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My N. Helms - Publications

Affiliations: 
Emory University, Atlanta, GA 
Area:
sodium channels
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40 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2021 Grant GJ, Mimche PN, Paine R, Liou TG, Qian WJ, Helms MN. Enhanced epithelial sodium channel activity in neonatal Scnn1b mouse lung attenuates high oxygen induced lung injury. American Journal of Physiology. Lung Cellular and Molecular Physiology. PMID 33949206 DOI: 10.1152/ajplung.00538.2020  0.301
2020 Grant GJ, Coca C, Zhao XM, Helms MN. Oxidized Glutathione Increases Delta-Subunit Expressing Epithelial Sodium Channel Activity in Oocytes. Emedical Research. 2. PMID 32656545  0.31
2020 Grant GJ, Liou TG, Paine R, Helms MN. High Mobility Group Box-1 Increases Epithelial Sodium Channel Activity and Inflammation via the Receptor for Advanced Glycation End Products. American Journal of Physiology. Cell Physiology. PMID 31913693 DOI: 10.1152/Ajpcell.00291.2019  0.412
2020 Grant GJ, Mogan CA, Liou TG, Helms MN. Role of cystic fibrosis transmembrane conductance regulator in FHC colon epithelial cell dysfunction and colon cancer The Faseb Journal. 34: 1-1. DOI: 10.1096/Fasebj.2020.34.S1.03534  0.328
2018 Downs CA, Johnson NM, Tsaprailis G, Helms MN. RAGE-induced changes in the proteome of alveolar epithelial cells. Journal of Proteomics. 177: 11-20. PMID 29448054 DOI: 10.1016/J.Jprot.2018.02.010  0.383
2017 Downs CA, Johnson NM, Coca C, Helms MN. Angiotensin II regulates δ-ENaC in human umbilical vein endothelial cells. Microvascular Research. PMID 29051045 DOI: 10.1016/J.Mvr.2017.10.001  0.375
2016 Van Avermaete AE, Trac PT, Gauthier TW, Helms MN. Real-time X-ray Imaging of Lung Fluid Volumes in Neonatal Mouse Lung. Journal of Visualized Experiments : Jove. PMID 27500410 DOI: 10.3791/52751  0.346
2015 Downs CA, Kreiner L, Zhao XM, Trac P, Johnson NM, Hansen JM, Brown LA, Helms MN. Oxidized glutathione (GSSG) inhibits epithelial sodium channel activity in primary alveolar epithelial cells. American Journal of Physiology. Lung Cellular and Molecular Physiology. 308: L943-52. PMID 25713321 DOI: 10.1152/Ajplung.00213.2014  0.434
2015 Downs CA, Kreiner LH, Johnson NM, Brown LA, Helms MN. Receptor for advanced glycation end-products regulates lung fluid balance via protein kinase C-gp91(phox) signaling to epithelial sodium channels. American Journal of Respiratory Cell and Molecular Biology. 52: 75-87. PMID 24978055 DOI: 10.1165/Rcmb.2014-0002Oc  0.382
2014 Helms MN, Trac P. ERp29, a chaperone protein ushering in new insights on ion transport regulation. Focus on "ERp29 regulates epithelial sodium channel functional expression by promoting channel cleavage". American Journal of Physiology. Cell Physiology. 307: C699-700. PMID 25009112 DOI: 10.1152/Ajpcell.00217.2014  0.344
2014 Vyas-Read S, Wang W, Kato S, Colvocoresses-Dodds J, Fifadara NH, Gauthier TW, Helms MN, Carlton DP, Brown LA. Hyperoxia induces alveolar epithelial-to-mesenchymal cell transition. American Journal of Physiology. Lung Cellular and Molecular Physiology. 306: L326-40. PMID 24375795 DOI: 10.1152/Ajplung.00074.2013  0.323
2013 Downs CA, Helms MN. Regulation of ion transport by oxidants. American Journal of Physiology. Lung Cellular and Molecular Physiology. 305: L595-603. PMID 24014684 DOI: 10.1152/Ajplung.00212.2013  0.393
2013 Trac D, Liu B, Pao AC, Thomas SV, Park M, Downs CA, Ma HP, Helms MN. Fulvene-5 inhibition of Nadph oxidases attenuates activation of epithelial sodium channels in A6 distal nephron cells. American Journal of Physiology. Renal Physiology. 305: F995-F1005. PMID 23863470 DOI: 10.1152/Ajprenal.00098.2013  0.422
2013 Downs CA, Kreiner LH, Trac DQ, Helms MN. Acute effects of cigarette smoke extract on alveolar epithelial sodium channel activity and lung fluid clearance. American Journal of Respiratory Cell and Molecular Biology. 49: 251-9. PMID 23526224 DOI: 10.1165/Rcmb.2012-0234Oc  0.416
2013 Downs CA, Trac D, Brewer EM, Brown LA, Helms MN. Chronic alcohol ingestion changes the landscape of the alveolar epithelium. Biomed Research International. 2013: 470217. PMID 23509726 DOI: 10.1155/2013/470217  0.313
2013 Downs CA, Trac DQ, Kreiner LH, Eaton AF, Johnson NM, Brown LA, Helms MN. Ethanol alters alveolar fluid balance via Nadph oxidase (NOX) signaling to epithelial sodium channels (ENaC) in the lung. Plos One. 8: e54750. PMID 23382956 DOI: 10.1371/Journal.Pone.0054750  0.419
2013 Downs CA, Kumar A, Kreiner LH, Johnson NM, Helms MN. H2O2 regulates lung epithelial sodium channel (ENaC) via ubiquitin-like protein Nedd8. The Journal of Biological Chemistry. 288: 8136-45. PMID 23362276 DOI: 10.1074/Jbc.M112.389536  0.506
2013 Takemura Y, Helms MN, Eaton AF, Self J, Ramosevac S, Jain L, Bao HF, Eaton DC. Cholinergic regulation of epithelial sodium channels in rat alveolar type 2 epithelial cells. American Journal of Physiology. Lung Cellular and Molecular Physiology. 304: L428-37. PMID 23292809 DOI: 10.1152/Ajplung.00129.2012  0.417
2013 Downs CA, Trac DQ, Kreiner LH, Eaton AF, Johnson NM, Brown LA, Helms MN. Correction: Ethanol alters alveolar fluid balance via Nadph oxidase (NOX), signaling to epithelial sodium channels (ENaC) in the lung (PLoS ONE) Plos One. 8. DOI: 10.1371/annotation/9ebb4691-e5ae-4cf8-a368-c15a684a2873  0.319
2012 Downs CA, Kriener LH, Yu L, Eaton DC, Jain L, Helms MN. β-Adrenergic agonists differentially regulate highly selective and nonselective epithelial sodium channels to promote alveolar fluid clearance in vivo. American Journal of Physiology. Lung Cellular and Molecular Physiology. 302: L1167-78. PMID 22505670 DOI: 10.1152/Ajplung.00038.2012  0.43
2012 Goodson P, Kumar A, Jain L, Kundu K, Murthy N, Koval M, Helms MN. Nadph oxidase regulates alveolar epithelial sodium channel activity and lung fluid balance in vivo via O⁻₂ signaling. American Journal of Physiology. Lung Cellular and Molecular Physiology. 302: L410-9. PMID 22160304 DOI: 10.1152/Ajplung.00260.2011  0.468
2011 Thomas SV, Kathpalia PP, Rajagopal M, Charlton C, Zhang J, Eaton DC, Helms MN, Pao AC. Epithelial sodium channel regulation by cell surface-associated serum- and glucocorticoid-regulated kinase 1. The Journal of Biological Chemistry. 286: 32074-85. PMID 21784856 DOI: 10.1074/Jbc.M111.278283  0.41
2011 Kolegraff K, Nava P, Helms MN, Parkos CA, Nusrat A. Loss of desmocollin-2 confers a tumorigenic phenotype to colonic epithelial cells through activation of Akt/β-catenin signaling. Molecular Biology of the Cell. 22: 1121-34. PMID 21325624 DOI: 10.1091/Mbc.E10-10-0845  0.306
2011 Bao H, Guo L, Helms MN, Song J, Ma H, Eaton DC. Elevation of intracellular Ca2+ inhibits epithelial sodium channels by decreasing membrane phosphatidylinositol-4,5-bisphosphate Heart. 97: A14-A14. DOI: 10.1136/Heartjnl-2011-300867.39  0.367
2011 Kumar A, Helms M. 47Thiol-Mediated Regulation of Epithelial Sodium Channels Free Radical Biology and Medicine. 51. DOI: 10.1016/J.Freeradbiomed.2011.10.071  0.422
2010 Helms MN, Torres-Gonzalez E, Goodson P, Rojas M. Direct tracheal instillation of solutes into mouse lung. Journal of Visualized Experiments : Jove. PMID 20834218 DOI: 10.3791/1941  0.327
2010 Takemura Y, Goodson P, Bao HF, Jain L, Helms MN. Rac1-mediated NADPH oxidase release of O2- regulates epithelial sodium channel activity in the alveolar epithelium. American Journal of Physiology. Lung Cellular and Molecular Physiology. 298: L509-20. PMID 20097736 DOI: 10.1152/Ajplung.00230.2009  0.446
2010 Koval M, Ward C, Findley MK, Roser-Page S, Helms MN, Roman J. Extracellular matrix influences alveolar epithelial claudin expression and barrier function. American Journal of Respiratory Cell and Molecular Biology. 42: 172-80. PMID 19423774 DOI: 10.1165/Rcmb.2008-0270Oc  0.335
2009 Eaton DC, Helms MN, Koval M, Bao HF, Jain L. The contribution of epithelial sodium channels to alveolar function in health and disease. Annual Review of Physiology. 71: 403-23. PMID 18831683 DOI: 10.1146/Annurev.Physiol.010908.163250  0.488
2008 Yu L, Helms MN, Yue Q, Eaton DC. Single-channel analysis of functional epithelial sodium channel (ENaC) stability at the apical membrane of A6 distal kidney cells. American Journal of Physiology. Renal Physiology. 295: F1519-27. PMID 18784262 DOI: 10.1152/Ajprenal.00605.2007  0.442
2008 Helms MN, Jain L, Self JL, Eaton DC. Redox regulation of epithelial sodium channels examined in alveolar type 1 and 2 cells patch-clamped in lung slice tissue. The Journal of Biological Chemistry. 283: 22875-83. PMID 18541535 DOI: 10.1074/Jbc.M801363200  0.494
2007 Yu L, Bao HF, Self JL, Eaton DC, Helms MN. Aldosterone-induced increases in superoxide production counters nitric oxide inhibition of epithelial Na channel activity in A6 distal nephron cells. American Journal of Physiology. Renal Physiology. 293: F1666-77. PMID 17804482 DOI: 10.1152/Ajprenal.00444.2006  0.41
2007 Yu L, Eaton DC, Helms MN. Effect of divalent heavy metals on epithelial Na+ channels in A6 cells. American Journal of Physiology. Renal Physiology. 293: F236-44. PMID 17429036 DOI: 10.1152/Ajprenal.00002.2007  0.377
2006 Helms MN, Self J, Bao HF, Job LC, Jain L, Eaton DC. Dopamine activates amiloride-sensitive sodium channels in alveolar type I cells in lung slice preparations. American Journal of Physiology. Lung Cellular and Molecular Physiology. 291: L610-8. PMID 16679376 DOI: 10.1152/Ajplung.00426.2005  0.47
2006 Johnson MD, Bao HF, Helms MN, Chen XJ, Tigue Z, Jain L, Dobbs LG, Eaton DC. Functional ion channels in pulmonary alveolar type I cells support a role for type I cells in lung ion transport. Proceedings of the National Academy of Sciences of the United States of America. 103: 4964-9. PMID 16549766 DOI: 10.1073/Pnas.0600855103  0.478
2006 Helms MN, Chen XJ, Ramosevac S, Eaton DC, Jain L. Dopamine regulation of amiloride-sensitive sodium channels in lung cells. American Journal of Physiology. Lung Cellular and Molecular Physiology. 290: L710-L722. PMID 16284210 DOI: 10.1152/Ajplung.00486.2004  0.347
2005 Helms MN, Liu L, Liang YY, Al-Khalili O, Vandewalle A, Saxena S, Eaton DC, Ma HP. Phosphatidylinositol 3,4,5-trisphosphate mediates aldosterone stimulation of epithelial sodium channel (ENaC) and interacts with gamma-ENaC. The Journal of Biological Chemistry. 280: 40885-91. PMID 16204229 DOI: 10.1074/Jbc.M509646200  0.417
2005 Helms MN, Yu L, Malik B, Kleinhenz DJ, Hart CM, Eaton DC. Role of SGK1 in nitric oxide inhibition of ENaC in Na+-transporting epithelia. American Journal of Physiology. Cell Physiology. 289: C717-26. PMID 15843443 DOI: 10.1152/Ajpcell.00006.2005  0.43
2004 Náray-Fejes-Tóth A, Helms MN, Stokes JB, Fejes-Tóth G. Regulation of sodium transport in mammalian collecting duct cells by aldosterone-induced kinase, SGK1: structure/function studies. Molecular and Cellular Endocrinology. 217: 197-202. PMID 15134818 DOI: 10.1016/J.Mce.2003.10.043  0.395
2003 Helms MN, Fejes-Toth G, Naray-Fejes-Toth A. Hormone-regulated transepithelial Na+ transport in mammalian CCD cells requires SGK1 expression. American Journal of Physiology. Renal Physiology. 284: F480-7. PMID 12429555 DOI: 10.1152/Ajprenal.00299.2002  0.342
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