Edward R. LaVallie, Ph.D. - Publications

Affiliations: 
2007 Boston University, Boston, MA, United States 
Area:
Pharmacology, Molecular Biology, Immunology

0/55 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
Low-probability matches (unlikely to be authored by this person)
2023 Rampuria P, Mosyak L, Root AR, Svenson K, Agostino MJ, LaVallie ER. Molecular insights into recognition of GUCY2C by T-cell engaging bispecific antibody anti-GUCY2CxCD3. Scientific Reports. 13: 13408. PMID 37591971 DOI: 10.1038/s41598-023-40467-0  0.01
2021 Fung E, Kang L, Sapashnik D, Benard S, Sievers A, Liu Y, Yan G, Zhou J, Rodriguez L, Ma W, Stochaj WR, LaVallie E, Wroblewska L, Kelleher K, Tam A, et al. Fc-GDF15 glyco-engineering and receptor binding affinity optimization for body weight regulation. Scientific Reports. 11: 8921. PMID 33903632 DOI: 10.1038/s41598-021-87959-5  0.01
2021 Root AR, Guntas G, Katragadda M, Apgar JR, Narula J, Chang CS, Hanscom S, McKenna M, Wade J, Meade C, Ma W, Guo Y, Liu Y, Duan W, Hendershot C, ... ... LaVallie ER, et al. Discovery and optimization of a novel anti-GUCY2c x CD3 bispecific antibody for the treatment of solid tumors. Mabs. 13: 1850395. PMID 33459147 DOI: 10.1080/19420862.2020.1850395  0.01
2020 Mathur D, Root AR, Bugaj-Gaweda B, Bisulco S, Tan X, Fang W, Kearney JC, Lucas J, Guffroy M, Golas J, Rohde CM, Stevens C, Kamperschroer C, Kelleher K, Lawrence-Henderson RF, ... ... LaVallie ER, et al. A Novel GUCY2C-CD3 T cell Engaging Bispecific construct (PF-07062119) for the Treatment of Gastrointestinal Cancers. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. PMID 31996389 DOI: 10.1158/1078-0432.Ccr-19-3275  0.01
2020 Arezes J, Foy NJ, Mchugh K, Quinkert D, Benard S, Sawant A, Frost JN, Armitage AE, Pasricha SR, Lim PJ, Tam MSK, LaVallie ER, Pittman D, Cunningham O, Lambert MA, et al. Antibodies against the erythroferrone N-terminal domain prevent hepcidin suppression and ameliorate murine thalassemia. Blood. PMID 31899794 DOI: 10.1182/blood.2019003140  0.01
2018 Arezes J, Foy N, McHugh K, Sawant A, Quinkert D, Terraube V, Brinth A, Tam M, Lavallie E, Taylor S, Armitage AE, Pasricha SR, Cunningham O, Lambert M, Draper SJ, et al. Erythroferrone inhibits the induction of hepcidin by BMP6. Blood. PMID 30097509 DOI: 10.1182/blood-2018-06-857995  0.01
2016 Root AR, Cao W, Li B, LaPan P, Meade C, Sanford J, Jin M, O'Sullivan C, Cummins E, Lambert M, Sheehan AD, Ma W, Gatto S, Kerns K, Lam K, ... ... LaVallie ER, et al. Development of PF-06671008, a Highly Potent Anti-P-cadherin/Anti-CD3 Bispecific DART Molecule with Extended Half-Life for the Treatment of Cancer. Antibodies (Basel, Switzerland). 5. PMID 31557987 DOI: 10.3390/antib5010006  0.01
2015 Tu C, Terraube V, Sze Pui Tam A, Stochaj W, Fennell BJ, Lin L, Stahl M, LaVallie ER, Somers W, Finlay WJ, Mosyak L, Bard J, Cunningham O. Structural and empirical analyses define side-chain clash repair as the key mediator of stability & affinity improvements in an optimized biotherapeutic scFv. The Journal of Biological Chemistry. PMID 26515064 DOI: 10.1074/jbc.M115.688010  0.01
2015 Kuai J, Mosyak L, Brooks J, Cain M, Carven GJ, Ogawa S, Ishino T, Tam M, Lavallie ER, Yang Z, Ponsel D, Rauchenberger R, Arch R, Pullen N. Characterization of binding mode of action of a blocking anti-platelet-derived growth factor (PDGF)-B monoclonal antibody, MOR8457, reveals conformational flexibility and avidity needed for PDGF-BB to bind PDGF receptor-β. Biochemistry. 54: 1918-29. PMID 25707433 DOI: 10.1021/Bi5015425  0.01
2012 Shih HH, Tu C, Cao W, Klein A, Ramsey R, Fennell BJ, Lambert M, Ní Shúilleabháin D, Autin B, Kouranova E, Laxmanan S, Braithwaite S, Wu L, Ait-Zahra M, Milici AJ, ... ... LaVallie ER, et al. An ultra-specific avian antibody to phosphorylated tau protein reveals a unique mechanism for phosphoepitope recognition. The Journal of Biological Chemistry. 287: 44425-34. PMID 23148212 DOI: 10.1074/jbc.M112.415935  0.01
2011 Goltsman I, Wang X, Lavallie ER, Diblasio-Smith EA, Ovcharenko E, Hoffman A, Abassi Z, Feuerstein GZ, Winaver J. Effects of chronic rosiglitazone treatment on renal handling of salt and water in rats with volume-overload congestive heart failure. Circulation. Heart Failure. 4: 345-54. PMID 21398416 DOI: 10.1161/CIRCHEARTFAILURE.110.960179  0.01
2011 Christaki E, Opal SM, Keith JC, Kessimian N, Palardy JE, Parejo NA, Tan XY, Piche-Nicholas N, Tchistiakova L, Vlasuk GP, Shields KM, Feldman JL, Lavallie ER, Arai M, Mounts W, et al. A monoclonal antibody against RAGE alters gene expression and is protective in experimental models of sepsis and pneumococcal pneumonia. Shock (Augusta, Ga.). 35: 492-8. PMID 21263385 DOI: 10.1097/SHK.0b013e31820b2e1c  0.01
2010 Wang X, Liu X, Zhan Y, Lavallie ER, Diblasio-Smith L, Collins-Racie L, Mounts WM, Rutkowski JL, Xu X, Goltsman I, Abassi Z, Winaver J, Feuerstein GZ. Pharmacogenomic, physiological, and biochemical investigations on safety and efficacy biomarkers associated with the peroxisome proliferator-activated receptor-gamma activator rosiglitazone in rodents: a translational medicine investigation. The Journal of Pharmacology and Experimental Therapeutics. 334: 820-9. PMID 20519551 DOI: 10.1124/jpet.110.167635  0.01
2010 Arai M, Jain S, Weaver AA, Hill AA, Guo Y, Bree AG, Smith MF, Allen SW, LaVallie ER, Young D, Bloom L, Adkins K, O'Toole M. Development and application of a biomarker assay for determining the pharmacodynamic activity of an antagonist candidate biotherapeutic antibody to IL21R in whole blood. Journal of Translational Medicine. 8: 51. PMID 20509950 DOI: 10.1186/1479-5876-8-51  0.01
2010 Guo Y, Hill AA, Ramsey RC, Immermann FW, Corcoran C, Young D, Lavallie ER, Ryan M, Bechard T, Pfeifer R, Warner G, Bologna M, Bloom L, O'Toole M. Assessing agonistic potential of a candidate therapeutic anti-IL21R antibody. Journal of Translational Medicine. 8: 50. PMID 20504348 DOI: 10.1186/1479-5876-8-50  0.01
2010 Christaki E, Opal SM, Keith JC, Kessinian N, Palardy JE, Parejo NA, Lavallie E, Racie L, Mounts W, Malamas MS, Mewshaw RE, Harris HA, Vlasuk GP. Estrogen receptor beta agonism increases survival in experimentally induced sepsis and ameliorates the genomic sepsis signature: a pharmacogenomic study. The Journal of Infectious Diseases. 201: 1250-7. PMID 20205571 DOI: 10.1086/651276  0.01
2010 Li N, Rivéra-Bermúdez MA, Zhang M, Tejada J, Glasson SS, Collins-Racie LA, Lavallie ER, Wang Y, Chang KC, Nagpal S, Morris EA, Flannery CR, Yang Z. LXR modulation blocks prostaglandin E2 production and matrix degradation in cartilage and alleviates pain in a rat osteoarthritis model. Proceedings of the National Academy of Sciences of the United States of America. 107: 3734-9. PMID 20133709 DOI: 10.1073/pnas.0911377107  0.01
2009 Chamberland A, Wang E, Jones AR, Collins-Racie LA, LaVallie ER, Huang Y, Liu L, Morris EA, Flannery CR, Yang Z. Identification of a novel HtrA1-susceptible cleavage site in human aggrecan: evidence for the involvement of HtrA1 in aggrecan proteolysis in vivo. The Journal of Biological Chemistry. 284: 27352-9. PMID 19657146 DOI: 10.1074/jbc.M109.037051  0.01
2009 Lakshman KM, Bhasin S, Corcoran C, Collins-Racie LA, Tchistiakova L, Forlow SB, St Ledger K, Burczynski ME, Dorner AJ, Lavallie ER. Measurement of myostatin concentrations in human serum: Circulating concentrations in young and older men and effects of testosterone administration. Molecular and Cellular Endocrinology. 302: 26-32. PMID 19356623 DOI: 10.1016/J.Mce.2008.12.019  0.01
2009 Quinet EM, Basso MD, Halpern AR, Yates DW, Steffan RJ, Clerin V, Resmini C, Keith JC, Berrodin TJ, Feingold I, Zhong W, Hartman HB, Evans MJ, Gardell SJ, DiBlasio-Smith E, ... ... LaVallie ER, et al. LXR ligand lowers LDL cholesterol in primates, is lipid neutral in hamster, and reduces atherosclerosis in mouse. Journal of Lipid Research. 50: 2358-70. PMID 19318684 DOI: 10.1194/jlr.M900037-JLR200  0.01
2009 Collins-Racie LA, Yang Z, Arai M, Li N, Majumdar MK, Nagpal S, Mounts WM, Dorner AJ, Morris E, LaVallie ER. Global analysis of nuclear receptor expression and dysregulation in human osteoarthritic articular cartilage: reduced LXR signaling contributes to catabolic metabolism typical of osteoarthritis Osteoarthritis and Cartilage / Oars, Osteoarthritis Research Society. 17: 832-842. PMID 19217805  0.01
2009 Collins-Racie LA, Yang Z, Arai M, Li N, Majumdar MK, Nagpal S, Mounts WM, Dorner AJ, Morris E, LaVallie ER. Global analysis of nuclear receptor expression and dysregulation in human osteoarthritic articular cartilage. Reduced LXR signaling contributes to catabolic metabolism typical of osteoarthritis Osteoarthritis and Cartilage. 17: 939-949. DOI: 10.1016/j.joca.2008.12.011  0.01
2008 DiBlasio-Smith EA, Arai M, Quinet EM, Evans MJ, Kornaga T, Basso MD, Chen L, Feingold I, Halpern AR, Liu QY, Nambi P, Savio D, Wang S, Mounts WM, Isler JA, ... ... LaVallie ER, et al. Discovery and implementation of transcriptional biomarkers of synthetic LXR agonists in peripheral blood cells. Journal of Translational Medicine. 6: 59. PMID 18925943 DOI: 10.1186/1479-5876-6-59  0.01
2008 Lavallie ER, Dorner AJ, Burczynski ME. Use of ex vivo systems for biomarker discovery. Current Opinion in Pharmacology. 8: 647-53. PMID 18771752 DOI: 10.1016/j.coph.2008.08.003  0.01
2008 Wagner KR, Fleckenstein JL, Amato AA, Barohn RJ, Bushby K, Escolar DM, Flanigan KM, Pestronk A, Tawil R, Wolfe GI, Eagle M, Florence JM, King WM, Pandya S, Straub V, ... ... Lavallie ER, et al. A phase I/IItrial of MYO-029 in adult subjects with muscular dystrophy. Annals of Neurology. 63: 561-71. PMID 18335515 DOI: 10.1002/ana.21338  0.01
2008 Mosyak L, Georgiadis K, Shane T, Svenson K, Hebert T, McDonagh T, Mackie S, Olland S, Lin L, Zhong X, Kriz R, Reifenberg EL, Collins-Racie LA, Corcoran C, Freeman B, ... ... Lavallie ER, et al. Crystal structures of the two major aggrecan degrading enzymes, ADAMTS4 and ADAMTS5. Protein Science : a Publication of the Protein Society. 17: 16-21. PMID 18042673 DOI: 10.1110/Ps.073287008  0.01
2007 Chockalingam PS, Varadarajan U, Sheldon R, Fortier E, LaVallie ER, Morris EA, Yaworsky PJ, Majumdar MK. Involvement of protein kinase Czeta in interleukin-1beta induction of ADAMTS-4 and type 2 nitric oxide synthase via NF-kappaB signaling in primary human osteoarthritic chondrocytes. Arthritis and Rheumatism. 56: 4074-83. PMID 18050214 DOI: 10.1002/art.23043  0.01
2006 LaVallie ER, Chockalingam PS, Collins-Racie LA, Freeman BA, Keohan CC, Leitges M, Dorner AJ, Morris EA, Majumdar MK, Arai M. Protein kinase Cζ is up-regulated in osteoarthritic cartilage and is required for activation of NF-κB by tumor necrosis factor and interleukin-1 in articular chondrocytes Journal of Biological Chemistry. 281: 24124-24137. PMID 16798739 DOI: 10.1074/jbc.M601905200  0.01
2006 Bridges KG, Chopra R, Lin L, Svenson K, Tam A, Jin G, Cowling R, Lovering F, Akopian TN, DiBlasio-Smith E, Annis-Freeman B, Marvell TH, LaVallie ER, Zollner RS, Bard J, et al. A novel approach to identifying beta-secretase inhibitors: bis-statine peptide mimetics discovered using structure and spot synthesis. Peptides. 27: 1877-85. PMID 16574278 DOI: 10.1016/j.peptides.2006.02.003  0.01
2006 Zeng W, Corcoran C, Collins-Racie LA, Lavallie ER, Morris EA, Flannery CR. Glycosaminoglycan-binding properties and aggrecanase activities of truncated ADAMTSs: comparative analyses with ADAMTS-5, -9, -16 and -18. Biochimica Et Biophysica Acta. 1760: 517-24. PMID 16507336 DOI: 10.1016/j.bbagen.2006.01.013  0.01
2004 Jensen P, Magdaleno S, Lehman KM, Rice DS, Lavallie ER, Collins-Racie L, McCoy JM, Curran T. A neurogenomics approach to gene expression analysis in the developing brain. Brain Research. Molecular Brain Research. 132: 116-27. PMID 15582152 DOI: 10.1016/J.Molbrainres.2004.10.002  0.01
2004 Bromley E, Knapp D, Wardle FC, Sun BI, Collins-Racie L, LaVallie E, Smith JC, Sive HL. Identification and characterisation of the posteriorly-expressed Xenopus neurotrophin receptor homolog genes fullback and fullback-like. Gene Expression Patterns : Gep. 5: 135-40. PMID 15533829 DOI: 10.1016/J.Modgep.2004.05.002  0.01
2004 Collins-Racie LA, Flannery CR, Zeng W, Corcoran C, Annis-Freeman B, Agostino MJ, Arai M, DiBlasio-Smith E, Dorner AJ, Georgiadis KE, Jin M, Tan XY, Morris EA, LaVallie ER. ADAMTS-8 exhibits aggrecanase activity and is expressed in human articular cartilage. Matrix Biology : Journal of the International Society For Matrix Biology. 23: 219-30. PMID 15296936 DOI: 10.1016/j.matbio.2004.05.004  0.01
2004 Arai M, Anderson D, Kurdi Y, Annis-Freeman B, Shields K, Collins-Racie LA, Corcoran C, DiBlasio-Smith E, Pittman DD, Dorner AJ, Morris E, LaVallie ER. Effect of adenovirus-mediated overexpression of bovine ADAMTS-4 and human ADAMTS-5 in primary bovine articular chondrocyte pellet culture system. Osteoarthritis and Cartilage / Oars, Osteoarthritis Research Society. 12: 599-613. PMID 15262240 DOI: 10.1016/j.joca.2004.05.001  0.01
2003 Lu Z, LaVallie ER, McCoy JM. Using bio-panning of FLITRX peptide libraries displayed on E. coli cell surface to study protein-protein interactions. Methods in Molecular Biology (Clifton, N.J.). 205: 267-80. PMID 12491893  0.01
2003 LaVallie ER, DiBlasio-Smith EA, Collins-Racie LA, Lu Z, McCoy JM. Thioredoxin and related proteins as multifunctional fusion tags for soluble expression in E. coli. Methods in Molecular Biology (Clifton, N.J.). 205: 119-40. PMID 12491883  0.01
2003 Horsfield J, Ramachandran A, Reuter K, LaVallie E, Collins-Racie L, Crosier K, Crosier P. Cadherin-17 is required to maintain pronephric duct integrity during zebrafish development. Mechanisms of Development. 115: 15-26. PMID 12049763 DOI: 10.1016/s0925-4773(02)00094-1  0.01
2002 Flannery CR, Zeng W, Corcoran C, Collins-Racie LA, Chockalingam PS, Hebert T, Mackie SA, McDonagh T, Crawford TK, Tomkinson KN, LaVallie ER, Morris EA. Autocatalytic cleavage of ADAMTS-4 (Aggrecanase-1) reveals multiple glycosaminoglycan-binding sites. The Journal of Biological Chemistry. 277: 42775-80. PMID 12202483 DOI: 10.1074/jbc.M205309200  0.01
2002 Westling J, Fosang AJ, Last K, Thompson VP, Tomkinson KN, Hebert T, McDonagh T, Collins-Racie LA, LaVallie ER, Morris EA, Sandy JD. ADAMTS4 cleaves at the aggrecanase site (Glu373-Ala374) and secondarily at the matrix metalloproteinase site (Asn341-Phe342) in the aggrecan interglobular domain. The Journal of Biological Chemistry. 277: 16059-66. PMID 11854269 DOI: 10.1074/jbc.M108607200  0.01
2001 LaVallie ER. Production of recombinant proteins in Escherichia coli Current Protocols in Protein Science / Editorial Board, John E. Coligan ... [Et Al.]. PMID 18429175  0.01
2001 LaVallie ER, McCoy JM, Smith DB, Riggs P. Enzymatic and chemical cleavage of fusion proteins Current Protocols in Molecular Biology / Edited by Frederick M. Ausubel ... [Et Al.]. PMID 18265131  0.01
2001 Crosier PS, Bardsley A, Horsfield JA, Krassowska AK, Lavallie ER, Collins-Racie LA, Postlethwait JH, Yan YL, Mccoy JM, Crosier KE. In situ hybridization screen in zebrafish for the selection of genes encoding secreted proteins Developmental Dynamics. 222: 637-644. PMID 11748832 DOI: 10.1002/dvdy.1218  0.01
2001 Smith DM, Collins-Racie LA, Marigo VA, Roberts DJ, Davis NM, Hartmann C, Schweitzer R, LaVallie ER, Gamer L, McCoy J, Tabin CJ. Cloning and expression of a novel cysteine-rich secreted protein family member expressed in thyroid and pancreatic mesoderm within the chicken embryo. Mechanisms of Development. 102: 223-6. PMID 11287197 DOI: 10.1016/S0925-4773(01)00293-3  0.01
2000 Lavallie ER, Lu Z, Diblasio-Smith EA, Collins-Racie LA, Mccoy JM. Thioredoxin as a fusion partner for production of soluble recombinant proteins in Escherichia coli Methods in Enzymology. 326: 322-340. PMID 11036651  0.01
1999 Sun BI, Bush SM, Collins-Racie LA, LaVallie ER, DiBlasio-Smith EA, Wolfman NM, McCoy JM, Sive HL. derrière: a TGF-beta family member required for posterior development in Xenopus. Development (Cambridge, England). 126: 1467-82. PMID 10068640  0.01
1998 Smith PA, Tripp BC, DiBlasio-Smith EA, Lu Z, LaVallie ER, McCoy JM. A plasmid expression system for quantitative in vivo biotinylation of thioredoxin fusion proteins in Escherichia coli Nucleic Acids Research. 26: 1414-1420. PMID 9490786 DOI: 10.1093/Nar/26.6.1414  0.01
1996 Vozza LA, Wittwer L, Higgins DR, Purcell TJ, Bergseid M, Collins-Racie LA, LaVallie ER, Hoeffler JP. Production of a recombinant bovine enterokinase catalytic subunit in the methylotrophic yeast Pichia pastoris. Bio/Technology (Nature Publishing Company). 14: 77-81. PMID 9636316  0.01
1996 Lu Z, DiBlasio-Smith EA, Grant KL, Warne NW, LaVallie ER, Collins-Racie LA, Follettie MT, Williamson MJ, McCoy JM. Histidine patch thioredoxins. Mutant forms of thioredoxin with metal chelating affinity that provide for convenient purifications of thioredoxin fusion proteins. The Journal of Biological Chemistry. 271: 5059-65. PMID 8617783  0.01
1995 Collins-Racie LA, McColgan JM, Grant KL, Diblasio-Smith EA, McCoy JM, Lavallie ER. Production of recombinant bovine enterokinase catalytic subunit in Escherichia coli using the novel secretory fusion partner dsba Bio/Technology. 13: 982-987. PMID 9636275 DOI: 10.1038/nbt0995-982  0.01
1995 Lu Z, Murray KS, Van Cleave V, Lavallie ER, Stahl ML, McCoy JM. Expression of thioredoxin random peptide libraries on the escherichia coli cell surfeice as functional fusions to flagellin: A system designed for exploring protein-protein interactions Bio/Technology. 13: 366-372. PMID 9634778 DOI: 10.1038/nbt0495-366  0.01
1995 LaVallie ER, McCoy JM. Gene fusion expression systems in Escherichia coli Current Opinion in Biotechnology. 6: 501-506. PMID 7579661 DOI: 10.1016/0958-1669(95)80083-2  0.01
1993 LaVallie ER, Rehemtulla A, Racie LA, DiBlasio EA, Ferenz C, Grant KL, Light A, McCoy JM. Cloning and functional expression of a cDNA encoding the catalytic subunit of bovine enterokinase Journal of Biological Chemistry. 268: 23311-23317. PMID 8226855  0.01
1993 LaVallie ER, DiBlasio EA, Kovacic S, Grant KL, Schendel PF, McCoy JM. An e. coli expression system that allows high-level soluble production of heterologous proteins Protein Engineering, Design and Selection. 6: 30. DOI: 10.1093/protein/6.Supplement.30-a  0.01
1993 LaVallie ER, DiBlasio EA, Kovacic S, Grant KL, Schendel PF, McCoy JM. A thioredoxin gene fusion expression system that circumvents inclusion body formation in the E. coli cytoplasm Nature Biotechnology. 11: 187-193. DOI: 10.1038/nbt0293-187  0.01
1989 LaVallie ER, Stahl ML. Cloning of the flagellin gene from Bacillus subtilis and complementation studies of an in vitro-derived deletion mutation Journal of Bacteriology. 171: 3085-3094. PMID 2498283 DOI: 10.1128/JB.171.6.3085-3094.1989  0.01
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