| Year |
Citation |
Score |
| 2024 |
Powers JM, Leist SR, Mallory ML, Yount BL, Gully KL, Zweigart MR, Bailey AB, Sheahan TP, Harkema JR, Baric RS. Divergent pathogenetic outcomes in BALB/c mice following Omicron subvariant infection. Virus Research. 341: 199319. PMID 38224840 DOI: 10.1016/j.virusres.2024.199319 |
0.513 |
|
| 2023 |
Diefenbacher MV, Baric TJ, Martinez DR, Baric RS, Catanzaro NJ, Sheahan TP. A nano-luciferase expressing human coronavirus OC43 for countermeasure development. Virus Research. 199286. PMID 38016504 DOI: 10.1016/j.virusres.2023.199286 |
0.511 |
|
| 2023 |
Martinez DR, Moreira FR, Zweigart MR, Gully KL, la Cruz G, Brown AJ, Adams LE, Catanzaro N, Yount B, Baric TJ, Mallory ML, Conrad H, May SR, Dong S, Scobey DT, ... ... Sheahan TP, et al. Efficacy of the oral nucleoside prodrug GS-5245 (Obeldesivir) against SARS-CoV-2 and coronaviruses with pandemic potential. Biorxiv : the Preprint Server For Biology. PMID 37425890 DOI: 10.1101/2023.06.27.546784 |
0.609 |
|
| 2023 |
Shoham S, Batista C, Ben Amor Y, Ergonul O, Hassanain M, Hotez P, Kang G, Kim JH, Lall B, Larson HJ, Naniche D, Sheahan T, Strub-Wourgaft N, Sow SO, Wilder-Smith A, et al. Vaccines and therapeutics for immunocompromised patients with COVID-19. Eclinicalmedicine. 59: 101965. PMID 37070102 DOI: 10.1016/j.eclinm.2023.101965 |
0.322 |
|
| 2023 |
Cable J, Sun J, Cheon IS, Vaughan AE, Castro IA, Stein SR, López CB, Gostic KM, Openshaw PJM, Ellebedy AH, Wack A, Hutchinson E, Thomas MM, Langlois RA, Lingwood D, ... ... Sheahan TP, et al. Respiratory viruses: New frontiers-a Keystone Symposia report. Annals of the New York Academy of Sciences. PMID 36722473 DOI: 10.1111/nyas.14958 |
0.36 |
|
| 2022 |
Hagey RJ, Elazar M, Pham EA, Tian S, Ben-Avi L, Bernardin-Souibgui C, Yee MF, Moreira FR, Rabinovitch MV, Meganck RM, Fram B, Beck A, Gibson SA, Lam G, Devera J, ... ... Sheahan TP, et al. Programmable antivirals targeting critical conserved viral RNA secondary structures from influenza A virus and SARS-CoV-2. Nature Medicine. PMID 35982307 DOI: 10.1038/s41591-022-01908-x |
0.341 |
|
| 2022 |
Stevens LJ, Pruijssers AJ, Lee HW, Gordon CJ, Tchesnokov EP, Gribble J, George AS, Hughes TM, Lu X, Li J, Perry JK, Porter DP, Cihlar T, Sheahan TP, Baric RS, et al. Mutations in the SARS-CoV-2 RNA dependent RNA polymerase confer resistance to remdesivir by distinct mechanisms. Science Translational Medicine. eabo0718. PMID 35482820 DOI: 10.1126/scitranslmed.abo0718 |
0.448 |
|
| 2022 |
Yen M, Ren J, Liu Q, Glassman CR, Sheahan TP, Picton LK, Moreira FR, Rustagi A, Jude KM, Zhao X, Blish CA, Baric RS, Su LL, Garcia KC. Facile discovery of surrogate cytokine agonists. Cell. PMID 35325595 DOI: 10.1016/j.cell.2022.02.025 |
0.354 |
|
| 2022 |
Schäfer A, Martinez DR, Won JJ, Meganck RM, Moreira FR, Brown AJ, Gully KL, Zweigart MR, Conrad WS, May SR, Dong S, Kalla R, Chun K, Du Pont V, Babusis D, ... ... Sheahan TP, et al. Therapeutic treatment with an oral prodrug of the remdesivir parental nucleoside is protective against SARS-CoV-2 pathogenesis in mice. Science Translational Medicine. eabm3410. PMID 35315683 DOI: 10.1126/scitranslmed.abm3410 |
0.594 |
|
| 2022 |
Fischer WA, Eron JJ, Holman W, Cohen MS, Fang L, Szewczyk LJ, Sheahan TP, Baric R, Mollan KR, Wolfe CR, Duke ER, Azizad MM, Borroto-Esoda K, Wohl DA, Coombs RW, et al. A phase 2a clinical trial of molnupiravir in patients with COVID-19 shows accelerated SARS-CoV-2 RNA clearance and elimination of infectious virus. Science Translational Medicine. 14: eabl7430. PMID 34941423 DOI: 10.1126/scitranslmed.abl7430 |
0.436 |
|
| 2021 |
Mollan KR, Eron JJ, Krajewski TJ, Painter W, Duke ER, Morse CG, Goecker EA, Premkumar L, Wolfe CR, Szewczyk LJ, Alabanza PL, Loftis AJ, Degli-Angeli EJ, Brown AJ, Dragavon JA, ... ... Sheahan TP, et al. Infectious Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) Virus in Symptomatic Coronavirus Disease 2019 (COVID-19) Outpatients: Host, Disease, and Viral Correlates. Clinical Infectious Diseases : An Official Publication of the Infectious Diseases Society of America. PMID 35022711 DOI: 10.1093/cid/ciab968 |
0.528 |
|
| 2021 |
Walls AC, Miranda MC, Schäfer A, Pham MN, Greaney A, Arunachalam PS, Navarro MJ, Tortorici MA, Rogers K, O'Connor MA, Shirreff L, Ferrell DE, Bowen J, Brunette N, Kepl E, ... ... Sheahan TP, et al. Elicitation of broadly protective sarbecovirus immunity by receptor-binding domain nanoparticle vaccines. Cell. PMID 34619077 DOI: 10.1016/j.cell.2021.09.015 |
0.526 |
|
| 2021 |
Yamin R, Jones AT, Hoffmann HH, Schäfer A, Kao KS, Francis RL, Sheahan TP, Baric RS, Rice CM, Ravetch JV, Bournazos S. Fc-engineered antibody therapeutics with improved anti-SARS-CoV-2 efficacy. Nature. PMID 34547765 DOI: 10.1038/s41586-021-04017-w |
0.486 |
|
| 2021 |
Schäfer A, Martinez DR, Won JJ, Moreira FR, Brown AJ, Gully KL, Kalla R, Chun K, Du Pont V, Babusis D, Tang J, Murakami E, Subramanian R, Barrett KT, Bleier BJ, ... ... Sheahan TP, et al. Therapeutic efficacy of an oral nucleoside analog of remdesivir against SARS-CoV-2 pathogenesis in mice. Biorxiv : the Preprint Server For Biology. PMID 34545367 DOI: 10.1101/2021.09.13.460111 |
0.567 |
|
| 2021 |
Zhang K, Zheludev IN, Hagey RJ, Haslecker R, Hou YJ, Kretsch R, Pintilie GD, Rangan R, Kladwang W, Li S, Wu MT, Pham EA, Bernardin-Souibgui C, Baric RS, Sheahan TP, et al. Cryo-EM and antisense targeting of the 28-kDa frameshift stimulation element from the SARS-CoV-2 RNA genome. Nature Structural & Molecular Biology. PMID 34426697 DOI: 10.1038/s41594-021-00653-y |
0.41 |
|
| 2021 |
Sims AC, Mitchell HD, Gralinski LE, Kyle JE, Burnum-Johnson KE, Lam M, Fulcher ML, West A, Smith RD, Randell SH, Metz TO, Sheahan TP, Waters KM, Baric RS. Unfolded Protein Response Inhibition Reduces Middle East Respiratory Syndrome Coronavirus-Induced Acute Lung Injury. Mbio. e0157221. PMID 34372702 DOI: 10.1128/mBio.01572-21 |
0.516 |
|
| 2021 |
Martinez DR, Schäfer A, Leist SR, Li D, Gully K, Yount B, Feng JY, Bunyan E, Porter DP, Cihlar T, Montgomery SA, Haynes BF, Baric RS, Nussenzweig MC, Sheahan TP. Prevention and therapy of SARS-CoV-2 and the B.1.351 variant in mice. Cell Reports. 109450. PMID 34289384 DOI: 10.1016/j.celrep.2021.109450 |
0.471 |
|
| 2021 |
Fischer W, Eron JJ, Holman W, Cohen MS, Fang L, Szewczyk LJ, Sheahan TP, Baric R, Mollan KR, Wolfe CR, Duke ER, Azizad MM, Borroto-Esoda K, Wohl DA, Loftis AJ, et al. Molnupiravir, an Oral Antiviral Treatment for COVID-19. Medrxiv : the Preprint Server For Health Sciences. PMID 34159342 DOI: 10.1101/2021.06.17.21258639 |
0.455 |
|
| 2021 |
Mollan KR, Eron JJ, Krajewski TJ, Painter W, Duke ER, Morse CG, Goecker EA, Premkumar L, Wolfe CR, Szewczyk LJ, Alabanza PL, Loftis AJ, Degli-Angeli EJ, Brown AJ, Dragavon JA, ... ... Sheahan TP, et al. SARS-CoV-2 infectious virus, viral RNA in nasopharyngeal swabs, and serostatus of symptomatic COVID-19 outpatients in the United States. Medrxiv : the Preprint Server For Health Sciences. PMID 34100024 DOI: 10.1101/2021.05.28.21258011 |
0.487 |
|
| 2021 |
Ravetch J, Yamin R, Jones A, Hoffmann HH, Kao K, Francis R, Sheahan T, Baric R, Rice C, Bournazos S. Fc-engineered antibody therapeutics with improved efficacy against COVID-19. Research Square. PMID 34075373 DOI: 10.21203/rs.3.rs-555612/v1 |
0.489 |
|
| 2021 |
Feng S, Heath E, Jefferson B, Joslyn C, Kvinge H, Mitchell HD, Praggastis B, Eisfeld AJ, Sims AC, Thackray LB, Fan S, Walters KB, Halfmann PJ, Westhoff-Smith D, Tan Q, ... ... Sheahan TP, et al. Hypergraph models of biological networks to identify genes critical to pathogenic viral response. Bmc Bioinformatics. 22: 287. PMID 34051754 DOI: 10.1186/s12859-021-04197-2 |
0.355 |
|
| 2021 |
Zhou S, Hill CS, Sarkar S, Tse LV, Woodburn BMD, Schinazi RF, Sheahan TP, Baric RS, Heise MT, Swanstrom R. β-D-N 4-hydroxycytidine (NHC) Inhibits SARS-CoV-2 Through Lethal Mutagenesis But Is Also Mutagenic To Mammalian Cells. The Journal of Infectious Diseases. PMID 33961695 DOI: 10.1093/infdis/jiab247 |
0.418 |
|
| 2021 |
Zhou S, Hill CS, Clark MU, Sheahan TP, Baric R, Swanstrom R. Primer ID Next-Generation Sequencing for the Analysis of a Broad Spectrum Antiviral Induced Transition Mutations and Errors Rates in a Coronavirus Genome. Bio-Protocol. 11: e3938. PMID 33796612 DOI: 10.21769/BioProtoc.3938 |
0.398 |
|
| 2021 |
Walls AC, Miranda MC, Pham MN, Schäfer A, Greaney A, Arunachalam PS, Navarro MJ, Tortorici MA, Rogers K, O'Connor MA, Shireff L, Ferrell DE, Brunette N, Kepl E, Bowen J, ... ... Sheahan TP, et al. Elicitation of broadly protective sarbecovirus immunity by receptor-binding domain nanoparticle vaccines. Biorxiv : the Preprint Server For Biology. PMID 33758839 DOI: 10.1101/2021.03.15.435528 |
0.539 |
|
| 2021 |
Adams LE, Dinnon KH, Hou YJ, Sheahan TP, Heise MT, Baric RS. Critical ACE2 Determinants of SARS-CoV-2 and Group 2B Coronavirus Infection and Replication. Mbio. 12. PMID 33727353 DOI: 10.1128/mBio.03149-20 |
0.507 |
|
| 2021 |
Martinez DR, Schaefer A, Leist SR, Gully K, Feng JY, Bunyan E, Porter DP, Cihlar T, Montgomery SA, Baric RS, Nussenzweig MC, Sheahan TP. Early therapy with remdesivir and antibody combinations improves COVID-19 disease in mice. Biorxiv : the Preprint Server For Biology. PMID 33532765 DOI: 10.1101/2021.01.27.428478 |
0.466 |
|
| 2021 |
Dinnon KH, Leist SR, Schäfer A, Edwards CE, Martinez DR, Montgomery SA, West A, Yount BL, Hou YJ, Adams LE, Gully KL, Brown AJ, Huang E, Bryant MD, Choong IC, ... ... Sheahan TP, et al. Publisher Correction: A mouse-adapted model of SARS-CoV-2 to test COVID-19 countermeasures. Nature. PMID 33469219 DOI: 10.1038/s41586-020-03107-5 |
0.384 |
|
| 2021 |
Schäfer A, Muecksch F, Lorenzi JCC, Leist SR, Cipolla M, Bournazos S, Schmidt F, Maison RM, Gazumyan A, Martinez DR, Baric RS, Robbiani DF, Hatziioannou T, Ravetch JV, Bieniasz PD, ... ... Sheahan TP, et al. Antibody potency, effector function, and combinations in protection and therapy for SARS-CoV-2 infection in vivo. The Journal of Experimental Medicine. 218. PMID 33211088 DOI: 10.1084/jem.20201993 |
0.527 |
|
| 2020 |
Iserman C, Roden CA, Boerneke MA, Sealfon RSG, McLaughlin GA, Jungreis I, Fritch EJ, Hou YJ, Ekena J, Weidmann CA, Theesfeld CL, Kellis M, Troyanskaya OG, Baric RS, Sheahan TP, et al. Genomic RNA Elements Drive Phase Separation of the SARS-CoV-2 Nucleocapsid. Molecular Cell. PMID 33290746 DOI: 10.1016/j.molcel.2020.11.041 |
0.378 |
|
| 2020 |
Walls AC, Fiala B, Schäfer A, Wrenn S, Pham MN, Murphy M, Tse LV, Shehata L, O'Connor MA, Chen C, Navarro MJ, Miranda MC, Pettie D, Ravichandran R, Kraft JC, ... ... Sheahan TP, et al. Elicitation of Potent Neutralizing Antibody Responses by Designed Protein Nanoparticle Vaccines for SARS-CoV-2. Cell. PMID 33160446 DOI: 10.1016/j.cell.2020.10.043 |
0.494 |
|
| 2020 |
Leist SR, Dinnon KH, Schäfer A, Tse LV, Okuda K, Hou YJ, West A, Edwards CE, Sanders W, Fritch EJ, Gully KL, Scobey T, Brown AJ, Sheahan TP, Moorman NJ, et al. A Mouse-Adapted SARS-CoV-2 Induces Acute Lung Injury and Mortality in Standard Laboratory Mice. Cell. PMID 33031744 DOI: 10.1016/j.cell.2020.09.050 |
0.549 |
|
| 2020 |
Schäfer A, Muecksch F, Lorenzi JCC, Leist SR, Cipolla M, Bournazos S, Schmidt F, Gazumyan A, Baric RS, Robbiani DF, Hatziioannou T, Ravetch JV, Bieniasz PD, Nussenzweig MC, Sheahan TP. Antibody potency, effector function and combinations in protection from SARS-CoV-2 infection . Biorxiv : the Preprint Server For Biology. PMID 32995782 DOI: 10.1101/2020.09.15.298067 |
0.527 |
|
| 2020 |
Dinnon KH, Leist SR, Schäfer A, Edwards CE, Martinez DR, Montgomery SA, West A, Yount BL, Hou YJ, Adams LE, Gully KL, Brown AJ, Huang E, Bryant MD, Choong IC, ... ... Sheahan TP, et al. A mouse-adapted model of SARS-CoV-2 to test COVID-19 countermeasures. Nature. PMID 32854108 DOI: 10.1038/S41586-020-2708-8 |
0.616 |
|
| 2020 |
Walls AC, Fiala B, Schäfer A, Wrenn S, Pham MN, Murphy M, Tse LV, Shehata L, O'Connor MA, Chen C, Navarro MJ, Miranda MC, Pettie D, Ravichandran R, Kraft JC, ... ... Sheahan TP, et al. Elicitation of potent neutralizing antibody responses by designed protein nanoparticle vaccines for SARS-CoV-2. Biorxiv : the Preprint Server For Biology. PMID 32817941 DOI: 10.1101/2020.08.11.247395 |
0.5 |
|
| 2020 |
Zhang K, Zheludev IN, Hagey RJ, Wu MT, Haslecker R, Hou YJ, Kretsch R, Pintilie GD, Rangan R, Kladwang W, Li S, Pham EA, Bernardin-Souibgui C, Baric RS, Sheahan TP, et al. Cryo-electron Microscopy and Exploratory Antisense Targeting of the 28-kDa Frameshift Stimulation Element from the SARS-CoV-2 RNA Genome. Biorxiv : the Preprint Server For Biology. PMID 32743589 DOI: 10.1101/2020.07.18.209270 |
0.44 |
|
| 2020 |
Pruijssers AJ, George AS, Schäfer A, Leist SR, Gralinksi LE, Dinnon KH, Yount BL, Agostini ML, Stevens LJ, Chappell JD, Lu X, Hughes TM, Gully K, Martinez DR, Brown AJ, ... ... Sheahan TP, et al. Remdesivir Inhibits SARS-CoV-2 in Human Lung Cells and Chimeric SARS-CoV Expressing the SARS-CoV-2 RNA Polymerase in Mice. Cell Reports. 107940. PMID 32668216 DOI: 10.1016/J.Celrep.2020.107940 |
0.605 |
|
| 2020 |
Iserman C, Roden C, Boerneke M, Sealfon R, McLaughlin G, Jungreis I, Park C, Boppana A, Fritch E, Hou YJ, Theesfeld C, Troyanskaya OG, Baric RS, Sheahan TP, Weeks K, et al. Specific viral RNA drives the SARS CoV-2 nucleocapsid to phase separate. Biorxiv : the Preprint Server For Biology. PMID 32587965 DOI: 10.1101/2020.06.11.147199 |
0.411 |
|
| 2020 |
Sheahan TP, Frieman MB. The continued epidemic threat of SARS-CoV-2 and implications for the future of global public health. Current Opinion in Virology. 40: 37-40. PMID 32569751 DOI: 10.1016/J.Coviro.2020.05.010 |
0.594 |
|
| 2020 |
Dinnon KH, Leist SR, Schäfer A, Edwards CE, Martinez DR, Montgomery SA, West A, Yount BL, Hou YJ, Adams LE, Gully KL, Brown AJ, Huang E, Bryant MD, Choong IC, ... ... Sheahan TP, et al. A mouse-adapted SARS-CoV-2 model for the evaluation of COVID-19 medical countermeasures. Biorxiv : the Preprint Server For Biology. PMID 32511406 DOI: 10.1101/2020.05.06.081497 |
0.564 |
|
| 2020 |
Pruijssers AJ, George AS, Schäfer A, Leist SR, Gralinksi LE, Dinnon KH, Yount BL, Agostini ML, Stevens LJ, Chappell JD, Lu X, Hughes TM, Gully K, Martinez DR, Brown AJ, ... ... Sheahan TP, et al. Remdesivir potently inhibits SARS-CoV-2 in human lung cells and chimeric SARS-CoV expressing the SARS-CoV-2 RNA polymerase in mice. Biorxiv : the Preprint Server For Biology. PMID 32511392 DOI: 10.1101/2020.04.27.064279 |
0.557 |
|
| 2020 |
Lindesmith LC, Brewer-Jensen PD, Mallory ML, Jensen K, Yount BL, Costantini V, Collins MH, Edwards CE, Sheahan TP, Vinjé J, Baric RS. Virus-host interactions between non-secretors and human norovirus. Cellular and Molecular Gastroenterology and Hepatology. PMID 32289501 DOI: 10.1016/J.Jcmgh.2020.03.006 |
0.591 |
|
| 2020 |
Sheahan TP, Sims AC, Zhou S, Graham RL, Pruijssers AJ, Agostini ML, Leist SR, Schäfer A, Dinnon KH, Stevens LJ, Chappell JD, Lu X, Hughes TM, George AS, Hill CS, et al. An orally bioavailable broad-spectrum antiviral inhibits SARS-CoV-2 in human airway epithelial cell cultures and multiple coronaviruses in mice. Science Translational Medicine. PMID 32253226 DOI: 10.1126/Scitranslmed.Abb5883 |
0.578 |
|
| 2020 |
Sheahan TP, Sims AC, Leist SR, Schäfer A, Won J, Brown AJ, Montgomery SA, Hogg A, Babusis D, Clarke MO, Spahn JE, Bauer L, Sellers S, Porter D, Feng JY, et al. Comparative therapeutic efficacy of remdesivir and combination lopinavir, ritonavir, and interferon beta against MERS-CoV. Nature Communications. 11: 222. PMID 31924756 DOI: 10.1038/S41467-019-13940-6 |
0.577 |
|
| 2019 |
Agostini ML, Pruijssers AJ, Chappell JD, Gribble J, Lu X, Andres EL, Bluemling GR, Lockwood MA, Sheahan TP, Sims AC, Natchus MG, Saindane M, Kolykhalov AA, Painter GR, Baric RS, et al. Small molecule antiviral β-D--hydroxycytidine inhibits a proofreading-intact coronavirus with a high genetic barrier to resistance. Journal of Virology. PMID 31578288 DOI: 10.1128/Jvi.01348-19 |
0.573 |
|
| 2019 |
Leist SR, Jensen KL, Baric RS, Sheahan TP. Increasing the translation of mouse models of MERS coronavirus pathogenesis through kinetic hematological analysis. Plos One. 14: e0220126. PMID 31339932 DOI: 10.1371/Journal.Pone.0220126 |
0.605 |
|
| 2019 |
Brown AJ, Won JJ, Graham RL, Dinnon KH, Sims AC, Feng JY, Cihlar T, Denison MR, Baric RS, Sheahan TP. Broad spectrum antiviral remdesivir inhibits human endemic and zoonotic deltacoronaviruses with a highly divergent RNA dependent RNA polymerase. Antiviral Research. 104541. PMID 31233808 DOI: 10.1016/J.Antiviral.2019.104541 |
0.546 |
|
| 2018 |
Sheahan TP, Baric RS. Is regulation preventing the development of therapeutics that may prevent future coronavirus pandemics? Future Virology. 13: 143-146. PMID 30546388 DOI: 10.2217/Fvl-2017-0143 |
0.46 |
|
| 2018 |
Gralinski LE, Sheahan TP, Morrison TE, Menachery VD, Jensen K, Leist SR, Whitmore A, Heise MT, Baric RS. Complement Activation Contributes to Severe Acute Respiratory Syndrome Coronavirus Pathogenesis. Mbio. 9. PMID 30301856 DOI: 10.1128/Mbio.01753-18 |
0.587 |
|
| 2018 |
Agostini ML, Andres EL, Sims AC, Graham RL, Sheahan TP, Lu X, Smith EC, Case JB, Feng JY, Jordan R, Ray AS, Cihlar T, Siegel D, Mackman RL, Clarke MO, et al. Coronavirus Susceptibility to the Antiviral Remdesivir (GS-5734) Is Mediated by the Viral Polymerase and the Proofreading Exoribonuclease. Mbio. 9. PMID 29511076 DOI: 10.1128/Mbio.00221-18 |
0.582 |
|
| 2018 |
Lindesmith LC, Mallory ML, Debbink K, Donaldson EF, Brewer-Jensen PD, Swann EW, Sheahan TP, Graham RL, Beltramello M, Corti D, Lanzavecchia A, Baric RS. Conformational Occlusion of Blockade Antibody Epitopes, a Novel Mechanism of GII.4 Human Norovirus Immune Evasion. Msphere. 3. PMID 29435493 DOI: 10.1128/mSphere.00518-17 |
0.774 |
|
| 2017 |
Sheahan TP, Sims AC, Graham RL, Menachery VD, Gralinski LE, Case JB, Leist SR, Pyrc K, Feng JY, Trantcheva I, Bannister R, Park Y, Babusis D, Clarke MO, Mackman RL, et al. Broad-spectrum antiviral GS-5734 inhibits both epidemic and zoonotic coronaviruses. Science Translational Medicine. 9. PMID 28659436 DOI: 10.1126/Scitranslmed.Aal3653 |
0.639 |
|
| 2017 |
Jordan R, Hogg A, Warren T, De Wit E, Sheahan T, Lo M, Soloveva V, Weidner J, Gomba L, Feldmann F, Cronin J, Sims A, Cockrell A, Feng J, Trantcheva I, et al. Broad-spectrum Investigational Agent GS-5734 for the Treatment of Ebola, MERS Coronavirus and Other Pathogenic Viral Infections with High Outbreak Potential Open Forum Infectious Diseases. 4: S737-S737. DOI: 10.1093/Ofid/Ofx180.008 |
0.575 |
|
| 2016 |
Ramanan V, Trehan K, Ong ML, Luna JM, Hoffmann HH, Espiritu C, Sheahan TP, Chandrasekar H, Schwartz RE, Christine KS, Rice CM, van Oudenaarden A, Bhatia SN. Viral genome imaging of hepatitis C virus to probe heterogeneous viral infection and responses to antiviral therapies. Virology. 494: 236-247. PMID 27128351 DOI: 10.1016/J.Virol.2016.04.020 |
0.353 |
|
| 2016 |
Menachery VD, Yount BL, Sims AC, Debbink K, Agnihothram SS, Gralinski LE, Graham RL, Scobey T, Plante JA, Royal SR, Swanstrom J, Sheahan TP, Pickles RJ, Corti D, Randell SH, et al. SARS-like WIV1-CoV poised for human emergence. Proceedings of the National Academy of Sciences of the United States of America. PMID 26976607 DOI: 10.1073/Pnas.1517719113 |
0.788 |
|
| 2015 |
Tran V, Poole DS, Jeffery JJ, Sheahan TP, Creech D, Yevtodiyenko A, Peat AJ, Francis KP, You S, Mehle A. Multi-Modal Imaging with a Toolbox of Influenza AReporter Viruses. Viruses. 7: 5319-27. PMID 26473913 DOI: 10.3390/V7102873 |
0.391 |
|
| 2015 |
Wood ER, Bledsoe R, Chai J, Daka P, Deng H, Ding Y, Harris-Gurley S, Kryn LH, Nartey E, Nichols J, Nolte RT, Prabhu N, Rise C, Sheahan T, Shotwell JB, et al. The Role of Phosphodiesterase 12 (PDE12) as a Negative Regulator of the Innate Immune Response and the Discovery of Antiviral Inhibitors. The Journal of Biological Chemistry. PMID 26055709 DOI: 10.1074/Jbc.M115.653113 |
0.353 |
|
| 2014 |
Ramanan V, Scull MA, Sheahan TP, Rice CM, Bhatia SN. New Methods in Tissue Engineering: Improved Models for Viral Infection. Annual Review of Virology. 1: 475-499. PMID 25893203 DOI: 10.1146/Annurev-Virology-031413-085437 |
0.346 |
|
| 2014 |
Sheahan T, Imanaka N, Marukian S, Dorner M, Liu P, Ploss A, Rice CM. Interferon lambda alleles predict innate antiviral immune responses and hepatitis C virus permissiveness. Cell Host & Microbe. 15: 190-202. PMID 24528865 DOI: 10.1016/J.Chom.2014.01.007 |
0.335 |
|
| 2013 |
Schwartz RE, Trehan K, Andrus L, Sheahan T, Ploss A, Duncan SA, Rice CM, Bhatia S. Mo1783 Personalizing the Study of Infectious Disease: Modeling Hepatitis C Virus Using Induced Pluripotent Stem Cells Gastroenterology. 144: S-1025. DOI: 10.1016/S0016-5085(13)63810-X |
0.33 |
|
| 2012 |
Schwartz RE, Trehan K, Andrus L, Sheahan TP, Ploss A, Duncan SA, Rice CM, Bhatia SN. Modeling hepatitis C virus infection using human induced pluripotent stem cells. Proceedings of the National Academy of Sciences of the United States of America. 109: 2544-8. PMID 22308485 DOI: 10.1073/Pnas.1121400109 |
0.395 |
|
| 2012 |
Meuleman P, Teresa Catanese M, Verhoye L, Desombere I, Farhoudi A, Jones CT, Sheahan T, Grzyb K, Cortese R, Rice CM, Leroux-Roels G, Nicosia A. A Human monoclonal antibody targeting scavenger receptor class B type I precludes hepatitis C virus infection and viral spread in vitro and in vivo Hepatology. 55: 364-372. PMID 21953761 DOI: 10.1002/Hep.24692 |
0.393 |
|
| 2012 |
Schwartz R, Trehan K, Andrus L, Sheahan T, Ploss A, Duncan SA, Rice C, Bhatia S. Su1581 Modeling Hepatitis C Virus Infection Using Human Induced Pluripotent Stem Cells Gastroenterology. 142: S-971. DOI: 10.1016/S0016-5085(12)63761-5 |
0.366 |
|
| 2011 |
Andrus L, Marukian S, Jones CT, Catanese MT, Sheahan TP, Schoggins JW, Barry WT, Dustin LB, Trehan K, Ploss A, Bhatia SN, Rice CM. Expression of paramyxovirus V proteins promotes replication and spread of hepatitis C virus in cultures of primary human fetal liver cells. Hepatology (Baltimore, Md.). 54: 1901-12. PMID 22144107 DOI: 10.1002/Hep.24557 |
0.327 |
|
| 2011 |
Sheahan T, Whitmore A, Long K, Ferris M, Rockx B, Funkhouser W, Donaldson E, Gralinski L, Collier M, Heise M, Davis N, Johnston R, Baric RS. Successful vaccination strategies that protect aged mice from lethal challenge from influenza virus and heterologous severe acute respiratory syndrome coronavirus. Journal of Virology. 85: 217-30. PMID 20980507 DOI: 10.1128/Jvi.01805-10 |
0.756 |
|
| 2010 |
Sheahan T, Jones CT, Ploss A. Advances and challenges in studying hepatitis C virus in its native environment. Expert Review of Gastroenterology & Hepatology. 4: 541-50. PMID 20932139 DOI: 10.1586/Egh.10.53 |
0.32 |
|
| 2010 |
Rockx B, Donaldson E, Frieman M, Sheahan T, Corti D, Lanzavecchia A, Baric RS. Escape from human monoclonal antibody neutralization affects in vitro and in vivo fitness of severe acute respiratory syndrome coronavirus. The Journal of Infectious Diseases. 201: 946-55. PMID 20144042 DOI: 10.1086/651022 |
0.78 |
|
| 2010 |
Sheahan TP, Baric RS. SARS coronavirus pathogenesis and therapeutic treatment design Molecular Biology of the Sars-Coronavirus. 195-230. DOI: 10.1007/978-3-642-03683-5_13 |
0.617 |
|
| 2009 |
Rockx B, Baas T, Zornetzer GA, Haagmans B, Sheahan T, Frieman M, Dyer MD, Teal TH, Proll S, van den Brand J, Baric R, Katze MG. Early upregulation of acute respiratory distress syndrome-associated cytokines promotes lethal disease in an aged-mouse model of severe acute respiratory syndrome coronavirus infection. Journal of Virology. 83: 7062-74. PMID 19420084 DOI: 10.1128/Jvi.00127-09 |
0.72 |
|
| 2009 |
Rockx B, Baas T, Zornetzer GA, Haagmans B, Sheahan T, Frieman M, Dyer MD, Teal TH, Proll S, Van Den Brand J, Baric R, Katze MG. Early upregulation of acute respiratory distress syndrome-associated cytokines promotes lethal disease in an aged-mouse model of severe acute respiratory syndrome coronavirus infection (Journal of Virology (2009) 83, 14, (7062-7074)) Journal of Virology. 83: 9022. DOI: 10.1128/Jvi.01322-09 |
0.68 |
|
| 2008 |
Sheahan T, Morrison TE, Funkhouser W, Uematsu S, Akira S, Baric RS, Heise MT. MyD88 is required for protection from lethal infection with a mouse-adapted SARS-CoV. Plos Pathogens. 4: e1000240. PMID 19079579 DOI: 10.1371/Journal.Ppat.1000240 |
0.553 |
|
| 2008 |
Becker MM, Graham RL, Donaldson EF, Rockx B, Sims AC, Sheahan T, Pickles RJ, Corti D, Johnston RE, Baric RS, Denison MR. Synthetic recombinant bat SARS-like coronavirus is infectious in cultured cells and in mice. Proceedings of the National Academy of Sciences of the United States of America. 105: 19944-9. PMID 19036930 DOI: 10.1073/Pnas.0808116105 |
0.734 |
|
| 2008 |
Sheahan T, Rockx B, Donaldson E, Corti D, Baric R. Pathways of cross-species transmission of synthetically reconstructed zoonotic severe acute respiratory syndrome coronavirus. Journal of Virology. 82: 8721-32. PMID 18579604 DOI: 10.1128/Jvi.00818-08 |
0.746 |
|
| 2008 |
Lamirande EW, DeDiego ML, Roberts A, Jackson JP, Alvarez E, Sheahan T, Shieh WJ, Zaki SR, Baric R, Enjuanes L, Subbarao K. A live attenuated severe acute respiratory syndrome coronavirus is immunogenic and efficacious in golden Syrian hamsters. Journal of Virology. 82: 7721-4. PMID 18463152 DOI: 10.1128/Jvi.00304-08 |
0.64 |
|
| 2008 |
Rockx B, Corti D, Donaldson E, Sheahan T, Stadler K, Lanzavecchia A, Baric R. Structural basis for potent cross-neutralizing human monoclonal antibody protection against lethal human and zoonotic severe acute respiratory syndrome coronavirus challenge. Journal of Virology. 82: 3220-35. PMID 18199635 DOI: 10.1128/Jvi.02377-07 |
0.763 |
|
| 2008 |
Roberts A, Lamirande EW, Vogel L, Jackson JP, Paddock CD, Guarner J, Zaki SR, Sheahan T, Baric R, Subbarao K. Animal models and vaccines for SARS-CoV infection. Virus Research. 133: 20-32. PMID 17499378 DOI: 10.1016/J.Virusres.2007.03.025 |
0.614 |
|
| 2008 |
Enjuanes L, Dediego ML, Alvarez E, Deming D, Sheahan T, Baric R. Vaccines to prevent severe acute respiratory syndrome coronavirus-induced disease. Virus Research. 133: 45-62. PMID 17416434 DOI: 10.1016/J.Virusres.2007.01.021 |
0.778 |
|
| 2007 |
Sheahan T, Rockx B, Donaldson E, Sims A, Pickles R, Corti D, Baric R. Mechanisms of zoonotic severe acute respiratory syndrome coronavirus host range expansion in human airway epithelium. Journal of Virology. 82: 2274-85. PMID 18094188 DOI: 10.1128/Jvi.02041-07 |
0.753 |
|
| 2007 |
Zhu Z, Chakraborti S, He Y, Roberts A, Sheahan T, Xiao X, Hensley LE, Prabakaran P, Rockx B, Sidorov IA, Corti D, Vogel L, Feng Y, Kim JO, Wang LF, et al. Potent cross-reactive neutralization of SARS coronavirus isolates by human monoclonal antibodies. Proceedings of the National Academy of Sciences of the United States of America. 104: 12123-8. PMID 17620608 DOI: 10.1073/Pnas.0701000104 |
0.696 |
|
| 2007 |
Rockx B, Sheahan T, Donaldson E, Harkema J, Sims A, Heise M, Pickles R, Cameron M, Kelvin D, Baric R. Synthetic reconstruction of zoonotic and early human severe acute respiratory syndrome coronavirus isolates that produce fatal disease in aged mice. Journal of Virology. 81: 7410-23. PMID 17507479 DOI: 10.1128/Jvi.00505-07 |
0.759 |
|
| 2007 |
Roberts A, Deming D, Paddock CD, Cheng A, Yount B, Vogel L, Herman BD, Sheahan T, Heise M, Genrich GL, Zaki SR, Baric R, Subbarao K. A mouse-adapted SARS-coronavirus causes disease and mortality in BALB/c mice. Plos Pathogens. 3: e5. PMID 17222058 DOI: 10.1371/Journal.Ppat.0030005 |
0.803 |
|
| 2007 |
Deming D, Sheahan T, Heise M, Yount B, Davis N, Sims A, Suthar M, Harkema J, Whitmore A, Pickles R, West A, Donaldson E, Curtis K, Johnston R, Baric R. Correction: Vaccine Efficacy in Senescent Mice Challenged with Recombinant SARS-CoV Bearing Epidemic and Zoonotic Spike Variants Plos Medicine. 4: e80. DOI: 10.1371/Journal.Pmed.0040080 |
0.78 |
|
| 2006 |
Deming D, Sheahan T, Heise M, Yount B, Davis N, Sims A, Suthar M, Harkema J, Whitmore A, Pickles R, West A, Donaldson E, Curtis K, Johnston R, Baric R. Vaccine efficacy in senescent mice challenged with recombinant SARS-CoV bearing epidemic and zoonotic spike variants. Plos Medicine. 3: e525. PMID 17194199 DOI: 10.1371/Journal.Pmed.0030525 |
0.806 |
|
| 2006 |
Baric RS, Sheahan T, Deming D, Donaldson E, Yount B, Sims AC, Roberts RS, Frieman M, Rockx B. SARS coronavirus vaccine development. Advances in Experimental Medicine and Biology. 581: 553-60. PMID 17037597 DOI: 10.1007/978-0-387-33012-9_101 |
0.76 |
|
| 2006 |
Sheahan T, Deming D, Donaldson E, Pickles R, Baric R. Resurrection of an "extinct" SARS-CoV isolate GD03 from late 2003. Advances in Experimental Medicine and Biology. 581: 547-50. PMID 17037596 DOI: 10.1007/978-0-387-33012-9_100 |
0.785 |
|
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