Karthik Rajasekaran - Publications

Affiliations: 
University of Virginia, Charlottesville, VA 
Area:
Seizures, epilepsy, GABA, AMPA

21 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2022 Rana RR, Rajasekaran K, Knappertz V, Gray RA. Pharmacodynamic synergism contributes to the antiseizure action of cannabidiol and clobazam. Experimental Neurology. 114286. PMID 36442674 DOI: 10.1016/j.expneurol.2022.114286  0.309
2019 Jakkamsetti V, Marin-Valencia I, Ma Q, Good LB, Terrill T, Rajasekaran K, Pichumani K, Khemtong C, Hooshyar MA, Sundarrajan C, Patel MS, Bachoo RM, Malloy CR, Pascual JM. Brain metabolism modulates neuronal excitability in a mouse model of pyruvate dehydrogenase deficiency. Science Translational Medicine. 11. PMID 30787166 DOI: 10.1126/Scitranslmed.Aan0457  0.364
2018 Joshi S, Rajasekaran K, Hawk KM, Chester SJ, Goodkin HP. Status Epilepticus: Role for etiology in determining response to benzodiazepines. Annals of Neurology. PMID 29572918 DOI: 10.1002/Ana.25213  0.549
2017 Joshi S, Sun H, Rajasekaran K, Williamson J, Perez-Reyes E, Kapur J. A novel therapeutic approach for treatment of catamenial epilepsy. Neurobiology of Disease. 111: 127-137. PMID 29274741 DOI: 10.1016/J.Nbd.2017.12.009  0.708
2017 Joshi S, Rajasekaran K, Williamson J, Kapur J. Neurosteroid-sensitive δ-GABAA receptors: A role in epileptogenesis? Epilepsia. 58: 494-504. PMID 28452419 DOI: 10.1111/Epi.13660  0.65
2017 Joshi S, Rajasekaran K, Sun H, Williamson J, Kapur J. Enhanced AMPA receptor-mediated neurotransmission on CA1 pyramidal neurons during status epilepticus. Neurobiology of Disease. PMID 28377128 DOI: 10.1016/J.Nbd.2017.03.017  0.699
2015 Zanelli SA, Rajasekaran K, Grosenbaugh DK, Kapur J. Increased excitability and excitatory synaptic transmission during in vitro ischemia in the neonatal mouse hippocampus. Neuroscience. 310: 279-89. PMID 26404876 DOI: 10.1016/j.neuroscience.2015.09.046  0.501
2015 Joshi S, Rajasekaran K, Hawk KM, Brar J, Ross BM, Tran CA, Chester SJ, Goodkin HP. Phosphatase inhibition prevents the activity-dependent trafficking of GABAA receptors during status epilepticus in the young animal. Epilepsia. 56: 1355-65. PMID 26248944 DOI: 10.1111/Epi.13098  0.601
2013 Rajasekaran K, Joshi S, Kozhemyakin M, Todorovic MS, Kowalski S, Balint C, Kapur J. Receptor trafficking hypothesis revisited: plasticity of AMPA receptors during established status epilepticus. Epilepsia. 54: 14-6. PMID 24001062 DOI: 10.1111/Epi.12266  0.683
2013 Kozhemyakin M, Rajasekaran K, Todorovic MS, Kowalski SL, Balint C, Kapur J. Somatostatin type-2 receptor activation inhibits glutamate release and prevents status epilepticus. Neurobiology of Disease. 54: 94-104. PMID 23473742 DOI: 10.1016/J.Nbd.2013.02.015  0.653
2013 Joshi S, Rajasekaran K, Kapur J. GABAergic transmission in temporal lobe epilepsy: the role of neurosteroids. Experimental Neurology. 244: 36-42. PMID 22101060 DOI: 10.1016/J.Expneurol.2011.10.028  0.675
2012 Rajasekaran K, Todorovic M, Kapur J. Calcium-permeable AMPA receptors are expressed in a rodent model of status epilepticus. Annals of Neurology. 72: 91-102. PMID 22829271 DOI: 10.1002/Ana.23570  0.625
2011 Rajasekaran K, Goodkin HP. A swell in the armamentarium of antiepileptic drug targets. Epilepsy Currents / American Epilepsy Society. 11: 172-6. PMID 22131899 DOI: 10.5698/1535-7511-11.6.172  0.331
2010 Rajasekaran K, Zanelli SA, Goodkin HP. Lessons from the laboratory: the pathophysiology, and consequences of status epilepticus. Seminars in Pediatric Neurology. 17: 136-43. PMID 20727481 DOI: 10.1016/J.Spen.2010.06.002  0.429
2010 Rajasekaran K, Joshi S, Sun C, Mtchedlishvilli Z, Kapur J. Receptors with low affinity for neurosteroids and GABA contribute to tonic inhibition of granule cells in epileptic animals. Neurobiology of Disease. 40: 490-501. PMID 20682339 DOI: 10.1016/J.Nbd.2010.07.016  0.692
2010 Kozhemyakin M, Rajasekaran K, Kapur J. Central cholinesterase inhibition enhances glutamatergic synaptic transmission. Journal of Neurophysiology. 103: 1748-57. PMID 20107127 DOI: 10.1152/Jn.00949.2009  0.608
2009 Rajasekaran K, Sun C, Bertram EH. Altered pharmacology and GABA-A receptor subunit expression in dorsal midline thalamic neurons in limbic epilepsy. Neurobiology of Disease. 33: 119-32. PMID 18992345 DOI: 10.1016/J.Nbd.2008.09.023  0.48
2007 Rajasekaran K, Kapur J, Bertram EH. Alterations in GABA(A) receptor mediated inhibition in adjacent dorsal midline thalamic nuclei in a rat model of chronic limbic epilepsy. Journal of Neurophysiology. 98: 2501-8. PMID 17855591 DOI: 10.1152/Jn.00139.2007  0.64
2005 Rajasekaran K. Seizure-induced oxidative stress in rat brain regions: blockade by nNOS inhibition. Pharmacology, Biochemistry, and Behavior. 80: 263-72. PMID 15680179 DOI: 10.1016/J.Pbb.2004.11.007  0.421
2003 Rajasekaran K, Jayakumar R, Venkatachalam K. Increased neuronal nitric oxide synthase (nNOS) activity triggers picrotoxin-induced seizures in rats and evidence for participation of nNOS mechanism in the action of antiepileptic drugs. Brain Research. 979: 85-97. PMID 12850575 DOI: 10.1016/S0006-8993(03)02878-6  0.477
2001 Paul V, Subramanian EH, Rajasekaran K. Pharmacological evidence for a role of gamma-aminobutyric acid A receptor mechanism in modulating nitric oxide synthase activity in rat brain. Neurochemistry International. 38: 209-11. PMID 11099778 DOI: 10.1016/S0197-0186(00)00081-4  0.403
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