| Year |
Citation |
Score |
| 2020 |
Chen L, Wei Z, Chan KW, Li Y, Suchal K, Bi S, Huang J, Xu X, Wong PC, Lu H, van Zijl PC, Li T, Xu J. D-Glucose uptake and clearance in the tauopathy Alzheimer's disease mouse brain detected by on-resonance variable delay multiple pulse MRI. Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism. 271678X20941264. PMID 32669023 DOI: 10.1177/0271678X20941264 |
0.76 |
|
| 2019 |
Donde A, Sun M, Ling JP, Braunstein KE, Pang B, Wen X, Cheng X, Chen L, Wong PC. Splicing repression is a major function of TDP-43 in motor neurons. Acta Neuropathologica. PMID 31332509 DOI: 10.1007/s00401-019-02042-8 |
0.8 |
|
| 2019 |
Donde A, Sun M, Jeong YH, Wen X, Ling J, Lin S, Braunstein K, Nie S, Wang S, Chen L, Wong PC. Upregulation of ATG7 Attenuates Motor Neuron Dysfunction Associated with Depletion of TARDBP/TDP-43. Autophagy. PMID 31242080 DOI: 10.1080/15548627.2019.1635379 |
0.6 |
|
| 2018 |
Chen L, Wei Z, Chan K, Cai S, Liu G, Lu H, Wong PC, van Zijl PCM, Li T, Xu J. Protein aggregation linked to Alzheimer's disease revealed by saturation transfer MRI. Neuroimage. PMID 30553917 DOI: 10.1016/j.neuroimage.2018.12.018 |
0.76 |
|
| 2017 |
Donde A, Wong PC, Chen LL. Challenges and Advances in Gene Therapy Approaches for Neurodegenerative Disorders. Current Gene Therapy. PMID 29034834 DOI: 10.2174/1566523217666171013124150 |
0.6 |
|
| 2017 |
Sun M, Bell W, LaClair KD, Ling JP, Han H, Kageyama Y, Pletnikova O, Troncoso JC, Wong PC, Chen LL. Cryptic exon incorporation occurs in Alzheimer's brain lacking TDP-43 inclusion but exhibiting nuclear clearance of TDP-43. Acta Neuropathologica. PMID 28332094 DOI: 10.1007/s00401-017-1701-2 |
0.8 |
|
| 2017 |
Jeong YH, Ling JP, Lin SZ, Donde AN, Braunstein KE, Majounie E, Traynor BJ, LaClair KD, Lloyd TE, Wong PC. Tdp-43 cryptic exons are highly variable between cell types. Molecular Neurodegeneration. 12: 13. PMID 28153034 DOI: 10.1186/s13024-016-0144-x |
0.8 |
|
| 2016 |
Bedont JL, LeGates TA, Buhr E, Bathini A, Ling JP, Bell B, Wu MN, Wong PC, Van Gelder RN, Mongrain V, Hattar S, Blackshaw S. An LHX1-Regulated Transcriptional Network Controls Sleep/Wake Coupling and Thermal Resistance of the Central Circadian Clockworks. Current Biology : Cb. PMID 28017605 DOI: 10.1016/j.cub.2016.11.008 |
0.8 |
|
| 2016 |
Le NT, Chang L, Kovlyagina I, Georgiou P, Safren N, Braunstein KE, Kvarta MD, Van Dyke AM, LeGates TA, Philips T, Morrison BM, Thompson SM, Puche AC, Gould TD, Rothstein JD, ... Wong PC, et al. Motor neuron disease, TDP-43 pathology, and memory deficits in mice expressing ALS-FTD-linked UBQLN2 mutations. Proceedings of the National Academy of Sciences of the United States of America. PMID 27834214 DOI: 10.1073/pnas.1608432113 |
0.6 |
|
| 2016 |
LaClair KD, Donde A, Ling JP, Jeong YH, Chhabra R, Martin LJ, Wong PC. Depletion of TDP-43 decreases fibril and plaque β-amyloid and exacerbates neurodegeneration in an Alzheimer's mouse model. Acta Neuropathologica. PMID 27785573 DOI: 10.1007/s00401-016-1637-y |
0.84 |
|
| 2016 |
Ling JP, Chhabra R, Merran JD, Schaughency PM, Wheelan SJ, Corden JL, Wong PC. PTBP1 and PTBP2 Repress Nonconserved Cryptic Exons. Cell Reports. 17: 104-13. PMID 27681424 DOI: 10.1016/j.celrep.2016.08.071 |
0.92 |
|
| 2016 |
Li T, Braunstein KE, Zhang J, Lau A, Sibener L, Deeble C, Wong PC. The neuritic plaque facilitates pathological conversion of tau in an Alzheimer's disease mouse model. Nature Communications. 7: 12082. PMID 27373369 DOI: 10.1038/ncomms12082 |
0.76 |
|
| 2015 |
Loy SL, Lek N, Yap F, Soh SE, Padmapriya N, Tan KH, Biswas A, Yeo GS, Kwek K, Gluckman PD, Godfrey KM, Saw SM, Müller-Riemenschneider F, Chong YS, Chong MF, et al. Association of Maternal Vitamin D Status with Glucose Tolerance and Caesarean Section in a Multi-Ethnic Asian Cohort: The Growing Up in Singapore Towards Healthy Outcomes Study. Plos One. 10: e0142239. PMID 26571128 DOI: 10.1371/journal.pone.0142239 |
0.4 |
|
| 2015 |
Naguib MM, Kinne J, Chen H, Chan KH, Joseph S, Wong PC, Woo PC, Wernery R, Beer M, Wernery U, Harder TC. Outbreaks of highly pathogenic avian influenza H5N1 clade 2.3.2.1c in hunting falcons and kept wild birds in Dubai implicate intercontinental virus spread. The Journal of General Virology. PMID 26350163 DOI: 10.1099/jgv.0.000274 |
0.4 |
|
| 2015 |
Freibaum BD, Lu Y, Lopez-Gonzalez R, Kim NC, Almeida S, Lee KH, Badders N, Valentine M, Miller BL, Wong PC, Petrucelli L, Kim HJ, Gao FB, Taylor JP. GGGGCC repeat expansion in C9orf72 compromises nucleocytoplasmic transport. Nature. 525: 129-33. PMID 26308899 DOI: 10.1038/nature14974 |
0.92 |
|
| 2015 |
Megill A, Tran T, Eldred K, Lee NJ, Wong PC, Hoe HS, Kirkwood A, Lee HK. Defective Age-Dependent Metaplasticity in a Mouse Model of Alzheimer's Disease. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 35: 11346-57. PMID 26269641 DOI: 10.1523/JNEUROSCI.5289-14.2015 |
0.92 |
|
| 2015 |
Ling JP, Pletnikova O, Troncoso JC, Wong PC. NEURODEGENERATION. TDP-43 repression of nonconserved cryptic exons is compromised in ALS-FTD. Science (New York, N.Y.). 349: 650-5. PMID 26250685 DOI: 10.1126/science.aab0983 |
0.8 |
|
| 2015 |
Li PH, Chau CH, Wong PC. Melioidosis mycotic aneurysm: An uncommon complication of an uncommon disease. Respiratory Medicine Case Reports. 14: 43-6. PMID 26029577 DOI: 10.1016/j.rmcr.2014.12.005 |
0.84 |
|
| 2015 |
Shyam R, Ren Y, Lee J, Braunstein KE, Mao HQ, Wong PC. Intraventricular Delivery of siRNA Nanoparticles to the Central Nervous System. Molecular Therapy. Nucleic Acids. 4: e242. PMID 25965552 DOI: 10.1038/mtna.2015.15 |
0.84 |
|
| 2015 |
Heiman-Patterson TD, Blankenhorn EP, Sher RB, Jiang J, Welsh P, Dixon MC, Jeffrey JI, Wong P, Cox GA, Alexander GM. Genetic background effects on disease onset and lifespan of the mutant dynactin p150Glued mouse model of motor neuron disease. Plos One. 10: e0117848. PMID 25763819 DOI: 10.1371/journal.pone.0117848 |
0.92 |
|
| 2015 |
Wiesner D, Sinniger J, Henriques A, Dieterlé S, Müller HP, Rasche V, Ferger B, Dirrig-Grosch S, Soylu-Kucharz R, Petersén A, Walther P, Linkus B, Kassubek J, Wong PC, Ludolph AC, et al. Low dietary protein content alleviates motor symptoms in mice with mutant dynactin/dynein-mediated neurodegeneration. Human Molecular Genetics. 24: 2228-40. PMID 25552654 DOI: 10.1093/hmg/ddu741 |
0.92 |
|
| 2015 |
Ling JP, Pletnikova O, Troncoso JC, Wong PC. TDP-43 repression of nonconserved cryptic exons is compromised in ALS-FTD Science. 349: 650-655. DOI: 10.1126/science.aab0983 |
0.92 |
|
| 2014 |
Broekman BF, Wang C, Li Y, Rifkin-Graboi A, Saw SM, Chong YS, Kwek K, Gluckman PD, Fortier MV, Meaney MJ, Qiu A. Gestational age and neonatal brain microstructure in term born infants: a birth cohort study. Plos One. 9: e115229. PMID 25535959 DOI: 10.1371/journal.pone.0115229 |
0.4 |
|
| 2014 |
Vassar R, Kuhn PH, Haass C, Kennedy ME, Rajendran L, Wong PC, Lichtenthaler SF. Function, therapeutic potential and cell biology of BACE proteases: current status and future prospects. Journal of Neurochemistry. 130: 4-28. PMID 24646365 DOI: 10.1111/jnc.12715 |
0.92 |
|
| 2014 |
Wang H, Megill A, Wong PC, Kirkwood A, Lee HK. Postsynaptic target specific synaptic dysfunctions in the CA3 area of BACE1 knockout mice. Plos One. 9: e92279. PMID 24637500 DOI: 10.1371/journal.pone.0092279 |
0.92 |
|
| 2014 |
Savonenko AV, Melnikova T, Li T, Price DL, Wong PC. Alzheimer Disease Neurobiology of Brain Disorders: Biological Basis of Neurological and Psychiatric Disorders. 321-338. DOI: 10.1016/B978-0-12-398270-4.00021-5 |
0.92 |
|
| 2013 |
Haidet-Phillips AM, Gross SK, Williams T, Tuteja A, Sherman A, Ko M, Jeong YH, Wong PC, Maragakis NJ. Altered astrocytic expression of TDP-43 does not influence motor neuron survival. Experimental Neurology. 250: 250-9. PMID 24120466 DOI: 10.1016/j.expneurol.2013.10.004 |
0.92 |
|
| 2013 |
LaClair KD, Manaye KF, Lee DL, Allard JS, Savonenko AV, Troncoso JC, Wong PC. Treatment with bexarotene, a compound that increases apolipoprotein-E, provides no cognitive benefit in mutant APP/PS1 mice. Molecular Neurodegeneration. 8: 18. PMID 23764200 DOI: 10.1186/1750-1326-8-18 |
0.92 |
|
| 2013 |
Hatzimanolis A, McGrath JA, Wang R, Li T, Wong PC, Nestadt G, Wolyniec PS, Valle D, Pulver AE, Avramopoulos D. Multiple variants aggregate in the neuregulin signaling pathway in a subset of schizophrenia patients. Translational Psychiatry. 3: e264. PMID 23715299 DOI: 10.1038/tp.2013.33 |
0.92 |
|
| 2013 |
Stockmann M, Meyer-Ohlendorf M, Achberger K, Putz S, Demestre M, Yin H, Hendrich C, Linta L, Heinrich J, Brunner C, Proepper C, Kuh GF, Baumann B, Langer T, Schwalenstöcker B, ... ... Wong PC, et al. The dynactin p150 subunit: cell biology studies of sequence changes found in ALS/MND and Parkinsonian syndromes. Journal of Neural Transmission (Vienna, Austria : 1996). 120: 785-98. PMID 23143281 DOI: 10.1007/s00702-012-0910-z |
0.92 |
|
| 2012 |
Tsao W, Jeong YH, Lin S, Ling J, Price DL, Chiang PM, Wong PC. Rodent models of TDP-43: recent advances. Brain Research. 1462: 26-39. PMID 22608070 DOI: 10.1016/j.brainres.2012.04.031 |
0.92 |
|
| 2012 |
Savonenko AV, Melnikova T, Hiatt A, Li T, Worley PF, Troncoso JC, Wong PC, Price DL. Alzheimer's therapeutics: translation of preclinical science to clinical drug development. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 37: 261-77. PMID 21937983 DOI: 10.1038/npp.2011.211 |
0.92 |
|
| 2012 |
Kwok JS, Wong PC, Luk MC, Chan MH. Use of glycosylated ferritin assay to aid the diagnosis of adult-onset Still's disease: a local laboratory experience in Hong Kong. Rheumatology International. 32: 2583-4. PMID 21785960 DOI: 10.1007/s00296-011-2006-8 |
0.32 |
|
| 2012 |
Hayashi I, Takatori S, Urano Y, Miyake Y, Takagi J, Sakata-Yanagimoto M, Iwanari H, Osawa S, Morohashi Y, Li T, Wong PC, Chiba S, Kodama T, Hamakubo T, Tomita T, et al. Neutralization of the γ-secretase activity by monoclonal antibody against extracellular domain of nicastrin. Oncogene. 31: 787-98. PMID 21725355 DOI: 10.1038/onc.2011.265 |
0.92 |
|
| 2012 |
Chiang PM, Fortna RR, Price DL, Li T, Wong PC. Specific domains in anterior pharynx-defective 1 determine its intramembrane interactions with nicastrin and presenilin. Neurobiology of Aging. 33: 277-85. PMID 20382452 DOI: 10.1016/j.neurobiolaging.2009.12.028 |
0.92 |
|
| 2012 |
Price DL, Savonenko AV, Li T, Wong PC. Alzheimer’s disease Translational Neuroscience: Applications in Psychiatry, Neurology, and Neurodevelopmental Disorders. 149-167. DOI: 10.1017/CBO9780511980053.009 |
0.92 |
|
| 2012 |
Wong PC, Savonenko A, Li T, Price DL. Neurobiology of Alzheimer's Disease Basic Neurochemistry. 815-828. DOI: 10.1016/B978-0-12-374947-5.00046-8 |
0.92 |
|
| 2012 |
Wong PC, Chiang PM, Martin LJ, Koliatsos V, Price DL. Motor Neuron Diseases Basic Neurochemistry. 801-814. DOI: 10.1016/B978-0-12-374947-5.00045-6 |
0.92 |
|
| 2011 |
Li T, Li YM, Ahn K, Price DL, Sisodia SS, Wong PC. Increased expression of PS1 is sufficient to elevate the level and activity of γ-secretase in vivo. Plos One. 6: e28179. PMID 22140537 DOI: 10.1371/journal.pone.0028179 |
0.92 |
|
| 2011 |
Wu J, Petralia RS, Kurushima H, Patel H, Jung MY, Volk L, Chowdhury S, Shepherd JD, Dehoff M, Li Y, Kuhl D, Huganir RL, Price DL, Scannevin R, Troncoso JC, ... Wong PC, et al. Arc/Arg3.1 regulates an endosomal pathway essential for activity-dependent β-amyloid generation. Cell. 147: 615-28. PMID 22036569 DOI: 10.1016/j.cell.2011.09.036 |
0.92 |
|
| 2011 |
Chiang PM, Wong PC. Differentiation of an embryonic stem cell to hemogenic endothelium by defined factors: essential role of bone morphogenetic protein 4. Development (Cambridge, England). 138: 2833-43. PMID 21613326 DOI: 10.1242/dev.061440 |
0.92 |
|
| 2011 |
Farah MH, Pan BH, Hoffman PN, Ferraris D, Tsukamoto T, Nguyen T, Wong PC, Price DL, Slusher BS, Griffin JW. Reduced BACE1 activity enhances clearance of myelin debris and regeneration of axons in the injured peripheral nervous system. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 31: 5744-54. PMID 21490216 DOI: 10.1523/JNEUROSCI.6810-10.2011 |
0.92 |
|
| 2011 |
O'Brien RJ, Wong PC. Amyloid precursor protein processing and Alzheimer's disease. Annual Review of Neuroscience. 34: 185-204. PMID 21456963 DOI: 10.1146/annurev-neuro-061010-113613 |
0.92 |
|
| 2011 |
Tomita T, Wong PC. Selectivity to amyloid-β precursor protein cleavage provides hope against Alzheimer's. Alzheimer's Research & Therapy. 3: 7. PMID 21418547 DOI: 10.1186/alzrt66 |
0.92 |
|
| 2011 |
Nakanishi M, Patil R, Ren Y, Shyam R, Wong P, Mao HQ. Enhanced stability and knockdown efficiency of poly(ethylene glycol)-b-polyphosphoramidate/siRNA micellar nanoparticles by Co-condensation with sodium triphosphate Pharmaceutical Research. 28: 1723-1732. PMID 21387148 DOI: 10.1007/s11095-011-0408-7 |
0.92 |
|
| 2010 |
Lee HY, Ng HJ, Wong PC, Pang SM. Therapy-related leukemia cutis after adjuvant chemotherapy in a breast cancer patient. Acta Dermato-Venereologica. 90: 649-50. PMID 21057758 DOI: 10.2340/00015555-0911 |
0.52 |
|
| 2010 |
Wang H, Song L, Lee A, Laird F, Wong PC, Lee HK. Mossy fiber long-term potentiation deficits in BACE1 knock-outs can be rescued by activation of alpha7 nicotinic acetylcholine receptors. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 30: 13808-13. PMID 20943921 DOI: 10.1523/JNEUROSCI.1070-10.2010 |
0.92 |
|
| 2010 |
Shan X, Chiang PM, Price DL, Wong PC. Altered distributions of Gemini of coiled bodies and mitochondria in motor neurons of TDP-43 transgenic mice. Proceedings of the National Academy of Sciences of the United States of America. 107: 16325-30. PMID 20736350 DOI: 10.1073/pnas.1003459107 |
0.92 |
|
| 2010 |
Chiang PM, Ling J, Jeong YH, Price DL, Aja SM, Wong PC. Deletion of TDP-43 down-regulates Tbc1d1, a gene linked to obesity, and alters body fat metabolism. Proceedings of the National Academy of Sciences of the United States of America. 107: 16320-4. PMID 20660762 DOI: 10.1073/pnas.1002176107 |
0.92 |
|
| 2010 |
Hu X, Zhou X, He W, Yang J, Xiong W, Wong P, Wilson CG, Yan R. BACE1 deficiency causes altered neuronal activity and neurodegeneration. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 30: 8819-29. PMID 20592204 DOI: 10.1523/JNEUROSCI.1334-10.2010 |
0.92 |
|
| 2010 |
Wong PC, Luettgen JM, Rendina AR, Kettner CA, Xin B, Knabb RM, Wexler R, Priestley ES. BMS-593214, an active site-directed factor VIIa inhibitor: enzyme kinetics, antithrombotic and antihaemostatic studies. Thrombosis and Haemostasis. 104: 261-9. PMID 20589312 DOI: 10.1160/TH10-01-0025 |
0.32 |
|
| 2010 |
Chung CH, Siu AY, Po LL, Lam CY, Wong PC. Comparing the effectiveness of video self-instruction versus traditional classroom instruction targeted at cardiopulmonary resuscitation skills for laypersons: a prospective randomised controlled trial. Hong Kong Medical Journal = Xianggang Yi Xue Za Zhi / Hong Kong Academy of Medicine. 16: 165-70. PMID 20519751 |
0.48 |
|
| 2010 |
Chow VW, Savonenko AV, Melnikova T, Kim H, Price DL, Li T, Wong PC. Modeling an anti-amyloid combination therapy for Alzheimer's disease. Science Translational Medicine. 2: 13ra1. PMID 20371462 DOI: 10.1126/scitranslmed.3000337 |
0.92 |
|
| 2010 |
Chow VW, Mattson MP, Wong PC, Gleichmann M. An overview of APP processing enzymes and products. Neuromolecular Medicine. 12: 1-12. PMID 20232515 DOI: 10.1007/s12017-009-8104-z |
0.92 |
|
| 2010 |
Schumacher WA, Bostwick JS, Stewart AB, Steinbacher TE, Xin B, Wong PC. Effect of the direct factor Xa inhibitor apixaban in rat models of thrombosis and hemostasis. Journal of Cardiovascular Pharmacology. 55: 609-16. PMID 20224421 DOI: 10.1097/FJC.0b013e3181daded3 |
0.32 |
|
| 2010 |
Seshadri S, Kamiya A, Yokota Y, Prikulis I, Kano S, Hayashi-Takagi A, Stanco A, Eom TY, Rao S, Ishizuka K, Wong P, Korth C, Anton ES, Sawa A. Disrupted-in-Schizophrenia-1 expression is regulated by beta-site amyloid precursor protein cleaving enzyme-1-neuregulin cascade. Proceedings of the National Academy of Sciences of the United States of America. 107: 5622-7. PMID 20212127 DOI: 10.1073/pnas.0909284107 |
0.92 |
|
| 2010 |
Zhang D, He K, Raghavan N, Wang L, Crain EJ, He B, Xin B, Luettgen JM, Wong PC. Metabolism, pharmacokinetics and pharmacodynamics of the factor Xa inhibitor apixaban in rabbits. Journal of Thrombosis and Thrombolysis. 29: 70-80. PMID 19851712 DOI: 10.1007/s11239-009-0401-8 |
0.32 |
|
| 2010 |
Hoffman PN, Wong PC, Griffin JW, Price DL. Axonal Transport Disorders Encyclopedia of Neuroscience. 1205-1208. DOI: 10.1016/B978-008045046-9.00553-2 |
0.92 |
|
| 2010 |
Price DL, Savonenko AV, Albert M, Troncoso JC, Wong PC. Aging of the Brain and Alzheimer's Disease Encyclopedia of Neuroscience. 187-195. DOI: 10.1016/B978-008045046-9.00539-8 |
0.92 |
|
| 2010 |
Oh E, Lyketsos C, Wong P. Mouse Models of Alzheimer's Disease Principles and Practice of Geriatric Psychiatry: Third Edition. 252-256. DOI: 10.1002/9780470669600.ch44 |
0.92 |
|
| 2010 |
Price DL, Savonenko AV, Li T, Lee MK, Wong PC. Alzheimer Disease: Protein Misfolding, Model Systems, and Experimental Therapeutics Protein Misfolding Diseases: Current and Emerging Principles and Therapies. 231-258. DOI: 10.1002/9780470572702.ch12 |
0.92 |
|
| 2009 |
Vassar R, Kovacs DM, Yan R, Wong PC. The beta-secretase enzyme BACE in health and Alzheimer's disease: regulation, cell biology, function, and therapeutic potential. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 29: 12787-94. PMID 19828790 DOI: 10.1523/JNEUROSCI.3657-09.2009 |
0.92 |
|
| 2009 |
Hayashi I, Takatori S, Urano Y, Iwanari H, Isoo N, Osawa S, Fukuda MA, Kodama T, Hamakubo T, Li T, Wong PC, Tomita T, Iwatsubo T. Single chain variable fragment against nicastrin inhibits the gamma-secretase activity. The Journal of Biological Chemistry. 284: 27838-47. PMID 19684016 DOI: 10.1074/jbc.M109.055061 |
0.92 |
|
| 2009 |
Wong PC, Crain EJ, Watson CA, Xin B. Favorable therapeutic index of the direct factor Xa inhibitors, apixaban and rivaroxaban, compared with the thrombin inhibitor dabigatran in rabbits. Journal of Thrombosis and Haemostasis : Jth. 7: 1313-20. PMID 19500242 DOI: 10.1111/j.1538-7836.2009.03503.x |
0.32 |
|
| 2009 |
Pardossi-Piquard R, Yang SP, Kanemoto S, Gu Y, Chen F, Böhm C, Sevalle J, Li T, Wong PC, Checler F, Schmitt-Ulms G, St George-Hyslop P, Fraser PE. APH1 polar transmembrane residues regulate the assembly and activity of presenilin complexes. The Journal of Biological Chemistry. 284: 16298-307. PMID 19369254 DOI: 10.1074/jbc.M109.000067 |
0.92 |
|
| 2009 |
Wong PC, Crain EJ, Watson CA, Hua J, Schumacher WA, Rehfuss R. Clopidogrel versus prasugrel in rabbits. Effects on thrombosis, haemostasis, platelet function and response variability. Thrombosis and Haemostasis. 101: 108-15. PMID 19132196 DOI: 10.1160/TH08-07-0456 |
0.32 |
|
| 2009 |
Vetrivel KS, Meckler X, Chen Y, Nguyen PD, Seidah NG, Vassar R, Wong PC, Fukata M, Kounnas MZ, Thinakaran G. Alzheimer disease Abeta production in the absence of S-palmitoylation-dependent targeting of BACE1 to lipid rafts. The Journal of Biological Chemistry. 284: 3793-803. PMID 19074428 DOI: 10.1074/jbc.M808920200 |
0.92 |
|
| 2009 |
Qiao JX, King SR, He K, Wong PC, Rendina AR, Luettgen JM, Xin B, Knabb RM, Wexler RR, Lam PY. Highly efficacious factor Xa inhibitors containing alpha-substituted phenylcycloalkyl P4 moieties. Bioorganic & Medicinal Chemistry Letters. 19: 462-8. PMID 19046881 DOI: 10.1016/j.bmcl.2008.11.049 |
0.32 |
|
| 2009 |
Cheng H, Vetrivel KS, Drisdel RC, Meckler X, Gong P, Leem JY, Li T, Carter M, Chen Y, Nguyen P, Iwatsubo T, Tomita T, Wong PC, Green WN, Kounnas MZ, et al. S-palmitoylation of gamma-secretase subunits nicastrin and APH-1. The Journal of Biological Chemistry. 284: 1373-84. PMID 19028695 DOI: 10.1074/jbc.M806380200 |
0.92 |
|
| 2008 |
Tam WO, Wong CF, Wong PC. Endobronchial nocardiosis associated with broncholithiasis. Monaldi Archives For Chest Disease = Archivio Monaldi Per Le Malattie Del Torace / Fondazione Clinica Del Lavoro, Irccs [and] Istituto Di Clinica Tisiologica E Malattie Apparato Respiratorio, Università Di Napoli, Secondo Ateneo. 69: 183-5. PMID 19350841 |
0.84 |
|
| 2008 |
Wong PC. Translational control of BACE1 may go awry in Alzheimer's disease. Neuron. 60: 941-3. PMID 19109900 DOI: 10.1016/j.neuron.2008.12.010 |
0.92 |
|
| 2008 |
Chan-Yeung M, Lai CK, Chan KS, Cheung AH, Yao TJ, Ho AS, Ko FW, Yam LY, Wong PC, Tsang KW, Lam WK, Ho JC, Chu CM, Yu WC, Chan HS, et al. The burden of lung disease in Hong Kong: a report from the Hong Kong Thoracic Society. Respirology (Carlton, Vic.). 13: S133-65. PMID 18945323 DOI: 10.1111/j.1440-1843.2008.01394.x |
0.32 |
|
| 2008 |
Leung SK, Lam FM, Yew WW, Wong PC. Predicting impairment of diffusing capacity for Chinese patients with lung fibrosis. Respirology (Carlton, Vic.). 13: 929-30. PMID 18811893 DOI: 10.1111/j.1440-1843.2008.01372.x |
0.6 |
|
| 2008 |
Wang H, Song L, Laird F, Wong PC, Lee HK. BACE1 knock-outs display deficits in activity-dependent potentiation of synaptic transmission at mossy fiber to CA3 synapses in the hippocampus. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 28: 8677-81. PMID 18753368 DOI: 10.1523/JNEUROSCI.2440-08.2008 |
0.92 |
|
| 2008 |
Chang Y, Kong Q, Shan X, Tian G, Ilieva H, Cleveland DW, Rothstein JD, Borchelt DR, Wong PC, Lin CL. Messenger RNA oxidation occurs early in disease pathogenesis and promotes motor neuron degeneration in ALS. Plos One. 3: e2849. PMID 18682740 DOI: 10.1371/journal.pone.0002849 |
0.92 |
|
| 2008 |
Wong PC, Watson CA, Crain EJ. Arterial antithrombotic and bleeding time effects of apixaban, a direct factor Xa inhibitor, in combination with antiplatelet therapy in rabbits. Journal of Thrombosis and Haemostasis : Jth. 6: 1736-41. PMID 18647224 DOI: 10.1111/j.1538-7836.2008.03092.x |
0.32 |
|
| 2008 |
Leung SK, Yew WW, Wong PC, Tse YK, Law WS, Leung CC. American Thoracic Society/European Respiratory Society 2005 standardization of DL measurement: impact on performance. Respirology (Carlton, Vic.). 13: 728-30. PMID 18513243 DOI: 10.1111/j.1440-1843.2008.01312.x |
0.6 |
|
| 2008 |
Chávez-Gutiérrez L, Tolia A, Maes E, Li T, Wong PC, de Strooper B. Glu(332) in the Nicastrin ectodomain is essential for gamma-secretase complex maturation but not for its activity. The Journal of Biological Chemistry. 283: 20096-105. PMID 18502756 DOI: 10.1074/jbc.M803040200 |
0.92 |
|
| 2008 |
Leung SK, Yew WW, Wong PC. Lung function testing prediction equations: do they fit all? Chest. 133: 1288-9. PMID 18460533 DOI: 10.1378/chest.07-2807 |
0.6 |
|
| 2008 |
Corte JR, Fang T, Pinto DJ, Han W, Hu Z, Jiang XJ, Li YL, Gauuan JF, Hadden M, Orton D, Rendina AR, Luettgen JM, Wong PC, He K, Morin PE, et al. Structure-activity relationships of anthranilamide-based factor Xa inhibitors containing piperidinone and pyridinone P4 moieties. Bioorganic & Medicinal Chemistry Letters. 18: 2845-9. PMID 18424044 DOI: 10.1016/j.bmcl.2008.03.092 |
0.32 |
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| 2008 |
Savonenko AV, Melnikova T, Laird FM, Stewart KA, Price DL, Wong PC. Alteration of BACE1-dependent NRG1/ErbB4 signaling and schizophrenia-like phenotypes in BACE1-null mice. Proceedings of the National Academy of Sciences of the United States of America. 105: 5585-90. PMID 18385378 DOI: 10.1073/pnas.0710373105 |
0.92 |
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| 2008 |
Wong PC, Crain EJ, Xin B, Wexler RR, Lam PY, Pinto DJ, Luettgen JM, Knabb RM. Apixaban, an oral, direct and highly selective factor Xa inhibitor: in vitro, antithrombotic and antihemostatic studies. Journal of Thrombosis and Haemostasis : Jth. 6: 820-9. PMID 18315548 DOI: 10.1111/j.1538-7836.2008.02939.x |
0.32 |
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| 2008 |
Laird FM, Farah MH, Ackerley S, Hoke A, Maragakis N, Rothstein JD, Griffin J, Price DL, Martin LJ, Wong PC. Motor neuron disease occurring in a mutant dynactin mouse model is characterized by defects in vesicular trafficking. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 28: 1997-2005. PMID 18305234 DOI: 10.1523/JNEUROSCI.4231-07.2008 |
0.92 |
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| 2008 |
Chandran JS, Lin X, Zapata A, Höke A, Shimoji M, Moore SO, Galloway MP, Laird FM, Wong PC, Price DL, Bailey KR, Crawley JN, Shippenberg T, Cai H. Progressive behavioral deficits in DJ-1-deficient mice are associated with normal nigrostriatal function. Neurobiology of Disease. 29: 505-14. PMID 18187333 DOI: 10.1016/j.nbd.2007.11.011 |
0.92 |
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| 2007 |
Pinto DJ, Orwat MJ, Koch S, Rossi KA, Alexander RS, Smallwood A, Wong PC, Rendina AR, Luettgen JM, Knabb RM, He K, Xin B, Wexler RR, Lam PY. Discovery of 1-(4-methoxyphenyl)-7-oxo-6-(4-(2-oxopiperidin-1-yl)phenyl)-4,5,6,7-tetrahydro-1H-pyrazolo[3,4-c]pyridine-3-carboxamide (apixaban, BMS-562247), a highly potent, selective, efficacious, and orally bioavailable inhibitor of blood coagulation factor Xa. Journal of Medicinal Chemistry. 50: 5339-56. PMID 17914785 DOI: 10.1021/jm070245n |
0.32 |
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| 2007 |
Li T, Wen H, Brayton C, Laird FM, Ma G, Peng S, Placanica L, Wu TC, Crain BJ, Price DL, Eberhart CG, Wong PC. Moderate reduction of gamma-secretase attenuates amyloid burden and limits mechanism-based liabilities. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 27: 10849-59. PMID 17913918 DOI: 10.1523/JNEUROSCI.2152-07.2007 |
0.92 |
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| 2007 |
Li T, Wen H, Brayton C, Das P, Smithson LA, Fauq A, Fan X, Crain BJ, Price DL, Golde TE, Eberhart CG, Wong PC. Epidermal growth factor receptor and notch pathways participate in the tumor suppressor function of gamma-secretase. The Journal of Biological Chemistry. 282: 32264-73. PMID 17827153 DOI: 10.1074/jbc.M703649200 |
0.92 |
|
| 2007 |
Choi SH, Leight SN, Lee VM, Li T, Wong PC, Johnson JA, Saraiva MJ, Sisodia SS. Accelerated Abeta deposition in APPswe/PS1deltaE9 mice with hemizygous deletions of TTR (transthyretin). The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 27: 7006-10. PMID 17596449 DOI: 10.1523/JNEUROSCI.1919-07.2007 |
0.92 |
|
| 2007 |
Schumacher WA, Bostwick JS, Ogletree ML, Stewart AB, Steinbacher TE, Hua J, Price LA, Wong PC, Rehfuss RP. Biomarker optimization to track the antithrombotic and hemostatic effects of clopidogrel in rats. The Journal of Pharmacology and Experimental Therapeutics. 322: 369-77. PMID 17420297 DOI: 10.1124/jpet.106.119156 |
0.32 |
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| 2007 |
Wong PC, Crain EJ, Watson CA, Wexler RR, Lam PY, Quan ML, Knabb RM. Razaxaban, a direct factor Xa inhibitor, in combination with aspirin and/or clopidogrel improves low-dose antithrombotic activity without enhancing bleeding liability in rabbits. Journal of Thrombosis and Thrombolysis. 24: 43-51. PMID 17323133 DOI: 10.1007/s11239-007-0017-9 |
0.32 |
|
| 2007 |
Tam WO, Yew WW, Yam WC, Yuen KY, Wong PC, Tse TF. Pacemaker infections due to rapidly growing mycobacteria: further experience. The International Journal of Tuberculosis and Lung Disease : the Official Journal of the International Union Against Tuberculosis and Lung Disease. 11: 118. PMID 17217143 |
0.6 |
|
| 2007 |
Qiao JX, Cheng X, Smallheer JM, Galemmo RA, Drummond S, Pinto DJ, Cheney DL, He K, Wong PC, Luettgen JM, Knabb RM, Wexler RR, Lam PY. Pyrazole-based factor Xa inhibitors containing N-arylpiperidinyl P4 residues. Bioorganic & Medicinal Chemistry Letters. 17: 1432-7. PMID 17174550 DOI: 10.1016/j.bmcl.2006.11.071 |
0.32 |
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| 2007 |
Laird FM, Farah MH, Lee HK, Savonenko AV, Price DL, Wong PC. β-secretase: Physiological role and target validation Alzheimer's Disease: Advances in Genetics, Molecular and Cellular Biology. 59-76. DOI: 10.1007/978-0-387-35135-3_4 |
0.92 |
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| 2006 |
Hu X, Hicks CW, He W, Wong P, Macklin WB, Trapp BD, Yan R. Bace1 modulates myelination in the central and peripheral nervous system. Nature Neuroscience. 9: 1520-5. PMID 17099708 DOI: 10.1038/nn1797 |
0.92 |
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| 2006 |
Lai C, Xie C, McCormack SG, Chiang HC, Michalak MK, Lin X, Chandran J, Shim H, Shimoji M, Cookson MR, Huganir RL, Rothstein JD, Price DL, Wong PC, Martin LJ, et al. Amyotrophic lateral sclerosis 2-deficiency leads to neuronal degeneration in amyotrophic lateral sclerosis through altered AMPA receptor trafficking. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 26: 11798-806. PMID 17093100 DOI: 10.1523/JNEUROSCI.2084-06.2006 |
0.92 |
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| 2006 |
Nishitomi K, Sakaguchi G, Horikoshi Y, Gray AJ, Maeda M, Hirata-Fukae C, Becker AG, Hosono M, Sakaguchi I, Minami SS, Nakajima Y, Li HF, Takeyama C, Kihara T, Ota A, ... Wong PC, et al. BACE1 inhibition reduces endogenous Abeta and alters APP processing in wild-type mice. Journal of Neurochemistry. 99: 1555-63. PMID 17083447 DOI: 10.1111/j.1471-4159.2006.04178.x |
0.92 |
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| 2006 |
Pinto DJ, Galemmo RA, Quan ML, Orwat MJ, Clark C, Li R, Wells B, Woerner F, Alexander RS, Rossi KA, Smallwood A, Wong PC, Luettgen JM, Rendina AR, Knabb RM, et al. Discovery of potent, efficacious, and orally bioavailable inhibitors of blood coagulation factor Xa with neutral P1 moieties. Bioorganic & Medicinal Chemistry Letters. 16: 5584-9. PMID 16963264 DOI: 10.1016/j.bmcl.2006.08.027 |
0.32 |
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| 2006 |
Morais VA, Brito C, Pijak DS, Crystal AS, Fortna RR, Li T, Wong PC, Doms RW, Costa J. N-glycosylation of human nicastrin is required for interaction with the lectins from the secretory pathway calnexin and ERGIC-53. Biochimica Et Biophysica Acta. 1762: 802-10. PMID 16938437 DOI: 10.1016/j.bbadis.2006.06.018 |
0.92 |
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| 2006 |
Lam B, Wong MP, Fung SL, Lam DC, Wong PC, Mok TY, Lam FM, Ip MS, Ooi CG, Lam WK. The clinical value of autofluorescence bronchoscopy for the diagnosis of lung cancer. The European Respiratory Journal. 28: 915-9. PMID 16870657 DOI: 10.1183/09031936.06.00131405 |
0.4 |
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| 2006 |
Li YL, Fevig JM, Cacciola J, Buriak J, Rossi KA, Jona J, Knabb RM, Luettgen JM, Wong PC, Bai SA, Wexler RR, Lam PY. Preparation of 1-(3-aminobenzo[d]isoxazol-5-yl)-1H-pyrazolo[4,3-d]pyrimidin-7(6H)-ones as potent, selective, and efficacious inhibitors of coagulation factor Xa. Bioorganic & Medicinal Chemistry Letters. 16: 5176-82. PMID 16870435 DOI: 10.1016/j.bmcl.2006.07.002 |
0.32 |
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| 2006 |
Pinto DJ, Orwat MJ, Quan ML, Han Q, Galemmo RA, Amparo E, Wells B, Ellis C, He MY, Alexander RS, Rossi KA, Smallwood A, Wong PC, Luettgen JM, Rendina AR, et al. 1-[3-Aminobenzisoxazol-5'-yl]-3-trifluoromethyl-6-[2'-(3-(R)-hydroxy-N-pyrrolidinyl)methyl-[1,1']-biphen-4-yl]-1,4,5,6-tetrahydropyrazolo-[3,4-c]-pyridin-7-one (BMS-740808) a highly potent, selective, efficacious, and orally bioavailable inhibitor of blood coagulation factor Xa. Bioorganic & Medicinal Chemistry Letters. 16: 4141-7. PMID 16730984 DOI: 10.1016/j.bmcl.2006.02.069 |
0.32 |
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| 2006 |
Fevig JM, Cacciola J, Buriak J, Rossi KA, Knabb RM, Luettgen JM, Wong PC, Bai SA, Wexler RR, Lam PY. Preparation of 1-(4-methoxyphenyl)-1H-pyrazolo[4,3-d]pyrimidin-7(6H)-ones as potent, selective and bioavailable inhibitors of coagulation factor Xa. Bioorganic & Medicinal Chemistry Letters. 16: 3755-60. PMID 16682200 DOI: 10.1016/j.bmcl.2006.04.044 |
0.32 |
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| 2006 |
Quan ML, Han Q, Fevig JM, Lam PY, Bai S, Knabb RM, Luettgen JM, Wong PC, Wexler RR. Aminobenzisoxazoles with biaryl P4 moieties as potent, selective, and orally bioavailable factor Xa inhibitors. Bioorganic & Medicinal Chemistry Letters. 16: 1795-8. PMID 16434195 DOI: 10.1016/j.bmcl.2006.01.010 |
0.32 |
|
| 2005 |
Wong PC. Alzheimer disease: therapeutic targets for clinical trials. Retina (Philadelphia, Pa.). 25: S80-S81. PMID 16374352 |
0.92 |
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| 2005 |
Laird FM, Cai H, Savonenko AV, Farah MH, He K, Melnikova T, Wen H, Chiang HC, Xu G, Koliatsos VE, Borchelt DR, Price DL, Lee HK, Wong PC. BACE1, a major determinant of selective vulnerability of the brain to amyloid-beta amyloidogenesis, is essential for cognitive, emotional, and synaptic functions. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 25: 11693-709. PMID 16354928 DOI: 10.1523/JNEUROSCI.2766-05.2005 |
0.92 |
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| 2005 |
Ho PL, Chau PH, Yip PS, Ooi GC, Khong PL, Ho JC, Wong PC, Ko C, Yan C, Tsang KW. A prediction rule for clinical diagnosis of severe acute respiratory syndrome. The European Respiratory Journal. 26: 474-9. PMID 16135731 DOI: 10.1183/09031936.05.1076704 |
0.32 |
|
| 2005 |
Cai H, Lin X, Xie C, Laird FM, Lai C, Wen H, Chiang HC, Shim H, Farah MH, Hoke A, Price DL, Wong PC. Loss of ALS2 function is insufficient to trigger motor neuron degeneration in knock-out mice but predisposes neurons to oxidative stress. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 25: 7567-74. PMID 16107644 DOI: 10.1523/JNEUROSCI.1645-05.2005 |
0.92 |
|
| 2005 |
Yan SW, Wong CF, Wong PC, Cheung CF. Bronchiolitis obliterans organising pneumonia (BOOP) in a lung cancer patient after lobectomy. Monaldi Archives For Chest Disease = Archivio Monaldi Per Le Malattie Del Torace / Fondazione Clinica Del Lavoro, Irccs [and] Istituto Di Clinica Tisiologica E Malattie Apparato Respiratorio, Università Di Napoli, Secondo Ateneo. 63: 55-8. PMID 16035565 |
0.84 |
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| 2005 |
Quan ML, Lam PY, Han Q, Pinto DJ, He MY, Li R, Ellis CD, Clark CG, Teleha CA, Sun JH, Alexander RS, Bai S, Luettgen JM, Knabb RM, Wong PC, et al. Discovery of 1-(3'-aminobenzisoxazol-5'-yl)-3-trifluoromethyl-N-[2-fluoro-4- [(2'-dimethylaminomethyl)imidazol-1-yl]phenyl]-1H-pyrazole-5-carboxyamide hydrochloride (razaxaban), a highly potent, selective, and orally bioavailable factor Xa inhibitor. Journal of Medicinal Chemistry. 48: 1729-44. PMID 15771420 DOI: 10.1021/jm0497949 |
0.32 |
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| 2005 |
Lazarov O, Morfini GA, Lee EB, Farah MH, Szodorai A, DeBoer SR, Koliatsos VE, Kins S, Lee VM, Wong PC, Price DL, Brady ST, Sisodia SS. Axonal transport, amyloid precursor protein, kinesin-1, and the processing apparatus: revisited. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 25: 2386-95. PMID 15745965 DOI: 10.1523/JNEUROSCI.3089-04.2005 |
0.92 |
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| 2005 |
Zhang YW, Luo WJ, Wang H, Lin P, Vetrivel KS, Liao F, Li F, Wong PC, Farquhar MG, Thinakaran G, Xu H. Nicastrin is critical for stability and trafficking but not association of other presenilin/gamma-secretase components. The Journal of Biological Chemistry. 280: 17020-6. PMID 15711015 DOI: 10.1074/jbc.M409467200 |
0.92 |
|
| 2005 |
Ma G, Li T, Price DL, Wong PC. APH-1a is the principal mammalian APH-1 isoform present in gamma-secretase complexes during embryonic development. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 25: 192-8. PMID 15634781 DOI: 10.1523/JNEUROSCI.3814-04.2005 |
0.92 |
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| 2005 |
Price DL, Borchelt DR, Lee MK, Wong PC. Selected genetically engineered models relevant to human neurodegenerative disease Neurodegenerative Diseases: Neurobiology, Pathogenesis and Therapeutics. 176-195. DOI: 10.1017/CBO9780511544873.016 |
0.92 |
|
| 2005 |
Savonenko AV, Laird FM, Troncoso JC, Wong PC, Price DL. Role of Alzheimer's disease models in designing and testing experimental therapeutics Drug Discovery Today: Disease Models. 2: 305-312. DOI: 10.1016/j.ddmod.2005.11.006 |
0.92 |
|
| 2005 |
Price DL, Borchelt DR, Wong PC. Alzheimer's Disease. Clinical Features, Neuropathological and Biochemical Abnormalities, Genetics, Models, and Experimental Therapeutics From Neuroscience to Neurology. 445-458. DOI: 10.1016/B978-012738903-5/50028-X |
0.92 |
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| 2004 |
Vetrivel KS, Cheng H, Lin W, Sakurai T, Li T, Nukina N, Wong PC, Xu H, Thinakaran G. Association of gamma-secretase with lipid rafts in post-Golgi and endosome membranes. The Journal of Biological Chemistry. 279: 44945-54. PMID 15322084 DOI: 10.1074/jbc.M407986200 |
0.92 |
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| 2004 |
Liu J, Lillo C, Jonsson PA, Vande Velde C, Ward CM, Miller TM, Subramaniam JR, Rothstein JD, Marklund S, Andersen PM, Brännström T, Gredal O, Wong PC, Williams DS, Cleveland DW. Toxicity of familial ALS-linked SOD1 mutants from selective recruitment to spinal mitochondria. Neuron. 43: 5-17. PMID 15233913 DOI: 10.1016/j.neuron.2004.06.016 |
0.92 |
|
| 2004 |
Kwok JS, Lawton JW, Yew WW, Chau CH, Lee J, Wong PC. Protease inhibitor phenotypes and serum alpha-1-antitrypsin levels in patients with COPD: a study from Hong Kong. Respirology (Carlton, Vic.). 9: 265-70. PMID 15182280 DOI: 10.1111/j.1440-1843.2004.00560.x |
0.84 |
|
| 2004 |
Carroll MC, Girouard JB, Ulloa JL, Subramaniam JR, Wong PC, Valentine JS, Culotta VC. Mechanisms for activating Cu- and Zn-containing superoxide dismutase in the absence of the CCS Cu chaperone. Proceedings of the National Academy of Sciences of the United States of America. 101: 5964-9. PMID 15069187 DOI: 10.1073/pnas.0308298101 |
0.92 |
|
| 2004 |
Yan XX, Li T, Rominger CM, Prakash SR, Wong PC, Olson RE, Zaczek R, Li YW. Binding sites of gamma-secretase inhibitors in rodent brain: distribution, postnatal development, and effect of deafferentation. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 24: 2942-52. PMID 15044533 DOI: 10.1523/JNEUROSCI.0092-04.2004 |
0.92 |
|
| 2004 |
Jones BM, Ma ES, Peiris JS, Wong PC, Ho JC, Lam B, Lai KN, Tsang KW. Prolonged disturbances of in vitro cytokine production in patients with severe acute respiratory syndrome (SARS) treated with ribavirin and steroids. Clinical and Experimental Immunology. 135: 467-73. PMID 15008980 |
0.32 |
|
| 2004 |
Li R, Lindholm K, Yang LB, Yue X, Citron M, Yan R, Beach T, Sue L, Sabbagh M, Cai H, Wong P, Price D, Shen Y. Amyloid beta peptide load is correlated with increased beta-secretase activity in sporadic Alzheimer's disease patients. Proceedings of the National Academy of Sciences of the United States of America. 101: 3632-7. PMID 14978286 DOI: 10.1073/pnas.0205689101 |
0.92 |
|
| 2004 |
Lam MF, Ooi GC, Lam B, Ho JC, Seto WH, Ho PL, Wong PC, Liang R, Lam WK, Tsang KW. An indolent case of severe acute respiratory syndrome. American Journal of Respiratory and Critical Care Medicine. 169: 125-8. PMID 14695107 DOI: 10.1164/rccm.200306-754CR |
0.32 |
|
| 2003 |
Wong WM, Ho JC, Ooi GC, Mok T, Chan J, Hung IF, Ng W, Lam YM, Tam WO, Wong BC, Wong PC, Ho PL, Lai CL, Lam WK, Lam SK, et al. Temporal patterns of hepatic dysfunction and disease severity in patients with SARS. Jama. 290: 2663-5. PMID 14645306 DOI: 10.1001/jama.290.20.2663 |
0.32 |
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| 2003 |
Pruitt JR, Pinto DJ, Galemmo RA, Alexander RS, Rossi KA, Wells BL, Drummond S, Bostrom LL, Burdick D, Bruckner R, Chen H, Smallwood A, Wong PC, Wright MR, Bai S, et al. Discovery of 1-(2-aminomethylphenyl)-3-trifluoromethyl-N- [3-fluoro-2'-(aminosulfonyl)[1,1'-biphenyl)]-4-yl]-1H-pyrazole-5-carboxyamide (DPC602), a potent, selective, and orally bioavailable factor Xa inhibitor(1). Journal of Medicinal Chemistry. 46: 5298-315. PMID 14640539 DOI: 10.1021/jm030212h |
0.32 |
|
| 2003 |
Ooi CG, Khong PL, Ho JC, Lam B, Wong WM, Yiu WC, Wong PC, Wong CF, Lai KN, Tsang KW. Severe acute respiratory syndrome: radiographic evaluation and clinical outcome measures. Radiology. 229: 500-6. PMID 14595150 DOI: 10.1148/radiol.2292030737 |
0.84 |
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| 2003 |
Yew WW, Chan CK, Leung CC, Chau CH, Tam CM, Wong PC, Lee J. Comparative roles of levofloxacin and ofloxacin in the treatment of multidrug-resistant tuberculosis: preliminary results of a retrospective study from Hong Kong. Chest. 124: 1476-81. PMID 14555582 |
0.84 |
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| 2003 |
Lee J, Yew WW, Wong CF, Wong PC, Chiu CS. Multidrug-resistant tuberculosis in a lung transplant recipient. The Journal of Heart and Lung Transplantation : the Official Publication of the International Society For Heart Transplantation. 22: 1168-73. PMID 14550827 |
0.84 |
|
| 2003 |
Tsang KW, Mok TY, Wong PC, Ooi GC. Severe acute respiratory syndrome (SARS) in Hong Kong. Respirology (Carlton, Vic.). 8: 259-65. PMID 14528875 |
0.32 |
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| 2003 |
Ooi CG, Khong PL, Lam B, Ho JC, Yiu WC, Wong WM, Wang T, Ho PL, Wong PC, Chan RH, Lam WK, Lai KN, Tsang KW. Severe acute respiratory syndrome: relationship between radiologic and clinical parameters. Radiology. 229: 492-9. PMID 14526098 DOI: 10.1148/radiol.2292030736 |
0.32 |
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| 2003 |
Lam PY, Clark CG, Li R, Pinto DJ, Orwat MJ, Galemmo RA, Fevig JM, Teleha CA, Alexander RS, Smallwood AM, Rossi KA, Wright MR, Bai SA, He K, Luettgen JM, ... Wong PC, et al. Structure-based design of novel guanidine/benzamidine mimics: potent and orally bioavailable factor Xa inhibitors as novel anticoagulants. Journal of Medicinal Chemistry. 46: 4405-18. PMID 14521405 DOI: 10.1021/jm020578e |
0.32 |
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| 2003 |
Ho JC, Ooi GC, Mok TY, Chan JW, Hung I, Lam B, Wong PC, Li PC, Ho PL, Lam WK, Ng CK, Ip MS, Lai KN, Chan-Yeung M, Tsang KW. High-dose pulse versus nonpulse corticosteroid regimens in severe acute respiratory syndrome. American Journal of Respiratory and Critical Care Medicine. 168: 1449-56. PMID 12947028 DOI: 10.1164/rccm.200306-766OC |
0.32 |
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| 2003 |
Li T, Ma G, Cai H, Price DL, Wong PC. Nicastrin is required for assembly of presenilin/gamma-secretase complexes to mediate Notch signaling and for processing and trafficking of beta-amyloid precursor protein in mammals. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 23: 3272-7. PMID 12716934 |
0.92 |
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| 2003 |
Tsang KW, Ho PL, Ooi GC, Yee WK, Wang T, Chan-Yeung M, Lam WK, Seto WH, Yam LY, Cheung TM, Wong PC, Lam B, Ip MS, Chan J, Yuen KY, et al. A cluster of cases of severe acute respiratory syndrome in Hong Kong. The New England Journal of Medicine. 348: 1977-85. PMID 12671062 DOI: 10.1056/NEJMoa030666 |
0.32 |
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| 2003 |
Quan ML, Ellis CD, He MY, Liauw AY, Lam PY, Rossi KA, Knabb RM, Luettgen JM, Wright MR, Wong PC, Wexler RR. Nonbenzamidine isoxazoline derivatives as factor Xa inhibitors. Bioorganic & Medicinal Chemistry Letters. 13: 1023-8. PMID 12643903 DOI: 10.1016/S0960-894X(03)00080-5 |
0.32 |
|
| 2003 |
Martin LJ, Price AC, McClendon KB, Al-Abdulla NA, Subramaniam JR, Wong PC, Liu Z. Early events of target deprivation/axotomy-induced neuronal apoptosis in vivo: oxidative stress, DNA damage, p53 phosphorylation and subcellular redistribution of death proteins. Journal of Neurochemistry. 85: 234-47. PMID 12641745 |
0.92 |
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| 2003 |
Wang X, Xu L, Wang H, Grzanna R, Zhan Y, Knabb RM, Luettgen JM, Bozarth TA, Galemmo RA, Wong PC, Bernard R, Vargas H, Chopp M, Friedman SM, Feuerstein GZ. Inhibition of factor Xa reduces ischemic brain damage after thromboembolic stroke in rats. Stroke; a Journal of Cerebral Circulation. 34: 468-74. PMID 12574562 DOI: 10.1161/01.STR.0000049765.81774.A3 |
0.32 |
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| 2003 |
Quan ML, Ellis CD, He MY, Liauw AY, Woerner FJ, Alexander RS, Knabb RM, Lam PY, Luettgen JM, Wong PC, Wright MR, Wexler RR. Nonbenzamidine tetrazole derivatives as factor Xa inhibitors. Bioorganic & Medicinal Chemistry Letters. 13: 369-73. PMID 12565931 DOI: 10.1016/S0960-894X(02)00951-4 |
0.32 |
|
| 2003 |
Yang LB, Lindholm K, Yan R, Citron M, Xia W, Yang XL, Beach T, Sue L, Wong P, Price D, Li R, Shen Y. Elevated beta-secretase expression and enzymatic activity detected in sporadic Alzheimer disease. Nature Medicine. 9: 3-4. PMID 12514700 DOI: 10.1038/nm0103-3 |
0.92 |
|
| 2002 |
Wong PC, Crain EJ, Watson CA, Zaspel AM, Wright MR, Lam PY, Pinto DJ, Wexler RR, Knabb RM. Nonpeptide factor Xa inhibitors III: effects of DPC423, an orally-active pyrazole antithrombotic agent, on arterial thrombosis in rabbits. The Journal of Pharmacology and Experimental Therapeutics. 303: 993-1000. PMID 12438519 DOI: 10.1124/jpet.102.040089 |
0.32 |
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| 2002 |
Lee J, Yew WW, Chiu CS, Wong PC, Wong CF, Wang EP. Delayed sternotomy wound infection due to Paecilomyces variotii in a lung transplant recipient. The Journal of Heart and Lung Transplantation : the Official Publication of the International Society For Heart Transplantation. 21: 1131-4. PMID 12398880 |
0.84 |
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| 2002 |
Wong PC, Cai H, Borchelt DR, Price DL. Genetically engineered mouse models of neurodegenerative diseases. Nature Neuroscience. 5: 633-9. PMID 12085093 DOI: 10.1038/nn0702-633 |
0.92 |
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| 2002 |
Subramaniam JR, Lyons WE, Liu J, Bartnikas TB, Rothstein J, Price DL, Cleveland DW, Gitlin JD, Wong PC. Mutant SOD1 causes motor neuron disease independent of copper chaperone-mediated copper loading. Nature Neuroscience. 5: 301-7. PMID 11889469 DOI: 10.1038/nn823 |
0.92 |
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| 2001 |
Wong PC. Angiotensin II receptor assays. Current Protocols in Pharmacology / Editorial Board, S.J. Enna (Editor-in-Chief) ... [Et Al.]. Unit4.9. PMID 21971807 DOI: 10.1002/0471141755.ph0409s00 |
0.32 |
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| 2001 |
Wong PC, Cai H, Borchelt DR, Price DL. Genetically engineered models relevant to neurodegenerative disorders: their value for understanding disease mechanisms and designing/testing experimental therapeutics. Journal of Molecular Neuroscience : Mn. 17: 233-57. PMID 11816796 DOI: 10.1385/JMN:17:2:233 |
0.92 |
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| 2001 |
Watanabe M, Dykes-Hoberg M, Culotta VC, Price DL, Wong PC, Rothstein JD. Histological evidence of protein aggregation in mutant SOD1 transgenic mice and in amyotrophic lateral sclerosis neural tissues. Neurobiology of Disease. 8: 933-41. PMID 11741389 DOI: 10.1006/nbdi.2001.0443 |
0.92 |
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| 2001 |
Lee J, Yew WW, Wong PC, Fu KH. Non-Hodgkin's pleural lymphoma in long-standing tuberculous pyothorax mimicking suppuration. International Journal of Infectious Diseases : Ijid : Official Publication of the International Society For Infectious Diseases. 5: 167-9. PMID 11724676 |
0.84 |
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| 2001 |
Yew WW, Chau CH, Lee J, Wong PC, Leung CK. Hoarseness due to recurrent laryngeal nerve palsy from intrathoracic mycobacteriosis. The International Journal of Tuberculosis and Lung Disease : the Official Journal of the International Union Against Tuberculosis and Lung Disease. 5: 1074-5. PMID 11716346 |
0.84 |
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| 2001 |
Lesuisse C, Xu G, Anderson J, Wong M, Jankowsky J, Holtz G, Gonzalez V, Wong PC, Price DL, Tang F, Wagner S, Borchelt DR. Hyper-expression of human apolipoprotein E4 in astroglia and neurons does not enhance amyloid deposition in transgenic mice. Human Molecular Genetics. 10: 2525-37. PMID 11709540 |
0.92 |
|
| 2001 |
Wong PC, Fung SL, Lee J, Wong CF, Chau CH, Yew WW. Chronic necrotizing pulmonary aspergillosis. A report of 9 cases with analysis of clinical picture, risk factors and treatment for outcome correlation. Monaldi Archives For Chest Disease = Archivio Monaldi Per Le Malattie Del Torace / Fondazione Clinica Del Lavoro, Irccs [and] Istituto Di Clinica Tisiologica E Malattie Apparato Respiratorio, Università Di Napoli, Secondo Ateneo. 56: 202-7. PMID 11665498 |
0.84 |
|
| 2001 |
Wong PC, Price DL, Cai H. The brain's susceptibility to amyloid plaques. Science (New York, N.Y.). 293: 1434. PMID 11526940 |
0.92 |
|
| 2001 |
Fevig JM, Pinto DJ, Han Q, Quan ML, Pruitt JR, Jacobson IC, Galemmo RA, Wang S, Orwat MJ, Bostrom LL, Knabb RM, Wong PC, Lam PYS, Wexler RR. Synthesis and SAR of benzamidine factor Xa inhibitors containing a vicinally-substituted heterocyclic core. Bioorganic & Medicinal Chemistry Letters. 11: 641-5. PMID 11266160 DOI: 10.1016/S0960-894X(01)00029-4 |
0.32 |
|
| 2001 |
Cai H, Wang Y, McCarthy D, Wen H, Borchelt DR, Price DL, Wong PC. BACE1 is the major beta-secretase for generation of Abeta peptides by neurons. Nature Neuroscience. 4: 233-4. PMID 11224536 DOI: 10.1038/85064 |
0.92 |
|
| 2001 |
Pinto DJ, Orwat MJ, Wang S, Fevig JM, Quan ML, Amparo E, Cacciola J, Rossi KA, Alexander RS, Smallwood AM, Luettgen JM, Liang L, Aungst BJ, Wright MR, Knabb RM, ... Wong PC, et al. Discovery of 1-[3-(aminomethyl)phenyl]-N-3-fluoro-2'-(methylsulfonyl)-[1,1'-biphenyl]-4-yl]-3-(trifluoromethyl)-1H-pyrazole-5-carboxamide (DPC423), a highly potent, selective, and orally bioavailable inhibitor of blood coagulation factor Xa. Journal of Medicinal Chemistry. 44: 566-78. PMID 11170646 DOI: 10.1021/jm000409z |
0.32 |
|
| 2000 |
Price DL, Wong PC, Markowska AL, Lee MK, Thinakaren G, Cleveland DW, Sisodia SS, Borchelt DR. The value of transgenic models for the study of neurodegenerative diseases. Annals of the New York Academy of Sciences. 920: 179-91. PMID 11193148 DOI: 10.1111/j.1749-6632.2000.tb06920.x |
0.92 |
|
| 2000 |
Han Q, Dominguez C, Stouten PF, Park JM, Duffy DE, Galemmo RA, Rossi KA, Alexander RS, Smallwood AM, Wong PC, Wright MM, Luettgen JM, Knabb RM, Wexler RR. Design, synthesis, and biological evaluation of potent and selective amidino bicyclic factor Xa inhibitors. Journal of Medicinal Chemistry. 43: 4398-415. PMID 11087565 DOI: 10.1021/jm000113t |
0.32 |
|
| 2000 |
Sampei K, Mandir AS, Asano Y, Wong PC, Traystman RJ, Dawson VL, Dawson TM, Hurn PD. Stroke outcome in double-mutant antioxidant transgenic mice. Stroke; a Journal of Cerebral Circulation. 31: 2685-91. PMID 11062295 |
0.92 |
|
| 2000 |
Wong PC, Crain EJ, Knabb RM, Meade RP, Quan ML, Watson CA, Wexler RR, Wright MR, Slee AM. Nonpeptide factor Xa inhibitors II. Antithrombotic evaluation in a rabbit model of electrically induced carotid artery thrombosis. The Journal of Pharmacology and Experimental Therapeutics. 295: 212-8. PMID 10991981 |
0.32 |
|
| 2000 |
Pruitt JR, Pinto DJ, Estrella MJ, Bostrom LL, Knabb RM, Wong PC, Wright MR, Wexler RR. Isoxazolines and isoxazoles as factor Xa inhibitors. Bioorganic & Medicinal Chemistry Letters. 10: 685-9. PMID 10782664 DOI: 10.1016/S0960-894X(00)00097-4 |
0.32 |
|
| 2000 |
Yew WW, Chan CK, Chau CH, Tam CM, Leung CC, Wong PC, Lee J. Outcomes of patients with multidrug-resistant pulmonary tuberculosis treated with ofloxacin/levofloxacin-containing regimens. Chest. 117: 744-51. PMID 10713001 |
0.84 |
|
| 2000 |
Galemmo RA, Wells BL, Rossi KA, Alexander RS, Dominguez C, Maduskuie TP, Stouten PF, Wright MR, Aungst BJ, Wong PC, Knabb RM, Wexler RR. The de novo design and synthesis of cyclic urea inhibitors of factor Xa: optimization of the S4 ligand. Bioorganic & Medicinal Chemistry Letters. 10: 301-4. PMID 10698459 DOI: 10.1016/S0960-894X(99)00688-5 |
0.32 |
|
| 2000 |
Wong PC, Waggoner D, Subramaniam JR, Tessarollo L, Bartnikas TB, Culotta VC, Price DL, Rothstein J, Gitlin JD. Copper chaperone for superoxide dismutase is essential to activate mammalian Cu/Zn superoxide dismutase. Proceedings of the National Academy of Sciences of the United States of America. 97: 2886-91. PMID 10694572 DOI: 10.1073/pnas.040461197 |
0.92 |
|
| 2000 |
Wong WM, Wu PC, Yuen MF, Cheng CC, Yew WW, Wong PC, Tam CM, Leung CC, Lai CL. Antituberculosis drug-related liver dysfunction in chronic hepatitis B infection. Hepatology (Baltimore, Md.). 31: 201-6. PMID 10613746 DOI: 10.1002/hep.510310129 |
0.6 |
|
| 2000 |
Wong PC, Quan ML, Crain EJ, Watson CA, Wexler RR, Knabb RM. Nonpeptide factor Xa inhibitors: I. Studies with SF303 and SK549, a new class of potent antithrombotics. The Journal of Pharmacology and Experimental Therapeutics. 292: 351-7. PMID 10604970 |
0.32 |
|
| 1999 |
Wong PC, Lee J, Lam FM, Wong CF, Chau CH, Yew WW. Fibreoptic bronchoscopy in the diagnosis of lung cancer. Monaldi Archives For Chest Disease = Archivio Monaldi Per Le Malattie Del Torace / Fondazione Clinica Del Lavoro, Irccs [and] Istituto Di Clinica Tisiologica E Malattie Apparato Respiratorio, Università Di Napoli, Secondo Ateneo. 54: 394-8. PMID 10741096 |
0.84 |
|
| 1999 |
Berechid BE, Thinakaran G, Wong PC, Sisodia SS, Nye JS. Lack of requirement for presenilin1 in Notch1 signaling. Current Biology : Cb. 9: 1493-6. PMID 10607593 DOI: 10.1016/S0960-9822(00)80121-9 |
0.92 |
|
| 1999 |
Quan ML, Ellis CD, Liauw AY, Alexander RS, Knabb RM, Lam G, Wright MR, Wong PC, Wexler RR. Design and synthesis of isoxazoline derivatives as factor Xa inhibitors. 2. Journal of Medicinal Chemistry. 42: 2760-73. PMID 10425087 DOI: 10.1021/jm980406a |
0.32 |
|
| 1999 |
Quan ML, Liauw AY, Ellis CD, Pruitt JR, Carini DJ, Bostrom LL, Huang PP, Harrison K, Knabb RM, Thoolen MJ, Wong PC, Wexler RR. Design and synthesis of isoxazoline derivatives as factor Xa inhibitors. 1. Journal of Medicinal Chemistry. 42: 2752-9. PMID 10425086 DOI: 10.1021/jm980405i |
0.32 |
|
| 1999 |
Ratovitski T, Corson LB, Strain J, Wong P, Cleveland DW, Culotta VC, Borchelt DR. Variation in the biochemical/biophysical properties of mutant superoxide dismutase 1 enzymes and the rate of disease progression in familial amyotrophic lateral sclerosis kindreds. Human Molecular Genetics. 8: 1451-60. PMID 10400992 DOI: 10.1093/hmg/8.8.1451 |
0.92 |
|
| 1999 |
Yew WW, Wong PC, Lee J, Fung SL, Wong CF, Chan CY. Report of eight cases of pulmonary actinomycosis and their treatment with imipenem-cilastatin. Monaldi Archives For Chest Disease = Archivio Monaldi Per Le Malattie Del Torace / Fondazione Clinica Del Lavoro, Irccs [and] Istituto Di Clinica Tisiologica E Malattie Apparato Respiratorio, Università Di Napoli, Secondo Ateneo. 54: 126-9. PMID 10394825 |
0.84 |
|
| 1999 |
Fevig JM, Buriak J, Stouten PF, Knabb RM, Lam GN, Wong PC, Wexler RR. Preparation of pyrrolidine and isoxazolidine benzamidines as potent inhibitors of coagulation factor Xa. Bioorganic & Medicinal Chemistry Letters. 9: 1195-200. PMID 10328312 |
0.32 |
|
| 1999 |
Dominguez C, Duffy DE, Han Q, Alexander RS, Galemmo RA, Park JM, Wong PC, Amparo EC, Knabb RM, Luettgen J, Wexler RR. Design and synthesis of potent and selective 5,6-fused heterocyclic thrombin inhibitors. Bioorganic & Medicinal Chemistry Letters. 9: 925-30. PMID 10230612 |
0.32 |
|
| 1999 |
Rothstein JD, Dykes-Hoberg M, Corson LB, Becker M, Cleveland DW, Price DL, Culotta VC, Wong PC. The copper chaperone CCS is abundant in neurons and astrocytes in human and rodent brain. Journal of Neurochemistry. 72: 422-9. PMID 9886096 DOI: 10.1046/j.1471-4159.1999.0720422.x |
0.92 |
|
| 1998 |
Wong PC, Borchelt DR, Lee MK, Pardo CA, Thinakaran G, Martin LJ, Sisodia SS, Price DL. Familial amyotrophic lateral sclerosis and Alzheimer's disease. Transgenic models. Advances in Experimental Medicine and Biology. 446: 145-59. PMID 10079842 |
0.92 |
|
| 1998 |
Wong PC, Rothstein JD, Price DL. The genetic and molecular mechanisms of motor neuron disease. Current Opinion in Neurobiology. 8: 791-9. PMID 9914243 DOI: 10.1016/S0959-4388(98)80123-2 |
0.92 |
|
| 1998 |
Fevig JM, Cacciola J, Alexander RS, Knabb RM, Lam GN, Wong PC, Wexler RR. Preparation of meta-amidino-N,N-disubstituted anilines as potent inhibitors of coagulation factor Xa. Bioorganic & Medicinal Chemistry Letters. 8: 3143-8. PMID 9873692 |
0.32 |
|
| 1998 |
Naruse S, Thinakaran G, Luo JJ, Kusiak JW, Tomita T, Iwatsubo T, Qian X, Ginty DD, Price DL, Borchelt DR, Wong PC, Sisodia SS. Effects of PS1 deficiency on membrane protein trafficking in neurons. Neuron. 21: 1213-21. PMID 9856475 DOI: 10.1016/S0896-6273(00)80637-6 |
0.92 |
|
| 1998 |
Borchelt DR, Wong PC, Sisodia SS, Price DL. Transgenic mouse models of Alzheimer's disease and amyotrophic lateral sclerosis. Brain Pathology (Zurich, Switzerland). 8: 735-57. PMID 9804381 |
0.92 |
|
| 1998 |
Wong CF, Yew WW, Wong PC, Lee J. A case of concomitant tuberculosis and sarcoidosis with mycobacterial DNA present in the sarcoid lesion. Chest. 114: 626-9. PMID 9726757 |
0.84 |
|
| 1998 |
Borchelt DR, Wong PC, Becher MW, Pardo CA, Lee MK, Xu ZS, Thinakaran G, Jenkins NA, Copeland NG, Sisodia SS, Cleveland DW, Price DL, Hoffman PN. Axonal transport of mutant superoxide dismutase 1 and focal axonal abnormalities in the proximal axons of transgenic mice. Neurobiology of Disease. 5: 27-35. PMID 9702785 DOI: 10.1006/nbdi.1998.0178 |
0.92 |
|
| 1998 |
Couillard-Després S, Zhu Q, Wong PC, Price DL, Cleveland DW, Julien JP. Protective effect of neurofilament heavy gene overexpression in motor neuron disease induced by mutant superoxide dismutase. Proceedings of the National Academy of Sciences of the United States of America. 95: 9626-30. PMID 9689131 DOI: 10.1073/pnas.95.16.9626 |
0.92 |
|
| 1998 |
Wang P, Chen H, Qin H, Sankarapandi S, Becher MW, Wong PC, Zweier JL. Overexpression of human copper, zinc-superoxide dismutase (SOD1) prevents postischemic injury. Proceedings of the National Academy of Sciences of the United States of America. 95: 4556-60. PMID 9539776 DOI: 10.1073/pnas.95.8.4556 |
0.92 |
|
| 1998 |
Davis JA, Naruse S, Chen H, Eckman C, Younkin S, Price DL, Borchelt DR, Sisodia SS, Wong PC. An Alzheimer's disease-linked PS1 variant rescues the developmental abnormalities of PS1-deficient embryos. Neuron. 20: 603-9. PMID 9539132 DOI: 10.1016/S0896-6273(00)80998-8 |
0.92 |
|
| 1998 |
Eyer J, Cleveland DW, Wong PC, Peterson AC. Pathogenesis of two axonopathies does not require axonal neurofilaments. Nature. 391: 584-7. PMID 9468135 DOI: 10.1038/35378 |
0.92 |
|
| 1997 |
Price DL, Wong PC, Borchelt DR, Pardo CA, Thinakaran G, Doan AP, Lee MK, Martin LJ, Sisodia SS. Amyotrophic lateral sclerosis and Alzheimer disease. Lessons from model systems. Revue Neurologique. 153: 484-95. PMID 9683997 |
0.92 |
|
| 1997 |
Bruijn LI, Beal MF, Becher MW, Schulz JB, Wong PC, Price DL, Cleveland DW. Elevated free nitrotyrosine levels, but not protein-bound nitrotyrosine or hydroxyl radicals, throughout amyotrophic lateral sclerosis (ALS)-like disease implicate tyrosine nitration as an aberrant in vivo property of one familial ALS-linked superoxide dismutase 1 mutant. Proceedings of the National Academy of Sciences of the United States of America. 94: 7606-11. PMID 9207139 DOI: 10.1073/pnas.94.14.7606 |
0.92 |
|
| 1997 |
Wong PC, Zheng H, Chen H, Becher MW, Sirinathsinghji DJ, Trumbauer ME, Chen HY, Price DL, Van der Ploeg LH, Sisodia SS. Presenilin 1 is required for Notch1 and DII1 expression in the paraxial mesoderm. Nature. 387: 288-92. PMID 9153393 DOI: 10.1038/387288a0 |
0.92 |
|
| 1997 |
Chau CH, Yeu WW, Wong PC, Lee J, Wong CF. Usefulness of collecting routine cytologic specimens during fiberoptic bronchoscopy for endoscopically visible and nonvisible lung carcinoma. Chest. 111: 522-3. PMID 9042011 |
0.84 |
|
| 1997 |
Wang P, Wong PC, Sankarapandi S, Qin H, Chacko VP, Zweier JL. Overexpression of wild-type human SOD1 in mice prevents myocardial reperfusion injury Faseb Journal. 11: A272. |
0.92 |
|
| 1996 |
Price DL, Becher MW, Wong PC, Borchelt DR, Lee MK, Sisodia SS. Inherited neurodegenerative diseases and transgenic models. Brain Pathology (Zurich, Switzerland). 6: 467-80. PMID 8944317 DOI: 10.1111/j.1750-3639.1996.tb00876.x |
0.92 |
|
| 1996 |
Lee MK, Borchelt DR, Wong PC, Sisodia SS, Price DL. Transgenic models of neurodegenerative diseases. Current Opinion in Neurobiology. 6: 651-60. PMID 8937830 DOI: 10.1016/S0959-4388(96)80099-7 |
0.92 |
|
| 1996 |
Price DL, Koliatsos VE, Wong PC, Pardo CA, Borchelt DR, Lee MK, Cleveland DW, Griffin JW, Hoffman PN, Cork LC, Sisodia SS. Motor neuron disease and model systems: aetiologies, mechanisms and therapies. Ciba Foundation Symposium. 196: 3-13; discussion 13-. PMID 8866125 |
0.92 |
|
| 1996 |
Cleveland DW, Bruijn LI, Wong PC, Marszalek JR, Vechio JD, Lee MK, Xu XS, Borchelt DR, Sisodia SS, Price DL. Mechanisms of selective motor neuron death in transgenic mouse models of motor neuron disease. Neurology. 47: S54-61; discussion S. PMID 8858052 DOI: 10.1212/WNL.47.4_Suppl_2.54S |
0.92 |
|
| 1996 |
Xu Z, Marszalek JR, Lee MK, Wong PC, Folmer J, Crawford TO, Hsieh ST, Griffin JW, Cleveland DW. Subunit composition of neurofilaments specifies axonal diameter. The Journal of Cell Biology. 133: 1061-9. PMID 8655579 DOI: 10.1083/jcb.133.5.1061 |
0.92 |
|
| 1995 |
Borchelt DR, Guarnieri M, Wong PC, Lee MK, Slunt HS, Xu ZS, Sisodia SS, Price DL, Cleveland DW. Superoxide dismutase 1 subunits with mutations linked to familial amyotrophic lateral sclerosis do not affect wild-type subunit function. The Journal of Biological Chemistry. 270: 3234-8. PMID 7852409 DOI: 10.1074/jbc.270.7.3234 |
0.92 |
|
| 1995 |
Wong PC, Pardo CA, Borchelt DR, Lee MK, Copeland NG, Jenkins NA, Sisodia SS, Cleveland DW, Price DL. An adverse property of a familial ALS-linked SOD1 mutation causes motor neuron disease characterized by vacuolar degeneration of mitochondria. Neuron. 14: 1105-16. PMID 7605627 DOI: 10.1016/0896-6273(95)90259-7 |
0.92 |
|
| 1995 |
Wong PC, Borchelt DR. Motor neuron disease caused by mutations in superoxide dismutase 1. Current Opinion in Neurology. 8: 294-301. PMID 7582045 DOI: 10.1097/00019052-199508000-00008 |
0.92 |
|
| 1995 |
Wong PC, Marszalek J, Crawford TO, Xu Z, Hsieh ST, Griffin JW, Cleveland DW. Increasing neurofilament subunit NF-M expression reduces axonal NF-H, inhibits radial growth, and results in neurofilamentous accumulation in motor neurons. The Journal of Cell Biology. 130: 1413-22. PMID 7559762 DOI: 10.1083/jcb.130.6.1413 |
0.92 |
|
| 1994 |
Borchelt DR, Lee MK, Slunt HS, Guarnieri M, Xu ZS, Wong PC, Brown RH, Price DL, Sisodia SS, Cleveland DW. Superoxide dismutase 1 with mutations linked to familial amyotrophic lateral sclerosis possesses significant activity. Proceedings of the National Academy of Sciences of the United States of America. 91: 8292-6. PMID 8058797 DOI: 10.1073/pnas.91.17.8292 |
0.92 |
|
| 1993 |
Lee MK, Xu Z, Wong PC, Cleveland DW. Neurofilaments are obligate heteropolymers in vivo. The Journal of Cell Biology. 122: 1337-50. PMID 8376466 DOI: 10.1083/JCB.122.6.1337 |
0.84 |
|
| 1991 |
Cleveland DW, Monteiro MJ, Wong PC, Gill SR, Gearhart JD, Hoffman PN. Involvement of neurofilaments in the radial growth of axons Journal of Cell Science. 100: 85-95. PMID 1824110 DOI: 10.1242/jcs.1991.Supplement_15.12 |
0.92 |
|
| 1990 |
Gill SR, Wong PC, Monteiro MJ, Cleveland DW. Assembly properties of dominant and recessive mutations in the small mouse neurofilament (NF-L) subunit Journal of Cell Biology. 111: 2005-2019. PMID 2121744 DOI: 10.1083/jcb.111.5.2005 |
0.92 |
|
| 1990 |
Wong PC, Cleveland DW. Characterization of dominant and recessive assembly-defective mutations in mouse neurofilament NF-M Journal of Cell Biology. 111: 1987-2003. PMID 2121743 DOI: 10.1083/JCB.111.5.1987 |
0.92 |
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