Robert Karoly, Ph.D. - Related publications

Affiliations: 
2010 Semmelweis Egyetem, Hungary 
Area:
Neuroscience Biology
NOTE: We are testing a new system for identifying relevant work based on semantic analysis that identifies similarities between recently published papers and the current author's publications. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches.
50 most relevant papers in past 60 days:
Year Citation  Score
2020 Cai S, Tuohy P, Ma C, Kitamura N, Gomez K, Zhou Y, Ran D, Bellampalli SS, Yu J, Luo S, Dorame A, Ngan Pham NY, Molnar G, Streicher JM, Patek M, et al. A modulator of the low-voltage activated T-type calcium channel that reverses HIV glycoprotein 120-, paclitaxel-, and spinal nerve ligation-induced peripheral neuropathies. Pain. PMID 32541387 DOI: 10.1097/j.pain.0000000000001955   
2020 Sherikar AS, Bhatia MS, Dhavale RP. Identification and Investigation of Chalcone Derivatives as Calcium Channel Blockers: Pharmacophore modeling, Docking studies, In-vitro screening, and 3D-QSAR Analysis. Current Computer-Aided Drug Design. PMID 32664842 DOI: 10.2174/1573409916666200714143930   
2020 Montandon GG, Cassoli JS, Peigneur S, Braga TV, Moreira Dos Santos D, Bittencourt Paiva AL, Ricardo de Moraes É, Kushmerick C, Borges MH, Richardson M, Monteiro de Castro Pimenta A, Kjeldsen F, Vasconcelos Diniz MR, Tytgat J, Elena de Lima M. GiTx1(β/κ-theraphotoxin-Gi1a), a novel toxin from the venom of Brazilian tarantula Grammostola iheringi (Mygalomorphae, Theraphosidae): Isolation, structural assessments and activity on voltage-gated ion channels. Biochimie. PMID 32717411 DOI: 10.1016/j.biochi.2020.07.008   
2020 Montandon GG, Cassoli JS, Peigneur S, Braga TV, Moreira Dos Santos D, Bittencourt Paiva AL, Ricardo de Moraes É, Kushmerick C, Borges MH, Richardson M, Monteiro de Castro Pimenta A, Kjeldsen F, Vasconcelos Diniz MR, Tytgat J, Elena de Lima M. GiTx1(β/κ-theraphotoxin-Gi1a), a novel toxin from the venom of Brazilian tarantula Grammostola iheringi (Mygalomorphae, Theraphosidae): Isolation, structural assessments and activity on voltage-gated ion channels. Biochimie. PMID 32717411 DOI: 10.1016/j.biochi.2020.07.008   
2020 Montandon GG, Cassoli JS, Peigneur S, Braga TV, Moreira Dos Santos D, Bittencourt Paiva AL, Ricardo de Moraes É, Kushmerick C, Borges MH, Richardson M, Monteiro de Castro Pimenta A, Kjeldsen F, Vasconcelos Diniz MR, Tytgat J, Elena de Lima M. GiTx1(β/κ-theraphotoxin-Gi1a), a novel toxin from the venom of Brazilian tarantula Grammostola iheringi (Mygalomorphae, Theraphosidae): Isolation, structural assessments and activity on voltage-gated ion channels. Biochimie. PMID 32717411 DOI: 10.1016/j.biochi.2020.07.008   
2020 Van Theemsche KM, Van de Sande DV, Snyders DJ, Labro AJ. Hydrophobic Drug/Toxin Binding Sites in Voltage-Dependent K and Na Channels. Frontiers in Pharmacology. 11: 735. PMID 32499709 DOI: 10.3389/fphar.2020.00735   
2020 Zhu W, Li T, Silva JR, Chen J. Conservation and divergence in NaChBac and Na1.7 pharmacology reveals novel drug interaction mechanisms. Scientific Reports. 10: 10730. PMID 32612253 DOI: 10.1038/s41598-020-67761-5   
2020 Ai X, Wu Y, Lu W, Zhang X, Zhao L, Tu P, Wang K, Jiang Y. A Precise Microfluidic Assay in Single-Cell Profile for Screening of Transient Receptor Potential Channel Modulators. Advanced Science (Weinheim, Baden-Wurttemberg, Germany). 7: 2000111. PMID 32537418 DOI: 10.1002/advs.202000111   
2020 Ai X, Wu Y, Lu W, Zhang X, Zhao L, Tu P, Wang K, Jiang Y. A Precise Microfluidic Assay in Single-Cell Profile for Screening of Transient Receptor Potential Channel Modulators. Advanced Science (Weinheim, Baden-Wurttemberg, Germany). 7: 2000111. PMID 32537418 DOI: 10.1002/advs.202000111   
2020 Hasan S, Megaro A, Cenciarini M, Coretti L, Botti FM, Imbrici P, Steinbusch HWM, Hunter T, Hunter G, Pessia M, D'Adamo MC. Electromechanical coupling of the Kv1.1 voltage-gated K channel is fine-tuned by the simplest amino acid residue in the S4-S5 linker. Pflugers Archiv : European Journal of Physiology. PMID 32577860 DOI: 10.1007/s00424-020-02414-0   
2020 Fletcher-Taylor S, Thapa P, Sepela RJ, Kaakati R, Yarov-Yarovoy V, Sack JT, Cohen BE. Distinguishing Potassium Channel Resting State Conformations in Live Cells with Environment-Sensitive Fluorescence. Acs Chemical Neuroscience. PMID 32579336 DOI: 10.1021/acschemneuro.0c00276   
2020 Kwon Y, Haam CE, Byeon S, Choi SJ, Shin DH, Choi SK, Lee YH. Vasodilatory Effect of Extract in Rat Mesenteric Arteries. Molecules (Basel, Switzerland). 25. PMID 32664327 DOI: 10.3390/molecules25143160   
2020 Neumaier F, Alpdogan S, Hescheler J, Schneider T. Zn2+-induced changes in Cav2.3 channel function: An electrophysiological and modeling study. The Journal of General Physiology. 152. PMID 32559275 DOI: 10.1085/jgp.202012585   
2020 Kanyo R, Wang CK, Locskai LF, Li J, Allison WT, Kurata HT. Functional and behavioral signatures of Kv7 activator drug subtypes. Epilepsia. PMID 32652600 DOI: 10.1111/epi.16592   
2020 Kasap M, Dwyer DS. Clozapine, nimodipine and endosulfan differentially suppress behavioral defects caused by gain-of-function mutations in a two-pore domain K channel (UNC-58). Neuroscience Research. PMID 32681854 DOI: 10.1016/j.neures.2020.07.006   
2020 Weiss N, Zamponi GW. Opioid Receptor Regulation of Neuronal Voltage-Gated Calcium Channels. Cellular and Molecular Neurobiology. PMID 32514826 DOI: 10.1007/s10571-020-00894-3   
2020 Rohaim A, Gong L, Li J, Rui H, Blachowicz L, Roux B. Open and closed structures of a barium-blocked potassium channel. Journal of Molecular Biology. PMID 32615129 DOI: 10.1016/j.jmb.2020.06.012   
2020 Absalom NL, Liao VW, Chebib M. Ligand-gated ion channels in genetic disorders and the question of efficacy. The International Journal of Biochemistry & Cell Biology. 105806. PMID 32679079 DOI: 10.1016/j.biocel.2020.105806   
2020 Guan W, Stephens RF, Mourad O, Mehta A, Fux J, Spafford JD. Unique cysteine-enriched, D2L5 and D4L6 extracellular loops in Ca3 T-type channels alter the passage and block of monovalent and divalent ions. Scientific Reports. 10: 12404. PMID 32710088 DOI: 10.1038/s41598-020-69197-3   
2020 Chandra S, Wang Z, Tao X, Chen O, Luo X, Ji RR, Bortsov AV. Computer-aided Discovery of a New Nav1.7 Inhibitor for Treatment of Pain and Itch. Anesthesiology. 133: 611-627. PMID 32788559 DOI: 10.1097/ALN.0000000000003427   
2020 Zhao Y, Ung PM, Zahoránszky-Kőhalmi G, Zakharov AV, Martinez NJ, Simeonov A, Glaaser IW, Rai G, Schlessinger A, Marugan JJ, Slesinger PA. Identification of a G-Protein-Independent Activator of GIRK Channels. Cell Reports. 31: 107770. PMID 32553165 DOI: 10.1016/j.celrep.2020.107770   
2020 Thull S, Neacsu C, O'Reilly AO, Bothe S, Hausmann R, Huth T, Meents J, Lampert A. Dataset of electrophysiological patch-clamp recordings of the effect of the compounds deltamethrin, ATx-II and β4-peptide on human cardiac Nav1.5 sodium channel gating properties. Data in Brief. 31: 105844. PMID 32637473 DOI: 10.1016/j.dib.2020.105844   
2020 Mathie A, Veale EL, Cunningham KP, Holden RG, Wright PD. Two-Pore Domain Potassium Channels as Drug Targets: Anesthesia and Beyond. Annual Review of Pharmacology and Toxicology. PMID 32679007 DOI: 10.1146/annurev-pharmtox-030920-111536   
2020 Li C, Chen H, Chen Q, Shi H, Yang X, Wang K, Liu J. Lipophilic G-quadruplex Isomers as Biomimetic Ion Channels for Conformation- dependent Selective Transmembrane Transport. Analytical Chemistry. PMID 32564593 DOI: 10.1021/acs.analchem.0c02222   
2020 Cardoso FC. Multi-targeting sodium and calcium channels using venom peptides for the treatment of complex ion channels-related diseases. Biochemical Pharmacology. 114107. PMID 32579958 DOI: 10.1016/j.bcp.2020.114107   
2020 An JR, Seo MS, Jung HS, Heo R, Kang M, Ha KS, Park H, Park WS. The inhibitory effect of ziprasidone on voltage-dependent K channels in coronary arterial smooth muscle cells. Biochemical and Biophysical Research Communications. 529: 191-197. PMID 32703410 DOI: 10.1016/j.bbrc.2020.06.038   
2020 Milenkovic S, Bodrenko IV, Lagostena L, Gradogna A, Serra G, Bosin A, Carpaneto A, Ceccarelli M. The mechanism and energetics of a ligand-controlled hydrophobic gate in a mammalian two pore channel. Physical Chemistry Chemical Physics : Pccp. 22: 15664-15674. PMID 32618303 DOI: 10.1039/d0cp00805b   
2020 Kudaibergenova M, Guo J, Khan HM, Zahid F, Lees-Miller J, Noskov SY, Duff HJ. Allosteric Coupling Between Drug Binding and the Aromatic Cassette in the Pore Domain of the hERG1 Channel: Implications for a State-Dependent Blockade. Frontiers in Pharmacology. 11: 914. PMID 32694995 DOI: 10.3389/fphar.2020.00914   
2020 Morán-Zendejas R, Delgado-Ramírez M, Xu J, Valdés-Abadía B, Aréchiga-Figueroa IA, Cui M, Rodríguez-Menchaca AA. In vitro and in silico characterization of the inhibition of Kir4.1 channels by aminoglycoside antibiotics. British Journal of Pharmacology. PMID 32726456 DOI: 10.1111/bph.15214   
2020 Quan XJ, Zou BC, Qin B, Dai F, Luo HS, Wang JH. [Effect of L-cysteine on colonic motility and the underlying mechanism]. Sheng Li Xue Bao : [Acta Physiologica Sinica]. 72: 299-307. PMID 32572428   
2020 Zhou X, Xu Y, Wang G, Jia Y. Ionic channel blockage in stochastic Hodgkin-Huxley neuronal model driven by multiple oscillatory signals. Cognitive Neurodynamics. 14: 569-578. PMID 32655717 DOI: 10.1007/s11571-020-09593-7   
2020 Zhao J, Lin King JV, Paulsen CE, Cheng Y, Julius D. Irritant-evoked activation and calcium modulation of the TRPA1 receptor. Nature. PMID 32641835 DOI: 10.1038/s41586-020-2480-9   
2020 Wang H, Li S, Wang X, He C, Wang T, Wang Y, Guo W. Vasodilation activity of dipfluzine metabolites in isolated rat basilar arteries and their underlying mechanisms. Environmental Toxicology and Pharmacology. 103430. PMID 32544426 DOI: 10.1016/j.etap.2020.103430   
2020 Peters CH, Watkins AR, Poirier OL, Ruben PC. E1784K, the most common Brugada syndrome and long-QT syndrome type 3 mutant, disrupts sodium channel inactivation through two separate mechanisms. The Journal of General Physiology. 152. PMID 32569350 DOI: 10.1085/jgp.202012595   
2020 Miyano K, Ohbuchi K, Sudo Y, Minami K, Yokoyama T, Yamamoto M, Uzu M, Nonaka M, Shiraishi S, Murata H, Higami Y, Uezono Y. A novel method for evaluating activity of transient receptor potential channels using a cellular dielectric spectroscopy. Journal of Pharmacological Sciences. 143: 320-324. PMID 32505645 DOI: 10.1016/j.jphs.2020.05.001   
2020 Vickstrom CR, Liu X, Zhang Y, Mu L, Kelly TJ, Yan X, Hu MM, Snarrenberg ST, Liu QS. T-type calcium channels contribute to burst firing in a subpopulation of medial habenula neurons. Eneuro. PMID 32719103 DOI: 10.1523/ENEURO.0201-20.2020   
2020 Chan MH, Chen HH, Lo YC, Wu SN. Effectiveness in the Block by Honokiol, a Dimerized Allylphenol from , of Hyperpolarization-Activated Cation Current and Delayed-Rectifier K Current. International Journal of Molecular Sciences. 21. PMID 32549398 DOI: 10.3390/ijms21124260   
2020 Collaço RC, Hyslop S, Rocha T, Dorce VAC, Rowan EG, Antunes E. Neurotoxicity of Tityus bahiensis (brown scorpion) venom in sympathetic vas deferens preparations and neuronal cells. Archives of Toxicology. PMID 32548756 DOI: 10.1007/s00204-020-02799-y   
2020 Zhang M, Zou B, Gunaratna MJ, Weerasekara S, Tong Z, Nguyen TDT, Koldas S, Cao WS, Pascual C, Xie XS, Hua DH. SYNTHESIS OF 1,3,4-OXADIAZOLES AS SELECTIVE T-TYPE CALCIUM CHANNEL INHIBITORS. Heterocycles. 101: 145-164. PMID 32773946 DOI: 10.3987/com-19-s(f)5   
2020 Guet-McCreight A, Skinner FK. Computationally going where experiments cannot: a dynamical assessment of dendritic ion channel currents during -like states. F1000research. 9: 180. PMID 32595950 DOI: 10.12688/f1000research.22584.2   
2020 Hansted AK, Jensen LJ, Olesen J, Jansen-Olesen I. Localization of TRPA1 channels and characterization of TRPA1 mediated responses in dural and pial arteries in vivo after intracarotid infusion of NaS. Cephalalgia : An International Journal of Headache. 333102420937724. PMID 32611244 DOI: 10.1177/0333102420937724   
2020 Liu Y, Mikrani R, He Y, Faran Asraf Baig MM, Abbas M, Naveed M, Tang M, Zhang Q, Li C, Zhou X. TRPM8 channels: A review of distribution and clinical role. European Journal of Pharmacology. 173312. PMID 32610057 DOI: 10.1016/j.ejphar.2020.173312   
2020 Thapak P, Vaidya B, Joshi HC, Singh JN, Sharma SS. Therapeutic Potential of Pharmacological Agents Targeting TRP Channels in CNS Disorders. Pharmacological Research. 105026. PMID 32562815 DOI: 10.1016/j.phrs.2020.105026   
2020 Shi YP, Pang Z, Venkateshappa R, Gunawan M, Kemp J, Truong E, Chang CE, Lin E, Shafaattalab S, Faizi S, Rayani K, Tibbits GF, Claydon VE, Claydon T. The hERG channel activator, RPR260243, enhances protective I current in early refractory reducing arrhythmogenicity in zebrafish hearts. American Journal of Physiology. Heart and Circulatory Physiology. PMID 32559136 DOI: 10.1152/ajpheart.00038.2020   
2020 Thompson E, Eldstrom J, Fedida D. Hormonal Signaling Actions on Kv7.1 (KCNQ1) Channels. Annual Review of Pharmacology and Toxicology. PMID 32667860 DOI: 10.1146/annurev-pharmtox-010919-023645   
2020 Kuo PC, Kao ZH, Lee SW, Wu SN. Effects of Sesamin, the Major Furofuran Lignan of Sesame Oil, on the Amplitude and Gating of Voltage-Gated Na and K Currents. Molecules (Basel, Switzerland). 25. PMID 32635522 DOI: 10.3390/molecules25133062   
2020 Black KA, He S, Jin R, Miller DM, Bolla JR, Clarke OB, Johnson P, Windley M, Burns CJ, Hill AP, Laver D, Robinson CV, Smith BJ, Gulbis JM. A constricted opening in Kir channels does not impede potassium conduction. Nature Communications. 11: 3024. PMID 32541684 DOI: 10.1038/s41467-020-16842-0   
2020 Pai VP, Cervera J, Mafe S, Willocq V, Lederer EK, Levin M. HCN2 Channel-Induced Rescue of Brain Teratogenesis Local and Long-Range Bioelectric Repair. Frontiers in Cellular Neuroscience. 14: 136. PMID 32528251 DOI: 10.3389/fncel.2020.00136   
2020 Ni H, Iseppe AF, Giles WR, Narayan SM, Zhang H, Edwards AG, Morotti S, Grandi E. Populations of in silico myocytes and tissues reveal synergy of multi-atrial-predominant K -current block in atrial fibrillation. British Journal of Pharmacology. PMID 32667679 DOI: 10.1111/bph.15198   
2020 Zybura AS, Baucum AJ, Rush AM, Cummins TR, Hudmon A. CaMKII enhances voltage-gated sodium channel Nav1.6 activity and neuronal excitability. The Journal of Biological Chemistry. PMID 32611770 DOI: 10.1074/jbc.RA120.014062