David S. Knopman, MD - Publications

Affiliations: 
Neurology Mayo Clinic, Rochester, MN, United States 
Area:
http://www.researchprofiles.collexis.com/jad/expert.asp?u_id=112
Website:
http://www.mayoclinic.org/bio/13632736.html

500 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2023 Corriveau-Lecavalier N, Botha H, Graff-Radford J, Switzer AR, Przybelski SA, Wiste HJ, Murray ME, Reichard RR, Dickson DW, Nguyen AT, Ramanan VK, McCarter SJ, Boeve BF, Machulda MM, Fields JA, ... ... Knopman DS, et al. A limbic-predominant amnestic neurodegenerative syndrome associated with TDP-43 pathology. Medrxiv : the Preprint Server For Health Sciences. PMID 38045300 DOI: 10.1101/2023.11.19.23298314  0.325
2023 Wang Y, Sharrett AR, Schneider ALC, Knopman D, Hu J, Gottesman R, Sullivan KJ, Coresh J. Timing of cognitive test score decline prior to incident dementia diagnosis in Blacks and Whites: The Atherosclerosis Risk in Communities Neurocognitive Study (ARIC-NCS). Neuroepidemiology. PMID 37918374 DOI: 10.1159/000533851  0.377
2023 Corriveau-Lecavalier N, Barnard LR, Botha H, Graff-Radford J, Ramanan VK, Lee J, Dicks E, Rademakers R, Boeve BF, Machulda MM, Fields JA, Dickson DW, Graff-Radford N, Knopman DS, Lowe VJ, et al. Uncovering the distinct macro-scale anatomy of dysexecutive and behavioural degenerative diseases. Brain : a Journal of Neurology. PMID 37831661 DOI: 10.1093/brain/awad356  0.357
2023 Schwarz CG, Kremers WK, Weigand SD, Prakaashana CM, Senjem ML, Przybelski SA, Lowe VJ, Gunter JL, Kantarci K, Vemuri P, Graff-Radford J, Petersen RC, Knopman DS, Jack CR. Effects of de-facing software mri_reface on utility of imaging biomarkers used in Alzheimer's disease research. Neuroimage. Clinical. 40: 103507. PMID 37703605 DOI: 10.1016/j.nicl.2023.103507  0.301
2023 Estades Ayuso V, Pickles S, Todd T, Yue M, Jansen-West K, Song Y, González Bejarano J, Rawlinson B, DeTure M, Graff-Radford NR, Boeve BF, Knopman DS, Petersen RC, Dickson DW, Josephs KA, et al. TDP-43-regulated cryptic RNAs accumulate in Alzheimer's disease brains. Molecular Neurodegeneration. 18: 57. PMID 37605276 DOI: 10.1186/s13024-023-00646-z  0.302
2023 Ramanan VK, Graff-Radford J, Syrjanen J, Shir D, Algeciras-Schimnich A, Lucas J, Martens YA, Carrasquillo MM, Day GS, Ertekin-Taner N, Lachner C, Willis FB, Knopman DS, Jack CR, Petersen RC, et al. Association of Plasma Biomarkers of Alzheimer Disease With Cognition and Medical Comorbidities in a Biracial Cohort. Neurology. PMID 37580163 DOI: 10.1212/WNL.0000000000207675  0.353
2023 Knopman DS, Hershey L. Implications of the Approval of Lecanemab for Alzheimer Disease Patient Care: Incremental Step or Paradigm Shift. Neurology. PMID 37295957 DOI: 10.1212/WNL.0000000000207438  0.343
2023 Bermudez C, Graff-Radford J, Syrjanen JA, Stricker NH, Algeciras-Schimnich A, Kouri N, Kremers WK, Petersen RC, Jack CR, Knopman DS, Dickson DW, Nguyen AT, Reichard RR, Murray ME, Mielke MM, et al. Plasma biomarkers for prediction of Alzheimer's disease neuropathologic change. Acta Neuropathologica. PMID 37269398 DOI: 10.1007/s00401-023-02594-w  0.314
2023 Tian J, Raghavan Pillai SK, Reid RI, Przybelski SA, Lesnick TG, Gebre RK, Graff-Radford J, Schwarz CG, Lowe VJ, Kantarci K, Knopman DS, Petersen RC, Jack CR, Vemuri P. White Matter Degeneration Pathways Associated With Tau Deposition in Alzheimer Disease. Neurology. PMID 37068958 DOI: 10.1212/WNL.0000000000207250  0.362
2023 Corriveau-Lecavalier N, Gunter JL, Kamykowski M, Dicks E, Botha H, Kremers WK, Graff-Radford J, Wiepert DA, Schwarz CG, Yacoub E, Knopman DS, Boeve BF, Ugurbil K, Petersen RC, Jack CR, et al. Default mode network failure and neurodegeneration across aging and amnestic and dysexecutive Alzheimer's disease. Brain Communications. 5: fcad058. PMID 37013176 DOI: 10.1093/braincomms/fcad058  0.319
2023 Knopman DS. Lecanemab reduces brain amyloid-β and delays cognitive worsening. Cell Reports. Medicine. 4: 100982. PMID 36948153 DOI: 10.1016/j.xcrm.2023.100982  0.367
2023 Corriveau-Lecavalier N, Barnard LR, Lee J, Dicks E, Botha H, Graff-Radford J, Machulda MM, Boeve BF, Knopman DS, Lowe VJ, Petersen RC, Jack CR, Jones DT. Deciphering the clinico-radiological heterogeneity of dysexecutive Alzheimer's disease. Cerebral Cortex (New York, N.Y. : 1991). PMID 36721911 DOI: 10.1093/cercor/bhad017  0.302
2022 Lee J, Burkett BJ, Min HK, Senjem ML, Lundt ES, Botha H, Graff-Radford J, Barnard LR, Gunter JL, Schwarz CG, Kantarci K, Knopman DS, Boeve BF, Lowe VJ, Petersen RC, et al. Deep learning-based brain age prediction in normal aging and dementia. Nature Aging. 2: 412-424. PMID 37118071 DOI: 10.1038/s43587-022-00219-7  0.338
2022 Stricker NH, Twohy EL, Albertson SM, Karstens AJ, Kremers WK, Machulda MM, Fields JA, Jack CR, Knopman DS, Mielke MM, Petersen RC. Mayo-PACC: A parsimonious preclinical Alzheimer's disease cognitive composite comprised of public-domain measures to facilitate clinical translation. Alzheimer's & Dementia : the Journal of the Alzheimer's Association. PMID 36565459 DOI: 10.1002/alz.12895  0.31
2022 Ferreira D, Przybelski SA, Lesnick TG, Schwarz CG, Diaz-Galvan P, Graff-Radford J, Senjem ML, Fields JA, Knopman DS, Jones DT, Savica R, Ferman TJ, Graff-Radford N, Lowe VJ, Jack CR, et al. Cross-sectional Associations of β-Amyloid, Tau, and Cerebrovascular Biomarkers With Neurodegeneration in Probable Dementia With Lewy Bodies. Neurology. PMID 36443011 DOI: 10.1212/WNL.0000000000201579  0.301
2022 Butts AM, Machulda MM, Martin P, Przybelski SA, Duffy JR, Graff-Radford J, Knopman DS, Petersen RC, Jack CR, Lowe VJ, Josephs KA, Whitwell JL. Temporal Cortical Thickness and Cognitive Associations among Typical and Atypical Phenotypes of Alzheimer's Disease. Journal of Alzheimer's Disease Reports. 6: 479-491. PMID 36186727 DOI: 10.3233/ADR-220010  0.385
2022 Pham NTT, Graff-Radford J, Machulda MM, Spychalla AJ, Schwarz CG, Senjem ML, Lowe VJ, Vemuri P, Kantarci K, Knopman DS, Petersen RC, Jack CR, Josephs KA, Whitwell JL. Regional white matter hyperintensities in posterior cortical atrophy and logopenic progressive aphasia. Neurobiology of Aging. 119: 46-55. PMID 35970009 DOI: 10.1016/j.neurobiolaging.2022.07.008  0.329
2022 Kamath V, Senjem ML, Spychalla AJ, Chen H, Palta P, Mosley TH, Windham BG, Griswold M, Knopman DS, Gottesman RF, Jack CR, Sharrett AR, Schneider ALC. The Neuroanatomic Correlates of Olfactory Identification Impairment in Healthy Older Adults and in Persons with Mild Cognitive Impairment. Journal of Alzheimer's Disease : Jad. PMID 35871337 DOI: 10.3233/JAD-220228  0.364
2022 Ramanan VK, Heckman MG, Przybelski SA, Lesnick TG, Lowe VJ, Graff-Radford J, Mielke M, Jack CR, Knopman DS, Petersen RC, Ross OA, Vemuri P. Polygenic Scores of Alzheimer's Disease Risk Genes Add Only Modestly to APOE in Explaining Variation in Amyloid PET Burden. Journal of Alzheimer's Disease : Jad. PMID 35811524 DOI: 10.3233/JAD-220164  0.336
2022 Gottesman RF, Wu A, Coresh J, Knopman DS, Jack CR, Rahmim A, Sharrett AR, Spira AP, Wong DF, Wagenknecht LE, Hughes TM, Walker KA, Mosley TH. Associations of vascular risk and amyloid burden with subsequent dementia. Annals of Neurology. PMID 35732594 DOI: 10.1002/ana.26447  0.359
2022 Nelson PT, Brayne C, Flanagan ME, Abner EL, Agrawal S, Attems J, Castellani RJ, Corrada MM, Cykowski MD, Di J, Dickson DW, Dugger BN, Ervin JF, Fleming J, Graff-Radford J, ... ... Knopman DS, et al. Frequency of LATE neuropathologic change across the spectrum of Alzheimer's disease neuropathology: combined data from 13 community-based or population-based autopsy cohorts. Acta Neuropathologica. PMID 35697880 DOI: 10.1007/s00401-022-02444-1  0.408
2022 Vassilaki M, Aakre JA, Castillo A, Chamberlain AM, Wilson PM, Kremers WK, Mielke MM, Geda YE, Machulda MM, Alhurani RE, Graff-Radford J, Vemuri P, Lowe VJ, Jack CR, Knopman DS, et al. Association of neighborhood socioeconomic disadvantage and cognitive impairment. Alzheimer's & Dementia : the Journal of the Alzheimer's Association. PMID 35666244 DOI: 10.1002/alz.12702  0.352
2022 Orlando A, Sharrett AR, Schneider ALC, Gottesman RF, Knopman DS, Rawlings A, Mosley TH, Jack CR, Wong D, Pike JR, Coresh J. Brain Imaging Features Associated with 20-Year Cognitive Decline in a Community-Based Multiethnic Cohort Without Dementia. Neuroepidemiology. PMID 35500554 DOI: 10.1159/000524731  0.37
2022 Kantarci K, Nedelska Z, Chen Q, Senjem ML, Schwarz CG, Gunter JL, Przybelski SA, Lesnick TG, Kremers WK, Fields JA, Graff-Radford J, Savica R, Jones D, Botha H, Knopman DS, et al. Longitudinal atrophy in prodromal dementia with Lewy bodies points to cholinergic degeneration. Brain Communications. 4: fcac013. PMID 35415608 DOI: 10.1093/braincomms/fcac013  0.362
2022 Ramanan VK, Heckman MG, Lesnick TG, Przybelski SA, Cahn EJ, Kosel ML, Murray ME, Mielke MM, Botha H, Graff-Radford J, Jones DT, Lowe VJ, Machulda MM, Jack CR, Knopman DS, et al. Tau polygenic risk scoring: a cost-effective aid for prognostic counseling in Alzheimer's disease. Acta Neuropathologica. PMID 35412102 DOI: 10.1007/s00401-022-02419-2  0.353
2022 Barker MS, Gottesman RT, Manoochehri M, Chapman S, Appleby BS, Brushaber D, Devick KL, Dickerson BC, Domoto-Reilly K, Fields JA, Forsberg LK, Galasko DR, Ghoshal N, Goldman J, Graff-Radford NR, ... ... Knopman DS, et al. Proposed research criteria for prodromal behavioural variant frontotemporal dementia. Brain : a Journal of Neurology. PMID 35349636 DOI: 10.1093/brain/awab365  0.317
2022 Jack CR, Therneau TM, Lundt ES, Wiste HJ, Mielke MM, Knopman DS, Graff-Radford J, Lowe VJ, Vemuri P, Schwarz CG, Senjem ML, Gunter JL, Petersen RC. Long-term associations between amyloid positron emission tomography, sex, apolipoprotein E and incident dementia and mortality among individuals without dementia: hazard ratios and absolute risk. Brain Communications. 4: fcac017. PMID 35310829 DOI: 10.1093/braincomms/fcac017  0.334
2022 Chen Q, Przybelski SA, Senjem ML, Schwarz CG, Lesnick TG, Botha H, Knopman DS, Graff-Radford J, Savica R, Jones DT, Fields JA, Jain MK, Graff-Radford NR, Ferman TJ, Kremers WK, et al. Longitudinal Tau Positron Emission Tomography in Dementia with Lewy Bodies. Movement Disorders : Official Journal of the Movement Disorder Society. PMID 35261094 DOI: 10.1002/mds.28973  0.318
2022 Corriveau-Lecavalier N, Machulda MM, Botha H, Graff-Radford J, Knopman DS, Lowe VJ, Fields JA, Stricker NH, Boeve BF, Jack CR, Petersen RC, Jones DT. Phenotypic subtypes of progressive dysexecutive syndrome due to Alzheimer's disease: a series of clinical cases. Journal of Neurology. PMID 35211780 DOI: 10.1007/s00415-022-11025-x  0.326
2022 Saboo KV, Hu C, Varatharajah Y, Przybelski SA, Reid RI, Schwarz CG, Graff-Radford J, Knopman DS, Machulda MM, Mielke MM, Petersen RC, Arnold PM, Worrell GA, Jones DT, Jack CR, et al. Deep learning identifies brain structures that predict cognition and explain heterogeneity in cognitive aging. Neuroimage. 119020. PMID 35196565 DOI: 10.1016/j.neuroimage.2022.119020  0.338
2022 Windham BG, Parker SB, Zhu X, Gabriel KP, Palta P, Sullivan KJ, Parker KG, Knopman DS, Gottesman RF, Griswold ME, Mosley TH. Endurance and gait speed relationships with mild cognitive impairment and dementia. Alzheimer's & Dementia (Amsterdam, Netherlands). 14: e12281. PMID 35155735 DOI: 10.1002/dad2.12281  0.322
2022 Raghavan S, Przybelski SA, Reid RI, Lesnick TG, Ramanan VK, Botha H, Matchett BJ, Murray ME, Reichard RR, Knopman DS, Graff-Radford J, Jones DT, Lowe VJ, Mielke MM, Machulda MM, et al. White matter damage due to vascular, tau, and TDP-43 pathologies and its relevance to cognition. Acta Neuropathologica Communications. 10: 16. PMID 35123591 DOI: 10.1186/s40478-022-01319-6  0.339
2021 Gomez GT, Gottesman RF, Gabriel KP, Palta P, Gross AL, Soldan A, Albert MS, Sullivan KJ, Jack CR, Knopman DS, Windham BG, Walker KA. The association of motoric cognitive risk with incident dementia and neuroimaging characteristics: The Atherosclerosis Risk in Communities Study. Alzheimer's & Dementia : the Journal of the Alzheimer's Association. PMID 34786837 DOI: 10.1002/alz.12412  0.314
2021 Schwarz CG, Knopman DS, Ramanan VK, Lowe VJ, Wiste HJ, Cogswell PM, Utianski RL, Senjem ML, Gunter JR, Vemuri P, Petersen RC, Jack CR. Longitudinally Increasing Elevated Asymmetric Flortaucipir Binding in a Cognitively Unimpaired Amyloid-Negative Older Individual. Journal of Alzheimer's Disease : Jad. PMID 34776445 DOI: 10.3233/jad-215052  0.306
2021 Powell DS, Kuo PL, Qureshi R, Coburn SB, Knopman DS, Palta P, Gottesman R, Griswold M, Albert M, Deal JA, Gross AL. The Relationship of ε4, Race, and Sex on the Age of Onset and Risk of Dementia. Frontiers in Neurology. 12: 735036. PMID 34744974 DOI: 10.3389/fneur.2021.735036  0.321
2021 Pudumjee SB, Lundt ES, Albertson SM, Machulda MM, Kremers WK, Jack CR, Knopman DS, Petersen RC, Mielke MM, Stricker NH. A Comparison of Cross-Sectional and Longitudinal Methods of Defining Objective Subtle Cognitive Decline in Preclinical Alzheimer's Disease Based on Cogstate One Card Learning Accuracy Performance. Journal of Alzheimer's Disease : Jad. PMID 34366338 DOI: 10.3233/JAD-210251  0.332
2021 Sullivan KJ, Blackshear C, Simino J, Tin A, Walker KA, Sharrett AR, Younkin S, Gottesman RF, Mielke MM, Knopman D, Windham BG, Griswold ME, Mosley TH. Association of Midlife Plasma Amyloid-β Levels With Cognitive Impairment in Late Life: The ARIC Neurocognitive Study. Neurology. PMID 34349010 DOI: 10.1212/WNL.0000000000012482  0.314
2021 Kantarci K, Boeve BF, Przybelski SA, Lesnick TG, Chen Q, Fields J, Schwarz CG, Senjem ML, Gunte JL, Jack CR, Min P, Jain M, Migayawa T, Savica R, Graff-Radford J, ... ... Knopman DS, et al. FDG PET metabolic signatures distinguishing prodromal DLB and prodromal AD. Neuroimage. Clinical. 31: 102754. PMID 34252877 DOI: 10.1016/j.nicl.2021.102754  0.338
2021 Schumacher J, Gunter JL, Przybelski SA, Jones DT, Graff-Radford J, Savica R, Schwarz CG, Senjem ML, Jack CR, Lowe VJ, Knopman DS, Fields JA, Kremers WK, Petersen RC, Graff-Radford NR, et al. Dementia with Lewy bodies: association of Alzheimer pathology with functional connectivity networks. Brain : a Journal of Neurology. PMID 34114602 DOI: 10.1093/brain/awab218  0.308
2021 Knopman DS, Amieva H, Petersen RC, Chételat G, Holtzman DM, Hyman BT, Nixon RA, Jones DT. Alzheimer disease. Nature Reviews. Disease Primers. 7: 33. PMID 33986301 DOI: 10.1038/s41572-021-00269-y  0.398
2021 Vemuri P, Graff-Radford J, Lesnick TG, Przybelski SA, Reid RI, Reddy AL, Lowe VJ, Mielke MM, Machulda MM, Petersen RC, Knopman DS, Jack CR. White matter abnormalities are key components of cerebrovascular disease impacting cognitive decline. Brain Communications. 3: fcab076. PMID 33937772 DOI: 10.1093/braincomms/fcab076  0.325
2021 Ramanan VK, Lesnick TG, Przybelski SA, Heckman MG, Knopman DS, Graff-Radford J, Lowe VJ, Machulda MM, Mielke MM, Jack CR, Petersen RC, Ross OA, Vemuri P. Coping with brain amyloid: genetic heterogeneity and cognitive resilience to Alzheimer's pathophysiology. Acta Neuropathologica Communications. 9: 48. PMID 33757599 DOI: 10.1186/s40478-021-01154-1  0.409
2021 Krell-Roesch J, Syrjanen JA, Machulda MM, Christianson TJ, Kremers WK, Mielke MM, Knopman DS, Petersen RC, Vassilaki M, Geda YE. Neuropsychiatric symptoms and the outcome of cognitive trajectories in older adults free of dementia: The Mayo Clinic Study of Aging. International Journal of Geriatric Psychiatry. PMID 33724517 DOI: 10.1002/gps.5528  0.325
2021 Alden EC, Pudumjee SB, Lundt ES, Albertson SM, Machulda MM, Kremers WK, Jack CR, Knopman DS, Petersen RC, Mielke MM, Stricker NH. Diagnostic accuracy of the Cogstate Brief Battery for prevalent MCI and prodromal AD (MCI A T ) in a population-based sample. Alzheimer's & Dementia : the Journal of the Alzheimer's Association. PMID 33650308 DOI: 10.1002/alz.12219  0.347
2021 Cogswell PM, Weigand SD, Wiste HJ, Gunter JL, Graff-Radford J, Jones DT, Schwarz CG, Senjem ML, Knopman DS, Petersen RC, Jack CR. CSF Dynamics as a Predictor of Cognitive Progression. Neuroimage. 117899. PMID 33631332 DOI: 10.1016/j.neuroimage.2021.117899  0.371
2021 Chen Q, Lowe VJ, Boeve BF, Przybelski SA, Miyagawa T, Senjem ML, Jack CR, Lesnick TG, Kremers WK, Fields JA, Min HK, Schwarz CG, Gunter JL, Graff-Radford J, Savica R, ... Knopman DS, et al. Mild Cognitive Impairment at Risk for Lewy Body Dementia. Neurology. PMID 33408148 DOI: 10.1212/WNL.0000000000011454  0.38
2020 Josephs KA, Martin PR, Weigand SD, Tosakulwong N, Buciuc M, Murray ME, Petrucelli L, Senjem ML, Spychalla AJ, Knopman DS, Boeve BF, Petersen RC, Parisi JE, Dickson DW, Jack CR, et al. Protein contributions to brain atrophy acceleration in Alzheimer's disease and primary age-related tauopathy. Brain : a Journal of Neurology. PMID 33150361 DOI: 10.1093/brain/awaa299  0.303
2020 Jack CR, Wiste HJ, Weigand SD, Therneau TM, Lowe VJ, Knopman DS, Botha H, Graff-Radford J, Jones DT, Ferman TJ, Boeve BF, Kantarci K, Vemuri P, Mielke MM, Whitwell J, et al. Predicting future rates of tau accumulation on PET. Brain : a Journal of Neurology. PMID 33094327 DOI: 10.1093/brain/awaa248  0.4
2020 Knopman DS, Lundt ES, Therneau TM, Albertson SM, Gunter JL, Senjem ML, Schwarz CG, Mielke MM, Machulda MM, Boeve BF, Jones DT, Graff-Radford J, Vemuri P, Kantarci K, Lowe VJ, et al. Association of Initial β-Amyloid Levels With Subsequent Flortaucipir Positron Emission Tomography Changes in Persons Without Cognitive Impairment. Jama Neurology. PMID 33074304 DOI: 10.1001/jamaneurol.2020.3921  0.371
2020 Cogswell PM, Wiste HJ, Senjem ML, Gunter JL, Weigand SD, Schwarz CG, Arani A, Therneau TM, Lowe VJ, Knopman DS, Botha H, Graff-Radford J, Jones DT, Kantarci K, Vemuri P, et al. Associations of Quantitative Susceptibility Mapping with Alzheimer's Disease Clinical and Imaging Markers. Neuroimage. 117433. PMID 33035667 DOI: 10.1016/j.neuroimage.2020.117433  0.353
2020 Raghavan S, Przybelski SA, Reid RI, Graff-Radford J, Lesnick TG, Zuk SM, Knopman DS, Machulda MM, Mielke MM, Petersen RC, Jack CR, Vemuri P. Reduced fractional anisotropy of the genu of the corpus callosum as a cerebrovascular disease marker and predictor of longitudinal cognition in MCI. Neurobiology of Aging. 96: 176-183. PMID 33022474 DOI: 10.1016/J.Neurobiolaging.2020.09.005  0.459
2020 Bennett DA, Knopman DS. Extending AD biomarker studies into the Hispanic community. Neurology. PMID 32847949 DOI: 10.1212/Wnl.0000000000010714  0.436
2020 Prudencio M, Humphrey J, Pickles S, Brown AL, Hill SE, Kachergus J, Shi J, Heckman M, Spiegel M, Cook C, Song Y, Yue M, Daughrity L, Carlomagno Y, Jansen-West K, ... ... Knopman DS, et al. Truncated stathmin-2 is a marker of TDP-43 pathology in frontotemporal dementia. The Journal of Clinical Investigation. PMID 32790644 DOI: 10.1172/Jci139741  0.371
2020 Townley RA, Graff-Radford J, Mantyh WG, Botha H, Polsinelli AJ, Przybelski SA, Machulda MM, Makhlouf AT, Senjem ML, Murray ME, Reichard RR, Savica R, Boeve BF, Drubach DA, Josephs KA, ... Knopman DS, et al. Progressive dysexecutive syndrome due to Alzheimer's disease: a description of 55 cases and comparison to other phenotypes. Brain Communications. 2: fcaa068. PMID 32671341 DOI: 10.1093/braincomms/fcaa068  0.367
2020 Krell-Roesch J, Syrjanen JA, Vassilaki M, Lowe VJ, Vemuri P, Mielke MM, Machulda MM, Stokin GB, Christianson TJ, Kremers WK, Jack CR, Knopman DS, Petersen RC, Geda YE. Brain Regional Glucose Metabolism, Neuropsychiatric Symptoms, and the Risk of Incident Mild Cognitive Impairment: The Mayo Clinic Study of Aging. The American Journal of Geriatric Psychiatry : Official Journal of the American Association For Geriatric Psychiatry. PMID 32646634 DOI: 10.1016/J.Jagp.2020.06.006  0.364
2020 Bejanin A, Tammewar G, Marx G, Cobigo Y, Iaccarino L, Kornak J, Staffaroni AM, Dickerson BC, Boeve BF, Knopman DS, Gorno-Tempini M, Miller BL, Jagust WJ, Boxer AL, Rosen HJ, et al. Longitudinal structural and metabolic changes in frontotemporal dementia. Neurology. PMID 32591470 DOI: 10.1212/Wnl.0000000000009760  0.311
2020 Caselli RJ, Knopman DS, Bu G. An agnostic reevaluation of the amyloid cascade hypothesis of Alzheimer's disease pathogenesis: The role of APP homeostasis. Alzheimer's & Dementia : the Journal of the Alzheimer's Association. PMID 32588983 DOI: 10.1002/Alz.12124  0.355
2020 Sintini I, Graff-Radford J, Senjem ML, Schwarz CG, Machulda MM, Martin PR, Jones DT, Boeve BF, Knopman DS, Kantarci K, Petersen RC, Jack CR, Lowe VJ, Josephs KA, Whitwell JL. Longitudinal neuroimaging biomarkers differ across Alzheimer's disease phenotypes. Brain : a Journal of Neurology. PMID 32572464 DOI: 10.1093/Brain/Awaa155  0.431
2020 Ferman TJ, Aoki N, Boeve BF, Aakre JA, Kantarci K, Graff-Radford J, Parisi JE, Van Gerpen JA, Graff-Radford NR, Uitti RJ, Pedraza O, Murray ME, Wszolek ZK, Reichard RR, Fields JA, ... ... Knopman DS, et al. Subtypes of dementia with Lewy bodies are associated with α-synuclein and tau distribution. Neurology. PMID 32561678 DOI: 10.1212/Wnl.0000000000009763  0.349
2020 Stricker NH, Lundt ES, Albertson SM, Machulda MM, Pudumjee SB, Kremers WK, Jack CR, Knopman DS, Petersen RC, Mielke MM. Diagnostic and Prognostic Accuracy of the Cogstate Brief Battery and Auditory Verbal Learning Test in Preclinical Alzheimer's Disease and Incident Mild Cognitive Impairment: Implications for Defining Subtle Objective Cognitive Impairment. Journal of Alzheimer's Disease : Jad. PMID 32538841 DOI: 10.3233/Jad-200087  0.441
2020 Li D, Hagen C, Bui HH, Knopman D, Jack CR, Machulda M, Petersen RC, Mielke MM. Associations between cerebrospinal fluid total phosphatidylcholines, neurodegeneration, cognitive decline, and risk of mild cognitive impairment in the Mayo Clinic Study of Aging. Neurobiology of Aging. 93: 52-54. PMID 32450444 DOI: 10.1016/J.Neurobiolaging.2020.04.020  0.427
2020 Palta P, Heiss G, Sharrett AR, Pettee Gabriel K, Walker K, Evenson KR, Knopman D, Mosley TH, Wong D, Gottesman RF. Mid- and Late-Life Leisure-Time Physical Activity and Global Brain Amyloid Burden: The Atherosclerosis Risk in Communities (ARIC)-PET Study. Journal of Alzheimer's Disease : Jad. PMID 32444546 DOI: 10.3233/Jad-200152  0.318
2020 Choudhury P, Scharf EL, Paolini MA, Graff-Radford J, Alden EC, Machulda MM, Jones DT, Fields JA, Murray ME, Graff-Radford NR, Constantopoulos E, Reichard RR, Knopman DS, Duffy JR, Dickson DW, et al. Pick's disease: clinicopathologic characterization of 21 cases. Journal of Neurology. PMID 32440921 DOI: 10.1007/S00415-020-09927-9  0.352
2020 Scheppach JB, Coresh J, Wu A, Gottesman RF, Mosley TH, Knopman DS, Grams ME, Sharrett AR, Koton S. Albuminuria and Estimated GFR as Risk Factors of Dementia in Midlife and Older Age: Findings From the ARIC Study. American Journal of Kidney Diseases : the Official Journal of the National Kidney Foundation. PMID 32428540 DOI: 10.1053/J.Ajkd.2020.03.015  0.338
2020 Knopman D, Lemere CA, Lamb BT, Craft S, Gitlin LN, Golde TE, Pericak-Vance M, Sano M, Schellenberg G, Schneider JA, Zheng H, Khachaturian Z, Snyder HM, Carrillo MC. Scientific Advising and Reviewing: On strengthening the bond between the Alzheimer's Association and the scientific community. Alzheimer's & Dementia : the Journal of the Alzheimer's Association. PMID 32426924 DOI: 10.1002/Alz.12059  0.323
2020 Machulda MM, Lundt ES, Albertson SM, Spychalla AJ, Schwarz CG, Mielke MM, Jack CR, Kremers WK, Vemuri P, Knopman DS, Jones DT, Bondi MW, Petersen RC. Cortical atrophy patterns of incident MCI subtypes in the Mayo Clinic Study of Aging. Alzheimer's & Dementia : the Journal of the Alzheimer's Association. PMID 32418367 DOI: 10.1002/Alz.12108  0.39
2020 Utianski RL, Botha H, Whitwell JL, Martin PR, Schwarz CG, Duffy JR, Clark HM, Spychalla AJ, Senjem ML, Petersen RC, Knopman DS, Jack CR, Lowe VJ, Josephs KA. Longitudinal flortaucipir ([F]AV-1451) PET uptake in semantic dementia. Neurobiology of Aging. 92: 135-140. PMID 32417749 DOI: 10.1016/J.Neurobiolaging.2020.04.010  0.31
2020 Buciuc M, Whitwell JL, Tosakulwong N, Weigand SD, Murray ME, Boeve BF, Knopman DS, Parisi JE, Petersen RC, Dickson DW, Josephs KA. Association between transactive response DNA-binding protein of 43 kDa type and cognitive resilience to Alzheimer's disease: a case-control study. Neurobiology of Aging. 92: 92-97. PMID 32408057 DOI: 10.1016/J.Neurobiolaging.2020.04.001  0.426
2020 Liu P, Smith BR, Montonye ML, Kemper LJ, Leinonen-Wright K, Nelson KM, Higgins L, Guerrero CR, Markowski TW, Zhao X, Petersen AJ, Knopman DS, Petersen RC, Ashe KH. Author Correction: A soluble truncated tau species related to cognitive dysfunction is elevated in the brain of cognitively impaired human individuals. Scientific Reports. 10: 8077. PMID 32398746 DOI: 10.1038/S41598-020-65178-8  0.38
2020 Vassilaki M, Aakre JA, Kremers WK, Lesnick TG, Mielke MM, Geda YE, Machulda MM, Knopman DS, Butler L, Traber M, Vemuri P, Lowe VJ, Jack CR, Roberts RO, Petersen RC. Brain amyloid, cortical thickness, and changes in activities of daily living. Annals of Clinical and Translational Neurology. 7: 474-485. PMID 32314554 DOI: 10.1002/Acn3.51010  0.431
2020 Josephs KA, Tosakulwong N, Graff-Radford J, Weigand SD, Buciuc M, Machulda MM, Jones DT, Schwarz CG, Senjem ML, Ertekin-Taner N, Kantarci K, Boeve BF, Knopman DS, Jack CR, Petersen RC, et al. MRI and flortaucipir relationships in Alzheimer's phenotypes are heterogeneous. Annals of Clinical and Translational Neurology. PMID 32293805 DOI: 10.1002/Acn3.51038  0.374
2020 Kruthiventi SC, Laporta ML, Deljou A, Knopman DS, Petersen RC, Schroeder DR, Sprung J, Weingarten TN. Preoperative cognitive impairment associated with oversedation during recovery from anesthesia. Journal of Anesthesia. 34: 390-396. PMID 32222908 DOI: 10.1007/S00540-020-02764-0  0.363
2020 Carvalho DZ, St Louis EK, Schwarz CG, Lowe VJ, Boeve BF, Przybelski SA, Reddy A, Mielke MM, Knopman DS, Petersen RC, Jack CR, Vemuri P. Witnessed apneas are associated with elevated tau-PET levels in cognitively unimpaired elderly. Neurology. PMID 32217775 DOI: 10.1212/Wnl.0000000000009315  0.367
2020 Knopman DS, Petersen RC. The quest for dementia prevention does not include an aspirin a day. Neurology. 95: 105-106. PMID 32213641 DOI: 10.1212/Wnl.0000000000009278  0.416
2020 Sprung J, Warner DO, Knopman DS, Petersen RC, Mielke MM, Jack CR, Lowe VJ, Martin DP, Hanson AC, Schroeder DR, Przybelski SA, Schulte PJ, Weingarten TN, Vemuri P. Exposure to surgery with general anaesthesia during adult life is not associated with increased brain amyloid deposition in older adults. British Journal of Anaesthesia. PMID 32171548 DOI: 10.1016/J.Bja.2020.01.015  0.314
2020 Liu P, Smith BR, Montonye ML, Kemper LJ, Leinonen-Wright K, Nelson KM, Higgins L, Guerrero CR, Markowski TW, Zhao X, Petersen AJ, Knopman DS, Petersen RC, Ashe KH. A soluble truncated tau species related to cognitive dysfunction is elevated in the brain of cognitively impaired human individuals. Scientific Reports. 10: 3869. PMID 32123248 DOI: 10.1038/S41598-020-60777-X  0.414
2020 Vassilaki M, Syrjanen JA, Kremers WK, Hagen PT, Knopman DS, Mielke MM, Geda YE, Alhurani RE, Machulda MM, Roberts RO, Petersen RC. Medical Doctors and Dementia: A Longitudinal Study. Journal of the American Geriatrics Society. PMID 32086949 DOI: 10.1111/Jgs.16375  0.316
2020 Giebel CM, Knopman D, Mioshi E, Khondoker M. Distinguishing Frontotemporal Dementia From Alzheimer Disease Through Everyday Function Profiles: Trajectories of Change: Journal of Geriatric Psychiatry and Neurology. 89198872090179. PMID 32054376 DOI: 10.1177/0891988720901791  0.354
2020 Buciuc M, Whitwell JL, Boeve BF, Ferman TJ, Graff-Radford J, Savica R, Kantarci K, Fields JA, Knopman DS, Petersen RC, Parisi JE, Murray ME, Dickson DW, Josephs KA. TDP-43 is associated with a reduced likelihood of rendering a clinical diagnosis of dementia with Lewy bodies in autopsy-confirmed cases of transitional/diffuse Lewy body disease. Journal of Neurology. PMID 32006160 DOI: 10.1007/S00415-020-09718-2  0.345
2020 Zeydan B, Lowe VJ, Reichard RR, Przybelski SA, Lesnick TG, Schwarz CG, Senjem ML, Gunter JL, Parisi JE, Machulda MM, Vemuri P, Mielke MM, Knopman DS, Petersen RC, Jack CR, et al. Imaging Biomarkers of Alzheimer's Disease in Multiple Sclerosis. Annals of Neurology. PMID 31970802 DOI: 10.1002/Ana.25684  0.334
2020 Arenaza-Urquijo EM, Przybelski SA, Machulda MM, Knopman DS, Lowe VJ, Mielke MM, Reddy AL, Geda YE, Jack CR, Petersen RC, Vemuri P. Better stress coping associated with lower tau in amyloid-positive cognitively unimpaired older adults. Neurology. PMID 31964689 DOI: 10.1212/Wnl.0000000000008979  0.37
2020 Buciuc M, Wennberg AM, Weigand SD, Murray ME, Senjem ML, Spychalla AJ, Boeve BF, Knopman DS, Jack CR, Kantarci K, Parisi JE, Dickson DW, Petersen RC, Whitwell JL, Josephs KA. Effect Modifiers of TDP-43 Associated Hippocampal Atrophy Rates in Patients with Alzheimer's Disease Neuropathological Changes. Journal of Alzheimer's Disease : Jad. PMID 31929165 DOI: 10.3233/Jad-191040  0.38
2020 Staffaroni AM, Bajorek L, Casaletto KB, Cobigo Y, Goh SM, Wolf A, Heuer HW, Elahi FM, Ljubenkov PA, Dever R, Kornak J, Appleby B, Bove J, Bordelon Y, Brannelly P, ... ... Knopman DS, et al. Assessment of executive function declines in presymptomatic and mildly symptomatic familial frontotemporal dementia: NIH-EXAMINER as a potential clinical trial endpoint. Alzheimer's & Dementia : the Journal of the Alzheimer's Association. 16: 11-21. PMID 31914230 DOI: 10.1016/J.Jalz.2019.01.012  0.337
2020 Ramos EM, Dokuru DR, Van Berlo V, Wojta K, Wang Q, Huang AY, Deverasetty S, Qin Y, van Blitterswijk M, Jackson J, Appleby B, Bordelon Y, Brannelly P, Brushaber DE, Dickerson B, ... ... Knopman D, et al. Genetic screening of a large series of North American sporadic and familial frontotemporal dementia cases. Alzheimer's & Dementia : the Journal of the Alzheimer's Association. 16: 118-130. PMID 31914217 DOI: 10.1002/Alz.12011  0.328
2020 Krell-Roesch J, Syrjanen JA, Vassilaki M, Woll A, Kremers WK, Machulda MM, Mielke MM, Knopman DS, Petersen RC, Geda YE. Late-life Physical Exercise, Neuropsychiatric Symptoms And The Risk Of Incident Mild Cognitive Impairment: 1299 Board #6 May 28 9:30 AM - 11:30 AM Medicine and Science in Sports and Exercise. 52: 339-340. DOI: 10.1249/01.Mss.0000677440.85436.77  0.324
2020 Manemann SM, Knopman D, St. Sauver J, Bielinski SJ, Chamberlain AM, Weston SA, Jiang R, Roger VL. Abstract P475: Dementia and Heart Failure a Community Study Circulation. 141. DOI: 10.1161/Circ.141.Suppl_1.P475  0.367
2020 Palta P, Wei J, Wu A, Meyer M, Sharrett AR, Tanaka H, Knopman D, Kucharska-newton A, Hughes T, Matsushita K, Mosley T, HEISS GM. Abstract P425: Central Aortic Stiffening in Late-life and Odds of Dementia: The Atherosclerosis Risk in Communities Neurocognitive Study (ARIC-NCS) Circulation. 141. DOI: 10.1161/Circ.141.Suppl_1.P425  0.423
2020 Lu Y, Thomas AG, Selvin E, Palta P, Sharrett AR, Mosley T, Knopman D, Pike J, Loehr LR, HEISS GM. Abstract P424: Low Liver Enzymes, Cognitive Performance and Dementia. The Atherosclerosis Risk in Communities Neurocognitive Study (aric-ncs) Circulation. 141. DOI: 10.1161/Circ.141.Suppl_1.P424  0.424
2020 JOHANSEN MC, Mosley T, Knopman D, Wong D, Wagenknecht LE, Ndumele CE, Shah AM, Solomon S, Gottesman RF. Abstract MP77: Associations Between Atrial Cardiopathy and Cerebral Amyloid: The Aric Pet Study Circulation. 141. DOI: 10.1161/Circ.141.Suppl_1.Mp77  0.35
2020 Rawlings AM, Ballantyne CM, Gottesman RF, Hoogeveen RC, Hughes TM, Jack CR, Knopman D, McEvoy JW, Mosley T, Schneider AL, Sharrett AR, Selvin E. Abstract 14: Cardiac Biomarkers are Associated With Findings on Brain MRI in Older Adults: The Atherosclerosis Risk in Communities (ARIC) Study Circulation. 141. DOI: 10.1161/Circ.141.Suppl_1.14  0.35
2020 Deal JA, Power MC, Bandeen-Roche K, Griswold M, Knopman D, Mosley T, Walker K, Gottesman RF, Sharrett AR. Abstract 01: Retinal Microvascular Signs and White Matter MRI Findings: The Atherosclerosis Risk in Communities Neurocognitive Study Circulation. 141. DOI: 10.1161/Circ.141.Suppl_1.01  0.313
2019 Neth BJ, Graff-Radford J, Mielke MM, Przybelski SA, Lesnick TG, Schwarz CG, Reid RI, Senjem ML, Lowe VJ, Machulda MM, Petersen RC, Jr CRJ, Knopman DS, Vemuri P. Relationship Between Risk Factors and Brain Reserve in Late Middle Age: Implications for Cognitive Aging. Frontiers in Aging Neuroscience. 11: 355. PMID 31998113 DOI: 10.3389/Fnagi.2019.00355  0.352
2019 Kornak J, Fields J, Kremers W, Farmer S, Heuer HW, Forsberg L, Brushaber D, Rindels A, Dodge H, Weintraub S, Besser L, Appleby B, Bordelon Y, Bove J, Brannelly P, ... ... Knopman D, et al. Nonlinear Z-score modeling for improved detection of cognitive abnormality. Alzheimer's & Dementia (Amsterdam, Netherlands). 11: 797-808. PMID 31872042 DOI: 10.1016/J.Dadm.2019.08.003  0.343
2019 Kantarci K, Lowe VJ, Chen Q, Przybelski SA, Lesnick TG, Schwarz CG, Senjem ML, Gunter JL, Jack CR, Graff-Radford J, Jones DT, Knopman DS, Graff-Radford N, Ferman TJ, Parisi JE, et al. β-Amyloid PET and neuropathology in dementia with Lewy bodies. Neurology. PMID 31862783 DOI: 10.1212/Wnl.0000000000008818  0.365
2019 Gottesman RF, Mosley TH, Knopman DS, Hao Q, Wong D, Wagenknecht LE, Hughes TM, Qiao Y, Dearborn J, Wasserman BA. Association of Intracranial Atherosclerotic Disease With Brain β-Amyloid Deposition: Secondary Analysis of the ARIC Study. Jama Neurology. PMID 31860001 DOI: 10.1001/Jamaneurol.2019.4339  0.4
2019 Ghisays V, Goradia DD, Protas H, Bauer RJ, Devadas V, Tariot PN, Lowe VJ, Knopman DS, Petersen RC, Jack CR, Caselli RJ, Su Y, Chen K, Reiman EM. Brain imaging measurements of fibrillar amyloid-β burden, paired helical filament tau burden, and atrophy in cognitively unimpaired persons with two, one, and no copies of the APOE ε4 allele. Alzheimer's & Dementia : the Journal of the Alzheimer's Association. PMID 31831374 DOI: 10.1016/J.Jalz.2019.08.195  0.387
2019 Utianski RL, Martin PR, Botha H, Schwarz CG, Duffy JR, Petersen RC, Knopman DS, Clark HM, Butts AM, Machulda MM, Jack CR, Lowe VJ, Whitwell JL, Josephs KA. Longitudinal flortaucipir ([F]AV-1451) PET imaging in primary progressive apraxia of speech. Cortex; a Journal Devoted to the Study of the Nervous System and Behavior. 124: 33-43. PMID 31830664 DOI: 10.1016/J.Cortex.2019.11.002  0.384
2019 Moore KM, Nicholas J, Grossman M, McMillan CT, Irwin DJ, Massimo L, Van Deerlin VM, Warren JD, Fox NC, Rossor MN, Mead S, Bocchetta M, Boeve BF, Knopman DS, Graff-Radford NR, et al. Age at symptom onset and death and disease duration in genetic frontotemporal dementia: an international retrospective cohort study. The Lancet. Neurology. PMID 31810826 DOI: 10.1016/S1474-4422(19)30394-1  0.326
2019 Graff-Radford J, Lesnick T, Rabinstein AA, Gunter J, Aakre J, Przybelski SA, Spychalla AJ, Huston J, Brown RD, Mielke MM, Lowe VJ, Knopman DS, Petersen RC, Jack CR, Vemuri P, et al. Cerebral microbleed incidence, relationship to amyloid burden: The Mayo Clinic Study of Aging. Neurology. PMID 31801832 DOI: 10.1212/Wnl.0000000000008735  0.333
2019 Krell-Roesch J, Syrjanen JA, Vassilaki M, Barisch-Fritz B, Trautwein S, Boes K, Woll A, Kremers WK, Machulda MM, Mielke MM, Knopman DS, Petersen RC, Geda YE. Association of non-exercise physical activity in mid- and late-life with cognitive trajectories and the impact of APOE ε4 genotype status: the Mayo Clinic Study of Aging. European Journal of Ageing. 16: 491-502. PMID 31798373 DOI: 10.1007/S10433-019-00513-1  0.358
2019 Nedelska Z, Schwarz CG, Lesnick TG, Boeve BF, Przybelski SA, Lowe VJ, Kremers WK, Gunter JL, Senjem ML, Graff-Radford J, Ferman TJ, Fields JA, Knopman DS, Petersen RC, Jack CR, et al. Association of Longitudinal β-Amyloid Accumulation Determined by Positron Emission Tomography With Clinical and Cognitive Decline in Adults With Probable Lewy Body Dementia. Jama Network Open. 2: e1916439. PMID 31790563 DOI: 10.1001/jamanetworkopen.2019.16439  0.355
2019 Olney NT, Ong E, Goh SM, Bajorek L, Dever R, Staffaroni AM, Cobigo Y, Bock M, Chiang K, Ljubenkov P, Kornak J, Heuer HW, Wang P, Rascovsky K, Wolf A, ... ... Knopman DS, et al. Clinical and volumetric changes with increasing functional impairment in familial frontotemporal lobar degeneration. Alzheimer's & Dementia : the Journal of the Alzheimer's Association. PMID 31784375 DOI: 10.1016/J.Jalz.2019.08.196  0.31
2019 Crook JE, Gunter JL, Ball CT, Jones DT, Graff-Radford J, Knopman DS, Boeve BF, Petersen RC, Jack CR, Graff-Radford NR. Linear vs volume measures of ventricle size: Relation to present and future gait and cognition. Neurology. PMID 31748251 DOI: 10.1212/Wnl.0000000000008673  0.365
2019 Graff-Radford J, Gunter JL, Jones DT, Przybelski SA, Schwarz CG, Huston J, Lowe V, Elder BD, Machulda MM, Gunter NB, Petersen RC, Kantarci K, Vemuri P, Mielke MM, Knopman DS, et al. Cerebrospinal fluid dynamics disorders: Relationship to Alzheimer biomarkers and cognition. Neurology. PMID 31719134 DOI: 10.1212/Wnl.0000000000008616  0.401
2019 Mielke MM, Syrjanen JA, Blennow K, Zetterberg H, Skoog I, Vemuri P, Machulda MM, Graff-Radford J, Knopman DS, Jack CR, Petersen RC, Kern S. Comparison of variables associated with cerebrospinal fluid neurofilament, total-tau, and neurogranin. Alzheimer's & Dementia : the Journal of the Alzheimer's Association. PMID 31668594 DOI: 10.1016/J.Jalz.2019.07.009  0.31
2019 Yost M, Fiebelkorn CA, Rabinstein AA, Klaas J, Aakre JA, Brown RD, Mielke MM, Knopman DS, Lowe V, Petersen RC, Jack CR, Vemuri P, Graff-Radford J. Incidence of Convexal Subarachnoid Hemorrhage in the Elderly: The Mayo Clinic Study of Aging. Journal of Stroke and Cerebrovascular Diseases : the Official Journal of National Stroke Association. 104451. PMID 31668581 DOI: 10.1016/J.Jstrokecerebrovasdis.2019.104451  0.325
2019 Boeve B, Bove J, Brannelly P, Brushaber D, Coppola G, Dever R, Dheel C, Dickerson B, Dickinson S, Faber K, Fields J, Fong J, Foroud T, Forsberg L, Gavrilova R, ... ... Knopman D, et al. The longitudinal evaluation of familial frontotemporal dementia subjects protocol: Framework and methodology. Alzheimer's & Dementia : the Journal of the Alzheimer's Association. PMID 31636026 DOI: 10.1016/J.Jalz.2019.06.4947  0.3
2019 Johansen MC, Mosley TH, Knopman DS, Wong DF, Wagenknecht LE, Shah AM, Solomon SD, Gottesman RF. Associations Between Left Ventricular Structure, Function, and Cerebral Amyloid: The ARIC-PET Study. Stroke. STROKEAHA119027220. PMID 31597548 DOI: 10.1161/Strokeaha.119.027220  0.369
2019 Power MC, Su D, Wu A, Reid RI, Jack CR, Knopman DS, Coresh J, Huang J, Kantarci K, Sharrett AR, Gottesman RG, Griswold ME, Mosley TH. Association of white matter microstructural integrity with cognition and dementia. Neurobiology of Aging. 83: 63-72. PMID 31585368 DOI: 10.1016/J.Neurobiolaging.2019.08.021  0.433
2019 Bejanin A, Murray ME, Martin P, Botha H, Tosakulwong N, Schwarz CG, Senjem ML, Chételat G, Kantarci K, Jack CR, Boeve BF, Knopman DS, Petersen RC, Giannini C, Parisi JE, et al. Antemortem volume loss mirrors TDP-43 staging in older adults with non-frontotemporal lobar degeneration. Brain : a Journal of Neurology. PMID 31562527 DOI: 10.1093/Brain/Awz277  0.432
2019 Scharf EL, Graff-Radford J, Przybelski SA, Lesnick TG, Mielke MM, Knopman DS, Preboske GM, Schwarz CG, Senjem ML, Gunter JL, Machulda M, Kantarci K, Petersen RC, Jack CR, Vemuri P. Cardiometabolic Health and Longitudinal Progression of White Matter Hyperintensity: The Mayo Clinic Study of Aging. Stroke. STROKEAHA119025822. PMID 31510903 DOI: 10.1161/Strokeaha.119.025822  0.352
2019 Vemuri P, Lesnick TG, Knopman DS, Przybelski SA, Reid RI, Mielke MM, Graff-Radford J, Lowe VJ, Machulda MM, Petersen RC, Jack CR. Amyloid, vascular, and resilience pathways associated with cognitive aging. Annals of Neurology. PMID 31509621 DOI: 10.1002/Ana.25600  0.404
2019 Jack CR, Wiste HJ, Botha H, Weigand SD, Therneau TM, Knopman DS, Graff-Radford J, Jones DT, Ferman TJ, Boeve BF, Kantarci K, Lowe VJ, Vemuri P, Mielke MM, Fields JA, et al. The bivariate distribution of amyloid-β and tau: relationship with established neurocognitive clinical syndromes. Brain : a Journal of Neurology. PMID 31501889 DOI: 10.1093/Brain/Awz268  0.427
2019 Sprung J, Schulte PJ, Knopman DS, Mielke MM, Petersen RC, Weingarten TN, Martin DP, Hanson AC, Schroeder DR, Warner DO. Cognitive function after surgery with regional or general anesthesia: A population-based study. Alzheimer's & Dementia : the Journal of the Alzheimer's Association. PMID 31495602 DOI: 10.1016/J.Jalz.2019.06.4949  0.32
2019 Miyagawa T, Brushaber D, Syrjanen J, Kremers W, Fields J, Forsberg LK, Heuer HW, Knopman D, Kornak J, Boxer A, Rosen H, Boeve B. Use of the CDR® plus NACC FTLD in mild FTLD: Data from the ARTFL/LEFFTDS consortium. Alzheimer's & Dementia : the Journal of the Alzheimer's Association. PMID 31477517 DOI: 10.1016/J.Jalz.2019.05.013  0.35
2019 Zhou X, Wang Y, Sohn S, Therneau TM, Liu H, Knopman DS. Automatic extraction and assessment of lifestyle exposures for Alzheimer's disease using natural language processing. International Journal of Medical Informatics. 130: 103943. PMID 31476655 DOI: 10.1016/J.Ijmedinf.2019.08.003  0.346
2019 Windham BG, Griswold ME, Wilkening SR, Su D, Tingle J, Coker LH, Knopman D, Gottesman RF, Shibata D, Mosley TH. Midlife Smaller and Larger Infarctions, White Matter Hyperintensities, and 20-Year Cognitive Decline: A Cohort Study. Annals of Internal Medicine. PMID 31450238 DOI: 10.7326/M18-0295  0.324
2019 Vassilaki M, Aakre JA, Knopman DS, Kremers WK, Mielke MM, Geda YE, Machulda MM, Al Fakir R, Undavalli C, Roberts RO, Petersen RC. Informant-based hearing difficulties and the risk for mild cognitive impairment and dementia. Age and Ageing. PMID 31437275 DOI: 10.1093/Ageing/Afz099  0.413
2019 Walker KA, Sharrett AR, Wu A, Schneider ALC, Albert M, Lutsey PL, Bandeen-Roche K, Coresh J, Gross AL, Windham BG, Knopman DS, Power MC, Rawlings AM, Mosley TH, Gottesman RF. Association of Midlife to Late-Life Blood Pressure Patterns With Incident Dementia. Jama. 322: 535-545. PMID 31408138 DOI: 10.1001/Jama.2019.10575  0.305
2019 Pokharel Y, Mouhanna F, Schneider ALC, Rawlings AM, Knopman DS, Nambi V, Virani SS, Hoogeveen RC, Alonso A, Heiss G, Coresh J, Mosley T, Gottesman R, Selvin E, Ballantyne C, et al. High-Sensitive Troponin T, Natriuretic Peptide, and Cognitive Change. Journal of the American Geriatrics Society. PMID 31359423 DOI: 10.1111/Jgs.16092  0.335
2019 Jack CR, Therneau TM, Weigand SD, Wiste HJ, Knopman DS, Vemuri P, Lowe VJ, Mielke MM, Roberts RO, Machulda MM, Graff-Radford J, Jones DT, Schwarz CG, Gunter JL, Senjem ML, et al. Prevalence of Biologically vs Clinically Defined Alzheimer Spectrum Entities Using the National Institute on Aging-Alzheimer's Association Research Framework. Jama Neurology. PMID 31305929 DOI: 10.1001/Jamaneurol.2019.1971  0.403
2019 Krell-Roesch J, Syrjanen JA, Vassilaki M, Machulda MM, Mielke MM, Knopman DS, Kremers WK, Petersen RC, Geda YE. Quantity and quality of mental activities and the risk of incident mild cognitive impairment. Neurology. PMID 31292224 DOI: 10.1212/Wnl.0000000000007897  0.362
2019 Rawlings AM, Sharrett AR, Albert MS, Coresh J, Windham BG, Power MC, Knopman DS, Walker K, Burgard S, Mosley TH, Gottesman RF, Selvin E. The Association of Late-Life Diabetes Status and Hyperglycemia With Incident Mild Cognitive Impairment and Dementia: The ARIC Study. Diabetes Care. 42: 1248-1254. PMID 31221696 DOI: 10.2337/Dc19-0120  0.367
2019 Jack CR, Wiste HJ, Therneau TM, Weigand SD, Knopman DS, Mielke MM, Lowe VJ, Vemuri P, Machulda MM, Schwarz CG, Gunter JL, Senjem ML, Graff-Radford J, Jones DT, Roberts RO, et al. Associations of Amyloid, Tau, and Neurodegeneration Biomarker Profiles With Rates of Memory Decline Among Individuals Without Dementia. Jama. 321: 2316-2325. PMID 31211344 DOI: 10.1001/Jama.2019.7437  0.399
2019 Graff-Radford J, Arenaza-Urquijo EM, Knopman DS, Schwarz CG, Brown RD, Rabinstein AA, Gunter JL, Senjem ML, Przybelski SA, Lesnick T, Ward C, Mielke MM, Lowe VJ, Petersen RC, Kremers WK, et al. White matter hyperintensities: relationship to amyloid and tau burden. Brain : a Journal of Neurology. PMID 31199475 DOI: 10.1093/Brain/Awz162  0.385
2019 Tetzloff KA, Duffy JR, Clark HM, Utianski RL, Strand EA, Machulda MM, Botha H, Martin PR, Schwarz CG, Senjem ML, Reid RI, Gunter JL, Spychalla AJ, Knopman DS, Petersen RC, et al. Progressive agrammatic aphasia without apraxia of speech as a distinct syndrome. Brain : a Journal of Neurology. PMID 31199471 DOI: 10.1093/Brain/Awz157  0.308
2019 Mielke MM, Syrjanen JA, Blennow K, Zetterberg H, Vemuri P, Skoog I, Machulda MM, Kremers WK, Knopman DS, Jack C, Petersen RC, Kern S. Plasma and CSF neurofilament light: Relation to longitudinal neuroimaging and cognitive measures. Neurology. PMID 31182505 DOI: 10.1212/Wnl.0000000000007767  0.318
2019 Lowe VJ, Lundt ES, Albertson SM, Przybelski SA, Senjem ML, Parisi JE, Kantarci K, Boeve B, Jones DT, Knopman D, Jack CR, Dickson DW, Petersen RC, Murray ME. Neuroimaging correlates with neuropathologic schemes in neurodegenerative disease. Alzheimer's & Dementia : the Journal of the Alzheimer's Association. PMID 31175025 DOI: 10.1016/J.Jalz.2019.03.016  0.359
2019 Lowe VJ, Bruinsma TJ, Wiste HJ, Min HK, Weigand SD, Fang P, Senjem ML, Therneau TM, Boeve BF, Josephs KA, Pandey MK, Murray ME, Kantarci K, Jones DT, Vemuri P, ... ... Knopman DS, et al. Cross-sectional associations of tau-PET signal with cognition in cognitively unimpaired adults. Neurology. PMID 31147421 DOI: 10.1212/Wnl.0000000000007728  0.378
2019 van der Lee SJ, Conway OJ, Jansen I, Carrasquillo MM, Kleineidam L, van den Akker E, Hernández I, van Eijk KR, Stringa N, Chen JA, Zettergren A, Andlauer TFM, Diez-Fairen M, Simon-Sanchez J, Lleó A, ... ... Knopman D, et al. A nonsynonymous mutation in PLCG2 reduces the risk of Alzheimer's disease, dementia with Lewy bodies and frontotemporal dementia, and increases the likelihood of longevity. Acta Neuropathologica. PMID 31131421 DOI: 10.1007/S00401-019-02026-8  0.38
2019 Machulda MM, Lundt ES, Albertson SM, Kremers WK, Mielke MM, Knopman DS, Bondi MW, Petersen RC. Neuropsychological subtypes of incident mild cognitive impairment in the Mayo Clinic Study of Aging. Alzheimer's & Dementia : the Journal of the Alzheimer's Association. PMID 31128864 DOI: 10.1016/J.Jalz.2019.03.014  0.408
2019 Schulte PJ, Warner DO, Martin DP, Deljou A, Mielke MM, Knopman DS, Petersen RC, Weingarten TN, Warner MA, Rabinstein AA, Hanson AC, Schroeder DR, Sprung J. Association Between Critical Care Admissions and Cognitive Trajectories in Older Adults. Critical Care Medicine. PMID 31107280 DOI: 10.1097/Ccm.0000000000003829  0.342
2019 Wu A, Sharrett AR, Gottesman RF, Power MC, Mosley TH, Jack CR, Knopman DS, Windham BG, Gross AL, Coresh J. Association of Brain Magnetic Resonance Imaging Signs With Cognitive Outcomes in Persons With Nonimpaired Cognition and Mild Cognitive Impairment. Jama Network Open. 2: e193359. PMID 31074810 DOI: 10.1001/jamanetworkopen.2019.3359  0.364
2019 Josephs KA, Murray ME, Tosakulwong N, Weigand SD, Knopman DS, Petersen RC, Jack CR, Whitwell JL, Dickson DW. Brain atrophy in primary age-related tauopathy is linked to transactive response DNA-binding protein of 43 kDa. Alzheimer's & Dementia : the Journal of the Alzheimer's Association. PMID 31056344 DOI: 10.1016/J.Jalz.2019.03.003  0.313
2019 Knopman DS, Petersen RC, Jack CR. A brief history of "Alzheimer disease": Multiple meanings separated by a common name. Neurology. 92: 1053-1059. PMID 31028129 DOI: 10.1212/Wnl.0000000000007583  0.421
2019 Li D, Hagen C, Fett AR, Bui HH, Knopman D, Vemuri P, Machulda MM, Jack CR, Petersen RC, Mielke MM. Longitudinal association between phosphatidylcholines, neuroimaging measures of Alzheimer's disease pathophysiology, and cognition in the Mayo Clinic Study of Aging. Neurobiology of Aging. 79: 43-49. PMID 31026621 DOI: 10.1016/J.Neurobiolaging.2019.03.005  0.416
2019 Zeydan B, Schwarz CG, Lowe VJ, Reid RI, Przybelski SA, Lesnick TG, Kremers WK, Senjem ML, Gunter JL, Min HK, Vemuri P, Knopman DS, Petersen RC, Jack CR, Kantarci OH, et al. Investigation of white matter PiB uptake as a marker of white matter integrity. Annals of Clinical and Translational Neurology. 6: 678-688. PMID 31019992 DOI: 10.1002/Acn3.741  0.319
2019 Sintini I, Martin PR, Graff-Radford J, Senjem ML, Schwarz CG, Machulda MM, Spychalla AJ, Drubach DA, Knopman DS, Petersen RC, Lowe VJ, Jack CR, Josephs KA, Whitwell JL. Longitudinal tau-PET uptake and atrophy in atypical Alzheimer's disease. Neuroimage. Clinical. 23: 101823. PMID 31004914 DOI: 10.1016/J.Nicl.2019.101823  0.383
2019 Li D, Misialek JR, Jack CR, Mielke MM, Knopman D, Gottesman R, Mosley T, Alonso A. Plasma Metabolites Associated with Brain MRI Measures of Neurodegeneration in Older Adults in the Atherosclerosis Risk in Communities⁻Neurocognitive Study (ARIC-NCS). International Journal of Molecular Sciences. 20. PMID 30970556 DOI: 10.3390/Ijms20071744  0.32
2019 Krell-Roesch J, Vassilaki M, Mielke MM, Kremers WK, Lowe VJ, Vemuri P, Machulda MM, Christianson TJ, Syrjanen JA, Stokin GB, Butler LM, Traber M, Jack CR, Knopman DS, Roberts RO, et al. Cortical β-amyloid burden, neuropsychiatric symptoms, and cognitive status: the Mayo Clinic Study of Aging. Translational Psychiatry. 9: 123. PMID 30923322 DOI: 10.1038/S41398-019-0456-Z  0.391
2019 Arenaza-Urquijo EM, Przybelski SA, Lesnick TL, Graff-Radford J, Machulda MM, Knopman DS, Schwarz CG, Lowe VJ, Mielke MM, Petersen RC, Jack CR, Vemuri P. The metabolic brain signature of cognitive resilience in the 80+: beyond Alzheimer pathologies. Brain : a Journal of Neurology. PMID 30851100 DOI: 10.1093/Brain/Awz037  0.457
2019 Wennberg AM, Whitwell JL, Tosakulwong N, Weigand SD, Murray ME, Machulda MM, Petrucelli L, Mielke MM, Jack CR, Knopman DS, Parisi JE, Petersen RC, Dickson DW, Josephs KA. The influence of tau, amyloid, alpha-synuclein, TDP-43, and vascular pathology in clinically normal elderly individuals. Neurobiology of Aging. 77: 26-36. PMID 30776649 DOI: 10.1016/J.Neurobiolaging.2019.01.008  0.425
2019 Rawlings AM, Sharrett AR, Mosley TH, Wong DF, Knopman DS, Gottesman RF. Cognitive Reserve in Midlife is not Associated with Amyloid-β Deposition in Late-Life. Journal of Alzheimer's Disease : Jad. PMID 30775981 DOI: 10.3233/Jad-180785  0.432
2019 Knopman DS, Lundt ES, Therneau TM, Vemuri P, Lowe VJ, Kantarci K, Gunter JL, Senjem ML, Mielke MM, Machulda MM, Boeve BF, Jones DT, Graff-Radford J, Albertson SM, Schwarz CG, et al. Entorhinal cortex tau, amyloid-β, cortical thickness and memory performance in non-demented subjects. Brain : a Journal of Neurology. PMID 30759182 DOI: 10.1093/Brain/Awz025  0.323
2019 Boeve A, Ferman TJ, Aakre J, St Louis E, Silber M, Machulda M, Fields J, Graff-Radford N, Mielke M, Geda Y, Jones D, Graff-Radford J, Knopman D, Petersen R, Boeve B. Excessive Daytime Sleepiness in Major Dementia Syndromes. American Journal of Alzheimer's Disease and Other Dementias. 1533317519828046. PMID 30740984 DOI: 10.1177/1533317519828046  0.42
2019 Staffaroni AM, Ljubenkov PA, Kornak J, Cobigo Y, Datta S, Marx G, Walters SM, Chiang K, Olney N, Elahi FM, Knopman DS, Dickerson BC, Boeve BF, Gorno-Tempini ML, Spina S, et al. Longitudinal multimodal imaging and clinical endpoints for frontotemporal dementia clinical trials. Brain : a Journal of Neurology. 142: 443-459. PMID 30698757 DOI: 10.1093/Brain/Awy319  0.339
2019 West NA, Windham BG, Knopman DS, Shibata DK, Coker LH, Mosley TH. Neuroimaging findings in midlife and risk of late-life dementia over 20 years of follow-up. Neurology. PMID 30659141 DOI: 10.1212/Wnl.0000000000006989  0.348
2019 Palta P, Sharrett AR, Wei J, Meyer ML, Kucharska-Newton A, Power MC, Deal JA, Jack CR, Knopman D, Wright J, Griswold M, Tanaka H, Mosley TH, Heiss G. Central Arterial Stiffness Is Associated With Structural Brain Damage and Poorer Cognitive Performance: The ARIC Study. Journal of the American Heart Association. 8: e011045. PMID 30646799 DOI: 10.1161/Jaha.118.011045  0.359
2019 Whitwell JL, Martin PR, Duffy JR, Clark HM, Machulda MM, Schwarz CG, Weigand SD, Sintini I, Senjem ML, Ertekin-Taner N, Botha H, Utianski RL, Graff-Radford J, Jones DT, Boeve BF, ... Knopman DS, et al. The influence of β-amyloid on [F]AV-1451 in semantic variant of primary progressive aphasia. Neurology. PMID 30635491 DOI: 10.1212/Wnl.0000000000006913  0.322
2019 Knopman DS. Bad news and good news in AD, and how to reconcile them. Nature Reviews Neurology. 15: 61-62. PMID 30622292 DOI: 10.1038/S41582-018-0131-7  0.342
2019 Nedelska Z, Josephs KA, Graff-Radford J, Przybelski SA, Lesnick TG, Boeve BF, Drubach DA, Knopman DS, Petersen RC, Jack CR, Lowe VJ, Whitwell JL, Kantarci K. F-AV-1451 uptake differs between dementia with lewy bodies and posterior cortical atrophy. Movement Disorders : Official Journal of the Movement Disorder Society. PMID 30615804 DOI: 10.1002/Mds.27603  0.358
2019 Krell-Roesch J, Syrjanen JA, Vassilaki M, Trautwein S, Barisch-Fritz B, Boes K, Woll A, Kremers WK, Machulda MM, Mielke MM, Knopman DS, Petersen RC, Geda YE. Physical Exercise, APOE E4 Genotype And Cognitive Trajectories: The Mayo Clinic Study Of Aging Medicine & Science in Sports & Exercise. 51: 473. DOI: 10.1249/01.Mss.0000561924.66614.C4  0.331
2019 Graff-Radford J, de Arenaza-Urquijo E, Schwarz C, Brown RD, Ward CP, Mielke MM, Przybelski S, Rabinstein AA, Lenick TG, Gunter JL, Petersen RC, Kantarci K, Knopman DS, Lowe V, Jack C, et al. Abstract 104: Topographic White Matter Hyperintensity Patterns Associated With Alzheimer Pathologies Stroke. 50. DOI: 10.1161/Str.50.Suppl_1.104  0.344
2019 Scheppach JB, Wu A, Gottesman RF, Knopman DS, Koton S, Mosley TH, Grams ME, Sharrett R, Coresh J. Abstract P019: Albuminuria in Mid-Life and Older-Age and Risk of Dementia: The Atherosclerosis Risk in Communities (ARIC) Study Circulation. 139. DOI: 10.1161/Circ.139.Suppl_1.P019  0.347
2019 Powell D, Kuo P, Deal JA, Gottesman R, Palta P, Knopman D, Gross AL. THE RELATIONSHIP OF APOE ε4 TO THE RELATIVE TIMES AND HAZARDS OF DEMENTIA Innovation in Aging. 3: S587-S587. DOI: 10.1093/Geroni/Igz038.2175  0.413
2019 Corien van Harten A, Wiste HJ, Weigand SD, Mielke MM, Kremers WK, Eichenlaub U, Batrla-Utermann R, Dyer RB, Algeciras-Schimnic A, Knopman DS, Jack CR, Petersen RC. P4-537: DETECTION OF ALZHEIMER'S DISEASE IN CSF USING AUTOMATED ASSAYS FOR CLASSICAL CSF BIOMARKERS Alzheimer's & Dementia. 15: P1521-P1522. DOI: 10.1016/J.Jalz.2019.08.084  0.341
2019 Buciuc M, Botha H, Murray ME, Jones DT, Knopman DS, Petersen RC, Boeve BF, Jack CR, Petrucelli L, Dickson DW, Lowe VJ, Whitwell JL, Josephs KA. DT-02-01: REPURPOSING FDG-PET AS A DIAGNOSTIC TOOL FOR ALZHEIMER'S-RELATED TDP-43-PROTEINOPATHY Alzheimer's & Dementia. 15: P1487-P1488. DOI: 10.1016/J.Jalz.2019.08.010  0.31
2019 Miyagawa T, Przybelski SA, Maltais DD, Min H, Jordan L, Lesnick TG, Graff-Radford J, Jones DT, Savica R, Drubach DA, Knopman DS, Petersen RC, Fields JA, Machulda MM, Forsberg LK, et al. P1-367: Comparison Of Ioflupane-Spect Findings Using Datquant In Patients With Alzheimer'S Disease Dementia And Dementia With Lewy Bodies Alzheimers & Dementia. 15. DOI: 10.1016/J.Jalz.2019.06.922  0.427
2019 Murray A, Burns CM, Vemuri P, Davey C, Tupper D, Lundt ES, Wille SM, Steinert K, Jack CR, Knopman DS. P1-330: THE RELATION BETWEEN MRI FINDINGS AND COGNITIVE IMPAIRMENT IN CHRONIC KIDNEY DISEASE (CKD) PATIENTS AND THE MODIFYING EFFECT OF ALBUMINURIA Alzheimer's & Dementia. 15: P371-P371. DOI: 10.1016/J.Jalz.2019.06.885  0.363
2019 Boeve BF, Ferman TJ, Graff-Radford NR, Knopman DS, Graff-Radford J, Savica R, Jones DT, Drubach DA, Fields JA, Machulda MM, Lucas JA, Forsberg LK, Miyagawa T, Allen LA, Kantarci K, et al. O4-03-03: Clinical Characterization Of Mild Cognitive Impairment Associated With Eventual Lewy Body Disease Pathology Alzheimers & Dementia. 15. DOI: 10.1016/J.Jalz.2019.06.4754  0.414
2019 Vemuri P, Przybelski SA, Lesnick TG, Graff-Radford J, Machulda MM, Reid RI, Mielke MM, Lowe VJ, Reddy AL, Petersen RC, Knopman DS, Jack CR. O3-04-01: BIOMARKERS FOR CAPTURING AMYLOID-INDEPENDENT EFFECTS OF VASCULAR HEALTH ON COGNITIVE DECLINE Alzheimer's & Dementia. 15: P885-P886. DOI: 10.1016/J.Jalz.2019.06.4642  0.355
2019 Ghisays V, Goradia DD, Protas H, Bauer R, Devadas V, Tariot PN, Lowe VJ, Knopman DS, Petersen RC, Jack CR, Caselli RJ, Su Y, Chen K, Reiman EM. O3-02-02: AMYLOID PET, TAU PET, AND MRI MEASUREMENTS IN COGNITIVELY UNIMPAIRED PERSONS WITH TWO, ONE, AND NO COPIES OF THE APOE4 ALLELE Alzheimer's & Dementia. 15: P878-P878. DOI: 10.1016/J.Jalz.2019.06.4631  0.367
2019 Krell-Roesch J, Syrjanen J, Harten ACv, Vassilaki M, Mielke MM, Vemuri P, Machulda MM, Lowe VJ, Jack CR, Kremers WK, Knopman DS, Stokin GB, Petersen RC, Geda YE. O2-11-01: Cross-Sectional Associations Between Csf Biomarkers Of Amyloid And Tau With Neuropsychiatric Symptoms: The Mayo Clinic Study Of Aging Alzheimers & Dementia. 15. DOI: 10.1016/J.Jalz.2019.06.4511  0.314
2019 Li D, Hagen CE, Bui HH, Vemuri P, Knopman DS, Jack CR, Petersen RC, Mielke MM. O2-05-05: CORRELATION OF CSF PHOSPHOLIPIDS AND ALZHEIMER'S DISEASE NEUROPATHOLOGY IN THE MAYO CLINIC STUDY OF AGING Alzheimer's & Dementia. 15: P547-P547. DOI: 10.1016/J.Jalz.2019.06.4479  0.367
2019 Jack CR, Therneau TM, Weigand SD, Wiste HJ, Knopman DS, Vemuri P, Lowe VJ, Mielke MM, Roberts RO, Machulda MM, Graff-Radford J, Jones DT, Schwarz CG, Gunter JL, Senjem ML, et al. O2-03-05: Prevalence Of Clinically Versus Biologically Defined Alzheimer'S Spectrum Entities Using The National Institute On Aging - Alzheimer'S Association Research Framework Alzheimers & Dementia. 15. DOI: 10.1016/J.Jalz.2019.06.4467  0.36
2019 Arenaza-Urquijo EM, Przybelski SA, Machulda MM, Knopman DS, Lowe VJ, Mielke MM, Reddy AL, Geda YE, Jack CR, Petersen RC, Vemuri P. IC-P-160: STRESS: BETTER COPING ASSOCIATED WITH LOWER TAU IN PRECLINICAL ALZHEIMER'S DISEASE Alzheimer's & Dementia. 15: P128-P128. DOI: 10.1016/J.Jalz.2019.06.4275  0.344
2019 Jones DT, Lowe VJ, Graff-Radford J, Botha H, Murray ME, Senjem ML, Gunter JL, Wiste HJ, Boeve BF, Knopman DS, Petersen RC, Jack CR. Ic-P-027: Decoding Glucose Metabolism In Alzheimer'S Disease Reveals Macro-Scale Brain Organization Related To Disease Expression Alzheimers & Dementia. 15. DOI: 10.1016/J.Jalz.2019.06.4189  0.315
2019 Botha H, Graff-Radford J, Gunter JL, Lowe VJ, Przybelski SA, Schwarz CG, Senjem ML, Kantarci K, Boeve B, Vemuri P, Knopman DS, Petersen RC, Jack CR, Jones DT. Ic-P-022: Brain States And Tau Pet Patterns Interact Across The Aging-Alzheimer'S Continuum Alzheimers & Dementia. 15. DOI: 10.1016/J.Jalz.2019.06.4184  0.331
2019 Nedelska Z, Miyagawa T, Przybelski SA, Maltais DD, Min P, Jordan L, Lesnick TG, Graff-Radford J, Jones DT, Savica R, Drubach DA, Knopman DS, Petersen RC, Fields JA, Machulda MM, et al. Ic-P-064: Analysis Of Ioflupane-Spect Findings Using Datquant In Patients With Mild Cognitive Impairment Alzheimers & Dementia. 15. DOI: 10.1016/J.Jalz.2019.06.3936  0.369
2019 Arenaza-Urquijo EM, Przybelski SA, Machulda MM, Knopman DS, Lowe VJ, Mielke MM, Reddy AL, Geda YE, Jack CR, Petersen RC, Vemuri P. P4-249: STRESS COPING ABILITY ASSOCIATED WITH TAU IN PRECLINICAL ALZHEIMER'S DISEASE Alzheimer's & Dementia. 15: P1374-P1375. DOI: 10.1016/J.Jalz.2019.06.3912  0.363
2019 Machulda MM, Lundt ES, Albertson SM, Spychalla AJ, Mielke MM, Jack CR, Kremers WK, Vemuri P, Knopman DS, Bondi MW, Petersen RC. Ic-P-086: Cortical Atrophy Patterns Of Empirically Derived Incident Mci Subtypes In The Mayo Clinic Study Of Aging Alzheimers & Dementia. 15. DOI: 10.1016/J.Jalz.2019.06.3496  0.309
2019 Nedelska Z, Boeve B, Ferman TJ, Senjem ML, Przybelski SA, Lesnick TG, Knopman DS, Graff-Radford J, Jones DT, Savica R, Drubach DA, Fields JA, Graff-Radford NR, Lowe VJ, Jack CR, et al. Ic-02-03: Mild Cognitive Impairment Progressing To Dementia With Lewy Bodies: Regional Atrophy Rates And Relationship To Av-1451 Uptake Alzheimers & Dementia. 15. DOI: 10.1016/J.Jalz.2019.06.3461  0.399
2019 Dutt T, Vassilaki M, Christianson TJ, Knopman DS, Kremers WK, Mielke MM, Machulda MM, Geda YE, Undavalli C, Roberts RO, Petersen RC. P3-278: Chronic Kidney Disease And Risk Of Mild Cognitive Impairment Alzheimers & Dementia. 15. DOI: 10.1016/J.Jalz.2019.06.3309  0.376
2019 Walker KA, Zhou Y, Hughes TM, Jack CR, Knopman DS, Sharrett R, Wong DF, Mosley TH, Gottesman RF. P2-342: The Effect Of Race On The Association Between White Matter Structure And Brain Amyloid Deposition: The Aric-Pet Study Alzheimers & Dementia. 15. DOI: 10.1016/J.Jalz.2019.06.2749  0.303
2018 Jones DT, Townley RA, Graff-Radford J, Botha H, Knopman DS, Petersen RC, Jack CR, Lowe VJ, Boeve BF. Amyloid- and tau-PET imaging in a familial prion kindred. Neurology. Genetics. 4: e290. PMID 30584595 DOI: 10.1212/Nxg.0000000000000290  0.337
2018 Petersen RC, Lundt ES, Therneau TM, Weigand SD, Knopman DS, Mielke MM, Roberts RO, Lowe VJ, Machulda MM, Kremers WK, Geda YE, Jack CR. Predicting Progression to Mild Cognitive Impairment. Annals of Neurology. PMID 30521086 DOI: 10.1002/Ana.25388  0.427
2018 Battle MR, Pillay LC, Lowe VJ, Knopman D, Kemp B, Rowe CC, Doré V, Villemagne VL, Buckley CJ. Centiloid scaling for quantification of brain amyloid with [F]flutemetamol using multiple processing methods. Ejnmmi Research. 8: 107. PMID 30519791 DOI: 10.1186/S13550-018-0456-7  0.306
2018 Vassilaki M, Aakre JA, Kremers WK, Mielke MM, Geda YE, Machulda MM, Knopman DS, Coloma PM, Schauble B, Vemuri P, Lowe VJ, Jack CR, Petersen RC, Roberts RO. Association Between Functional Performance and Alzheimer's Disease Biomarkers in Individuals Without Dementia. Journal of the American Geriatrics Society. PMID 30462843 DOI: 10.1111/Jgs.15577  0.466
2018 Deal JA, Sharrett AR, Albert M, Bandeen-Roche K, Burgard S, Thomas SD, Gottesman RF, Knopman D, Mosley T, Klein B, Klein R. Retinal signs and risk of incident dementia in the Atherosclerosis Risk in Communities study. Alzheimer's & Dementia : the Journal of the Alzheimer's Association. PMID 30439332 DOI: 10.1016/J.Jalz.2018.10.002  0.321
2018 Lutsey PL, Chen N, Mirabelli MC, Lakshminarayan K, Knopman DS, Vossel KA, Gottesman RF, Mosley TH, Alonso A. Impaired Lung Function, Lung Disease and Risk of Incident Dementia. American Journal of Respiratory and Critical Care Medicine. PMID 30433810 DOI: 10.1164/Rccm.201807-1220Oc  0.342
2018 Wennberg AM, Tosakulwong N, Lesnick TG, Murray ME, Whitwell JL, Liesinger AM, Petrucelli L, Boeve BF, Parisi JE, Knopman DS, Petersen RC, Dickson DW, Josephs KA. Association of Apolipoprotein E ε4 With Transactive Response DNA-Binding Protein 43. Jama Neurology. 75: 1347-1354. PMID 30422173 DOI: 10.1001/Jamaneurol.2018.3139  0.374
2018 Kern S, Syrjanen JA, Blennow K, Zetterberg H, Skoog I, Waern M, Hagen CE, van Harten AC, Knopman DS, Jack CR, Petersen RC, Mielke MM. Association of Cerebrospinal Fluid Neurofilament Light Protein With Risk of Mild Cognitive Impairment Among Individuals Without Cognitive Impairment. Jama Neurology. PMID 30419087 DOI: 10.1001/Jamaneurol.2018.3459  0.41
2018 Stricker NH, Lundt ES, Edwards KK, Machulda MM, Kremers WK, Roberts RO, Knopman DS, Petersen RC, Mielke MM. Comparison of PC and iPad administrations of the Cogstate Brief Battery in the Mayo Clinic Study of Aging: assessing cross-modality equivalence of computerized neuropsychological tests. The Clinical Neuropsychologist. 1-25. PMID 30417735 DOI: 10.1080/13854046.2018.1519085  0.33
2018 Walker KA, Windham BG, Brown CH, Knopman DS, Jack CR, Mosley TH, Selvin E, Wong DF, Hughes TM, Zhou Y, Gross AL, Gottesman RF. The Association of Mid- and Late-Life Systemic Inflammation with Brain Amyloid Deposition: The ARIC-PET Study. Journal of Alzheimer's Disease : Jad. PMID 30400093 DOI: 10.3233/Jad-180469  0.318
2018 Ljubenkov PA, Staffaroni AM, Rojas JC, Allen IE, Wang P, Heuer H, Karydas A, Kornak J, Cobigo Y, Seeley WW, Grinberg LT, Spina S, Fagan AM, Jerome G, Knopman D, et al. Cerebrospinal fluid biomarkers predict frontotemporal dementia trajectory. Annals of Clinical and Translational Neurology. 5: 1250-1263. PMID 30349860 DOI: 10.1002/Acn3.643  0.332
2018 Evered L, Silbert B, Knopman DS, Scott DA, DeKosky ST, Rasmussen LS, Oh ES, Crosby G, Berger M, Eckenhoff RG. Recommendations for the Nomenclature of Cognitive Change Associated with Anaesthesia and Surgery-20181. Journal of Alzheimer's Disease : Jad. 66: 1-10. PMID 30347621 DOI: 10.3233/Jad-189004  0.371
2018 Evered L, Silbert B, Knopman DS, Scott DA, DeKosky ST, Rasmussen LS, Oh ES, Crosby G, Berger M, Eckenhoff RG. Recommendations for the nomenclature of cognitive change associated with anaesthesia and surgery-2018. British Journal of Anaesthesia. 121: 1005-1012. PMID 30336844 DOI: 10.1016/J.Bja.2017.11.087  0.371
2018 Evered L, Silbert B, Knopman DS, Scott DA, DeKosky ST, Rasmussen LS, Oh ES, Crosby G, Berger M, Eckenhoff RG. Recommendations for the Nomenclature of Cognitive Change Associated with Anaesthesia and Surgery-2018. Anesthesiology. 129: 872-879. PMID 30325806 DOI: 10.1097/Aln.0000000000002334  0.371
2018 Evered L, Silbert B, Knopman DS, Scott DA, DeKosky ST, Rasmussen LS, Oh ES, Crosby G, Berger M, Eckenhoff RG. Recommendations for the Nomenclature of Cognitive Change Associated With Anaesthesia and Surgery-2018. Anesthesia and Analgesia. PMID 30325748 DOI: 10.1213/Ane.0000000000003634  0.371
2018 Evered L, Silbert B, Knopman DS, Scott DA, DeKosky ST, Rasmussen LS, Oh ES, Crosby G, Berger M, Eckenhoff RG. Recommendations for the nomenclature of cognitive change associated with anaesthesia and surgery-2018. Acta Anaesthesiologica Scandinavica. 62: 1473-1480. PMID 30325016 DOI: 10.1111/Aas.13250  0.371
2018 Evered L, Silbert B, Knopman DS, Scott DA, DeKosky ST, Rasmussen LS, Oh ES, Crosby G, Berger M, Eckenhoff RG. Recommendations for the nomenclature of cognitive change associated with anaesthesia and surgery-2018. Canadian Journal of Anaesthesia = Journal Canadien D'Anesthesie. PMID 30324338 DOI: 10.1007/S12630-018-1216-X  0.371
2018 Palta P, Sharrett AR, Deal JA, Evenson KR, Gabriel KP, Folsom AR, Gross AL, Windham BG, Knopman D, Mosley TH, Heiss G. Leisure-time physical activity sustained since midlife and preservation of cognitive function: The Atherosclerosis Risk in Communities study cohort. Alzheimer's & Dementia : the Journal of the Alzheimer's Association. PMID 30321503 DOI: 10.1016/J.Jalz.2018.08.008  0.369
2018 Vemuri P, Lesnick TG, Przybelski SA, Graff-Radford J, Reid RI, Lowe VJ, Zuk SM, Senjem ML, Schwarz CG, Gunter JL, Kantarci K, Machulda MM, Mielke MM, Petersen RC, Knopman DS, et al. Development of a cerebrovascular MRI biomarker for cognitive aging. Annals of Neurology. PMID 30264411 DOI: 10.1002/Ana.25346  0.348
2018 Knopman DS. The Telephone Interview for Cognitive Status Cognitive and Behavioral Neurology. 31: 158. PMID 30239467 DOI: 10.1097/Wnn.0000000000000166  0.365
2018 Ramanan VK, Przybelski SA, Graff-Radford J, Castillo AM, Lowe VJ, Mielke MM, Roberts RO, Reid RI, Knopman DS, Jack CR, Petersen RC, Vemuri P. Statins and Brain Health: Alzheimer's Disease and Cerebrovascular Disease Biomarkers in Older Adults. Journal of Alzheimer's Disease : Jad. PMID 30149450 DOI: 10.3233/Jad-180446  0.374
2018 Dickson DW, Heckman MG, Murray ME, Soto AI, Walton RL, Diehl NN, van Gerpen JA, Uitti RJ, Wszolek ZK, Ertekin-Taner N, Knopman DS, Petersen RC, Graff-Radford NR, Boeve BF, Bu G, et al. ε4 is associated with severity of Lewy body pathology independent of Alzheimer pathology. Neurology. PMID 30143564 DOI: 10.1212/Wnl.0000000000006212  0.401
2018 Vassilaki M, Aakre JA, Kremers WK, Mielke MM, Geda YE, Alhurani RE, Dutt T, Machulda MM, Knopman DS, Vemuri P, Coloma PM, Schauble B, Lowe VJ, Jack CR, Petersen RC, et al. The Association of Multimorbidity With Preclinical AD Stages and SNAP in Cognitively Unimpaired Persons. The Journals of Gerontology. Series a, Biological Sciences and Medical Sciences. PMID 30124772 DOI: 10.1093/Gerona/Gly149  0.453
2018 Krell-Roesch J, Cerhan LP, Machulda MM, Roberts RO, Mielke MM, Knopman DS, Syrjanen JA, Christianson TJ, Petersen RC, Geda YE. Functional Activity and Neuropsychiatric Symptoms in Normal Aging and Mild Cognitive Impairment: The Mayo Clinic Study of Aging. Alzheimer Disease and Associated Disorders. PMID 30106755 DOI: 10.1097/Wad.0000000000000266  0.363
2018 Schneider ALC, Zhao D, Lutsey PL, Gottesman RF, Sharrett AR, Rawlings AM, Alonso A, Knopman D, Mosley TH, Selvin E, Michos ED. Serum Vitamin D Concentrations and Cognitive Change Over 20 Years: The Atherosclerosis Risk in Communities Neurocognitive Study. Neuroepidemiology. 51: 131-137. PMID 30092587 DOI: 10.1159/000490912  0.343
2018 Schulte PJ, Roberts RO, Knopman DS, Petersen RC, Hanson AC, Schroeder DR, Weingarten TN, Martin DP, Warner DO, Sprung J. Association between exposure to anaesthesia and surgery and long-term cognitive trajectories in older adults: report from the Mayo Clinic Study of Aging. British Journal of Anaesthesia. 121: 398-405. PMID 30032878 DOI: 10.1016/J.Bja.2018.05.060  0.336
2018 Sahoo A, Benjanin A, Murray ME, Tosakulwong N, Weigand SD, Serie AM, Senjem ML, Machulda MM, Parisi JE, Boeve BF, Knopman DS, Petersen RC, Dickson DW, Whitwell JL, Josephs KA. TDP-43 and Alzheimer's Disease Pathologic Subtype in Non-Amnestic Alzheimer's Disease Dementia. Journal of Alzheimer's Disease : Jad. PMID 30010126 DOI: 10.3233/Jad-180169  0.423
2018 Nedelska Z, Senjem ML, Przybelski SA, Lesnick TG, Lowe VJ, Boeve BF, Arani A, Vemuri P, Graff-Radford J, Ferman TJ, Jones DT, Savica R, Knopman DS, Petersen RC, Jack CR, et al. Regional cortical perfusion on arterial spin labeling MRI in dementia with Lewy bodies: Associations with clinical severity, glucose metabolism and tau PET. Neuroimage. Clinical. 19: 939-947. PMID 30003031 DOI: 10.1016/J.Nicl.2018.06.020  0.349
2018 van Harten AC, Mielke MM, Swenson-Dravis DM, Hagen CE, Edwards KK, Roberts RO, Geda YE, Knopman DS, Petersen RC. Subjective cognitive decline and risk of MCI: The Mayo Clinic Study of Aging. Neurology. PMID 29959257 DOI: 10.1212/Wnl.0000000000005863  0.41
2018 Weintraub S, Carrillo MC, Farias ST, Goldberg TE, Hendrix JA, Jaeger J, Knopman DS, Langbaum JB, Park DC, Ropacki MT, Sikkes SAM, Welsh-Bohmer KA, Bain LJ, Brashear R, Budur K, et al. Measuring cognition and function in the preclinical stage of Alzheimer's disease. Alzheimer's & Dementia (New York, N. Y.). 4: 64-75. PMID 29955653 DOI: 10.1016/J.Trci.2018.01.003  0.416
2018 Utianski RL, Whitwell JL, Schwarz CG, Duffy JR, Botha H, Clark HM, Machulda MM, Senjem ML, Knopman DS, Petersen RC, Jack CR, Lowe VJ, Josephs KA. Tau Uptake in Agrammatic Primary Progressive Aphasia with and without Apraxia of Speech. European Journal of Neurology. PMID 29935044 DOI: 10.1111/Ene.13733  0.304
2018 Vassilaki M, Aakre JA, Syrjanen JA, Mielke MM, Geda YE, Kremers WK, Machulda MM, Alhurani RE, Staubo SC, Knopman DS, Petersen RC, Lowe VJ, Jack CR, Roberts RO. Mediterranean Diet, Its Components, and Amyloid Imaging Biomarkers. Journal of Alzheimer's Disease : Jad. 64: 281-290. PMID 29889074 DOI: 10.3233/Jad-171121  0.366
2018 Wennberg AMV, Hagen CE, Edwards K, Roberts RO, Machulda MM, Knopman DS, Petersen RC, Mielke MM. Association of antidiabetic medication use, cognitive decline, and risk of cognitive impairment in older people with type 2 diabetes: Results from the population-based Mayo Clinic Study of Aging. International Journal of Geriatric Psychiatry. PMID 29873112 DOI: 10.1002/Gps.4900  0.342
2018 Davies G, Lam M, Harris SE, Trampush JW, Luciano M, Hill WD, Hagenaars SP, Ritchie SJ, Marioni RE, Fawns-Ritchie C, Liewald DCM, Okely JA, Ahola-Olli AV, Barnes CLK, Bertram L, ... ... Knopman DS, et al. Study of 300,486 individuals identifies 148 independent genetic loci influencing general cognitive function. Nature Communications. 9: 2098. PMID 29844566 DOI: 10.1038/S41467-018-04362-X  0.369
2018 Lowe VJ, Bruinsma TJ, Min HK, Lundt ES, Fang P, Senjem ML, Boeve BF, Josephs KA, Pandey MK, Murray ME, Kantarci K, Jones DT, Schwarz CG, Knopman DS, Petersen RC, et al. Elevated medial temporal lobe and pervasive brain tau-PET signal in normal participants. Alzheimer's & Dementia (Amsterdam, Netherlands). 10: 210-216. PMID 29780865 DOI: 10.1016/J.Dadm.2018.01.005  0.399
2018 Knopman DS, Gottesman RF, Sharrett AR, Tapia AL, DavisThomas S, Windham BG, Coker L, Schneider ALC, Alonso A, Coresh J, Albert MS, Mosley TH. Midlife vascular risk factors and midlife cognitive status in relation to prevalence of mild cognitive impairment and dementia in later life: The Atherosclerosis Risk in Communities Study. Alzheimer's & Dementia : the Journal of the Alzheimer's Association. PMID 29763593 DOI: 10.1016/J.Jalz.2018.03.011  0.407
2018 Roberts RO, Aakre JA, Kremers WK, Vassilaki M, Knopman DS, Mielke MM, Alhurani R, Geda YE, Machulda MM, Coloma P, Schauble B, Lowe VJ, Jack CR, Petersen RC. Prevalence and Outcomes of Amyloid Positivity Among Persons Without Dementia in a Longitudinal, Population-Based Setting. Jama Neurology. PMID 29710225 DOI: 10.1001/Jamaneurol.2018.0629  0.364
2018 Lowe VJ, Lundt ES, Senjem ML, Schwarz CG, Min HK, Przybelski SA, Kantarci K, Knopman D, Petersen RC, Jack CR. White matter reference region in PET studies of C-Pittsburgh Compound B uptake: effects of age and amyloid-β deposition. Journal of Nuclear Medicine : Official Publication, Society of Nuclear Medicine. PMID 29674420 DOI: 10.2967/Jnumed.117.204271  0.397
2018 Knopman DS, Haeberlein SB, Carrillo MC, Hendrix JA, Kerchner G, Margolin R, Maruff P, Miller DS, Tong G, Tome MB, Murray ME, Nelson PT, Sano M, Mattsson N, Sultzer DL, et al. The National Institute on Aging and the Alzheimer's Association Research Framework for Alzheimer's disease: Perspectives from the Research Roundtable. Alzheimer's & Dementia : the Journal of the Alzheimer's Association. 14: 563-575. PMID 29653607 DOI: 10.1016/J.Jalz.2018.03.002  0.35
2018 Mielke MM, Hagen CE, Xu J, Chai X, Vemuri P, Lowe VJ, Airey DC, Knopman DS, Roberts RO, Machulda MM, Jack CR, Petersen RC, Dage JL. Plasma phospho-tau181 increases with Alzheimer's disease clinical severity and is associated with tau- and amyloid-positron emission tomography. Alzheimer's & Dementia : the Journal of the Alzheimer's Association. PMID 29626426 DOI: 10.1016/J.Jalz.2018.02.013  0.379
2018 Krell-Roesch J, Feder NT, Roberts RO, Mielke MM, Christianson TJ, Knopman DS, Petersen RC, Geda YE. Leisure-Time Physical Activity and the Risk of Incident Dementia: The Mayo Clinic Study of Aging. Journal of Alzheimer's Disease : Jad. PMID 29614667 DOI: 10.3233/Jad-171141  0.369
2018 Palta P, Chen H, Deal JA, Sharrett AR, Gross A, Knopman D, Griswold M, Heiss G, Mosley TH. Olfactory function and neurocognitive outcomes in old age: The Atherosclerosis Risk in Communities Neurocognitive Study. Alzheimer's & Dementia : the Journal of the Alzheimer's Association. PMID 29605223 DOI: 10.1016/J.Jalz.2018.02.019  0.383
2018 Whitwell JL, Graff-Radford J, Tosakulwong N, Weigand SD, Machulda M, Senjem ML, Spychalla AJ, Vemuri P, Jones DT, Drubach DA, Knopman DS, Boeve BF, Ertekin-Taner N, Petersen RC, Lowe VJ, et al. Imaging correlations of tau, amyloid, metabolism, and atrophy in typical and atypical Alzheimer's disease. Alzheimer's & Dementia : the Journal of the Alzheimer's Association. PMID 29605222 DOI: 10.1016/J.Jalz.2018.02.020  0.375
2018 Jung Y, Jordan LG, Lowe VJ, Kantarci K, Parisi JE, Dickson DW, Murray ME, Reichard RR, Ferman TJ, Jones DT, Graff-Radford J, Savica R, Machulda MM, Fields JA, Allen LA, ... ... Knopman DS, et al. Clinicopathological andI-FP-CIT SPECT correlations in patients with dementia. Annals of Clinical and Translational Neurology. 5: 376-381. PMID 29560382 DOI: 10.1002/Acn3.521  0.365
2018 Hughes TM, Wagenknecht LE, Craft S, Mintz A, Heiss G, Palta P, Wong D, Zhou Y, Knopman D, Mosley TH, Gottesman RF. Arterial stiffness and dementia pathology: Atherosclerosis Risk in Communities (ARIC)-PET Study. Neurology. PMID 29549223 DOI: 10.1212/Wnl.0000000000005259  0.301
2018 Wennberg AMV, Hagen CE, Machulda MM, Hollman JH, Roberts RO, Knopman DS, Petersen RC, Mielke MM. The association between peripheral total IGF-1, IGFBP-3, and IGF-1/IGFBP-3 and functional and cognitive outcomes in the Mayo Clinic Study of Aging. Neurobiology of Aging. 66: 68-74. PMID 29547749 DOI: 10.1016/J.Neurobiolaging.2017.11.017  0.364
2018 Botha H, Mantyh WG, Murray ME, Knopman DS, Przybelski SA, Wiste HJ, Graff-Radford J, Josephs KA, Schwarz CG, Kremers WK, Boeve BF, Petersen RC, Machulda MM, Parisi JE, Dickson DW, et al. FDG-PET in tau-negative amnestic dementia resembles that of autopsy-proven hippocampal sclerosis. Brain : a Journal of Neurology. PMID 29538658 DOI: 10.1093/Brain/Awy049  0.409
2018 Jack CR, Wiste HJ, Schwarz CG, Lowe VJ, Senjem ML, Vemuri P, Weigand SD, Therneau TM, Knopman DS, Gunter JL, Jones DT, Graff-Radford J, Kantarci K, Roberts RO, Mielke MM, et al. Longitudinal tau PET in ageing and Alzheimer's disease. Brain : a Journal of Neurology. PMID 29538647 DOI: 10.1093/Brain/Awy059  0.451
2018 Carvalho DZ, St Louis EK, Knopman DS, Boeve BF, Lowe VJ, Roberts RO, Mielke MM, Przybelski SA, Machulda MM, Petersen RC, Jack CR, Vemuri P. Association of Excessive Daytime Sleepiness With Longitudinal β-Amyloid Accumulation in Elderly Persons Without Dementia. Jama Neurology. PMID 29532057 DOI: 10.1001/Jamaneurol.2018.0049  0.44
2018 Pakhomov SVS, Eberly LE, Knopman DS. Recurrent perseverations on semantic verbal fluency tasks as an early marker of cognitive impairment. Journal of Clinical and Experimental Neuropsychology. 1-9. PMID 29502483 DOI: 10.1080/13803395.2018.1438372  0.35
2018 Deal JA, Sharrett AR, Rawlings AM, Gottesman RF, Bandeen-Roche K, Albert M, Knopman D, Selvin E, Wasserman BA, Klein B, Klein R. Retinal signs and 20-year cognitive decline in the Atherosclerosis Risk in Communities Study. Neurology. PMID 29490915 DOI: 10.1212/Wnl.0000000000005205  0.345
2018 Knopman DS, Lundt ES, Therneau TM, Vemuri P, Lowe VJ, Kantarci K, Gunter JL, Senjem ML, Mielke MM, Machulda MM, Roberts RO, Boeve BF, Jones DT, Petersen RC, Jack CR. Joint associations of β-amyloidosis and cortical thickness with cognition. Neurobiology of Aging. 65: 121-131. PMID 29471214 DOI: 10.1016/J.Neurobiolaging.2018.01.017  0.424
2018 Botha H, Mantyh WG, Graff-Radford J, Machulda MM, Przybelski SA, Wiste HJ, Senjem ML, Parisi JE, Petersen RC, Murray ME, Boeve BF, Lowe VJ, Knopman DS, Jack CR, Jones DT. Tau-negative amnestic dementia masquerading as Alzheimer disease dementia. Neurology. PMID 29438037 DOI: 10.1212/Wnl.0000000000005124  0.427
2018 Knopman DS. Sifting through a failed Alzheimer trial: What biomarkers tell us about what happened. Neurology. 90: 447-448. PMID 29429973 DOI: 10.1212/Wnl.0000000000005073  0.381
2018 Knopman DS, Siemers ER, Bain LJ, Hendrix JA, Carrillo MC. National Institute on Aging - Alzheimer's Association Research Framework lays the groundwork for deeper understanding of Alzheimer's disease. Alzheimer's & Dementia : the Journal of the Alzheimer's Association. 14: 261-262. PMID 29413643 DOI: 10.1016/J.Jalz.2018.01.001  0.373
2018 Fatemi F, Kantarci K, Graff-Radford J, Preboske GM, Weigand SD, Przybelski SA, Knopman DS, Machulda MM, Roberts RO, Mielke MM, Petersen RC, Jack CR, Vemuri P. Sex differences in cerebrovascular pathologies on FLAIR in cognitively unimpaired elderly. Neurology. PMID 29343465 DOI: 10.1212/Wnl.0000000000004913  0.378
2018 Whitwell JL, Graff-Radford J, Tosakulwong N, Weigand SD, Machulda M, Senjem ML, Schwarz CG, Spychalla AJ, Jones DT, Drubach DA, Knopman DS, Boeve BF, Ertekin-Taner N, Petersen RC, Lowe VJ, et al. [18 F]AV-1451 clustering of entorhinal and cortical uptake in Alzheimer's disease. Annals of Neurology. PMID 29323751 DOI: 10.1002/Ana.25142  0.359
2018 Gottesman RF, Dearborn J, Hao Q, Knopman DS, Mosley TH, Qiao Y, Wagenknecht LE, Wong DF, Zhou Y, Wasserman BA. Abstract 151: Intracranial Atherosclerotic Disease and Brain Amyloid Deposition: The ARIC Study Stroke. 49. DOI: 10.1161/Str.49.Suppl_1.151  0.358
2018 Wadley V, Howard V, Knopman D, Lal B, Meschia J, Howard G, Brott T, Lazar R. CENTRALIZED COGNITIVE ASSESSMENT IN A MULTICENTER TRIAL OF TREATMENT MODES FOR ASYMPTOMATIC CAROTID ARTERY DISEASE Innovation in Aging. 2: 702-702. DOI: 10.1093/Geroni/Igy023.2607  0.323
2018 Atri A, Knopman DS, Norman M, Karlawish J, Sano M, Onyike CU, Lin P, Clevenger C, Scanland S, Hendrix J, Carrillo MC, Dickerson BC. P4-288: Details Of The New Alzheimer'S Association Best Clinical Practice Guidelines For The Evaluation Of Neurodegenerative Cognitive Behavioral Syndromes, Alzheimer'S Disease And Dementias In The United States Alzheimers & Dementia. 14. DOI: 10.1016/J.Jalz.2018.07.110  0.438
2018 Gunter JL, Spychalla AJ, Ward CP, Graff-Radford J, Huston J, Kantarci K, Knopman DS, Petersen RC, Jack CR. P4-232: Automating Cerebral Microbleed Detection In Support Of Alzheimer'S Disease Trials Using A Convolutional Neural Network Ai Alzheimers & Dementia. 14. DOI: 10.1016/J.Jalz.2018.07.053  0.317
2018 Murray A, Burns CM, Slinin Y, Tupper D, Davey C, Knopman DS. P2-280: Metabolic Factors Associated With Moderate To Severe Cognitive Impairment In Chronic Kidney Disease Alzheimers & Dementia. 14. DOI: 10.1016/J.Jalz.2018.06.969  0.367
2018 Chen Q, Boeve BF, Tosakulwong N, Lesnick TG, Brushaber D, Dheel C, Fields JA, Forsberg LK, Gavrilova RH, Gearhart D, Haley D, Gunter JL, Graff-Radford J, Jones DT, Knopman DS, et al. P1-420: Accelerated Neurochemical Changes Prior To Phenoconversion To Frontotemporal Lobar Degeneration In Presymptomatic Microtubule-Associated Protein Tau (Mapt) Mutation Carriers: A Longitudinal Mrs Study Alzheimers & Dementia. 14. DOI: 10.1016/J.Jalz.2018.06.429  0.304
2018 Kornak J, Fields JA, Farmer S, Boeve BF, Rosen HJ, Boxer AL, Bove J, Brushaber D, Coppola G, Dheel C, Dickerson BC, Dickinson S, Faber K, Fong J, Foroud TM, ... ... Knopman DS, et al. P1-281: Nonlinear N-Score Estimation For Establishing Cognitive Norms From The National Alzheimer'S Coordinating Center (Nacc) Dataset Alzheimers & Dementia. 14. DOI: 10.1016/J.Jalz.2018.06.287  0.365
2018 Staffaroni AM, Bajorek L, Ljubenkov P, Casaletto K, Elahi F, Rascovsky K, Boeve BF, Boxer AL, Bove J, Brushaber D, Coppola G, Dheel C, Dickerson BC, Fields JA, Fong J, ... ... Knopman DS, et al. O1-08-01: The Nih-Examiner Is Sensitive To Cognitive Changes In Asymptomatic And Mildly Symptomatic Familial Frontotemporal Dementia Alzheimers & Dementia. 14. DOI: 10.1016/J.Jalz.2018.06.2372  0.379
2018 Botha H, Graff-Radford J, Lowe VJ, Przybelski SA, Wiste HJ, Gunter JL, Senjem ML, Kantarci K, Boeve BF, Knopman DS, Petersen RC, Jack CR, Jones DT. Ic-P-028: Variability In Pdmn Connectivity And Relative Hubness In Cognitively Normal Individuals Predict Amyloid And Tau Deposition Patterns In Typical Alzheimer'S Disease Alzheimers & Dementia. 14. DOI: 10.1016/J.Jalz.2018.06.2092  0.414
2018 Nedelska Z, Schwarz CG, Lesnick TG, Przybelski SA, Boeve BF, Lowe VJ, Kremers WK, Gunter JL, Senjem ML, Graff-Radford J, Ferman TJ, Knopman DS, Petersen RC, Jack CR, Kantarci K. IC-P-019: LONGITUDINAL ACCUMULATION OF β-AMYLOID ON PET IN DEMENTIA WITH LEWY BODIES AND RELATIONSHIP TO CLINICAL DISEASE PROGRESSION Alzheimers & Dementia. 14. DOI: 10.1016/J.Jalz.2018.06.1787  0.372
2018 Li D, Hagen CE, Knopman DS, Jack CR, Petersen RC, Mielke MM. P3-221: Longitudinal Association Between Phosphatidylcholines, Neuroimaging Measures Of Alzheimer'S Disease Pathophysiology, And Cognition In The Mayo Clinic Study On Aging Alzheimers & Dementia. 14. DOI: 10.1016/J.Jalz.2018.06.1580  0.46
2017 González HM, Tarraf W, Harrison K, Windham BG, Tingle J, Alonso A, Griswold M, Heiss G, Knopman D, Mosley TH. Midlife cardiovascular health and 20-year cognitive decline: Atherosclerosis Risk in Communities Study results. Alzheimer's & Dementia : the Journal of the Alzheimer's Association. PMID 29268079 DOI: 10.1016/J.Jalz.2017.11.002  0.342
2017 Burns CM, Knopman DS, Tupper DE, Davey CS, Slinin YM, Lakshminarayan K, Rossom RC, Pederson SL, Gilbertson DT, Murray AM. Prevalence and Risk of Severe Cognitive Impairment in Advanced Chronic Kidney Disease. The Journals of Gerontology. Series a, Biological Sciences and Medical Sciences. PMID 29244090 DOI: 10.1093/Gerona/Glx241  0.304
2017 Wennberg AMV, Lesnick TG, Schwarz CG, Savica R, Hagen CE, Roberts RO, Knopman DS, Hollman JH, Vemuri P, Jack CR, Petersen RC, Mielke MM. Longitudinal association between brain amyloid beta and gait in the Mayo Clinic Study of Aging. The Journals of Gerontology. Series a, Biological Sciences and Medical Sciences. PMID 29236984 DOI: 10.1093/Gerona/Glx240  0.312
2017 Lowe VJ, Wiste HJ, Senjem ML, Weigand SD, Therneau TM, Boeve BF, Josephs KA, Fang P, Pandey MK, Murray ME, Kantarci K, Jones DT, Vemuri P, Graff-Radford J, Schwarz CG, ... ... Knopman DS, et al. Widespread brain tau and its association with ageing, Braak stage and Alzheimer's dementia. Brain : a Journal of Neurology. PMID 29228201 DOI: 10.1093/Brain/Awx320  0.479
2017 Graff-Radford J, Raman MR, Rabinstein AA, Przybelski SA, Lesnick TG, Boeve BF, Murray ME, Dickson DW, Reichard RR, Parisi JE, Knopman DS, Petersen RC, Jack CR, Kantarci K. Association Between Microinfarcts and Blood Pressure Trajectories. Jama Neurology. PMID 29204605 DOI: 10.1001/Jamaneurol.2017.3392  0.317
2017 Krell-Roesch J, Lowe VJ, Neureiter J, Pink A, Roberts RO, Mielke MM, Vemuri P, Stokin GB, Christianson TJ, Jack CR, Knopman DS, Boeve BF, Kremers WK, Petersen RC, Geda YE. Depressive and anxiety symptoms and cortical amyloid deposition among cognitively normal elderly persons: the Mayo Clinic Study of Aging. International Psychogeriatrics. 1-7. PMID 29198244 DOI: 10.1017/S1041610217002368  0.36
2017 Corriveau RA, Koroshetz WJ, Gladman JT, Jeon S, Babcock D, Bennett DA, Carmichael ST, Dickinson SL, Dickson DW, Emr M, Fillit H, Greenberg SM, Hutton ML, Knopman DS, Manly JJ, et al. Alzheimer's Disease-Related Dementias Summit 2016: National research priorities. Neurology. PMID 29117955 DOI: 10.1212/Wnl.0000000000004717  0.441
2017 Jones DT, Graff-Radford J, Lowe VJ, Wiste HJ, Gunter JL, Senjem ML, Botha H, Kantarci K, Boeve BF, Knopman DS, Petersen RC, Jack CR. Tau, amyloid, and cascading network failure across the Alzheimer's disease spectrum. Cortex; a Journal Devoted to the Study of the Nervous System and Behavior. PMID 29102243 DOI: 10.1016/J.Cortex.2017.09.018  0.37
2017 Yano Y, Butler KR, Hall ME, Schwartz GL, Knopman DS, Lirette ST, Jones DW, Wilson JG, Hall JE, Correa A, Turner ST, Mosley TH. Associations of Nocturnal Blood Pressure With Cognition by Self-Identified Race in Middle-Aged and Older Adults: The GENOA (Genetic Epidemiology Network of Arteriopathy) Study. Journal of the American Heart Association. 6. PMID 29079569 DOI: 10.1161/Jaha.117.007022  0.311
2017 Rabinovici GD, Carrillo MC, Forman M, DeSanti S, Miller DS, Kozauer N, Petersen RC, Randolph C, Knopman DS, Smith EE, Isaac M, Mattsson N, Bain LJ, Hendrix JA, Sims JR. Multiple comorbid neuropathologies in the setting of Alzheimer's disease neuropathology and implications for drug development. Alzheimer's & Dementia (New York, N. Y.). 3: 83-91. PMID 29067320 DOI: 10.1016/J.Trci.2016.09.002  0.432
2017 Roberts RO, Knopman DS, Syrjanen JA, Aakre JA, Vassilaki M, Kremers WK, Mielke MM, Machulda MM, Graff-Radford J, Geda YE, Vemuri P, Lowe V, Jack CR, Petersen RC. Weighting and standardization of frequencies to determine prevalence of AD imaging biomarkers. Neurology. PMID 29030451 DOI: 10.1212/Wnl.0000000000004652  0.311
2017 Vemuri P, Lesnick TG, Przybelski SA, Knopman DS, Lowe VJ, Graff-Radford J, Roberts RO, Mielke MM, Machulda MM, Petersen RC, Jack CR. Age, Vascular Health, and Alzheimer's disease Biomarkers in an Elderly Sample. Annals of Neurology. PMID 29023983 DOI: 10.1002/Ana.25071  0.368
2017 Graff-Radford J, Simino J, Kantarci K, Mosley TH, Griswold ME, Windham BG, Sharrett AR, Albert MS, Gottesman RF, Jack CR, Vemuri P, Knopman DS. Neuroimaging Correlates of Cerebral Microbleeds: The ARIC Study (Atherosclerosis Risk in Communities). Stroke. PMID 29018129 DOI: 10.1161/Strokeaha.117.018336  0.359
2017 Josephs KA, Dickson DW, Tosakulwong N, Weigand SD, Murray ME, Petrucelli L, Liesinger AM, Senjem ML, Spychalla AJ, Knopman DS, Parisi JE, Petersen RC, Jack CR, Whitwell JL. Rates of hippocampal atrophy and presence of post-mortem TDP-43 in patients with Alzheimer's disease: a longitudinal retrospective study. The Lancet. Neurology. PMID 28919059 DOI: 10.1016/S1474-4422(17)30284-3  0.372
2017 Power MC, Rawlings A, Sharrett AR, Bandeen-Roche K, Coresh J, Ballantyne CM, Pokharel Y, Michos ED, Penman A, Alonso A, Knopman D, Mosley TH, Gottesman RF. Association of midlife lipids with 20-year cognitive change: A cohort study. Alzheimer's & Dementia : the Journal of the Alzheimer's Association. PMID 28916238 DOI: 10.1016/J.Jalz.2017.07.757  0.364
2017 Bruinsma TJ, Johnson DR, Fang P, Senjem M, Josephs KA, Whitwell JL, Boeve BF, Pandey MK, Kantarci K, Jones DT, Vemuri P, Murray M, Graff-Radford J, Schwarz CG, Knopman DS, et al. Uptake of AV-1451 in meningiomas. Annals of Nuclear Medicine. PMID 28887599 DOI: 10.1007/S12149-017-1205-0  0.387
2017 Lowe VJ, Lundt E, Knopman D, Senjem ML, Gunter JL, Schwarz CG, Kemp BJ, Jack CR, Petersen RC. Comparison of [(18)F]Flutemetamol and [(11)C]Pittsburgh Compound-B in cognitively normal young, cognitively normal elderly, and Alzheimer's disease dementia individuals. Neuroimage. Clinical. 16: 295-302. PMID 28856092 DOI: 10.1016/J.Nicl.2017.08.011  0.391
2017 Gottesman RF, Albert MS, Alonso A, Coker LH, Coresh J, Davis SM, Deal JA, McKhann GM, Mosley TH, Sharrett AR, Schneider ALC, Windham BG, Wruck LM, Knopman DS. Associations Between Midlife Vascular Risk Factors and 25-Year Incident Dementia in the Atherosclerosis Risk in Communities (ARIC) Cohort. Jama Neurology. PMID 28783817 DOI: 10.1001/Jamaneurol.2017.1658  0.358
2017 Lee JS, Jung NY, Jang YK, Kim HJ, Seo SW, Lee J, Kim YJ, Lee JH, Kim BC, Park KW, Yoon SJ, Jeong JH, Kim SY, Kim SH, Kim EJ, ... ... Knopman DS, et al. Prognosis of Patients with Behavioral Variant Frontotemporal Dementia Who have Focal Versus Diffuse Frontal Atrophy. Journal of Clinical Neurology (Seoul, Korea). 13: 234-242. PMID 28748674 DOI: 10.3988/Jcn.2017.13.3.234  0.319
2017 Alonso A, Knopman DS, Gottesman RF, Soliman EZ, Shah AJ, O'Neal WT, Norby FL, Mosley TH, Chen LY. Correlates of Dementia and Mild Cognitive Impairment in Patients With Atrial Fibrillation: The Atherosclerosis Risk in Communities Neurocognitive Study (ARIC-NCS). Journal of the American Heart Association. 6. PMID 28739861 DOI: 10.1161/Jaha.117.006014  0.407
2017 Mielke MM, Hagen CE, Wennberg AMV, Airey DC, Savica R, Knopman DS, Machulda MM, Roberts RO, Jack CR, Petersen RC, Dage JL. Association of Plasma Total Tau Level With Cognitive Decline and Risk of Mild Cognitive Impairment or Dementia in the Mayo Clinic Study on Aging. Jama Neurology. PMID 28692710 DOI: 10.1001/Jamaneurol.2017.1359  0.435
2017 Zeydan B, Deelchand DK, Tosakulwong N, Lesnick TG, Kantarci OH, Machulda MM, Knopman DS, Lowe VJ, Jack CR, Petersen RC, Öz G, Kantarci K. Decreased Glutamate Levels in Patients with Amnestic Mild Cognitive Impairment: An sLASER Proton MR Spectroscopy and PiB-PET Study. Journal of Neuroimaging : Official Journal of the American Society of Neuroimaging. PMID 28661060 DOI: 10.1111/Jon.12454  0.342
2017 Jung Y, Boot BP, Mielke MM, Ferman TJ, Geda YE, McDade E, Christianson TJH, Knopman DS, St Louis EK, Silber MH, Petersen RC, Boeve BF. Phenoconversion from probable rapid eye movement sleep behavior disorder to mild cognitive impairment to dementia in a population-based sample. Alzheimer's & Dementia (Amsterdam, Netherlands). 8: 127-130. PMID 28649596 DOI: 10.1016/J.Dadm.2017.05.004  0.384
2017 Caselli RJ, Beach TG, Knopman DS, Graff-Radford NR. Alzheimer Disease: Scientific Breakthroughs and Translational Challenges. Mayo Clinic Proceedings. 92: 978-994. PMID 28578785 DOI: 10.1016/j.mayocp.2017.02.011  0.406
2017 Kantarci K, Murray ME, Schwarz CG, Reid RI, Przybelski SA, Lesnick T, Zuk SM, Raman MR, Senjem ML, Gunter JL, Boeve BF, Knopman DS, Parisi JE, Petersen RC, Jack CR, et al. White-matter integrity on DTI and the pathologic staging of Alzheimer's disease. Neurobiology of Aging. PMID 28552181 DOI: 10.1016/J.Neurobiolaging.2017.04.024  0.383
2017 Vassilaki M, Christianson TJ, Mielke MM, Geda YE, Kremers WK, Machulda MM, Knopman DS, Petersen RC, Lowe VJ, Jack CR, Roberts RO. Neuroimaging Biomarkers and Impaired Olfaction in Cognitively Normal Individuals. Annals of Neurology. PMID 28543731 DOI: 10.1002/Ana.24960  0.448
2017 Knopman DS, Nestor PJ. Beyond clinical syndromes in primary progressive aphasia: Seeking etiologic diagnoses. Neurology. 88: 2244-2245. PMID 28515274 DOI: 10.1212/Wnl.0000000000004041  0.317
2017 Jack CR, Wiste HJ, Weigand SD, Therneau TM, Knopman DS, Lowe V, Vemuri P, Mielke MM, Roberts RO, Machulda MM, Senjem ML, Gunter JL, Rocca WA, Petersen RC. Age-specific and sex-specific prevalence of cerebral β-amyloidosis, tauopathy, and neurodegeneration in cognitively unimpaired individuals aged 50-95 years: a cross-sectional study. The Lancet. Neurology. PMID 28456479 DOI: 10.1016/S1474-4422(17)30077-7  0.415
2017 Vemuri P, Knopman DS, Lesnick TG, Przybelski SA, Mielke MM, Graff-Radford J, Murray ME, Roberts RO, Vassilaki M, Lowe VJ, Machulda MM, Jones DT, Petersen RC, Jack CR. Evaluation of Amyloid Protective Factors and Alzheimer Disease Neurodegeneration Protective Factors in Elderly Individuals. Jama Neurology. PMID 28418521 DOI: 10.1001/Jamaneurol.2017.0244  0.361
2017 Gottesman RF, Schneider AL, Zhou Y, Coresh J, Green E, Gupta N, Knopman DS, Mintz A, Rahmim A, Sharrett AR, Wagenknecht LE, Wong DF, Mosley TH. Association Between Midlife Vascular Risk Factors and Estimated Brain Amyloid Deposition. Jama. 317: 1443-1450. PMID 28399252 DOI: 10.1001/Jama.2017.3090  0.307
2017 Relkin NR, Thomas RG, Rissman RA, Brewer JB, Rafii MS, van Dyck CH, Jack CR, Sano M, Knopman DS, Raman R, Szabo P, Gelmont DM, Fritsch S, Aisen PS. A phase 3 trial of IV immunoglobulin for Alzheimer disease. Neurology. PMID 28381506 DOI: 10.1212/Wnl.0000000000003904  0.308
2017 Dearborn JL, Zhang Y, Qiao Y, Suri MF, Liu L, Gottesman RF, Rawlings AM, Mosley TH, Alonso A, Knopman DS, Guallar E, Wasserman BA. Intracranial atherosclerosis and dementia: The Atherosclerosis Risk in Communities (ARIC) Study. Neurology. PMID 28330958 DOI: 10.1212/Wnl.0000000000003837  0.451
2017 Sprung J, Roberts RO, Knopman DS, Price LL, Schulz HP, Tatsuyama CL, Weingarten TN, Schroeder DR, Hanson AC, Petersen RC, Warner DO. Mild Cognitive Impairment and Exposure to General Anesthesia for Surgeries and Procedures: A Population-Based Case-Control Study. Anesthesia and Analgesia. PMID 28291057 DOI: 10.1213/Ane.0000000000001725  0.364
2017 Wiepert DA, Lowe VJ, Knopman DS, Boeve BF, Graff-Radford J, Petersen RC, Jack CR, Jones DT. A robust biomarker of large-scale network failure in Alzheimer's disease. Alzheimer's & Dementia (Amsterdam, Netherlands). 6: 152-161. PMID 28275697 DOI: 10.1016/J.Dadm.2017.01.004  0.308
2017 Meyer ML, Palta P, Tanaka H, Deal JA, Wright J, Knopman DS, Griswold M, Mosley TH, Heiss G. Association of Central Arterial Stiffness and Pressure Pulsatility with Mild Cognitive Impairment and Dementia: The Atherosclerosis Risk in Communities Study-Neurocognitive Study (ARIC-NCS). Journal of Alzheimer's Disease : Jad. PMID 28222517 DOI: 10.3233/Jad-161041  0.391
2017 Josephs KA, Murray ME, Tosakulwong N, Whitwell JL, Knopman DS, Machulda MM, Weigand SD, Boeve BF, Kantarci K, Petrucelli L, Lowe VJ, Jack CR, Petersen RC, Parisi JE, Dickson DW. Tau aggregation influences cognition and hippocampal atrophy in the absence of beta-amyloid: a clinico-imaging-pathological study of primary age-related tauopathy (PART). Acta Neuropathologica. PMID 28160067 DOI: 10.1007/S00401-017-1681-2  0.39
2017 Vemuri P, Lowe VJ, Knopman DS, Senjem ML, Kemp BJ, Schwarz CG, Przybelski SA, Machulda MM, Petersen RC, Jack CR. Tau-PET uptake: Regional variation in average SUVR and impact of amyloid deposition. Alzheimer's & Dementia (Amsterdam, Netherlands). 6: 21-30. PMID 28138510 DOI: 10.1016/J.Dadm.2016.12.010  0.348
2017 Krell-Roesch J, Vemuri P, Pink A, Roberts RO, Stokin GB, Mielke MM, Christianson TJ, Knopman DS, Petersen RC, Kremers WK, Geda YE. Association Between Mentally Stimulating Activities in Late Life and the Outcome of Incident Mild Cognitive Impairment, With an Analysis of the APOE ε4 Genotype. Jama Neurology. PMID 28135351 DOI: 10.1001/Jamaneurol.2016.3822  0.38
2017 Graff-Radford J, Aakre J, Savica R, Boeve B, Kremers WK, Ferman TJ, Jones DT, Kantarci K, Knopman DS, Dickson DW, Kukull WA, Petersen RC. Duration and Pathologic Correlates of Lewy Body Disease. Jama Neurology. PMID 28114455 DOI: 10.1001/Jamaneurol.2016.4926  0.381
2017 Hibar DP, Adams HH, Jahanshad N, Chauhan G, Stein JL, Hofer E, Renteria ME, Bis JC, Arias-Vasquez A, Ikram MK, Desrivières S, Vernooij MW, Abramovic L, Alhusaini S, Amin N, ... ... Knopman DS, et al. Novel genetic loci associated with hippocampal volume. Nature Communications. 8: 13624. PMID 28098162 DOI: 10.1038/Ncomms13624  0.303
2017 Li D, Misialek JR, Boerwinkle E, Gottesman RF, Sharrett AR, Mosley TH, Coresh J, Wruck LM, Knopman DS, Alonso A. Prospective associations of plasma phospholipids and mild cognitive impairment/dementia among African Americans in the ARIC Neurocognitive Study. Alzheimer's & Dementia (Amsterdam, Netherlands). 6: 1-10. PMID 28054030 DOI: 10.1016/J.Dadm.2016.09.003  0.407
2017 Graff-Radford J, Przybelski SA, Lesnick TG, Rabinstein A, Flemming K, Brown RD, Mielke MM, Spychalla AJ, Vemuri P, Lowe V, Knopman DS, Petersen RC, Jack CR, Kantarci K. Cerebral Microbleeds And Amyloid Burden: The Mayo Clinic Study Of Aging Alzheimers & Dementia. 13: 1237. DOI: 10.1016/J.Jalz.2017.07.440  0.325
2017 Griswold ME, Su D, Tingle JV, Wilkening SR, Rawlings A, Deal JA, Bandeen-Roche K, Gottesman RF, Knopman DS, Windham BG, Mosley TH. EFFECTS OF CEREBROVASCULAR INFARCT BURDEN ON COGNITIVE DECLINE IN THE PRESENCE OF DEMENTIA AND DEATH: ACCOUNTING FOR POTENTIALLY INFORMATIVE DROPOUT USING COMPETING RISK SHARED PARAMETER MODELS: THE ARIC STUDY Alzheimer's & Dementia. 13: P586. DOI: 10.1016/J.Jalz.2017.07.213  0.372
2017 Knopman DS, Jack CR, Lundt ES, Weigand SD, Vemuri P, Lowe V, Kantarci K, Gunter JL, Senjem ML, Mielke MM, Machulda MM, Roberts RO, Boeve BF, Jones DT, Therneau TM, et al. CONTINUOUS MEASURES OF β-AMYLOIDOSIS AND CORTICAL THICKNESS IN RELATION TO COGNITIVE DECLINE IN COGNITIVELY NORMAL INDIVIDUALS: A POPULATION-BASED STUDY Alzheimers & Dementia. 13. DOI: 10.1016/J.Jalz.2017.07.105  0.363
2017 Windham BG, Wilkening SR, Tingle JV, Coker L, Knopman DS, Su D, Gottesman RF, Griswold ME, Mosley TH. Relationships Of Very Small, Infarct-Like Lesions With 20-Year Cognitive Decline: The Aric Study Alzheimers & Dementia. 13: 211. DOI: 10.1016/J.Jalz.2017.07.083  0.327
2017 Hughes SR, Boeve BF, Rosen HJ, Boxer AL, Calvert KJ, Dheel C, Dickerson BC, Fields JA, Gavrilova RH, Ghoshal N, Goldman J, Graff-Radford NR, Grossman M, Heuer H, Hsiung GR, ... ... Knopman DS, et al. Caregiver Burden In Familial Frontotemporal Dementia Subjects: Preliminary Data In The Lefftds Cohort Alzheimers & Dementia. 13. DOI: 10.1016/J.Jalz.2017.06.934  0.313
2017 Wennberg AM, Lesnick TG, Schwarz CG, Knopman DS, Savica R, Hollman JH, Jack CR, Petersen RC, Mielke MM. [P1-457]: LONGITUDINAL ASSOCIATIONS BETWEEN CEREBRAL AMYLOID DEPOSITION, CORTICAL THICKNESS, AND GAIT IN THE MAYO CLINIC STUDY OF AGING Alzheimer's & Dementia. 13: P461-P462. DOI: 10.1016/J.Jalz.2017.06.473  0.329
2017 Giebel C, Mioshi E, Knopman DS, Khondoker M. Decline In Instrumental Activities Of Daily Living Is More Marked In Behavioural Variant Frontotemporal Dementia Than In Alzheimer’S Disease Alzheimers & Dementia. 13: 385. DOI: 10.1016/J.Jalz.2017.06.352  0.386
2017 Boeve BF, Ross OA, Kantarci K, Ferman TJ, Graff-Radford NR, Radford JG, Jones DT, Savica R, Przybelski SA, Mielke MM, Knopman DS, Jack CR, Lowe V, Petersen RC. Characterization Of The Clinical And Neuroimaging Features Of Patients With Dementia With Lewy Bodies Associated With Variants In Glucocerebrosidase (Gba) Alzheimers & Dementia. 13: 384. DOI: 10.1016/J.Jalz.2017.06.350  0.348
2017 Dheel CM, Boeve BF, Rosen HJ, Boxer AL, Coppola G, Dickerson BC, Faber K, Fields JA, Foroud TM, Gavrilova RH, Ghoshal N, Goldman J, Graff-Radford N, Grossman M, Heuer H, ... ... Knopman DS, et al. [P1-254]: CHARACTERISTICS AND PROGRESS ON THE INITIAL 209 SUBJECTS IN THE LONGITUDINAL EVALUATION OF FAMILIAL FRONTOTEMPORAL DEMENTIA SUBJECTS (LEFFTDS) PROTOCOL Alzheimer's & Dementia. 13: P345-P345. DOI: 10.1016/J.Jalz.2017.06.270  0.313
2017 Nedelska Z, Senjem ML, Boeve BF, Przybelski SA, Lesnick TG, Vemuri P, Lowe V, Graff-Radford J, Ferman TJ, Knopman DS, Petersen RC, Jack CR, Kantarci K. Pattern Of Hypoperfusion On Asl Overlaps With Hypometabolism On Fdg-Pet In Dementia With Lewy Bodies Alzheimers & Dementia. 13. DOI: 10.1016/J.Jalz.2017.06.2348  0.305
2017 Corien van Harten A, Hagen CE, Edwards K, Mielke MM, Swenson-Dravis D, Knopman DS, Roberts RO, Geda YE, Petersen RC. [P4-179]: ASPECTS OF SUBJECTIVE COGNITIVE DECLINE THAT PREDICT INCIDENT MCI IN THE MAYO CLINC STUDY OF AGING Alzheimer's & Dementia. 13: P1331-P1331. DOI: 10.1016/J.Jalz.2017.06.2046  0.388
2017 Graff-Radford NR, Gunter JL, Thomas CS, Crook JE, Jones DT, Graff-Radford J, Boeve BF, Knopman DS, Petersen RC, Jack CR. Ventriculomegaly Is A Biomarker Of Gait And Cognitive Decline Alzheimers & Dementia. 13: 1092. DOI: 10.1016/J.Jalz.2017.06.1572  0.381
2017 Mielke MM, Hagen CE, Wennberg AM, Airey DC, Savica R, Knopman DS, Machulda MM, Roberts RO, Lowe V, Jack CR, Petersen RC, Dage JL. [P3-242]: PLASMA TOTAL TAU, COGNITIVE DECLINE, AND RISK OF MILD COGNITIVE IMPAIRMENT IN THE MAYO CLINIC STUDY ON AGING Alzheimer's & Dementia. 13: P1032-P1033. DOI: 10.1016/J.Jalz.2017.06.1455  0.42
2017 Savica R, Knopman DS. Dementia with Lewy Bodies Neurology. 83: 83-92. DOI: 10.1002/9781118661895.Ch9  0.342
2016 Carvalho DZ, St Louis EK, Boeve BF, Mielke MM, Przybelski SA, Knopman DS, Machulda MM, Roberts RO, Geda YE, Petersen RC, Jack CR, Vemuri P. Excessive daytime sleepiness and fatigue may indicate accelerated brain aging in cognitively normal late middle-aged and older adults. Sleep Medicine. PMID 28065685 DOI: 10.1016/J.Sleep.2016.08.023  0.345
2016 Snyder HM, Ahles T, Calderwood S, Carrillo MC, Chen H, Chang CC, Craft S, De Jager P, Driver JA, Fillet H, Knopman D, Lotze M, Tierney MC, Petanceska S, Saykin A, et al. Exploring the nexus of Alzheimer's disease and related dementias with cancer and cancer therapies. Alzheimer's & Dementia : the Journal of the Alzheimer's Association. PMID 27998721 DOI: 10.1016/J.Jalz.2016.11.002  0.354
2016 Iadecola C, Yaffe K, Biller J, Bratzke LC, Faraci FM, Gorelick PB, Gulati M, Kamel H, Knopman DS, Launer LJ, Saczynski JS, Seshadri S, Zeki Al Hazzouri A. Impact of Hypertension on Cognitive Function: A Scientific Statement From the American Heart Association. Hypertension (Dallas, Tex. : 1979). 68: e67-e94. PMID 27977393 DOI: 10.1161/Hyp.0000000000000053  0.415
2016 DeGrado TR, Kemp BJ, Pandey MK, Jiang H, Gunderson TM, Linscheid LR, Woodwick AR, McConnell DM, Fletcher JG, Johnson GB, Petersen RC, Knopman DS, Lowe VJ. First PET Imaging Studies With 63Zn-Zinc Citrate in Healthy Human Participants and Patients With Alzheimer Disease. Molecular Imaging. 15. PMID 27941122 DOI: 10.1177/1536012116673793  0.325
2016 Bressler J, Knopman DS, Sharrett AR, Gottesman RF, Penman A, Chang PP, Rosamond WD, Boerwinkle E, Mosley TH. Incident Heart Failure and Cognitive Decline: the Atherosclerosis Risk in Communities Study. Journal of Cardiac Failure. PMID 27864030 DOI: 10.1016/J.Cardfail.2016.11.002  0.375
2016 Kantarci K, Lowe VJ, Boeve BF, Senjem ML, Tosakulwong N, Lesnick TG, Spychalla AJ, Gunter JL, Fields JA, Graff-Radford J, Ferman TJ, Jones DT, Murray ME, Knopman DS, Jack CR, et al. AV-1451 Tau and β-Amyloid PET Imaging in Dementia with Lewy Bodies. Annals of Neurology. PMID 27863444 DOI: 10.1002/Ana.24825  0.387
2016 Kantarci K, Lesnick T, Ferman TJ, Przybelski SA, Boeve BF, Smith GE, Kremers WK, Knopman DS, Jack CR, Petersen RC. Hippocampal volumes predict risk of dementia with Lewy bodies in mild cognitive impairment. Neurology. PMID 27807186 DOI: 10.1212/Wnl.0000000000003371  0.404
2016 Krell-Roesch J, Pink A, Roberts RO, Stokin GB, Mielke MM, Spangehl KA, Bartley MM, Knopman DS, Christianson TJ, Petersen RC, Geda YE. Timing of Physical Activity, Apolipoprotein E ε4 Genotype, and Risk of Incident Mild Cognitive Impairment. Journal of the American Geriatrics Society. PMID 27801933 DOI: 10.1111/Jgs.14402  0.367
2016 Bressler J, Mosley TH, Penman A, Gottesman RF, Windham BG, Knopman DS, Wruck LM, Boerwinkle E. Genetic variants associated with risk of Alzheimer's disease contribute to cognitive change in midlife: The Atherosclerosis Risk in Communities Study. American Journal of Medical Genetics. Part B, Neuropsychiatric Genetics : the Official Publication of the International Society of Psychiatric Genetics. PMID 27781389 DOI: 10.1002/Ajmg.B.32509  0.392
2016 Machulda MM, Hagen CE, Wiste HJ, Mielke MM, Knopman DS, Roberts RO, Vemuri P, Lowe VJ, Jack CR, Petersen RC. Practice effects and longitudinal cognitive change in clinically normal older adults differ by Alzheimer imaging biomarker status. The Clinical Neuropsychologist. 1-19. PMID 27724156 DOI: 10.1080/13854046.2016.1241303  0.426
2016 Knopman DS. Alzheimer disease: Preclinical Alzheimer disease [mdash] the new frontier Nature Reviews Neurology. 12: 620-621. PMID 27713487 DOI: 10.1038/Nrneurol.2016.153  0.445
2016 Jack CR, Wiste HJ, Weigand SD, Therneau TM, Lowe VJ, Knopman DS, Gunter JL, Senjem ML, Jones DT, Kantarci K, Machulda MM, Mielke MM, Roberts RO, Vemuri P, Reyes D, et al. Defining imaging biomarker cut points for brain aging and Alzheimer's disease. Alzheimer's & Dementia : the Journal of the Alzheimer's Association. PMID 27697430 DOI: 10.1016/J.Jalz.2016.08.005  0.323
2016 Savica R, Wennberg AM, Hagen C, Edwards K, Roberts RO, Hollman JH, Knopman DS, Boeve BF, Machulda MM, Petersen RC, Mielke MM. Comparison of Gait Parameters for Predicting Cognitive Decline: The Mayo Clinic Study of Aging. Journal of Alzheimer's Disease : Jad. PMID 27662317 DOI: 10.3233/Jad-160697  0.38
2016 Pottier C, Ravenscroft TA, Brown PH, Finch NA, Baker M, Parsons M, Asmann YW, Ren Y, Christopher E, Levitch D, van Blitterswijk M, Cruchaga C, Campion D, Nicolas G, Richard AC, ... ... Knopman DS, et al. TYROBP genetic variants in early-onset Alzheimer's disease. Neurobiology of Aging. PMID 27658901 DOI: 10.1016/J.Neurobiolaging.2016.07.028  0.363
2016 Pink A, Przybelski SA, Krell-Roesch J, Stokin GB, Roberts RO, Mielke MM, Spangehl KA, Knopman DS, Jack CR, Petersen RC, Geda YE. Cortical Thickness and Anxiety Symptoms Among Cognitively Normal Elderly Persons: The Mayo Clinic Study of Aging. The Journal of Neuropsychiatry and Clinical Neurosciences. appineuropsych151003. PMID 27578447 DOI: 10.1176/Appi.Neuropsych.15100378  0.316
2016 Sarro L, Tosakulwong N, Schwarz CG, Graff-Radford J, Przybelski SA, Lesnick TG, Zuk SM, Reid RI, Raman MR, Boeve BF, Ferman TJ, Knopman DS, Comi G, Filippi M, Murray ME, et al. An investigation of cerebrovascular lesions in dementia with Lewy bodies compared to Alzheimer's disease. Alzheimer's & Dementia : the Journal of the Alzheimer's Association. PMID 27521790 DOI: 10.1016/J.Jalz.2016.07.003  0.408
2016 Heckman MG, Soto-Ortolaza AI, Sanchez Contreras MY, Murray ME, Pedraza O, Diehl NN, Walton R, Labbé C, Lorenzo-Betancor O, Uitti RJ, van Gerpen J, Ertekin-Taner N, Smith GE, Kantarci K, Savica R, ... ... Knopman DS, et al. LRRK2 variation and dementia with Lewy bodies. Parkinsonism & Related Disorders. PMID 27521182 DOI: 10.1016/J.Parkreldis.2016.07.015  0.316
2016 Mioshi E, Flanagan E, Knopman D. Detecting clinical change with the CDR-FTLD: differences between FTLD and AD dementia. International Journal of Geriatric Psychiatry. PMID 27464599 DOI: 10.1002/Gps.4556  0.41
2016 Staubo SC, Aakre JA, Vemuri P, Syrjanen JA, Mielke MM, Geda YE, Kremers WK, Machulda MM, Knopman DS, Petersen RC, Jack CR, Roberts RO. Mediterranean diet, micronutrients and macronutrients, and MRI measures of cortical thickness. Alzheimer's & Dementia : the Journal of the Alzheimer's Association. PMID 27461490 DOI: 10.1016/J.Jalz.2016.06.2359  0.349
2016 Knopman DS, Jack CR, Lundt ES, Weigand SD, Vemuri P, Lowe VJ, Kantarci K, Gunter JL, Senjem ML, Mielke MM, Machulda MM, Roberts RO, Boeve BF, Jones DT, Petersen RC. Evolution of neurodegeneration-imaging biomarkers from clinically normal to dementia in the Alzheimer disease spectrum. Neurobiology of Aging. 46: 32-42. PMID 27460147 DOI: 10.1016/J.Neurobiolaging.2016.06.003  0.443
2016 Hodges K, Brewer SS, Labbé C, Soto-Ortolaza AI, Walton RL, Strongosky AJ, Uitti RJ, van Gerpen JA, Ertekin-Taner N, Kantarci K, Lowe VJ, Parisi JE, Savica R, Graff-Radford J, Jones DT, ... Knopman DS, et al. RAB39B gene mutations are not a common cause of Parkinson's disease or dementia with Lewy bodies. Neurobiology of Aging. 45: 107-108. PMID 27459931 DOI: 10.1016/J.Neurobiolaging.2016.03.021  0.307
2016 Walton RL, Soto-Ortolaza AI, Murray ME, Lorenzo-Betancor O, Ogaki K, Heckman MG, Rayaprolu S, Rademakers R, Ertekin-Taner N, Uitti RJ, van Gerpen JA, Wszolek ZK, Smith GE, Kantarci K, Lowe VJ, ... ... Knopman DS, et al. TREM2 p.R47H substitution is not associated with dementia with Lewy bodies. Neurology. Genetics. 2: e85. PMID 27458607 DOI: 10.1212/Nxg.0000000000000085  0.425
2016 Sarro L, Senjem ML, Lundt ES, Przybelski SA, Lesnick TG, Graff-Radford J, Boeve BF, Lowe VJ, Ferman TJ, Knopman DS, Comi G, Filippi M, Petersen RC, Jack CR, Kantarci K. Amyloid-β deposition and regional grey matter atrophy rates in dementia with Lewy bodies. Brain : a Journal of Neurology. PMID 27452602 DOI: 10.1093/Brain/Aww193  0.394
2016 Krell-Roesch J, Ruider H, Lowe VJ, Stokin GB, Pink A, Roberts RO, Mielke MM, Knopman DS, Christianson TJ, Machulda MM, Jack CR, Petersen RC, Geda YE. FDG-PET and Neuropsychiatric Symptoms among Cognitively Normal Elderly Persons: The Mayo Clinic Study of Aging. Journal of Alzheimer's Disease : Jad. PMID 27447426 DOI: 10.3233/Jad-160326  0.381
2016 Dage JL, Wennberg AM, Airey DC, Hagen CE, Knopman DS, Machulda MM, Roberts RO, Jack CR, Petersen RC, Mielke MM. Levels of tau protein in plasma are associated with neurodegeneration and cognitive function in a population-based elderly cohort. Alzheimer's & Dementia : the Journal of the Alzheimer's Association. PMID 27436677 DOI: 10.1016/J.Jalz.2016.06.001  0.374
2016 Knopman DS, Jack CR, Wiste HJ, Weigand SD, Vemuri P, Lowe VJ, Kantarci K, Gunter JL, Senjem ML, Mielke MM, Machulda MM, Roberts RO, Boeve BF, Jones DT, Petersen RC. Age and neurodegeneration imaging biomarkers in persons with Alzheimer disease dementia. Neurology. PMID 27421543 DOI: 10.1212/Wnl.0000000000002979  0.42
2016 Li D, Misialek JR, Boerwinkle E, Gottesman RF, Sharrett AR, Mosley TH, Coresh J, Wruck LM, Knopman DS, Alonso A. Plasma phospholipids and prevalence of mild cognitive impairment and/or dementia in the ARIC Neurocognitive Study (ARIC-NCS). Alzheimer's & Dementia (Amsterdam, Netherlands). 3: 73-82. PMID 27408938 DOI: 10.1016/J.Dadm.2016.02.008  0.427
2016 Jack CR, Bennett DA, Blennow K, Carrillo MC, Feldman HH, Frisoni GB, Hampel H, Jagust WJ, Johnson KA, Knopman DS, Petersen RC, Scheltens P, Sperling RA, Dubois B. A/T/N: An unbiased descriptive classification scheme for Alzheimer disease biomarkers. Neurology. PMID 27371494 DOI: 10.1212/Wnl.0000000000002923  0.397
2016 Gottesman RF, Schneider AL, Zhou Y, Chen X, Green E, Gupta N, Knopman DS, Mintz A, Rahmim A, Sharrett AR, Wagenknecht LE, Wong DF, Mosley TH. The ARIC-PET amyloid imaging study: Brain amyloid differences by age, race, sex, and APOE. Neurology. PMID 27371485 DOI: 10.1212/Wnl.0000000000002914  0.354
2016 Lowe VJ, Curran G, Fang P, Liesinger AM, Josephs KA, Parisi JE, Kantarci K, Boeve BF, Pandey MK, Bruinsma T, Knopman DS, Jones DT, Petrucelli L, Cook CN, Graff-Radford NR, et al. An autoradiographic evaluation of AV-1451 Tau PET in dementia. Acta Neuropathologica Communications. 4: 58. PMID 27296779 DOI: 10.1186/S40478-016-0315-6  0.367
2016 Labbé C, Heckman MG, Lorenzo-Betancor O, Soto-Ortolaza AI, Walton RL, Murray ME, Allen M, Uitti RJ, Wszolek ZK, Smith GE, Kantarci K, Knopman DS, Lowe VJ, Jack CR, Ertekin-Taner N, et al. MAPT haplotype H1G is associated with increased risk of dementia with Lewy bodies. Alzheimer's & Dementia : the Journal of the Alzheimer's Association. PMID 27287057 DOI: 10.1016/J.Jalz.2016.05.002  0.362
2016 Pakhomov SV, Eberly L, Knopman D. Characterizing cognitive performance in a large longitudinal study of aging with computerized semantic indices of verbal fluency. Neuropsychologia. 89: 42-56. PMID 27245645 DOI: 10.1016/J.Neuropsychologia.2016.05.031  0.403
2016 Graff-Radford J, Lesnick TG, Boeve BF, Przybelski SA, Jones DT, Senjem ML, Gunter JL, Ferman TJ, Knopman DS, Murray ME, Dickson DW, Sarro L, Jack CR, Petersen RC, Kantarci K. Predicting Survival in Dementia With Lewy Bodies With Hippocampal Volumetry. Movement Disorders : Official Journal of the Movement Disorder Society. PMID 27214825 DOI: 10.1002/Mds.26666  0.329
2016 Vassilaki M, Aakre JA, Mielke MM, Geda YE, Kremers WK, Alhurani RE, Machulda MM, Knopman DS, Petersen RC, Lowe VJ, Jack CR, Roberts RO. Multimorbidity and neuroimaging biomarkers among cognitively normal persons. Neurology. PMID 27164657 DOI: 10.1212/Wnl.0000000000002624  0.376
2016 Wennberg AM, Gustafson D, Hagen CE, Roberts RO, Knopman D, Jack C, Petersen RC, Mielke MM. Serum Adiponectin Levels, Neuroimaging, and Cognition in the Mayo Clinic Study of Aging. Journal of Alzheimer's Disease : Jad. PMID 27163809 DOI: 10.3233/Jad-151201  0.464
2016 Jaeger PA, Lucin KM, Britschgi M, Vardarajan B, Huang RP, Kirby ED, Abbey R, Boeve BF, Boxer AL, Farrer LA, Finch N, Graff-Radford NR, Head E, Hoffree M, Huang R, ... ... Knopman DS, et al. Network-driven plasma proteomics expose molecular changes in the Alzheimer's brain. Molecular Neurodegeneration. 11: 31. PMID 27112350 DOI: 10.1186/S13024-016-0095-2  0.352
2016 Kats D, Patel MD, Palta P, Meyer ML, Gross AL, Whitsel EA, Knopman D, Alonso A, Mosley TH, Heiss G. Social support and cognition in a community-based cohort: the Atherosclerosis Risk in Communities (ARIC) study. Age and Ageing. PMID 27107128 DOI: 10.1093/Ageing/Afw060  0.364
2016 Rabinovici GD, Karlawish J, Knopman D, Snyder HM, Sperling R, Carrillo MC. Testing and disclosures related to amyloid imaging and Alzheimer's disease: Common questions and fact sheet summary. Alzheimer's & Dementia : the Journal of the Alzheimer's Association. 12: 510-5. PMID 27103054 DOI: 10.1016/J.Jalz.2016.03.002  0.425
2016 Schott JM, Crutch SJ, Carrasquillo MM, Uphill J, Shakespeare TJ, Ryan NS, Yong KX, Lehmann M, Ertekin-Taner N, Graff-Radford NR, Boeve BF, Murray ME, Khan QU, Petersen RC, Dickson DW, ... Knopman DS, et al. Genetic risk factors for the posterior cortical atrophy variant of Alzheimer's disease. Alzheimer's & Dementia : the Journal of the Alzheimer's Association. PMID 26993346 DOI: 10.1016/J.Jalz.2016.01.010  0.354
2016 Knopman DS, Gottesman RF, Sharrett AR, Wruck LM, Windham BG, Coker L, Schneider AL, Hengrui S, Alonso A, Coresh J, Albert MS, Mosley TH. Mild Cognitive Impairment and Dementia Prevalence: The Atherosclerosis Risk in Communities Neurocognitive Study (ARIC-NCS). Alzheimer's & Dementia (Amsterdam, Netherlands). 2: 1-11. PMID 26949733 DOI: 10.1016/J.Dadm.2015.12.002  0.41
2016 Vemuri P, Lesnick TG, Przybelski SA, Knopman DS, Machulda M, Lowe VJ, Mielke MM, Roberts RO, Gunter JL, Senjem ML, Geda YE, Rocca WA, Petersen RC, Jack CR. Effect of intellectual enrichment on AD biomarker trajectories: Longitudinal imaging study. Neurology. PMID 26911640 DOI: 10.1212/Wnl.0000000000002490  0.415
2016 Sprung J, Roberts RO, Knopman DS, Petersen RC, Weingarten TN, Schroeder DR, Warner DO. Perioperative Delirium and Mild Cognitive Impairment. Mayo Clinic Proceedings. 91: 273-4. PMID 26848007 DOI: 10.1016/j.mayocp.2015.12.008  0.313
2016 Alhurani RE, Vassilaki M, Aakre JA, Mielke MM, Kremers WK, Machulda MM, Geda YE, Knopman DS, Peterson RC, Roberts RO. Decline in Weight and Incident Mild Cognitive Impairment: Mayo Clinic Study of Aging. Jama Neurology. PMID 26831542 DOI: 10.1001/Jamaneurol.2015.4756  0.403
2016 Jack CR, Knopman DS, Chételat G, Dickson D, Fagan AM, Frisoni GB, Jagust W, Mormino EC, Petersen RC, Sperling RA, van der Flier WM, Villemagne VL, Visser PJ, Vos SJ. Suspected non-Alzheimer disease pathophysiology - concept and controversy. Nature Reviews. Neurology. PMID 26782335 DOI: 10.1038/Nrneurol.2015.251  0.439
2016 Knopman DS, Martin Y, Sprung J, Roberts RO, Warner D, Petersen RC. Association Of Mild Cognitive Impairment With Exposure To General Anesthesia For Surgical And Non-Surgical Procedures In Olmsted County, Minnesota Alzheimers & Dementia. 12: 367. DOI: 10.1016/J.Jalz.2016.06.686  0.315
2016 Li D, Misialek J, Boerwinkle E, Gottesman RF, Sharrett R, Mosley T, Coresh J, Wruck L, Knopman DS, Alonso A. O4-10-05: PLASMA PHOSPHOLIPIDS AND INCIDENT MILD COGNITIVE IMPAIRMENT/DEMENTIA IN THE ARIC NEUROCOGNITIVE STUDY (ARIC-NCS) Alzheimer's & Dementia. 12: P359-P359. DOI: 10.1016/J.Jalz.2016.06.664  0.389
2016 Kantarci K, Lowe VJ, Boeve BF, Senjem ML, Tosakulwong N, Spychalla AJ, Ferman TJ, Jones DT, Graff-Radford J, Murray ME, Knopman DS, Jack CR, Petersen RC. Pattern Of Av-1451 Uptake In Dementia With Lewy Bodies And Its Association With Amyloid-Beta Deposition Alzheimers & Dementia. 12. DOI: 10.1016/J.Jalz.2016.06.606  0.311
2016 Knopman DS, Wiste HJ, Jack CR, Petersen RC, Boeve BF, Kantarci K, Jones DT, Mielke MM, Roberts RO, Weigand SD, Graff-Radford J, Vemuri P, Machulda MM, Lowe VJ. Av1451 Pet Imaging In The Spectrum Of Alzheimer’S Disease From Clinically Normal To Dementia Alzheimers & Dementia. 12. DOI: 10.1016/J.Jalz.2016.06.436  0.365
2016 Knopman DS, Wang W, Whitmer RA, Launer LJ, Seshadri S, Kalaria RN, Prince MJ, Snyder HM, Carrillo MC, Amouyel P. Epidemiology Of Vascular Related Risk Factors For Dementia Alzheimers & Dementia. 12: 276. DOI: 10.1016/J.Jalz.2016.06.2384  0.315
2016 San Lee J, Jung NY, Kim E, Lee J, Jang YK, Kim YJ, Kim HJ, Seo SW, Lee J, Kim BC, Park K, Yoon SJ, Jeong JH, Kim S, Park K, ... Knopman DS, et al. P4-219: The Diffuse, Not Focal, Frontal Atrophy Subtype Shows Worse Prognosis in Frontotemporal Dementia Alzheimer's & Dementia. 12: P1111-P1112. DOI: 10.1016/J.Jalz.2016.06.2311  0.337
2016 Lowe VJ, Wiste HJ, Fang P, Senjem ML, Boeve BF, Josephs KA, Murray ME, Kantarci K, Jones DT, Schwarz CG, Knopman DS, Petersen RC, Jack CR, Vemuri P. IC-P-197: Regional TAU-PET Uptake Patterns and Their Association with Braak Staging, Cognition, and Onset of ad-Dementia Alzheimer's & Dementia. 12: P142-P143. DOI: 10.1016/J.Jalz.2016.06.228  0.423
2016 Boeve BF, Jones DT, Lowe VJ, Wiste HJ, Senjem ML, Kantarci K, Knopman DS, Dheel C, Wszolek Z, Rademakers R, Petersen RC, Jack CR. Pet Tau Imaging With Av-1451 In Microtubule Associated Protein Tau (Mapt) Mutation Carriers Relative To Alzheimer’S Disease Dementia And Controls Alzheimers & Dementia. 12: 131. DOI: 10.1016/J.Jalz.2016.06.211  0.359
2016 Wennberg AM, Savica R, Hagen CE, Roberts RO, Knopman DS, Jack CR, Petersen RC, Mielke MM. P3-268: Cerebral Amyloid Deposition is Associated with Poorer Gait in Cognitively Normal Late-Middle Aged Individuals: the Mayo Clinic Study of Aging Alzheimer's & Dementia. 12: P935-P935. DOI: 10.1016/J.Jalz.2016.06.1931  0.394
2016 Power MC, Rawlings A, Sharrett AR, Bandeen-Roche K, Coresh J, Ballantyne CM, Pokharel Y, Penman A, Alonso A, Knopman DS, Mosley T, Gottesman RF. Association Of Baseline Lipids With 20-Year Cognitive Change: The Aric Neurocognitive Study Alzheimers & Dementia. 12: 804. DOI: 10.1016/J.Jalz.2016.06.1627  0.348
2016 Graff-Radford J, Boeve BF, Aakre JA, Savica R, Ferman TJ, Dickson DW, Kremers W, Jones DT, Kantarci K, Knopman DS, Petersen RC. Pathologic Predictors Of Disease Duration In Lewy Body Disease Alzheimers & Dementia. 12: 698. DOI: 10.1016/J.Jalz.2016.06.1369  0.313
2016 Lowe VJ, Senjem ML, Knopman DS, Lundt ES, Gunter JL, Schwarz CG, Jack CR, Petersen RC. Comparison Of [18F]Flutametamol And [11C]Pib In Normal Young, Normal Elderly, And Alzheimer'S Disease Subjects Alzheimers & Dementia. 12. DOI: 10.1016/J.Jalz.2016.06.1011  0.328
2016 Murray ME, Curran GL, Fang P, Josephs KA, Parisi JE, Kantarci K, Boeve BF, Pandey M, Bruinsma TJ, Knopman DS, Jones DT, Petrucelli L, Cook C, Dickson DW, Petersen RC, et al. IC-01-05: Neuropathologic Features of AV1451 TAU Pet Autoradiography in Dementia Alzheimer's & Dementia. 12: P4-P4. DOI: 10.1016/J.Jalz.2016.06.065  0.334
2016 Vemuri P, Lowe VJ, Wiste HJ, Weigand SD, Senjem ML, Knopman DS, Petersen RC, Jack CR. IC-01-01: Predictors of Regional TAU-PET Uptake: Mayo Clinic Study of Aging Alzheimer's & Dementia. 12: P1-P1. DOI: 10.1016/J.Jalz.2016.06.061  0.301
2015 Murray AM, Bell EJ, Tupper DE, Davey CS, Pederson SL, Amiot EM, Miley KM, McPherson L, Heubner BM, Gilbertson DT, Foley RN, Drawz PE, Slinin Y, Rossom RC, Lakshminarayan K, ... ... Knopman DS, et al. The Brain in Kidney Disease (BRINK) Cohort Study: Design and Baseline Cognitive Function. American Journal of Kidney Diseases : the Official Journal of the National Kidney Foundation. PMID 26744128 DOI: 10.1053/J.Ajkd.2015.11.008  0.384
2015 Graff-Radford J, Madhavan M, Vemuri P, Rabinstein AA, Cha RH, Mielke MM, Kantarci K, Lowe V, Senjem ML, Gunter JL, Knopman DS, Petersen RC, Jack CR, Roberts RO. Atrial fibrillation, cognitive impairment, and neuroimaging. Alzheimer's & Dementia : the Journal of the Alzheimer's Association. PMID 26607820 DOI: 10.1016/J.Jalz.2015.08.164  0.424
2015 Mielke MM, Machulda MM, Hagen CE, Christianson TJ, Roberts RO, Knopman DS, Vemuri P, Lowe VJ, Kremers WK, Jack CR, Petersen RC. Influence of amyloid and apolipoprotein E on cognitive performance in a late middle-aged cohort. Alzheimer's & Dementia : the Journal of the Alzheimer's Association. PMID 26602629 DOI: 10.1016/J.Jalz.2015.09.010  0.39
2015 Jack CR, Therneau TM, Wiste HJ, Weigand SD, Knopman DS, Lowe VJ, Mielke MM, Vemuri P, Roberts RO, Machulda MM, Senjem ML, Gunter JL, Rocca WA, Petersen RC. Transition rates between amyloid and neurodegeneration biomarker states and to dementia: a population-based, longitudinal cohort study. The Lancet. Neurology. PMID 26597325 DOI: 10.1016/S1474-4422(15)00323-3  0.355
2015 Petersen RC, Wiste HJ, Weigand SD, Rocca WA, Roberts RO, Mielke MM, Lowe VJ, Knopman DS, Pankratz VS, Machulda MM, Geda YE, Jack CR. Association of Elevated Amyloid Levels With Cognition and Biomarkers in Cognitively Normal People From the Community. Jama Neurology. 1-8. PMID 26595683 DOI: 10.1001/Jamaneurol.2015.3098  0.454
2015 Jones DT, Knopman DS, Gunter JL, Graff-Radford J, Vemuri P, Boeve BF, Petersen RC, Weiner MW, Jack CR. Cascading network failure across the Alzheimer's disease spectrum. Brain : a Journal of Neurology. PMID 26586695 DOI: 10.1093/Brain/Awv338  0.33
2015 Roberts RO, Christianson TJ, Kremers WK, Mielke MM, Machulda MM, Vassilaki M, Alhurani RE, Geda YE, Knopman DS, Petersen RC. Association Between Olfactory Dysfunction and Amnestic Mild Cognitive Impairment and Alzheimer Disease Dementia. Jama Neurology. 1-9. PMID 26569387 DOI: 10.1001/Jamaneurol.2015.2952  0.459
2015 Knopman DS, Beiser A, Machulda MM, Fields J, Roberts RO, Pankratz VS, Aakre J, Cha RH, Rocca WA, Mielke MM, Boeve BF, Devine S, Ivnik RJ, Au R, Auerbach S, et al. Spectrum of cognition short of dementia: Framingham Heart Study and Mayo Clinic Study of Aging. Neurology. 85: 1712-21. PMID 26453643 DOI: 10.1212/Wnl.0000000000002100  0.433
2015 Roberts RO, Aakre JA, Cha RH, Kremers WK, Mielke MM, Velgos SN, Geda YE, Knopman DS, Petersen RC. Association of Pancreatic Polypeptide with Mild Cognitive Impairment Varies by APOE ε4 Allele. Frontiers in Aging Neuroscience. 7: 172. PMID 26441635 DOI: 10.3389/Fnagi.2015.00172  0.364
2015 Knopman DS, Jack CR, Lundt ES, Wiste HJ, Weigand SD, Vemuri P, Lowe VJ, Kantarci K, Gunter JL, Senjem ML, Mielke MM, Machulda MM, Roberts RO, Boeve BF, Jones DT, et al. Role of β-Amyloidosis and Neurodegeneration in Subsequent Imaging Changes in Mild Cognitive Impairment. Jama Neurology. 1-9. PMID 26437123 DOI: 10.1001/Jamaneurol.2015.2323  0.411
2015 Jack CR, Wiste HJ, Weigand SD, Knopman DS, Mielke MM, Vemuri P, Lowe V, Senjem ML, Gunter JL, Reyes D, Machulda MM, Roberts R, Petersen RC. Different definitions of neurodegeneration produce similar amyloid/neurodegeneration biomarker group findings. Brain : a Journal of Neurology. PMID 26428666 DOI: 10.1093/Brain/Awv283  0.331
2015 Vemuri P, Knopman DS. The role of cerebrovascular disease when there is concomitant Alzheimer disease. Biochimica Et Biophysica Acta. PMID 26408957 DOI: 10.1016/J.Bbadis.2015.09.013  0.388
2015 Zhao Q, Roberts RO, Ding D, Cha R, Guo Q, Meng H, Luo J, Machulda MM, Shane Pankratz V, Wang B, Christianson TJ, Aakre JA, Knopman DS, Boeve BF, Hong Z, et al. Diabetes is Associated with Worse Executive Function in Both Eastern and Western Populations: Shanghai Aging Study and Mayo Clinic Study of Aging. Journal of Alzheimer's Disease : Jad. 47: 167-76. PMID 26402765 DOI: 10.3233/Jad-150073  0.327
2015 Gendron TF, van Blitterswijk M, Bieniek KF, Daughrity LM, Jiang J, Rush BK, Pedraza O, Lucas JA, Murray ME, Desaro P, Robertson A, Overstreet K, Thomas CS, Crook JE, Castanedes-Casey M, ... ... Knopman DS, et al. Cerebellar c9RAN proteins associate with clinical and neuropathological characteristics of C9ORF72 repeat expansion carriers. Acta Neuropathologica. 130: 559-73. PMID 26350237 DOI: 10.1007/S00401-015-1474-4  0.348
2015 Vassilaki M, Aakre JA, Cha RH, Kremers WK, St Sauver JL, Mielke MM, Geda YE, Machulda MM, Knopman DS, Petersen RC, Roberts RO. Multimorbidity and Risk of Mild Cognitive Impairment. Journal of the American Geriatrics Society. 63: 1783-90. PMID 26311270 DOI: 10.1111/Jgs.13612  0.409
2015 Knopman DS. Is dominantly inherited Alzheimer disease a clone of sporadic Alzheimer disease? Neurology. 85: 750-751. PMID 26245927 DOI: 10.1212/Wnl.0000000000001897  0.392
2015 Gottesman RF, Fornage M, Knopman DS, Mosley TH. Brain Aging in African-Americans: The Atherosclerosis Risk in Communities (ARIC) Experience. Current Alzheimer Research. 12: 607-13. PMID 26239037 DOI: 10.2174/1567205012666150701102445  0.357
2015 Gungor I, Sarro L, Graff-Radford J, Zuk SM, Tosakulwong N, Przybelski SA, Lesnick T, Boeve BF, Ferman TJ, Smith GE, Knopman DS, Filippi M, Petersen RC, Jack CR, Kantarci K. Frequency and topography of cerebral microbleeds in dementia with Lewy bodies compared to Alzheimer's disease. Parkinsonism & Related Disorders. PMID 26205074 DOI: 10.1016/J.Parkreldis.2015.07.008  0.398
2015 Nedelska Z, Schwarz CG, Boeve BF, Lowe VJ, Reid RI, Przybelski SA, Lesnick TG, Gunter JL, Senjem ML, Ferman TJ, Smith GE, Geda YE, Knopman DS, Petersen RC, Jack CR, et al. White matter integrity in dementia with Lewy bodies: a voxel-based analysis of diffusion tensor imaging. Neurobiology of Aging. 36: 2010-7. PMID 25863527 DOI: 10.1016/J.Neurobiolaging.2015.03.007  0.418
2015 Mielke MM, Machulda MM, Hagen CE, Edwards KK, Roberts RO, Pankratz VS, Knopman DS, Jack CR, Petersen RC. Performance of the CogState computerized battery in the Mayo Clinic Study on Aging. Alzheimer's & Dementia : the Journal of the Alzheimer's Association. PMID 25858683 DOI: 10.1016/J.Jalz.2015.01.008  0.386
2015 Roberts RO, Cha RH, Mielke MM, Geda YE, Boeve BF, Machulda MM, Knopman DS, Petersen RC. Risk and protective factors for cognitive impairment in persons aged 85 years and older. Neurology. 84: 1854-61. PMID 25854867 DOI: 10.1212/Wnl.0000000000001537  0.403
2015 Deal JA, Sharrett AR, Albert MS, Coresh J, Mosley TH, Knopman D, Wruck LM, Lin FR. Hearing impairment and cognitive decline: a pilot study conducted within the atherosclerosis risk in communities neurocognitive study. American Journal of Epidemiology. 181: 680-90. PMID 25841870 DOI: 10.1093/Aje/Kwu333  0.39
2015 Murray ME, Lowe VJ, Graff-Radford NR, Liesinger AM, Cannon A, Przybelski SA, Rawal B, Parisi JE, Petersen RC, Kantarci K, Ross OA, Duara R, Knopman DS, Jack CR, Dickson DW. Clinicopathologic and 11C-Pittsburgh compound B implications of Thal amyloid phase across the Alzheimer's disease spectrum. Brain : a Journal of Neurology. 138: 1370-81. PMID 25805643 DOI: 10.1093/Brain/Awv050  0.388
2015 Vemuri P, Senjem ML, Gunter JL, Lundt ES, Tosakulwong N, Weigand SD, Borowski BJ, Bernstein MA, Zuk SM, Lowe VJ, Knopman DS, Petersen RC, Fox NC, Thompson PM, Weiner MW, et al. Accelerated vs. unaccelerated serial MRI based TBM-SyN measurements for clinical trials in Alzheimer's disease. Neuroimage. 113: 61-9. PMID 25797830 DOI: 10.1016/J.Neuroimage.2015.03.026  0.391
2015 Pankratz VS, Roberts RO, Mielke MM, Knopman DS, Jack CR, Geda YE, Rocca WA, Petersen RC. Predicting the risk of mild cognitive impairment in the Mayo Clinic Study of Aging. Neurology. 84: 1433-42. PMID 25788555 DOI: 10.1212/Wnl.0000000000001437  0.444
2015 Jellinger KA, Alafuzoff I, Attems J, Beach TG, Cairns NJ, Crary JF, Dickson DW, Hof PR, Hyman BT, Jack CR, Jicha GA, Knopman DS, Kovacs GG, Mackenzie IR, Masliah E, et al. PART, a distinct tauopathy, different from classical sporadic Alzheimer disease. Acta Neuropathologica. 129: 757-62. PMID 25778618 DOI: 10.1007/S00401-015-1407-2  0.449
2015 Jack CR, Wiste HJ, Weigand SD, Knopman DS, Vemuri P, Mielke MM, Lowe V, Senjem ML, Gunter JL, Machulda MM, Gregg BE, Pankratz VS, Rocca WA, Petersen RC. Age, Sex, and APOE ε4 Effects on Memory, Brain Structure, and β-Amyloid Across the Adult Life Span. Jama Neurology. 72: 511-9. PMID 25775353 DOI: 10.1001/Jamaneurol.2014.4821  0.409
2015 Brown CH, Sharrett AR, Coresh J, Schneider AL, Alonso A, Knopman DS, Mosley TH, Gottesman RF. Association of hospitalization with long-term cognitive and brain MRI changes in the ARIC cohort. Neurology. 84: 1443-53. PMID 25762715 DOI: 10.1212/Wnl.0000000000001439  0.38
2015 Vassilaki M, Cha RH, Aakre JA, Therneau TM, Geda YE, Mielke MM, Knopman DS, Petersen RC, Roberts RO. Mortality in mild cognitive impairment varies by subtype, sex, and lifestyle factors: the Mayo Clinic Study of Aging. Journal of Alzheimer's Disease : Jad. 45: 1237-45. PMID 25697699 DOI: 10.3233/Jad-143078  0.418
2015 Whitwell JL, Boeve BF, Weigand SD, Senjem ML, Gunter JL, Baker MC, DeJesus-Hernandez M, Knopman DS, Wszolek ZK, Petersen RC, Rademakers R, Jack CR, Josephs KA. Brain atrophy over time in genetic and sporadic frontotemporal dementia: a study of 198 serial magnetic resonance images. European Journal of Neurology : the Official Journal of the European Federation of Neurological Societies. 22: 745-52. PMID 25683866 DOI: 10.1111/Ene.12675  0.348
2015 Chauhan G, Adams HH, Bis JC, Weinstein G, Yu L, Töglhofer AM, Smith AV, van der Lee SJ, Gottesman RF, Thomson R, Wang J, Yang Q, Niessen WJ, Lopez OL, Becker JT, ... ... Knopman DS, et al. Association of Alzheimer's disease GWAS loci with MRI markers of brain aging. Neurobiology of Aging. 36: 1765.e7-16. PMID 25670335 DOI: 10.1016/J.Neurobiolaging.2014.12.028  0.404
2015 Verhaaren BF, Debette S, Bis JC, Smith JA, Ikram MK, Adams HH, Beecham AH, Rajan KB, Lopez LM, Barral S, van Buchem MA, van der Grond J, Smith AV, Hegenscheid K, Aggarwal NT, ... ... Knopman DS, et al. Multiethnic genome-wide association study of cerebral white matter hyperintensities on MRI. Circulation. Cardiovascular Genetics. 8: 398-409. PMID 25663218 DOI: 10.1161/Circgenetics.114.000858  0.307
2015 Pink A, Stokin GB, Bartley MM, Roberts RO, Sochor O, Machulda MM, Krell-Roesch J, Knopman DS, Acosta JI, Christianson TJ, Pankratz VS, Mielke MM, Petersen RC, Geda YE. Neuropsychiatric symptoms, APOE ε4, and the risk of incident dementia: a population-based study. Neurology. 84: 935-43. PMID 25653291 DOI: 10.1212/Wnl.0000000000001307  0.419
2015 Davies G, Armstrong N, Bis JC, Bressler J, Chouraki V, Giddaluru S, Hofer E, Ibrahim-Verbaas CA, Kirin M, Lahti J, van der Lee SJ, Le Hellard S, Liu T, Marioni RE, Oldmeadow C, ... ... Knopman DS, et al. Genetic contributions to variation in general cognitive function: a meta-analysis of genome-wide association studies in the CHARGE consortium (N=53949). Molecular Psychiatry. 20: 183-92. PMID 25644384 DOI: 10.1038/Mp.2014.188  0.357
2015 Vemuri P, Lesnick TG, Przybelski SA, Knopman DS, Preboske GM, Kantarci K, Raman MR, Machulda MM, Mielke MM, Lowe VJ, Senjem ML, Gunter JL, Rocca WA, Roberts RO, Petersen RC, et al. Vascular and amyloid pathologies are independent predictors of cognitive decline in normal elderly. Brain : a Journal of Neurology. 138: 761-71. PMID 25595145 DOI: 10.1093/Brain/Awu393  0.497
2015 Knopman DS, Griswold ME, Lirette ST, Gottesman RF, Kantarci K, Sharrett AR, Jack CR, Graff-Radford J, Schneider AL, Windham BG, Coker LH, Albert MS, Mosley TH. Vascular imaging abnormalities and cognition: mediation by cortical volume in nondemented individuals: atherosclerosis risk in communities-neurocognitive study. Stroke; a Journal of Cerebral Circulation. 46: 433-40. PMID 25563642 DOI: 10.1161/Strokeaha.114.007847  0.377
2015 Snyder HM, Corriveau RA, Craft S, Faber JE, Greenberg SM, Knopman D, Lamb BT, Montine TJ, Nedergaard M, Schaffer CB, Schneider JA, Wellington C, Wilcock DM, Zipfel GJ, Zlokovic B, et al. Vascular contributions to cognitive impairment and dementia including Alzheimer's disease. Alzheimer's & Dementia : the Journal of the Alzheimer's Association. 11: 710-717. PMID 25510382 DOI: 10.1016/J.Jalz.2014.10.008  0.436
2015 Nedelska Z, Ferman TJ, Boeve BF, Przybelski SA, Lesnick TG, Murray ME, Gunter JL, Senjem ML, Vemuri P, Smith GE, Geda YE, Graff-Radford J, Knopman DS, Petersen RC, Parisi JE, et al. Pattern of brain atrophy rates in autopsy-confirmed dementia with Lewy bodies. Neurobiology of Aging. 36: 452-61. PMID 25128280 DOI: 10.1016/J.Neurobiolaging.2014.07.005  0.437
2015 Zhang B, Ferman TJ, Boeve BF, Smith GE, Maroney-Smith M, Spychalla AJ, Knopman DS, Jack CR, Petersen RC, Kantarci K. MRS in mild cognitive impairment: early differentiation of dementia with Lewy bodies and Alzheimer's disease. Journal of Neuroimaging : Official Journal of the American Society of Neuroimaging. 25: 269-74. PMID 25039916 DOI: 10.1111/Jon.12138  0.508
2015 Schneider AL, Sharrett AR, Gottesman RF, Coresh J, Coker L, Wruck L, Selnes OA, Deal J, Knopman D, Mosley TH. Normative data for 8 neuropsychological tests in older blacks and whites from the atherosclerosis risk in communities (ARIC) study. Alzheimer Disease and Associated Disorders. 29: 32-44. PMID 24759546 DOI: 10.1097/Wad.0000000000000042  0.389
2015 Radford JG, Boeve B, Lesnick TG, Przybelski SA, Ferman TJ, Jones DT, Senjem ML, Gunter JL, Knopman DS, Jack CR, Petersen RC, Kantarci K. Predicting survival in dementia with lewy bodies: The importance of hippocampal volume Alzheimers & Dementia. 11: 875. DOI: 10.1016/J.Jalz.2015.08.074  0.303
2015 Vemuri P, Lesnick TG, Przybelski SA, Machulda MM, Knopman DS, Mielke M, Roberts R, Lowe VJ, Rocca W, Geda YE, Petersen RC, Jack CR. F5-01-03: Better intellectual lifestyle to keep cognitive impairment away Alzheimer's & Dementia. 11: P303-P304. DOI: 10.1016/J.Jalz.2015.07.425  0.347
2015 Krell-Roesch J, Pink A, Roberts RO, Mielke MM, Christianson TJ, Knopman DS, Stokin GB, Petersen RC, Geda YE. O3-11-06: Caloric intake and the risk of mild cognitive impairment: A population-based cohort study Alzheimer's & Dementia. 11: P246-P246. DOI: 10.1016/J.Jalz.2015.07.302  0.354
2015 Sarro L, Gungor I, Radford JG, Zuk SM, Tosakulwong N, Przybelski SA, Boeve B, Ferman TJ, Smith GE, Knopman DS, Filippi M, Petersen RC, Jack CR, Kantarci K. Frequency and distribution of cerebral microbleeds in dementia with lewy bodies Alzheimers & Dementia. 11: 199. DOI: 10.1016/J.Jalz.2015.07.188  0.3
2015 Mielke MM, Machulda MM, Hagen CE, Christianson TJ, Roberts RO, Knopman DS, Vemuri P, Lowe VJ, Jack CR, Petersen RC. P2-167: Influence of amyloid and APOE genotype on cognitive performance in a middle-aged cohort Alzheimer's & Dementia. 11: P553-P553. DOI: 10.1016/J.Jalz.2015.06.706  0.402
2015 Boeve AR, Ferman TJ, Aakre JA, Louis EKS, Silber MH, Machulda MM, Fields JA, Graff-Radford N, Mielke MM, Geda YE, Jones DT, Radford JG, Knopman DS, Petersen RC, Boeve B. Excessive daytime sleepiness is comparable in behavioral variant frontotemporal dementia and Alzheimer's disease dementia but greater in dementia with lewy bodies Alzheimers & Dementia. 11: 392. DOI: 10.1016/J.Jalz.2015.06.329  0.415
2015 Allen M, Wang X, Serie D, Strickland SL, Burgess JD, Nguyen T, Malphrus KG, Lincoln S, Carrasquillo MM, Crook J, Schellenberg GD, Knopman DS, Lowe VJ, Jack CR, Younkin SG, et al. Exploiting blood transcriptome for gene and pathway identification in Alzheimer's disease Alzheimers & Dementia. 11: 357. DOI: 10.1016/J.Jalz.2015.06.245  0.314
2015 Murray A, Tupper D, Savik S, Amiot E, Knopman DS. Risk factors for prevalent cognitive impairment in chronic kidney disease: The brain in kidney disease (BRINK) study Alzheimers & Dementia. 11. DOI: 10.1016/J.Jalz.2015.06.1828  0.353
2015 Kantarci K, Lesnick TG, Przybelski SA, Ferman TJ, Boeve B, Smith GE, Knopman DS, Jack CR, Petersen RC. Hippocampal volumes predict risk of dementia with lewy bodies in mild cognitive impairment Alzheimers & Dementia. 11. DOI: 10.1016/J.Jalz.2015.06.011  0.407
2014 Ferman TJ, Smith GE, Dickson DW, Graff-Radford NR, Lin SC, Wszolek Z, Van Gerpen JA, Uitti R, Knopman DS, Petersen RC, Parisi JE, Silber MH, Boeve BF. Abnormal daytime sleepiness in dementia with Lewy bodies compared to Alzheimer's disease using the Multiple Sleep Latency Test. Alzheimer's Research & Therapy. 6: 76. PMID 25512763 DOI: 10.1186/S13195-014-0076-Z  0.386
2014 Murray ME, Przybelski SA, Lesnick TG, Liesinger AM, Spychalla A, Zhang B, Gunter JL, Parisi JE, Boeve BF, Knopman DS, Petersen RC, Jack CR, Dickson DW, Kantarci K. Early Alzheimer's disease neuropathology detected by proton MR spectroscopy. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 34: 16247-55. PMID 25471565 DOI: 10.1523/Jneurosci.2027-14.2014  0.398
2014 Mielke MM, Weigand SD, Wiste HJ, Vemuri P, Machulda MM, Knopman DS, Lowe V, Roberts RO, Kantarci K, Rocca WA, Jack CR, Petersen RC. Independent comparison of CogState computerized testing and a standard cognitive battery with neuroimaging. Alzheimer's & Dementia : the Journal of the Alzheimer's Association. 10: 779-89. PMID 25458308 DOI: 10.1016/J.Jalz.2014.09.001  0.427
2014 Mayeda ER, Haan MN, Neuhaus J, Yaffe K, Knopman DS, Sharrett AR, Griswold ME, Mosley TH. Type 2 diabetes and cognitive decline over 14 years in middle-aged African Americans and whites: the ARIC Brain MRI Study. Neuroepidemiology. 43: 220-7. PMID 25402639 DOI: 10.1159/000366506  0.375
2014 Crary JF, Trojanowski JQ, Schneider JA, Abisambra JF, Abner EL, Alafuzoff I, Arnold SE, Attems J, Beach TG, Bigio EH, Cairns NJ, Dickson DW, Gearing M, Grinberg LT, Hof PR, ... ... Knopman DS, et al. Primary age-related tauopathy (PART): a common pathology associated with human aging. Acta Neuropathologica. 128: 755-66. PMID 25348064 DOI: 10.1007/S00401-014-1349-0  0.5
2014 Kantarci K, Schwarz CG, Reid RI, Przybelski SA, Lesnick TG, Zuk SM, Senjem ML, Gunter JL, Lowe V, Machulda MM, Knopman DS, Petersen RC, Jack CR. White matter integrity determined with diffusion tensor imaging in older adults without dementia: influence of amyloid load and neurodegeneration. Jama Neurology. 71: 1547-54. PMID 25347157 DOI: 10.1001/Jamaneurol.2014.1482  0.37
2014 Fargo KN, Aisen P, Albert M, Au R, Corrada MM, DeKosky S, Drachman D, Fillit H, Gitlin L, Haas M, Herrup K, Kawas C, Khachaturian AS, Khachaturian ZS, ... ... Knopman D, et al. 2014 Report on the Milestones for the US National Plan to Address Alzheimer's Disease. Alzheimer's & Dementia : the Journal of the Alzheimer's Association. 10: S430-52. PMID 25341459 DOI: 10.1016/J.Jalz.2014.08.103  0.342
2014 Knopman DS, Petersen RC. Mild cognitive impairment and mild dementia: a clinical perspective. Mayo Clinic Proceedings. 89: 1452-9. PMID 25282431 DOI: 10.1016/j.mayocp.2014.06.019  0.368
2014 Jack CR, Wiste HJ, Weigand SD, Rocca WA, Knopman DS, Mielke MM, Lowe VJ, Senjem ML, Gunter JL, Preboske GM, Pankratz VS, Vemuri P, Petersen RC. Age-specific population frequencies of cerebral β-amyloidosis and neurodegeneration among people with normal cognitive function aged 50-89 years: a cross-sectional study. The Lancet. Neurology. 13: 997-1005. PMID 25201514 DOI: 10.1016/S1474-4422(14)70194-2  0.427
2014 Dearborn JL, Knopman D, Sharrett AR, Schneider AL, Jack CR, Coker LH, Alonso A, Selvin E, Mosley TH, Wagenknecht LE, Windham BG, Gottesman RF. The metabolic syndrome and cognitive decline in the Atherosclerosis Risk in Communities study (ARIC). Dementia and Geriatric Cognitive Disorders. 38: 337-46. PMID 25171458 DOI: 10.1159/000362265  0.32
2014 Gottesman RF, Schneider AL, Albert M, Alonso A, Bandeen-Roche K, Coker L, Coresh J, Knopman D, Power MC, Rawlings A, Sharrett AR, Wruck LM, Mosley TH. Midlife hypertension and 20-year cognitive change: the atherosclerosis risk in communities neurocognitive study. Jama Neurology. 71: 1218-27. PMID 25090106 DOI: 10.1001/Jamaneurol.2014.1646  0.399
2014 Montine TJ, Koroshetz WJ, Babcock D, Dickson DW, Galpern WR, Glymour MM, Greenberg SM, Hutton ML, Knopman DS, Kuzmichev AN, Manly JJ, Marder KS, Miller BL, Phelps CH, Seeley WW, et al. Recommendations of the Alzheimer's disease-related dementias conference. Neurology. 83: 851-60. PMID 25080517 DOI: 10.1212/Wnl.0000000000000733  0.416
2014 Graff-Radford J, Murray ME, Lowe VJ, Boeve BF, Ferman TJ, Przybelski SA, Lesnick TG, Senjem ML, Gunter JL, Smith GE, Knopman DS, Jack CR, Dickson DW, Petersen RC, Kantarci K. Dementia with Lewy bodies: basis of cingulate island sign. Neurology. 83: 801-9. PMID 25056580 DOI: 10.1212/Wnl.0000000000000734  0.377
2014 Vemuri P, Lesnick TG, Przybelski SA, Machulda M, Knopman DS, Mielke MM, Roberts RO, Geda YE, Rocca WA, Petersen RC, Jack CR. Association of lifetime intellectual enrichment with cognitive decline in the older population. Jama Neurology. 71: 1017-24. PMID 25054282 DOI: 10.1001/Jamaneurol.2014.963  0.385
2014 Russo G, Russo MJ, Buyatti D, Chrem P, Bagnati P, Fernández Suarez M, Campos J, Cohen G, Amengual A, Allegri RF, Knopman DS. Utility of the Spanish version of the FTLD-modified CDR in the diagnosis and staging in frontotemporal lobar degeneration. Journal of the Neurological Sciences. 344: 63-8. PMID 25015844 DOI: 10.1016/J.Jns.2014.06.024  0.403
2014 Ferrari R, Hernandez DG, Nalls MA, Rohrer JD, Ramasamy A, Kwok JB, Dobson-Stone C, Brooks WS, Schofield PR, Halliday GM, Hodges JR, Piguet O, Bartley L, Thompson E, Haan E, ... ... Knopman D, et al. Frontotemporal dementia and its subtypes: a genome-wide association study. The Lancet. Neurology. 13: 686-99. PMID 24943344 DOI: 10.1016/S1474-4422(14)70065-1  0.328
2014 Knopman DS, Roberts RO, Pankratz VS, Cha RH, Rocca WA, Mielke MM, Boeve BF, Tangalos EG, Ivnik RJ, Geda YE, Petersen RC. Incidence of dementia among participants and nonparticipants in a longitudinal study of cognitive aging. American Journal of Epidemiology. 180: 414-23. PMID 24859276 DOI: 10.1093/Aje/Kwu103  0.4
2014 Raman MR, Preboske GM, Przybelski SA, Gunter JL, Senjem ML, Vemuri P, Murphy MC, Murray ME, Boeve BF, Knopman DS, Petersen RC, Parisi JE, Dickson DW, Jack CR, Kantarci K. Antemortem MRI findings associated with microinfarcts at autopsy. Neurology. 82: 1951-8. PMID 24793188 DOI: 10.1212/Wnl.0000000000000471  0.399
2014 Jung Y, Dickson DW, Murray ME, Whitwell JL, Knopman DS, Boeve BF, Jack CR, Parisi JE, Petersen RC, Josephs KA. TDP-43 in Alzheimer's disease is not associated with clinical FTLD or Parkinsonism. Journal of Neurology. 261: 1344-8. PMID 24760339 DOI: 10.1007/S00415-014-7352-5  0.439
2014 Knopman DS. β-Amyloidosis and neurodegeneration in Alzheimer disease: who's on first? Neurology. 82: 1756-7. PMID 24748669 DOI: 10.1212/Wnl.0000000000000438  0.396
2014 Jack CR, Wiste HJ, Knopman DS, Vemuri P, Mielke MM, Weigand SD, Senjem ML, Gunter JL, Lowe V, Gregg BE, Pankratz VS, Petersen RC. Rates of β-amyloid accumulation are independent of hippocampal neurodegeneration. Neurology. 82: 1605-12. PMID 24706010 DOI: 10.1212/Wnl.0000000000000386  0.375
2014 Knopman DS, Jack CR, Wiste HJ, Lundt ES, Weigand SD, Vemuri P, Lowe VJ, Kantarci K, Gunter JL, Senjem ML, Mielke MM, Roberts RO, Boeve BF, Petersen RC. 18F-fluorodeoxyglucose positron emission tomography, aging, and apolipoprotein E genotype in cognitively normal persons. Neurobiology of Aging. 35: 2096-106. PMID 24702820 DOI: 10.1016/J.Neurobiolaging.2014.03.006  0.428
2014 Geda YE, Roberts RO, Mielke MM, Knopman DS, Christianson TJ, Pankratz VS, Boeve BF, Sochor O, Tangalos EG, Petersen RC, Rocca WA. Baseline neuropsychiatric symptoms and the risk of incident mild cognitive impairment: a population-based study. The American Journal of Psychiatry. 171: 572-81. PMID 24700290 DOI: 10.1176/Appi.Ajp.2014.13060821  0.429
2014 Josephs KA, Whitwell JL, Weigand SD, Murray ME, Tosakulwong N, Liesinger AM, Petrucelli L, Senjem ML, Knopman DS, Boeve BF, Ivnik RJ, Smith GE, Jack CR, Parisi JE, Petersen RC, et al. TDP-43 is a key player in the clinical features associated with Alzheimer's disease. Acta Neuropathologica. 127: 811-24. PMID 24659241 DOI: 10.1007/S00401-014-1269-Z  0.523
2014 Roberts RO, Knopman DS, Przybelski SA, Mielke MM, Kantarci K, Preboske GM, Senjem ML, Pankratz VS, Geda YE, Boeve BF, Ivnik RJ, Rocca WA, Petersen RC, Jack CR. Association of type 2 diabetes with brain atrophy and cognitive impairment. Neurology. 82: 1132-41. PMID 24647028 DOI: 10.1212/Wnl.0000000000000269  0.404
2014 Gottesman RF, Rawlings AM, Sharrett AR, Albert M, Alonso A, Bandeen-Roche K, Coker LH, Coresh J, Couper DJ, Griswold ME, Heiss G, Knopman DS, Patel MD, Penman AD, Power MC, et al. Impact of differential attrition on the association of education with cognitive change over 20 years of follow-up: the ARIC neurocognitive study. American Journal of Epidemiology. 179: 956-66. PMID 24627572 DOI: 10.1093/Aje/Kwu020  0.419
2014 Hanff TC, Sharrett AR, Mosley TH, Shibata D, Knopman DS, Klein R, Klein BE, Gottesman RF. Retinal microvascular abnormalities predict progression of brain microvascular disease: an atherosclerosis risk in communities magnetic resonance imaging study. Stroke; a Journal of Cerebral Circulation. 45: 1012-7. PMID 24549866 DOI: 10.1161/Strokeaha.113.004166  0.347
2014 Graff-Radford J, Boeve BF, Murray ME, Ferman TJ, Tosakulwong N, Lesnick TG, Maroney-Smith M, Senjem ML, Gunter J, Smith GE, Knopman DS, Jack CR, Dickson DW, Petersen RC, Kantarci K. Regional proton magnetic resonance spectroscopy patterns in dementia with Lewy bodies. Neurobiology of Aging. 35: 1483-90. PMID 24468473 DOI: 10.1016/J.Neurobiolaging.2014.01.001  0.441
2014 Parsaik AK, Singh B, Roberts RO, Pankratz S, Edwards KK, Geda YE, Gharib H, Boeve BF, Knopman DS, Petersen RC. Hypothyroidism and risk of mild cognitive impairment in elderly persons: a population-based study. Jama Neurology. 71: 201-7. PMID 24378475 DOI: 10.1001/Jamaneurol.2013.5402  0.444
2014 Mielke MM, Savica R, Wiste HJ, Weigand SD, Vemuri P, Knopman DS, Lowe VJ, Roberts RO, Machulda MM, Geda YE, Petersen RC, Jack CR. Head trauma and in vivo measures of amyloid and neurodegeneration in a population-based study. Neurology. 82: 70-6. PMID 24371306 DOI: 10.1212/01.Wnl.0000438229.56094.54  0.44
2014 Roberts RO, Knopman DS, Mielke MM, Cha RH, Pankratz VS, Christianson TJ, Geda YE, Boeve BF, Ivnik RJ, Tangalos EG, Rocca WA, Petersen RC. Higher risk of progression to dementia in mild cognitive impairment cases who revert to normal. Neurology. 82: 317-25. PMID 24353333 DOI: 10.1212/Wnl.0000000000000055  0.473
2014 Singh B, Parsaik AK, Mielke MM, Erwin PJ, Knopman DS, Petersen RC, Roberts RO. Association of mediterranean diet with mild cognitive impairment and Alzheimer's disease: a systematic review and meta-analysis. Journal of Alzheimer's Disease : Jad. 39: 271-82. PMID 24164735 DOI: 10.3233/Jad-130830  0.422
2014 Roberts RO, Knopman DS, Geda YE, Cha RH, Pankratz VS, Baertlein L, Boeve BF, Tangalos EG, Ivnik RJ, Mielke MM, Petersen RC. Association of diabetes with amnestic and nonamnestic mild cognitive impairment. Alzheimer's & Dementia : the Journal of the Alzheimer's Association. 10: 18-26. PMID 23562428 DOI: 10.1016/J.Jalz.2013.01.001  0.459
2014 Caselli RJ, Locke DE, Dueck AC, Knopman DS, Woodruff BK, Hoffman-Snyder C, Rademakers R, Fleisher AS, Reiman EM. The neuropsychology of normal aging and preclinical Alzheimer's disease. Alzheimer's & Dementia : the Journal of the Alzheimer's Association. 10: 84-92. PMID 23541188 DOI: 10.1016/J.Jalz.2013.01.004  0.456
2014 Adeli A, Savica R, Lowe VJ, Vemuri P, Knopman DS, Dejesus-Hernandez M, Rademakers R, Fields JA, Crum BA, Jack CR, Petersen RC, Boeve BF. The GGGGCC repeat expansion in C9ORF72 in a case with discordant clinical and FDG-PET findings: PET trumps syndrome. Neurocase. 20: 110-20. PMID 23199140 DOI: 10.1080/13554794.2012.732090  0.381
2014 Josephs K, Whitwell JL, Weigand S, Murray ME, Tosakulwong N, Liesinger A, Petrucelli L, Senjem M, Knopman DS, Boeve BF, Ivnik R, Smith G, Jack C, Parisi J, Petersen RC, et al. TDP-43 AMPLIFIES MEMORY LOSS AND HIPPOCAMPAL ATROPHY IN ALZHEIMER'S DISEASE Alzheimer's & Dementia. 10: P279-P280. DOI: 10.1016/J.Jalz.2014.07.149  0.317
2014 Krell-Roesch J, Acosta JI, Stokin GB, Bartley MM, Roberts RO, Knopman DS, Christianson TJ, Pankratz VS, Petersen RC, Geda YE. P2-149: PHYSICAL EXERCISE IN MID-LIFE VERSUS LATE LIFE MAY HAVE A DIFFERENTIAL IMPACT ON THE OUTCOME OF INCIDENT MILD COGNITIVE IMPAIRMENT: THE MAYO CLINIC STUDY OF AGING Alzheimer's & Dementia. 10: P526-P526. DOI: 10.1016/J.Jalz.2014.05.824  0.335
2014 Knopman DS, Vemuri P, Jack C, Heubner B, Zuk S, Thostenson K, Lundt E, Murray AM. P2-079: ALZHEIMER'S AND VASCULAR DISEASE-SPECIFIC STRUCTURAL BRAIN CHANGES IN CHRONIC KIDNEY DISEASE PATIENTS Alzheimer's & Dementia. 10: P498-P499. DOI: 10.1016/J.Jalz.2014.05.753  0.334
2014 Boeve A, Mielke MM, Geda Y, Roberts RO, Ivnik R, Machulda MM, Fields JA, Pankratz V, Boeve BF, Knopman DS, Petersen R. P1-323: SLEEP-RELATED FEATURES AND PERFORMANCE ON A COMPUTERIZED COGNITIVE BATTERY: THE MAYO CLINIC STUDY OF AGING Alzheimer's & Dementia. 10: P430-P430. DOI: 10.1016/J.Jalz.2014.05.564  0.333
2014 Cerhan LP, Acosta JI, Krell-Roesch J, Roberts RO, Machulda MM, Knopman DS, Christianson TJ, Pankratz VS, Stokin GB, Petersen RC, Geda YE. Empirical Investigation Of Functional Activity In Normal Aging And Mild Cognitive Impairment: The Mayo Clinic Study Of Aging Alzheimers & Dementia. 10: 379. DOI: 10.1016/J.Jalz.2014.05.447  0.373
2014 Mielke MM, Hagen C, Roberts RO, Vemuri P, Machulda MM, Christianson T, Pankratz VS, Knopman DS, Lowe VJ, Jack C, Petersen R. P4-089: SELF- AND INFORMANT-RATED DAILY FUNCTION IS ASSOCIATED WITH AMYLOID AND NEURODEGENERATIVE IMAGING IN COGNITIVELY NORMAL INDIVIDUALS Alzheimer's & Dementia. 10: P816-P816. DOI: 10.1016/J.Jalz.2014.05.1604  0.362
2014 Jones DT, Gunter J, Wiste H, Graff-Radford J, Machulda MM, Vemuri P, Boeve BF, Knopman DS, Petersen RC, Jack C. Impaired Segregation Of The Ventral Default Mode Network In Alzheimer'S Disease Alzheimers & Dementia. 10: 390. DOI: 10.1016/J.Jalz.2014.05.147  0.332
2014 Raman M, Reichard R, Schwarz CG, Senjem M, Przybelski S, Gunter J, Vemuri P, Murray ME, Boeve BF, Knopman DS, Petersen R, Parisi J, Dickson DW, Jack C, Kantarci K. Pathologic Investigation Of Microinfarcts And Association With Gray Matter Atrophy On Antemortem Mri Alzheimers & Dementia. 10: 128. DOI: 10.1016/J.Jalz.2014.05.071  0.304
2014 Boeve BF, Lowe VJ, Kantarci K, Graff-Radford J, Jones DT, Peller P, Mielke MM, Ferman TJ, Silber M, Louis ES, Smith G, Bennett J, Aakre J, Pankratz V, Knopman DS, et al. Datscan Findings In Patients With Rem Sleep Behavior Disorder And/Or Cognitive Impairment Alzheimers & Dementia. 10: 35. DOI: 10.1016/J.Jalz.2014.05.067  0.301
2014 Graff-Radford J, Lowe VJ, Kantarci K, Jones D, Peller P, Przybelski S, Ferman TJ, Smith GE, Bennett J, Pankratz V, Aakre J, Knopman DS, Petersen RC, Boeve BF. Apathy And Reduced Striatal Uptake In Dementia With Lewy Bodies Alzheimers & Dementia. 10: 263. DOI: 10.1016/J.Jalz.2014.04.420  0.33
2014 Chauhan G, Adams HHH, Bis J, Weinstein G, Yu L, Smith A, Lee Svd, Lopez O, Becker JT, Vernooij M, Schmidt H, Srikanth V, Knopman DS, Amouyel P, DeCarli C, et al. Association Of Alzheimer Disease Gwas Loci With Mri-Markers Of Brain Aging Alzheimers & Dementia. 10: 258. DOI: 10.1016/J.Jalz.2014.04.406  0.362
2014 Machulda MM, Hagen C, Mielke MM, Christianson T, Pankratz V, Jack C, Lowe VJ, Ivnik R, Roberts RO, Knopman DS, Petersen RC. O2-10-02: PRACTICE EFFECTS AND LONGITUDINAL COGNITIVE CHANGE AS A FUNCTION OF AMYLOID AND NEURODEGENERATIVE IMAGING BIOMARKERS IN COGNITIVELY NORMAL INDIVIDUALS Alzheimer's & Dementia. 10: P186-P186. DOI: 10.1016/J.Jalz.2014.04.211  0.394
2014 Roberts RO, Cha RH, Geda Y, Pankratz VS, Boeve BF, Mielke MM, Machulda MM, Knopman DS, Petersen RC. Predictors And Protective Factors For Cognitive Impairment In Very Old Cognitively Normal Persons Alzheimers & Dementia. 10: 151. DOI: 10.1016/J.Jalz.2014.04.118  0.376
2014 Jones DT, Weigand S, Przybelski S, Graff-Radford J, Mathew S, Gunter J, Whitwell JL, Knopman DS, Graff-Radford NR, Josephs K, Wszolek Z, Vemuri P, Fields JA, Machulda MM, Ferman TJ, et al. Longitudinal Changes In Brain Mri And Neuropsychological Measures In Asymptomatic And Symptomatic Familial Frontotemporal Lobar Degeneration With Mutations In Mapt Alzheimers & Dementia. 10: 6. DOI: 10.1016/J.Jalz.2014.04.029  0.393
2014 Murray ME, Liesinger AM, Przybelski SA, Gunter JL, Senjem ML, Raman MR, Petersen RC, Dickson DW, Jack CR, Knopman DS. IC-02-04: EARLY, BUT NOT ADVANCED, NEUROFIBRILLARY TANGLE PATHOLOGY OR AMYLOID-B PATHOLOGY SIGNIFICANTLY ASSOCIATES WITH ABNORMAL HIPPOCAMPAL SIZE IN COGNITIVELY NORMAL ELDERLY Alzheimer's & Dementia. 10: P5-P5. DOI: 10.1016/J.Jalz.2014.04.027  0.401
2013 Ferman TJ, Smith GE, Kantarci K, Boeve BF, Pankratz VS, Dickson DW, Graff-Radford NR, Wszolek Z, Van Gerpen J, Uitti R, Pedraza O, Murray ME, Aakre J, Parisi J, Knopman DS, et al. Nonamnestic mild cognitive impairment progresses to dementia with Lewy bodies. Neurology. 81: 2032-8. PMID 24212390 DOI: 10.1212/01.Wnl.0000436942.55281.47  0.48
2013 Whitwell JL, Tosakulwong N, Weigand SD, Senjem ML, Lowe VJ, Gunter JL, Boeve BF, Knopman DS, Dickerson BC, Petersen RC, Jack CR. Does amyloid deposition produce a specific atrophic signature in cognitively normal subjects? Neuroimage. Clinical. 2: 249-57. PMID 24179779 DOI: 10.1016/J.Nicl.2013.01.006  0.463
2013 Jack CR, Wiste HJ, Weigand SD, Knopman DS, Lowe V, Vemuri P, Mielke MM, Jones DT, Senjem ML, Gunter JL, Gregg BE, Pankratz VS, Petersen RC. Amyloid-first and neurodegeneration-first profiles characterize incident amyloid PET positivity. Neurology. 81: 1732-40. PMID 24132377 DOI: 10.1212/01.Wnl.0000435556.21319.E4  0.389
2013 McDade EM, Boot BP, Christianson TJ, Pankratz VS, Boeve BF, Ferman TJ, Bieniek K, Hollman JH, Roberts RO, Mielke MM, Knopman DS, Petersen RC. Subtle gait changes in patients with REM sleep behavior disorder. Movement Disorders : Official Journal of the Movement Disorder Society. 28: 1847-53. PMID 24130124 DOI: 10.1002/Mds.25653  0.305
2013 Murray ME, Ferman TJ, Boeve BF, Przybelski SA, Lesnick TG, Liesinger AM, Senjem ML, Gunter JL, Preboske GM, Lowe VJ, Vemuri P, Dugger BN, Knopman DS, Smith GE, Parisi JE, et al. MRI and pathology of REM sleep behavior disorder in dementia with Lewy bodies. Neurology. 81: 1681-9. PMID 24107861 DOI: 10.1212/01.Wnl.0000435299.57153.F0  0.383
2013 Roberts R, Knopman DS. Classification and epidemiology of MCI. Clinics in Geriatric Medicine. 29: 753-72. PMID 24094295 DOI: 10.1016/J.Cger.2013.07.003  0.461
2013 Machulda MM, Pankratz VS, Christianson TJ, Ivnik RJ, Mielke MM, Roberts RO, Knopman DS, Boeve BF, Petersen RC. Practice effects and longitudinal cognitive change in normal aging vs. incident mild cognitive impairment and dementia in the Mayo Clinic Study of Aging. The Clinical Neuropsychologist. 27: 1247-64. PMID 24041121 DOI: 10.1016/J.Jalz.2013.05.1632  0.458
2013 van Blitterswijk M, DeJesus-Hernandez M, Niemantsverdriet E, Murray ME, Heckman MG, Diehl NN, Brown PH, Baker MC, Finch NA, Bauer PO, Serrano G, Beach TG, Josephs KA, Knopman DS, Petersen RC, et al. Association between repeat sizes and clinical and pathological characteristics in carriers of C9ORF72 repeat expansions (Xpansize-72): a cross-sectional cohort study. The Lancet. Neurology. 12: 978-88. PMID 24011653 DOI: 10.1016/S1474-4422(13)70210-2  0.338
2013 Carrillo MC, Dean RA, Nicolas F, Miller DS, Berman R, Khachaturian Z, Bain LJ, Schindler R, Knopman D. Revisiting the framework of the National Institute on Aging-Alzheimer's Association diagnostic criteria. Alzheimer's & Dementia : the Journal of the Alzheimer's Association. 9: 594-601. PMID 24007744 DOI: 10.1016/J.Jalz.2013.05.1762  0.382
2013 Hamedani AG, Rose KM, Peterlin BL, Mosley TH, Coker LH, Jack CR, Knopman DS, Alonso A, Gottesman RF. Migraine and white matter hyperintensities: the ARIC MRI study. Neurology. 81: 1308-13. PMID 23975874 DOI: 10.1212/Wnl.0B013E3182A8235B  0.309
2013 Boot BP, Orr CF, Ahlskog JE, Ferman TJ, Roberts R, Pankratz VS, Dickson DW, Parisi J, Aakre JA, Geda YE, Knopman DS, Petersen RC, Boeve BF. Risk factors for dementia with Lewy bodies: a case-control study. Neurology. 81: 833-40. PMID 23892702 DOI: 10.1212/Wnl.0B013E3182A2Cbd1  0.353
2013 Rayaprolu S, Mullen B, Baker M, Lynch T, Finger E, Seeley WW, Hatanpaa KJ, Lomen-Hoerth C, Kertesz A, Bigio EH, Lippa C, Josephs KA, Knopman DS, White CL, Caselli R, et al. TREM2 in neurodegeneration: evidence for association of the p.R47H variant with frontotemporal dementia and Parkinson's disease. Molecular Neurodegeneration. 8: 19. PMID 23800361 DOI: 10.1186/1750-1326-8-19  0.394
2013 Knopman DS, Jack CR, Wiste HJ, Weigand SD, Vemuri P, Lowe VJ, Kantarci K, Gunter JL, Senjem ML, Mielke MM, Roberts RO, Boeve BF, Petersen RC. Selective worsening of brain injury biomarker abnormalities in cognitively normal elderly persons with β-amyloidosis. Jama Neurology. 70: 1030-8. PMID 23797806 DOI: 10.1001/Jamaneurol.2013.182  0.461
2013 Kantarci K, Weigand SD, Przybelski SA, Preboske GM, Pankratz VS, Vemuri P, Senjem ML, Murphy MC, Gunter JL, Machulda MM, Ivnik RJ, Roberts RO, Boeve BF, Rocca WA, Knopman DS, et al. MRI and MRS predictors of mild cognitive impairment in a population-based sample. Neurology. 81: 126-33. PMID 23761624 DOI: 10.1212/Wnl.0B013E31829A3329  0.417
2013 Petersen RC, Aisen P, Boeve BF, Geda YE, Ivnik RJ, Knopman DS, Mielke M, Pankratz VS, Roberts R, Rocca WA, Weigand S, Weiner M, Wiste H, Jack CR. Mild cognitive impairment due to Alzheimer disease in the community. Annals of Neurology. 74: 199-208. PMID 23686697 DOI: 10.1002/Ana.23931  0.504
2013 Fugate JE, Moore SA, Knopman DS, Claassen DO, Wijdicks EF, White RD, Rabinstein AA. Cognitive outcomes of patients undergoing therapeutic hypothermia after cardiac arrest. Neurology. 81: 40-5. PMID 23685933 DOI: 10.1212/Wnl.0B013E318297Ee7E  0.329
2013 Lowe VJ, Peller PJ, Weigand SD, Montoya Quintero C, Tosakulwong N, Vemuri P, Senjem ML, Jordan L, Jack CR, Knopman D, Petersen RC. Application of the National Institute on Aging-Alzheimer's Association AD criteria to ADNI. Neurology. 80: 2130-7. PMID 23645596 DOI: 10.1212/Wnl.0B013E318295D6Cf  0.419
2013 Gill DP, Hubbard RA, Koepsell TD, Borrie MJ, Petrella RJ, Knopman DS, Kukull WA. Differences in rate of functional decline across three dementia types. Alzheimer's & Dementia : the Journal of the Alzheimer's Association. 9: S63-71. PMID 23643459 DOI: 10.1016/J.Jalz.2012.10.010  0.434
2013 Graff-Radford J, Rubin MN, Jones DT, Aksamit AJ, Ahlskog JE, Knopman DS, Petersen RC, Boeve BF, Josephs KA. The alien limb phenomenon. Journal of Neurology. 260: 1880-8. PMID 23572346 DOI: 10.1007/S00415-013-6898-Y  0.304
2013 Knopman DS, Roberts RO. Healthy young hearts sharper older minds make. Annals of Neurology. 73: 151-2. PMID 23526555 DOI: 10.1002/Ana.23847  0.424
2013 De Vries R, Ryan KA, Stanczyk A, Appelbaum PS, Damschroder L, Knopman DS, Kim SY. Public's approach to surrogate consent for dementia research: cautious pragmatism. The American Journal of Geriatric Psychiatry : Official Journal of the American Association For Geriatric Psychiatry. 21: 364-72. PMID 23498383 DOI: 10.1016/J.Jagp.2012.11.010  0.3
2013 Knopman DS, Jack CR, Wiste HJ, Weigand SD, Vemuri P, Lowe VJ, Kantarci K, Gunter JL, Senjem ML, Mielke MM, Roberts RO, Boeve BF, Petersen RC. Brain injury biomarkers are not dependent on β-amyloid in normal elderly. Annals of Neurology. 73: 472-80. PMID 23424032 DOI: 10.1002/Ana.23816  0.358
2013 Knopman DS. Alzheimer disease biomarkers and insights into mild cognitive impairment. Neurology. 80: 978-80. PMID 23390186 DOI: 10.1212/Wnl.0B013E31828728Ac  0.466
2013 Roberts RO, Geda YE, Knopman DS, Cha RH, Pankratz VS, Boeve BF, Tangalos EG, Ivnik RJ, Mielke MM, Petersen RC. Cardiac disease associated with increased risk of nonamnestic cognitive impairment: stronger effect on women. Jama Neurology. 70: 374-82. PMID 23358884 DOI: 10.1001/Jamaneurol.2013.607  0.464
2013 Jack CR, Knopman DS, Jagust WJ, Petersen RC, Weiner MW, Aisen PS, Shaw LM, Vemuri P, Wiste HJ, Weigand SD, Lesnick TG, Pankratz VS, Donohue MC, Trojanowski JQ. Tracking pathophysiological processes in Alzheimer's disease: an updated hypothetical model of dynamic biomarkers. The Lancet. Neurology. 12: 207-16. PMID 23332364 DOI: 10.1016/S1474-4422(12)70291-0  0.43
2013 Lu PH, Mendez MF, Lee GJ, Leow AD, Lee HW, Shapira J, Jimenez E, Boeve BB, Caselli RJ, Graff-Radford NR, Jack CR, Kramer JH, Miller BL, Bartzokis G, Thompson PM, ... Knopman DS, et al. Patterns of brain atrophy in clinical variants of frontotemporal lobar degeneration. Dementia and Geriatric Cognitive Disorders. 35: 34-50. PMID 23306166 DOI: 10.1159/000345523  0.333
2013 Mielke MM, Roberts RO, Savica R, Cha R, Drubach DI, Christianson T, Pankratz VS, Geda YE, Machulda MM, Ivnik RJ, Knopman DS, Boeve BF, Rocca WA, Petersen RC. Assessing the temporal relationship between cognition and gait: slow gait predicts cognitive decline in the Mayo Clinic Study of Aging. The Journals of Gerontology. Series a, Biological Sciences and Medical Sciences. 68: 929-37. PMID 23250002 DOI: 10.1093/Gerona/Gls256  0.394
2013 Geda YE, Ragossnig M, Roberts LA, Roberts RO, Pankratz VS, Christianson TJ, Mielke MM, Levine JA, Boeve BF, Sochor O, Tangalos EG, Knopman DS, Petersen RC. Caloric intake, aging, and mild cognitive impairment: a population-based study. Journal of Alzheimer's Disease : Jad. 34: 501-7. PMID 23234878 DOI: 10.3233/Jad-121270  0.375
2013 Bressler J, Fornage M, Demerath EW, Knopman DS, Monda KL, North KE, Penman A, Mosley TH, Boerwinkle E. Fat mass and obesity gene and cognitive decline: the Atherosclerosis Risk in Communities Study. Neurology. 80: 92-9. PMID 23136261 DOI: 10.1212/Wnl.0B013E3182768910  0.354
2013 Schneider AL, Gottesman RF, Mosley T, Alonso A, Knopman DS, Coresh J, Sharrett AR, Selvin E. Cognition and incident dementia hospitalization: results from the atherosclerosis risk in communities study. Neuroepidemiology. 40: 117-24. PMID 23095770 DOI: 10.1159/000342308  0.404
2013 Boxer AL, Gold M, Huey E, Hu WT, Rosen H, Kramer J, Gao FB, Burton EA, Chow T, Kao A, Leavitt BR, Lamb B, Grether M, Knopman D, Cairns NJ, et al. The advantages of frontotemporal degeneration drug development (part 2 of frontotemporal degeneration: the next therapeutic frontier). Alzheimer's & Dementia : the Journal of the Alzheimer's Association. 9: 189-98. PMID 23062850 DOI: 10.1016/J.Jalz.2012.03.003  0.336
2013 Boxer AL, Gold M, Huey E, Gao FB, Burton EA, Chow T, Kao A, Leavitt BR, Lamb B, Grether M, Knopman D, Cairns NJ, Mackenzie IR, Mitic L, Roberson ED, et al. Frontotemporal degeneration, the next therapeutic frontier: molecules and animal models for frontotemporal degeneration drug development. Alzheimer's & Dementia : the Journal of the Alzheimer's Association. 9: 176-88. PMID 23043900 DOI: 10.1016/J.Jalz.2012.03.002  0.334
2013 Whitwell JL, Xu J, Mandrekar J, Boeve BF, Knopman DS, Parisi JE, Senjem ML, Dickson DW, Petersen RC, Rademakers R, Jack CR, Josephs KA. Frontal asymmetry in behavioral variant frontotemporal dementia: clinicoimaging and pathogenetic correlates. Neurobiology of Aging. 34: 636-9. PMID 22502999 DOI: 10.1016/J.Neurobiolaging.2012.03.009  0.301
2013 Murray M, Przybelski S, Lesnick T, Liesinger A, Spychalla A, Gunter J, Parisi J, Boeve B, Knopman D, Petersen R, Jack C, Dickson D, Kantarci K. Aberrant tau and amyloid pathology underlies 1H MR spectroscopic alterations in Alzheimer's disease and Lewy body disease Alzheimers & Dementia. 9: 391. DOI: 10.1016/J.Jalz.2013.05.768  0.373
2013 Zhang B, Ferman T, Boeve B, Smith GE, Maroney-Smith M, Knopman D, Jack C, Petersen R, Kantarci K. MRS differentiates people with MCI who progress to dementia with Lewy bodies from people who progress to Alzheimer's disease Alzheimers & Dementia. 9: 374. DOI: 10.1016/J.Jalz.2013.05.729  0.394
2013 Vemuri P, Wiste H, Weigand S, Knopman D, Mielke M, Machulda M, Lowe V, Petersen R, Jack C. P1-282: Effect of APOE and family history of dementia on Alzheimer's disease imaging biomarkers in cognitively normal subjects Alzheimer's & Dementia. 9: P257-P257. DOI: 10.1016/J.Jalz.2013.05.507  0.444
2013 Vemuri P, Wiste H, Weigand S, Knopman D, Mielke M, Machulda M, Lowe V, Petersen R, Jack C. IC-P-136: Effect of APOE and family history of dementia on Alzheimer's imaging biomarkers in cognitively normal individuals Alzheimer's & Dementia. 9: P80-P80. DOI: 10.1016/J.Jalz.2013.05.133  0.42
2013 Vemuri P, Lesnick T, Przybelski S, Knopman D, Machulda M, Lowe V, Mielke M, Roberts R, Geda Y, Gregg B, Senjem M, Gunter J, Petersen R, Jack C. P3-217: Effect of intellectual lifestyle and Alzheimer's disease biomarkers on rate of cognitive decline: Mayo Clinic Study of Aging Alzheimer's & Dementia. 9: P635-P635. DOI: 10.1016/J.Jalz.2013.05.1290  0.357
2013 Bruns M, Bristow K, Monsell S, Aakre J, Kukull W, Pankratz V, Knopman D, Graff-Radford N, Miller B, Laden F, Dickinson S, Mesulam M, Boeve B. Similar maximal educational attainment in people with dementia: Association with pathologically diagnosed frontotemporal lobar degeneration, Alzheimer's disease and Lewy body disease? Alzheimers & Dementia. 9: 631. DOI: 10.1016/J.Jalz.2013.05.1278  0.393
2013 Mielke M, Wiste H, Savica R, Leibson C, Wiegand S, Knopman D, Vemuri P, Roberts R, Lowe V, Geda Y, Petersen R, Jack C. Association between head trauma, amyloid, and neurodegeneration in a population-based study of cognitively normal participants and participants with mild cognitive impairment Alzheimers & Dementia. 9: 616. DOI: 10.1016/J.Jalz.2013.05.1245  0.394
2013 Lowe V, Weigand S, Senjem M, Vemuri P, Kantarci K, Knopman D, Boeve B, Petersen R, Jack CR. IC-P-102: Hypometabolism in PiB-positive, population-based, cognitively normal subjects with and without APOE-ɛ4 Alzheimer's & Dementia. 9: P59-P59. DOI: 10.1016/J.Jalz.2013.05.099  0.354
2013 Nedelska Z, Ferman T, Boeve B, Weigand SD, Przybelski S, Gunter J, Wille S, Murray M, Smith GE, Geda Y, Knopman D, Petersen R, Jack CR, Parisi J, Dickson D, et al. Regional and whole-brain atrophy rates in autopsy-confirmed dementia with Lewy bodies and Alzheimer's disease Alzheimers & Dementia. 9. DOI: 10.1016/J.Jalz.2013.05.065  0.389
2013 Zhang B, Ferman T, Boeve B, Smith GE, Maroney-Smith M, Knopman D, Jack CR, Petersen R, Kantarci K. MRS differentiates MCI patients who progress to dementia with Lewy bodies and Alzheimer's disease Alzheimers & Dementia. 9: 37. DOI: 10.1016/J.Jalz.2013.05.056  0.384
2013 Mielke M, Wiste H, Weigand S, Vemuri P, Lowe V, Machulda M, Roberts R, Knopman D, Kantarci K, Geda Y, Boeve B, Petersen R, Jack C. IC-P-028: CogState computerized testing is associated with amyloid and FDG-PET: Implications for secondary preventive trials Alzheimer's & Dementia. 9: P24-P24. DOI: 10.1016/J.Jalz.2013.05.029  0.346
2013 Mielke M, Wiste H, Savica R, Leibson C, Weigand S, Knopman D, Vemuri P, Roberts R, Lowe V, Geda Y, Petersen R, Jack C. Association between head trauma, amyloid and neurodegeneration in a population-based study of cognitively normal and mild cognitive impairment participants Alzheimers & Dementia. 9. DOI: 10.1016/J.Jalz.2013.05.028  0.399
2013 Knopman D, Jack C, Wiste H, Weigand S, Vemuri P, Mielke M, Roberts R, Machulda M, Lowe V, Boeve B, Kantarci K, Petersen R. Combinations of amyloid and neurodegeneration biomarkers have a differential impact on cognition Alzheimers & Dementia. 9. DOI: 10.1016/J.Jalz.2013.04.344  0.392
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