diatchenko L. Alternative Splicing of Opioid Receptor Genes Shows a Conserved Pattern for 6TM Receptor Variants. Cellular and Molecular Neurobiology. PMID 33010019 DOI: 10.1007/s10571-020-00971-7   
2020 Penthala NR, Shoeib A, Dachavaram SS, Cabanlong CV, Yang J, Zhan CG, Prather PL, Crooks PA. 7-Azaindolequinuclidinones (7-AIQD): A novel class of cannabinoid 1 (CB1) and cannabinoid 2 (CB2) receptor ligands. Bioorganic & Medicinal Chemistry Letters. 30: 127501. PMID 32882418 DOI: 10.1016/j.bmcl.2020.127501   
2020 Narayan A, Hunkle A, Xu J, Bassoni DL, Pasternak GW, Pan YX. Mu Opioids Induce Biased Signaling at the Full-Length Seven Transmembrane C-Terminal Splice Variants of the mu Opioid Receptor Gene, Oprm1. Cellular and Molecular Neurobiology. PMID 33033993 DOI: 10.1007/s10571-020-00973-5   
2020 Jacobson KA, Salmaso V. Purinergic signaling: Impact of GPCR structures on rational drug design. Chemmedchem. PMID 32803849 DOI: 10.1002/cmdc.202000465   
2020 Yang Q, Lin JN, Sui X, Li H, Kan M, Wang JF, Li J, Zhang Z, Liu XR, Ming ST, Qu XB, Li N. Antiapoptotic effects of velvet antler polypeptides on damaged neurons through the hypothalamic-pituitary-adrenal axis. Journal of Integrative Neuroscience. 19: 469-477. PMID 33070526 DOI: 10.31083/j.jin.2020.03.167   
2020 Greenfield DA, Schmidt HR, Skiba MA, Mandler MD, Anderson JR, Sliz P, Kruse AC. Virtual Screening for Ligand Discovery at the σ Receptor. Acs Medicinal Chemistry Letters. 11: 1555-1561. PMID 32832023 DOI: 10.1021/acsmedchemlett.9b00314   
2020 Sun X, Zhou R, Lei Y, Hu J, Li X. The ligand-gated ion channel P2X7 receptor mediates NLRP3/caspase-1-mediated pyroptosis in cerebral cortical neurons of juvenile rats with sepsis. Brain Research. 147109. PMID 32905819 DOI: 10.1016/j.brainres.2020.147109