Guilian Xu, Ph.D. - Publications

Affiliations: 
Neuroscience University of Florida, Gainesville, Gainesville, FL, United States 
Area:
transgenic mice, Alzheimer's disease, ALS,
Website:
http://neuroscience.ufl.edu/faculty-and-staff-directory/faculty/guilian-xu-ph-d/

69/110 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2023 Ayers JI, Xu G, Lu Q, Dillon K, Fromholt S, Borchelt DR. Multiple Factors Influence the Incubation Period of ALS Prion-like Transmission in SOD1 Transgenic Mice. Viruses. 15. PMID 37766226 DOI: 10.3390/v15091819  0.539
2022 Xu G, Fromholt S, Borchelt DR. Modeling the Competition between Misfolded Aβ Conformers That Produce Distinct Types of Amyloid Pathology in Alzheimer's Disease. Biomolecules. 12. PMID 35883442 DOI: 10.3390/biom12070886  0.579
2022 Xia Y, Prokop S, Bell BM, Gorion KM, Croft CL, Nasif L, Xu G, Riffe CJ, Manaois AN, Strang KH, Quintin SS, Paterno G, Tansey MG, Borchelt DR, Golde TE, et al. Pathogenic tau recruits wild-type tau into brain inclusions and induces gut degeneration in transgenic SPAM mice. Communications Biology. 5: 446. PMID 35550593 DOI: 10.1038/s42003-022-03373-1  0.587
2022 Moore BD, Levites Y, Xu G, Hampton H, Adamo MF, Croft CL, Futch HS, Moran C, Fromholt S, Janus C, Prokop S, Dickson D, Lewis J, Giasson BI, Golde TE, et al. Soluble brain homogenates from diverse human and mouse sources preferentially seed diffuse Aβ plaque pathology when injected into newborn mouse hosts. Free Neuropathology. 3. PMID 35494163 DOI: 10.17879/freeneuropathology-2022-3766  0.596
2022 Williams T, Ruiz AJ, Ruiz AM, Vo Q, Tsering W, Xu G, McFarland K, Giasson BI, Sullivan P, Borchelt DR, Chakrabarty P. Impact of APOE genotype on prion-type propagation of tauopathy. Acta Neuropathologica Communications. 10: 57. PMID 35440098 DOI: 10.1186/s40478-022-01359-y  0.593
2022 Xu G, Ulm BS, Howard J, Fromholt SE, Lu Q, Lee BB, Walker A, Borchelt DR, Lewis J. TAPPing into the potential of inducible tau/APP transgenic mice. Neuropathology and Applied Neurobiology. PMID 35067965 DOI: 10.1111/nan.12791  0.606
2021 Koller EJ, Ibanez KR, Vo Q, McFarland KN, Gonzalez De La Cruz E, Zobel L, Williams T, Xu G, Ryu D, Patel P, Giasson BI, Prokop S, Chakrabarty P. Combinatorial model of amyloid β and tau reveals synergy between amyloid deposits and tangle formation. Neuropathology and Applied Neurobiology. PMID 34825397 DOI: 10.1111/nan.12779  0.33
2021 Ayers JI, Xu G, Dillon K, Lu Q, Chen Z, Beckman J, Moreno-Romero AK, Zamora DL, Galaleldeen A, Borchelt DR. Variation in the vulnerability of mice expressing human superoxide dismutase 1 to prion-like seeding: a study of the influence of primary amino acid sequence. Acta Neuropathologica Communications. 9: 92. PMID 34016165 DOI: 10.1186/s40478-021-01191-w  0.555
2021 Xia Y, Chen Z, Xu G, Borchelt DR, Ayers JI, Giasson BI. Novel SOD1 monoclonal antibodies against the electrostatic loop preferentially detect misfolded SOD1 aggregates. Neuroscience Letters. 742: 135553. PMID 33346076 DOI: 10.1016/j.neulet.2020.135553  0.504
2020 Xu G, Fromholt SE, Chakrabarty P, Zhu F, Liu X, Pace MC, Koh J, Golde TE, Levites Y, Lewis J, Borchelt DR. Diversity in Aβ deposit morphology and secondary proteome insolubility across models of Alzheimer-type amyloidosis. Acta Neuropathologica Communications. 8: 43. PMID 32252825 DOI: 10.1186/S40478-020-00911-Y  0.65
2018 De Rossi P, Andrew RJ, Musial TF, Buggia-Prevot V, Xu G, Ponnusamy M, Ly H, Krause SV, Rice RC, de l'Estoile V, Valin T, Salem S, Despa F, Borchelt DR, Bindokas VP, et al. Aberrant accrual of BIN1 near Alzheimer's disease amyloid deposits in transgenic models. Brain Pathology (Zurich, Switzerland). PMID 30506549 DOI: 10.1111/Bpa.12687  0.637
2018 Pace MC, Xu G, Fromholt S, Howard J, Crosby K, Giasson BI, Lewis J, Borchelt DR. Changes in proteome solubility indicate widespread proteostatic disruption in mouse models of neurodegenerative disease. Acta Neuropathologica. PMID 30140941 DOI: 10.1007/S00401-018-1895-Y  0.634
2018 Pace MC, Xu G, Fromholt S, Howard J, Giasson BI, Lewis J, Borchelt DR. Differential induction of mutant SOD1 misfolding and aggregation by tau and α-synuclein pathology. Molecular Neurodegeneration. 13: 23. PMID 29776378 DOI: 10.1186/S13024-018-0253-9  0.596
2018 Iradi MCG, Triplett JC, Thomas JD, Davila R, Crown AM, Brown H, Lewis J, Swanson MS, Xu G, Rodriguez-Lebron E, Borchelt DR. Characterization of gene regulation and protein interaction networks for Matrin 3 encoding mutations linked to amyotrophic lateral sclerosis and myopathy. Scientific Reports. 8: 4049. PMID 29511296 DOI: 10.1038/S41598-018-21371-4  0.557
2016 Xu G, Pattamatta A, Hildago R, Pace MC, Brown H, Borchelt DR. Vulnerability of newly synthesized proteins to proteostasis stress. Journal of Cell Science. 129: 1892-901. PMID 27026526 DOI: 10.1242/Jcs.176479  0.53
2015 Xu G, Ran Y, Fromholt SE, Fu C, Yachnis AT, Golde TE, Borchelt DR. Murine Aβ over-production produces diffuse and compact Alzheimer-type amyloid deposits. Acta Neuropathologica Communications. 3: 72. PMID 26566997 DOI: 10.1186/S40478-015-0252-9  0.668
2015 Janus C, Flores AY, Xu G, Borchelt DR. Behavioral abnormalities in APPSwe/PS1dE9 mouse model of AD-like pathology: comparative analysis across multiple behavioral domains. Neurobiology of Aging. 36: 2519-32. PMID 26089165 DOI: 10.1016/J.Neurobiolaging.2015.05.010  0.574
2015 Li Z, Gu TP, Weber AR, Shen JZ, Li BZ, Xie ZG, Yin R, Guo F, Liu X, Tang F, Wang H, Schär P, Xu GL. Gadd45a promotes DNA demethylation through TDG. Nucleic Acids Research. 43: 3986-97. PMID 25845601 DOI: 10.1093/Nar/Gkv283  0.541
2015 Xu G, Fromholt S, Ayers JI, Brown H, Siemienski Z, Crosby KW, Mayer CA, Janus C, Borchelt DR. Substantially elevating the levels of αB-crystallin in spinal motor neurons of mutant SOD1 mice does not significantly delay paralysis or attenuate mutant protein aggregation. Journal of Neurochemistry. 133: 452-64. PMID 25557022 DOI: 10.1111/Jnc.13022  0.63
2015 Xu G, Ayers JI, Roberts BL, Brown H, Fromholt S, Green C, Borchelt DR. Direct and indirect mechanisms for wild-type SOD1 to enhance the toxicity of mutant SOD1 in bigenic transgenic mice. Human Molecular Genetics. 24: 1019-35. PMID 25305079 DOI: 10.1093/Hmg/Ddu517  0.625
2014 Ayers JI, Fromholt S, Koch M, DeBosier A, McMahon B, Xu G, Borchelt DR. Experimental transmissibility of mutant SOD1 motor neuron disease. Acta Neuropathologica. 128: 791-803. PMID 25262000 DOI: 10.1007/S00401-014-1342-7  0.622
2014 Guo F, Li X, Liang D, Li T, Zhu P, Guo H, Wu X, Wen L, Gu TP, Hu B, Walsh CP, Li J, Tang F, Xu GL. Active and passive demethylation of male and female pronuclear DNA in the mammalian zygote. Cell Stem Cell. 15: 447-58. PMID 25220291 DOI: 10.1016/j.stem.2014.08.003  0.524
2014 Tebbenkamp AT, Xu G, Siemienski ZB, Janus C, Fromholt SE, Brown HH, Swing D, Tessarollo L, Borchelt DR. Experimental mutagenesis of huntingtin to map cleavage sites: different outcomes in cell and mouse models. Journal of Huntington's Disease. 3: 73-86. PMID 25062766 DOI: 10.3233/Jhd-130087  0.762
2014 Ayers JI, Xu G, Pletnikova O, Troncoso JC, Hart PJ, Borchelt DR. Conformational specificity of the C4F6 SOD1 antibody; low frequency of reactivity in sporadic ALS cases. Acta Neuropathologica Communications. 2: 55. PMID 24887207 DOI: 10.1186/2051-5960-2-55  0.543
2014 Hu X, Zhang L, Mao SQ, Li Z, Chen J, Zhang RR, Wu HP, Gao J, Guo F, Liu W, Xu GF, Dai HQ, Shi YG, Li X, Hu B, ... ... Xu GL, et al. Tet and TDG mediate DNA demethylation essential for mesenchymal-to-epithelial transition in somatic cell reprogramming. Cell Stem Cell. 14: 512-22. PMID 24529596 DOI: 10.1016/J.Stem.2014.01.001  0.537
2013 Kam RK, Shi W, Chan SO, Chen Y, Xu G, Lau CB, Fung KP, Chan WY, Zhao H. Dhrs3 protein attenuates retinoic acid signaling and is required for early embryonic patterning. The Journal of Biological Chemistry. 288: 31477-87. PMID 24045938 DOI: 10.1074/Jbc.M113.514984  0.578
2013 Rutherford NJ, Lewis J, Clippinger AK, Thomas MA, Adamson J, Cruz PE, Cannon A, Xu G, Golde TE, Shaw G, Borchelt DR, Giasson BI. Unbiased screen reveals ubiquilin-1 and -2 highly associated with huntingtin inclusions. Brain Research. 1524: 62-73. PMID 23774650 DOI: 10.1016/J.Brainres.2013.06.006  0.612
2013 Zhang RR, Cui QY, Murai K, Lim YC, Smith ZD, Jin S, Ye P, Rosa L, Lee YK, Wu HP, Liu W, Xu ZM, Yang L, Ding YQ, Tang F, ... ... Xu GL, et al. Tet1 regulates adult hippocampal neurogenesis and cognition. Cell Stem Cell. 13: 237-45. PMID 23770080 DOI: 10.1016/J.Stem.2013.05.006  0.566
2013 Price AR, Xu G, Siemienski ZB, Smithson LA, Borchelt DR, Golde TE, Felsenstein KM. Comment on "ApoE-directed therapeutics rapidly clear β-amyloid and reverse deficits in AD mouse models". Science (New York, N.Y.). 340: 924-d. PMID 23704553 DOI: 10.1126/science.1234089  0.558
2013 Clippinger AK, D'Alton S, Lin WL, Gendron TF, Howard J, Borchelt DR, Cannon A, Carlomagno Y, Chakrabarty P, Cook C, Golde TE, Levites Y, Ranum L, Schultheis PJ, Xu G, et al. Robust cytoplasmic accumulation of phosphorylated TDP-43 in transgenic models of tauopathy. Acta Neuropathologica. 126: 39-50. PMID 23666556 DOI: 10.1007/S00401-013-1123-8  0.631
2013 Xu G, Stevens SM, Moore BD, McClung S, Borchelt DR. Cytosolic proteins lose solubility as amyloid deposits in a transgenic mouse model of Alzheimer-type amyloidosis. Human Molecular Genetics. 22: 2765-74. PMID 23512986 DOI: 10.1093/Hmg/Ddt121  0.662
2013 Melnikova T, Fromholt S, Kim H, Lee D, Xu G, Price A, Moore BD, Golde TE, Felsenstein KM, Savonenko A, Borchelt DR. Reversible pathologic and cognitive phenotypes in an inducible model of Alzheimer-amyloidosis. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 33: 3765-79. PMID 23447589 DOI: 10.1523/Jneurosci.4251-12.2013  0.625
2012 Xu G, Stevens SM, Kobeissy F, Kobiessy F, Brown H, McClung S, Gold MS, Borchelt DR. Identification of proteins sensitive to thermal stress in human neuroblastoma and glioma cell lines. Plos One. 7: e49021. PMID 23145051 DOI: 10.1371/Journal.Pone.0049021  0.512
2012 Guo L, Liu K, Xu G, Li X, Tu J, Tang F, Xing Y, Xi T. Prophylactic and therapeutic efficacy of the epitope vaccine CTB-UA against Helicobacter pylori infection in a BALB/c mice model. Applied Microbiology and Biotechnology. 95: 1437-44. PMID 22569640 DOI: 10.1007/s00253-012-4122-0  0.521
2012 Xu G, Green CC, Fromholt SE, Borchelt DR. Reduction of low-density lipoprotein receptor-related protein (LRP1) in hippocampal neurons does not proportionately reduce, or otherwise alter, amyloid deposition in APPswe/PS1dE9 transgenic mice. Alzheimer's Research & Therapy. 4: 12. PMID 22537779 DOI: 10.1186/Alzrt110  0.622
2011 Yue WH, Wang HF, Sun LD, Tang FL, Liu ZH, Zhang HX, Li WQ, Zhang YL, Zhang Y, Ma CC, Du B, Wang LF, Ren YQ, Yang YF, Hu XF, ... ... Xu GM, et al. Genome-wide association study identifies a susceptibility locus for schizophrenia in Han Chinese at 11p11.2. Nature Genetics. 43: 1228-31. PMID 22037552 DOI: 10.1038/ng.979  0.5
2011 Tebbenkamp AT, Green C, Xu G, Denovan-Wright EM, Rising AC, Fromholt SE, Brown HH, Swing D, Mandel RJ, Tessarollo L, Borchelt DR. Transgenic mice expressing caspase-6-derived N-terminal fragments of mutant huntingtin develop neurologic abnormalities with predominant cytoplasmic inclusion pathology composed largely of a smaller proteolytic derivative. Human Molecular Genetics. 20: 2770-82. PMID 21515588 DOI: 10.1093/Hmg/Ddr176  0.779
2011 Xu G, Stevens S, Kobeissy F, Gold M, Borchelt D. P3-144: Alzheimer's amyloidosis induces global changes in protein homeostasis in the brains of transgenic mice Alzheimer's & Dementia. 7: S562-S562. DOI: 10.1016/J.Jalz.2011.05.1584  0.665
2010 Xiang Y, Xu G, Weigel-Van Aken KA. Lactic acid induces aberrant amyloid precursor protein processing by promoting its interaction with endoplasmic reticulum chaperone proteins. Plos One. 5: e13820. PMID 21072203 DOI: 10.1371/Journal.Pone.0013820  0.386
2009 Xu GG, Chan SP, Puhaindran ME, Chew WY. Prospective randomised study of intra-articular fractures of the distal radius: comparison between external fixation and plate fixation. Annals of the Academy of Medicine, Singapore. 38: 600-6. PMID 19652851  0.526
2009 Oh ES, Savonenko AV, King JF, Fangmark Tucker SM, Rudow GL, Xu G, Borchelt DR, Troncoso JC. Amyloid precursor protein increases cortical neuron size in transgenic mice. Neurobiology of Aging. 30: 1238-44. PMID 18304698 DOI: 10.1016/J.Neurobiolaging.2007.12.024  0.646
2008 Xu GG, Sathappan SS, Jaipaul J, Chan SP, Lai CH. A review of clinical pathway data of 1,663 total knee arthroplasties in a tertiary institution in Singapore. Annals of the Academy of Medicine, Singapore. 37: 924-8. PMID 19082198  0.524
2008 Xu G, Karch C, Li N, Lin N, Fromholt D, Gonzales V, Borchelt DR. Receptor-associated protein (RAP) plays a central role in modulating Abeta deposition in APP/PS1 transgenic mice. Plos One. 3: e3159. PMID 18776935 DOI: 10.1371/Journal.Pone.0003159  0.706
2008 Shaw BF, Lelie HL, Durazo A, Nersissian AM, Xu G, Chan PK, Gralla EB, Tiwari A, Hayward LJ, Borchelt DR, Valentine JS, Whitelegge JP. Detergent-insoluble aggregates associated with amyotrophic lateral sclerosis in transgenic mice contain primarily full-length, unmodified superoxide dismutase-1. The Journal of Biological Chemistry. 283: 8340-50. PMID 18192269 DOI: 10.1074/Jbc.M707751200  0.556
2007 Li QQ, Wang WJ, Xu GP, Cao XX, Xu JD, Chen Q, Tang F, Xu ZD. [CD147 and matrix metallo-proteinase (MMP) 2 and MMP9 expression in multidrug resistant breast cancer cells treated with P-glycoprotein substrate drugs]. Zhonghua Bing Li Xue Za Zhi Chinese Journal of Pathology. 36: 247-52. PMID 17706116  0.513
2007 Verret L, Jankowsky JL, Xu GM, Borchelt DR, Rampon C. Alzheimer's-type amyloidosis in transgenic mice impairs survival of newborn neurons derived from adult hippocampal neurogenesis. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 27: 6771-80. PMID 17581964 DOI: 10.1523/Jneurosci.5564-06.2007  0.754
2007 He SY, Qian ZY, Wen N, Tang FT, Xu GL, Zhou CH. Influence of Crocetin on experimental atherosclerosis in hyperlipidamic-diet quails. European Journal of Pharmacology. 554: 191-5. PMID 17109848 DOI: 10.1016/j.ejphar.2006.09.071  0.525
2006 Wang J, Xu G, Borchelt DR. Mapping superoxide dismutase 1 domains of non-native interaction: roles of intra- and intermolecular disulfide bonding in aggregation. Journal of Neurochemistry. 96: 1277-88. PMID 16441516 DOI: 10.1111/J.1471-4159.2005.03642.X  0.636
2005 Laird FM, Cai H, Savonenko AV, Farah MH, He K, Melnikova T, Wen H, Chiang HC, Xu G, Koliatsos VE, Borchelt DR, Price DL, Lee HK, Wong PC. BACE1, a major determinant of selective vulnerability of the brain to amyloid-beta amyloidogenesis, is essential for cognitive, emotional, and synaptic functions. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 25: 11693-709. PMID 16354928 DOI: 10.1523/Jneurosci.2766-05.2005  0.629
2005 Wang J, Xu G, Slunt HH, Gonzales V, Coonfield M, Fromholt D, Copeland NG, Jenkins NA, Borchelt DR. Coincident thresholds of mutant protein for paralytic disease and protein aggregation caused by restrictively expressed superoxide dismutase cDNA. Neurobiology of Disease. 20: 943-52. PMID 16046140 DOI: 10.1016/J.Nbd.2005.06.005  0.702
2005 Wang J, Xu G, Li H, Gonzales V, Fromholt D, Karch C, Copeland NG, Jenkins NA, Borchelt DR. Somatodendritic accumulation of misfolded SOD1-L126Z in motor neurons mediates degeneration: alphaB-crystallin modulates aggregation. Human Molecular Genetics. 14: 2335-47. PMID 16000321 DOI: 10.1093/Hmg/Ddi236  0.758
2005 He SY, Qian ZY, Tang FT, Wen N, Xu GL, Sheng L. Effect of crocin on experimental atherosclerosis in quails and its mechanisms. Life Sciences. 77: 907-21. PMID 15964309 DOI: 10.1016/j.lfs.2005.02.006  0.531
2005 Jankowsky JL, Melnikova T, Fadale DJ, Xu GM, Slunt HH, Gonzales V, Younkin LH, Younkin SG, Borchelt DR, Savonenko AV. Environmental enrichment mitigates cognitive deficits in a mouse model of Alzheimer's disease. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 25: 5217-24. PMID 15917461 DOI: 10.1523/Jneurosci.5080-04.2005  0.759
2005 Savonenko A, Xu GM, Melnikova T, Morton JL, Gonzales V, Wong MP, Price DL, Tang F, Markowska AL, Borchelt DR. Episodic-like memory deficits in the APPswe/PS1dE9 mouse model of Alzheimer's disease: relationships to beta-amyloid deposition and neurotransmitter abnormalities. Neurobiology of Disease. 18: 602-17. PMID 15755686 DOI: 10.1016/J.Nbd.2004.10.022  0.736
2005 Jankowsky JL, Melnikova T, Fadale DJ, Xu GM, Slunt HH, Gonzales V, Younkin LH, Younkin SG, Borchelt DR, Savonenko AV. [O2-03-01]: Environmental enrichment mitigates cognitive deficits in APP/PS1 transgenic mice Alzheimer's & Dementia. 1: S99-S99. DOI: 10.1016/J.Jalz.2005.06.342  0.71
2004 Jankowsky JL, Fadale DJ, Anderson J, Xu GM, Gonzales V, Jenkins NA, Copeland NG, Lee MK, Younkin LH, Wagner SL, Younkin SG, Borchelt DR. Mutant presenilins specifically elevate the levels of the 42 residue beta-amyloid peptide in vivo: evidence for augmentation of a 42-specific gamma secretase. Human Molecular Genetics. 13: 159-70. PMID 14645205 DOI: 10.1093/Hmg/Ddh019  0.75
2004 Cai H, Wen H, Laird FM, Chiang H, Xu G, Borchelt DR, Price DL, Wong PC. P1-222 Deletion of BACE1 prevents age-associated neuropathological abnormalities in mutant APP;PS1 mice Neurobiology of Aging. 25: S159. DOI: 10.1016/S0197-4580(04)80535-9  0.596
2004 Borchelt DR, Xu G, Wang J, Gonzales V. O4-02-01 Role of LRP and RAP in amyloid deposition Neurobiology of Aging. 25: S75. DOI: 10.1016/S0197-4580(04)80256-2  0.612
2004 Wong PC, Cai H, Laird FM, Savonenko AV, Melnikova T, Price DL, Borchelt DR, Xu G. S1-01-02 A role for APP and BACE1 in cognition Neurobiology of Aging. 25. DOI: 10.1016/S0197-4580(04)80005-8  0.511
2003 Jankowsky JL, Xu G, Fromholt D, Gonzales V, Borchelt DR. Environmental enrichment exacerbates amyloid plaque formation in a transgenic mouse model of Alzheimer disease. Journal of Neuropathology and Experimental Neurology. 62: 1220-7. PMID 14692698 DOI: 10.1093/Jnen/62.12.1220  0.778
2003 Sheng JG, Bora SH, Xu G, Borchelt DR, Price DL, Koliatsos VE. Lipopolysaccharide-induced-neuroinflammation increases intracellular accumulation of amyloid precursor protein and amyloid beta peptide in APPswe transgenic mice. Neurobiology of Disease. 14: 133-45. PMID 13678674 DOI: 10.1016/S0969-9961(03)00069-X  0.649
2003 Savonenko AV, Xu GM, Price DL, Borchelt DR, Markowska AL. Normal cognitive behavior in two distinct congenic lines of transgenic mice hyperexpressing mutant APP SWE. Neurobiology of Disease. 12: 194-211. PMID 12742740 DOI: 10.1016/S0969-9961(02)00012-8  0.622
2002 Xu G, Gonzales V, Borchelt DR. Abeta deposition does not cause the aggregation of endogenous tau in transgenic mice. Alzheimer Disease and Associated Disorders. 16: 196-201. PMID 12218652 DOI: 10.1097/00002093-200207000-00011  0.658
2002 Xu G, Gonzales V, Borchelt DR. Rapid detection of protein aggregates in the brains of Alzheimer patients and transgenic mouse models of amyloidosis. Alzheimer Disease and Associated Disorders. 16: 191-5. PMID 12218651 DOI: 10.1097/00002093-200207000-00010  0.613
2002 Jankowsky JL, Savonenko A, Schilling G, Wang J, Xu G, Borchelt DR. Transgenic mouse models of neurodegenerative disease: opportunities for therapeutic development. Current Neurology and Neuroscience Reports. 2: 457-64. PMID 12169227 DOI: 10.1007/S11910-002-0073-7  0.748
2002 Wang J, Xu G, Gonzales V, Coonfield M, Fromholt D, Copeland NG, Jenkins NA, Borchelt DR. Fibrillar inclusions and motor neuron degeneration in transgenic mice expressing superoxide dismutase 1 with a disrupted copper-binding site. Neurobiology of Disease. 10: 128-38. PMID 12127151 DOI: 10.1006/Nbdi.2002.0498  0.674
2002 Wang J, Xu G, Borchelt DR. High molecular weight complexes of mutant superoxide dismutase 1: age-dependent and tissue-specific accumulation. Neurobiology of Disease. 9: 139-48. PMID 11895367 DOI: 10.1006/Nbdi.2001.0471  0.661
2001 Lesuisse C, Xu G, Anderson J, Wong M, Jankowsky J, Holtz G, Gonzalez V, Wong PC, Price DL, Tang F, Wagner S, Borchelt DR. Hyper-expression of human apolipoprotein E4 in astroglia and neurons does not enhance amyloid deposition in transgenic mice. Human Molecular Genetics. 10: 2525-37. PMID 11709540 DOI: 10.1093/Hmg/10.22.2525  0.795
1997 Tang F, Li H, Nag S, Xu G, Chan T. Transgenic mouse and chemical lesion approaches to the study of Alzheimer's disease. Chinese Medical Journal. 110: 642-7. PMID 9594272  0.592
Low-probability matches (unlikely to be authored by this person)
2007 Xu G, Liu D, Fan Y, Yang X, Korner H, Fu YX, Uzonna JE. Lymphotoxin alpha beta 2 (membrane lymphotoxin) is critically important for resistance to Leishmania major infection in mice. Journal of Immunology (Baltimore, Md. : 1950). 179: 5358-66. PMID 17911622 DOI: 10.4049/Jimmunol.179.8.5358  0.221
2019 Yang Y, Zhong Y, Meng L, Xie P, Xu G, Peng K. [LIGHT/ TNFSF14 alleviates cisplatin-induced acute kidney injury in mice and its mechanism]. Xi Bao Yu Fen Zi Mian Yi Xue Za Zhi = Chinese Journal of Cellular and Molecular Immunology. 35: 897-902. PMID 31814566  0.212
2011 Sun S, Guo Y, Zhao G, Zhou X, Li J, Hu J, Yu H, Chen Y, Song H, Qiao F, Xu G, Yang F, Wu Y, Tomlinson S, Duan Z, et al. Complement and the alternative pathway play an important role in LPS/D-GalN-induced fulminant hepatic failure. Plos One. 6: e26838. PMID 22069473 DOI: 10.1371/Journal.Pone.0026838  0.204
2015 Chen L, Sun Y, Xu S, Fu X, Zhou Z, Lu C, Yang F, Xu G, Wu Y. [Role of LIGHT signal pathway in Chlamydia muridarum urogenital infection in mice]. Wei Sheng Wu Xue Bao = Acta Microbiologica Sinica. 55: 492-500. PMID 26211324  0.193
2016 Cai H, Chen S, Xu S, Sun Y, Bai Q, Lu C, Chen Y, Fu X, Xu G, Chen L. Deficiency of LIGHT signaling pathway exacerbates Chlamydia psittaci respiratory tract infection in mice. Microbial Pathogenesis. PMID 27725282 DOI: 10.1016/j.micpath.2016.10.006  0.177
2007 Xu G, Liu D, Okwor I, Wang Y, Korner H, Kung SK, Fu YX, Uzonna JE. LIGHT Is critical for IL-12 production by dendritic cells, optimal CD4+ Th1 cell response, and resistance to Leishmania major. Journal of Immunology (Baltimore, Md. : 1950). 179: 6901-9. PMID 17982081 DOI: 10.4049/Jimmunol.179.10.6901  0.164
2020 Zheng QY, Liang SJ, Xu F, Yang Y, Feng JL, Shen F, Zhong Y, Wu S, Shu Y, Sun DD, Xu GL. Complement component 3 prevents imiquimod-induced psoriatic skin inflammation by inhibiting apoptosis in mice. International Immunopharmacology. 85: 106692. PMID 32535539 DOI: 10.1016/j.intimp.2020.106692  0.147
2020 Wu S, Li M, Xu F, Li GQ, Han B, He XD, Li SJ, He QH, Lai XY, Zhou S, Zheng QY, Guo B, Chen J, Zhang KQ, Xu GL. Fibrinogen-like protein 2 deficiency aggravates renal fibrosis by facilitating macrophage polarization. Biomedicine & Pharmacotherapy = Biomedecine & Pharmacotherapie. 130: 110468. PMID 32795921 DOI: 10.1016/j.biopha.2020.110468  0.144
2010 Liang PH, Zhang KQ, Xu GL, Li YF, Wang LF, Nie ZL, Ye J, Wu G, Ge CG, Jin FS. Construction of a DNA vaccine encoding Flk-1 extracellular domain and C3d fusion gene and investigation of its suppressing effect on tumor growth. Cancer Immunology, Immunotherapy : Cii. 59: 93-101. PMID 19543726 DOI: 10.1007/s00262-009-0727-2  0.139
2015 Okwor I, Xu G, Tang H, Liang Y, Fu YX, Uzonna JE. Deficiency of CD40 Reveals an Important Role for LIGHT in Anti-Leishmania Immunity. Journal of Immunology (Baltimore, Md. : 1950). 195: 194-202. PMID 26026056 DOI: 10.4049/jimmunol.1401892  0.134
2020 Zhong Y, Wu S, Yang Y, Li GQ, Meng L, Zheng QY, Li Y, Xu GL, Zhang KQ, Peng KF. LIGHT aggravates sepsis-associated acute kidney injury via TLR4-MyD88-NF-κB pathway. Journal of Cellular and Molecular Medicine. PMID 32881263 DOI: 10.1111/jcmm.15815  0.132
2014 Xu GL, Chen J, Yang F, Li GQ, Zheng LX, Wu YZ. C5a/C5aR pathway is essential for the pathogenesis of murine viral fulminant hepatitis by way of potentiating Fgl2/fibroleukin expression. Hepatology (Baltimore, Md.). 60: 114-24. PMID 24604562 DOI: 10.1002/hep.27114  0.132
2020 Yang Y, Meng L, Wu S, Li Y, Zhong Y, Xu F, Zhou XC, Li GQ, Xu GL, Peng KF. LIGHT deficiency aggravates cisplatin-induced acute kidney injury by upregulating mitochondrial apoptosis. International Immunopharmacology. 89: 106999. PMID 33045563 DOI: 10.1016/j.intimp.2020.106999  0.131
2017 Tang M, Cao X, Li P, Zhang K, Li Y, Zheng QY, Li GQ, Chen J, Xu GL, Zhang KQ. Increased expression of Fibrinogen-Like Protein 2 is associated with poor prognosis in patients with clear cell renal cell carcinoma. Scientific Reports. 7: 12676. PMID 28978925 DOI: 10.1038/s41598-017-13149-x  0.126
2019 Zheng QY, Liang SJ, Xu F, Li GQ, Luo N, Wu S, Li Y, Tang M, Zhong Y, Chen J, Yang D, Sun DD, Zhang KQ, Xu GL. C5a/C5aR1 Pathway Is Critical for the Pathogenesis of Psoriasis. Frontiers in Immunology. 10: 1866. PMID 31447855 DOI: 10.3389/fimmu.2019.01866  0.126
2016 Zheng QY, Cao ZH, Hu XB, Li GQ, Dong SF, Xu GL, Zhang KQ. LIGHT/IFN-γ triggers β cells apoptosis via NF-κB/Bcl2-dependent mitochondrial pathway. Journal of Cellular and Molecular Medicine. PMID 27241100 DOI: 10.1111/jcmm.12876  0.121
2019 Tang M, Cao X, Li Y, Li GQ, He QH, Li SJ, Chen J, Xu GL, Zhang KQ. High expression of herpes virus entry mediator is associated with poor prognosis in clear cell renal cell carcinoma. American Journal of Cancer Research. 9: 975-987. PMID 31218105  0.113
2015 Cao ZH, Zheng QY, Li GQ, Hu XB, Feng SL, Xu GL, Zhang KQ. STAT1-mediated down-regulation of Bcl-2 expression is involved in IFN-γ/TNF-α-induced apoptosis in NIT-1 cells. Plos One. 10: e0120921. PMID 25811609 DOI: 10.1371/journal.pone.0120921  0.109
2004 Xu GL, Guo B, Zheng P, Yang F, Zou Q, Wu YZ. [Construction of C3b(AN42) and OVA(257-264) fusion gene and functional analysis of the fusion protein]. Xi Bao Yu Fen Zi Mian Yi Xue Za Zhi = Chinese Journal of Cellular and Molecular Immunology. 20: 651-4. PMID 15555426  0.108
2008 Guo B, Ma ZW, Li H, Xu GL, Zheng P, Zhu B, Wu YZ, Zou Q. Mapping of binding epitopes of a human decay-accelerating factor monoclonal antibody capable of enhancing rituximab-mediated complement-dependent cytotoxicity. Clinical Immunology (Orlando, Fla.). 128: 155-63. PMID 18502181 DOI: 10.1016/j.clim.2008.03.507  0.1
2018 Tang M, Cao X, Zhang K, Li Y, Zheng QY, Li GQ, He QH, Li SJ, Xu GL, Zhang KQ. Celastrol alleviates renal fibrosis by upregulating cannabinoid receptor 2 expression. Cell Death & Disease. 9: 601. PMID 29789558 DOI: 10.1038/s41419-018-0666-y  0.098
2013 Liu T, Xu G, Guo B, Fu Y, Qiu Y, Ding Y, Zheng H, Fu X, Wu Y, Xu W. An essential role for C5aR signaling in the optimal induction of a malaria-specific CD4+ T cell response by a whole-killed blood-stage vaccine. Journal of Immunology (Baltimore, Md. : 1950). 191: 178-86. PMID 23709683 DOI: 10.4049/jimmunol.1201190  0.098
2017 Zhang K, Li GQ, He QH, Li Y, Tang M, Zheng QY, Xu GL, Zhang KQ. C5a/C5aR pathway accelerates renal ischemia-reperfusion injury by downregulating PGRN expression. International Immunopharmacology. 53: 17-23. PMID 29031143 DOI: 10.1016/j.intimp.2017.10.006  0.093
2020 Chen J, Sun ZH, Chen LY, Xu F, Zhao YP, Li GQ, Tang M, Li Y, Zheng QY, Wang SF, Yang XH, Wu YZ, Xu GL. C5aR deficiency attenuates the breast cancer development via the p38/p21 axis. Aging. 12. PMID 32669478 DOI: 10.18632/aging.103468  0.092
2020 Zheng QY, Xu F, Yang Y, Sun DD, Zhong Y, Wu S, Li GQ, Gao WW, Wang T, Xu GL, Liang SJ. C5a/C5aR1 mediates IMQ-induced psoriasiform skin inflammation by promoting IL-17A production from γδ-T cells. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. PMID 32557852 DOI: 10.1096/fj.202000384R  0.09
2010 Xu GL, Zhang KQ, Guo B, Zhao TT, Yang F, Jiang M, Wang QH, Shang YH, Wu YZ. Induction of protective and therapeutic antitumor immunity by a DNA vaccine with C3d as a molecular adjuvant. Vaccine. 28: 7221-7. PMID 20800113 DOI: 10.1016/j.vaccine.2010.08.057  0.089
2022 Zheng QY, Li Y, Liang SJ, Chen XM, Tang M, Rao ZS, Li GQ, Feng JL, Zhong Y, Chen J, Xu GL, Zhang KQ. LIGHT deficiency attenuates acute kidney disease development in an in vivo experimental renal ischemia and reperfusion injury model. Cell Death Discovery. 8: 399. PMID 36163116 DOI: 10.1038/s41420-022-01188-x  0.086
2017 Chen J, Li GQ, Zhang L, Tang M, Cao X, Xu GL, Wu YZ. Complement C5a/C5aR pathway potentiates the pathogenesis of gastric cancer by down-regulating p21 expression. Cancer Letters. PMID 29031586 DOI: 10.1016/j.canlet.2017.10.003  0.081
2009 Yang D, Wang H, Ni B, He Y, Li J, Tang Y, Fu X, Wang Q, Xu G, Li K, Yang Z, Wu Y. Mutual activation of CD4+ T cells and monocytes mediated by NKG2D-MIC interaction requires IFN-gamma production in systemic lupus erythematosus. Molecular Immunology. 46: 1432-42. PMID 19200602 DOI: 10.1016/j.molimm.2008.12.010  0.078
2008 Chen H, Wang X, Su X, Yang F, Lu Y, Xu G, Dai J, Ding Q, Xi X, Wang H. Identification of a novel splicing mutation in the fibrinogen Aalpha chain gene leading to hypofibrinogenaemia in a Chinese pedigree. Haemophilia : the Official Journal of the World Federation of Hemophilia. 15: 394-7. PMID 18771425 DOI: 10.1111/j.1365-2516.2008.01835.x  0.076
2014 Cao ZH, Yin WD, Zheng QY, Feng SL, Xu GL, Zhang KQ. Caspase-3 is involved in IFN-γ- and TNF-α-mediated MIN6 cells apoptosis via NF-κB/Bcl-2 pathway. Cell Biochemistry and Biophysics. 67: 1239-48. PMID 23695786 DOI: 10.1007/s12013-013-9642-4  0.07
2016 Zheng QY, Liang SJ, Li GQ, Lv YB, Li Y, Tang M, Zhang K, Xu GL, Zhang KQ. Complement component 3 deficiency prolongs MHC-II disparate skin allograft survival by increasing the CD4(+) CD25(+) regulatory T cells population. Scientific Reports. 6: 33489. PMID 27641978 DOI: 10.1038/srep33489  0.07
2004 Xu GL, Zhu XH, Guo B, Wu YZ. Involvement of CTLA-4 in T-cell anergy induced by staphylococcal enterotoxin A in vitro. Molecular Immunology. 41: 1-8. PMID 15140570 DOI: 10.1016/j.molimm.2004.03.001  0.068
2020 Li Y, Tang M, Han B, Wu S, Li SJ, He QH, Xu F, Li GQ, Zhang K, Cao X, Zheng QY, Chen J, Yang D, Xu GL, Zhang KQ. Tumor necrosis factor superfamily 14 is critical for the development of renal fibrosis. Aging. 12. PMID 33231567 DOI: 10.18632/aging.104151  0.068
2018 Li X, Li YL, Mai J, Tao L, Qu M, Liu JY, Shen RF, Xu GL, Feng YM, Xiao HD, Wu LS, Shi L, Guo SX, Liang J, Zhu Y, et al. B alleviates Al toxicity by promoting alkalization in root transition zone via polar auxin transport. Plant Physiology. PMID 29784768 DOI: 10.1104/pp.18.00188  0.067
2021 Lan XY, Sun ZW, Xu GL, Chu CY, Qin HM, Li S, Geng X, Gao P, Boltze J, Li S. Bone Marrow Mesenchymal Stem Cells Exert Protective Effects After Ischemic Stroke Through Upregulation of Glutathione. Stem Cell Reviews and Reports. PMID 34449012 DOI: 10.1007/s12015-021-10178-y  0.056
2011 Cheng YX, Li F, Lu JY, Li M, Du P, Xu GL, Feng H. Growth of G422 glioma implanted in the mouse brain was affected by the immune ability of the host. Chinese Medical Journal. 124: 1994-8. PMID 22088459  0.055
2022 Yang G, Qu M, Xu G, Li Y, Li X, Feng Y, Xiao H, He Y, Shabala S, Demidchik V, Liu J, Yu M. pH-Dependent mitigation of aluminum toxicity in pea (Pisum sativum) roots by boron. Plant Science : An International Journal of Experimental Plant Biology. 318: 111208. PMID 35351298 DOI: 10.1016/j.plantsci.2022.111208  0.054
2016 Zheng L, Xu GM, Chen J, Chen B, Lv Z, Yang YA. Optimization of urban wastewater treatment plants process with low C/N ratio Iop Conference Series: Earth and Environmental Science. 39. DOI: 10.1088/1755-1315/39/1/012017  0.037
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