Paul Greengard, Ph.D. - Publications

Affiliations: 
Yale University School of Medicine, New Haven, CT 
 1957-1967 Geigy Research Labratories 
 1969-1983 Yale University, New Haven, CT 
 1983- Molecular and Cellular Neuroscience Rockefeller University, New York, NY, United States 
Area:
neurological and psychiatric disorders, neuro- and psychoactive drugs
Website:
http://www.nobelprize.org/nobel_prizes/medicine/laureates/2000/greengard-bio.html

240 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any innacuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2019 Oh SJ, Cheng J, Jang JH, Arace J, Jeong M, Shin CH, Park J, Jin J, Greengard P, Oh YS. Hippocampal mossy cell involvement in behavioral and neurogenic responses to chronic antidepressant treatment. Molecular Psychiatry. PMID 30837688 DOI: 10.1038/s41380-019-0384-6  0.76
2019 Sagi Y, Medrihan L, George K, Barney M, McCabe KA, Greengard P. Emergence of 5-HT5A signaling in parvalbumin neurons mediates delayed antidepressant action. Molecular Psychiatry. PMID 30804492 DOI: 10.1038/s41380-019-0379-3  0.56
2019 Jin J, Bhatti DL, Lee KW, Medrihan L, Cheng J, Wei J, Zhong P, Yan Z, Kooiker C, Song C, Ahn JH, Obermair GJ, Lee A, Gresack J, Greengard P, et al. Ahnak scaffolds p11/Anxa2 complex and L-type voltage-gated calcium channel and modulates depressive behavior. Molecular Psychiatry. PMID 30760886 DOI: 10.1038/s41380-019-0371-y  0.76
2019 Wang ZJ, Zhong P, Ma K, Seo JS, Yang F, Hu Z, Zhang F, Lin L, Wang J, Liu T, Matas E, Greengard P, Yan Z. Amelioration of autism-like social deficits by targeting histone methyltransferases EHMT1/2 in Shank3-deficient mice. Molecular Psychiatry. PMID 30659288 DOI: 10.1038/s41380-019-0351-2  0.68
2019 Cheng J, Umschweif G, Leung J, Sagi Y, Greengard P. HCN2 Channels in Cholinergic Interneurons of Nucleus Accumbens Shell Regulate Depressive Behaviors. Neuron. PMID 30638901 DOI: 10.1016/j.neuron.2018.12.018  0.76
2018 Shuto T, Kuroiwa M, Sotogaku N, Kawahara Y, Oh YS, Jang JH, Shin CH, Ohnishi YN, Hanada Y, Miyakawa T, Kim Y, Greengard P, Nishi A. Obligatory roles of dopamine D1 receptors in the dentate gyrus in antidepressant actions of a selective serotonin reuptake inhibitor, fluoxetine. Molecular Psychiatry. PMID 30531938 DOI: 10.1038/s41380-018-0316-x  0.84
2017 Riessland M, Kolisnyk B, Greengard P. Reactive Dopamine Leads to Triple Trouble in Nigral Neurons. Biochemistry. 56: 6409-6410. PMID 29188990 DOI: 10.1021/acs.biochem.7b01057  0.6
2017 Nasca C, Bigio B, Zelli D, de Angelis P, Lau T, Okamoto M, Soya H, Ni J, Brichta L, Greengard P, Neve RL, Lee FS, McEwen BS. Role of the Astroglial Glutamate Exchanger xCT in Ventral Hippocampus in Resilience to Stress. Neuron. 96: 402-413.e5. PMID 29024663 DOI: 10.1016/j.neuron.2017.09.020  0.6
2017 Pirhaji L, Milani P, Dalin S, Wassie BT, Dunn DE, Fenster RJ, Avila-Pacheco J, Greengard P, Clish CB, Heiman M, Lo DC, Fraenkel E. Identifying therapeutic targets by combining transcriptional data with ordinal clinical measurements. Nature Communications. 8: 623. PMID 28931805 DOI: 10.1038/s41467-017-00353-6  0.6
2017 Medrihan L, Sagi Y, Inde Z, Krupa O, Daniels C, Peyrache A, Greengard P. Initiation of Behavioral Response to Antidepressants by Cholecystokinin Neurons of the Dentate Gyrus. Neuron. PMID 28735749 DOI: 10.1016/j.neuron.2017.06.044  0.56
2017 Musante V, Li L, Kanyo J, Lam TT, Colangelo CM, Cheng SK, Brody H, Greengard P, Le Novère N, Nairn AC. Reciprocal regulation of ARPP-16 by PKA and MAST-3 kinases provides a cAMP-regulated switch in protein phosphatase 2A inhibition. Elife. 6. PMID 28613156 DOI: 10.7554/eLife.24998  0.88
2017 Bustos V, Pulina MV, Kelahmetoglu Y, Sinha SC, Gorelick FS, Flajolet M, Greengard P. Bidirectional regulation of Aβ levels by Presenilin 1. Proceedings of the National Academy of Sciences of the United States of America. PMID 28533411 DOI: 10.1073/pnas.1705235114  0.92
2017 Bustos V, Pulina MV, Bispo A, Lam A, Flajolet M, Gorelick FS, Greengard P. Phosphorylated Presenilin 1 decreases β-amyloid by facilitating autophagosome-lysosome fusion. Proceedings of the National Academy of Sciences of the United States of America. PMID 28533369 DOI: 10.1073/pnas.1705240114  0.92
2017 Andrade EC, Musante V, Horiuchi A, Matsuzaki H, Brody AH, Wu T, Greengard P, Taylor JR, Nairn AC. ARPP-16 is a striatal-enriched inhibitor of protein phosphatase 2A regulated by microtubule-associated serine/threonine kinase 3 (Mast 3 kinase). The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. PMID 28167675 DOI: 10.1523/JNEUROSCI.4559-15.2017  0.88
2017 Green H, Zhang X, Tiklova K, Volakakis N, Brodin L, Berg L, Greengard P, Perlmann T, Svenningsson P. Alterations of p11 in brain tissue and peripheral blood leukocytes in Parkinson's disease. Proceedings of the National Academy of Sciences of the United States of America. PMID 28137881 DOI: 10.1073/pnas.1621218114  1
2017 Netzer WJ, Bettayeb K, Sinha SC, Flajolet M, Greengard P, Bustos V. Gleevec shifts APP processing from a β-cleavage to a nonamyloidogenic cleavage. Proceedings of the National Academy of Sciences of the United States of America. PMID 28115709 DOI: 10.1073/pnas.1620963114  0.92
2017 Ceglia I, Lee KW, Cahill ME, Graves SM, Dietz D, Surmeier DJ, Nestler EJ, Nairn AC, Greengard P, Kim Y. WAVE1 in neurons expressing the D1 dopamine receptor regulates cellular and behavioral actions of cocaine. Proceedings of the National Academy of Sciences of the United States of America. PMID 28115704 DOI: 10.1073/pnas.1621185114  1
2016 Estep CM, Galtieri DJ, Zampese E, Goldberg JA, Brichta L, Greengard P, Surmeier DJ. Transient Activation of GABAB Receptors Suppresses SK Channel Currents in Substantia Nigra Pars Compacta Dopaminergic Neurons. Plos One. 11: e0169044. PMID 28036359 DOI: 10.1371/journal.pone.0169044  0.6
2016 Nishi A, Matamales M, Musante V, Valjent E, Kuroiwa M, Kitahara Y, Rebholz H, Greengard P, Girault JA, Nairn AC. Glutamate counteracts dopamine/PKA signaling via dephosphorylation of DARPP-32 Ser97 and alteration of its cytonuclear distribution. The Journal of Biological Chemistry. PMID 27998980 DOI: 10.1074/jbc.M116.752402  0.92
2016 Milosevic A, Liebmann T, Knudsen M, Schintu N, Svenningsson P, Greengard P. Cell- and region-specific expression of depression-related protein p11 (S100a10) in the brain. The Journal of Comparative Neurology. PMID 27616678 DOI: 10.1002/cne.24113  1
2016 Liebmann T, Renier N, Bettayeb K, Greengard P, Tessier-Lavigne M, Flajolet M. Three-Dimensional Study of Alzheimer's Disease Hallmarks Using the iDISCO Clearing Method. Cell Reports. PMID 27425620 DOI: 10.1016/j.celrep.2016.06.060  0.92
2016 Shen W, Plotkin JL, Francardo V, Ko WK, Xie Z, Li Q, Fieblinger T, Wess J, Neubig RR, Lindsley CW, Conn PJ, Greengard P, Bezard E, Cenci MA, Surmeier DJ. M4 Muscarinic Receptor Signaling Ameliorates Striatal Plasticity Deficits in Models of L-DOPA-Induced Dyskinesia. Neuron. 90: 1139. PMID 27253449 DOI: 10.1016/j.neuron.2016.05.017  0.6
2016 Li Z, Kelly L, Heiman M, Greengard P, Friedman JM. Hypothalamic Amylin Acts in Concert with Leptin to Regulate Food Intake. Cell Metabolism. 23: 945. PMID 27166950 DOI: 10.1016/j.cmet.2016.04.014  0.6
2016 Bettayeb K, Hooli BV, Parrado AR, Randolph L, Varotsis D, Aryal S, Gresack J, Tanzi RE, Greengard P, Flajolet M. Relevance of the COPI complex for Alzheimer's disease progression in vivo. Proceedings of the National Academy of Sciences of the United States of America. PMID 27114526 DOI: 10.1073/pnas.1604176113  1
2016 Bettayeb K, Chang JC, Luo W, Aryal S, Varotsis D, Randolph L, Netzer WJ, Greengard P, Flajolet M. δ-COP modulates Aβ peptide formation via retrograde trafficking of APP. Proceedings of the National Academy of Sciences of the United States of America. PMID 27114525 DOI: 10.1073/pnas.1604156113  1
2016 Marongiu R, Arango-Lievano M, Francardo V, Morgenstern P, Zhang X, Cenci MA, Svenningsson P, Greengard P, Kaplitt MG. Gene therapy blockade of dorsal striatal p11 improves motor function and dyskinesia in parkinsonian mice. Proceedings of the National Academy of Sciences of the United States of America. PMID 26787858 DOI: 10.1073/pnas.1524387113  1
2016 Schintu N, Zhang X, Alvarsson A, Marongiu R, Kaplitt MG, Greengard P, Svenningsson P. p11 modulates L-DOPA therapeutic effects and dyskinesia via distinct cell types in experimental Parkinsonism. Proceedings of the National Academy of Sciences of the United States of America. PMID 26787846 DOI: 10.1073/pnas.1524303113  1
2016 Virk MS, Sagi Y, Medrihan L, Leung J, Kaplitt MG, Greengard P. Opposing roles for serotonin in cholinergic neurons of the ventral and dorsal striatum. Proceedings of the National Academy of Sciences of the United States of America. PMID 26733685 DOI: 10.1073/pnas.1524183113  1
2015 Li Z, Kelly L, Heiman M, Greengard P, Friedman JM. Hypothalamic Amylin Acts in Concert with Leptin to Regulate Food Intake. Cell Metabolism. 22: 1059-67. PMID 26655697 DOI: 10.1016/j.cmet.2015.10.012  1
2015 Engmann O, Giralt A, Gervasi N, Marion-Poll L, Gasmi L, Filhol O, Picciotto MR, Gilligan D, Greengard P, Nairn AC, Hervé D, Girault JA. DARPP-32 interaction with adducin may mediate rapid environmental effects on striatal neurons. Nature Communications. 6: 10099. PMID 26639316 DOI: 10.1038/ncomms10099  1
2015 Shen W, Plotkin JL, Francardo V, Ko WK, Xie Z, Li Q, Fieblinger T, Wess J, Neubig RR, Lindsley CW, Conn PJ, Greengard P, Bezard E, Cenci MA, Surmeier DJ. M4 Muscarinic Receptor Signaling Ameliorates Striatal Plasticity Deficits in Models of L-DOPA-Induced Dyskinesia. Neuron. 88: 762-773. PMID 26590347 DOI: 10.1016/j.neuron.2015.10.039  1
2015 Ceglia I, Reitz C, Gresack J, Ahn JH, Bustos V, Bleck M, Zhang X, Martin G, Simon SM, Nairn AC, Greengard P, Kim Y. APP intracellular domain-WAVE1 pathway reduces amyloid-β production. Nature Medicine. PMID 26280122 DOI: 10.1038/nm.3924  1
2015 Brichta L, Shin W, Jackson-Lewis V, Blesa J, Yap EL, Walker Z, Zhang J, Roussarie JP, Alvarez MJ, Califano A, Przedborski S, Greengard P. Identification of neurodegenerative factors using translatome-regulatory network analysis. Nature Neuroscience. PMID 26214373 DOI: 10.1038/nn.4070  1
2015 Wang H, Warner-Schmidt J, Varela S, Enikolopov G, Greengard P, Flajolet M. Norbin ablation results in defective adult hippocampal neurogenesis and depressive-like behavior in mice. Proceedings of the National Academy of Sciences of the United States of America. 112: 9745-50. PMID 26195764 DOI: 10.1073/pnas.1510291112  0.92
2015 Plattner F, Hayashi K, Hernández A, Benavides DR, Tassin TC, Tan C, Day J, Fina MW, Yuen EY, Yan Z, Goldberg MS, Nairn AC, Greengard P, Nestler EJ, Taussig R, et al. The role of ventral striatal cAMP signaling in stress-induced behaviors. Nature Neuroscience. 18: 1094-100. PMID 26192746 DOI: 10.1038/nn.4066  1
2015 Lazenka MF, Tomarchio A, Lichtman AH, Greengard P, Flajolet M, Selley DE, Sim-Selley LJ. Role of dopamine type 1 receptors and DARPP-32 in Δ9-THC-mediated induction of ΔFosB in the mouse forebrain. The Journal of Pharmacology and Experimental Therapeutics. PMID 26099530 DOI: 10.1124/jpet.115.224428  1
2015 Uematsu K, Heiman M, Zelenina M, Padovan J, Chait BT, Aperia A, Nishi A, Greengard P. Protein kinase A directly phosphorylates metabotropic glutamate receptor 5 to modulate its function. Journal of Neurochemistry. 132: 677-86. PMID 25639954 DOI: 10.1111/jnc.13038  1
2014 Brichta L, Greengard P. Molecular determinants of selective dopaminergic vulnerability in Parkinson's disease: an update. Frontiers in Neuroanatomy. 8: 152. PMID 25565977 DOI: 10.3389/fnana.2014.00152  1
2014 Sagi Y, Heiman M, Peterson JD, Musatov S, Scarduzio M, Logan SM, Kaplitt MG, Surmeier DJ, Heintz N, Greengard P. Nitric oxide regulates synaptic transmission between spiny projection neurons. Proceedings of the National Academy of Sciences of the United States of America. 111: 17636-41. PMID 25413364 DOI: 10.1073/pnas.1420162111  1
2014 Fieblinger T, Graves SM, Sebel LE, Alcacer C, Plotkin JL, Gertler TS, Chan CS, Heiman M, Greengard P, Cenci MA, Surmeier DJ. Cell type-specific plasticity of striatal projection neurons in parkinsonism and L-DOPA-induced dyskinesia. Nature Communications. 5: 5316. PMID 25360704 DOI: 10.1038/ncomms6316  1
2014 Xu J, Chatterjee M, Baguley TD, Brouillette J, Kurup P, Ghosh D, Kanyo J, Zhang Y, Seyb K, Ononenyi C, Foscue E, Anderson GM, Gresack J, Cuny GD, Glicksman MA, ... Greengard P, et al. Inhibitor of the tyrosine phosphatase STEP reverses cognitive deficits in a mouse model of Alzheimer's disease. Plos Biology. 12: e1001923. PMID 25093460 DOI: 10.1371/journal.pbio.1001923  1
2014 Plotkin JL, Day M, Peterson JD, Xie Z, Kress GJ, Rafalovich I, Kondapalli J, Gertler TS, Flajolet M, Greengard P, Stavarache M, Kaplitt MG, Rosinski J, Chan CS, Surmeier DJ. Impaired TrkB receptor signaling underlies corticostriatal dysfunction in Huntington's disease. Neuron. 83: 178-88. PMID 24991961 DOI: 10.1016/j.neuron.2014.05.032  1
2014 Meyer DA, Torres-Altoro MI, Tan Z, Tozzi A, Di Filippo M, DiNapoli V, Plattner F, Kansy JW, Benkovic SA, Huber JD, Miller DB, Greengard P, Calabresi P, Rosen CL, Bibb JA. Ischemic stroke injury is mediated by aberrant Cdk5. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 34: 8259-67. PMID 24920629 DOI: 10.1523/JNEUROSCI.4368-13.2014  1
2014 Heiman M, Kulicke R, Fenster RJ, Greengard P, Heintz N. Cell type-specific mRNA purification by translating ribosome affinity purification (TRAP). Nature Protocols. 9: 1282-91. PMID 24810037 DOI: 10.1038/nprot.2014.085  1
2014 Arango-Lievano M, Schwarz JT, Vernov M, Wilkinson MB, Bradbury K, Feliz A, Marongiu R, Gelfand Y, Warner-Schmidt J, Nestler EJ, Greengard P, Russo SJ, Kaplitt MG. Cell-type specific expression of p11 controls cocaine reward. Biological Psychiatry. 76: 794-801. PMID 24725970 DOI: 10.1016/j.biopsych.2014.02.012  1
2014 Heiman M, Heilbut A, Francardo V, Kulicke R, Fenster RJ, Kolaczyk ED, Mesirov JP, Surmeier DJ, Cenci MA, Greengard P. Molecular adaptations of striatal spiny projection neurons during levodopa-induced dyskinesia. Proceedings of the National Academy of Sciences of the United States of America. 111: 4578-83. PMID 24599591 DOI: 10.1073/pnas.1401819111  1
2014 Tian Y, Chang JC, Greengard P, Flajolet M. The convergence of endosomal and autophagosomal pathways: implications for APP-CTF degradation. Autophagy. 10: 694-6. PMID 24447917 DOI: 10.4161/auto.27802  1
2013 Tan CL, Plotkin JL, Venø MT, von Schimmelmann M, Feinberg P, Mann S, Handler A, Kjems J, Surmeier DJ, O'Carroll D, Greengard P, Schaefer A. MicroRNA-128 governs neuronal excitability and motor behavior in mice. Science (New York, N.Y.). 342: 1254-8. PMID 24311694 DOI: 10.1126/science.1244193  1
2013 Borroto-Escuela DO, Flajolet M, Agnati LF, Greengard P, Fuxe K. Bioluminescence resonance energy transfer methods to study G protein-coupled receptor-receptor tyrosine kinase heteroreceptor complexes. Methods in Cell Biology. 117: 141-64. PMID 24143976 DOI: 10.1016/B978-0-12-408143-7.00008-6  1
2013 Tian Y, Chang JC, Fan EY, Flajolet M, Greengard P. Adaptor complex AP2/PICALM, through interaction with LC3, targets Alzheimer's APP-CTF for terminal degradation via autophagy. Proceedings of the National Academy of Sciences of the United States of America. 110: 17071-6. PMID 24067654 DOI: 10.1073/pnas.1315110110  1
2013 Svenningsson P, Kim Y, Warner-Schmidt J, Oh YS, Greengard P. p11 and its role in depression and therapeutic responses to antidepressants. Nature Reviews. Neuroscience. 14: 673-80. PMID 24002251 DOI: 10.1038/nrn3564  1
2013 Brichta L, Greengard P, Flajolet M. Advances in the pharmacological treatment of Parkinson's disease: targeting neurotransmitter systems. Trends in Neurosciences. 36: 543-54. PMID 23876424 DOI: 10.1016/j.tins.2013.06.003  1
2013 Altindis E, Alpar MA, Aksay E, Beckwith J, Bökel C, Curl RF, Darnell RB, Elledge SJ, Erman B, Frahm J, Goff SP, Greengard P, Hoffmann R, Ilhan B, Kaslin J, et al. Turkey must end violent response to protests. Science (New York, N.Y.). 341: 236. PMID 23869001 DOI: 10.1126/science.341.6143.236-a  1
2013 Jordi E, Heiman M, Marion-Poll L, Guermonprez P, Cheng SK, Nairn AC, Greengard P, Girault JA. Differential effects of cocaine on histone posttranslational modifications in identified populations of striatal neurons. Proceedings of the National Academy of Sciences of the United States of America. 110: 9511-6. PMID 23690581 DOI: 10.1073/pnas.1307116110  1
2013 Oh YS, Gao P, Lee KW, Ceglia I, Seo JS, Zhang X, Ahn JH, Chait BT, Patel DJ, Kim Y, Greengard P. SMARCA3, a chromatin-remodeling factor, is required for p11-dependent antidepressant action. Cell. 152: 831-43. PMID 23415230 DOI: 10.1016/j.cell.2013.01.014  1
2013 Greengard P. A conversation with Paul Greengard. Interview by Eric J Nestler. Annual Review of Pharmacology and Toxicology. 53: 1-16. PMID 23294305 DOI: 10.1146/annurev-pharmtox-062712-160347  1
2013 Rebholz H, Zhou M, Nairn AC, Greengard P, Flajolet M. Selective knockout of the casein kinase 2 in d1 medium spiny neurons controls dopaminergic function. Biological Psychiatry. 74: 113-21. PMID 23290496 DOI: 10.1016/j.biopsych.2012.11.013  1
2012 Liebmann T, Kruusmägi M, Sourial-Bassillious N, Bondar A, Svenningsson P, Flajolet M, Greengard P, Scott L, Brismar H, Aperia A. A noncanonical postsynaptic transport route for a GPCR belonging to the serotonin receptor family. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 32: 17998-8008. PMID 23238716 DOI: 10.1523/JNEUROSCI.1804-12.2012  1
2012 Bettayeb K, Oumata N, Zhang Y, Luo W, Bustos V, Galons H, Greengard P, Meijer L, Flajolet M. Small-molecule inducers of Aβ-42 peptide production share a common mechanism of action. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 26: 5115-23. PMID 22972917 DOI: 10.1096/fj.12-212985  1
2012 Lerner AG, Upton JP, Praveen PV, Ghosh R, Nakagawa Y, Igbaria A, Shen S, Nguyen V, Backes BJ, Heiman M, Heintz N, Greengard P, Hui S, Tang Q, Trusina A, et al. IRE1α induces thioredoxin-interacting protein to activate the NLRP3 inflammasome and promote programmed cell death under irremediable ER stress. Cell Metabolism. 16: 250-64. PMID 22883233 DOI: 10.1016/j.cmet.2012.07.007  1
2012 Chan CS, Peterson JD, Gertler TS, Glajch KE, Quintana RE, Cui Q, Sebel LE, Plotkin JL, Shen W, Heiman M, Heintz N, Greengard P, Surmeier DJ. Strain-specific regulation of striatal phenotype in Drd2-eGFP BAC transgenic mice. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 32: 9124-32. PMID 22764222 DOI: 10.1523/JNEUROSCI.0229-12.2012  1
2012 Santini E, Feyder M, Gangarossa G, Bateup HS, Greengard P, Fisone G. Dopamine- and cAMP-regulated phosphoprotein of 32-kDa (DARPP-32)-dependent activation of extracellular signal-regulated kinase (ERK) and mammalian target of rapamycin complex 1 (mTORC1) signaling in experimental parkinsonism. The Journal of Biological Chemistry. 287: 27806-12. PMID 22753408 DOI: 10.1074/jbc.M112.388413  1
2012 Warner-Schmidt JL, Schmidt EF, Marshall JJ, Rubin AJ, Arango-Lievano M, Kaplitt MG, Ibañez-Tallon I, Heintz N, Greengard P. Cholinergic interneurons in the nucleus accumbens regulate depression-like behavior. Proceedings of the National Academy of Sciences of the United States of America. 109: 11360-5. PMID 22733786 DOI: 10.1073/pnas.1209293109  1
2012 Schmidt EF, Warner-Schmidt JL, Otopalik BG, Pickett SB, Greengard P, Heintz N. Identification of the cortical neurons that mediate antidepressant responses. Cell. 149: 1152-63. PMID 22632977 DOI: 10.1016/j.cell.2012.03.038  1
2012 Chen Y, Liu Y, Cottingham C, McMahon L, Jiao K, Greengard P, Wang Q. Neurabin scaffolding of adenosine receptor and RGS4 regulates anti-seizure effect of endogenous adenosine. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 32: 2683-95. PMID 22357852 DOI: 10.1523/JNEUROSCI.4125-11.2011  1
2012 Davis MM, Olausson P, Greengard P, Taylor JR, Nairn AC. Regulator of calmodulin signaling knockout mice display anxiety-like behavior and motivational deficits. The European Journal of Neuroscience. 35: 300-8. PMID 22250817 DOI: 10.1111/j.1460-9568.2011.07956.x  1
2012 Kuroiwa M, Snyder GL, Shuto T, Fukuda A, Yanagawa Y, Benavides DR, Nairn AC, Bibb JA, Greengard P, Nishi A. Phosphodiesterase 4 inhibition enhances the dopamine D1 receptor/PKA/DARPP-32 signaling cascade in frontal cortex. Psychopharmacology. 219: 1065-79. PMID 21833500 DOI: 10.1007/s00213-011-2436-8  1
2011 Ahn JH, Kim Y, Kim HS, Greengard P, Nairn AC. Protein kinase C-dependent dephosphorylation of tyrosine hydroxylase requires the B56δ heterotrimeric form of protein phosphatase 2A. Plos One. 6: e26292. PMID 22046270 DOI: 10.1371/journal.pone.0026292  1
2011 Walaas SI, Hemmings HC, Greengard P, Nairn AC. Beyond the dopamine receptor: regulation and roles of serine/threonine protein phosphatases. Frontiers in Neuroanatomy. 5: 50. PMID 21904525 DOI: 10.3389/fnana.2011.00050  1
2011 Zhang Y, Kurup P, Xu J, Anderson GM, Greengard P, Nairn AC, Lombroso PJ. Reduced levels of the tyrosine phosphatase STEP block β amyloid-mediated GluA1/GluA2 receptor internalization. Journal of Neurochemistry. 119: 664-72. PMID 21883219 DOI: 10.1111/j.1471-4159.2011.07450.x  1
2011 Warner-Schmidt JL, Vanover KE, Chen EY, Marshall JJ, Greengard P. Antidepressant effects of selective serotonin reuptake inhibitors (SSRIs) are attenuated by antiinflammatory drugs in mice and humans. Proceedings of the National Academy of Sciences of the United States of America. 108: 9262-7. PMID 21518864 DOI: 10.1073/pnas.1104836108  1
2011 Tian Y, Bustos V, Flajolet M, Greengard P. A small-molecule enhancer of autophagy decreases levels of Abeta and APP-CTF via Atg5-dependent autophagy pathway. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 25: 1934-42. PMID 21368103 DOI: 10.1096/fj.10-175158  1
2011 Egeland M, Warner-Schmidt J, Greengard P, Svenningsson P. Co-expression of serotonin 5-HT(1B) and 5-HT(4) receptors in p11 containing cells in cerebral cortex, hippocampus, caudate-putamen and cerebellum. Neuropharmacology. 61: 442-50. PMID 21300076 DOI: 10.1016/j.neuropharm.2011.01.046  1
2011 Christoffel DJ, Golden SA, Dumitriu D, Robison AJ, Janssen WG, Ahn HF, Krishnan V, Reyes CM, Han MH, Ables JL, Eisch AJ, Dietz DM, Ferguson D, Neve RL, Greengard P, et al. IκB kinase regulates social defeat stress-induced synaptic and behavioral plasticity. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 31: 314-21. PMID 21209217 DOI: 10.1523/JNEUROSCI.4763-10.2011  1
2011 Schaefer A, Tarakhovsky A, Greengard P. Epigenetic mechanisms of mental retardation. Progress in Drug Research. Fortschritte Der Arzneimittelforschung. ProgrèS Des Recherches Pharmaceutiques. 67: 125-46. PMID 21141728 DOI: 10.1007/978-3-7643-8989-5_7  1
2010 Wang H, Nong Y, Bazan F, Greengard P, Flajolet M. Norbin: A promising central nervous system regulator. Communicative & Integrative Biology. 3: 487-90. PMID 21331221 DOI: 10.4161/cib.3.6.12844  1
2010 Alexander B, Warner-Schmidt J, Eriksson T, Tamminga C, Arango-Lievano M, Arango-Llievano M, Ghose S, Vernov M, Stavarache M, Stavarche M, Musatov S, Flajolet M, Svenningsson P, Greengard P, Kaplitt MG. Reversal of depressed behaviors in mice by p11 gene therapy in the nucleus accumbens. Science Translational Medicine. 2: 54ra76. PMID 20962330 DOI: 10.1126/scitranslmed.3001079  1
2010 Paillé V, Picconi B, Bagetta V, Ghiglieri V, Sgobio C, Di Filippo M, Viscomi MT, Giampà C, Fusco FR, Gardoni F, Bernardi G, Greengard P, Di Luca M, Calabresi P. Distinct levels of dopamine denervation differentially alter striatal synaptic plasticity and NMDA receptor subunit composition. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 30: 14182-93. PMID 20962239 DOI: 10.1523/JNEUROSCI.2149-10.2010  1
2010 Zhang Y, Kurup P, Xu J, Carty N, Fernandez SM, Nygaard HB, Pittenger C, Greengard P, Strittmatter SM, Nairn AC, Lombroso PJ. Genetic reduction of striatal-enriched tyrosine phosphatase (STEP) reverses cognitive and cellular deficits in an Alzheimer's disease mouse model. Proceedings of the National Academy of Sciences of the United States of America. 107: 19014-9. PMID 20956308 DOI: 10.1073/pnas.1013543107  1
2010 Fichter KM, Flajolet M, Greengard P, Vu TQ. Kinetics of G-protein-coupled receptor endosomal trafficking pathways revealed by single quantum dots. Proceedings of the National Academy of Sciences of the United States of America. 107: 18658-63. PMID 20940319 DOI: 10.1073/pnas.1013763107  1
2010 Flajolet M, Wang H, Greengard P. [mGluR5: a receptor at the therapeutic crossroad?]. MéDecine Sciences : M/S. 26: 678-80. PMID 20819696 DOI: 10.1051/medsci/2010268-9678  1
2010 He G, Luo W, Li P, Remmers C, Netzer WJ, Hendrick J, Bettayeb K, Flajolet M, Gorelick F, Wennogle LP, Greengard P. Gamma-secretase activating protein is a therapeutic target for Alzheimer's disease. Nature. 467: 95-8. PMID 20811458 DOI: 10.1038/nature09325  1
2010 Bateup HS, Santini E, Shen W, Birnbaum S, Valjent E, Surmeier DJ, Fisone G, Nestler EJ, Greengard P. Distinct subclasses of medium spiny neurons differentially regulate striatal motor behaviors. Proceedings of the National Academy of Sciences of the United States of America. 107: 14845-50. PMID 20682746 DOI: 10.1073/pnas.1009874107  1
2010 Bendor J, Lizardi-Ortiz JE, Westphalen RI, Brandstetter M, Hemmings HC, Sulzer D, Flajolet M, Greengard P. AGAP1/AP-3-dependent endocytic recycling of M5 muscarinic receptors promotes dopamine release. The Embo Journal. 29: 2813-26. PMID 20664521 DOI: 10.1038/emboj.2010.154  1
2010 Schaefer A, Im HI, Venø MT, Fowler CD, Min A, Intrator A, Kjems J, Kenny PJ, O'Carroll D, Greengard P. Argonaute 2 in dopamine 2 receptor-expressing neurons regulates cocaine addiction. The Journal of Experimental Medicine. 207: 1843-51. PMID 20643829 DOI: 10.1084/jem.20100451  1
2010 Warner-Schmidt JL, Chen EY, Zhang X, Marshall JJ, Morozov A, Svenningsson P, Greengard P. A role for p11 in the antidepressant action of brain-derived neurotrophic factor. Biological Psychiatry. 68: 528-35. PMID 20591415 DOI: 10.1016/j.biopsych.2010.04.029  1
2010 Netzer WJ, Powell C, Nong Y, Blundell J, Wong L, Duff K, Flajolet M, Greengard P. Lowering beta-amyloid levels rescues learning and memory in a Down syndrome mouse model. Plos One. 5: e10943. PMID 20532168 DOI: 10.1371/journal.pone.0010943  1
2010 Hemmings HC, Greengard P. Positively active: how local anesthetics work. Anesthesiology. 113: 250-2. PMID 20526177 DOI: 10.1097/ALN.0b013e3181e32e84  1
2010 Kurup P, Zhang Y, Xu J, Venkitaramani DV, Haroutunian V, Greengard P, Nairn AC, Lombroso PJ. Abeta-mediated NMDA receptor endocytosis in Alzheimer's disease involves ubiquitination of the tyrosine phosphatase STEP61. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 30: 5948-57. PMID 20427654 DOI: 10.1523/JNEUROSCI.0157-10.2010  1
2010 Ceglia I, Kim Y, Nairn AC, Greengard P. Signaling pathways controlling the phosphorylation state of WAVE1, a regulator of actin polymerization. Journal of Neurochemistry. 114: 182-90. PMID 20403076 DOI: 10.1111/j.1471-4159.2010.06743.x  1
2010 Hara M, Fukui R, Hieda E, Kuroiwa M, Bateup HS, Kano T, Greengard P, Nishi A. Role of adrenoceptors in the regulation of dopamine/DARPP-32 signaling in neostriatal neurons. Journal of Neurochemistry. 113: 1046-59. PMID 20236221 DOI: 10.1111/j.1471-4159.2010.06668.x  1
2010 Egeland M, Warner-Schmidt J, Greengard P, Svenningsson P. Neurogenic effects of fluoxetine are attenuated in p11 (S100A10) knockout mice. Biological Psychiatry. 67: 1048-56. PMID 20227680 DOI: 10.1016/j.biopsych.2010.01.024  1
2010 Zhou M, Rebholz H, Brocia C, Warner-Schmidt JL, Fienberg AA, Nairn AC, Greengard P, Flajolet M. Forebrain overexpression of CK1delta leads to down-regulation of dopamine receptors and altered locomotor activity reminiscent of ADHD. Proceedings of the National Academy of Sciences of the United States of America. 107: 4401-6. PMID 20145109 DOI: 10.1073/pnas.0915173107  1
2010 Zhang Y, Chen K, Baron M, Teylan MA, Kim Y, Song Z, Greengard P, Wong ST. A neurocomputational method for fully automated 3D dendritic spine detection and segmentation of medium-sized spiny neurons. Neuroimage. 50: 1472-84. PMID 20100579 DOI: 10.1016/j.neuroimage.2010.01.048  1
2010 Maze I, Covington HE, Dietz DM, LaPlant Q, Renthal W, Russo SJ, Mechanic M, Mouzon E, Neve RL, Haggarty SJ, Ren Y, Sampath SC, Hurd YL, Greengard P, Tarakhovsky A, et al. Essential role of the histone methyltransferase G9a in cocaine-induced plasticity. Science (New York, N.Y.). 327: 213-6. PMID 20056891 DOI: 10.1126/science.1179438  1
2010 Valjent E, Bertran-Gonzalez J, Aubier B, Greengard P, Hervé D, Girault JA. Mechanisms of locomotor sensitization to drugs of abuse in a two-injection protocol. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 35: 401-15. PMID 19759531 DOI: 10.1038/npp.2009.143  1
2009 Wang H, Westin L, Nong Y, Birnbaum S, Bendor J, Brismar H, Nestler E, Aperia A, Flajolet M, Greengard P. Norbin is an endogenous regulator of metabotropic glutamate receptor 5 signaling. Science (New York, N.Y.). 326: 1554-7. PMID 20007903 DOI: 10.1126/science.1178496  1
2009 Schaefer A, Sampath SC, Intrator A, Min A, Gertler TS, Surmeier DJ, Tarakhovsky A, Greengard P. Control of cognition and adaptive behavior by the GLP/G9a epigenetic suppressor complex. Neuron. 64: 678-91. PMID 20005824 DOI: 10.1016/j.neuron.2009.11.019  1
2009 Zhang YW, Liu S, Zhang X, Li WB, Chen Y, Huang X, Sun L, Luo W, Netzer WJ, Threadgill R, Wiegand G, Wang R, Cohen SN, Greengard P, Liao FF, et al. A functional mouse retroposed gene Rps23r1 reduces Alzheimer's beta-amyloid levels and tau phosphorylation. Neuron. 64: 328-40. PMID 19914182 DOI: 10.1016/j.neuron.2009.08.036  1
2009 Rebholz H, Nishi A, Liebscher S, Nairn AC, Flajolet M, Greengard P. CK2 negatively regulates Galphas signaling. Proceedings of the National Academy of Sciences of the United States of America. 106: 14096-101. PMID 19666609 DOI: 10.1073/pnas.0906857106  1
2009 Hansen C, Howlin J, Tengholm A, Dyachok O, Vogel WF, Nairn AC, Greengard P, Andersson T. Wnt-5a-induced phosphorylation of DARPP-32 inhibits breast cancer cell migration in a CREB-dependent manner. The Journal of Biological Chemistry. 284: 27533-43. PMID 19651774 DOI: 10.1074/jbc.M109.048884  0.4
2009 Santini E, Heiman M, Greengard P, Valjent E, Fisone G. Inhibition of mTOR signaling in Parkinson's disease prevents L-DOPA-induced dyskinesia. Science Signaling. 2: ra36. PMID 19622833 DOI: 10.1126/scisignal.2000308  1
2009 Tekinay AB, Nong Y, Miwa JM, Lieberam I, Ibanez-Tallon I, Greengard P, Heintz N. A role for LYNX2 in anxiety-related behavior. Proceedings of the National Academy of Sciences of the United States of America. 106: 4477-82. PMID 19246390 DOI: 10.1073/pnas.0813109106  1
2009 McAvoy T, Zhou MM, Greengard P, Nairn AC. Phosphorylation of Rap1GAP, a striatally enriched protein, by protein kinase A controls Rap1 activity and dendritic spine morphology. Proceedings of the National Academy of Sciences of the United States of America. 106: 3531-6. PMID 19218462 DOI: 10.1073/pnas.0813263106  1
2009 Endo S, Shutoh F, Dinh TL, Okamoto T, Ikeda T, Suzuki M, Kawahara S, Yanagihara D, Sato Y, Yamada K, Sakamoto T, Kirino Y, Hartell NA, Yamaguchi K, Itohara S, ... ... Greengard P, et al. Dual involvement of G-substrate in motor learning revealed by gene deletion. Proceedings of the National Academy of Sciences of the United States of America. 106: 3525-30. PMID 19218432 DOI: 10.1073/pnas.0813341106  1
2009 Warner-Schmidt JL, Flajolet M, Maller A, Chen EY, Qi H, Svenningsson P, Greengard P. Role of p11 in cellular and behavioral effects of 5-HT4 receptor stimulation. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 29: 1937-46. PMID 19211900 DOI: 10.1523/JNEUROSCI.5343-08.2009  1
2009 Kim Y, Teylan MA, Baron M, Sands A, Nairn AC, Greengard P. Methylphenidate-induced dendritic spine formation and DeltaFosB expression in nucleus accumbens. Proceedings of the National Academy of Sciences of the United States of America. 106: 2915-20. PMID 19202072 DOI: 10.1073/pnas.0813179106  1
2009 Santini E, Alcacer C, Cacciatore S, Heiman M, Hervé D, Greengard P, Girault JA, Valjent E, Fisone G. L-DOPA activates ERK signaling and phosphorylates histone H3 in the striatonigral medium spiny neurons of hemiparkinsonian mice. Journal of Neurochemistry. 108: 621-33. PMID 19187092 DOI: 10.1111/j.1471-4159.2008.05831.x  1
2009 Bertran-Gonzalez J, Håkansson K, Borgkvist A, Irinopoulou T, Brami-Cherrier K, Usiello A, Greengard P, Hervé D, Girault JA, Valjent E, Fisone G. Histone H3 phosphorylation is under the opposite tonic control of dopamine D2 and adenosine A2A receptors in striatopallidal neurons. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 34: 1710-20. PMID 19158668 DOI: 10.1038/npp.2008.228  1
2009 da Cruz e Silva OA, Rebelo S, Vieira SI, Gandy S, da Cruz e Silva EF, Greengard P. Enhanced generation of Alzheimer's amyloid-beta following chronic exposure to phorbol ester correlates with differential effects on alpha and epsilon isozymes of protein kinase C. Journal of Neurochemistry. 108: 319-30. PMID 19012746 DOI: 10.1111/j.1471-4159.2008.05770.x  1
2008 Meyer DA, Richer E, Benkovic SA, Hayashi K, Kansy JW, Hale CF, Moy LY, Kim Y, O'Callaghan JP, Tsai LH, Greengard P, Nairn AC, Cowan CW, Miller DB, Antich P, et al. Striatal dysregulation of Cdk5 alters locomotor responses to cocaine, motor learning, and dendritic morphology. Proceedings of the National Academy of Sciences of the United States of America. 105: 18561-6. PMID 19017804 DOI: 10.1073/pnas.0806078105  1
2008 Lagace DC, Benavides DR, Kansy JW, Mapelli M, Greengard P, Bibb JA, Eisch AJ. Cdk5 is essential for adult hippocampal neurogenesis. Proceedings of the National Academy of Sciences of the United States of America. 105: 18567-71. PMID 19017796 DOI: 10.1073/pnas.0810137105  1
2008 Doyle JP, Dougherty JD, Heiman M, Schmidt EF, Stevens TR, Ma G, Bupp S, Shrestha P, Shah RD, Doughty ML, Gong S, Greengard P, Heintz N. Application of a translational profiling approach for the comparative analysis of CNS cell types. Cell. 135: 749-62. PMID 19013282 DOI: 10.1016/j.cell.2008.10.029  1
2008 Heiman M, Schaefer A, Gong S, Peterson JD, Day M, Ramsey KE, Suárez-Fariñas M, Schwarz C, Stephan DA, Surmeier DJ, Greengard P, Heintz N. A translational profiling approach for the molecular characterization of CNS cell types. Cell. 135: 738-48. PMID 19013281 DOI: 10.1016/j.cell.2008.10.028  1
2008 Flajolet M, Wang Z, Futter M, Shen W, Nuangchamnong N, Bendor J, Wallach I, Nairn AC, Surmeier DJ, Greengard P. FGF acts as a co-transmitter through adenosine A(2A) receptor to regulate synaptic plasticity. Nature Neuroscience. 11: 1402-9. PMID 18953346 DOI: 10.1038/nn.2216  1
2008 Gitler D, Cheng Q, Greengard P, Augustine GJ. Synapsin IIa controls the reserve pool of glutamatergic synaptic vesicles. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 28: 10835-43. PMID 18945891 DOI: 10.1523/JNEUROSCI.0924-08.2008  1
2008 Nishi A, Kuroiwa M, Miller DB, O'Callaghan JP, Bateup HS, Shuto T, Sotogaku N, Fukuda T, Heintz N, Greengard P, Snyder GL. Distinct roles of PDE4 and PDE10A in the regulation of cAMP/PKA signaling in the striatum. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 28: 10460-71. PMID 18923023 DOI: 10.1523/JNEUROSCI.2518-08.2008  1
2008 Pulipparacharuvil S, Renthal W, Hale CF, Taniguchi M, Xiao G, Kumar A, Russo SJ, Sikder D, Dewey CM, Davis MM, Greengard P, Nairn AC, Nestler EJ, Cowan CW. Cocaine regulates MEF2 to control synaptic and behavioral plasticity. Neuron. 59: 621-33. PMID 18760698 DOI: 10.1016/j.neuron.2008.06.020  1
2008 Oumata N, Bettayeb K, Ferandin Y, Demange L, Lopez-Giral A, Goddard ML, Myrianthopoulos V, Mikros E, Flajolet M, Greengard P, Meijer L, Galons H. Roscovitine-derived, dual-specificity inhibitors of cyclin-dependent kinases and casein kinases 1. Journal of Medicinal Chemistry. 51: 5229-42. PMID 18698753 DOI: 10.1021/jm800109e  1
2008 Shen W, Flajolet M, Greengard P, Surmeier DJ. Dichotomous dopaminergic control of striatal synaptic plasticity. Science (New York, N.Y.). 321: 848-51. PMID 18687967 DOI: 10.1126/science.1160575  1
2008 Bateup HS, Svenningsson P, Kuroiwa M, Gong S, Nishi A, Heintz N, Greengard P. Cell type-specific regulation of DARPP-32 phosphorylation by psychostimulant and antipsychotic drugs. Nature Neuroscience. 11: 932-9. PMID 18622401 DOI: 10.1038/nn.2153  1
2008 Stipanovich A, Valjent E, Matamales M, Nishi A, Ahn JH, Maroteaux M, Bertran-Gonzalez J, Brami-Cherrier K, Enslen H, Corbillé AG, Filhol O, Nairn AC, Greengard P, Hervé D, Girault JA. A phosphatase cascade by which rewarding stimuli control nucleosomal response. Nature. 453: 879-84. PMID 18496528 DOI: 10.1038/nature06994  1
2008 Charlton JJ, Allen PB, Psifogeorgou K, Chakravarty S, Gomes I, Neve RL, Devi LA, Greengard P, Nestler EJ, Zachariou V. Multiple actions of spinophilin regulate mu opioid receptor function. Neuron. 58: 238-47. PMID 18439408 DOI: 10.1016/j.neuron.2008.02.006  1
2008 Muly EC, Nairn AC, Greengard P, Rainnie DG. Subcellular distribution of the Rho-GEF Lfc in primate prefrontal cortex: effect of neuronal activation. The Journal of Comparative Neurology. 508: 927-39. PMID 18399541 DOI: 10.1002/cne.21703  1
2008 O'Sullivan GJ, Dunleavy M, Hakansson K, Clementi M, Kinsella A, Croke DT, Drago J, Fienberg AA, Greengard P, Sibley DR, Fisone G, Henshall DC, Waddington JL. Dopamine D1 vs D5 receptor-dependent induction of seizures in relation to DARPP-32, ERK1/2 and GluR1-AMPA signalling. Neuropharmacology. 54: 1051-61. PMID 18367215 DOI: 10.1016/j.neuropharm.2008.02.011  1
2008 Sung JY, Engmann O, Teylan MA, Nairn AC, Greengard P, Kim Y. WAVE1 controls neuronal activity-induced mitochondrial distribution in dendritic spines. Proceedings of the National Academy of Sciences of the United States of America. 105: 3112-6. PMID 18287015 DOI: 10.1073/pnas.0712180105  1
2008 Kao HT, Li P, Chao HM, Janoschka S, Pham K, Feng J, Mcewen BS, Greengard P, Pieribone VA, Porton B. Early involvement of synapsin III in neural progenitor cell development in the adult hippocampus. The Journal of Comparative Neurology. 507: 1860-70. PMID 18271024 DOI: 10.1002/cne.21643  1
2008 Zhang X, Andren PE, Greengard P, Svenningsson P. Evidence for a role of the 5-HT1B receptor and its adaptor protein, p11, in L-DOPA treatment of an animal model of Parkinsonism. Proceedings of the National Academy of Sciences of the United States of America. 105: 2163-8. PMID 18256188 DOI: 10.1073/pnas.0711839105  1
2008 Borgkvist A, Marcellino D, Fuxe K, Greengard P, Fisone G. Regulation of DARPP-32 phosphorylation by Delta9-tetrahydrocannabinol. Neuropharmacology. 54: 31-5. PMID 17686497 DOI: 10.1016/j.neuropharm.2007.06.025  1
2007 Svenningsson P, Bateup H, Qi H, Takamiya K, Huganir RL, Spedding M, Roth BL, McEwen BS, Greengard P. Involvement of AMPA receptor phosphorylation in antidepressant actions with special reference to tianeptine. The European Journal of Neuroscience. 26: 3509-17. PMID 18088278 DOI: 10.1111/j.1460-9568.2007.05952.x  1
2007 Kitaoka S, Furuyashiki T, Nishi A, Shuto T, Koyasu S, Matsuoka T, Miyasaka M, Greengard P, Narumiya S. Prostaglandin E2 acts on EP1 receptor and amplifies both dopamine D1 and D2 receptor signaling in the striatum. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 27: 12900-7. PMID 18032663 DOI: 10.1523/JNEUROSCI.3257-07.2007  1
2007 Barbano PE, Spivak M, Flajolet M, Nairn AC, Greengard P, Greengard L. A mathematical tool for exploring the dynamics of biological networks. Proceedings of the National Academy of Sciences of the United States of America. 104: 19169-74. PMID 18032599 DOI: 10.1073/pnas.0709955104  1
2007 Schaefer A, O'Carroll D, Tan CL, Hillman D, Sugimori M, Llinas R, Greengard P. Cerebellar neurodegeneration in the absence of microRNAs. The Journal of Experimental Medicine. 204: 1553-8. PMID 17606634 DOI: 10.1084/jem.20070823  1
2007 Santini E, Valjent E, Usiello A, Carta M, Borgkvist A, Girault JA, Hervé D, Greengard P, Fisone G. Critical involvement of cAMP/DARPP-32 and extracellular signal-regulated protein kinase signaling in L-DOPA-induced dyskinesia. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 27: 6995-7005. PMID 17596448 DOI: 10.1523/JNEUROSCI.0852-07.2007  1
2007 Siksou L, Rostaing P, Lechaire JP, Boudier T, Ohtsuka T, Fejtová A, Kao HT, Greengard P, Gundelfinger ED, Triller A, Marty S. Three-dimensional architecture of presynaptic terminal cytomatrix. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 27: 6868-77. PMID 17596435 DOI: 10.1523/JNEUROSCI.1773-07.2007  1
2007 Ahn JH, Sung JY, McAvoy T, Nishi A, Janssens V, Goris J, Greengard P, Nairn AC. The B''/PR72 subunit mediates Ca2+-dependent dephosphorylation of DARPP-32 by protein phosphatase 2A. Proceedings of the National Academy of Sciences of the United States of America. 104: 9876-81. PMID 17535922 DOI: 10.1073/pnas.0703589104  1
2007 Hawasli AH, Benavides DR, Nguyen C, Kansy JW, Hayashi K, Chambon P, Greengard P, Powell CM, Cooper DC, Bibb JA. Cyclin-dependent kinase 5 governs learning and synaptic plasticity via control of NMDAR degradation. Nature Neuroscience. 10: 880-6. PMID 17529984 DOI: 10.1038/nn1914  1
2007 Luo W, Dou F, Rodina A, Chip S, Kim J, Zhao Q, Moulick K, Aguirre J, Wu N, Greengard P, Chiosis G. Roles of heat-shock protein 90 in maintaining and facilitating the neurodegenerative phenotype in tauopathies. Proceedings of the National Academy of Sciences of the United States of America. 104: 9511-6. PMID 17517623 DOI: 10.1073/pnas.0701055104  1
2007 Wang X, Zeng W, Kim MS, Allen PB, Greengard P, Muallem S. Spinophilin/neurabin reciprocally regulate signaling intensity by G protein-coupled receptors. The Embo Journal. 26: 2768-76. PMID 17464283 DOI: 10.1038/sj.emboj.7601701  1
2007 Sahlin C, Lord A, Magnusson K, Englund H, Almeida CG, Greengard P, Nyberg F, Gouras GK, Lannfelt L, Nilsson LN. The Arctic Alzheimer mutation favors intracellular amyloid-beta production by making amyloid precursor protein less available to alpha-secretase. Journal of Neurochemistry. 101: 854-62. PMID 17448150 DOI: 10.1111/j.1471-4159.2006.04443.x  1
2007 Svenningsson P, Tzavara ET, Qi H, Carruthers R, Witkin JM, Nomikos GG, Greengard P. Biochemical and behavioral evidence for antidepressant-like effects of 5-HT6 receptor stimulation. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 27: 4201-9. PMID 17428998 DOI: 10.1523/JNEUROSCI.3110-06.2007  1
2007 Flajolet M, He G, Heiman M, Lin A, Nairn AC, Greengard P. Regulation of Alzheimer's disease amyloid-beta formation by casein kinase I. Proceedings of the National Academy of Sciences of the United States of America. 104: 4159-64. PMID 17360493 DOI: 10.1073/pnas.0611236104  1
2007 Ahn JH, McAvoy T, Rakhilin SV, Nishi A, Greengard P, Nairn AC. Protein kinase A activates protein phosphatase 2A by phosphorylation of the B56delta subunit. Proceedings of the National Academy of Sciences of the United States of America. 104: 2979-84. PMID 17301223 DOI: 10.1073/pnas.0611532104  1
2007 Borgkvist A, Usiello A, Greengard P, Fisone G. Activation of the cAMP/PKA/DARPP-32 signaling pathway is required for morphine psychomotor stimulation but not for morphine reward. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 32: 1995-2003. PMID 17251906 DOI: 10.1038/sj.npp.1301321  1
2007 Svenningsson P, Greengard P. p11 (S100A10)--an inducible adaptor protein that modulates neuronal functions. Current Opinion in Pharmacology. 7: 27-32. PMID 17085073 DOI: 10.1016/j.coph.2006.10.001  1
2006 Liu W, Yuen EY, Allen PB, Feng J, Greengard P, Yan Z. Adrenergic modulation of NMDA receptors in prefrontal cortex is differentially regulated by RGS proteins and spinophilin. Proceedings of the National Academy of Sciences of the United States of America. 103: 18338-43. PMID 17101972 DOI: 10.1073/pnas.0604560103  1
2006 Hansen C, Greengard P, Nairn AC, Andersson T, Vogel WF. Phosphorylation of DARPP-32 regulates breast cancer cell migration downstream of the receptor tyrosine kinase DDR1. Experimental Cell Research. 312: 4011-8. PMID 17027969 DOI: 10.1016/j.yexcr.2006.09.003  1
2006 Aperia A, Greengard P. Dopamine receptor response to NMDA stimulation. The American Journal of Psychiatry. 163: 1682. PMID 17012674 DOI: 10.1176/appi.ajp.163.10.1682  1
2006 Yan L, Bobula JM, Svenningsson P, Greengard P, Silver R. DARPP-32 involvement in the photic pathway of the circadian system. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 26: 9434-8. PMID 16971527 DOI: 10.1523/JNEUROSCI.2538-06.2006  1
2006 Kim Y, Sung JY, Ceglia I, Lee KW, Ahn JH, Halford JM, Kim AM, Kwak SP, Park JB, Ho Ryu S, Schenck A, Bardoni B, Scott JD, Nairn AC, Greengard P. Phosphorylation of WAVE1 regulates actin polymerization and dendritic spine morphology. Nature. 442: 814-7. PMID 16862120 DOI: 10.1038/nature04976  1
2006 Venton BJ, Seipel AT, Phillips PE, Wetsel WC, Gitler D, Greengard P, Augustine GJ, Wightman RM. Cocaine increases dopamine release by mobilization of a synapsin-dependent reserve pool. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 26: 3206-9. PMID 16554471 DOI: 10.1523/JNEUROSCI.4901-04.2006  1
2006 Rogers JP, Beuscher AE, Flajolet M, McAvoy T, Nairn AC, Olson AJ, Greengard P. Discovery of protein phosphatase 2C inhibitors by virtual screening. Journal of Medicinal Chemistry. 49: 1658-67. PMID 16509582 DOI: 10.1021/jm051033y  1
2006 Lee KW, Kim Y, Kim AM, Helmin K, Nairn AC, Greengard P. Cocaine-induced dendritic spine formation in D1 and D2 dopamine receptor-containing medium spiny neurons in nucleus accumbens. Proceedings of the National Academy of Sciences of the United States of America. 103: 3399-404. PMID 16492766 DOI: 10.1073/pnas.0511244103  1
2006 Cai D, Netzer WJ, Zhong M, Lin Y, Du G, Frohman M, Foster DA, Sisodia SS, Xu H, Gorelick FS, Greengard P. Presenilin-1 uses phospholipase D1 as a negative regulator of beta-amyloid formation. Proceedings of the National Academy of Sciences of the United States of America. 103: 1941-6. PMID 16449386 DOI: 10.1073/pnas.0510708103  1
2006 Cai D, Zhong M, Wang R, Netzer WJ, Shields D, Zheng H, Sisodia SS, Foster DA, Gorelick FS, Xu H, Greengard P. Phospholipase D1 corrects impaired betaAPP trafficking and neurite outgrowth in familial Alzheimer's disease-linked presenilin-1 mutant neurons. Proceedings of the National Academy of Sciences of the United States of America. 103: 1936-40. PMID 16449385 DOI: 10.1073/pnas.0510710103  1
2006 Scott L, Zelenin S, Malmersjö S, Kowalewski JM, Markus EZ, Nairn AC, Greengard P, Brismar H, Aperia A. Allosteric changes of the NMDA receptor trap diffusible dopamine 1 receptors in spines. Proceedings of the National Academy of Sciences of the United States of America. 103: 762-7. PMID 16407151 DOI: 10.1073/pnas.0505557103  1
2006 Svenningsson P, Chergui K, Rachleff I, Flajolet M, Zhang X, El Yacoubi M, Vaugeois JM, Nomikos GG, Greengard P. Alterations in 5-HT1B receptor function by p11 in depression-like states. Science (New York, N.Y.). 311: 77-80. PMID 16400147 DOI: 10.1126/science.1117571  1
2006 Håkansson K, Galdi S, Hendrick J, Snyder G, Greengard P, Fisone G. Regulation of phosphorylation of the GluR1 AMPA receptor by dopamine D2 receptors. Journal of Neurochemistry. 96: 482-8. PMID 16336634 DOI: 10.1111/j.1471-4159.2005.03558.x  1
2006 Zachariou V, Sgambato-Faure V, Sasaki T, Svenningsson P, Berton O, Fienberg AA, Nairn AC, Greengard P, Nestler EJ. Phosphorylation of DARPP-32 at Threonine-34 is required for cocaine action. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 31: 555-62. PMID 16123776 DOI: 10.1038/sj.npp.1300832  1
2005 Svenningsson P, Nairn AC, Greengard P. DARPP-32 mediates the actions of multiple drugs of abuse. The Aaps Journal. 7: E353-60. PMID 16353915 DOI: 10.1208/aapsj070235  1
2005 Jin M, Bateup H, Padovan JC, Greengard P, Nairn AC, Chait BT. Quantitative analysis of protein phosphorylation in mouse brain by hypothesis-driven multistage mass spectrometry. Analytical Chemistry. 77: 7845-51. PMID 16351129 DOI: 10.1021/ac051519m  1
2005 Uematsu K, Futter M, Hsieh-Wilson LC, Higashi H, Maeda H, Nairn AC, Greengard P, Nishi A. Regulation of spinophilin Ser94 phosphorylation in neostriatal neurons involves both DARPP-32-dependent and independent pathways. Journal of Neurochemistry. 95: 1642-52. PMID 16300646 DOI: 10.1111/j.1471-4159.2005.03491.x  1
2005 Almeida CG, Tampellini D, Takahashi RH, Greengard P, Lin MT, Snyder EM, Gouras GK. Beta-amyloid accumulation in APP mutant neurons reduces PSD-95 and GluR1 in synapses. Neurobiology of Disease. 20: 187-98. PMID 16242627 DOI: 10.1016/j.nbd.2005.02.008  1
2005 Andersson M, Usiello A, Borgkvist A, Pozzi L, Dominguez C, Fienberg AA, Svenningsson P, Fredholm BB, Borrelli E, Greengard P, Fisone G. Cannabinoid action depends on phosphorylation of dopamine- and cAMP-regulated phosphoprotein of 32 kDa at the protein kinase A site in striatal projection neurons. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 25: 8432-8. PMID 16162925 DOI: 10.1523/JNEUROSCI.1289-05.2005  1
2005 Hamada M, Hendrick JP, Ryan GR, Kuroiwa M, Higashi H, Tanaka M, Nairn AC, Greengard P, Nishi A. Nicotine regulates DARPP-32 (dopamine- and cAMP-regulated phosphoprotein of 32 kDa) phosphorylation at multiple sites in neostriatal neurons. The Journal of Pharmacology and Experimental Therapeutics. 315: 872-8. PMID 16040813 DOI: 10.1124/jpet.105.090852  1
2005 Snyder EM, Nong Y, Almeida CG, Paul S, Moran T, Choi EY, Nairn AC, Salter MW, Lombroso PJ, Gouras GK, Greengard P. Regulation of NMDA receptor trafficking by amyloid-beta. Nature Neuroscience. 8: 1051-8. PMID 16025111 DOI: 10.1038/nn1503  1
2005 Chergui K, Svenningsson P, Greengard P. Physiological role for casein kinase 1 in glutamatergic synaptic transmission. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 25: 6601-9. PMID 16014721 DOI: 10.1523/JNEUROSCI.1082-05.2005  1
2005 Ryan XP, Alldritt J, Svenningsson P, Allen PB, Wu GY, Nairn AC, Greengard P. The Rho-specific GEF Lfc interacts with neurabin and spinophilin to regulate dendritic spine morphology. Neuron. 47: 85-100. PMID 15996550 DOI: 10.1016/j.neuron.2005.05.013  1
2005 Stenh C, Englund H, Lord A, Johansson AS, Almeida CG, Gellerfors P, Greengard P, Gouras GK, Lannfelt L, Nilsson LN. Amyloid-beta oligomers are inefficiently measured by enzyme-linked immunosorbent assay. Annals of Neurology. 58: 147-50. PMID 15984012 DOI: 10.1002/ana.20524  1
2005 Wang X, Zeng W, Soyombo AA, Tang W, Ross EM, Barnes AP, Milgram SL, Penninger JM, Allen PB, Greengard P, Muallem S. Spinophilin regulates Ca2+ signalling by binding the N-terminal domain of RGS2 and the third intracellular loop of G-protein-coupled receptors. Nature Cell Biology. 7: 405-11. PMID 15793568 DOI: 10.1038/ncb1237  1
2005 Bordelon JR, Smith Y, Nairn AC, Colbran RJ, Greengard P, Muly EC. Differential localization of protein phosphatase-1alpha, beta and gamma1 isoforms in primate prefrontal cortex. Cerebral Cortex (New York, N.Y. : 1991). 15: 1928-37. PMID 15758197 DOI: 10.1093/cercor/bhi070  1
2005 Hilfiker S, Benfenati F, Doussau F, Nairn AC, Czernik AJ, Augustine GJ, Greengard P. Structural domains involved in the regulation of transmitter release by synapsins. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 25: 2658-69. PMID 15758176 DOI: 10.1523/JNEUROSCI.4278-04.2005  1
2005 Futter M, Uematsu K, Bullock SA, Kim Y, Hemmings HC, Nishi A, Greengard P, Nairn AC. Phosphorylation of spinophilin by ERK and cyclin-dependent PK 5 (Cdk5). Proceedings of the National Academy of Sciences of the United States of America. 102: 3489-94. PMID 15728359 DOI: 10.1073/pnas.0409802102  1
2005 Brady AE, Wang Q, Allen PB, Rizzo M, Greengard P, Limbird LE. Alpha 2-adrenergic agonist enrichment of spinophilin at the cell surface involves beta gamma subunits of Gi proteins and is preferentially induced by the alpha 2A-subtype. Molecular Pharmacology. 67: 1690-6. PMID 15705742 DOI: 10.1124/mol.104.005215  1
2005 Takahashi S, Ohshima T, Cho A, Sreenath T, Iadarola MJ, Pant HC, Kim Y, Nairn AC, Brady RO, Greengard P, Kulkarni AB. Increased activity of cyclin-dependent kinase 5 leads to attenuation of cocaine-mediated dopamine signaling. Proceedings of the National Academy of Sciences of the United States of America. 102: 1737-42. PMID 15665076 DOI: 10.1073/pnas.0409456102  1
2005 Nishi A, Watanabe Y, Higashi H, Tanaka M, Nairn AC, Greengard P. Glutamate regulation of DARPP-32 phosphorylation in neostriatal neurons involves activation of multiple signaling cascades. Proceedings of the National Academy of Sciences of the United States of America. 102: 1199-204. PMID 15657149 DOI: 10.1073/pnas.0409138102  1
2005 Valjent E, Pascoli V, Svenningsson P, Paul S, Enslen H, Corvol JC, Stipanovich A, Caboche J, Lombroso PJ, Nairn AC, Greengard P, Hervé D, Girault JA. Regulation of a protein phosphatase cascade allows convergent dopamine and glutamate signals to activate ERK in the striatum. Proceedings of the National Academy of Sciences of the United States of America. 102: 491-6. PMID 15608059 DOI: 10.1073/pnas.0408305102  1
2004 Gitler D, Takagishi Y, Feng J, Ren Y, Rodriguiz RM, Wetsel WC, Greengard P, Augustine GJ. Different presynaptic roles of synapsins at excitatory and inhibitory synapses. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 24: 11368-80. PMID 15601943 DOI: 10.1523/JNEUROSCI.3795-04.2004  1
2004 Meijer L, Flajolet M, Greengard P. Pharmacological inhibitors of glycogen synthase kinase 3. Trends in Pharmacological Sciences. 25: 471-80. PMID 15559249 DOI: 10.1016/j.tips.2004.07.006  1
2004 Ouimet CC, Katona I, Allen P, Freund TF, Greengard P. Cellular and subcellular distribution of spinophilin, a PP1 regulatory protein that bundles F-actin in dendritic spines. The Journal of Comparative Neurology. 479: 374-88. PMID 15514983 DOI: 10.1002/cne.20313  1
2004 Nairn AC, Svenningsson P, Nishi A, Fisone G, Girault JA, Greengard P. The role of DARPP-32 in the actions of drugs of abuse. Neuropharmacology. 47: 14-23. PMID 15464122 DOI: 10.1016/j.neuropharm.2004.05.010  1
2004 Hamada M, Higashi H, Nairn AC, Greengard P, Nishi A. Differential regulation of dopamine D1 and D2 signaling by nicotine in neostriatal neurons. Journal of Neurochemistry. 90: 1094-103. PMID 15312165 DOI: 10.1111/j.1471-4159.2004.02574.x  1
2004 Giovedì S, Darchen F, Valtorta F, Greengard P, Benfenati F. Synapsin is a novel Rab3 effector protein on small synaptic vesicles. II. Functional effects of the Rab3A-synapsin I interaction. The Journal of Biological Chemistry. 279: 43769-79. PMID 15265868 DOI: 10.1074/jbc.M404168200  1
2004 Giovedì S, Vaccaro P, Valtorta F, Darchen F, Greengard P, Cesareni G, Benfenati F. Synapsin is a novel Rab3 effector protein on small synaptic vesicles. I. Identification and characterization of the synapsin I-Rab3 interactions in vitro and in intact nerve terminals. The Journal of Biological Chemistry. 279: 43760-8. PMID 15265865 DOI: 10.1074/jbc.M403293200  1
2004 Wang H, Luo WJ, Zhang YW, Li YM, Thinakaran G, Greengard P, Xu H. Presenilins and gamma-secretase inhibitors affect intracellular trafficking and cell surface localization of the gamma-secretase complex components. The Journal of Biological Chemistry. 279: 40560-6. PMID 15247291 DOI: 10.1074/jbc.M404345200  1
2004 Grossman SD, Futter M, Snyder GL, Allen PB, Nairn AC, Greengard P, Hsieh-Wilson LC. Spinophilin is phosphorylated by Ca2+/calmodulin-dependent protein kinase II resulting in regulation of its binding to F-actin. Journal of Neurochemistry. 90: 317-24. PMID 15228588 DOI: 10.1111/j.1471-4159.2004.02491.x  1
2004 Wang Q, Zhao J, Brady AE, Feng J, Allen PB, Lefkowitz RJ, Greengard P, Limbird LE. Spinophilin blocks arrestin actions in vitro and in vivo at G protein-coupled receptors. Science (New York, N.Y.). 304: 1940-4. PMID 15218143 DOI: 10.1126/science.1098274  1
2004 Muly EC, Allen P, Mazloom M, Aranbayeva Z, Greenfield AT, Greengard P. Subcellular distribution of neurabin immunolabeling in primate prefrontal cortex: comparison with spinophilin. Cerebral Cortex (New York, N.Y. : 1991). 14: 1398-407. PMID 15217898 DOI: 10.1093/cercor/bhh101  1
2004 Girault JA, Greengard P. The neurobiology of dopamine signaling. Archives of Neurology. 61: 641-4. PMID 15148138 DOI: 10.1001/archneur.61.5.641  1
2004 Nally RE, Kinsella A, Tighe O, Croke DT, Fienberg AA, Greengard P, Waddington JL. Ethologically based resolution of D2-like dopamine receptor agonist-versus antagonist-induced behavioral topography in dopamine- and adenosine 3',5'-monophosphate-regulated phosphoprotein of 32 kDa "knockout" mutants congenic on the C57BL/6 genetic background. The Journal of Pharmacology and Experimental Therapeutics. 310: 1281-7. PMID 15140917 DOI: 10.1124/jpet.104.068957  1
2004 Allen PB, Greenfield AT, Svenningsson P, Haspeslagh DC, Greengard P. Phactrs 1-4: A family of protein phosphatase 1 and actin regulatory proteins. Proceedings of the National Academy of Sciences of the United States of America. 101: 7187-92. PMID 15107502 DOI: 10.1073/pnas.0401673101  1
2004 Knockaert M, Blondel M, Bach S, Leost M, Elbi C, Hager GL, Nagy SR, Han D, Denison M, Ffrench M, Ryan XP, Magiatis P, Polychronopoulos P, Greengard P, Skaltsounis L, et al. Independent actions on cyclin-dependent kinases and aryl hydrocarbon receptor mediate the antiproliferative effects of indirubins. Oncogene. 23: 4400-12. PMID 15077192 DOI: 10.1038/sj.onc.1207535  1
2004 Gitler D, Xu Y, Kao HT, Lin D, Lim S, Feng J, Greengard P, Augustine GJ. Molecular determinants of synapsin targeting to presynaptic terminals. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 24: 3711-20. PMID 15071120 DOI: 10.1523/JNEUROSCI.5225-03.2004  1
2004 Chen G, Greengard P, Yan Z. Potentiation of NMDA receptor currents by dopamine D1 receptors in prefrontal cortex. Proceedings of the National Academy of Sciences of the United States of America. 101: 2596-600. PMID 14983054 DOI: 10.1073/pnas.0308618100  1
2004 Lin TH, Huang YC, Chin ML, Chen YC, Jeng HH, Lin FM, Shiao MS, Horiuchi A, Greengard P, Nairn AC, Huang HB. 1H, 15N, and 13C resonance assignments of DARPP-32 (dopamine and cAMP-regulated phosphoprotein, Mr. 32,000)--a protein inhibitor of protein phosphatase-1. Journal of Biomolecular Nmr. 28: 413-4. PMID 14872138 DOI: 10.1023/B:JNMR.0000015358.20495.b8  1
2004 Chergui K, Svenningsson P, Greengard P. Cyclin-dependent kinase 5 regulates dopaminergic and glutamatergic transmission in the striatum. Proceedings of the National Academy of Sciences of the United States of America. 101: 2191-6. PMID 14769920 DOI: 10.1073/pnas.0308652100  1
2004 Li C, Brake WG, Romeo RD, Dunlop JC, Gordon M, Buzescu R, Magarinos AM, Allen PB, Greengard P, Luine V, McEwen BS. Estrogen alters hippocampal dendritic spine shape and enhances synaptic protein immunoreactivity and spatial memory in female mice. Proceedings of the National Academy of Sciences of the United States of America. 101: 2185-90. PMID 14766964 DOI: 10.1073/pnas.0307313101  1
2004 Polychronopoulos P, Magiatis P, Skaltsounis AL, Myrianthopoulos V, Mikros E, Tarricone A, Musacchio A, Roe SM, Pearl L, Leost M, Greengard P, Meijer L. Structural basis for the synthesis of indirubins as potent and selective inhibitors of glycogen synthase kinase-3 and cyclin-dependent kinases. Journal of Medicinal Chemistry. 47: 935-46. PMID 14761195 DOI: 10.1021/jm031016d  1
2004 Svenningsson P, Nishi A, Fisone G, Girault JA, Nairn AC, Greengard P. DARPP-32: an integrator of neurotransmission. Annual Review of Pharmacology and Toxicology. 44: 269-96. PMID 14744247 DOI: 10.1146/annurev.pharmtox.44.101802.121415  1
2004 Tang Y, Janssen WG, Hao J, Roberts JA, McKay H, Lasley B, Allen PB, Greengard P, Rapp PR, Kordower JH, Hof PR, Morrison JH. Estrogen replacement increases spinophilin-immunoreactive spine number in the prefrontal cortex of female rhesus monkeys. Cerebral Cortex (New York, N.Y. : 1991). 14: 215-23. PMID 14704219 DOI: 10.1093/cercor/bhg121  1
2004 Sato N, Meijer L, Skaltsounis L, Greengard P, Brivanlou AH. Maintenance of pluripotency in human and mouse embryonic stem cells through activation of Wnt signaling by a pharmacological GSK-3-specific inhibitor. Nature Medicine. 10: 55-63. PMID 14702635 DOI: 10.1038/nm979  1
2004 Muly EC, Smith Y, Allen P, Greengard P. Subcellular distribution of spinophilin immunolabeling in primate prefrontal cortex: localization to and within dendritic spines. The Journal of Comparative Neurology. 469: 185-97. PMID 14694533 DOI: 10.1002/cne.11001  1
2003 Fukui R, Svenningsson P, Matsuishi T, Higashi H, Nairn AC, Greengard P, Nishi A. Effect of methylphenidate on dopamine/DARPP signalling in adult, but not young, mice. Journal of Neurochemistry. 87: 1391-401. PMID 14713295  1
2003 Meijer L, Skaltsounis AL, Magiatis P, Polychronopoulos P, Knockaert M, Leost M, Ryan XP, Vonica CA, Brivanlou A, Dajani R, Crovace C, Tarricone C, Musacchio A, Roe SM, Pearl L, ... Greengard P, et al. GSK-3-selective inhibitors derived from Tyrian purple indirubins. Chemistry & Biology. 10: 1255-66. PMID 14700633 DOI: 10.1016/j.chembiol.2003.11.010  1
2003 Watanabe T, da Cruz e Silva EF, Huang HB, Starkova N, Kwon YG, Horiuchi A, Greengard P, Nairn AC. Preparation and characterization of recombinant protein phosphatase 1. Methods in Enzymology. 366: 321-38. PMID 14674258  0.88
2003 Flajolet M, Rakhilin S, Wang H, Starkova N, Nuangchamnong N, Nairn AC, Greengard P. Protein phosphatase 2C binds selectively to and dephosphorylates metabotropic glutamate receptor 3. Proceedings of the National Academy of Sciences of the United States of America. 100: 16006-11. PMID 14663150 DOI: 10.1073/pnas.2136600100  1
2003 Svenningsson P, Tzavara ET, Carruthers R, Rachleff I, Wattler S, Nehls M, McKinzie DL, Fienberg AA, Nomikos GG, Greengard P. Diverse psychotomimetics act through a common signaling pathway. Science (New York, N.Y.). 302: 1412-5. PMID 14631045 DOI: 10.1126/science.1089681  1
2003 Snyder GL, Galdi S, Fienberg AA, Allen P, Nairn AC, Greengard P. Regulation of AMPA receptor dephosphorylation by glutamate receptor agonists. Neuropharmacology. 45: 703-13. PMID 14529709 DOI: 10.1016/S0028-3908(03)00319-8  1
2003 Netzer WJ, Dou F, Cai D, Veach D, Jean S, Li Y, Bornmann WG, Clarkson B, Xu H, Greengard P. Gleevec inhibits beta-amyloid production but not Notch cleavage. Proceedings of the National Academy of Sciences of the United States of America. 100: 12444-9. PMID 14523244 DOI: 10.1073/pnas.1534745100  1
2003 Hao J, Janssen WG, Tang Y, Roberts JA, McKay H, Lasley B, Allen PB, Greengard P, Rapp PR, Kordower JH, Hof PR, Morrison JH. Estrogen increases the number of spinophilin-immunoreactive spines in the hippocampus of young and aged female rhesus monkeys. The Journal of Comparative Neurology. 465: 540-50. PMID 12975814 DOI: 10.1002/cne.10837  1
2003 Pozzi L, HÃ¥kansson K, Usiello A, Borgkvist A, Lindskog M, Greengard P, Fisone G. Opposite regulation by typical and atypical anti-psychotics of ERK1/2, CREB and Elk-1 phosphorylation in mouse dorsal striatum. Journal of Neurochemistry. 86: 451-9. PMID 12871586 DOI: 10.1046/j.1471-4159.2003.01851.x  1
2003 Nally RE, McNamara FN, Clifford JJ, Kinsella A, Tighe O, Croke DT, Fienberg AA, Greengard P, Waddington JL. Topographical Assessment of Ethological and Dopamine Receptor Agonist-Induced Behavioral Phenotype in Mutants with Congenic DARPP-32 'Knockout'. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 28: 2055-63. PMID 12865890 DOI: 10.1038/sj.npp.1300259  0.72
2003 Sabo SL, Ikin AF, Buxbaum JD, Greengard P. The amyloid precursor protein and its regulatory protein, FE65, in growth cones and synapses in vitro and in vivo. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 23: 5407-15. PMID 12843239  1
2003 Bloom O, Evergren E, Tomilin N, Kjaerulff O, Löw P, Brodin L, Pieribone VA, Greengard P, Shupliakov O. Colocalization of synapsin and actin during synaptic vesicle recycling. The Journal of Cell Biology. 161: 737-47. PMID 12756235 DOI: 10.1083/jcb.200212140  1
2003 Brady AE, Wang Q, Colbran RJ, Allen PB, Greengard P, Limbird LE. Spinophilin stabilizes cell surface expression of alpha 2B-adrenergic receptors. The Journal of Biological Chemistry. 278: 32405-12. PMID 12738775 DOI: 10.1074/jbc.M304195200  1
2003 Chi P, Greengard P, Ryan TA. Synaptic vesicle mobilization is regulated by distinct synapsin I phosphorylation pathways at different frequencies. Neuron. 38: 69-78. PMID 12691665 DOI: 10.1016/S0896-6273(03)00151-X  1
2003 Picconi B, Centonze D, HÃ¥kansson K, Bernardi G, Greengard P, Fisone G, Cenci MA, Calabresi P. Loss of bidirectional striatal synaptic plasticity in L-DOPA-induced dyskinesia. Nature Neuroscience. 6: 501-6. PMID 12665799 DOI: 10.1038/nn1040  0.92
2003 Lindgren N, Usiello A, Goiny M, Haycock J, Erbs E, Greengard P, Hokfelt T, Borrelli E, Fisone G. Distinct roles of dopamine D2L and D2S receptor isoforms in the regulation of protein phosphorylation at presynaptic and postsynaptic sites. Proceedings of the National Academy of Sciences of the United States of America. 100: 4305-9. PMID 12651945 DOI: 10.1073/pnas.0730708100  0.92
2003 Kruse MS, Adachi S, Scott L, Holtbäck U, Greengard P, Aperia A, Brismar H. Recruitment of renal dopamine 1 receptors requires an intact microtubulin network. PflüGers Archiv : European Journal of Physiology. 445: 534-9. PMID 12634922 DOI: 10.1007/s00424-002-0899-5  0.6
2003 Dou F, Netzer WJ, Tanemura K, Li F, Hartl FU, Takashima A, Gouras GK, Greengard P, Xu H. Chaperones increase association of tau protein with microtubules. Proceedings of the National Academy of Sciences of the United States of America. 100: 721-6. PMID 12522269 DOI: 10.1073/pnas.242720499  1
2003 Cai D, Leem JY, Greenfield JP, Wang P, Kim BS, Wang R, Lopes KO, Kim SH, Zheng H, Greengard P, Sisodia SS, Thinakaran G, Xu H. Presenilin-1 regulates intracellular trafficking and cell surface delivery of beta-amyloid precursor protein. The Journal of Biological Chemistry. 278: 3446-54. PMID 12435726 DOI: 10.1074/jbc.M209065200  1
2003 Hsieh-Wilson LC, Benfenati F, Snyder GL, Allen PB, Nairn AC, Greengard P. Phosphorylation of spinophilin modulates its interaction with actin filaments. The Journal of Biological Chemistry. 278: 1186-94. PMID 12417592 DOI: 10.1074/jbc.M205754200  1
2002 Takahashi RH, Milner TA, Li F, Nam EE, Edgar MA, Yamaguchi H, Beal MF, Xu H, Greengard P, Gouras GK. Intraneuronal Alzheimer abeta42 accumulates in multivesicular bodies and is associated with synaptic pathology. The American Journal of Pathology. 161: 1869-79. PMID 12414533  1
2002 Pieribone VA, Porton B, Rendon B, Feng J, Greengard P, Kao HT. Expression of synapsin III in nerve terminals and neurogenic regions of the adult brain. The Journal of Comparative Neurology. 454: 105-14. PMID 12412137 DOI: 10.1002/cne.10417  1
2002 Shupliakov O, Bloom O, Gustafsson JS, Kjaerulff O, Low P, Tomilin N, Pieribone VA, Greengard P, Brodin L. Impaired recycling of synaptic vesicles after acute perturbation of the presynaptic actin cytoskeleton. Proceedings of the National Academy of Sciences of the United States of America. 99: 14476-81. PMID 12381791 DOI: 10.1073/pnas.212381799  1
2002 Grossman SD, Hsieh-Wilson LC, Allen PB, Nairn AC, Greengard P. The actin-binding domain of spinophilin is necessary and sufficient for targeting to dendritic spines. Neuromolecular Medicine. 2: 61-9. PMID 12230305 DOI: 10.1385/NMM:2:1:61  1
2002 Lindskog M, Svenningsson P, Pozzi L, Kim Y, Fienberg AA, Bibb JA, Fredholm BB, Nairn AC, Greengard P, Fisone G. Involvement of DARPP-32 phosphorylation in the stimulant action of caffeine. Nature. 418: 774-8. PMID 12181566 DOI: 10.1038/nature00817  1
2002 Menegon A, Verderio C, Leoni C, Benfenati F, Czernik AJ, Greengard P, Matteoli M, Valtorta F. Spatial and temporal regulation of Ca2+/calmodulin-dependent protein kinase II activity in developing neurons. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 22: 7016-26. PMID 12177199  1
2002 Albert KA, Hemmings HC, Adamo AI, Potkin SG, Akbarian S, Sandman CA, Cotman CW, Bunney WE, Greengard P. Evidence for decreased DARPP-32 in the prefrontal cortex of patients with schizophrenia. Archives of General Psychiatry. 59: 705-12. PMID 12150646  1
2002 Gasparini L, Netzer WJ, Greengard P, Xu H. Does insulin dysfunction play a role in Alzheimer's disease? Trends in Pharmacological Sciences. 23: 288-93. PMID 12084635 DOI: 10.1016/S0165-6147(02)02037-0  1
2002 Nishi A, Bibb JA, Matsuyama S, Hamada M, Higashi H, Nairn AC, Greengard P. Regulation of DARPP-32 dephosphorylation at PKA- and Cdk5-sites by NMDA and AMPA receptors: distinct roles of calcineurin and protein phosphatase-2A. Journal of Neurochemistry. 81: 832-41. PMID 12065642 DOI: 10.1046/j.1471-4159.2002.00876.x  1
2002 Feng J, Chi P, Blanpied TA, Xu Y, Magarinos AM, Ferreira A, Takahashi RH, Kao HT, McEwen BS, Ryan TA, Augustine GJ, Greengard P. Regulation of neurotransmitter release by synapsin III. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 22: 4372-80. PMID 12040043  1
2002 Yan Z, Chi P, Bibb JA, Ryan TA, Greengard P. Roscovitine: a novel regulator of P/Q-type calcium channels and transmitter release in central neurons. The Journal of Physiology. 540: 761-70. PMID 11986366 DOI: 10.1113/jphysiol.2001.013376  1
2002 Kao HT, Song HJ, Porton B, Ming GL, Hoh J, Abraham M, Czernik AJ, Pieribone VA, Poo MM, Greengard P. A protein kinase A-dependent molecular switch in synapsins regulates neurite outgrowth. Nature Neuroscience. 5: 431-7. PMID 11976703 DOI: 10.1038/nn840  1
2002 Zachariou V, Benoit-Marand M, Allen PB, Ingrassia P, Fienberg AA, Gonon F, Greengard P, Picciotto MR. Reduction of cocaine place preference in mice lacking the protein phosphatase 1 inhibitors DARPP 32 or Inhibitor 1. Biological Psychiatry. 51: 612-20. PMID 11955461 DOI: 10.1016/S0006-3223(01)01318-X  1
2002 Yamagata Y, Jovanovic JN, Czernik AJ, Greengard P, Obata K. Bidirectional changes in synapsin I phosphorylation at MAP kinase-dependent sites by acute neuronal excitation in vivo. Journal of Neurochemistry. 80: 835-42. PMID 11948247 DOI: 10.1046/j.0022-3042.2001.00753.x  1
2002 Svenningsson P, Tzavara ET, Liu F, Fienberg AA, Nomikos GG, Greengard P. DARPP-32 mediates serotonergic neurotransmission in the forebrain. Proceedings of the National Academy of Sciences of the United States of America. 99: 3188-93. PMID 11880652 DOI: 10.1073/pnas.052712699  1
2002 Svenningsson P, Tzavara ET, Witkin JM, Fienberg AA, Nomikos GG, Greengard P. Involvement of striatal and extrastriatal DARPP-32 in biochemical and behavioral effects of fluoxetine (Prozac). Proceedings of the National Academy of Sciences of the United States of America. 99: 3182-7. PMID 11880651 DOI: 10.1073/pnas.052712799  1
2002 Greenfield JP, Leung LW, Cai D, Kaasik K, Gross RS, Rodriguez-Boulan E, Greengard P, Xu H. Estrogen lowers Alzheimer beta-amyloid generation by stimulating trans-Golgi network vesicle biogenesis. The Journal of Biological Chemistry. 277: 12128-36. PMID 11823458 DOI: 10.1074/jbc.M110009200  1
1997 Cheng XJ, Höög JO, Nairn AC, Greengard P, Aperia A. Regulation of rat Na-K-ATPase activity by PKC is modulated by state of phosphorylation of Ser-943 by PKA. American Journal of Physiology. Cell Physiology. 273: C1981-C1986. PMID 29585085 DOI: 10.1152/ajpcell.1997.273.6.C1981  0.88
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