Simon Lovestone, PhD, MRCPsych - Related publications

Old Age Psychiatry King's College London, London, UK 
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50 most relevant papers in past 60 days:
Year Citation  Score
2019 Oliver DMA, Reddy PH. Molecular Basis of Alzheimer's Disease: Focus on Mitochondria. Journal of Alzheimer's Disease : Jad. PMID 30932888 DOI: 10.3233/JAD-190048   
2019 Ottoy J, Niemantsverdriet E, Verhaeghe J, De Roeck E, Struyfs H, Somers C, Wyffels L, Ceyssens S, Van Mossevelde S, Van den Bossche T, Van Broeckhoven C, Ribbens A, Bjerke M, Stroobants S, Engelborghs S, et al. Association of short-term cognitive decline and MCI-to-AD dementia conversion with CSF, MRI, amyloid- and F-FDG-PET imaging. Neuroimage. Clinical. 22: 101771. PMID 30927601 DOI: 10.1016/j.nicl.2019.101771   
2019 Cho H, Choi JY, Lee HS, Lee JH, Ryu YH, Lee MS, Jack CR, Lyoo CH. Progressive tau accumulation in Alzheimer's disease: two-year follow-up study. Journal of Nuclear Medicine : Official Publication, Society of Nuclear Medicine. PMID 30926651 DOI: 10.2967/jnumed.118.221697   
2019 Dourlen P, Kilinc D, Malmanche N, Chapuis J, Lambert JC. The new genetic landscape of Alzheimer's disease: from amyloid cascade to genetically driven synaptic failure hypothesis? Acta Neuropathologica. PMID 30982098 DOI: 10.1007/s00401-019-02004-0   
2019 Quitterer U, AbdAlla S. Improvements of Symptoms of Alzheimer`s Disease by Inhibition of the Angiotensin System. Pharmacological Research. PMID 30991105 DOI: 10.1016/j.phrs.2019.04.014   
2019 Ma G, Liu M, Du K, Zhong X, Gong S, Jiao L, Wei M. Differential Expression of mRNAs in the Brain Tissues of Patients with Alzheimer's Disease Based on GEO Expression Profile and Its Clinical Significance. Biomed Research International. 2019: 8179145. PMID 30918899 DOI: 10.1155/2019/8179145   
2019 Li K, Luo X, Zeng Q, Huang P, Shen Z, Xu X, Xu J, Wang C, Zhou J, Zhang M, . Gray matter structural covariance networks changes along the Alzheimer's disease continuum. Neuroimage. Clinical. 23: 101828. PMID 31029051 DOI: 10.1016/j.nicl.2019.101828   
2019 Sergeant N, Vingtdeux V, Eddarkaoui S, Gay M, Evrard C, Le Fur N, Laurent C, Caillierez R, Obriot H, Larchanché PE, Farce A, Coevoet M, Carato P, Kouach M, Descat A, et al. New piperazine multi-effect drugs prevent neurofibrillary degeneration and amyloid deposition, and preserve memory in animal models of Alzheimer's disease. Neurobiology of Disease. PMID 30928644 DOI: 10.1016/j.nbd.2019.03.028   
2019 Deshpande P, Gogia N, Singh A. Exploring the efficacy of natural products in alleviating Alzheimer's disease. Neural Regeneration Research. 14: 1321-1329. PMID 30964049 DOI: 10.4103/1673-5374.253509   
2019 Leonenko G, Sims R, Shoai M, Frizzati A, Bossù P, Spalletta G, Fox NC, Williams J, , Hardy J, Escott-Price V. Polygenic risk and hazard scores for Alzheimer's disease prediction. Annals of Clinical and Translational Neurology. 6: 456-465. PMID 30911569 DOI: 10.1002/acn3.716   
2019 Cho SJ, Lim HJ, Jo C, Park MH, Han C, Koh YH. Plasma ATG5 is increased in Alzheimer's disease. Scientific Reports. 9: 4741. PMID 30894637 DOI: 10.1038/s41598-019-41347-2   
2019 Giau VV, Senanarong V, Bagyinszky E, An SSA, Kim S. Analysis of 50 Neurodegenerative Genes in Clinically Diagnosed Early-Onset Alzheimer's Disease. International Journal of Molecular Sciences. 20. PMID 30917570 DOI: 10.3390/ijms20061514   
2019 Deng L, Wang Y. [Progress in the study of the imaging genomics of Alzheimer's disease]. Sheng Wu Yi Xue Gong Cheng Xue Za Zhi = Journal of Biomedical Engineering = Shengwu Yixue Gongchengxue Zazhi. 36: 140-145. PMID 30887788 DOI: 10.7507/1001-5515.201805061   
2019 Nudelman KNH, McDonald BC, Lahiri DK, Saykin AJ. Biological Hallmarks of Cancer in Alzheimer's Disease. Molecular Neurobiology. PMID 30993533 DOI: 10.1007/s12035-019-1591-5   
2019 Power R, Prado-Cabrero A, Mulcahy R, Howard A, Nolan JM. The Role of Nutrition for the Aging Population: Implications for Cognition and Alzheimer's Disease. Annual Review of Food Science and Technology. 10: 619-639. PMID 30908950 DOI: 10.1146/annurev-food-030216-030125   
2019 Wang F, Chen D, Wu P, Klein C, Jin C. Formaldehyde, Epigenetics and Alzheimer's disease. Chemical Research in Toxicology. PMID 30964647 DOI: 10.1021/acs.chemrestox.9b00090   
2019 Pontecorvo MJ, Devous MD, Kennedy I, Navitsky M, Lu M, Galante N, Salloway S, Doraiswamy PM, Southekal S, Arora AK, McGeehan A, Lim NC, Xiong H, Truocchio SP, Joshi AD, et al. A multicentre longitudinal study of flortaucipir (18F) in normal ageing, mild cognitive impairment and Alzheimer's disease dementia. Brain : a Journal of Neurology. PMID 31009046 DOI: 10.1093/brain/awz090   
2019 Sharma HS, Muresanu DF, Castellani RJ, Nozari A, Lafuente JV, Tian ZR, Ozkizilcik A, Manzhulo I, Mössler H, Sharma A. Nanowired delivery of cerebrolysin with neprilysin and p-Tau antibodies induces superior neuroprotection in Alzheimer's disease. Progress in Brain Research. 245: 145-200. PMID 30961867 DOI: 10.1016/bs.pbr.2019.03.009   
2019 Zetterberg H, Burnham SC. Blood-based molecular biomarkers for Alzheimer's disease. Molecular Brain. 12: 26. PMID 30922367 DOI: 10.1186/s13041-019-0448-1   
2019 Park JE, Choi KY, Kim BC, Choi SM, Song MK, Lee JJ, Kim J, Song HC, Kim HW, Ha JM, Seo EH, Song WK, Park SG, Lee JS, Lee KH. Cerebrospinal Fluid Biomarkers for the Diagnosis of Prodromal Alzheimer's Disease in Amnestic Mild Cognitive Impairment. Dementia and Geriatric Cognitive Disorders Extra. 9: 100-113. PMID 31011328 DOI: 10.1159/000496920   
2019 Yan T, Wang Y, Weng Z, Du W, Liu T, Chen D, Li X, Wu J, Han Y. Early-Stage Identification and Pathological Development of Alzheimer's Disease Using Multimodal MRI. Journal of Alzheimer's Disease : Jad. PMID 30958352 DOI: 10.3233/JAD-181049   
2019 Startin CM, Ashton NJ, Hamburg S, Hithersay R, Wiseman FK, Mok KY, Hardy J, Lleó A, Lovestone S, Parnetti L, Zetterberg H, Hye A, , Strydom A. Plasma biomarkers for amyloid, tau, and cytokines in Down syndrome and sporadic Alzheimer's disease. Alzheimer's Research & Therapy. 11: 26. PMID 30902060 DOI: 10.1186/s13195-019-0477-0   
2019 Lin CN, Huang CC, Huang KL, Lin KJ, Yen TC, Kuo HC. A metabolomic approach to identifying biomarkers in blood of Alzheimer's disease. Annals of Clinical and Translational Neurology. 6: 537-545. PMID 30911577 DOI: 10.1002/acn3.726   
2019 Kang SW, Jeon S, Yoo HS, Chung SJ, Lee PH, Sohn YH, Yun M, Evans AC, Ye BS. Effects of Lewy body disease and Alzheimer disease on brain atrophy and cognitive dysfunction. Neurology. PMID 30944239 DOI: 10.1212/WNL.0000000000007373   
2019 Qin Q, Li Y. Herpesviral infections and antimicrobial protection for Alzheimer's disease: Implications for prevention and treatment. Journal of Medical Virology. PMID 30997676 DOI: 10.1002/jmv.25481   
2019 Grobe W, Bieber T, Novak N. Pathophysiology of atopic dermatitis. Journal Der Deutschen Dermatologischen Gesellschaft = Journal of the German Society of Dermatology : Jddg. 17: 433-440. PMID 30958934 DOI: 10.1111/ddg.13819   
2019 Guo H, Zhao Z, Zhang R, Chen P, Zhang X, Cheng F, Gou X. Monocytes in the Peripheral Clearance of Amyloid-β and Alzheimer's Disease. Journal of Alzheimer's Disease : Jad. PMID 30958361 DOI: 10.3233/JAD-181177   
2019 Forlenza OV, Radanovic M, Talib LL, Gattaz WF. Clinical and biological effects of long-term lithium treatment in older adults with amnestic mild cognitive impairment: randomised clinical trial. The British Journal of Psychiatry : the Journal of Mental Science. 1-7. PMID 30947755 DOI: 10.1192/bjp.2019.76   
2019 Hansen D, Ling H, Lashley T, Holton JL, Warner TT. Clinical, neuropathological and genetic features of Lewy body dementias. Neuropathology and Applied Neurobiology. PMID 30977926 DOI: 10.1111/nan.12554   
2019 Wright SM, Jensen SL, Cockriel KL, Davis B, Tschanz JT, Munger RG, Corcoran CD, Kauwe JSK. Association study of rs3846662 with Alzheimer's disease in a population-based cohort: the Cache County Study. Neurobiology of Aging. PMID 30975575 DOI: 10.1016/j.neurobiolaging.2019.03.004   
2019 Goudey B, Fung BJ, Schieber C, Faux NG, , . A blood-based signature of cerebrospinal fluid Aβ status. Scientific Reports. 9: 4163. PMID 30853713 DOI: 10.1038/s41598-018-37149-7   
2019 El Hajj H, Savage JC, Bisht K, Parent M, Vallières L, Rivest S, Tremblay MÈ. Ultrastructural evidence of microglial heterogeneity in Alzheimer's disease amyloid pathology. Journal of Neuroinflammation. 16: 87. PMID 30992040 DOI: 10.1186/s12974-019-1473-9   
2019 Li KX, Sun Q, Wei LL, Du GH, Huang X, Wang JK. ERα Gene Promoter Methylation in Cognitive Function and Quality of Life of Patients With Alzheimer Disease. Journal of Geriatric Psychiatry and Neurology. 891988719835325. PMID 30947592 DOI: 10.1177/0891988719835325   
2019 Wang W, Li J, Zhang H, Wang X, Zhang X. Effects of vitamin E supplementation on the risk and progression of AD: a systematic review and meta-analysis. Nutritional Neuroscience. 1-10. PMID 30900960 DOI: 10.1080/1028415X.2019.1585506   
2019 Fitz NF, Nam KN, Koldamova R, Lefterov I. Therapeutic Targeting of Nuclear Receptors, LXR and RXR, for Alzheimer's Disease. British Journal of Pharmacology. PMID 30924124 DOI: 10.1111/bph.14668   
2019 Rosas-Hernandez H, Cuevas E, Raymick JB, Robinson BL, Ali SF, Hanig J, Sarkar S. Characterization of Serum Exosomes from a Transgenic Mouse Model of Alzheimer's Disease. Current Alzheimer Research. PMID 30907317 DOI: 10.2174/1567205016666190321155422   
2019 Fang EF. Mitophagy and NAD inhibit Alzheimer disease. Autophagy. 1-3. PMID 30922179 DOI: 10.1080/15548627.2019.1596497   
2019 Vergallo A, Giampietri L, Pagni C, Giorgi FS, Nicoletti V, Miccoli M, Libertini P, Petrozzi L, Bonuccelli U, Tognoni G. Association Between CSF Beta-Amyloid and Apathy in Early-Stage Alzheimer Disease. Journal of Geriatric Psychiatry and Neurology. 32: 164-169. PMID 30913958 DOI: 10.1177/0891988719838627   
2019 Matta SA, Blanchet-Rethore S, Sio YY, Suri BK, Andiappan AK, Anantharaman R, Piketty C, Bourdes V, Chew FT. Different phenotypes and factors associated with atopic dermatitis in the young adult Singaporean Chinese population: A cross-sectional study. The World Allergy Organization Journal. 12: 100008. PMID 30937133 DOI: 10.1016/j.waojou.2018.11.006   
2019 Patel H, Dobson RJB, Newhouse SJ. A Meta-Analysis of Alzheimer's Disease Brain Transcriptomic Data. Journal of Alzheimer's Disease : Jad. PMID 30909231 DOI: 10.3233/JAD-181085   
2019 Lyra E Silva NM, Gonçalves RA, Boehnke SE, Forny-Germano L, Munoz DP, De Felice FG. Understanding the link between insulin resistance and Alzheimer's disease: Insights from animal models. Experimental Neurology. PMID 30930096 DOI: 10.1016/j.expneurol.2019.03.016   
2019 Mazumder MK, Choudhury S. Tea polyphenols as multi-target therapeutics for Alzheimer's disease: An in silico study. Medical Hypotheses. 125: 94-99. PMID 30902161 DOI: 10.1016/j.mehy.2019.02.035   
2019 Ruthirakuhan M, Herrmann N, Vieira D, Gallagher D, Lanctôt KL. The Roles of Apathy and Depression in Predicting Alzheimer Disease: A Longitudinal Analysis in Older Adults With Mild Cognitive Impairment. The American Journal of Geriatric Psychiatry : Official Journal of the American Association For Geriatric Psychiatry. PMID 30910421 DOI: 10.1016/j.jagp.2019.02.003   
2019 McFall GP, Bӓckman L, Dixon RA. Nuances in Alzheimer's Genetic Risk Reveal Differential Predictions of Non-demented Memory Aging Trajectories: Selective Patterns by APOE Genotype and Sex. Current Alzheimer Research. PMID 30873923 DOI: 10.2174/1567205016666190315094452   
2019 Li WW, Shen YY, Tian DY, Bu XL, Zeng F, Liu YH, Chen Y, Yao XQ, Li HY, Chen DW, Zhou FY, Yang H, Li QM, Bao WQ, Guan YH, et al. Brain Amyloid-β Deposition and Blood Biomarkers in Patients with Clinically Diagnosed Alzheimer's Disease. Journal of Alzheimer's Disease : Jad. PMID 30958377 DOI: 10.3233/JAD-190056   
2019 Gao G, He J, Luo Y, Sun Y, Zhou Y, Zhang J, Xing Y, Dai J. Axonopathy likely initiates neuropathological processes via a mechanism of axonal leakage in Alzheimer's mouse models. Current Molecular Medicine. PMID 30961496 DOI: 10.2174/1566524019666190405174908   
2019 Iadecola C, Gottesman RF. Neurovascular and Cognitive Dysfunction in Hypertension. Circulation Research. 124: 1025-1044. PMID 30920929 DOI: 10.1161/CIRCRESAHA.118.313260   
2019 Bransby L, Lim YY, Ames D, Fowler C, Roberston J, Harrington K, Snyder PJ, Villemagne VL, Salvado O, Masters CL, Maruff P. Sensitivity of a Preclinical Alzheimer's Cognitive Composite (PACC) to amyloid β load in preclinical Alzheimer's disease. Journal of Clinical and Experimental Neuropsychology. 1-10. PMID 30924399 DOI: 10.1080/13803395.2019.1593949   
2019 Egan MF, Kost J, Voss T, Mukai Y, Aisen PS, Cummings JL, Tariot PN, Vellas B, van Dyck CH, Boada M, Zhang Y, Li W, Furtek C, Mahoney E, Harper Mozley L, et al. Randomized Trial of Verubecestat for Prodromal Alzheimer's Disease. The New England Journal of Medicine. 380: 1408-1420. PMID 30970186 DOI: 10.1056/NEJMoa1812840   
2019 Walker L, McAleese KE, Erskine D, Attems J. Neurodegenerative Diseases and Ageing. Sub-Cellular Biochemistry. 91: 75-106. PMID 30888650 DOI: 10.1007/978-981-13-3681-2_4