Emil Unanue - Publications

Affiliations: 
Washington University, Saint Louis, St. Louis, MO 

173 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2021 Srivastava N, Hu H, Vomund AN, Peterson OJ, Baker RL, Kathryn H, Teyton L, Wan X, Unanue ER. Chromogranin A Deficiency Confers Protection from Autoimmune Diabetes Via Multiple Mechanisms. Diabetes. PMID 34497137 DOI: 10.2337/db21-0513  0.357
2021 Vomund AN, Lichti CF, Peterson OJ, Arbelaez AM, Wan X, Unanue ER. Blood leukocytes recapitulate diabetogenic peptide-MHC-II complexes displayed in the pancreatic islets. The Journal of Experimental Medicine. 218. PMID 33822842 DOI: 10.1084/jem.20202530  0.466
2020 Zakharov PN, Hu H, Wan X, Unanue ER. Single-cell RNA sequencing of murine islets shows high cellular complexity at all stages of autoimmune diabetes. The Journal of Experimental Medicine. 217. PMID 32251514 DOI: 10.1084/jem.20192362  0.323
2020 Wan X, Vomund AN, Peterson OJ, Chervonsky AV, Lichti CF, Unanue ER. Publisher Correction: The MHC-II peptidome of pancreatic islets identifies key features of autoimmune peptides. Nature Immunology. PMID 32238948 DOI: 10.1038/s41590-020-0670-0  0.312
2020 Wan X, Vomund AN, Peterson OJ, Chervonsky AV, Lichti CF, Unanue ER. The MHC-II peptidome of pancreatic islets identifies key features of autoimmune peptides. Nature Immunology. PMID 32152506 DOI: 10.1038/s41590-020-0623-7  0.456
2019 Alspach E, Lussier DM, Miceli AP, Kizhvatov I, DuPage M, Luoma AM, Meng W, Lichti CF, Esaulova E, Vomund AN, Runci D, Ward JP, Gubin MM, Medrano RFV, Arthur CD, ... ... Unanue ER, et al. MHC-II neoantigens shape tumour immunity and response to immunotherapy. Nature. PMID 31645760 DOI: 10.1038/S41586-019-1671-8  0.362
2019 Gioia L, Holt M, Costanzo A, Sharma S, Abe B, Kain L, Nakayama M, Wan X, Su A, Mathews C, Chen YG, Unanue E, Teyton L. Position β57 of I-A controls early anti-insulin responses in NOD mice, linking an MHC susceptibility allele to type 1 diabetes onset. Science Immunology. 4. PMID 31471352 DOI: 10.1126/Sciimmunol.Aaw6329  0.555
2018 Wan X, Unanue ER. Antigen recognition in autoimmune diabetes: a novel pathway underlying disease initiation. Precision Clinical Medicine. 1: 102-110. PMID 30687564 DOI: 10.1093/pcmedi/pby015  0.379
2018 Wan X, Zinselmeyer BH, Zakharov PN, Vomund AN, Taniguchi R, Santambrogio L, Anderson MS, Lichti CF, Unanue ER. Pancreatic islets communicate with lymphoid tissues via exocytosis of insulin peptides. Nature. PMID 30022165 DOI: 10.1038/s41586-018-0341-6  0.411
2018 ALTINDIS E, VOMUND AN, CHOW I, DAMASIO M, KWOK W, UNANUE ER, KAHN CR. Identification of Cross Reactive Insulin Immunogenic Epitopes from Commensal Gut Microbes Diabetes. 67: 95-OR. DOI: 10.2337/Db18-95-Or  0.436
2016 Carrero JA, Ferris ST, Unanue ER. Macrophages and dendritic cells in islets of Langerhans in diabetic autoimmunity: a lesson on cell interactions in a mini-organ. Current Opinion in Immunology. 43: 54-59. PMID 27710840 DOI: 10.1016/j.coi.2016.09.004  0.346
2016 Unanue ER, Ferris ST, Carrero JA. The role of islet antigen presenting cells and the presentation of insulin in the initiation of autoimmune diabetes in the NOD mouse. Immunological Reviews. 272: 183-201. PMID 27319351 DOI: 10.1111/imr.12430  0.391
2016 Ferris ST, Carrero JA, Unanue ER. Antigen presentation events during the initiation of autoimmune diabetes in the NOD mouse. Journal of Autoimmunity. PMID 27021276 DOI: 10.1016/j.jaut.2016.03.007  0.417
2016 Unanue ER, Turk V, Neefjes J. Variations in MHC Class II Antigen Processing and Presentation in Health and Disease. Annual Review of Immunology. PMID 26907214 DOI: 10.1146/Annurev-Immunol-041015-055420  0.329
2015 Vomund AN, Zinselmeyer BH, Hughes J, Calderon B, Valderrama C, Ferris ST, Wan X, Kanekura K, Carrero JA, Urano F, Unanue ER. Beta cells transfer vesicles containing insulin to phagocytes for presentation to T cells. Proceedings of the National Academy of Sciences of the United States of America. 112: E5496-502. PMID 26324934 DOI: 10.1073/pnas.1515954112  0.323
2014 Chakraborty AK, Unanue ER. Herman Eisen (1918-2014). Immunity. 41: 869-70. PMID 25667944 DOI: 10.1016/J.Immuni.2014.12.001  0.347
2014 Ferris ST, Carrero JA, Mohan JF, Calderon B, Murphy KM, Unanue ER. A minor subset of Batf3-dependent antigen-presenting cells in islets of Langerhans is essential for the development of autoimmune diabetes. Immunity. 41: 657-69. PMID 25367577 DOI: 10.1016/J.Immuni.2014.09.012  0.784
2014 Nayak DK, Calderon B, Vomund AN, Unanue ER. ZnT8-reactive T cells are weakly pathogenic in NOD mice but can participate in diabetes under inflammatory conditions. Diabetes. 63: 3438-48. PMID 24812429 DOI: 10.2337/Db13-1882  0.443
2014 Calderon B, Carrero JA, Unanue ER. The central role of antigen presentation in islets of Langerhans in autoimmune diabetes. Current Opinion in Immunology. 26: 32-40. PMID 24556398 DOI: 10.1016/j.coi.2013.10.011  0.497
2014 Unanue ER. Antigen presentation in the autoimmune diabetes of the NOD mouse. Annual Review of Immunology. 32: 579-608. PMID 24499272 DOI: 10.1146/annurev-immunol-032712-095941  0.519
2013 Mohan JF, Calderon B, Anderson MS, Unanue ER. Pathogenic CD4⁺ T cells recognizing an unstable peptide of insulin are directly recruited into islets bypassing local lymph nodes. The Journal of Experimental Medicine. 210: 2403-14. PMID 24127484 DOI: 10.1084/Jem.20130582  0.811
2013 Yang CW, Unanue ER. Neutrophils control the magnitude and spread of the immune response in a thromboxane A2-mediated process. The Journal of Experimental Medicine. 210: 375-87. PMID 23337807 DOI: 10.1084/Jem.20122183  0.561
2013 Mohan JF, Unanue ER. A novel pathway of presentation by class II-MHC molecules involving peptides or denatured proteins important in autoimmunity. Molecular Immunology. 55: 166-8. PMID 23200226 DOI: 10.1016/J.Molimm.2012.10.024  0.837
2012 Mohan JF, Unanue ER. Unconventional recognition of peptides by T cells and the implications for autoimmunity. Nature Reviews. Immunology. 12: 721-8. PMID 22955843 DOI: 10.1038/Nri3294  0.835
2012 Carrero JA, Vivanco-Cid H, Unanue ER. Listeriolysin o is strongly immunogenic independently of its cytotoxic activity. Plos One. 7: e32310. PMID 22403645 DOI: 10.1371/journal.pone.0032310  0.404
2012 Ireland JM, Unanue ER. Processing of proteins in autophagy vesicles of antigen-presenting cells generates citrullinated peptides recognized by the immune system. Autophagy. 8: 429-30. PMID 22361580 DOI: 10.4161/auto.19261  0.496
2012 Calderon B, Unanue ER. Antigen presentation events in autoimmune diabetes. Current Opinion in Immunology. 24: 119-28. PMID 22178549 DOI: 10.1016/j.coi.2011.11.005  0.352
2011 Ireland JM, Unanue ER. Autophagy in antigen-presenting cells results in presentation of citrullinated peptides to CD4 T cells. The Journal of Experimental Medicine. 208: 2625-32. PMID 22162830 DOI: 10.1084/jem.20110640  0.482
2011 Edelson BT, Bradstreet TR, KC W, Hildner K, Herzog JW, Sim J, Russell JH, Murphy TL, Unanue ER, Murphy KM. Batf3-dependent CD11b(low/-) peripheral dendritic cells are GM-CSF-independent and are not required for Th cell priming after subcutaneous immunization. Plos One. 6: e25660. PMID 22065991 DOI: 10.1182/Blood.V118.21.1113.1113  0.691
2011 Mohan JF, Petzold SJ, Unanue ER. Register shifting of an insulin peptide-MHC complex allows diabetogenic T cells to escape thymic deletion. The Journal of Experimental Medicine. 208: 2375-83. PMID 22065673 DOI: 10.1084/Jem.20111502  0.828
2011 Edelson BT, Bradstreet TR, Hildner K, Carrero JA, Frederick KE, KC W, Belizaire R, Aoshi T, Schreiber RD, Miller MJ, Murphy TL, Unanue ER, Murphy KM. CD8α(+) dendritic cells are an obligate cellular entry point for productive infection by Listeria monocytogenes. Immunity. 35: 236-48. PMID 21867927 DOI: 10.1016/J.Immuni.2011.06.012  0.79
2011 Strong BS, Unanue ER. Presentation of type B peptide-MHC complexes from hen egg white lysozyme by TLR ligands and type I IFNs independent of H2-DM regulation. Journal of Immunology (Baltimore, Md. : 1950). 187: 2193-201. PMID 21788443 DOI: 10.4049/jimmunol.1100152  0.797
2011 Calderon B, Carrero JA, Miller MJ, Unanue ER. Cellular and molecular events in the localization of diabetogenic T cells to islets of Langerhans. Proceedings of the National Academy of Sciences of the United States of America. 108: 1561-6. PMID 21220322 DOI: 10.1073/pnas.1018973108  0.449
2011 Calderon B, Carrero JA, Miller MJ, Unanue ER. Entry of diabetogenic T cells into islets induces changes that lead to amplification of the cellular response. Proceedings of the National Academy of Sciences of the United States of America. 108: 1567-72. PMID 21220309 DOI: 10.1073/pnas.1018975108  0.402
2011 Atibalentja DF, Murphy KM, Unanue ER. Functional redundancy between thymic CD8α+ and Sirpα+ conventional dendritic cells in presentation of blood-derived lysozyme by MHC class II proteins. Journal of Immunology (Baltimore, Md. : 1950). 186: 1421-31. PMID 21178002 DOI: 10.4049/Jimmunol.1002587  0.813
2010 Yang CW, Strong BS, Miller MJ, Unanue ER. Neutrophils influence the level of antigen presentation during the immune response to protein antigens in adjuvants. Journal of Immunology (Baltimore, Md. : 1950). 185: 2927-34. PMID 20679530 DOI: 10.4049/Jimmunol.1001289  0.812
2010 Mohan JF, Levisetti MG, Calderon B, Herzog JW, Petzold SJ, Unanue ER. Unique autoreactive T cells recognize insulin peptides generated within the islets of Langerhans in autoimmune diabetes. Nature Immunology. 11: 350-4. PMID 20190756 DOI: 10.1038/Ni.1850  0.812
2010 Ise W, Kohyama M, Nutsch KM, Lee HM, Suri A, Unanue ER, Murphy TL, Murphy KM. CTLA-4 suppresses the pathogenicity of self antigen-specific T cells by cell-intrinsic and cell-extrinsic mechanisms. Nature Immunology. 11: 129-35. PMID 20037585 DOI: 10.1038/Ni.1835  0.634
2010 Unanue E. The unsolved mysteries of antigen presentation (ML14) International Immunology. 22: v1-v1. DOI: 10.1093/Intimm/Dxq223  0.308
2009 Atibalentja DF, Byersdorfer CA, Unanue ER. Thymus-blood protein interactions are highly effective in negative selection and regulatory T cell induction. Journal of Immunology (Baltimore, Md. : 1950). 183: 7909-18. PMID 19933868 DOI: 10.4049/Jimmunol.0902632  0.821
2009 Belizaire R, Unanue ER. Targeting proteins to distinct subcellular compartments reveals unique requirements for MHC class I and II presentation. Proceedings of the National Academy of Sciences of the United States of America. 106: 17463-8. PMID 19805168 DOI: 10.1073/Pnas.0908583106  0.736
2009 Chang KY, Unanue ER. Prediction of HLA-DQ8beta cell peptidome using a computational program and its relationship to autoreactive T cells. International Immunology. 21: 705-13. PMID 19461125 DOI: 10.1093/Intimm/Dxp039  0.705
2008 Hildner K, Edelson BT, Purtha WE, Diamond M, Matsushita H, Kohyama M, Calderon B, Schraml BU, Unanue ER, Diamond MS, Schreiber RD, Murphy TL, Murphy KM. Batf3 deficiency reveals a critical role for CD8alpha+ dendritic cells in cytotoxic T cell immunity. Science (New York, N.Y.). 322: 1097-100. PMID 19008445 DOI: 10.1126/Science.1164206  0.708
2008 Calderon B, Suri A, Pan XO, Mills JC, Unanue ER. IFN-gamma-dependent regulatory circuits in immune inflammation highlighted in diabetes. Journal of Immunology (Baltimore, Md. : 1950). 181: 6964-74. PMID 18981116 DOI: 10.4049/Jimmunol.181.10.6964  0.618
2008 Calderon B, Suri A, Miller MJ, Unanue ER. Dendritic cells in islets of Langerhans constitutively present beta cell-derived peptides bound to their class II MHC molecules. Proceedings of the National Academy of Sciences of the United States of America. 105: 6121-6. PMID 18427107 DOI: 10.1073/Pnas.0801973105  0.653
2008 Levisetti MG, Lewis DM, Suri A, Unanue ER. Weak proinsulin peptide-major histocompatibility complexes are targeted in autoimmune diabetes in mice. Diabetes. 57: 1852-60. PMID 18398138 DOI: 10.2337/Db08-0068  0.714
2008 Suri A, Walters JJ, Rohrs HW, Gross ML, Unanue ER. First signature of islet beta-cell-derived naturally processed peptides selected by diabetogenic class II MHC molecules. Journal of Immunology (Baltimore, Md. : 1950). 180: 3849-56. PMID 18322192 DOI: 10.4049/Jimmunol.180.6.3849  0.72
2008 Suri A, Levisetti MG, Unanue ER. Do the peptide-binding properties of diabetogenic class II molecules explain autoreactivity? Current Opinion in Immunology. 20: 105-10. PMID 18082388 DOI: 10.1016/J.Coi.2007.10.007  0.671
2007 Levisetti MG, Suri A, Petzold SJ, Unanue ER. The insulin-specific T cells of nonobese diabetic mice recognize a weak MHC-binding segment in more than one form. Journal of Immunology (Baltimore, Md. : 1950). 178: 6051-7. PMID 17475829 DOI: 10.4049/Jimmunol.178.10.6051  0.674
2007 Chang KY, Suri A, Unanue ER. Predicting peptides bound to I-Ag7 class II histocompatibility molecules using a novel expectation-maximization alignment algorithm. Proteomics. 7: 367-77. PMID 17211830 DOI: 10.1002/Pmic.200600584  0.728
2007 Lovitch SB, Esparza TJ, Schweitzer G, Herzog J, Unanue ER. Activation of type B T cells after protein immunization reveals novel pathways of in vivo presentation of peptides. Journal of Immunology (Baltimore, Md. : 1950). 178: 122-33. PMID 17182547 DOI: 10.4049/Jimmunol.178.1.122  0.795
2006 Calderon B, Suri A, Unanue ER. In CD4+ T-cell-induced diabetes, macrophages are the final effector cells that mediate islet beta-cell killing: studies from an acute model. The American Journal of Pathology. 169: 2137-47. PMID 17148676 DOI: 10.2353/Ajpath.2006.060539  0.617
2006 Unanue ER. From antigen processing to peptide-MHC binding. Nature Immunology. 7: 1277-9. PMID 17110945 DOI: 10.1038/ni1206-1277  0.422
2006 Ireland J, Herzog J, Unanue ER. Cutting edge: unique T cells that recognize citrullinated peptides are a feature of protein immunization. Journal of Immunology (Baltimore, Md. : 1950). 177: 1421-5. PMID 16849447  0.499
2006 Suri A, Calderon B, Esparza TJ, Frederick K, Bittner P, Unanue ER. Immunological reversal of autoimmune diabetes without hematopoietic replacement of beta cells. Science (New York, N.Y.). 311: 1778-80. PMID 16556846 DOI: 10.1126/Science.1123500  0.539
2006 Lovitch SB, Pu Z, Unanue ER. Amino-terminal flanking residues determine the conformation of a peptide-class II MHC complex. Journal of Immunology (Baltimore, Md. : 1950). 176: 2958-68. PMID 16493054 DOI: 10.4049/Jimmunol.176.5.2958  0.76
2006 Suri A, Walters JJ, Levisetti MG, Gross ML, Unanue ER. Identification of naturally processed peptides bound to the class I MHC molecule H-2Kd of normal and TAP-deficient cells. European Journal of Immunology. 36: 544-57. PMID 16479539 DOI: 10.1002/Eji.200526235  0.649
2006 Suri A, Lovitch SB, Unanue ER. The wide diversity and complexity of peptides bound to class II MHC molecules. Current Opinion in Immunology. 18: 70-7. PMID 16316750 DOI: 10.1016/J.Coi.2005.11.002  0.805
2006 Suri A, Unanue ER. Response to Comment on Suri et al. on Diabetes Reversal in NOD Mice Science. 314: 1243d-1243d. DOI: 10.1126/Science.1129917  0.511
2006 Levisetti M, Suri A, Petzold S, Unanue E. Su.32. Insulin-Specific T-Cells in Nod Mice: Evidence for Recognition of the Dominant Epitope in Two Distinct Binding Registers Clinical Immunology. 119: S170. DOI: 10.1016/J.Clim.2006.04.459  0.638
2005 Suri A, Unanue ER. The murine diabetogenic class II histocompatibility molecule I-Ag7: structural and functional properties and specificity of peptide selection. Advances in Immunology. 88: 235-65. PMID 16227092 DOI: 10.1016/S0065-2776(05)88007-1  0.627
2005 Lovitch SB, Unanue ER. Conformational isomers of a peptide-class II major histocompatibility complex. Immunological Reviews. 207: 293-313. PMID 16181344 DOI: 10.1111/J.0105-2896.2005.00298.X  0.792
2005 Byersdorfer CA, Schweitzer GG, Unanue ER. Diabetes is predicted by the beta cell level of autoantigen. Journal of Immunology (Baltimore, Md. : 1950). 175: 4347-54. PMID 16177075 DOI: 10.4049/Jimmunol.175.7.4347  0.673
2005 Babbitt BP, Allen PM, Matsueda G, Haber E, Unanue ER. Binding of immunogenic peptides to Ia histocompatibility molecules. 1985. Journal of Immunology (Baltimore, Md. : 1950). 175: 4163-5. PMID 16177052  0.344
2005 Unanue E, Byersdorfer C, Carrero J, Levisetti M, Lovitch S, Pu Z, Suri A. Antigen presentation: lysoyme, autoimmune diabetes, and Listeria--what do they have in common? Immunologic Research. 32: 267-92. PMID 16106079 DOI: 10.1385/Ir:32:1-3:267  0.84
2005 Suri A, Walters JJ, Gross ML, Unanue ER. Natural peptides selected by diabetogenic DQ8 and murine I-A(g7) molecules show common sequence specificity. The Journal of Clinical Investigation. 115: 2268-76. PMID 16075062 DOI: 10.1172/Jci25350  0.642
2005 Herzog J, Maekawa Y, Cirrito TP, Illian BS, Unanue ER. Activated antigen-presenting cells select and present chemically modified peptides recognized by unique CD4 T cells. Proceedings of the National Academy of Sciences of the United States of America. 102: 7928-33. PMID 15901898 DOI: 10.1073/Pnas.0502255102  0.857
2004 Levisetti MG, Suri A, Frederick K, Unanue ER. Absence of lymph nodes in NOD mice treated with lymphotoxin-beta receptor immunoglobulin protects from diabetes. Diabetes. 53: 3115-9. PMID 15561941 DOI: 10.2337/Diabetes.53.12.3115  0.559
2004 Byersdorfer CA, Dipaolo RJ, Petzold SJ, Unanue ER. Following immunization antigen becomes concentrated in a limited number of APCs including B cells. Journal of Immunology (Baltimore, Md. : 1950). 173: 6627-34. PMID 15557153 DOI: 10.4049/Jimmunol.173.11.6627  0.765
2004 Pu Z, Lovitch SB, Bikoff EK, Unanue ER. T cells distinguish MHC-peptide complexes formed in separate vesicles and edited by H2-DM. Immunity. 20: 467-76. PMID 15084275 DOI: 10.1016/S1074-7613(04)00073-1  0.779
2004 Suri A, Shimizu J, Katz JD, Sakaguchi S, Unanue ER, Kanagawa O. Regulation of autoimmune diabetes by non-islet-specific T cells - a role for the glucocorticoid-induced TNF receptor. European Journal of Immunology. 34: 447-54. PMID 14768049 DOI: 10.1002/Eji.200324599  0.626
2003 Levisetti MG, Suri A, Vidavsky I, Gross ML, Kanagawa O, Unanue ER. Autoantibodies and CD4 T cells target a beta cell retroviral envelope protein in non-obese diabetic mice. International Immunology. 15: 1473-83. PMID 14645156 DOI: 10.1093/Intimm/Dxg143  0.624
2003 Mogemark M, Cirrito TP, Sjölin P, Unanue ER, Kihlberg J. Influence of saccharide size on the cellular immune response to glycopeptides. Organic & Biomolecular Chemistry. 1: 2063-9. PMID 12945896 DOI: 10.1039/B301747H  0.82
2003 Lovitch SB, Petzold SJ, Unanue ER. Cutting edge: H-2DM is responsible for the large differences in presentation among peptides selected by I-Ak during antigen processing. Journal of Immunology (Baltimore, Md. : 1950). 171: 2183-6. PMID 12928360 DOI: 10.4049/Jimmunol.171.5.2183  0.765
2003 Unanue ER. Intracellular pathogens and antigen presentation-new challenges with Legionella pneumophila. Immunity. 18: 722-4. PMID 12818153 DOI: 10.1016/S1074-7613(03)00145-6  0.358
2003 Veeraswamy RK, Cella M, Colonna M, Unanue ER. Dendritic cells process and present antigens across a range of maturation states. Journal of Immunology (Baltimore, Md. : 1950). 170: 5367-72. PMID 12759410  0.379
2003 Suri A, Walters JJ, Kanagawa O, Gross ML, Unanue ER. Specificity of peptide selection by antigen-presenting cells homozygous or heterozygous for expression of class II MHC molecules: The lack of competition. Proceedings of the National Academy of Sciences of the United States of America. 100: 5330-5. PMID 12682304 DOI: 10.1073/Pnas.0330859100  0.656
2003 Lovitch SB, Walters JJ, Gross ML, Unanue ER. APCs present A beta(k)-derived peptides that are autoantigenic to type B T cells. Journal of Immunology (Baltimore, Md. : 1950). 170: 4155-60. PMID 12682247 DOI: 10.4049/Jimmunol.170.8.4155  0.785
2003 Krug A, Veeraswamy R, Pekosz A, Kanagawa O, Unanue ER, Colonna M, Cella M. Interferon-producing cells fail to induce proliferation of naive T cells but can promote expansion and T helper 1 differentiation of antigen-experienced unpolarized T cells. The Journal of Experimental Medicine. 197: 899-906. PMID 12668648 DOI: 10.1084/Jem.20021091  0.425
2002 Edelson BT, Unanue ER. MyD88-dependent but Toll-like receptor 2-independent innate immunity to Listeria: no role for either in macrophage listericidal activity. Journal of Immunology (Baltimore, Md. : 1950). 169: 3869-75. PMID 12244184 DOI: 10.4049/Jimmunol.169.7.3869  0.647
2002 DiPaolo RJ, Unanue ER. Cutting edge: the relative distribution of T cells responding to chemically dominant or minor epitopes of lysozyme is not affected by CD40-CD40 ligand and B7-CD28-CTLA-4 costimulatory pathways. Journal of Immunology (Baltimore, Md. : 1950). 169: 2832-6. PMID 12218093 DOI: 10.4049/Jimmunol.169.6.2832  0.342
2002 Unanue ER. Perspective on antigen processing and presentation. Immunological Reviews. 185: 86-102. PMID 12190925 DOI: 10.1034/j.1600-065X.2002.18510.x  0.376
2002 Pu Z, Carrero JA, Unanue ER. Distinct recognition by two subsets of T cells of an MHC class II-peptide complex. Proceedings of the National Academy of Sciences of the United States of America. 99: 8844-9. PMID 12084929 DOI: 10.1073/pnas.092260499  0.512
2002 DiPaolo RJ, Unanue ER. Cutting edge: chemical dominance does not relate to immunodominance: studies of the CD4+ T cell response to a model antigen. Journal of Immunology (Baltimore, Md. : 1950). 169: 1-4. PMID 12077220 DOI: 10.4049/Jimmunol.169.1.1  0.488
2002 Velazquez C, Vidavsky I, van der Drift K, Gross ML, Unanue ER. Chemical identification of a low abundance lysozyme peptide family bound to I-Ak histocompatibility molecules. The Journal of Biological Chemistry. 277: 42514-22. PMID 12055186 DOI: 10.1074/Jbc.M202316200  0.433
2002 Suri A, Vidavsky I, van der Drift K, Kanagawa O, Gross ML, Unanue ER. In APCs, the autologous peptides selected by the diabetogenic I-Ag7 molecule are unique and determined by the amino acid changes in the P9 pocket. Journal of Immunology (Baltimore, Md. : 1950). 168: 1235-43. PMID 11801660 DOI: 10.4049/Jimmunol.168.3.1235  0.614
2001 DiPaolo RJ, Unanue ER. The level of peptide-MHC complex determines the susceptibility to autoimmune diabetes: studies in HEL transgenic mice. European Journal of Immunology. 31: 3453-9. PMID 11745364 DOI: 10.1002/1521-4141(200112)31:12<3453::Aid-Immu3453>3.0.Co;2-H  0.498
2001 Cirrito TP, Pu Z, Deck MB, Unanue ER. Deamidation of asparagine in a major histocompatibility complex-bound peptide affects T cell recognition but does not explain type B reactivity. The Journal of Experimental Medicine. 194: 1165-70. PMID 11602644 DOI: 10.1084/Jem.194.8.1165  0.814
2001 Edelson BT, Unanue ER. Intracellular antibody neutralizes Listeria growth. Immunity. 14: 503-12. PMID 11371353 DOI: 10.1016/S1074-7613(01)00139-X  0.623
2001 Peterson DA, DiPaolo RJ, Kanagawa O, Unanue ER. Cutting edge: a single MHC anchor residue alters the conformation of a peptide-MHC complex inducing T cells that survive negative selection. Journal of Immunology (Baltimore, Md. : 1950). 166: 5874-7. PMID 11342600 DOI: 10.4049/Jimmunol.166.10.5874  0.484
2001 Velazquez C, DiPaolo R, Unanue ER. Quantitation of lysozyme peptides bound to class II MHC molecules indicates very large differences in levels of presentation Journal of Immunology. 166: 5488-5494. PMID 11313387 DOI: 10.4049/Jimmunol.166.9.5488  0.468
2000 Latek RR, Petzold SJ, Unanue ER. Hindering auxiliary anchors are potent modulators of peptide binding and selection by I-Ak class II molecules. Proceedings of the National Academy of Sciences of the United States of America. 97: 11460-5. PMID 11016975 DOI: 10.1073/Pnas.210384197  0.812
2000 Gugasyan R, Velazquez C, Vidavsky I, Deck BM, van der Drift K, Gross ML, Unanue ER. Independent selection by I-Ak molecules of two epitopes found in tandem in an extended polypeptide antigen. Journal of Immunology (Baltimore, Md. : 1950). 165: 3206-13. PMID 10975836 DOI: 10.4049/Jimmunol.165.6.3206  0.362
2000 Edelson BT, Unanue ER. Immunity to Listeria infection. Current Opinion in Immunology. 12: 425-31. PMID 10899025 DOI: 10.1016/S0952-7915(00)00112-6  0.657
2000 Latek RR, Suri A, Petzold SJ, Nelson CA, Kanagawa O, Unanue ER, Fremont DH. Structural basis of peptide binding and presentation by the type I diabetes-associated MHC class II molecule of NOD mice. Immunity. 12: 699-710. PMID 10894169 DOI: 10.1016/S1074-7613(00)80220-4  0.815
1999 Latek RR, Unanue ER. Mechanisms and consequences of peptide selection by the I-Ak class II molecule. Immunological Reviews. 172: 209-28. PMID 10631948 DOI: 10.1111/J.1600-065X.1999.Tb01367.X  0.823
1999 Peterson DA, DiPaolo RJ, Kanagawa O, Unanue ER. Quantitative analysis of the T cell repertoire that escapes negative selection. Immunity. 11: 453-62. PMID 10549627 DOI: 10.1016/S1074-7613(00)80120-X  0.503
1999 Carrasco-Marín E, Petzold S, Unanue ER. Two structural states of complexes of peptide and class II major histocompatibility complex revealed by photoaffinity-labeled peptides. The Journal of Biological Chemistry. 274: 31333-40. PMID 10531333 DOI: 10.1074/jbc.274.44.31333  0.357
1999 Edelson BT, Cossart P, Unanue ER. Cutting edge: paradigm revisited: antibody provides resistance to Listeria infection. Journal of Immunology (Baltimore, Md. : 1950). 163: 4087-90. PMID 10510340  0.652
1999 Carrasco-Marin E, Kanagawa O, Unanue ER. The lack of consensus for I-A(g7)-peptide binding motifs: Is there a requirement for anchor amino acid side chains? Proceedings of the National Academy of Sciences of the United States of America. 96: 8621-8626. PMID 10411925 DOI: 10.1073/pnas.96.15.8621  0.407
1999 Unanue ER. Chemical features of peptide selection by the class II histocompatibility molecules American Journal of Pathology. 154: 651-664. PMID 10079241 DOI: 10.1016/S0002-9440(10)65311-4  0.416
1999 Teitelbaum R, Glatman-Freedman A, Chen B, Robbins JB, Unanue E, Casadevall A, Bloom BR. A mAb recognizing a surface antigen of Mycobacterium tuberculosis enhances host survival. Proceedings of the National Academy of Sciences of the United States of America. 95: 15688-93. PMID 9861031 DOI: 10.1073/Pnas.95.26.15688  0.344
1998 Fremont DH, Monnaie D, Nelson CA, Hendrickson WA, Unanue ER. Crystal structure of I-Ak in complex with a dominant epitope of lysozyme. Immunity. 8: 305-17. PMID 9529148 DOI: 10.1016/S1074-7613(00)80536-1  0.324
1998 Kanagawa O, Martin SM, Vaupel BA, Carrasco-Marin E, Unanue ER. Autoreactivity of T cells from nonobese diabetic mice: an I-Ag7-dependent reaction. Proceedings of the National Academy of Sciences of the United States of America. 95: 1721-4. PMID 9465083 DOI: 10.1073/pnas.95.4.1721  0.49
1997 Kanagawa O, Shimizu J, Unanue ER. The role of I-A(g7) β chain in peptide binding and antigen recognition by T cells International Immunology. 9: 1523-1526. PMID 9352357 DOI: 10.1093/intimm/9.10.1523  0.426
1997 Unanue ER. Studies in listeriosis show the strong symbiosis between the innate cellular system and the T-cell response Immunological Reviews. 158: 11-25. PMID 9314070 DOI: 10.1111/j.1600-065X.1997.tb00988.x  0.357
1997 Merrick JC, Edelson BT, Bhardwaj V, Swanson PE, Unanue ER. Lymphocyte apoptosis during early phase of Listeria infection in mice. The American Journal of Pathology. 151: 785-92. PMID 9284827  0.617
1997 Dadaglio G, Nelson CA, Deck MB, Petzold SJ, Unanue ER. Characterization and quantitation of peptide-MHC complexes produced from hen egg lysozyme using a monoclonal antibody. Immunity. 6: 727-38. PMID 9208845 DOI: 10.1016/S1074-7613(00)80448-3  0.468
1997 Dustin ML, Bromley SK, Kan Z, Peterson DA, Unanue ER. Antigen receptor engagement delivers a stop signal to migrating T lymphocytes. Proceedings of the National Academy of Sciences of the United States of America. 94: 3909-13. PMID 9108078 DOI: 10.1073/Pnas.94.8.3909  0.447
1997 Nelson CA, Vidavsky I, Viner NJ, Gross ML, Unanue ER. Amino-terminal trimming of peptides for presentation on major histocompatibility complex class II molecules. Proceedings of the National Academy of Sciences of the United States of America. 94: 628-33. PMID 9012835 DOI: 10.1073/Pnas.94.2.628  0.432
1997 Lindner R, Unanue E. Association of peptide and protein antigen with MHC class II on distinct processing pathways Immunobiology. 197: 159.  0.367
1996 Lindner R, Unanue ER. Distinct antigen MHC class II complexes generated by separate processing pathways Embo Journal. 15: 6910-6920. PMID 9003767  0.367
1996 Nelson CA, Viner NJ, Unanue ER. Appreciating the complexity of MHC class II peptide binding: lysozyme peptide and I-Ak. Immunological Reviews. 151: 81-105. PMID 8872486 DOI: 10.1111/j.1600-065X.1996.tb00704.x  0.377
1996 Lindner R, Unanue ER. Stable association of protein antigen with MHC class II in an HLA-DM-independent pathway Faseb Journal. 10.  0.338
1996 Carrasco-Marm E, Unanue ER. Analysis of the interaction of peptide-class II MHC molecule by photoaffinity labeling Faseb Journal. 10.  0.389
1995 Unanue ER. The Concept of Antigen Processing and Presentation Jama: the Journal of the American Medical Association. 274: 1071-1073. PMID 7563463 DOI: 10.1001/jama.1995.03530130077035  0.372
1995 Viner NJ, Nelson CA, Unanue ER. Identification of a major I-Ek-restricted determinant of hen egg lysozyme: limitations of lymph node proliferation studies in defining immunodominance and crypticity. Proceedings of the National Academy of Sciences of the United States of America. 92: 2214-8. PMID 7534415 DOI: 10.1073/pnas.92.6.2214  0.434
1994 Nelson CA, Petzold SJ, Unanue ER. Peptides determine the lifespan of MHC class II molecules in the antigen-presenting cell. Nature. 371: 250-2. PMID 8078585 DOI: 10.1038/371250a0  0.506
1993 Nelson CA, Petzold SJ, Unanue ER. Identification of two distinct properties of class II major histocompatibility complex-associated peptides. Proceedings of the National Academy of Sciences of the United States of America. 90: 1227-31. PMID 8433983 DOI: 10.1073/Pnas.90.4.1227  0.531
1993 Shimizu J, Kanagawa O, Unanue ER. Presentation of β-Cell antigens to CD4+ and CD8+ T cells of non-obese diabetic mice Journal of Immunology. 151: 1723-1730. PMID 8101546  0.392
1993 Corbett JA, Mikhael A, Shimizu J, Frederick K, Misko TP, Mcdaniel ML, Kanagawa O, Unanue ER. Nitric oxide production in islets from nonobese diabetic mice: Aminoguanidine-sensitive and -resistant stages in the immunological diabetic process Proceedings of the National Academy of Sciences of the United States of America. 90: 8992-8995. PMID 7692442 DOI: 10.1073/Pnas.90.19.8992  0.333
1992 Bancroft GJ, Schreiber RD, Unanue ER. Natural immunity: a T-cell-independent pathway of macrophage activation, defined in the scid mouse. Immunological Reviews. 124: 5-24. PMID 1804781 DOI: 10.1111/J.1600-065X.1991.Tb00613.X  0.32
1992 Unanue ER. Cellular studies on antigen presentation by class II MHC molecules Current Opinion in Immunology. 4: 63-69. PMID 1596369 DOI: 10.1016/0952-7915(92)90127-Z  0.311
1992 Rogers HW, Sheehan KCF, Brunt LM, Dower SK, Unanue ER, Schreiber RD. Interleukin 1 participates in the development of anti-Listeria responses in normal and SCID mice Proceedings of the National Academy of Sciences of the United States of America. 89: 1011-1015. PMID 1531270 DOI: 10.1073/Pnas.89.3.1011  0.344
1992 Nelson CA, Roof RW, McCourt DW, Unanue ER. Identification of the naturally processed form of hen egg white lysozyme bound to the murine major histocompatibility complex class II molecule I-Ak. Proceedings of the National Academy of Sciences of the United States of America. 89: 7380-3. PMID 1323833 DOI: 10.1073/pnas.89.16.7380  0.425
1991 Allen PM, Matsueda GR, Adams S, Freeman J, Roof RW, Lambert L, Unanue ER. Enhanced immunogenicity of a T cell immunogenic peptide by modifications of its N and C termini. International Immunology. 1: 141-50. PMID 2484881 DOI: 10.1093/intimm/1.2.141  0.436
1991 Hogquist KA, Nett MA, Unanue ER, Chaplin DD. Interleukin 1 is processed and released during apoptosis. Proceedings of the National Academy of Sciences of the United States of America. 88: 8485-9. PMID 1924307 DOI: 10.1073/Pnas.88.19.8485  0.652
1991 Hogquist KA, Unanue ER, Chaplin DD. Release of IL-1 from mononuclear phagocytes. Journal of Immunology (Baltimore, Md. : 1950). 147: 2181-6. PMID 1918954  0.6
1991 Harding CV, Collins DS, Slot JW, Geuze HJ, Unanue ER. Liposome-encapsulated antigens are processed in lysosomes, recycled, and presented to T cells. Cell. 64: 393-401. PMID 1899049 DOI: 10.1016/0092-8674(91)90647-H  0.416
1991 Harding CV, Unanue ER. Modulation of antigen presentation and peptide-MHC-specific, LFA-1-dependent T cell-macrophage adhesion Journal of Immunology. 147: 767-773. PMID 1861073  0.487
1990 Harding CV, Unanue ER, Slot JW, Schwartz AL, Geuze HJ. Functional and ultrastructural evidence for intracellular formation of major histocompatibility complex class II-peptide complexes during antigen processing. Proceedings of the National Academy of Sciences of the United States of America. 87: 5553-7. PMID 2371288 DOI: 10.1073/pnas.87.14.5553  0.377
1990 Roof RW, Luescher IF, Unanue ER. Phospholipids enhance the binding of peptides to class II major histocompatibility molecules. Proceedings of the National Academy of Sciences of the United States of America. 87: 1735-9. PMID 2308932 DOI: 10.1073/pnas.87.5.1735  0.312
1990 Weaver CT, Unanue ER. The costimulatory function of antigen-presenting cells Immunology Today. 11: 49-55. PMID 2185780 DOI: 10.1016/0167-5699(90)90018-5  0.386
1990 Harding CV, Unanue ER. Quantitation of antigen-presenting cell MHC class II/peptide complexes necessary for T-cell stimulation Nature. 346: 574-576. PMID 2115981 DOI: 10.1038/346574A0  0.491
1990 Harding CV, Unanue ER. Low-temperature inhibition of antigen processing and iron uptake from transferrin: Deficits in endosome functions at 18°C European Journal of Immunology. 20: 323-329. PMID 1968838 DOI: 10.1002/Eji.1830200214  0.335
1990 Weaver CT, Unanue ER. The costimulatory function of antigen-presenting cells Trends in Immunology. 11: 55-59.  0.386
1989 Harding CV, Leyva-Cobian F, Unanue ER. Mechanisms of antigen processing. Immunological Reviews. 106: 77-92. PMID 3075593 DOI: 10.1111/J.1600-065X.1988.Tb00774.X  0.377
1989 Lambert LE, Unanue ER. Analysis of the interaction of peptide hen egg white lysozyme (34-45) with the I-A(k) molecule Journal of Immunology. 143: 802-807. PMID 2787347  0.398
1989 Harding CV, Roof RW, Unanue ER. Turnover of Ia-peptide complexes is facilitated in viable antigen-presenting cells: biosynthetic turnover of Ia vs. peptide exchange. Proceedings of the National Academy of Sciences of the United States of America. 86: 4230-4. PMID 2786208 DOI: 10.1073/Pnas.86.11.4230  0.472
1989 Fuhlbrigge RC, Hogquist KA, Unanue ER, Chaplin DD. Molecular biology and genetics of interleukin-1. The Year in Immunology. 5: 21-37. PMID 2523623  0.57
1989 Bancroft GJ, Schreiber RD, Unanue ER. T cell-independent macrophage activation in scid mice Current Topics in Microbiology and Immunology. 152: 235-242. PMID 2509143 DOI: 10.1007/978-3-642-74974-2_28  0.323
1988 Luescher IF, Allen PM, Unanue ER. Binding of photoreactive lysozyme peptides to murine histocompatibility class II molecules. Proceedings of the National Academy of Sciences of the United States of America. 85: 871-4. PMID 3422468 DOI: 10.1073/pnas.85.3.871  0.321
1988 Fuhlbrigge RC, Fine SM, Unanue ER, Chaplin DD. Expression of membrane interleukin 1 by fibroblasts transfected with murine pro-interleukin 1α cDNA Proceedings of the National Academy of Sciences of the United States of America. 85: 5649-5653. PMID 3261013 DOI: 10.1073/pnas.85.15.5649  0.4
1988 Leyva-Cobian F, Unanue ER. Intracellular interference with antigen presentation Journal of Immunology. 141: 1445-1450. PMID 3137257  0.422
1988 Hawrylowicz CM, Unanue ER. Regulation of antigen-presentation-I. IFN-γ induces antigen-presenting properties on B cells Journal of Immunology. 141: 4083-4088. PMID 2974053  0.323
1988 Weaver CT, Hawrylowicz CM, Unanue ER. T helper cell subsets require the expression of distinct costimulatory signals by antigen-presenting cells Proceedings of the National Academy of Sciences of the United States of America. 85: 8181-8185. PMID 2973060 DOI: 10.1073/Pnas.85.21.8181  0.355
1987 Unanue ER, Weaver CT, Fuhlbrigge RC, Kiely JM, Chaplin DD. Membrane IL-1: A key protein in antigen presentation Annales De L'Institut Pasteur - Immunology. 138: 489-492. PMID 3498500 DOI: 10.1016/S0769-2625(87)80064-8  0.482
1987 Allen PM, Babbitt BP, Unanue ER. T-cell recognition of lysozyme: the biochemical basis of presentation. Immunological Reviews. 98: 171-87. PMID 2443441 DOI: 10.1111/j.1600-065X.1987.tb00524.x  0.334
1987 Allen PM, Matsueda GR, Evans RJ, Dunbar JB, Marshall GR, Unanue ER. Identification of the T-cell and Ia contact residues of a T-cell antigenic epitope. Nature. 327: 713-5. PMID 2439915 DOI: 10.1038/327713A0  0.483
1986 Babbitt BP, Matsueda G, Haber E, Unanue ER, Allen PM. Antigenic competition at the level of peptide-Ia binding. Proceedings of the National Academy of Sciences of the United States of America. 83: 4509-13. PMID 3459185 DOI: 10.1073/Pnas.83.12.4509  0.416
1986 Unanue ER, Allen PM. Biochemistry and biology of antigen presentation by macrophages Cellular Immunology. 99: 3-6. PMID 3093102 DOI: 10.1016/0008-8749(86)90208-X  0.41
1986 Weaver CT, Unanue ER. T cell induction of membrane IL 1 on macrophages Journal of Immunology. 137: 3868-3873. PMID 2946770  0.389
1985 Babbitt BP, Allen PM, Matsueda G, Haber E, Unanue ER. Binding of immunogenic peptides to Ia histocompatibility molecules. Nature. 317: 359-61. PMID 3876513 DOI: 10.1038/317359A0  0.503
1985 Allen P, Matsueda G, Haber E, Unanue E. Fine structure analysis of the determinants being recognized by two HEL-specific T cell hybridomas Federation Proceedings. 44.  0.302
1984 Allen PM, Unanue ER. Antigen processing and presentation by macrophages American Journal of Anatomy. 170: 483-490. PMID 6433692 DOI: 10.1002/aja.1001700319  0.441
1984 Unanue ER. Antigen-presenting function of the macrophage Annual Review of Immunology. 2: 395-428. PMID 6242349  0.432
1984 Allen PM, Strydom DJ, Unanue ER. Processing of lysozyme by macrophages: identification of the determinant recognized by two T-cell hybridomas. Proceedings of the National Academy of Sciences of the United States of America. 81: 2489-93. PMID 6201858 DOI: 10.1073/pnas.81.8.2489  0.446
1982 Ziegler HK, Unanue ER. Decrease in macrophage antigen catabolism caused by ammonia and chloroquine is associated with inhibition of antigen presentation to T cells Proceedings of the National Academy of Sciences of the United States of America. 79: 175-178. PMID 6798568  0.337
1982 Lu CY, Unanue ER. Spontaneous T-cell lymphokine production and enhanced macrophage la expression and tumoricidal acitivity in MRL-Ipr mice Clinical Immunology and Immunopathology. 25: 213-222. PMID 6762274 DOI: 10.1016/0090-1229(82)90184-2  0.317
1980 Beller DI, Unanue ER. Ia antigens and antigen-presenting function of thymic macrophages Journal of Immunology. 124: 1433-1440. PMID 7358986  0.326
1980 Kammer GM, Unanue ER. Accessory cell requirement in the proliferative response of T lymphocytes to hemocyanin Clinical Immunology and Immunopathology. 15: 434-443. PMID 6966200 DOI: 10.1016/0090-1229(80)90055-0  0.357
1980 Lu CY, Beller DI, Unanue ER. During ontogeny, Ia-bearing accessory cells are found early in the thymus but late in the spleen. Proceedings of the National Academy of Sciences of the United States of America. 77: 1597-601. PMID 6929512 DOI: 10.1073/pnas.77.3.1597  0.369
1980 Unanue ER. Cooperation between mononuclear phagocytes and lymphocytes in immunity New England Journal of Medicine. 303: 977-985. PMID 6774253  0.327
1979 Unanue ER. The macrophage as a regulator of lymphocyte function Hospital Practice. 14: 61-74. PMID 315360  0.359
1979 Ziegler K, Unanue ER. The specific binding of Listeria monocytogenes-immune T lymphocytes to macrophages. I. Quantitation and role of H-2 gene products Journal of Experimental Medicine. 150: 1143-1160. PMID 115958  0.325
1977 Farr AG, Dorf ME, Unanue ER. Secretion of mediators following T lymphocyte-macrophage interaction is regulated by the major histocompatibility complex. Proceedings of the National Academy of Sciences of the United States of America. 74: 3542-6. PMID 410022 DOI: 10.1073/pnas.74.8.3542  0.353
1976 Unanue ER, Kiely JM, Calderon J. The modulation of lymphocyte functions by molecules secreted by macrophages. II. Conditions leading to increased secretion. The Journal of Experimental Medicine. 144: 155-66. PMID 1084402 DOI: 10.1084/jem.144.1.155  0.307
1975 Calderon J, Kiely JM, Lefko JL, Unanue ER. The modulation of lymphocyte functions by molecules secreted by macrophages. I. Description and partial biochemical analysis. The Journal of Experimental Medicine. 142: 151-64. PMID 1097572 DOI: 10.1084/jem.142.1.151  0.324
1974 Engers HD, Unanue ER. Antigen binding thymic lymphocytes: Specific binding of soluble antigen molecules and quantitation of surface receptor sites Journal of Immunology. 112: 293-304. PMID 4130149  0.328
1973 Unanue ER, Katz DH. Immunogenicity of macrophage bound antigens: the requirement for hapten and carrier determinants to be on the same molecule for T and B lymphocyte collaboration European Journal of Immunology. 3: 559-563. PMID 4128975  0.321
1972 Dunham EK, Unanue ER, Benacerraf B. Antigen binding and capping by lymphocytes of genetic nonresponder mice. The Journal of Experimental Medicine. 136: 403-8. PMID 5043419 DOI: 10.1084/Jem.136.2.403  0.325
1972 Lane FC, Unanue ER. Requirement of thymus (T) lymphocytes for resistance to listeriosis Journal of Experimental Medicine. 135: 1104-1112. PMID 4623315 DOI: 10.1084/Jem.135.5.1104  0.398
1968 Unanue ER, Askonas BA. Persistence of immunogenicity of antigen after uptake by macrophages Journal of Experimental Medicine. 127: 915-926. PMID 5655102 DOI: 10.1084/Jem.127.5.915  0.31
Show low-probability matches.