John H. Krystal, M.D. - Publications

Affiliations: 
Psychiatry Yale University, New Haven, CT 

500 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2021 Thompson SL, Gianessi CA, O'Malley SS, Cavallo DA, Shi JM, Tetrault JM, DeMartini KS, Gueorguieva R, Pittman B, Krystal JH, Taylor JR, Krishnan-Sarin S. Saracatinib Fails to Reduce Alcohol-Seeking and Consumption in Mice and Human Participants. Frontiers in Psychiatry. 12: 709559. PMID 34531767 DOI: 10.3389/fpsyt.2021.709559  1
2021 Patel KT, Stevens MC, Dunlap A, Gallagher A, O'Malley SS, DeMartini K, Potenza MN, Krystal JH, Pearlson GD. Effects of the Fyn kinase inhibitor saracatinib on ventral striatal activity during performance of an fMRI monetary incentive delay task in individuals family history positive or negative for alcohol use disorder. A pilot randomised trial. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. PMID 34475522 DOI: 10.1038/s41386-021-01157-5  1
2021 Krystal JH, Kelmendi B, Petrakis IL. Psychotherapy-supported MDMA treatment for PTSD. Cell Reports. Medicine. 2: 100378. PMID 34467253 DOI: 10.1016/j.xcrm.2021.100378  1
2021 Nichter B, Hill ML, Na PJ, Kline AC, Norman SB, Krystal JH, Southwick SM, Pietrzak RH. Prevalence and Trends in Suicidal Behavior Among US Military Veterans During the COVID-19 Pandemic. Jama Psychiatry. PMID 34431973 DOI: 10.1001/jamapsychiatry.2021.2332  1
2021 Krystal JH, Chow B, Vessicchio J, Henrie AM, Neylan TC, Krystal AD, Marx BP, Xu K, Jindal RD, Davis LL, Schnurr PP, Stein MB, Thase ME, Ventura B, Huang GD, et al. Design of the national adaptive trial for PTSD-related insomnia (NAP study), VA cooperative study program (CSP) #2016. Contemporary Clinical Trials. 106540. PMID 34416369 DOI: 10.1016/j.cct.2021.106540  1
2021 Nestler EJ, Krystal JH. Ronald S. Duman (1954-2020): In Memoriam. Biological Psychiatry. 90: 72-73. PMID 34210386 DOI: 10.1016/j.biopsych.2021.05.010  1
2021 Hill ML, Nichter B, Na PJ, Norman SB, Morland LA, Krystal JH, Pietrzak RH. Mental Health Impact of the COVID-19 Pandemic in U.S. Military Veterans: A Population-Based, Prospective Cohort Study. Psychological Medicine. 1-37. PMID 34120667 DOI: 10.1017/S0033291721002361  1
2021 Haeny AM, Gueorguieva R, Jackson A, Morean ME, Krishnan-Sarin S, DeMartini KS, Pearlson GD, Anticevic A, Krystal JH, O'Malley SS. Individual differences in the associations between risk factors for alcohol use disorder and alcohol use-related outcomes. Psychology of Addictive Behaviors : Journal of the Society of Psychologists in Addictive Behaviors. PMID 34110841 DOI: 10.1037/adb0000733  1
2021 Wendt FR, Pathak GA, Levey DF, Nuñez YZ, Overstreet C, Tyrrell C, Adhikari K, De Angelis F, Tylee DS, Goswami A, Krystal JH, Abdallah CG, Stein MB, Kranzler HR, Gelernter J, et al. Sex-stratified gene-by-environment genome-wide interaction study of trauma, posttraumatic-stress, and suicidality. Neurobiology of Stress. 14: 100309. PMID 33665242 DOI: 10.1016/j.ynstr.2021.100309  1
2021 DeMartini KS, Gueorguieva R, Pearlson G, Krishnan-Sarin S, Anticevic A, Ji LJ, Krystal JH, O'Malley SS. Mapping Data-Driven Individualized Neurobehavioral Phenotypes in Heavy Alcohol Drinkers. Alcoholism, Clinical and Experimental Research. PMID 33605439 DOI: 10.1111/acer.14580  1
2021 Lee EE, Torous J, De Choudhury M, Depp CA, Graham SA, Kim HC, Paulus MP, Krystal JH, Jeste DV. Artificial Intelligence for Mental Healthcare: Clinical Applications, Barriers, Facilitators, and Artificial Wisdom. Biological Psychiatry. Cognitive Neuroscience and Neuroimaging. PMID 33571718 DOI: 10.1016/j.bpsc.2021.02.001  0.04
2020 Hamilton HK, Roach BJ, Cavus I, Teyler TJ, Clapp WC, Ford JM, Tarakci E, Krystal JH, Mathalon DH. Impaired Potentiation of Theta Oscillations During a Visual Cortical Plasticity Paradigm in Individuals With Schizophrenia. Frontiers in Psychiatry. 11: 590567. PMID 33391054 DOI: 10.3389/fpsyt.2020.590567  1
2020 Girgenti MJ, Wang J, Ji D, Cruz DA, Stein MB, Gelernter J, Young KA, Huber BR, Williamson DE, Friedman MJ, Krystal JH, Zhao H, Duman RS. Transcriptomic organization of the human brain in post-traumatic stress disorder. Nature Neuroscience. PMID 33349712 DOI: 10.1038/s41593-020-00748-7  1
2020 Wendt FR, Pathak GA, Lencz T, Krystal JH, Gelernter J, Polimanti R. Multivariate genome-wide analysis of education, socioeconomic status and brain phenome. Nature Human Behaviour. PMID 33349686 DOI: 10.1038/s41562-020-00980-y  1
2020 Barron DS, Gao S, Dadashkarimi J, Greene AS, Spann MN, Noble S, Lake EMR, Krystal JH, Constable RT, Scheinost D. Transdiagnostic, Connectome-Based Prediction of Memory Constructs Across Psychiatric Disorders. Cerebral Cortex (New York, N.Y. : 1991). PMID 33345271 DOI: 10.1093/cercor/bhaa371  1
2020 Steine IM, Nielsen B, Porter PA, Krystal JH, Winje D, Grønli J, Milde AM, Bjorvatn B, Nordhus IH, Pallesen S. Predictors and correlates of lifetime and persistent non-suicidal self-injury and suicide attempts among adult survivors of childhood sexual abuse. European Journal of Psychotraumatology. 11: 1815282. PMID 33312451 DOI: 10.1080/20008198.2020.1815282  1
2020 Wang X, Xie H, Chen T, Cotton AS, Salminen LE, Logue MW, Clarke-Rubright EK, Wall J, Dennis EL, O'Leary BM, Abdallah CG, Andrew E, Baugh LA, Bomyea J, Bruce SE, ... ... Krystal JH, et al. Cortical volume abnormalities in posttraumatic stress disorder: an ENIGMA-psychiatric genomics consortium PTSD workgroup mega-analysis. Molecular Psychiatry. PMID 33288872 DOI: 10.1038/s41380-020-00967-1  1
2020 Tamman AJF, Wendt FR, Pathak GA, Krystal JH, Montalvo-Ortiz JL, Southwick SM, Sippel LM, Gelernter J, Polimanti R, Pietrzak RH. Attachment Style Moderates Polygenic Risk for Posttraumatic Stress in United States Military Veterans: Results From the National Health and Resilience in Veterans Study. Biological Psychiatry. PMID 33276944 DOI: 10.1016/j.biopsych.2020.09.018  1
2020 Krystal JH, Alvarado J, Ball SA, Fortunati FG, Hu M, Ivy ME, Kapo J, Olson KD, Rohrbaugh RM, Sinha R, Tebes JK, Vender RJ, Yonkers KA, Mayes LC. Mobilizing an institutional supportive response for healthcare workers and other staff in the context of COVID-19: The Yale experience. General Hospital Psychiatry. 68: 12-18. PMID 33254081 DOI: 10.1016/j.genhosppsych.2020.11.005  1
2020 Krystal JH. Publisher Correction: Responding to the hidden pandemic for healthcare workers: stress. Nature Medicine. PMID 33247290 DOI: 10.1038/s41591-020-01176-7  0.01
2020 Krystal JH, Barch DM, Carter CS. Introducing a New Journal, Biological Psychiatry: Global Open Science. Biological Psychiatry. 88: 890. PMID 33213699 DOI: 10.1016/j.biopsych.2020.10.005  1
2020 Li L, Li F, Fortunati F, Krystal JH. Association of a Prior Psychiatric Diagnosis With Mortality Among Hospitalized Patients With Coronavirus Disease 2019 (COVID-19) Infection. Jama Network Open. 3: e2023282. PMID 32997123 DOI: 10.1001/jamanetworkopen.2020.23282  0.01
2020 Abdallah CG, Ahn KH, Averill LA, Nemati S, Averill CL, Fouda S, Ranganathan M, Morgan PT, D'Souza DC, Mathalon DH, Krystal JH, Driesen NR. A robust and reproducible connectome fingerprint of ketamine is highly associated with the connectomic signature of antidepressants. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. PMID 32967000 DOI: 10.1038/s41386-020-00864-9  1
2020 Stone LA, Girgenti MJ, Wang J, Ji D, Zhao H, Krystal JH, Duman RS. Cortical Transcriptomic Alterations in Association with Appetitive Neuropeptides and Body Mass Index in Posttraumatic Stress Disorder. The International Journal of Neuropsychopharmacology. PMID 32951025 DOI: 10.1093/Ijnp/Pyaa072  1
2020 Hillmer AT, Angarita GA, Esterlis I, Anderson JM, Nabulsi N, Lim K, Ropchan J, Carson RE, Krystal JH, Malley SSO, Cosgrove KP. Longitudinal imaging of metabotropic glutamate 5 receptors during early and extended alcohol abstinence. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. PMID 32919411 DOI: 10.1038/S41386-020-00856-9  1
2020 Krystal JH. Robert T. Malison, M.D. (1959-2020). Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. PMID 32839525 DOI: 10.1038/S41386-020-00817-2  0.01
2020 Mason GF, Krystal JH. Mapping Lithium in the Brain: New 3-Dimensional Methodology Reveals Regional Distribution in Euthymic Patients With Bipolar Disorder. Biological Psychiatry. 88: 367-368. PMID 32792052 DOI: 10.1016/J.Biopsych.2020.05.023  1
2020 Kaye AP, Krystal JH. Predictive processing in mental illness: Hierarchical circuitry for perception and trauma. Journal of Abnormal Psychology. 129: 629-632. PMID 32757606 DOI: 10.1037/Abn0000628  0.01
2020 Aghajanian GK, Mathé AA, Eriksson E, Krystal JH. Torgny Svensson, M.D., Ph.D. (1945-2020). Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. PMID 32699343 DOI: 10.1038/S41386-020-0770-4  1
2020 Moreno C, Wykes T, Galderisi S, Nordentoft M, Crossley N, Jones N, Cannon M, Correll CU, Byrne L, Carr S, Chen EYH, Gorwood P, Johnson S, Kärkkäinen H, Krystal JH, et al. How mental health care should change as a consequence of the COVID-19 pandemic. The Lancet. Psychiatry. PMID 32682460 DOI: 10.1016/S2215-0366(20)30307-2  1
2020 Krystal JH. Preface: Remembering Ronald Stanton Duman, Ph.D. Advances in Pharmacology (San Diego, Calif.). 89: xv-xvi. PMID 32616216 DOI: 10.1016/S1054-3589(20)30048-X  0.01
2020 Steine IM, Winje D, Krystal JH, Milde AM, Bjorvatn B, Nordhus IH, Grønli J, Pallesen S. Longitudinal Relationships between Perceived Social Support and Symptom Outcomes: Findings from a sample of Adult Survivors of Childhood Sexual Abuse. Child Abuse & Neglect. 107: 104566. PMID 32526550 DOI: 10.1016/J.Chiabu.2020.104566  1
2020 Wallach JD, Krystal JH, Ross JS, O'Malley SS. Characteristics of Ongoing Clinical Trials for Alcohol Use Disorder Registered on ClinicalTrials.gov. Jama Psychiatry. PMID 32459295 DOI: 10.1001/Jamapsychiatry.2020.1167  1
2020 Beck K, Hindley G, Borgan F, Ginestet C, McCutcheon R, Brugger S, Driesen N, Ranganathan M, D'Souza DC, Taylor M, Krystal JH, Howes OD. Association of Ketamine With Psychiatric Symptoms and Implications for Its Therapeutic Use and for Understanding Schizophrenia: A Systematic Review and Meta-analysis. Jama Network Open. 3: e204693. PMID 32437573 DOI: 10.1001/jamanetworkopen.2020.4693  1
2020 Abdallah CG, Krystal JH. Ketamine and rapid acting antidepressants: Are we ready to cure, rather than treat depression? Behavioural Brain Research. 390: 112628. PMID 32407817 DOI: 10.1016/J.Bbr.2020.112628  1
2020 Gur TL, Krystal JH. Biological Psychiatry Podcast Series: Support Resources for the COVID-19 Pandemic. Biological Psychiatry. PMID 32405077 DOI: 10.1016/J.Biopsych.2020.05.008  0.01
2020 Kantrowitz JT, Grinband J, Goff DC, Lahti AC, Marder SR, Kegeles LS, Girgis RR, Sobeih T, Wall MM, Choo TH, Green MF, Yang YS, Lee J, Horga G, Krystal JH, et al. Proof of mechanism and target engagement of glutamatergic drugs for the treatment of schizophrenia: RCTs of pomaglumetad and TS-134 on ketamine-induced psychotic symptoms and pharmacoBOLD in healthy volunteers. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. PMID 32403118 DOI: 10.1038/S41386-020-0706-Z  1
2020 DeMartini KS, Pittman B, Krystal JH, O'Malley SS, Krishnan-Sarin S. Examining the Relationship Between Self-Reported Drinking and In-Laboratory Drinking and Craving: Is There Concordance? Alcoholism, Clinical and Experimental Research. PMID 32352581 DOI: 10.1111/Acer.14329  1
2020 Krystal JH, McNeil RL. Responding to the hidden pandemic for healthcare workers: stress. Nature Medicine. PMID 32350461 DOI: 10.1038/S41591-020-0878-4  0.01
2020 Koblan KS, Kent J, Hopkins SC, Krystal JH, Cheng H, Goldman R, Loebel A. A Non-D2-Receptor-Binding Drug for the Treatment of Schizophrenia. The New England Journal of Medicine. 382: 1497-1506. PMID 32294346 DOI: 10.1056/Nejmoa1911772  0.01
2020 Spiegelman D, Lovato LC, Khudyakov P, Wilkens TL, Adebamowo CA, Adebamowo SN, Appel LJ, Beulens JW, Coughlin JW, Dragsted LO, Edenberg HJ, Eriksen JN, Estruch R, Grobbee DE, Gulayin PE, ... ... Krystal JH, et al. The Moderate Alcohol and Cardiovascular Health Trial (MACH15): Design and methods for a randomized trial of moderate alcohol consumption and cardiometabolic risk. European Journal of Preventive Cardiology. 2047487320912376. PMID 32250171 DOI: 10.1177/2047487320912376  1
2020 Keizer BM, Roache JD, Jones JR, Kalpinski RJ, Porcerelli JH, Krystal JH. Continuous Ketamine Infusion for Pain as an Opportunity for Psychotherapy for PTSD: A Case Series of Ketamine-Enhanced Psychotherapy for PTSD and Pain (KEP-P2). Psychotherapy and Psychosomatics. 1-4. PMID 32248200 DOI: 10.1159/000507095  0.01
2020 Krystal JH, Charney DS, Duman RS. A New Rapid-Acting Antidepressant. Cell. 181: 7. PMID 32243798 DOI: 10.1016/J.Cell.2020.02.033  1
2020 Preller KH, Duerler P, Burt JB, Ji JL, Adkinson B, Stämpfli P, Seifritz E, Repovš G, Krystal JH, Murray JD, Anticevic A, Vollenweider FX. Psilocybin Induces Time-Dependent Changes in Global Functional Connectivity. Biological Psychiatry. PMID 32111343 DOI: 10.1016/J.Biopsych.2019.12.027  1
2020 Hu Y, Ranganathan M, Shu C, Liang X, Ganesh S, Osafo-Addo A, Yan C, Zhang X, Aouizerat BE, Krystal JH, D'Souza DC, Xu K. Single-cell Transcriptome Mapping Identifies Common and Cell-type Specific Genes Affected by Acute Delta9-tetrahydrocannabinol in Humans. Scientific Reports. 10: 3450. PMID 32103029 DOI: 10.1038/S41598-020-59827-1  1
2020 Abdallah CG, Averill LA, Gueorguieva R, Goktas S, Purohit P, Ranganathan M, Sherif M, Ahn KH, D'Souza DC, Formica R, Southwick SM, Duman RS, Sanacora G, Krystal JH. Modulation of the antidepressant effects of ketamine by the mTORC1 inhibitor rapamycin. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. PMID 32092760 DOI: 10.1038/S41386-020-0644-9  1
2020 Krystal JH, Nestler EJ, Picciotto MR. Ronald S. Duman, Ph.D. (1954-2020). Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. PMID 32076104 DOI: 10.1038/S41386-020-0642-Y  1
2020 Garrison KA, DeMartini KS, Corlett PR, Worhunsky PD, Krystal JH, O'Malley SS. Drinking and responses to antidrinking messages among young adults: An fMRI study. Addiction Biology. e12882. PMID 32068323 DOI: 10.1111/Adb.12882  1
2020 Liang X, Justice AC, So-Armah K, Krystal JH, Sinha R, Xu K. DNA methylation signature on phosphatidylethanol, not on self-reported alcohol consumption, predicts hazardous alcohol consumption in two distinct populations. Molecular Psychiatry. PMID 32034291 DOI: 10.1038/S41380-020-0668-X  1
2020 Krystal JH. Imaging the glutamate synapse. Nature Medicine. 26: 165-167. PMID 32015559 DOI: 10.1038/S41591-020-0760-4  0.01
2020 Hartwell EE, Feinn R, Morris PE, Gelernter J, Krystal J, Arias AJ, Hoffman M, Petrakis I, Gueorguieva R, Schacht JP, Oslin D, Anton RF, Kranzler HR. Systematic Review and Meta-Analysis of the Moderating Effect of rs1799971 in OPRM1, the Mu-opioid Receptor Gene, on Response to Naltrexone Treatment of Alcohol Use Disorder. Addiction (Abingdon, England). PMID 31961981 DOI: 10.1111/Add.14975  1
2020 McCutcheon RA, Krystal JH, Howes OD. Dopamine and glutamate in schizophrenia: biology, symptoms and treatment. World Psychiatry : Official Journal of the World Psychiatric Association (Wpa). 19: 15-33. PMID 31922684 DOI: 10.1002/Wps.20693  0.01
2020 Nestler EJ, Krystal JH. Ronald S. Duman (1954–2020) Neuron. 105: 769-770. DOI: 10.1016/J.Neuron.2020.02.018  0.36
2020 Girgenti M, Wang J, Ji D, Cruz D, Stein M, Gelernter J, Young K, Huber B, Williamson D, Friedman M, Krystal J, Zhao H, Duman R. Transcriptomic Organization of Human Posttraumatic Stress Disorder Biological Psychiatry. 87. DOI: 10.1016/J.Biopsych.2020.02.330  1
2020 Wendt F, Pathak G, Lencz T, Krystal J, Gelernter J, Polimanti R. Education and Socioeconomic Status Mask the Identification of Brain Cell Types in GWAS of Mental Health and Disease Biological Psychiatry. 87. DOI: 10.1016/J.Biopsych.2020.02.302  1
2020 Nemati S, Akiki T, Ju Y, Averill C, Fouda S, Dutta A, Mckie S, Krystal J, Deakin B, Averill L, Abdallah C. A Shift in Executive Connectivity Predates and Predicts Response to Treatment in Major Depressive Disorder Biological Psychiatry. 87. DOI: 10.1016/J.Biopsych.2020.02.294  1
2019 Nemati S, Akiki TJ, Roscoe J, Ju Y, Averill CL, Fouda S, Dutta A, McKie S, Krystal JH, Deakin JFW, Averill LA, Abdallah CG. A Unique Brain Connectome Fingerprint Predates and Predicts Response to Antidepressants. Iscience. 23: 100800. PMID 31918047 DOI: 10.1016/J.Isci.2019.100800  1
2019 Suzuki S, Mell MM, O'Malley SS, Krystal JH, Anticevic A, Kober H. Regulation of Craving and Negative Emotion in Alcohol Use Disorder. Biological Psychiatry. Cognitive Neuroscience and Neuroimaging. PMID 31892465 DOI: 10.1016/J.Bpsc.2019.10.005  1
2019 Dennis EL, Disner SG, Fani N, Salminen LE, Logue M, Clarke EK, Haswell CC, Averill CL, Baugh LA, Bomyea J, Bruce SE, Cha J, Choi K, Davenport ND, Densmore M, ... ... Krystal J, et al. Altered white matter microstructural organization in posttraumatic stress disorder across 3047 adults: results from the PGC-ENIGMA PTSD consortium. Molecular Psychiatry. PMID 31857689 DOI: 10.1038/S41380-019-0631-X  1
2019 Holmes SE, Gallezot JD, Davis MT, DellaGioia N, Matuskey D, Nabulsi N, Krystal JH, Javitch JA, DeLorenzo C, Carson RE, Esterlis I. Measuring the effects of ketamine on mGluR5 using [F]FPEB and PET. Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism. 271678X19886316. PMID 31744389 DOI: 10.1177/0271678X19886316  1
2019 Haeny AM, Gueorguieva R, Morean ME, Krishnan-Sarin S, DeMartini KS, Pearlson GD, Anticevic A, Krystal JH, O'Malley SS. The Association of Impulsivity and Family History of Alcohol Use Disorder on Alcohol Use and Consequences. Alcoholism, Clinical and Experimental Research. PMID 31693193 DOI: 10.1111/Acer.14230  1
2019 Krishnan-Sarin S, O'Malley SS, Franco N, Cavallo DA, Tetrault JM, Shi J, Gueorguieva R, Pittman B, Krystal JH. Influence of combined treatment with naltrexone and memantine on alcohol drinking behaviors: a phase II randomized crossover trial. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. PMID 31590179 DOI: 10.1038/S41386-019-0536-Z  1
2019 Mota NP, Cook JM, Smith NB, Tsai J, Harpaz-Rotem I, Krystal JH, Southwick SM, Pietrzak RH. Posttraumatic stress symptom courses in U.S. military veterans: A seven-year, nationally representative, prospective cohort study. Journal of Psychiatric Research. 119: 23-31. PMID 31546045 DOI: 10.1016/J.Jpsychires.2019.09.005  1
2019 Chen MH, Cheng CM, Gueorguieva R, Lin WC, Li CT, Hong CJ, Tu PC, Bai YM, Tsai SJ, Krystal JH, Su TP. Maintenance of antidepressant and antisuicidal effects by D-cycloserine among patients with treatment-resistant depression who responded to low-dose ketamine infusion: a double-blind randomized placebo-control study. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. PMID 31421635 DOI: 10.1038/S41386-019-0480-Y  1
2019 Xu K, Montalvo-Ortiz JL, Zhang X, Southwick SM, Krystal JH, Pietrzak RH, Gelernter J. Epigenome-wide DNA Methylation Association Analysis Identified Novel Loci in Peripheral Cells for Alcohol Consumption among European American Male Veterans. Alcoholism, Clinical and Experimental Research. PMID 31386212 DOI: 10.1111/Acer.14168  1
2019 Averill LA, Abdallah CG, Levey DF, Han S, Harpaz-Rotem I, Kranzler HR, Southwick SM, Krystal JH, Gelernter J, Pietrzak RH. Apolipoprotein E gene polymorphism, posttraumatic stress disorder, and cognitive function in older U.S. veterans: Results from the National Health and Resilience in Veterans Study. Depression and Anxiety. PMID 31385647 DOI: 10.1002/Da.22912  1
2019 Quagliato LA, Cosci F, Shader RI, Silberman EK, Starcevic V, Balon R, Dubovsky SL, Salzman C, Krystal JH, Weintraub SJ, Freire RC, Nardi AE. Selective serotonin reuptake inhibitors and benzodiazepines in panic disorder: A meta-analysis of common side effects in acute treatment. Journal of Psychopharmacology (Oxford, England). 269881119859372. PMID 31304840 DOI: 10.1177/0269881119859372  1
2019 Kaffman A, White JD, Wei L, Johnson FK, Krystal JH. Enhancing the Utility of Preclinical Research in Neuropsychiatry Drug Development. Methods in Molecular Biology (Clifton, N.J.). 2011: 3-22. PMID 31273690 DOI: 10.1007/978-1-4939-9554-7_1  1
2019 Wang W, Zhornitsky S, Le TM, Dhingra I, Zhang S, Krystal JH, Li CR. Cue-elicited craving, thalamic activity, and physiological arousal in adult non-dependent drinkers. Journal of Psychiatric Research. 116: 74-82. PMID 31202048 DOI: 10.1016/J.Jpsychires.2019.06.005  1
2019 Ji JL, Diehl C, Schleifer C, Tamminga CA, Keshavan MS, Sweeney JA, Clementz BA, Hill SK, Pearlson G, Yang G, Creatura G, Krystal JH, Repovs G, Murray J, Winkler A, et al. Schizophrenia Exhibits Bi-directional Brain-Wide Alterations in Cortico-Striato-Cerebellar Circuits. Cerebral Cortex (New York, N.Y. : 1991). PMID 31157363 DOI: 10.1093/Cercor/Bhy306  1
2019 Abdallah CG, Averill CL, Ramage AE, Averill LA, Goktas S, Nemati S, Krystal JH, Roache JD, Resick PA, Young-McCaughan S, Peterson AL, Fox P. Salience Network Disruption in U.S. Army Soldiers With Posttraumatic Stress Disorder. Chronic Stress (Thousand Oaks, Calif.). 3. PMID 31131337 DOI: 10.1177/2470547019850467  1
2019 Steine IM, Skogen JC, Krystal JH, Winje D, Milde AM, Grønli J, Nordhus IH, Bjorvatn B, Pallesen S. Insomnia symptom trajectories among adult survivors of childhood sexual abuse: A longitudinal study. Child Abuse & Neglect. 93: 263-276. PMID 31129428 DOI: 10.1016/J.Chiabu.2019.05.009  1
2019 Davis MT, Hillmer A, Holmes SE, Pietrzak RH, DellaGioia N, Nabulsi N, Matuskey D, Angarita-Africano G, Carson RE, Krystal JH, Esterlis I. In vivo evidence for dysregulation of mGluR5 as a biomarker of suicidal ideation. Proceedings of the National Academy of Sciences of the United States of America. PMID 31085640 DOI: 10.1073/Pnas.1818871116  1
2019 Krystal JH, Yoon G, Petrakis IL. Rigorous Trial Design Is Essential to Understand the Role of Opioid Receptors in Ketamine's Antidepressant Effect-Reply. Jama Psychiatry. PMID 31042270 DOI: 10.1001/Jamapsychiatry.2019.0763  1
2019 Abdallah CG, Averill CL, Ramage AE, Averill LA, Alkin E, Nemati S, Krystal JH, Roache JD, Resick P, Young-McCaughan S, Peterson AL, Fox P. Reduced Salience and Enhanced Central Executive Connectivity Following PTSD Treatment. Chronic Stress (Thousand Oaks, Calif.). 3. PMID 31008419 DOI: 10.1177/2470547019838971  1
2019 Abdallah CG, Roache JD, Averill LA, Young-McCaughan S, Martini B, Gueorguieva R, Amoroso T, Southwick SM, Guthmiller K, López-Roca AL, Lautenschlager K, Mintz J, Litz BT, Williamson DE, Keane TM, ... ... Krystal JH, et al. Repeated ketamine infusions for antidepressant-resistant PTSD: Methods of a multicenter, randomized, placebo-controlled clinical trial. Contemporary Clinical Trials. PMID 30999057 DOI: 10.1016/J.Cct.2019.04.009  1
2019 Holmes SE, Scheinost D, Finnema SJ, Naganawa M, Davis MT, DellaGioia N, Nabulsi N, Matuskey D, Angarita GA, Pietrzak RH, Duman RS, Sanacora G, Krystal JH, Carson RE, Esterlis I. Lower synaptic density is associated with depression severity and network alterations. Nature Communications. 10: 1529. PMID 30948709 DOI: 10.1038/S41467-019-09562-7  1
2019 Duman RS, Sanacora G, Krystal JH. Altered Connectivity in Depression: GABA and Glutamate Neurotransmitter Deficits and Reversal by Novel Treatments. Neuron. 102: 75-90. PMID 30946828 DOI: 10.1016/J.Neuron.2019.03.013  1
2019 Fleming LM, Javitt DC, Carter CS, Kantrowitz JT, Girgis RR, Kegeles LS, Ragland JD, Maddock RJ, Lesh TA, Tanase C, Robinson J, Potter WZ, Carlson M, Wall MM, Choo TH, ... ... Krystal JH, et al. A multicenter study of ketamine effects on functional connectivity: Large scale network relationships, hubs and symptom mechanisms. Neuroimage. Clinical. 22: 101739. PMID 30852397 DOI: 10.1016/J.Nicl.2019.101739  1
2019 Krystal JH, Abdallah CG, Sanacora G, Charney DS, Duman RS. Ketamine: A Paradigm Shift for Depression Research and Treatment. Neuron. 101: 774-778. PMID 30844397 DOI: 10.1016/J.Neuron.2019.02.005  1
2019 Tamman AJF, Montalvo-Ortiz JL, Southwick SM, Krystal JH, Levy BR, Pietrzak RH. Accelerated DNA Methylation Aging in U.S. Military Veterans: Results From the National Health and Resilience in Veterans Study. The American Journal of Geriatric Psychiatry : Official Journal of the American Association For Geriatric Psychiatry. PMID 30792041 DOI: 10.1016/J.Jagp.2019.01.001  1
2019 Homan P, Levy I, Feltham E, Gordon C, Hu J, Li J, Pietrzak RH, Southwick S, Krystal JH, Harpaz-Rotem I, Schiller D. Author Correction: Neural computations of threat in the aftermath of combat trauma. Nature Neuroscience. PMID 30760852 DOI: 10.1038/S41593-019-0356-9  1
2019 Tang Y, Zhou Q, Chang M, Chekroud A, Gueorguieva R, Jiang X, Zhou Y, He G, Rowland M, Wang D, Fu S, Yin Z, Leng H, Wei S, Xu K, ... ... Krystal JH, et al. Altered functional connectivity and low-frequency signal fluctuations in early psychosis and genetic high risk. Schizophrenia Research. PMID 30685394 DOI: 10.1016/J.Schres.2018.12.041  0.48
2019 Homan P, Levy I, Feltham E, Gordon C, Hu J, Li J, Pietrzak RH, Southwick S, Krystal JH, Harpaz-Rotem I, Schiller D. Neural computations of threat in the aftermath of combat trauma. Nature Neuroscience. PMID 30664770 DOI: 10.1038/S41593-018-0315-X  1
2019 Yoon G, Petrakis IL, Krystal JH. Association of Combined Naltrexone and Ketamine With Depressive Symptoms in a Case series of Patients With Depression and Alcohol Use Disorder. Jama Psychiatry. PMID 30624551 DOI: 10.1001/Jamapsychiatry.2018.3990  1
2019 Krystal JH. Celebrating 50 Years of Biological Psychiatry: To the Future, and Beyond. Biological Psychiatry. 85: 2-4. PMID 30527209 DOI: 10.1016/J.Biopsych.2018.08.015  0.01
2019 Burt J, Preller K, Demirtas M, Ji JL, Krystal J, Vollenweider F, Anticevic A, Murray J. S175. Large-Scale Model of Human Cortex Captures LSD-Induced Functional Alterations via HTR2A-Mediated Neural Gain Modulation Biological Psychiatry. 85. DOI: 10.1016/J.Biopsych.2019.03.926  1
2019 Holmes S, Scheinost D, Finnema S, Naganawa M, Davis M, DellaGioia N, Nabulsi N, Matuskey D, Angarita G, Pietrzak R, Duman R, Sanacora G, Krystal J, Carson R, Esterlis I. 142. Synaptic Density Alterations are Associated With Depression Severity and Network Alterations Biological Psychiatry. 85. DOI: 10.1016/J.Biopsych.2019.03.156  1
2018 Chekroud AM, Loho H, Paulus M, Krystal JH. PTSD and the War of Words. Chronic Stress (Thousand Oaks, Calif.). 2: 2470547018767387. PMID 32440582 DOI: 10.1177/2470547018767387  1
2018 Zhornitsky S, Zhang S, Ide JS, Chao HH, Wang W, Le TM, Leeman RF, Bi J, Krystal JH, Li CR. Alcohol Expectancy and Cerebral Responses to Cue-Elicited Craving in Adult Nondependent Drinkers. Biological Psychiatry. Cognitive Neuroscience and Neuroimaging. PMID 30711509 DOI: 10.1016/J.Bpsc.2018.11.012  1
2018 Zhang X, Hu Y, Aouizerat BE, Peng G, Marconi VC, Corley MJ, Hulgan T, Bryant KJ, Zhao H, Krystal JH, Justice AC, Xu K. Machine learning selected smoking-associated DNA methylation signatures that predict HIV prognosis and mortality. Clinical Epigenetics. 10: 155. PMID 30545403 DOI: 10.1186/S13148-018-0591-Z  1
2018 Su TP, Chen MH, Li CT, Lin WC, Hong CJ, Gueorguieva R, Tu PC, Bai YM, Cheng CM, Krystal JH. Correction: Dose-Related Effects of Adjunctive Ketamine in Taiwanese Patients with Treatment-Resistant Depression. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. PMID 30487654 DOI: 10.1038/s41386-018-0253-z  1
2018 Averill CL, Averill LA, Wrocklage KM, Scott JC, Akiki TJ, Schweinsburg B, Southwick SM, Krystal JH, Abdallah CG. Altered White Matter Diffusivity of the Cingulum Angular Bundle in Posttraumatic Stress Disorder. Molecular Neuropsychiatry. 4: 75-82. PMID 30397595 DOI: 10.1159/000490464  1
2018 Pitts BL, Whealin JM, Harpaz-Rotem I, Duman RS, Krystal JH, Southwick SM, Pietrzak RH. BDNF Val66Met polymorphism and posttraumatic stress symptoms in U.S. military veterans: Protective effect of physical exercise. Psychoneuroendocrinology. 100: 198-202. PMID 30388593 DOI: 10.1016/J.Psyneuen.2018.10.011  1
2018 Akiki TJ, Averill CL, Wrocklage KM, Scott JC, Averill LA, Schweinsburg B, Alexander-Bloch A, Martini B, Southwick SM, Krystal JH, Abdallah CG. Topology of brain functional connectivity networks in posttraumatic stress disorder. Data in Brief. 20: 1658-1675. PMID 30364328 DOI: 10.1016/J.Dib.2018.08.198  1
2018 Preller KH, Burt JB, Ji JL, Schleifer CH, Adkinson BD, Stämpfli P, Seifritz E, Repovs G, Krystal JH, Murray JD, Vollenweider FX, Anticevic A. Changes in global and thalamic brain connectivity in LSD-induced altered states of consciousness are attributable to the 5-HT2A receptor. Elife. 7. PMID 30355445 DOI: 10.7554/Elife.35082  1
2018 Zhou H, Cheng Z, Bass N, Krystal JH, Farrer LA, Kranzler HR, Gelernter J. Genome-wide association study identifies glutamate ionotropic receptor GRIA4 as a risk gene for comorbid nicotine dependence and major depression. Translational Psychiatry. 8: 208. PMID 30287806 DOI: 10.1016/J.Biopsych.2018.02.744  1
2018 Chekroud SR, Gueorguieva R, Zheutlin AB, Paulus M, Krumholz HM, Krystal JH, Chekroud AM. Physical activity and mental health - Author's reply. The Lancet. Psychiatry. PMID 30245184 DOI: 10.1016/S2215-0366(18)30354-7  1
2018 Abdallah CG, Averill LA, Akiki TJ, Raza M, Averill CL, Gomaa H, Adikey A, Krystal JH. The Neurobiology and Pharmacotherapy of Posttraumatic Stress Disorder. Annual Review of Pharmacology and Toxicology. PMID 30216745 DOI: 10.1146/Annurev-Pharmtox-010818-021701  1
2018 Zhornitsky S, Ide J, Wang W, Chao H, Zhang S, Hu S, Krystal J, Li CR. Problem drinking, alcohol expectancy and thalamic resting-state functional connectivity in non-dependent adult drinkers. Brain Connectivity. PMID 30198312 DOI: 10.1089/Brain.2018.0633  1
2018 Chekroud SR, Gueorguieva R, Zheutlin AB, Paulus M, Krumholz HM, Krystal JH, Chekroud AM. Association between physical exercise and mental health in 1·2 million individuals in the USA between 2011 and 2015: a cross-sectional study. The Lancet. Psychiatry. PMID 30099000 DOI: 10.1016/S2215-0366(18)30227-X  1
2018 Holmes SE, Scheinost D, DellaGioia N, Davis MT, Matuskey D, Pietrzak RH, Hampson M, Krystal JH, Esterlis I. Cerebellar and prefrontal cortical alterations in PTSD: structural and functional evidence. Chronic Stress (Thousand Oaks, Calif.). 2. PMID 30035247  1
2018 Abdallah CG, De Feyter HM, Averill LA, Jiang L, Averill CL, Chowdhury GMI, Purohit P, de Graaf RA, Esterlis I, Juchem C, Pittman BP, Krystal JH, Rothman DL, Sanacora G, Mason GF. The effects of ketamine on prefrontal glutamate neurotransmission in healthy and depressed subjects. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. PMID 29977074 DOI: 10.1038/S41386-018-0136-3  1
2018 Chekroud AM, Foster D, Zheutlin AB, Gerhard DM, Roy B, Koutsouleris N, Chandra A, Esposti MD, Subramanyan G, Gueorguieva R, Paulus M, Krystal JH. Predicting Barriers to Treatment for Depression in a U.S. National Sample: A Cross-Sectional, Proof-of-Concept Study. Psychiatric Services (Washington, D.C.). appips201800094. PMID 29962307 DOI: 10.1176/Appi.Ps.201800094  1
2018 Nardi AE, Cosci F, Balon R, Weintraub SJ, Freire RC, Krystal JH, Roth T, Silberman EK, Sonino N, Fava GA, Starcevic V, Dubovsky SL, Salzman C, Rickels K, Greenblatt DJ, et al. The Prescription of Benzodiazepines for Panic Disorder: Time for an Evidence-Based Educational Approach. Journal of Clinical Psychopharmacology. 38: 283-285. PMID 29912790 DOI: 10.1097/Jcp.0000000000000908  1
2018 Ide JS, Zhornitsky S, Chao HH, Zhang S, Hu S, Wang W, Krystal JH, Li CR. Thalamic Cortical Error-Related Responses in Adult Social Drinkers: Sex Differences and Problem Alcohol Use. Biological Psychiatry. Cognitive Neuroscience and Neuroimaging. PMID 29859929 DOI: 10.1016/J.Bpsc.2018.04.008  1
2018 Kegeles LS, Horga G, Ghazzaoui R, Rosengard R, Ojeil N, Xu X, Slifstein M, Petrakis I, O'Malley SS, Krystal JH, Abi-Dargham A. Enhanced Striatal Dopamine Release to Expectation of Alcohol: A Potential Risk Factor for Alcohol Use Disorder. Biological Psychiatry. Cognitive Neuroscience and Neuroimaging. PMID 29803635 DOI: 10.1016/J.Bpsc.2018.03.018  1
2018 Abdallah CG, Sanacora G, Duman RS, Krystal JH. The neurobiology of depression, ketamine and rapid-acting antidepressants: Is it glutamate inhibition or activation? Pharmacology & Therapeutics. PMID 29803629 DOI: 10.1016/J.Pharmthera.2018.05.010  1
2018 Balon R, Chouinard G, Cosci F, Dubovsky SL, Fava GA, Freire RC, Greenblatt DJ, Krystal JH, Nardi AE, Rickels K, Roth T, Salzman C, Shader R, Silberman EK, Sonino N, et al. International Task Force on Benzodiazepines. Psychotherapy and Psychosomatics. 1-2. PMID 29788029 DOI: 10.1159/000489538  1
2018 Akiki TJ, Averill CL, Wrocklage KM, Scott JC, Averill LA, Schweinsburg B, Alexander-Bloch A, Martini B, Southwick SM, Krystal JH, Abdallah CG. Default mode network abnormalities in posttraumatic stress disorder: A novel network-restricted topology approach. Neuroimage. PMID 29730491 DOI: 10.1016/J.Neuroimage.2018.05.005  1
2018 Fuehrlein BS, Kachadourian LK, DeVylder EK, Trevisan LA, Potenza MN, Krystal JH, Southwick SM, Pietrzak RH. Trajectories of alcohol consumption in U.S. military veterans: Results from the National Health and Resilience in Veterans Study. The American Journal On Addictions. PMID 29667712 DOI: 10.1111/Ajad.12731  1
2018 Morean ME, DeMartini KS, Foster D, Patock-Peckham J, Garrison KA, Corlett PR, Krystal JH, Krishan-Sarin S, O'Malley SS. The Self-Report Habit Index: Assessing habitual marijuana, alcohol, e-cigarette, and cigarette use. Drug and Alcohol Dependence. 186: 207-214. PMID 29609132 DOI: 10.1016/J.Drugalcdep.2018.01.014  1
2018 Cheng WJ, Chen CH, Chen CK, Huang MC, Pietrzak RH, Krystal JH, Xu K. Similar psychotic and cognitive profile between ketamine dependence with persistent psychosis and schizophrenia. Schizophrenia Research. PMID 29510925 DOI: 10.1016/J.Schres.2018.02.049  1
2018 D'Souza DC, Carson RE, Driesen N, Johannesen J, Ranganathan M, Krystal JH. Dose-Related Target Occupancy and Effects on Circuitry, Behavior, and Neuroplasticity of the Glycine Transporter-1 Inhibitor PF-03463275 in Healthy and Schizophrenia Subjects. Biological Psychiatry. PMID 29499855 DOI: 10.1016/J.Biopsych.2017.12.019  1
2018 Krystal JH, Abdallah CG, Pietrzak RH, Averill LA, Harpaz-Rotem I, Levy I, Kelmendi B, Southwick SM. Locus Coeruleus Hyperactivity in Posttraumatic Stress Disorder: Answers and Questions. Biological Psychiatry. 83: 197-199. PMID 29277190 DOI: 10.1016/J.Biopsych.2017.09.027  1
2018 Preller KH, Burt JB, Ji JL, Schleifer CH, Adkinson BD, Stämpfli P, Seifritz E, Repovs G, Krystal JH, Murray JD, Vollenweider FX, Anticevic A. Author response: Changes in global and thalamic brain connectivity in LSD-induced altered states of consciousness are attributable to the 5-HT2A receptor Elife. DOI: 10.7554/Elife.35082.028  1
2018 Girgenti M, Cruz D, Williamson D, Friedman M, Krystal J, Duman R. T103. Transcriptome Alterations for Posttraumatic Stress Disorder in Human Prefrontal Cortex Biological Psychiatry. 83. DOI: 10.1016/J.Biopsych.2018.02.439  1
2017 Abdallah CG, Averill LA, Krystal JH. A New Journal: Addressing the Behavioral and Biological Effects of Chronic Stress. Chronic Stress (Thousand Oaks, Calif.). 1: 2470547016683296. PMID 32440577 DOI: 10.1177/2470547016683296  1
2017 Kelmendi B, Adams TG, Southwick S, Abdallah CG, Krystal JH. Posttraumatic Stress Disorder: an integrated overview and neurobiological rationale for pharmacology. Clinical Psychology : a Publication of the Division of Clinical Psychology of the American Psychological Association. 24: 281-297. PMID 31404451 DOI: 10.1111/Cpsp.12202  1
2017 Averill CL, Satodiya RM, Scott JC, Wrocklage KM, Schweinsburg B, Averill LA, Akiki TJ, Amoroso T, Southwick SM, Krystal JH, Abdallah CG. Posttraumatic Stress Disorder and Depression Symptom Severities Are Differentially Associated With Hippocampal Subfield Volume Loss in Combat Veterans. Chronic Stress (Thousand Oaks, Calif.). 1. PMID 29520395  1
2017 Zhang X, Hu Y, Justice AC, Li B, Wang Z, Zhao H, Krystal JH, Xu K. DNA methylation signatures of illicit drug injection and hepatitis C are associated with HIV frailty. Nature Communications. 8: 2243. PMID 29269866 DOI: 10.1038/S41467-017-02326-1  1
2017 Logue MW, van Rooij SJH, Dennis EL, Davis SL, Hayes JP, Stevens JS, Densmore M, Haswell CC, Ipser J, Koch SBJ, Korgaonkar M, Lebois LAM, Peverill M, Baker JT, Boedhoe PSW, ... ... Krystal JH, et al. Smaller Hippocampal Volume in Posttraumatic Stress Disorder: A Multisite ENIGMA-PGC Study: Subcortical Volumetry Results From Posttraumatic Stress Disorder Consortia. Biological Psychiatry. PMID 29217296 DOI: 10.1016/J.Biopsych.2017.09.006  1
2017 Mota NP, Han S, Harpaz-Rotem I, Maruff P, Krystal JH, Southwick SM, Gelernter J, Pietrzak RH. Apolipoprotein E gene polymorphism, trauma burden, and posttraumatic stress symptoms in U.S. military veterans: Results from the National Health and Resilience in Veterans Study. Depression and Anxiety. PMID 29172227 DOI: 10.1002/Da.22698  1
2017 Javitt DC, Carter CS, Krystal JH, Kantrowitz JT, Girgis RR, Kegeles LS, Ragland JD, Maddock RJ, Lesh TA, Tanase C, Corlett PR, Rothman DL, Mason G, Qiu M, Robinson J, et al. Utility of Imaging-Based Biomarkers for Glutamate-Targeted Drug Development in Psychotic Disorders: A Randomized Clinical Trial. Jama Psychiatry. PMID 29167877 DOI: 10.1001/Jamapsychiatry.2017.3572  1
2017 Krystal JH, Davis LL, Neylan TC, Raskind M, Schnurr PP, Stein MB, Vessicchio J, Shiner B, Gleason TC, Huang GD. Reply to: It Is Time to Look for New Treatments for Posttraumatic Stress Disorder: Can Sympathetic System Modulation Be an Answer? Biological Psychiatry. PMID 29132654 DOI: 10.1016/J.Biopsych.2017.09.031  1
2017 Yang BZ, Arias AJ, Feinn R, Krystal JH, Gelernter J, Petrakis IL. GRIK1 and GABRA2 Variants Have Distinct Effects on the Dose-Related Subjective Response to Intravenous Alcohol in Healthy Social Drinkers. Alcoholism, Clinical and Experimental Research. PMID 29131352 DOI: 10.1111/Acer.13516  1
2017 Esterlis I, Holmes SE, Sharma P, Krystal JH, DeLorenzo C. Metabotropic Glutamatergic Receptor 5 and Stress Disorders: Knowledge Gained From Receptor Imaging Studies. Biological Psychiatry. PMID 29100629 DOI: 10.1016/J.Biopsych.2017.08.025  1
2017 Watkins LE, Han S, Krystal JH, Southwick SM, Gelernter J, Pietrzak RH. Association Between Functional Polymorphism in Neuropeptide Y Gene Promoter rs16147 and Resilience to Traumatic Stress in US Military Veterans. The Journal of Clinical Psychiatry. 78: e1058-e1059. PMID 29099554 DOI: 10.4088/Jcp.17L11646  1
2017 Abdallah CG, Averill CL, Salas R, Averill LA, Baldwin PR, Krystal JH, Mathew SJ, Mathalon DH. Prefrontal Connectivity and Glutamate Transmission: Relevance to Depression Pathophysiology and Ketamine Treatment. Biological Psychiatry. Cognitive Neuroscience and Neuroimaging. 2: 566-574. PMID 29034354 DOI: 10.1016/J.Bpsc.2017.04.006  1
2017 Taylor JJ, Krystal JH, D'Souza DC, Gerrard JL, Corlett PR. Targeted neural network interventions for auditory hallucinations: Can TMS inform DBS? Schizophrenia Research. PMID 28969932 DOI: 10.1016/J.Schres.2017.09.020  1
2017 Byrne SP, Krystal JH, Rosenheck RA, Vessicchio J, Pietrzak RH. Correlates of Nonimprovement to Pharmacotherapy for Chronic, Antidepressant-Resistant, Military Service-Related Posttraumatic Stress Disorder: Insights From the Veterans Affairs Cooperative Study No. 504. Journal of Clinical Psychopharmacology. PMID 28945664 DOI: 10.1097/Jcp.0000000000000777  1
2017 Krystal JH. Biological Psychiatry: A New Approach to Reviews. Biological Psychiatry. PMID 28918940 DOI: 10.1016/J.Biopsych.2017.07.025  0.01
2017 Tamman AJF, Sippel LM, Han S, Neria Y, Krystal JH, Southwick SM, Gelernter J, Pietrzak RH. Attachment style moderates effects of FKBP5 polymorphisms and childhood abuse on posttraumatic stress symptoms: Results from the National Health and Resilience in Veterans Study. The World Journal of Biological Psychiatry : the Official Journal of the World Federation of Societies of Biological Psychiatry. 1-41. PMID 28891785 DOI: 10.1080/15622975.2017.1376114  1
2017 Averill LA, Abdallah CG, Pietrzak RH, Averill CL, Southwick SM, Krystal JH, Harpaz-Rotem I. Combat Exposure Severity is Associated with Reduced Cortical Thickness in Combat Veterans: A Preliminary Report. Chronic Stress (Thousand Oaks, Calif.). 1. PMID 28845475  1
2017 Krystal JH, Abdallah CG, Averill LA, Kelmendi B, Harpaz-Rotem I, Sanacora G, Southwick SM, Duman RS. Synaptic Loss and the Pathophysiology of PTSD: Implications for Ketamine as a Prototype Novel Therapeutic. Current Psychiatry Reports. 19: 74. PMID 28844076 DOI: 10.1007/S11920-017-0829-Z  1
2017 Akiki TJ, Averill CL, Wrocklage KM, Schweinsburg B, Scott JC, Martini B, Averill LA, Southwick SM, Krystal JH, Abdallah CG. The Association of PTSD Symptom Severity with Localized Hippocampus and Amygdala Abnormalities. Chronic Stress (Thousand Oaks, Calif.). 1. PMID 28825050  1
2017 Andersen AM, Pietrzak RH, Kranzler HR, Ma L, Zhou H, Liu X, Kramer J, Kuperman S, Edenberg HJ, Nurnberger JI, Rice JP, Tischfield JA, Goate A, Foroud TM, Meyers JL, ... ... Krystal JH, et al. Polygenic Scores for Major Depressive Disorder and Risk of Alcohol Dependence. Jama Psychiatry. PMID 28813562 DOI: 10.1001/Jamapsychiatry.2017.2269  1
2017 Holmes SE, Girgenti MJ, Davis MT, Pietrzak RH, DellaGioia N, Nabulsi N, Matuskey D, Southwick S, Duman RS, Carson RE, Krystal JH, Esterlis I. Altered metabotropic glutamate receptor 5 markers in PTSD: In vivo and postmortem evidence. Proceedings of the National Academy of Sciences of the United States of America. PMID 28716937 DOI: 10.1073/Pnas.1701749114  1
2017 Wisco BE, Marx BP, Miller MW, Wolf EJ, Krystal JH, Southwick SM, Pietrzak RH. A comparison of ICD-11 and DSM criteria for posttraumatic stress disorder in two national samples of U.S. military veterans. Journal of Affective Disorders. 223: 17-19. PMID 28715723 DOI: 10.1016/J.Jad.2017.07.006  1
2017 Sippel LM, Han S, Watkins LE, Harpaz-Rotem I, Southwick SM, Krystal JH, Olff M, Sherva R, Farrer LA, Kranzler HR, Gelernter J, Pietrzak RH. Oxytocin receptor gene polymorphisms, attachment, and PTSD: Results from the National Health and Resilience in Veterans Study. Journal of Psychiatric Research. 94: 139-147. PMID 28715704 DOI: 10.1016/J.Jpsychires.2017.07.008  1
2017 Petrakis IL, Ralevski E, Gueorguieva R, O'Malley SS, Arias A, Sevarino KA, Jane JS, O'Brien E, Krystal JH. Mecamylamine Treatment for Alcohol Dependence: A Randomized Controlled Trial. Addiction (Abingdon, England). PMID 28710873 DOI: 10.1111/Add.13943  1
2017 Stefanovics EA, Rosenheck RA, Jones KM, Huang G, Krystal JH. Minimal Clinically Important Differences (MCID) in Assessing Outcomes of Post-Traumatic Stress Disorder. The Psychiatric Quarterly. PMID 28634644 DOI: 10.1007/S11126-017-9522-Y  1
2017 Su TP, Chen MH, Li CT, Lin WC, Hong CJ, Gueorguieva R, Tu PC, Bai YM, Cheng CM, Krystal JH. Dose-Related Effects of Adjunctive Ketamine in Taiwanese Patients with Treatment-Resistant Depression. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. PMID 28492279 DOI: 10.1038/Npp.2017.94  1
2017 Abdallah CG, Southwick SM, Krystal JH. Neurobiology of posttraumatic stress disorder (PTSD): A path from novel pathophysiology to innovative therapeutics. Neuroscience Letters. 649: 130-132. PMID 28478864 DOI: 10.1016/J.Neulet.2017.04.046  1
2017 Krystal JH, Davis LL, Neylan TC, A Raskind M, Schnurr PP, Stein MB, Vessicchio J, Shiner B, Gleason TD, Huang GD. It Is Time to Address the Crisis in the Pharmacotherapy of Posttraumatic Stress Disorder: A Consensus Statement of the PTSD Psychopharmacology Working Group. Biological Psychiatry. PMID 28454621 DOI: 10.1016/J.Biopsych.2017.03.007  1
2017 Krystal JH, Anticevic A, Yang GJ, Dragoi G, Driesen NR, Wang XJ, Murray JD. Impaired Tuning of Neural Ensembles and the Pathophysiology of Schizophrenia: A Translational and Computational Neuroscience Perspective. Biological Psychiatry. 81: 874-885. PMID 28434616 DOI: 10.1016/J.Biopsych.2017.01.004  1
2017 Foss-Feig JH, Adkinson BD, Ji JL, Yang G, Srihari VH, McPartland JC, Krystal JH, Murray JD, Anticevic A. Searching for Cross-Diagnostic Convergence: Neural Mechanisms Governing Excitation and Inhibition Balance in Schizophrenia and Autism Spectrum Disorders. Biological Psychiatry. 81: 848-861. PMID 28434615 DOI: 10.1016/J.Biopsych.2017.03.005  1
2017 Ide JS, Zhornitsky S, Hu S, Zhang S, Krystal JH, Li CR. Sex differences in the interacting roles of impulsivity and positive alcohol expectancy in problem drinking: A structural brain imaging study. Neuroimage. Clinical. 14: 750-759. PMID 28413777 DOI: 10.1016/J.Nicl.2017.03.015  1
2017 Esterlis I, DellaGioia N, Pietrzak RH, Matuskey D, Nabulsi N, Abdallah CG, Yang J, Pittenger C, Sanacora G, Krystal JH, Parsey RV, Carson RE, DeLorenzo C. Ketamine-induced reduction in mGluR5 availability is associated with an antidepressant response: an [(11)C]ABP688 and PET imaging study in depression. Molecular Psychiatry. PMID 28397841 DOI: 10.1038/Mp.2017.58  1
2017 Wisco BE, Marx BP, May CL, Martini B, Krystal JH, Southwick SM, Pietrzak RH. Moral injury in U.S. combat veterans: Results from the national health and resilience in veterans study. Depression and Anxiety. PMID 28370818 DOI: 10.1002/Da.22614  1
2017 Chekroud AM, Loho H, Krystal JH. Mental illness and mental health. The Lancet. Psychiatry. 4: 276-277. PMID 28347431 DOI: 10.1016/S2215-0366(17)30088-3  1
2017 Krystal JH, Murray JD, Chekroud AM, Corlett PR, Yang G, Wang XJ, Anticevic A. Computational Psychiatry and the Challenge of Schizophrenia. Schizophrenia Bulletin. PMID 28338845 DOI: 10.1093/Schbul/Sbx025  1
2017 Steine IM, Winje D, Skogen JC, Krystal JH, Milde AM, Bjorvatn B, Nordhus IH, Grønli J, Pallesen S. Posttraumatic symptom profiles among adult survivors of childhood sexual abuse: A longitudinal study. Child Abuse & Neglect. 67: 280-293. PMID 28327414 DOI: 10.1016/J.Chiabu.2017.03.002  1
2017 Wrocklage KM, Averill LA, Cobb Scott J, Averill CL, Schweinsburg B, Trejo M, Roy A, Weisser V, Kelly C, Martini B, Harpaz-Rotem I, Southwick SM, Krystal JH, Abdallah CG. Cortical thickness reduction in combat exposed U.S. veterans with and without PTSD. European Neuropsychopharmacology : the Journal of the European College of Neuropsychopharmacology. PMID 28279623 DOI: 10.1016/J.Euroneuro.2017.02.010  1
2017 Abdallah CG, Wrocklage KM, Averill CL, Akiki T, Schweinsburg B, Roy A, Martini B, Southwick SM, Krystal JH, Scott JC. Anterior hippocampal dysconnectivity in posttraumatic stress disorder: a dimensional and multimodal approach. Translational Psychiatry. 7: e1045. PMID 28244983 DOI: 10.1038/Tp.2017.12  1
2017 Chekroud AM, Gueorguieva R, Krumholz HM, Trivedi MH, Krystal JH, McCarthy G. Reevaluating the Efficacy and Predictability of Antidepressant Treatments: A Symptom Clustering Approach. Jama Psychiatry. PMID 28241180 DOI: 10.1001/Jamapsychiatry.2017.0025  1
2017 Gueorguieva R, Chekroud AM, Krystal JH. Trajectories of relapse in randomised, placebo-controlled trials of treatment discontinuation in major depressive disorder: an individual patient-level data meta-analysis. The Lancet. Psychiatry. PMID 28189575 DOI: 10.1016/S2215-0366(17)30038-X  1
2017 Goldenberg MN, Krystal JH. Undergraduate Neuroscience Majors: A Missed Opportunity for Psychiatry Workforce Development. Academic Psychiatry : the Journal of the American Association of Directors of Psychiatric Residency Training and the Association For Academic Psychiatry. PMID 28188505 DOI: 10.1007/S40596-017-0670-Z  0.01
2017 Krystal JH, Petrakis IL, O'Malley S, Krishnan-Sarin S, Pearlson G, Yoon G. NMDA glutamate receptor antagonism and the heritable risk for alcoholism: new insights from a study of nitrous oxide. The International Journal of Neuropsychopharmacology. PMID 28158462 DOI: 10.1093/Ijnp/Pyw118  1
2017 Steine IM, Winje D, Krystal JH, Bjorvatn B, Milde AM, Grønli J, Nordhus IH, Pallesen S. Cumulative childhood maltreatment and its dose-response relation with adult symptomatology: Findings in a sample of adult survivors of sexual abuse. Child Abuse & Neglect. 65: 99-111. PMID 28131947 DOI: 10.1016/J.Chiabu.2017.01.008  1
2017 Chang F, Xu K, Huang MC, Krystal JH. Alcohol Triggers Reemergence of Ketamine-Like Experience in a Ketamine Ex-User. Journal of Clinical Psychopharmacology. 37: 110-112. PMID 28027112 DOI: 10.1097/Jcp.0000000000000635  1
2017 Zhang X, Hu Y, Justice A, Li B, Wang Z, Zhao H, Krystal J, Xu K. DNA methylation signatures analysis with Illumina Infinitum MethylationEPIC and Infinium Human Methylation 450K BeadChip Protocol Exchange. DOI: 10.1038/Protex.2017.135  1
2017 Akiki T, Averill C, Wrocklage K, Scott JC, Alexander-Bloch A, Southwick S, Krystal J, Abdallah C. 581. The Default Mode Network in Posttraumatic Stress Disorder (PTSD): A Data-Driven Multimodal Approach Biological Psychiatry. 81. DOI: 10.1016/J.Biopsych.2017.02.451  1
2017 Esterlis I, Pietrzak R, DellaGioia N, Matuskey D, Huang H, Krystal J, Duman R, Carson R, Finnema S. 389. In Vivo Evidence of Lower Synaptic Density in Depression and Associated Mood and Cognitive Deficits: A [11C]UCB-J PET Imaging Study Biological Psychiatry. 81. DOI: 10.1016/J.Biopsych.2017.02.406  1
2017 Morey R, Logue M, Rooij Sv, Dennis E, Davis S, Hayes J, Stevens J, Densmore M, Koch S, Korgaonkar M, LeBois L, Peverill M, Jahanshad N, Lagopoulos J, Gueze E, ... ... Krystal J, et al. 87. Volume of Sub-Cortical Structures in Posttraumatic Stress Disorder from Multi-Site Investigation by ENIGMA and PGC Consortia Biological Psychiatry. 81. DOI: 10.1016/J.Biopsych.2017.02.099  1
2017 Davis M, Holmes S, Pietrzak R, DellaGioia N, Nabulsi N, Matuskey D, Southwick S, Carson R, Krystal J, Esterlis I. 18. In Vivo Quantification of mGluR5 Availability in Posttraumatic Stress Disorder Biological Psychiatry. 81. DOI: 10.1016/J.Biopsych.2017.02.029  1
2016 Krystal JH, Abi-Dargham A, Barch DM, Bullmore ET, Carter CS, Geschwind DH, Harrison PJ, Nestler EJ, Stein MB. Biological Psychiatry and Biological Psychiatry: Cognitive Neuroscience and Neuroimaging Adopt Neuroscience-Based Nomenclature. Biological Psychiatry. Cognitive Neuroscience and Neuroimaging. 1: 300-301. PMID 29560862 DOI: 10.1016/J.Bpsc.2016.03.007  1
2016 Abdallah CG, Averill LA, Krystal JH, Southwick SM, Arnsten AF. Glutamate and norepinephrine interaction: Relevance to higher cognitive operations and psychopathology. The Behavioral and Brain Sciences. 39: e201. PMID 28347382 DOI: 10.1017/S0140525X15001727  1
2016 Steine IM, Zayats T, Stansberg C, Pallesen S, Mrdalj J, Håvik B, Soulé J, Haavik J, Milde AM, Skrede S, Murison R, Krystal J, Grønli J. Implication of NOTCH1 gene in susceptibility to anxiety and depression among sexual abuse victims. Translational Psychiatry. 6: e977. PMID 27959334 DOI: 10.1038/Tp.2016.248  1
2016 Averill LA, Purohit P, Averill CL, Boesl MA, Krystal JH, Abdallah CG. Glutamate Dysregulation and Glutamatergic Therapeutics for PTSD: Evidence from Human Studies. Neuroscience Letters. PMID 27916636 DOI: 10.1016/J.Neulet.2016.11.064  1
2016 Kelmendi B, Corlett P, Ranganathan M, D'Souza C, Krystal JH. The role of psychedelics in palliative care reconsidered: A case for psilocybin. Journal of Psychopharmacology (Oxford, England). 30: 1212-1214. PMID 27909173 DOI: 10.1177/0269881116675781  1
2016 Yehuda R, Spiegel D, Southwick S, Davis LL, Neylan TC, Krystal JH. What I have changed my mind about and why. European Journal of Psychotraumatology. 7: 33768. PMID 27837585 DOI: 10.3402/Ejpt.V7.33768  1
2016 Kelmendi B, Adams TG, Yarnell S, Southwick S, Abdallah CG, Krystal JH. PTSD: from neurobiology to pharmacological treatments. European Journal of Psychotraumatology. 7: 31858. PMID 27837583 DOI: 10.3402/Ejpt.V7.31858  1
2016 Isaacs K, Mota NP, Tsai J, Harpaz-Rotem I, Cook JM, Kirwin PD, Krystal JH, Southwick SM, Pietrzak RH. Psychological resilience in U.S. military veterans: A 2-year, nationally representative prospective cohort study. Journal of Psychiatric Research. 84: 301-309. PMID 27814502 DOI: 10.1016/J.Jpsychires.2016.10.017  1
2016 Khlestova E, Johnson JW, Krystal JH, Lisman J. The Role of GluN2C-Containing NMDA Receptors in Ketamine's Psychotogenic Action and in Schizophrenia Models. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 36: 11151-11157. PMID 27807157 DOI: 10.1523/Jneurosci.1203-16.2016  0.01
2016 Starc M, Murray JD, Santamauro N, Savic A, Diehl C, Cho YT, Srihari V, Morgan PT, Krystal JH, Wang XJ, Repovs G, Anticevic A. Schizophrenia is associated with a pattern of spatial working memory deficits consistent with cortical disinhibition. Schizophrenia Research. PMID 27745755 DOI: 10.1016/J.Schres.2016.10.011  1
2016 Yang GJ, Murray JD, Glasser M, Pearlson GD, Krystal JH, Schleifer C, Repovs G, Anticevic A. Altered Global Signal Topography in Schizophrenia. Cerebral Cortex (New York, N.Y. : 1991). PMID 27702810 DOI: 10.1093/Cercor/Bhw297  1
2016 Steiner JL, Anez-Nava L, Baranoski M, Cole R, Davidson L, Delphin-Rittmon M, Dike C, DiLeo PJ, Duman RS, Kirk T, Krystal J, Malison RT, Rohrbaugh RM, Sernyak MJ, Srihari V, et al. The Connecticut Mental Health Center: Celebrating 50 Years of a Successful Partnership Between the State and Yale University. Psychiatric Services (Washington, D.C.). appips201600373. PMID 27691379 DOI: 10.1176/Appi.Ps.201600373  1
2016 Watkins LE, Harpaz-Rotem I, Sippel LM, Krystal JH, Southwick SM, Pietrzak RH. Hostility and telomere shortening among U.S. military veterans: Results from the National Health and Resilience in Veterans Study. Psychoneuroendocrinology. 74: 251-257. PMID 27689898 DOI: 10.1016/J.Psyneuen.2016.09.006  1
2016 Mukamal KJ, Clowry CM, Murray MM, Hendriks HF, Rimm EB, Sink KM, Adebamowo CA, Dragsted LO, Lapinski PS, Lazo M, Krystal JH. Moderate Alcohol Consumption and Chronic Disease: The Case for a Long-Term Trial. Alcoholism, Clinical and Experimental Research. PMID 27688006 DOI: 10.1111/Acer.13231  1
2016 Zhang X, Justice AC, Hu Y, Wang Z, Zhao H, Wang G, Johnson EO, Emu B, Sutton RE, Krystal JH, Xu K. Epigenome-wide differential DNA methylation between HIV-infected and uninfected individuals. Epigenetics. 1-11. PMID 27672717 DOI: 10.1080/15592294.2016.1221569  1
2016 Kort NS, Ford JM, Roach BJ, Gunduz-Bruce H, Krystal JH, Jaeger J, Reinhart RM, Mathalon DH. Role of N-Methyl D-Aspartate Receptors in Action-Based Predictive Coding Deficits in Schizophrenia. Biological Psychiatry. PMID 27647218 DOI: 10.1016/J.Biopsych.2016.06.019  1
2016 Pietrzak RH, Zhu Y, Slade MD, Qi Q, Krystal JH, Southwick SM, Levy BR. Association Between Negative Age Stereotypes and Accelerated Cellular Aging: Evidence from Two Cohorts of Older Adults. Journal of the American Geriatrics Society. PMID 27641354 DOI: 10.1111/Jgs.14452  1
2016 Wisco BE, Marx BP, Miller MW, Wolf EJ, Mota NP, Krystal JH, Southwick SM, Pietrzak RH. Probable Posttraumatic Stress Disorder in the US Veteran Population According to DSM-5: Results From the National Health and Resilience in Veterans Study. The Journal of Clinical Psychiatry. PMID 27631148 DOI: 10.4088/Jcp.15M10188  1
2016 Krystal JH, Bugno R. Biological Psychiatry: We're Just Getting Started! Biological Psychiatry. 80: 500-1. PMID 27601337 DOI: 10.1016/J.Biopsych.2016.06.024  0.01
2016 Sippel LM, Mota NP, Kachadourian LK, Krystal JH, Southwick SM, Harpaz-Rotem I, Pietrzak RH. The burden of hostility in U.S. Veterans: Results from the National Health and Resilience in Veterans Study. Psychiatry Research. 243: 421-430. PMID 27450745 DOI: 10.1016/J.Psychres.2016.06.040  1
2016 Gerin MI, Fichtenholtz H, Roy A, Walsh CJ, Krystal JH, Southwick S, Hampson M. Real-Time fMRI Neurofeedback with War Veterans with Chronic PTSD: A Feasibility Study. Frontiers in Psychiatry. 7: 111. PMID 27445868 DOI: 10.3389/Fpsyt.2016.00111  1
2016 Heinz A, Voss M, Lawrie SM, Mishara A, Bauer M, Gallinat J, Juckel G, Lang U, Rapp M, Falkai P, Strik W, Krystal J, Abi-Dargham A, Galderisi S. Shall we really say goodbye to first rank symptoms? European Psychiatry : the Journal of the Association of European Psychiatrists. 37: 8-13. PMID 27429167 DOI: 10.1016/J.Eurpsy.2016.04.010  1
2016 Scott JC, Woods SP, Wrocklage KM, Schweinsburg BC, Southwick SM, Krystal JH. Prospective Memory in Posttraumatic Stress Disorder. Journal of the International Neuropsychological Society : Jins. 1-11. PMID 27353125 DOI: 10.1017/S1355617716000564  1
2016 Krystal JH, Abi-Dargham A, Akbarian S, Arnsten AF, Barch DM, Bearden CE, Braff DL, Brown ES, Bullmore ET, Carlezon WA, Carter CS, Cook EH, Daskalakis ZJ, DiLeone RJ, Duman RS, et al. Constance E. Lieber, Theodore R. Stanley, and the Enduring Impact of Philanthropy on Psychiatry Research. Biological Psychiatry. 80: 84-6. PMID 27346079 DOI: 10.1016/J.Biopsych.2016.05.004  1
2016 Hodgson K, Almasy L, Knowles EE, Kent JW, Curran JE, Dyer TD, Göring HH, Olvera RL, Fox PT, Pearlson GD, Krystal JH, Duggirala R, Blangero J, Glahn DC. Genome-wide significant loci for addiction and anxiety. European Psychiatry : the Journal of the Association of European Psychiatrists. 36: 47-54. PMID 27318301 DOI: 10.1016/J.Eurpsy.2016.03.004  1
2016 Otto MW, Pollack MH, Dowd SM, Hofmann SG, Pearlson G, Szuhany KL, Gueorguieva R, Krystal JH, Simon NM, Tolin DF. RANDOMIZED TRIAL OF D-CYCLOSERINE ENHANCEMENT OF COGNITIVE-BEHAVIORAL THERAPY FOR PANIC DISORDER. Depression and Anxiety. PMID 27315514 DOI: 10.1002/Da.22531  1
2016 Krystal JH, Abi-Dargham A, Barch DM, Bullmore ET, Carter CS, Geschwind DH, Harrison PJ, Nestler EJ, Stein MB. Biological Psychiatry and Biological Psychiatry: Cognitive Neuroscience and Neuroimaging Adopt Neuroscience-Based Nomenclature. Biological Psychiatry. 80: 2-3. PMID 27312230 DOI: 10.1016/J.Biopsych.2016.03.2103  1
2016 Mota NP, Tsai J, Sareen J, Marx BP, Wisco BE, Harpaz-Rotem I, Southwick SM, Krystal JH, Pietrzak RH. High burden of subthreshold DSM-5 post-traumatic stress disorder in U.S. military veterans. World Psychiatry : Official Journal of the World Psychiatric Association (Wpa). 15: 185-186. PMID 27265715 DOI: 10.1002/Wps.20313  1
2016 Murrough JW, Abdallah CG, Anticevic A, Collins KA, Geha P, Averill LA, Schwartz J, DeWilde KE, Averill C, Jia-Wei Yang G, Wong E, Tang CY, Krystal JH, Iosifescu DV, Charney DS. Reduced global functional connectivity of the medial prefrontal cortex in major depressive disorder. Human Brain Mapping. PMID 27144347 DOI: 10.1002/Hbm.23235  1
2016 Watkins LE, Han S, Harpaz-Rotem I, Mota NP, Southwick SM, Krystal JH, Gelernter J, Pietrzak RH. FKBP5 polymorphisms, childhood abuse, and PTSD symptoms: Results from the National Health and Resilience in Veterans Study. Psychoneuroendocrinology. 69: 98-105. PMID 27078785 DOI: 10.1016/J.Psyneuen.2016.04.001  1
2016 Abdallah CG, Adams TG, Kelmendi B, Esterlis I, Sanacora G, Krystal JH. KETAMINE'S MECHANISM OF ACTION: A PATH TO RAPID-ACTING ANTIDEPRESSANTS. Depression and Anxiety. PMID 27062302 DOI: 10.1002/Da.22501  1
2016 Fuehrlein BS, Mota N, Arias AJ, Trevisan LA, Kachadourian LK, Krystal JH, Southwick SM, Pietrzak RH. The burden of alcohol use disorders in U.S. Military veterans: results from the national health and resilience in veterans study. Addiction (Abingdon, England). PMID 27061707 DOI: 10.1111/Add.13423  1
2016 Mota N, Tsai J, Kirwin PD, Harpaz-Rotem I, Krystal JH, Southwick SM, Pietrzak RH. Late-life exacerbation of PTSD symptoms in US veterans: results from the National Health and Resilience in Veterans Study. The Journal of Clinical Psychiatry. 77: 348-354. PMID 27046308 DOI: 10.4088/Jcp.15M10101  1
2016 Rich AM, Cho YT, Tang Y, Savic A, Krystal JH, Wang F, Xu K, Anticevic A. Amygdala volume is reduced in early course schizophrenia. Psychiatry Research. 250: 50-60. PMID 27035063 DOI: 10.1016/J.Pscychresns.2016.02.006  1
2016 Duman RS, Aghajanian GK, Sanacora G, Krystal JH. Synaptic plasticity and depression: new insights from stress and rapid-acting antidepressants. Nature Medicine. 22: 238-49. PMID 26937618 DOI: 10.1038/Nm.4050  1
2016 Wrocklage KM, Schweinsburg BC, Krystal JH, Trejo M, Roy A, Weisser V, Moore TM, Southwick SM, Scott JC. Neuropsychological Functioning in Veterans with Posttraumatic Stress Disorder: Associations with Performance Validity, Comorbidities, and Functional Outcomes. Journal of the International Neuropsychological Society : Jins. 1-13. PMID 26892753 DOI: 10.1017/S1355617716000059  1
2016 Krystal JH, Pietrzak RH, Rosenheck RA, Cramer JA, Vessicchio J, Jones KM, Huang GD, Vertrees JE, Collins J, Krystal AD. Sleep disturbance in chronic military-related PTSD: clinical impact and response to adjunctive risperidone in the Veterans Affairs Cooperative Study #504. The Journal of Clinical Psychiatry. PMID 26890894 DOI: 10.4088/Jcp.14M09585  1
2016 Krystal JH. Neuroethology as a translational neuroscience strategy in the era of the NIMH Research Domain Criteria. Psychophysiology. 53: 364-6. PMID 26877127 DOI: 10.1111/Psyp.12465  0.01
2016 Southwick SM, Sippel L, Krystal J, Charney D, Mayes L, Pietrzak R. Why are some individuals more resilient than others: the role of social support. World Psychiatry : Official Journal of the World Psychiatric Association (Wpa). 15: 77-9. PMID 26833614 DOI: 10.1002/Wps.20282  1
2016 Hu S, Zhang S, Chao HH, Krystal JH, Li CR. Association of Drinking Problems and Duration of Alcohol Use to Inhibitory Control in Nondependent Young Adult Social Drinkers. Alcoholism, Clinical and Experimental Research. PMID 26833431 DOI: 10.1111/Acer.12964  1
2016 Chekroud AM, Zotti RJ, Shehzad Z, Gueorguieva R, Johnson MK, Trivedi MH, Cannon TD, Krystal JH, Corlett PR. Cross-trial prediction of treatment outcome in depression: a machine learning approach. The Lancet. Psychiatry. PMID 26803397 DOI: 10.1016/S2215-0366(15)00471-X  1
2016 Cavus I, Widi GA, Duckrow RB, Zaveri H, Kennard JT, Krystal J, Spencer DD. 50 Hz hippocampal stimulation in refractory epilepsy: Higher level of basal glutamate predicts greater release of glutamate. Epilepsia. PMID 26749134 DOI: 10.1111/Epi.13269  1
2016 Chekroud A, Zotti R, Shehzad Z, Gueorguieva R, Johnson M, Trivedi M, Cannon T, Krystal J, Corlett P. Cross-trial prediction of treatment outcomes in depression F1000research. 5. DOI: 10.7490/F1000Research.1111949.1  1
2016 Krystal JH, Sanacora G, Abdallah C, Duman R. Speaker 4: John Krystal, USA. The International Journal of Neuropsychopharmacology. 19: 19-19. DOI: 10.1093/Ijnp/Pyw042.052  1
2016 Krystal JH, Anticevic A, Yang G, Driesen N, Cortes-Briones J, Stone JM, Wang X, Murray JD. Speaker 3: John Krystal, USA The International Journal of Neuropsychopharmacology. 19: 5-5. DOI: 10.1093/Ijnp/Pyw042.007  1
2015 Southwick SM, Pietrzak RH, Charney DS, Krystal JH. Resilience: The role of accurate appraisal, thresholds, and socioenvironmental factors. The Behavioral and Brain Sciences. 38: e122. PMID 26786005 DOI: 10.1017/S0140525X14001708  1
2015 Yang GJ, Murray JD, Wang XJ, Glahn DC, Pearlson GD, Repovs G, Krystal JH, Anticevic A. Functional hierarchy underlies preferential connectivity disturbances in schizophrenia. Proceedings of the National Academy of Sciences of the United States of America. PMID 26699491 DOI: 10.1073/Pnas.1508436113  1
2015 Krystal JH, Anticevic A. Toward Illness Phase-Specific Pharmacotherapy for Schizophrenia. Biological Psychiatry. 78: 738-40. PMID 26542740 DOI: 10.1016/J.Biopsych.2015.08.017  1
2015 Guille C, Zhao Z, Krystal J, Nichols B, Brady K, Sen S. Web-Based Cognitive Behavioral Therapy Intervention for the Prevention of Suicidal Ideation in Medical Interns: A Randomized Clinical Trial. Jama Psychiatry. 1-7. PMID 26535958 DOI: 10.1001/Jamapsychiatry.2015.1880  1
2015 Licznerski P, Duric V, Banasr M, Alavian KN, Ota KT, Kang HJ, Jonas EA, Ursano R, Krystal JH, Duman RS. Decreased SGK1 Expression and Function Contributes to Behavioral Deficits Induced by Traumatic Stress. Plos Biology. 13: e1002282. PMID 26506154 DOI: 10.1371/Journal.Pbio.1002282  1
2015 Yoon G, Pittman B, Limoncelli D, Krystal JH, Petrakis IL. Familial Alcoholism Risk and the Ratio of Stimulant to Sedative Effects of Ketamine. Biological Psychiatry. PMID 26475672 DOI: 10.1016/J.Biopsych.2015.09.006  1
2015 Corbin WR, Papova A, Morean ME, O'Malley SS, Krishnan-Sarin S, Abi-Dargham A, Anticevic A, Pearlson G, Petrakis I, Pittman BP, Krystal JH. Integrating Acquired Preparedness and Dual Process Models of Risk for Heavy Drinking and Related Problems. Psychology of Addictive Behaviors : Journal of the Society of Psychologists in Addictive Behaviors. PMID 26348221 DOI: 10.1037/Adb0000093  1
2015 Zuo L, Tan Y, Zhang X, Wang X, Krystal J, Tabakoff B, Zhong C, Luo X. A New Genomewide Association Meta-Analysis of Alcohol Dependence. Alcoholism, Clinical and Experimental Research. PMID 26173551 DOI: 10.1111/Acer.12786  1
2015 Stone J, Kotoula V, Dietrich C, De Simoni S, Krystal JH, Mehta MA. Perceptual distortions and delusional thinking following ketamine administration are related to increased pharmacological MRI signal changes in the parietal lobe. Journal of Psychopharmacology (Oxford, England). 29: 1025-8. PMID 26152321 DOI: 10.1177/0269881115592337  1
2015 Zuo L, Zhang CK, Sayward FG, Cheung KH, Wang K, Krystal JH, Zhao H, Luo X. Gene-based and pathway-based genome-wide association study of alcohol dependence. Shanghai Archives of Psychiatry. 27: 111-8. PMID 26120261 DOI: 10.11919/J.Issn.1002-0829.215031  1
2015 Zuo L, Saba L, Lin X, Tan Y, Wang K, Krystal JH, Tabakoff B, Luo X. Significant association between rare IPO11-HTR1A variants and attention deficit hyperactivity disorder in Caucasians. American Journal of Medical Genetics. Part B, Neuropsychiatric Genetics : the Official Publication of the International Society of Psychiatric Genetics. PMID 26079129 DOI: 10.1002/Ajmg.B.32329  1
2015 Chekroud AM, Krystal JH. Personalised pharmacotherapy: an interim solution for antidepressant treatment? Bmj (Clinical Research Ed.). 350: h2502. PMID 25976040 DOI: 10.1136/Bmj.H2502  1
2015 Krystal JH, Carter CS. Introducing a new journal: biological psychiatry: cognitive neuroscience and neuroimaging. Biological Psychiatry. 77: 922. PMID 25959562 DOI: 10.1016/J.Biopsych.2015.04.009  1
2015 Ahn KH, Sewell A, Elander J, Pittman B, Ranganathan M, Gunduz-Bruce H, Krystal J, D'Souza DC. Role of GABA Deficit in Sensitivity to the Psychotomimetic Effects of Amphetamine. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. PMID 25953357 DOI: 10.1038/Npp.2015.132  1
2015 Krystal JH, Stossel S, Krystal AD. Restricting Benzodiazepines to Short-Term Prescription. Jama Psychiatry. 72: 734-5. PMID 25923129 DOI: 10.1001/Jamapsychiatry.2015.0351  1
2015 Abdallah CG, Averill LA, Krystal JH. Ketamine as a promising prototype for a new generation of rapid-acting antidepressants. Annals of the New York Academy of Sciences. 1344: 66-77. PMID 25727103 DOI: 10.1111/Nyas.12718  1
2015 Pietrzak RH, Averill LA, Abdallah CG, Neumeister A, Krystal JH, Levy I, Harpaz-Rotem I. Amygdala-hippocampal volume and the phenotypic heterogeneity of posttraumatic stress disorder: a cross-sectional study. Jama Psychiatry. 72: 396-8. PMID 25692480 DOI: 10.1001/Jamapsychiatry.2014.2470  1
2015 Krystal JH. Deconstructing N-methyl-d-aspartate glutamate receptor contributions to cortical circuit functions to construct better hypotheses about the pathophysiology of schizophrenia. Biological Psychiatry. 77: 508-10. PMID 25687430 DOI: 10.1016/J.Biopsych.2014.10.010  1
2015 Krishnan-Sarin S, O'Malley SS, Franco N, Cavallo DA, Morean M, Shi J, Pittman B, Krystal JH. N-methyl-D-aspartate receptor antagonism has differential effects on alcohol craving and drinking in heavy drinkers. Alcoholism, Clinical and Experimental Research. 39: 300-7. PMID 25664775 DOI: 10.1111/Acer.12619  1
2015 Krystal JH, O'Malley SS. From translational neuroscience to personalized medicine. Alcoholism, Clinical and Experimental Research. 39: 585-6. PMID 25656652 DOI: 10.1111/Acer.12667  1
2015 Anticevic A, Hu X, Xiao Y, Hu J, Li F, Bi F, Cole MW, Savic A, Yang GJ, Repovs G, Murray JD, Wang XJ, Huang X, Lui S, Krystal JH, et al. Early-course unmedicated schizophrenia patients exhibit elevated prefrontal connectivity associated with longitudinal change. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 35: 267-86. PMID 25568120 DOI: 10.1523/Jneurosci.2310-14.2015  1
2015 Tsai J, Harpaz-Rotem I, Armour C, Southwick SM, Krystal JH, Pietrzak RH. Dimensional structure of DSM-5 posttraumatic stress disorder symptoms: results from the National Health and Resilience in Veterans Study. The Journal of Clinical Psychiatry. 76: 546-53. PMID 25562376 DOI: 10.4088/Jcp.14M09091  1
2015 Xu K, Krystal JH, Ning Y, Chen da C, He H, Wang D, Ke X, Zhang X, Ding Y, Liu Y, Gueorguieva R, Wang Z, Limoncelli D, Pietrzak RH, Petrakis IL, et al. Preliminary analysis of positive and negative syndrome scale in ketamine-associated psychosis in comparison with schizophrenia. Journal of Psychiatric Research. 61: 64-72. PMID 25560772 DOI: 10.1016/J.Jpsychires.2014.12.012  1
2015 Krystal JH. Biological psychiatry: looking good! Biological Psychiatry. 77: 2. PMID 25483341 DOI: 10.1016/J.Biopsych.2014.10.007  1
2015 Saricicek A, Chen J, Planeta B, Ruf B, Subramanyam K, Maloney K, Matuskey D, Labaree D, Deserno L, Neumeister A, Krystal JH, Gallezot JD, Huang Y, Carson RE, Bhagwagar Z. Test-retest reliability of the novel 5-HT1B receptor PET radioligand [11C]P943. European Journal of Nuclear Medicine and Molecular Imaging. 42: 468-77. PMID 25427881 DOI: 10.1007/S00259-014-2958-5  1
2015 Scott JC, Matt GE, Wrocklage KM, Crnich C, Jordan J, Southwick SM, Krystal JH, Schweinsburg BC. A quantitative meta-analysis of neurocognitive functioning in posttraumatic stress disorder. Psychological Bulletin. 141: 105-40. PMID 25365762 DOI: 10.1037/A0038039  1
2015 Abdallah CG, Sanacora G, Duman RS, Krystal JH. Ketamine and rapid-acting antidepressants: a window into a new neurobiology for mood disorder therapeutics. Annual Review of Medicine. 66: 509-23. PMID 25341010 DOI: 10.1146/Annurev-Med-053013-062946  1
2015 Anticevic A, Corlett PR, Cole MW, Savic A, Gancsos M, Tang Y, Repovs G, Murray JD, Driesen NR, Morgan PT, Xu K, Wang F, Krystal JH. N-methyl-D-aspartate receptor antagonist effects on prefrontal cortical connectivity better model early than chronic schizophrenia. Biological Psychiatry. 77: 569-80. PMID 25281999 DOI: 10.1016/J.Biopsych.2014.07.022  1
2015 DeLorenzo C, DellaGioia N, Bloch M, Sanacora G, Nabulsi N, Abdallah C, Yang J, Wen R, Mann JJ, Krystal JH, Parsey RV, Carson RE, Esterlis I. In vivo ketamine-induced changes in [¹¹C]ABP688 binding to metabotropic glutamate receptor subtype 5. Biological Psychiatry. 77: 266-75. PMID 25156701 DOI: 10.1016/J.Biopsych.2014.06.024  1
2015 Anticevic A, Savic A, Repovs G, Yang G, McKay DR, Sprooten E, Knowles EE, Krystal JH, Pearlson GD, Glahn DC. Ventral anterior cingulate connectivity distinguished nonpsychotic bipolar illness from psychotic bipolar disorder and schizophrenia. Schizophrenia Bulletin. 41: 133-43. PMID 24782562 DOI: 10.1093/Schbul/Sbu051  1
2015 Ahn KH, Sewell A, Elander J, Pittman B, Ranganathan M, Gunduz-Bruce H, Krystal J, D'Souza DC. Role of GABA Deficit in Sensitivity to the Psychotomimetic Effects of Amphetamine Neuropsychopharmacology. DOI: 10.1038/npp.2015.132  1
2014 Cosgrove KP, McKay R, Esterlis I, Kloczynski T, Perkins E, Bois F, Pittman B, Lancaster J, Glahn DC, O'Malley S, Carson RE, Krystal JH. Tobacco smoking interferes with GABAA receptor neuroadaptations during prolonged alcohol withdrawal. Proceedings of the National Academy of Sciences of the United States of America. 111: 18031-6. PMID 25453062 DOI: 10.1073/Pnas.1413947111  1
2014 Pietrzak RH, Rosenheck RA, Cramer JA, Vessichio JC, Tsai J, Southwick SM, Krystal JH. Elucidating the transdiagnostic dimensional structure of trauma-related psychopathology: Findings from VA cooperative study 504 - risperidone treatment for military service related chronic post traumatic stress disorder. Journal of Affective Disorders. 172: 331-336. PMID 25451434 DOI: 10.1016/J.Jad.2014.10.025  1
2014 Wang XJ, Krystal JH. Computational psychiatry. Neuron. 84: 638-54. PMID 25442941 DOI: 10.1016/j.neuron.2014.10.018  1
2014 Abdallah CG, Jiang L, De Feyter HM, Fasula M, Krystal JH, Rothman DL, Mason GF, Sanacora G. Glutamate metabolism in major depressive disorder. The American Journal of Psychiatry. 171: 1320-7. PMID 25073688 DOI: 10.1176/Appi.Ajp.2014.14010067  1
2014 Gallezot JD, Esterlis I, Bois F, Zheng MQ, Lin SF, Kloczynski T, Krystal JH, Huang Y, Sabri O, Carson RE, Cosgrove KP. Evaluation of the sensitivity of the novel α4β2* nicotinic acetylcholine receptor PET radioligand 18F-(-)-NCFHEB to increases in synaptic acetylcholine levels in rhesus monkeys. Synapse (New York, N.Y.). 68: 556-64. PMID 25043426 DOI: 10.1002/Syn.21767  1
2014 Morean ME, DeMartini KS, Leeman RF, Pearlson GD, Anticevic A, Krishnan-Sarin S, Krystal JH, O'Malley SS. Psychometrically improved, abbreviated versions of three classic measures of impulsivity and self-control. Psychological Assessment. 26: 1003-20. PMID 24885848 DOI: 10.1037/Pas0000003  1
2014 Yang GJ, Murray JD, Repovs G, Cole MW, Savic A, Glasser MF, Pittenger C, Krystal JH, Wang XJ, Pearlson GD, Glahn DC, Anticevic A. Altered global brain signal in schizophrenia. Proceedings of the National Academy of Sciences of the United States of America. 111: 7438-43. PMID 24799682 DOI: 10.1073/Pnas.1405289111  1
2014 Krystal JH, State MW. Psychiatric disorders: diagnosis to therapy. Cell. 157: 201-14. PMID 24679536 DOI: 10.1016/J.Cell.2014.02.042  1
2014 Stefanovics EA, Krystal JH, Rosenheck RA. Symptom structure and severity: a comparison of responses to the positive and negative syndrome scale (PANSS) between patients with PTSD or schizophrenia. Comprehensive Psychiatry. 55: 887-95. PMID 24602497 DOI: 10.1016/J.Comppsych.2014.01.014  1
2014 Castellan Baldan L, Williams KA, Gallezot JD, Pogorelov V, Rapanelli M, Crowley M, Anderson GM, Loring E, Gorczyca R, Billingslea E, Wasylink S, Panza KE, Ercan-Sencicek AG, Krusong K, Leventhal BL, ... ... Krystal JH, et al. Histidine decarboxylase deficiency causes tourette syndrome: parallel findings in humans and mice. Neuron. 81: 77-90. PMID 24411733 DOI: 10.1016/J.Neuron.2013.10.052  1
2014 Leatherman SM, Liang MH, Krystal JH, Lew RA, Valley D, Thwin SS, Rosenheck RA. Differences in treatment effect among clinical subgroups in a randomized clinical trial of long-acting injectable risperidone and oral antipsychotics in unstable chronic schizophrenia. The Journal of Nervous and Mental Disease. 202: 13-7. PMID 24375206 DOI: 10.1097/Nmd.0000000000000069  1
2014 Anticevic A, Tang Y, Cho YT, Repovs G, Cole MW, Savic A, Wang F, Krystal JH, Xu K. Amygdala connectivity differs among chronic, early course, and individuals at risk for developing schizophrenia. Schizophrenia Bulletin. 40: 1105-16. PMID 24366718 DOI: 10.1093/Schbul/Sbt165  1
2014 Boggs DL, Carlson J, Cortes-Briones J, Krystal JH, D'Souza DC. Going up in smoke? A review of nAChRs-based treatment strategies for improving cognition in schizophrenia. Current Pharmaceutical Design. 20: 5077-92. PMID 24345265 DOI: 10.2174/1381612819666131216121019  1
2014 Anticevic A, Hu S, Zhang S, Savic A, Billingslea E, Wasylink S, Repovs G, Cole MW, Bednarski S, Krystal JH, Bloch MH, Li CS, Pittenger C. Global resting-state functional magnetic resonance imaging analysis identifies frontal cortex, striatal, and cerebellar dysconnectivity in obsessive-compulsive disorder. Biological Psychiatry. 75: 595-605. PMID 24314349 DOI: 10.1016/J.Biopsych.2013.10.021  1
2014 Xie P, Kranzler HR, Krystal JH, Farrer LA, Zhao H, Gelernter J. Deep resequencing of 17 glutamate system genes identifies rare variants in DISC1 and GRIN2B affecting risk of opioid dependence. Addiction Biology. 19: 955-64. PMID 23855403 DOI: 10.1111/Adb.12072  1
2014 Anticevic A, Cole MW, Repovs G, Murray JD, Brumbaugh MS, Winkler AM, Savic A, Krystal JH, Pearlson GD, Glahn DC. Characterizing thalamo-cortical disturbances in schizophrenia and bipolar illness. Cerebral Cortex (New York, N.Y. : 1991). 24: 3116-30. PMID 23825317 DOI: 10.1093/Cercor/Bht165  1
2014 Murray JD, Anticevic A, Gancsos M, Ichinose M, Corlett PR, Krystal JH, Wang XJ. Linking microcircuit dysfunction to cognitive impairment: effects of disinhibition associated with schizophrenia in a cortical working memory model. Cerebral Cortex (New York, N.Y. : 1991). 24: 859-72. PMID 23203979 DOI: 10.1093/Cercor/Bhs370  1
2013 Anticevic A, Cole MW, Repovs G, Savic A, Driesen NR, Yang G, Cho YT, Murray JD, Glahn DC, Wang XJ, Krystal JH. Connectivity, pharmacology, and computation: toward a mechanistic understanding of neural system dysfunction in schizophrenia. Frontiers in Psychiatry. 4: 169. PMID 24399974 DOI: 10.3389/Fpsyt.2013.00169  1
2013 Pietrzak RH, Gallezot JD, Ding YS, Henry S, Potenza MN, Southwick SM, Krystal JH, Carson RE, Neumeister A. Association of posttraumatic stress disorder with reduced in vivo norepinephrine transporter availability in the locus coeruleus. Jama Psychiatry. 70: 1199-205. PMID 24048210 DOI: 10.1001/Jamapsychiatry.2013.399  1
2013 Krystal JH. Biological psychiatry: raising the bar. Biological Psychiatry. 74: 476-7. PMID 24034363 DOI: 10.1016/J.Biopsych.2013.07.034  1
2013 Holmes A, Spanagel R, Krystal JH. Glutamatergic targets for new alcohol medications. Psychopharmacology. 229: 539-54. PMID 23995381 DOI: 10.1007/S00213-013-3226-2  1
2013 Zuo L, Wang K, Zhang X, Pan X, Wang G, Krystal JH, Zhang H, Luo X. Sex chromosome-wide association analysis suggested male-specific risk genes for alcohol dependence. Psychiatric Genetics. 23: 233-8. PMID 23907288 DOI: 10.1097/Ypg.0B013E328364B8C7  1
2013 Driesen NR, McCarthy G, Bhagwagar Z, Bloch MH, Calhoun VD, D'Souza DC, Gueorguieva R, He G, Leung HC, Ramani R, Anticevic A, Suckow RF, Morgan PT, Krystal JH. The impact of NMDA receptor blockade on human working memory-related prefrontal function and connectivity. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 38: 2613-22. PMID 23856634 DOI: 10.1038/Npp.2013.170  1
2013 Zuo L, Wang KS, Zhang XY, Li CS, Zhang F, Wang X, Chen W, Gao G, Zhang H, Krystal JH, Luo X. Rare SERINC2 variants are specific for alcohol dependence in individuals of European descent. Pharmacogenetics and Genomics. 23: 395-402. PMID 23778322 DOI: 10.1097/Fpc.0B013E328362F9F2  1
2013 Corlett PR, Cambridge V, Gardner JM, Piggot JS, Turner DC, Everitt JC, Arana FS, Morgan HL, Milton AL, Lee JL, Aitken MR, Dickinson A, Everitt BJ, Absalom AR, Adapa R, ... ... Krystal JH, et al. Ketamine effects on memory reconsolidation favor a learning model of delusions. Plos One. 8: e65088. PMID 23776445 DOI: 10.1371/Journal.Pone.0065088  1
2013 Zuo L, Saba L, Wang K, Zhang X, Krystal JH, Tabakoff B, Luo X. Exome-wide association study of replicable nonsynonymous variants conferring risk for alcohol dependence. Journal of Studies On Alcohol and Drugs. 74: 622-5. PMID 23739027 DOI: 10.15288/Jsad.2013.74.622  1
2013 Krystal JH, Sanacora G, Duman RS. Rapid-acting glutamatergic antidepressants: the path to ketamine and beyond. Biological Psychiatry. 73: 1133-41. PMID 23726151 DOI: 10.1016/J.Biopsych.2013.03.026  1
2013 DeVito EE, Meda SA, Jiantonio R, Potenza MN, Krystal JH, Pearlson GD. Neural correlates of impulsivity in healthy males and females with family histories of alcoholism. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 38: 1854-63. PMID 23584260 DOI: 10.1038/Npp.2013.92  1
2013 Jiang L, Gulanski BI, De Feyter HM, Weinzimer SA, Pittman B, Guidone E, Koretski J, Harman S, Petrakis IL, Krystal JH, Mason GF. Increased brain uptake and oxidation of acetate in heavy drinkers. The Journal of Clinical Investigation. 123: 1605-14. PMID 23478412 DOI: 10.1172/Jci65153  1
2013 Zuo L, Wang K, Zhang XY, Pan X, Wang G, Tan Y, Zhong C, Krystal JH, State M, Zhang H, Luo X. Association between common alcohol dehydrogenase gene (ADH) variants and schizophrenia and autism. Human Genetics. 132: 735-43. PMID 23468174 DOI: 10.1007/S00439-013-1277-4  1
2013 Zuo L, Wang K, Zhang XY, Krystal JH, Li CS, Zhang F, Zhang H, Luo X. NKAIN1-SERINC2 is a functional, replicable and genome-wide significant risk gene region specific for alcohol dependence in subjects of European descent. Drug and Alcohol Dependence. 129: 254-64. PMID 23455491 DOI: 10.1016/J.Drugalcdep.2013.02.006  1
2013 Gueorguieva R, Wu R, Krystal JH, Donovan D, O'Malley SS. Temporal patterns of adherence to medications and behavioral treatment and their relationship to patient characteristics and treatment response. Addictive Behaviors. 38: 2119-27. PMID 23435273 DOI: 10.1016/J.Addbeh.2013.01.024  1
2013 Narayanan B, Stevens MC, Jiantonio RE, Krystal JH, Pearlson GD. Effects of memantine on event-related potential, oscillations, and complexity in individuals with and without family histories of alcoholism. Journal of Studies On Alcohol and Drugs. 74: 245-57. PMID 23384372 DOI: 10.15288/Jsad.2013.74.245  1
2013 Driesen NR, McCarthy G, Bhagwagar Z, Bloch M, Calhoun V, D'Souza DC, Gueorguieva R, He G, Ramachandran R, Suckow RF, Anticevic A, Morgan PT, Krystal JH. Relationship of resting brain hyperconnectivity and schizophrenia-like symptoms produced by the NMDA receptor antagonist ketamine in humans. Molecular Psychiatry. 18: 1199-204. PMID 23337947 DOI: 10.1038/Mp.2012.194  1
2013 Zuo L, Zhang XY, Wang F, Li CS, Lu L, Ye L, Zhang H, Krystal JH, Deng HW, Luo X. Genome-wide significant association signals in IPO11-HTR1A region specific for alcohol and nicotine codependence. Alcoholism, Clinical and Experimental Research. 37: 730-9. PMID 23216389 DOI: 10.1111/Acer.12032  1
2013 Insel T, Krystal J, Ehlers M. New drug development for cognitive enhancement in mental health: challenges and opportunities. Neuropharmacology. 64: 2-7. PMID 23145450 DOI: 10.1016/J.Neuropharm.2012.07.041  0.08
2013 Fryer SL, Jorgensen KW, Yetter EJ, Daurignac EC, Watson TD, Shanbhag H, Krystal JH, Mathalon DH. Differential brain response to alcohol cue distractors across stages of alcohol dependence. Biological Psychology. 92: 282-91. PMID 23131612 DOI: 10.1016/J.Biopsycho.2012.10.004  1
2013 Woods SW, Walsh BC, Hawkins KA, Miller TJ, Saksa JR, D'Souza DC, Pearlson GD, Javitt DC, McGlashan TH, Krystal JH. Glycine treatment of the risk syndrome for psychosis: report of two pilot studies. European Neuropsychopharmacology : the Journal of the European College of Neuropsychopharmacology. 23: 931-40. PMID 23089076 DOI: 10.1016/J.Euroneuro.2012.09.008  1
2013 Zuo L, Zhang H, Malison RT, Li CS, Zhang XY, Wang F, Lu L, Lu L, Wang X, Krystal JH, Zhang F, Deng HW, Luo X. Rare ADH variant constellations are specific for alcohol dependence. Alcohol and Alcoholism (Oxford, Oxfordshire). 48: 9-14. PMID 23019235 DOI: 10.1093/Alcalc/Ags104  1
2013 Anticevic A, Brumbaugh MS, Winkler AM, Lombardo LE, Barrett J, Corlett PR, Kober H, Gruber J, Repovs G, Cole MW, Krystal JH, Pearlson GD, Glahn DC. Global prefrontal and fronto-amygdala dysconnectivity in bipolar I disorder with psychosis history. Biological Psychiatry. 73: 565-73. PMID 22980587 DOI: 10.1016/J.Biopsych.2012.07.031  1
2013 Pietrzak RH, Henry S, Southwick SM, Krystal JH, Neumeister A. Linking in vivo brain serotonin type 1B receptor density to phenotypic heterogeneity of posttraumatic stress symptomatology. Molecular Psychiatry. 18: 399-401. PMID 22584868 DOI: 10.1038/Mp.2012.60  1
2013 Xu K, Fan N, Wang D, Zhang X, Ke X, Liu Y, He H, Zhou C, Ding Y, Wang L, Krystal J, Ning Y. Characterisation of ketamine use and associated psychotic symptoms in an inpatient Chinese population F1000research. 4. DOI: 10.7490/F1000Research.1093558.1  1
2012 Anticevic A, Cole MW, Murray JD, Corlett PR, Wang XJ, Krystal JH. The role of default network deactivation in cognition and disease. Trends in Cognitive Sciences. 16: 584-92. PMID 23142417 DOI: 10.1016/J.Tics.2012.10.008  1
2012 Anticevic A, Gancsos M, Murray JD, Repovs G, Driesen NR, Ennis DJ, Niciu MJ, Morgan PT, Surti TS, Bloch MH, Ramani R, Smith MA, Wang XJ, Krystal JH, Corlett PR. NMDA receptor function in large-scale anticorrelated neural systems with implications for cognition and schizophrenia. Proceedings of the National Academy of Sciences of the United States of America. 109: 16720-5. PMID 23012427 DOI: 10.1073/Pnas.1208494109  1
2012 Moghaddam B, Krystal JH. Capturing the angel in "angel dust": twenty years of translational neuroscience studies of NMDA receptor antagonists in animals and humans. Schizophrenia Bulletin. 38: 942-9. PMID 22899397 DOI: 10.1093/Schbul/Sbs075  1
2012 Anticevic A, Repovs G, Krystal JH, Barch DM. A broken filter: prefrontal functional connectivity abnormalities in schizophrenia during working memory interference. Schizophrenia Research. 141: 8-14. PMID 22863548 DOI: 10.1016/J.Schres.2012.07.007  1
2012 Bloch MH, Wasylink S, Landeros-Weisenberger A, Panza KE, Billingslea E, Leckman JF, Krystal JH, Bhagwagar Z, Sanacora G, Pittenger C. Effects of ketamine in treatment-refractory obsessive-compulsive disorder. Biological Psychiatry. 72: 964-70. PMID 22784486 DOI: 10.1016/J.Biopsych.2012.05.028  1
2012 Barnett PG, Scott JY, Krystal JH, Rosenheck RA. Cost and cost-effectiveness in a randomized trial of long-acting risperidone for schizophrenia. The Journal of Clinical Psychiatry. 73: 696-702. PMID 22697193 DOI: 10.4088/Jcp.11M07070  1
2012 Nestler EJ, Krystal JH. Planning the new national institute on substance use and addiction disorders. Biological Psychiatry. 72: 166-7. PMID 22683089 DOI: 10.1016/J.Biopsych.2012.05.011  1
2012 Hyatt CJ, Assaf M, Muska CE, Rosen RI, Thomas AD, Johnson MR, Hylton JL, Andrews MM, Reynolds BA, Krystal JH, Potenza MN, Pearlson GD. Reward-related dorsal striatal activity differences between former and current cocaine dependent individuals during an interactive competitive game. Plos One. 7: e34917. PMID 22606228 DOI: 10.1371/Journal.Pone.0034917  1
2012 Krystal JH. Enhancing prolonged exposure therapy for posttraumatic stress disorder with D-cycloserine: further support for treatments that promote experience-dependent neuroplasticity. Biological Psychiatry. 71: 932-4. PMID 22579302 DOI: 10.1016/J.Biopsych.2012.03.031  1
2012 Zuo L, Zhang F, Zhang H, Zhang XY, Wang F, Li CSR, Lu L, Hong J, Krystal J, Deng HW, Luo X. Genome-wide search for replicable risk gene regions in alcohol and nicotine co-dependence American Journal of Medical Genetics, Part B: Neuropsychiatric Genetics. 159: 437-444. PMID 22488850 DOI: 10.1002/Ajmg.B.32047  1
2012 Cavu? I, Reinhart RM, Roach BJ, Gueorguieva R, Teyler TJ, Clapp WC, Ford JM, Krystal JH, Mathalon DH. Impaired visual cortical plasticity in schizophrenia. Biological Psychiatry. 71: 512-20. PMID 22364738 DOI: 10.1016/J.Biopsych.2012.01.013  1
2012 Pietrzak RH, Maruff P, Woodward M, Fredrickson J, Fredrickson A, Krystal JH, Southwick SM, Darby D. Mild worry symptoms predict decline in learning and memory in healthy older adults: a 2-year prospective cohort study. The American Journal of Geriatric Psychiatry : Official Journal of the American Association For Geriatric Psychiatry. 20: 266-75. PMID 22354117 DOI: 10.1097/Jgp.0B013E3182107E24  1
2012 Jamadar S, DeVito EE, Jiantonio RE, Meda SA, Stevens MC, Potenza MN, Krystal JH, Pearlson GD. Memantine, an NMDA receptor antagonist, differentially influences Go/No-Go performance and fMRI activity in individuals with and without a family history of alcoholism. Psychopharmacology. 222: 129-40. PMID 22311382 DOI: 10.1007/S00213-011-2628-2  1
2012 Kaffman A, Krystal JH, Krystal JJ. New frontiers in animal research of psychiatric illness. Methods in Molecular Biology (Clifton, N.J.). 829: 3-30. PMID 22231804 DOI: 10.1007/978-1-61779-458-2_1  1
2012 Stone JM, Dietrich C, Edden R, Mehta MA, De Simoni S, Reed LJ, Krystal JH, Nutt D, Barker GJ. Ketamine effects on brain GABA and glutamate levels with 1H-MRS: relationship to ketamine-induced psychopathology. Molecular Psychiatry. 17: 664-5. PMID 22212598 DOI: 10.1038/Mp.2011.171  1
2012 Steine IM, Krystal JH, Nordhus IH, Bjorvatn B, Harvey AG, Eid J, Grønli J, Milde AM, Pallesen S. Insomnia, nightmare frequency, and nightmare distress in victims of sexual abuse: the role of perceived social support and abuse characteristics. Journal of Interpersonal Violence. 27: 1827-43. PMID 22204947 DOI: 10.1177/0886260511430385  1
2012 Petrakis IL, Ralevski E, Desai N, Trevisan L, Gueorguieva R, Rounsaville B, Krystal JH. Noradrenergic vs serotonergic antidepressant with or without naltrexone for veterans with PTSD and comorbid alcohol dependence. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 37: 996-1004. PMID 22089316 DOI: 10.1038/Npp.2011.283  1
2012 Urban NB, Slifstein M, Meda S, Xu X, Ayoub R, Medina O, Pearlson GD, Krystal JH, Abi-Dargham A. Imaging human reward processing with positron emission tomography and functional magnetic resonance imaging. Psychopharmacology. 221: 67-77. PMID 22052081 DOI: 10.1007/S00213-011-2543-6  1
2012 Gunduz-Bruce H, Reinhart RM, Roach BJ, Gueorguieva R, Oliver S, D'Souza DC, Ford JM, Krystal JH, Mathalon DH. Glutamatergic modulation of auditory information processing in the human brain. Biological Psychiatry. 71: 969-77. PMID 22036036 DOI: 10.1016/J.Biopsych.2011.09.031  1
2012 Zuo L, Gelernter J, Zhang CK, Zhao H, Lu L, Kranzler HR, Malison RT, Li CS, Wang F, Zhang XY, Deng HW, Krystal JH, Zhang F, Luo X. Genome-wide association study of alcohol dependence implicates KIAA0040 on chromosome 1q. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 37: 557-66. PMID 21956439 DOI: 10.1038/Npp.2011.229  1
2012 Gueorguieva R, Wu R, Donovan D, Rounsaville BJ, Couper D, Krystal JH, O'Malley SS. Baseline trajectories of heavy drinking and their effects on postrandomization drinking in the COMBINE Study: empirically derived predictors of drinking outcomes during treatment. Alcohol (Fayetteville, N.Y.). 46: 121-31. PMID 21925828 DOI: 10.1016/J.Alcohol.2011.08.008  1
2012 Gomez R, Behar KL, Watzl J, Weinzimer SA, Gulanski B, Sanacora G, Koretski J, Guidone E, Jiang L, Petrakis IL, Pittman B, Krystal JH, Mason GF. Intravenous ethanol infusion decreases human cortical γ-aminobutyric acid and N-acetylaspartate as measured with proton magnetic resonance spectroscopy at 4 tesla. Biological Psychiatry. 71: 239-46. PMID 21855054 DOI: 10.1016/J.Biopsych.2011.06.026  1
2012 Steine IM, Harvey AG, Krystal JH, Milde AM, Grønli J, Bjorvatn B, Nordhus IH, Eid J, Pallesen S. Sleep disturbances in sexual abuse victims: a systematic review. Sleep Medicine Reviews. 16: 15-25. PMID 21600813 DOI: 10.1016/J.Smrv.2011.01.006  1
2012 Zuo L, Gelernter J, Zhang CK, Zhao H, Lu L, Kranzler HR, Malison RT, Li CSR, Wang F, Zhang XY, Deng HW, Krystal JH, Zhang F, Luo X. Erratum: Genome-Wide Association Study of Alcohol Dependence Implicates KIAA0040 on Chromosome 1q Neuropsychopharmacology. 37: 581-582. DOI: 10.1038/Npp.2011.271  1
2012 Stone J, Dietrich C, Edden R, Mehta M, Simoni SD, Reed L, Krystal J, Nutt DJ, Barker G. P.3.001 Ketamine-induced changes in anterior cingulate glutamate levels correlate with positive symptom generation European Neuropsychopharmacology. 22. DOI: 10.1016/S0924-977X(12)70054-8  1
2011 Gueorguieva R, Mallinckrodt C, Krystal JH. Trajectories of depression severity in clinical trials of duloxetine: insights into antidepressant and placebo responses. Archives of General Psychiatry. 68: 1227-37. PMID 22147842 DOI: 10.1001/Archgenpsychiatry.2011.132  1
2011 Zuo L, Zhang CK, Wang F, Li CS, Zhao H, Lu L, Zhang XY, Lu L, Zhang H, Zhang F, Krystal JH, Luo X. A novel, functional and replicable risk gene region for alcohol dependence identified by genome-wide association study. Plos One. 6: e26726. PMID 22096494 DOI: 10.1371/Journal.Pone.0026726  1
2011 Marder SR, Roth B, Sullivan PF, Scolnick EM, Nestler EJ, Geyer MA, Welnberger DR, Karayiorgou M, Guidotti A, Gingrich J, Akbarian S, Buchanan RW, Lieberman JA, Conn PJ, Haggarty SJ, ... ... Krystal JH, et al. Advancing drug discovery for schizophrenia. Annals of the New York Academy of Sciences. 1236: 30-43. PMID 22032400 DOI: 10.1111/J.1749-6632.2011.06216.X  1
2011 Murrough JW, Czermak C, Henry S, Nabulsi N, Gallezot JD, Gueorguieva R, Planeta-Wilson B, Krystal JH, Neumaier JF, Huang Y, Ding YS, Carson RE, Neumeister A. The effect of early trauma exposure on serotonin type 1B receptor expression revealed by reduced selective radioligand binding. Archives of General Psychiatry. 68: 892-900. PMID 21893657 DOI: 10.1001/Archgenpsychiatry.2011.91  1
2011 Murrough JW, Huang Y, Hu J, Henry S, Williams W, Gallezot JD, Bailey CR, Krystal JH, Carson RE, Neumeister A. Reduced amygdala serotonin transporter binding in posttraumatic stress disorder. Biological Psychiatry. 70: 1033-8. PMID 21855859 DOI: 10.1016/J.Biopsych.2011.07.003  1
2011 Krystal JH, Rosenheck RA, Cramer JA, Vessicchio JC, Jones KM, Vertrees JE, Horney RA, Huang GD, Stock C. Adjunctive risperidone treatment for antidepressant-resistant symptoms of chronic military service-related PTSD: a randomized trial. Jama. 306: 493-502. PMID 21813427 DOI: 10.1001/Jama.2011.1080  1
2011 Xie P, Kranzler HR, Krauthammer M, Cosgrove KP, Oslin D, Anton RF, Farrer LA, Picciotto MR, Krystal JH, Zhao H, Gelernter J. Rare nonsynonymous variants in alpha-4 nicotinic acetylcholine receptor gene protect against nicotine dependence. Biological Psychiatry. 70: 528-36. PMID 21683344 DOI: 10.1016/J.Biopsych.2011.04.017  1
2011 Carter CS, Barch DM, Bullmore E, Breiling J, Buchanan RW, Butler P, Cohen JD, Geyer M, Gollub R, Green MF, Jaeger J, Krystal JH, Moore H, Nuechterlein K, Robbins T, et al. Cognitive Neuroscience Treatment Research to Improve Cognition in Schizophrenia II: developing imaging biomarkers to enhance treatment development for schizophrenia and related disorders. Biological Psychiatry. 70: 7-12. PMID 21529781 DOI: 10.1016/J.Biopsych.2011.01.041  1
2011 Soyka M, Kranzler HR, van den Brink W, Krystal J, Möller HJ, Kasper S. The World Federation of Societies of Biological Psychiatry (WFSBP) guidelines for the biological treatment of substance use and related disorders. Part 2: Opioid dependence. The World Journal of Biological Psychiatry : the Official Journal of the World Federation of Societies of Biological Psychiatry. 12: 160-87. PMID 21486104 DOI: 10.3109/15622975.2011.561872  1
2011 Rosenheck RA, Krystal JH, Lew R, Barnett PG, Fiore L, Valley D, Thwin SS, Vertrees JE, Liang MH. Long-acting risperidone and oral antipsychotics in unstable schizophrenia. The New England Journal of Medicine. 364: 842-51. PMID 21366475 DOI: 10.1056/Nejmoa1005987  1
2011 Freeman WM, Vanguilder HD, Guidone E, Krystal JH, Grant KA, Vrana KE. Plasma proteomic alterations in non-human primates and humans after chronic alcohol self-administration. The International Journal of Neuropsychopharmacology / Official Scientific Journal of the Collegium Internationale Neuropsychopharmacologicum (Cinp). 14: 899-911. PMID 21303580 DOI: 10.1017/S1461145711000046  1
2011 Cosgrove KP, Esterlis I, Mason GF, Bois F, O'Malley SS, Krystal JH. Neuroimaging insights into the role of cortical GABA systems and the influence of nicotine on the recovery from alcohol dependence. Neuropharmacology. 60: 1318-25. PMID 21276806 DOI: 10.1016/J.Neuropharm.2011.01.020  1
2011 Rosenheck RA, Krystal JH, Lew R, Barnett PG, Thwin SS, Fiore L, Valley D, Huang GD, Neal C, Vertrees JE, Liang MH. Challenges in the design and conduct of controlled clinical effectiveness trials in schizophrenia. Clinical Trials (London, England). 8: 196-204. PMID 21270143 DOI: 10.1177/1740774510392931  1
2011 Valentine GW, Mason GF, Gomez R, Fasula M, Watzl J, Pittman B, Krystal JH, Sanacora G. The antidepressant effect of ketamine is not associated with changes in occipital amino acid neurotransmitter content as measured by [(1)H]-MRS. Psychiatry Research. 191: 122-7. PMID 21232924 DOI: 10.1016/J.Pscychresns.2010.10.009  1
2011 Gueorguieva R, Wu R, Donovan D, Rounsaville BJ, Couper D, Krystal JH, O'Malley SS. Baseline trajectories of drinking moderate acamprosate and naltrexone effects in the COMBINE study. Alcoholism, Clinical and Experimental Research. 35: 523-31. PMID 21143249 DOI: 10.1111/J.1530-0277.2010.01369.X  1
2011 Andrews MM, Meda SA, Thomas AD, Potenza MN, Krystal JH, Worhunsky P, Stevens MC, O'Malley S, Book GA, Reynolds B, Pearlson GD. Individuals family history positive for alcoholism show functional magnetic resonance imaging differences in reward sensitivity that are related to impulsivity factors. Biological Psychiatry. 69: 675-83. PMID 21126735 DOI: 10.1016/J.Biopsych.2010.09.049  1
2011 Krystal JH, Petrakis IL, Limoncelli D, Nappi SK, Trevisan L, Pittman B, D'Souza DC, Suckow RF. Characterization of the interactive effects of glycine and D-cycloserine in men: further evidence for enhanced NMDA receptor function associated with human alcohol dependence. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 36: 701-10. PMID 21124304 DOI: 10.1038/Npp.2010.203  1
2011 Hallak JE, Dursun SM, Bosi DC, de Macedo LR, Machado-de-Sousa JP, Abrão J, Crippa JA, McGuire P, Krystal JH, Baker GB, Zuardi AW. The interplay of cannabinoid and NMDA glutamate receptor systems in humans: preliminary evidence of interactive effects of cannabidiol and ketamine in healthy human subjects. Progress in Neuro-Psychopharmacology & Biological Psychiatry. 35: 198-202. PMID 21062637 DOI: 10.1016/J.Pnpbp.2010.11.002  1
2011 Corlett PR, Honey GD, Krystal JH, Fletcher PC. Glutamatergic model psychoses: prediction error, learning, and inference. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 36: 294-315. PMID 20861831 DOI: 10.1038/Npp.2010.163  1
2011 Narayanan B, Jiantonio R, Stevens M, Krystal JH, Pearlson G. Effects of memantine on resting state Electroencephalogram (EEG) and P300 Event-Related Potential (ERP) in subjects with and without family history of alcoholism F1000research. 2. DOI: 10.7490/F1000Research.1198.1  1
2011 Murrough JW, Czermak C, Henry S, Nabulsi N, Gallezot J, Gueorguieva R, Planeta-Wilson B, Krystal JH, Neumaier JF, Huang Y, Ding Y, Carson RE, Neumeister A. Age at first trauma is associated with serotonin 1B receptor reductions and comorbid depression in posttraumatic stress disorder F1000research. 2. DOI: 10.7490/F1000Research.1190.1  1
2011 Krystal JH. Biological psychiatry: A time of opportunity, a time of challenge Biological Psychiatry. 70: 3-4. DOI: 10.1016/J.Biopsych.2011.04.020  1
2011 Krystal JH, Moghaddam B. Contributions of Glutamate and GABA Systems to the Neurobiology and Treatment of Schizophrenia Schizophrenia: Third Edition. 433-461. DOI: 10.1002/9781444327298.ch21  1
2011 Rosenheck RA, Krystal JH. The authors reply New England Journal of Medicine. 364: 2265-2266.  1
2010 Krystal JH. N-methyl-D-aspartate glutamate receptor antagonists and the promise of rapid-acting antidepressants. Archives of General Psychiatry. 67: 1110-1. PMID 21041611 DOI: 10.1001/Archgenpsychiatry.2010.138  1
2010 Sewell RA, Perry EB, Karper LP, Bell MD, Lysaker P, Goulet JL, Brenner L, Erdos J, d'Souza DC, Seibyl JP, Krystal JH. Clinical significance of neurological soft signs in schizophrenia: factor analysis of the Neurological Evaluation Scale. Schizophrenia Research. 124: 1-12. PMID 20855185 DOI: 10.1016/J.Schres.2010.08.036  1
2010 Urban NB, Kegeles LS, Slifstein M, Xu X, Martinez D, Sakr E, Castillo F, Moadel T, O'Malley SS, Krystal JH, Abi-Dargham A. Sex differences in striatal dopamine release in young adults after oral alcohol challenge: a positron emission tomography imaging study with [¹¹C]raclopride. Biological Psychiatry. 68: 689-96. PMID 20678752 DOI: 10.1016/J.Biopsych.2010.06.005  1
2010 Krystal JH, Mathew SJ, D'Souza DC, Garakani A, Gunduz-Bruce H, Charney DS. Potential psychiatric applications of metabotropic glutamate receptor agonists and antagonists. Cns Drugs. 24: 669-93. PMID 20658799 DOI: 10.2165/11533230-000000000-00000  1
2010 Corlett PR, Taylor JR, Wang XJ, Fletcher PC, Krystal JH. Toward a neurobiology of delusions. Progress in Neurobiology. 92: 345-69. PMID 20558235 DOI: 10.1016/J.Pneurobio.2010.06.007  1
2010 Yun RJ, Krystal JH, Mathalon DH. Working memory overload: fronto-limbic interactions and effects on subsequent working memory function. Brain Imaging and Behavior. 4: 96-108. PMID 20503117 DOI: 10.1007/S11682-010-9089-9  1
2010 Corlett PR, D'Souza DC, Krystal JH. Capgras syndrome induced by ketamine in a healthy subject. Biological Psychiatry. 68: e1-2. PMID 20385373 DOI: 10.1016/J.Biopsych.2010.02.015  1
2010 Sen S, Kranzler HR, Krystal JH, Speller H, Chan G, Gelernter J, Guille C. A prospective cohort study investigating factors associated with depression during medical internship. Archives of General Psychiatry. 67: 557-65. PMID 20368500 DOI: 10.1001/Archgenpsychiatry.2010.41  1
2010 Cosgrove KP, Kloczynski T, Bois F, Pittman B, Tamagnan G, Seibyl JP, Krystal JH, Staley JK. Decreased Beta(2)*-nicotinic acetylcholine receptor availability after chronic ethanol exposure in nonhuman primates. Synapse (New York, N.Y.). 64: 729-32. PMID 20340174 DOI: 10.1002/Syn.20795  1
2010 Hu J, Henry S, Gallezot JD, Ropchan J, Neumaier JF, Potenza MN, Sinha R, Krystal JH, Huang Y, Ding YS, Carson RE, Neumeister A. Serotonin 1B receptor imaging in alcohol dependence. Biological Psychiatry. 67: 800-3. PMID 20172504 DOI: 10.1016/J.Biopsych.2009.12.028  1
2010 Aikins DE, Anticevic A, Kiehl KA, Krystal JH. Sex-related differences in amygdala activity influences immediate memory. Neuroreport. 21: 273-6. PMID 20093991 DOI: 10.1097/Wnr.0B013E328335B3F9  1
2010 Esterlis I, Cosgrove KP, Petrakis IL, McKee SA, Bois F, Krantzler E, Stiklus SM, Perry EB, Tamagnan GD, Seibyl JP, Krystal JH, Staley JK. SPECT imaging of nicotinic acetylcholine receptors in nonsmoking heavy alcohol drinking individuals. Drug and Alcohol Dependence. 108: 146-50. PMID 20074869 DOI: 10.1016/J.Drugalcdep.2009.12.006  1
2010 Gueorguieva R, Wu R, Donovan D, Rounsaville BJ, Couper D, Krystal JH, O'Malley SS. Naltrexone and combined behavioral intervention effects on trajectories of drinking in the COMBINE study. Drug and Alcohol Dependence. 107: 221-9. PMID 19969427 DOI: 10.1016/J.Drugalcdep.2009.10.017  1
2010 Otto MW, Tolin DF, Simon NM, Pearlson GD, Basden S, Meunier SA, Hofmann SG, Eisenmenger K, Krystal JH, Pollack MH. Efficacy of d-cycloserine for enhancing response to cognitive-behavior therapy for panic disorder. Biological Psychiatry. 67: 365-70. PMID 19811776 DOI: 10.1016/J.Biopsych.2009.07.036  1
2010 Landeros-Weisenberger A, Bloch MH, Kelmendi B, Wegner R, Nudel J, Dombrowski P, Pittenger C, Krystal JH, Goodman WK, Leckman JF, Coric V. Dimensional predictors of response to SRI pharmacotherapy in obsessive-compulsive disorder. Journal of Affective Disorders. 121: 175-9. PMID 19577308 DOI: 10.1016/J.Jad.2009.06.010  1
2010 Dickerson D, Pittman B, Ralevski E, Perrino A, Limoncelli D, Edgecombe J, Acampora G, Krystal JH, Petrakis I. Ethanol-like effects of thiopental and ketamine in healthy humans. Journal of Psychopharmacology (Oxford, England). 24: 203-11. PMID 19028835 DOI: 10.1177/0269881108098612  1
2010 Nakic M, Krystal JH, Bhagwagar Z. Neurotransmitter Systems in Bipolar Disorder Bipolar Disorder: Clinical and Neurobiological Foundations. 210-227. DOI: 10.1002/9780470661277.Ch16  1
2010 Sen S, Kranzler HR, Krystal JH, Speller H, Chan G, Gelernter J, Guille C. In reply Archives of General Psychiatry. 67: 568-569. DOI: 10.1001/archgenpsychiatry.2010.53  1
2010 Krystal JH, Tolin DF, Sanacora G, Castner SA, Williams GV, Aikins DE, Hoffman RE, D'Souza DC. Neuroplasticity as a target of the pharmacotherapy of anxiety disorders, mood disorders and schizophrenia | Neuroplastyczność jako cel dla farmakoterapii zaburzeń lȩkowych, zaburzeń nastroju i schizofrenii Wiadomosci Psychiatryczne. 13: 163-173.  1
2009 Krystal JH. The evolution of the psychiatry research journal. The Journal of Clinical Psychiatry. 70: 1601-2. PMID 20031103 DOI: 10.4088/Jcp.09Com05629Whi  1
2009 Corlett PR, Simons JS, Pigott JS, Gardner JM, Murray GK, Krystal JH, Fletcher PC. Illusions and delusions: relating experimentally-induced false memories to anomalous experiences and ideas. Frontiers in Behavioral Neuroscience. 3: 53. PMID 19956402 DOI: 10.3389/Neuro.08.053.2009  1
2009 Zuo L, Luo X, Kranzler HR, Lu L, Rosenheck RA, Cramer J, van Kammen DP, Erdos J, Charney DS, Krystal J, Gelernter J. Association study of DTNBP1 with schizophrenia in a US sample. Psychiatric Genetics. 19: 292-304. PMID 19862852 DOI: 10.1097/Ypg.0B013E32832A50Bc  1
2009 Corlett PR, Krystal JH, Taylor JR, Fletcher PC. Why do delusions persist? Frontiers in Human Neuroscience. 3: 12. PMID 19636384 DOI: 10.3389/Neuro.09.012.2009  1
2009 Krystal JH, Tolin DF, Sanacora G, Castner SA, Williams GV, Aikins DE, Hoffman RE, D'Souza DC. Neuroplasticity as a target for the pharmacotherapy of anxiety disorders, mood disorders, and schizophrenia. Drug Discovery Today. 14: 690-7. PMID 19460458 DOI: 10.1016/J.Drudis.2009.05.002  1
2009 Cosgrove KP, Krantzler E, Frohlich EB, Stiklus S, Pittman B, Tamagnan GD, Baldwin RM, Bois F, Seibyl JP, Krystal JH, O'Malley SS, Staley JK. Dopamine and serotonin transporter availability during acute alcohol withdrawal: effects of comorbid tobacco smoking. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 34: 2218-26. PMID 19440191 DOI: 10.1038/Npp.2009.49  1
2009 Zuo L, Luo X, Krystal JH, Cramer J, Charney DS, Gelernter J. The efficacies of clozapine and haloperidol in refractory schizophrenia are related to DTNBP1 variation. Pharmacogenetics and Genomics. 19: 437-46. PMID 19369910 DOI: 10.1097/Fpc.0B013E32832B9Cfc  1
2009 Krystal JH, Neumeister A. Noradrenergic and serotonergic mechanisms in the neurobiology of posttraumatic stress disorder and resilience. Brain Research. 1293: 13-23. PMID 19332037 DOI: 10.1016/J.Brainres.2009.03.044  1
2009 Zuo L, Luo X, Listman JB, Kranzler HR, Wang S, Anton RF, Blumberg HP, Stein MB, Pearlson GD, Covault J, Charney DS, van Kammen DP, Price LH, Lappalainen J, Cramer J, ... Krystal JH, et al. Population admixture modulates risk for alcohol dependence. Human Genetics. 125: 605-13. PMID 19306106 DOI: 10.1007/S00439-009-0647-4  1
2009 Ranganathan M, Braley G, Pittman B, Cooper T, Perry E, Krystal J, D'Souza DC. The effects of cannabinoids on serum cortisol and prolactin in humans. Psychopharmacology. 203: 737-44. PMID 19083209 DOI: 10.1007/S00213-008-1422-2  1
2009 Barch DM, Carter CS, Arnsten A, Buchanan RW, Cohen JD, Geyer M, Green MF, Krystal JH, Nuechterlein K, Robbins T, Silverstein S, Smith EE, Strauss M, Wykes T, Heinssen R. Selecting paradigms from cognitive neuroscience for translation into use in clinical trials: proceedings of the third CNTRICS meeting. Schizophrenia Bulletin. 35: 109-14. PMID 19023126 DOI: 10.1093/Schbul/Sbn163  1
2009 Weder N, Yang BZ, Douglas-Palumberi H, Massey J, Krystal JH, Gelernter J, Kaufman J. MAOA genotype, maltreatment, and aggressive behavior: the changing impact of genotype at varying levels of trauma. Biological Psychiatry. 65: 417-24. PMID 18996506 DOI: 10.1016/J.Biopsych.2008.09.013  1
2009 Martinez D, Slifstein M, Gil R, Hwang DR, Huang Y, Perez A, Frankle WG, Laruelle M, Krystal J, Abi-Dargham A. Positron emission tomography imaging of the serotonin transporter and 5-HT(1A) receptor in alcohol dependence. Biological Psychiatry. 65: 175-80. PMID 18962444 DOI: 10.1016/J.Biopsych.2008.08.034  1
2009 Watson TD, Petrakis IL, Edgecombe J, Perrino A, Krystal JH, Mathalon DH. Modulation of the cortical processing of novel and target stimuli by drugs affecting glutamate and GABA neurotransmission. The International Journal of Neuropsychopharmacology / Official Scientific Journal of the Collegium Internationale Neuropsychopharmacologicum (Cinp). 12: 357-70. PMID 18771605 DOI: 10.1017/S1461145708009334  1
2009 Krystal JH. Biological Psychiatry: Real Progress Biological Psychiatry. 65: 3-4. DOI: 10.1016/J.Biopsych.2008.08.026  1
2008 Krishnan-Sarin S, O'Malley S, Krystal JH. Treatment implications: using neuroscience to guide the development of new pharmacotherapies for alcoholism. Alcohol Research & Health : the Journal of the National Institute On Alcohol Abuse and Alcoholism. 31: 400-7. PMID 23584013  1
2008 Southwick S, Friedman M, Krystal J. Does psychoeducation help prevent post traumatic psychological stress disorder? In reply. Psychiatry. 71: 303-7. PMID 19152277 DOI: 10.1521/Psyc.2008.71.4.303  1
2008 Perepletchikova F, Krystal JH, Kaufman J. Practitioner review: adolescent alcohol use disorders: assessment and treatment issues. Journal of Child Psychology and Psychiatry, and Allied Disciplines. 49: 1131-54. PMID 19017028 DOI: 10.1111/J.1469-7610.2008.01934.X  1
2008 Driesen NR, Leung HC, Calhoun VD, Constable RT, Gueorguieva R, Hoffman R, Skudlarski P, Goldman-Rakic PS, Krystal JH. Impairment of working memory maintenance and response in schizophrenia: functional magnetic resonance imaging evidence. Biological Psychiatry. 64: 1026-34. PMID 18823880 DOI: 10.1016/J.Biopsych.2008.07.029  1
2008 Pittenger C, Coric V, Banasr M, Bloch M, Krystal JH, Sanacora G. Riluzole in the treatment of mood and anxiety disorders. Cns Drugs. 22: 761-86. PMID 18698875 DOI: 10.2165/00023210-200822090-00004  1
2008 Krystal JH. Capitalizing on extrasynaptic glutamate neurotransmission to treat antipsychotic-resistant symptoms in schizophrenia. Biological Psychiatry. 64: 358-60. PMID 18694665 DOI: 10.1016/J.Biopsych.2008.06.011  1
2008 Carter CS, Barch DM, Buchanan RW, Bullmore E, Krystal JH, Cohen J, Geyer M, Green M, Nuechterlein KH, Robbins T, Silverstein S, Smith EE, Strauss M, Wykes T, Heinssen R. Identifying cognitive mechanisms targeted for treatment development in schizophrenia: an overview of the first meeting of the Cognitive Neuroscience Treatment Research to Improve Cognition in Schizophrenia Initiative. Biological Psychiatry. 64: 4-10. PMID 18466880 DOI: 10.1016/J.Biopsych.2008.03.020  1
2008 Sanacora G, Zarate CA, Krystal JH, Manji HK. Targeting the glutamatergic system to develop novel, improved therapeutics for mood disorders. Nature Reviews. Drug Discovery. 7: 426-37. PMID 18425072 DOI: 10.1038/Nrd2462  1
2008 Cavus I, Pan JW, Hetherington HP, Abi-Saab W, Zaveri HP, Vives KP, Krystal JH, Spencer SS, Spencer DD. Decreased hippocampal volume on MRI is associated with increased extracellular glutamate in epilepsy patients. Epilepsia. 49: 1358-66. PMID 18410365 DOI: 10.1111/J.1528-1167.2008.01603.X  1
2008 Krystal JH, Carter CS, Geschwind D, Manji HK, March JS, Nestler EJ, Zubieta JK, Charney DS, Goldman D, Gur RE, Lieberman JA, Roy-Byrne P, Rubinow DR, Anderson SA, Barondes S, et al. It is time to take a stand for medical research and against terrorism targeting medical scientists. Biological Psychiatry. 63: 725-7. PMID 18371494 DOI: 10.1016/J.Biopsych.2008.03.005  1
2008 Norberg MM, Krystal JH, Tolin DF. A meta-analysis of D-cycloserine and the facilitation of fear extinction and exposure therapy. Biological Psychiatry. 63: 1118-26. PMID 18313643 DOI: 10.1016/J.Biopsych.2008.01.012  1
2008 Jackowski AP, Douglas-Palumberi H, Jackowski M, Win L, Schultz RT, Staib LW, Krystal JH, Kaufman J. Corpus callosum in maltreated children with posttraumatic stress disorder: a diffusion tensor imaging study. Psychiatry Research. 162: 256-61. PMID 18296031 DOI: 10.1016/J.Pscychresns.2007.08.006  1
2008 Czermak C, Staley JK, Kasserman S, Bois F, Young T, Henry S, Tamagnan GD, Seibyl JP, Krystal JH, Neumeister A. beta2 Nicotinic acetylcholine receptor availability in post-traumatic stress disorder. The International Journal of Neuropsychopharmacology / Official Scientific Journal of the Collegium Internationale Neuropsychopharmacologicum (Cinp). 11: 419-24. PMID 18190729 DOI: 10.1017/S1461145707008152  1
2008 D'Souza DC, Ranganathan M, Braley G, Gueorguieva R, Zimolo Z, Cooper T, Perry E, Krystal J. Blunted psychotomimetic and amnestic effects of delta-9-tetrahydrocannabinol in frequent users of cannabis. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 33: 2505-16. PMID 18185500 DOI: 10.1038/Sj.Npp.1301643  1
2008 Stone JM, Erlandsson K, Arstad E, Squassante L, Teneggi V, Bressan RA, Krystal JH, Ell PJ, Pilowsky LS. Relationship between ketamine-induced psychotic symptoms and NMDA receptor occupancy: a [(123)I]CNS-1261 SPET study. Psychopharmacology. 197: 401-8. PMID 18176855 DOI: 10.1007/S00213-007-1047-X  1
2008 Krystal JH, Gueorguieva R, Cramer J, Collins J, Rosenheck R. Naltrexone is associated with reduced drinking by alcohol dependent patients receiving antidepressants for mood and anxiety symptoms: results from VA Cooperative Study No. 425, "Naltrexone in the treatment of alcoholism". Alcoholism, Clinical and Experimental Research. 32: 85-91. PMID 18070245 DOI: 10.1111/J.1530-0277.2007.00555.X  1
2008 Trevisan L, Petrakis IL, Pittman B, Gueorguieva R, D'Souza DC, Perry E, Limoncelli D, Krystal JH. Absence of significant interactive effects of high-dose D-cycloserine and ethanol in healthy human subjects: preliminary insights into ethanol actions at the glycine B site of NMDA glutamate receptors. Alcoholism, Clinical and Experimental Research. 32: 36-42. PMID 18028532 DOI: 10.1111/J.1530-0277.2007.00543.X  1
2008 Esterlis I, Bois F, Cosgrove KP, Stiklus SM, Perry E, Tamagnan GD, Seibyl JP, Krystal JH, Staley JK. Sex differences in nicotinic acetylcholine receptor availability in heavy alcohol drinkers Neuroimage. 41. DOI: 10.1016/J.Neuroimage.2008.04.150  1
2008 Urban N, Martinez D, Zhou Y, Toda M, Xu X, Kegeles LS, Slifstein M, Pearlson G, Krystal J, Abi-Dargham A. New probes for imaging dopamine transmission in at risk subjects for alcoholism Neuroimage. 41. DOI: 10.1016/J.Neuroimage.2008.04.111  1
2007 Goff DC, Keefe R, Citrome L, Davy K, Krystal JH, Large C, Thompson TR, Volavka J, Webster EL. Lamotrigine as add-on therapy in schizophrenia: results of 2 placebo-controlled trials. Journal of Clinical Psychopharmacology. 27: 582-9. PMID 18004124 DOI: 10.1097/Jcp.0B013E31815Abf34  1
2007 Martinez D, Kim JH, Krystal J, Abi-Dargham A. Imaging the neurochemistry of alcohol and substance abuse. Neuroimaging Clinics of North America. 17: 539-55, x. PMID 17983969 DOI: 10.1016/J.Nic.2007.07.004  1
2007 Krystal JH. Neuroplasticity as a target for the pharmacotherapy of psychiatric disorders: new opportunities for synergy with psychotherapy. Biological Psychiatry. 62: 833-4. PMID 17916459 DOI: 10.1016/J.Biopsych.2007.08.017  1
2007 Ford JM, Krystal JH, Mathalon DH. Neural synchrony in schizophrenia: from networks to new treatments. Schizophrenia Bulletin. 33: 848-52. PMID 17567628 DOI: 10.1093/Schbul/Sbm062  1
2007 Krystal JH. Ketamine and the potential role for rapid-acting antidepressant medications. Swiss Medical Weekly. 137: 215-6. PMID 17525875  1
2007 McDougle CJ, Krystal JH. Pediatric psychopharmacology: mood, anxiety and disruptive behavior/pervasive developmental disorders. Psychopharmacology. 191: 1-3. PMID 17476481 DOI: 10.1007/S00213-007-0720-4  1
2007 Perry EB, Cramer JA, Cho HS, Petrakis IL, Karper LP, Genovese A, O'Donnell E, Krystal JH, D'Souza DC. Psychiatric safety of ketamine in psychopharmacology research. Psychopharmacology. 192: 253-60. PMID 17458544 DOI: 10.1007/S00213-007-0706-2  1
2007 Pittenger C, Sanacora G, Krystal JH. The NMDA receptor as a therapeutic target in major depressive disorder. Cns & Neurological Disorders Drug Targets. 6: 101-15. PMID 17430148 DOI: 10.2174/187152707780363267  1
2007 Pittman B, Gueorguieva R, Krupitsky E, Rudenko AA, Flannery BA, Krystal JH. Multidimensionality of the Alcohol Withdrawal Symptom Checklist: a factor analysis of the Alcohol Withdrawal Symptom Checklist and CIWA-Ar. Alcoholism, Clinical and Experimental Research. 31: 612-8. PMID 17374040 DOI: 10.1111/J.1530-0277.2007.00345.X  1
2007 Krupitsky EM, Rudenko AA, Burakov AM, Slavina TY, Grinenko AA, Pittman B, Gueorguieva R, Petrakis IL, Zvartau EE, Krystal JH. Antiglutamatergic strategies for ethanol detoxification: comparison with placebo and diazepam. Alcoholism, Clinical and Experimental Research. 31: 604-11. PMID 17374039 DOI: 10.1111/J.1530-0277.2007.00344.X  1
2007 Gelernter J, Gueorguieva R, Kranzler HR, Zhang H, Cramer J, Rosenheck R, Krystal JH. Opioid receptor gene (OPRM1, OPRK1, and OPRD1) variants and response to naltrexone treatment for alcohol dependence: results from the VA Cooperative Study. Alcoholism, Clinical and Experimental Research. 31: 555-63. PMID 17374034 DOI: 10.1111/J.1530-0277.2007.00339.X  1
2007 Krishnan-Sarin S, Krystal JH, Shi J, Pittman B, O'Malley SS. Family history of alcoholism influences naltrexone-induced reduction in alcohol drinking. Biological Psychiatry. 62: 694-7. PMID 17336941 DOI: 10.1016/J.Biopsych.2006.11.018  1
2007 Krupitsky EM, Neznanova O, Masalov D, Burakov AM, Didenko T, Romanova T, Tsoy M, Bespalov A, Slavina TY, Grinenko AA, Petrakis IL, Pittman B, Gueorguieva R, Zvartau EE, Krystal JH. Effect of memantine on cue-induced alcohol craving in recovering alcohol-dependent patients. The American Journal of Psychiatry. 164: 519-23. PMID 17329479 DOI: 10.1176/Ajp.2007.164.3.519  1
2007 Epperson CN, Pittman B, Czarkowski KA, Stiklus S, Krystal JH, Grillon C. Luteal-phase accentuation of acoustic startle response in women with premenstrual dysphoric disorder. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 32: 2190-8. PMID 17314917 DOI: 10.1038/Sj.Npp.1301351  1
2007 Hoffman RE, Hampson M, Wu K, Anderson AW, Gore JC, Buchanan RJ, Constable RT, Hawkins KA, Sahay N, Krystal JH. Probing the pathophysiology of auditory/verbal hallucinations by combining functional magnetic resonance imaging and transcranial magnetic stimulation. Cerebral Cortex (New York, N.Y. : 1991). 17: 2733-43. PMID 17298962 DOI: 10.1093/Cercor/Bhl183  1
2007 Gueorguieva R, Wu R, Pittman B, Cramer J, Rosenheck RA, O'malley SS, Krystal JH. New insights into the efficacy of naltrexone based on trajectory-based reanalyses of two negative clinical trials. Biological Psychiatry. 61: 1290-5. PMID 17224132 DOI: 10.1016/J.Biopsych.2006.09.038  1
2007 Sanacora G, Kendell SF, Levin Y, Simen AA, Fenton LR, Coric V, Krystal JH. Preliminary evidence of riluzole efficacy in antidepressant-treated patients with residual depressive symptoms. Biological Psychiatry. 61: 822-5. PMID 17141740 DOI: 10.1016/J.Biopsych.2006.08.037  1
2007 Kaufman J, Yang BZ, Douglas-Palumberi H, Crouse-Artus M, Lipschitz D, Krystal JH, Gelernter J. Genetic and environmental predictors of early alcohol use. Biological Psychiatry. 61: 1228-34. PMID 17123474 DOI: 10.1016/J.Biopsych.2006.06.039  1
2007 Lappalainen J, Krupitsky E, Kranzler HR, Luo X, Remizov M, Pchelina S, Taraskina A, Zvartau E, Räsanen P, Makikyro T, Somberg LK, Krystal JH, Stein MB, Gelernter J. Mutation screen of the GAD2 gene and association study of alcoholism in three populations. American Journal of Medical Genetics. Part B, Neuropsychiatric Genetics : the Official Publication of the International Society of Psychiatric Genetics. 144: 183-92. PMID 17034009 DOI: 10.1002/Ajmg.B.30377  1
2007 Epperson CN, Amin Z, Naftolin F, Cappiello A, Czarkowski KA, Stiklus S, Anderson GM, Krystal JH. The resistance to depressive relapse in menopausal women undergoing tryptophan depletion: preliminary findings. Journal of Psychopharmacology (Oxford, England). 21: 414-20. PMID 16891341 DOI: 10.1177/0269881106067330  1
2007 Krystal JH. Biological Psychiatry: Increasing Impact Biological Psychiatry. 62: 1203-1204. DOI: 10.1016/J.Biopsych.2007.09.021  1
2007 Heninger GR, Krystal JH, Duman RS, Bunney BS, Bowers MB, Aghajanian GK. The Neuroscience Research Program at the Connecticut Mental Health Center 40 Years of Academic Public Psychiatry. 77-95. DOI: 10.1002/9780470994580.ch4  1
2006 Krystal JH, D'Souza DC, Gallinat J, Driesen N, Abi-Dargham A, Petrakis I, Heinz A, Pearlson G. The vulnerability to alcohol and substance abuse in individuals diagnosed with schizophrenia. Neurotoxicity Research. 10: 235-52. PMID 17197373 DOI: 10.1007/Bf03033360  1
2006 Sasso DA, Kalanithi PS, Trueblood KV, Pittenger C, Kelmendi B, Wayslink S, Malison RT, Krystal JH, Coric V. Beneficial effects of the glutamate-modulating agent riluzole on disordered eating and pathological skin-picking behaviors. Journal of Clinical Psychopharmacology. 26: 685-7. PMID 17110840 DOI: 10.1097/01.Jcp.0000245567.29531.D6  1
2006 Neumeister A, Carson R, Henry S, Planeta-Wilson B, Binneman B, Maguire RP, Luckenbaugh DA, D'Souza C, Krystal JH, Frost JJ. Cerebral metabolic effects of intravenous glycine in healthy human subjects. Journal of Clinical Psychopharmacology. 26: 595-9. PMID 17110816 DOI: 10.1097/01.Jcp.0000245558.14284.Aa  1
2006 Krystal JH. Biological psychiatry: A new leadership team. Biological Psychiatry. 60: 794-5. PMID 17045860 DOI: 10.1016/J.Biopsych.2006.09.004  1
2006 Mason GF, Krystal JH. MR spectroscopy: its potential role for drug development for the treatment of psychiatric diseases. Nmr in Biomedicine. 19: 690-701. PMID 16986118 DOI: 10.1002/Nbm.1080  1
2006 D'Souza DC, Gil RB, Madonick S, Perry EB, Forselius-Bielen K, Braley G, Donahue L, Tellioglu T, Zimolo Z, Gueorguieva R, Krystal JH. Enhanced sensitivity to the euphoric effects of alcohol in schizophrenia. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 31: 2767-75. PMID 16985503 DOI: 10.1038/Sj.Npp.1301207  1
2006 Krystal JH, Staley J, Mason G, Petrakis IL, Kaufman J, Harris RA, Gelernter J, Lappalainen J. Gamma-aminobutyric acid type A receptors and alcoholism: intoxication, dependence, vulnerability, and treatment. Archives of General Psychiatry. 63: 957-68. PMID 16952998 DOI: 10.1001/Archpsyc.63.9.957  1
2006 Rasmusson AM, Pinna G, Paliwal P, Weisman D, Gottschalk C, Charney D, Krystal J, Guidotti A. Decreased cerebrospinal fluid allopregnanolone levels in women with posttraumatic stress disorder. Biological Psychiatry. 60: 704-13. PMID 16934764 DOI: 10.1016/J.Biopsych.2006.03.026  1
2006 Morgan CJ, Perry EB, Cho HS, Krystal JH, D'Souza DC. Greater vulnerability to the amnestic effects of ketamine in males. Psychopharmacology. 187: 405-14. PMID 16896964 DOI: 10.1007/S00213-006-0409-0  1
2006 Amin Z, Mason GF, Cavus I, Krystal JH, Rothman DL, Epperson CN. The interaction of neuroactive steroids and GABA in the development of neuropsychiatric disorders in women. Pharmacology, Biochemistry, and Behavior. 84: 635-43. PMID 16860856 DOI: 10.1016/J.Pbb.2006.06.007  1
2006 Epperson CN, Gueorguieva R, Czarkowski KA, Stiklus S, Sellers E, Krystal JH, Rothman DL, Mason GF. Preliminary evidence of reduced occipital GABA concentrations in puerperal women: a 1H-MRS study. Psychopharmacology. 186: 425-33. PMID 16724188 DOI: 10.1007/S00213-006-0313-7  1
2006 Pittenger C, Naungayan C, Kendell SF, Coric V, Malison R, Krystal JH, Sanacora GS. Visual hallucinations from the addition of riluzole to memantine and bupropion. Journal of Clinical Psychopharmacology. 26: 218-20. PMID 16633160 DOI: 10.1097/01.Jcp.0000203228.64117.9F  1
2006 Epperson CN, deWit H, Krystal JH. Advances in the translational neuroscience of neurosteroids. Psychopharmacology. 186: 265-6. PMID 16555064 DOI: 10.1007/S00213-006-0310-X  1
2006 Pittenger C, Krystal JH, Coric V. Glutamate-modulating drugs as novel pharmacotherapeutic agents in the treatment of obsessive-compulsive disorder. Neurorx : the Journal of the American Society For Experimental Neurotherapeutics. 3: 69-81. PMID 16490414 DOI: 10.1016/J.Nurx.2005.12.006  1
2006 Kaufman J, Yang BZ, Douglas-Palumberi H, Grasso D, Lipschitz D, Houshyar S, Krystal JH, Gelernter J. Brain-derived neurotrophic factor-5-HTTLPR gene interactions and environmental modifiers of depression in children. Biological Psychiatry. 59: 673-80. PMID 16458264 DOI: 10.1016/J.Biopsych.2005.10.026  1
2006 Blumberg HP, Krystal JH, Bansal R, Martin A, Dziura J, Durkin K, Martin L, Gerard E, Charney DS, Peterson BS. Age, rapid-cycling, and pharmacotherapy effects on ventral prefrontal cortex in bipolar disorder: a cross-sectional study. Biological Psychiatry. 59: 611-8. PMID 16414030 DOI: 10.1016/J.Biopsych.2005.08.031  1
2006 Krystal JH, Madonick S, Perry E, Gueorguieva R, Brush L, Wray Y, Belger A, D'Souza DC. Potentiation of low dose ketamine effects by naltrexone: potential implications for the pharmacotherapy of alcoholism. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 31: 1793-800. PMID 16395307 DOI: 10.1038/Sj.Npp.1300994  1
2006 Lafleur DL, Pittenger C, Kelmendi B, Gardner T, Wasylink S, Malison RT, Sanacora G, Krystal JH, Coric V. N-acetylcysteine augmentation in serotonin reuptake inhibitor refractory obsessive-compulsive disorder. Psychopharmacology. 184: 254-6. PMID 16374600 DOI: 10.1007/S00213-005-0246-6  1
2006 Mason GF, Petrakis IL, de Graaf RA, Gueorguieva R, Guidone E, Coric V, Epperson CN, Rothman DL, Krystal JH. Cortical gamma-aminobutyric acid levels and the recovery from ethanol dependence: preliminary evidence of modification by cigarette smoking. Biological Psychiatry. 59: 85-93. PMID 16289397 DOI: 10.1016/J.Biopsych.2005.06.009  1
2006 Pilowsky LS, Bressan RA, Stone JM, Erlandsson K, Mulligan RS, Krystal JH, Ell PJ. First in vivo evidence of an NMDA receptor deficit in medication-free schizophrenic patients. Molecular Psychiatry. 11: 118-9. PMID 16189506 DOI: 10.1038/Sj.Mp.4001751  1
2006 D'Souza DC, Gil RB, Zuzarte E, MacDougall LM, Donahue L, Ebersole JS, Boutros NN, Cooper T, Seibyl J, Krystal JH. gamma-Aminobutyric acid-serotonin interactions in healthy men: implications for network models of psychosis and dissociation. Biological Psychiatry. 59: 128-37. PMID 16140281 DOI: 10.1016/J.Biopsych.2005.06.020  1
2006 Sanacora G, Fenton LR, Fasula MK, Rothman DL, Levin Y, Krystal JH, Mason GF. Cortical gamma-aminobutyric acid concentrations in depressed patients receiving cognitive behavioral therapy. Biological Psychiatry. 59: 284-6. PMID 16139814 DOI: 10.1016/J.Biopsych.2005.07.015  1
2006 Staley J, Tellioglu T, Bois F, Palazzo C, McGuire-Schwartz N, Cosgrove K, Dyck Cv, Tamagnan G, Seibyl J, Krystal J, D'Souza D. [I-123] 5-IA-85380 SPECT imaging of beta2-nicotinic acetylcholine receptors in recently abstinent mentally healthy and schizophrenic smokers Neuroimage. 31. DOI: 10.1016/J.Neuroimage.2006.04.137  1
2006 D'Souza DC, Krystal JH. Glutamatergic function in the pathophysiology and treatment of psychiatric disorders Primary Psychiatry. 13: 36-37.  1
2006 Pittenger C, Bloch M, Wegner R, Teitelbaum C, Krystal JH, Coric V. Glutamatergic dysfunction in obsessive-compulsive disorder and the potential clinical utility of glutamate-modulating agents Primary Psychiatry. 13: 65-77.  1
2005 Pittenger C, Kelmendi B, Bloch M, Krystal JH, Coric V. Clinical treatment of obsessive compulsive disorder. Psychiatry (Edgmont (Pa. : Township)). 2: 34-43. PMID 21120095  1
2005 Pittenger C, Krystal JH, Coric V. Initial evidence of the beneficial effects of glutamate-modulating agents in the treatment of self-injurious behavior associated with borderline personality disorder. The Journal of Clinical Psychiatry. 66: 1492-3. PMID 16420092 DOI: 10.4088/Jcp.V66N1121D  1
2005 Keller MB, Krystal JH, Hen R, Neumeister A, Simon NM. Untangling depression and anxiety: clinical challenges. The Journal of Clinical Psychiatry. 66: 1477-84. PMID 16420087  1
2005 Blumberg HP, Fredericks C, Wang F, Kalmar JH, Spencer L, Papademetris X, Pittman B, Martin A, Peterson BS, Fulbright RK, Krystal JH. Preliminary evidence for persistent abnormalities in amygdala volumes in adolescents and young adults with bipolar disorder. Bipolar Disorders. 7: 570-6. PMID 16403182 DOI: 10.1111/J.1399-5618.2005.00264.X  1
2005 Blumberg HP, Donegan NH, Sanislow CA, Collins S, Lacadie C, Skudlarski P, Gueorguieva R, Fulbright RK, McGlashan TH, Gore JC, Krystal JH. Preliminary evidence for medication effects on functional abnormalities in the amygdala and anterior cingulate in bipolar disorder. Psychopharmacology. 183: 308-13. PMID 16249909 DOI: 10.1007/S00213-005-0156-7  1
2005 Cho RY, Ford JM, Krystal JH, Laruelle M, Cuthbert B, Carter CS. Functional neuroimaging and electrophysiology biomarkers for clinical trials for cognition in schizophrenia. Schizophrenia Bulletin. 31: 865-9. PMID 16166611 DOI: 10.1093/Schbul/Sbi050  1
2005 Li CS, Krystal JH, Mathalon DH. Fore-period effect and stop-signal reaction time. Experimental Brain Research. 167: 305-9. PMID 16160823 DOI: 10.1007/S00221-005-0110-2  1
2005 Krystal JH, Perry EB, Gueorguieva R, Belger A, Madonick SH, Abi-Dargham A, Cooper TB, Macdougall L, Abi-Saab W, D'Souza DC. Comparative and interactive human psychopharmacologic effects of ketamine and amphetamine: implications for glutamatergic and dopaminergic model psychoses and cognitive function. Archives of General Psychiatry. 62: 985-94. PMID 16143730 DOI: 10.1001/Archpsyc.62.9.985  1
2005 Staley JK, Gottschalk C, Petrakis IL, Gueorguieva R, O'Malley S, Baldwin R, Jatlow P, Verhoeff NP, Perry E, Weinzimmer D, Frohlich E, Ruff E, van Dyck CH, Seibyl JP, Innis RB, ... Krystal JH, et al. Cortical gamma-aminobutyric acid type A-benzodiazepine receptors in recovery from alcohol dependence: relationship to features of alcohol dependence and cigarette smoking. Archives of General Psychiatry. 62: 877-88. PMID 16061765 DOI: 10.1001/Archpsyc.62.8.877  1
2005 Martinez D, Gil R, Slifstein M, Hwang DR, Huang Y, Perez A, Kegeles L, Talbot P, Evans S, Krystal J, Laruelle M, Abi-Dargham A. Alcohol dependence is associated with blunted dopamine transmission in the ventral striatum. Biological Psychiatry. 58: 779-86. PMID 16018986 DOI: 10.1016/J.Biopsych.2005.04.044  1
2005 Coric V, Taskiran S, Pittenger C, Wasylink S, Mathalon DH, Valentine G, Saksa J, Wu YT, Gueorguieva R, Sanacora G, Malison RT, Krystal JH. Riluzole augmentation in treatment-resistant obsessive-compulsive disorder: an open-label trial. Biological Psychiatry. 58: 424-8. PMID 15993857 DOI: 10.1016/J.Biopsych.2005.04.043  1
2005 Bressan RA, Erlandsson K, Stone JM, Mulligan RS, Krystal JH, Ell PJ, Pilowsky LS. Impact of schizophrenia and chronic antipsychotic treatment on [123I]CNS-1261 binding to N-methyl-D-aspartate receptors in vivo. Biological Psychiatry. 58: 41-6. PMID 15992521 DOI: 10.1016/J.Biopsych.2005.03.016  1
2005 Hoffman RE, Gueorguieva R, Hawkins KA, Varanko M, Boutros NN, Wu YT, Carroll K, Krystal JH. Temporoparietal transcranial magnetic stimulation for auditory hallucinations: safety, efficacy and moderators in a fifty patient sample. Biological Psychiatry. 58: 97-104. PMID 15936729 DOI: 10.1016/J.Biopsych.2005.03.041  1
2005 Daurignac E, Toga AW, Jones DK, Aronen HJ, Hommer DW, Jernigan TL, Krystal JH, Mathalon DH. Applications of morphometric and diffusion tensor magnetic resonance imaging to the study of brain abnormalities in the alcoholism spectrum Alcoholism: Clinical and Experimental Research. 29: 159-166. PMID 15895490 DOI: 10.1097/01.Alc.0000150891.72900.62  1
2005 Mason GF, Bendszus M, Meyerhoff DJ, Hetherington HP, Schweinsburg B, Ross BD, Taylor MJ, Krystal JH. Magnetic resonance spectroscopic studies of alcoholism: From heavy drinking to alcohol dependence and back again Alcoholism: Clinical and Experimental Research. 29: 150-158. PMID 15895489 DOI: 10.1097/01.Alc.0000150010.72739.58  1
2005 Kiehl KA, Stevens MC, Celone K, Kurtz M, Krystal JH. Abnormal hemodynamics in schizophrenia during an auditory oddball task. Biological Psychiatry. 57: 1029-40. PMID 15860344 DOI: 10.1016/J.Biopsych.2005.01.035  1
2005 Lappalainen J, Krupitsky E, Remizov M, Pchelina S, Taraskina A, Zvartau E, Somberg LK, Covault J, Kranzler HR, Krystal JH, Gelernter J. Association between alcoholism and gamma-amino butyric acid alpha2 receptor subtype in a Russian population. Alcoholism, Clinical and Experimental Research. 29: 493-8. PMID 15834213 DOI: 10.1097/01.Alc.0000158938.97464.90  1
2005 D'Souza DC, Abi-Saab WM, Madonick S, Forselius-Bielen K, Doersch A, Braley G, Gueorguieva R, Cooper TB, Krystal JH. Delta-9-tetrahydrocannabinol effects in schizophrenia: implications for cognition, psychosis, and addiction. Biological Psychiatry. 57: 594-608. PMID 15780846 DOI: 10.1016/J.Biopsych.2004.12.006  1
2005 Kendell SF, Krystal JH, Sanacora G. GABA and glutamate systems as therapeutic targets in depression and mood disorders. Expert Opinion On Therapeutic Targets. 9: 153-68. PMID 15757488 DOI: 10.1517/14728222.9.1.153  1
2005 Cho HS, D'Souza DC, Gueorguieva R, Perry EB, Madonick S, Karper LP, Abi-Dargham A, Belger A, Abi-Saab W, Lipschitz D, Bennet A, Seibyl JP, Krystal JH. Absence of behavioral sensitization in healthy human subjects following repeated exposure to ketamine. Psychopharmacology. 179: 136-43. PMID 15682309 DOI: 10.1007/S00213-004-2066-5  1
2005 Cavus I, Kasoff WS, Cassaday MP, Jacob R, Gueorguieva R, Sherwin RS, Krystal JH, Spencer DD, Abi-Saab WM. Extracellular metabolites in the cortex and hippocampus of epileptic patients. Annals of Neurology. 57: 226-35. PMID 15668975 DOI: 10.1002/Ana.20380  1
2005 Jacobsen LK, Krystal JH, Mencl WE, Westerveld M, Frost SJ, Pugh KR. Effects of smoking and smoking abstinence on cognition in adolescent tobacco smokers. Biological Psychiatry. 57: 56-66. PMID 15607301 DOI: 10.1016/J.Biopsych.2004.10.022  1
2005 Epperson CN, O'Malley S, Czarkowski KA, Gueorguieva R, Jatlow P, Sanacora G, Rothman DL, Krystal JH, Mason GF. Sex, GABA, and nicotine: the impact of smoking on cortical GABA levels across the menstrual cycle as measured with proton magnetic resonance spectroscopy. Biological Psychiatry. 57: 44-8. PMID 15607299 DOI: 10.1016/J.Biopsych.2004.09.021  1
2005 Krystal JH, Abi-Saab W, Perry E, D'Souza DC, Liu N, Gueorguieva R, McDougall L, Hunsberger T, Belger A, Levine L, Breier A. Preliminary evidence of attenuation of the disruptive effects of the NMDA glutamate receptor antagonist, ketamine, on working memory by pretreatment with the group II metabotropic glutamate receptor agonist, LY354740, in healthy human subjects. Psychopharmacology. 179: 303-9. PMID 15309376 DOI: 10.1007/S00213-004-1982-8  1
2005 Tsoy M, Krupitsky EM, Neznanova ON, Burakov AM, Didenko TY, Masalov DV, Romanova TN, Bespalov AY, Zvartau EE, Krystal J. P.3.10 Ethanol-like effects of N-methyl-d-aspartatereceptors antagonist memantine, and its ability to prevent cue induced alcohol craving European Neuropsychopharmacology. 15. DOI: 10.1016/S0924-977X(05)80177-4  1
2004 Krystal JH, Duman R. What's missing in posttraumatic stress disorder research? Studies of human postmortem tissue. Psychiatry. 67: 398-403. PMID 15801380 DOI: 10.1521/Psyc.67.4.398.56567  1
2004 Goddard AW, Mason GF, Appel M, Rothman DL, Gueorguieva R, Behar KL, Krystal JH. Impaired GABA neuronal response to acute benzodiazepine administration in panic disorder. The American Journal of Psychiatry. 161: 2186-93. PMID 15569888 DOI: 10.1176/Appi.Ajp.161.12.2186  1
2004 Kaufman J, Yang BZ, Douglas-Palumberi H, Houshyar S, Lipschitz D, Krystal JH, Gelernter J. Social supports and serotonin transporter gene moderate depression in maltreated children. Proceedings of the National Academy of Sciences of the United States of America. 101: 17316-21. PMID 15563601 DOI: 10.1073/Pnas.0404376101  1
2004 Sanacora G, Kendell SF, Fenton L, Coric V, Krystal JH. Riluzole augmentation for treatment-resistant depression. The American Journal of Psychiatry. 161: 2132. PMID 15514421 DOI: 10.1176/Appi.Ajp.161.11.2132  1
2004 Petrakis IL, Limoncelli D, Gueorguieva R, Jatlow P, Boutros NN, Trevisan L, Gelernter J, Krystal JH. Altered NMDA glutamate receptor antagonist response in individuals with a family vulnerability to alcoholism. The American Journal of Psychiatry. 161: 1776-82. PMID 15465973 DOI: 10.1176/Ajp.161.10.1776  1
2004 Blumberg HP, Kaufman J, Martin A, Charney DS, Krystal JH, Peterson BS. Significance of adolescent neurodevelopment for the neural circuitry of bipolar disorder. Annals of the New York Academy of Sciences. 1021: 376-83. PMID 15251913 DOI: 10.1196/Annals.1308.048  1
2004 Sanacora G, Gueorguieva R, Epperson CN, Wu YT, Appel M, Rothman DL, Krystal JH, Mason GF. Subtype-specific alterations of gamma-aminobutyric acid and glutamate in patients with major depression. Archives of General Psychiatry. 61: 705-13. PMID 15237082 DOI: 10.1001/Archpsyc.61.7.705  1
2004 D'Souza DC, Perry E, MacDougall L, Ammerman Y, Cooper T, Wu YT, Braley G, Gueorguieva R, Krystal JH. The psychotomimetic effects of intravenous delta-9-tetrahydrocannabinol in healthy individuals: implications for psychosis. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 29: 1558-72. PMID 15173844 DOI: 10.1038/Sj.Npp.1300496  1
2004 Lappalainen J, Kranzler HR, Petrakis I, Somberg LK, Page G, Krystal JH, Gelernter J. Confirmation and fine mapping of the chromosome 1 alcohol dependence risk locus. Molecular Psychiatry. 9: 312-9. PMID 15094791 DOI: 10.1038/Sj.Mp.4001429  1
2004 Jacobsen LK, D'Souza DC, Mencl WE, Pugh KR, Skudlarski P, Krystal JH. Nicotine effects on brain function and functional connectivity in schizophrenia. Biological Psychiatry. 55: 850-8. PMID 15050867 DOI: 10.1016/J.Biopsych.2003.12.023  1
2004 Gueorguieva R, Krystal JH. Move over ANOVA: progress in analyzing repeated-measures data and its reflection in papers published in the Archives of General Psychiatry. Archives of General Psychiatry. 61: 310-7. PMID 14993119 DOI: 10.1001/Archpsyc.61.3.310  1
2004 Goddard AW, Mason GF, Rothman DL, Behar KL, Petroff OA, Krystal JH. Family psychopathology and magnitude of reductions in occipital cortex GABA levels in panic disorder. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 29: 639-40. PMID 14973435 DOI: 10.1038/Sj.Npp.1300374  1
2004 Lappalainen J, Sanacora G, Kranzler HR, Malison R, Hibbard ES, Price LH, Krystal J, Gelernter J. Mutation screen of the glutamate decarboxylase-67 gene and haplotype association to unipolar depression. American Journal of Medical Genetics. Part B, Neuropsychiatric Genetics : the Official Publication of the International Society of Psychiatric Genetics. 124: 81-6. PMID 14681921 DOI: 10.1002/Ajmg.B.20055  1
2004 Jacobsen LK, Mencl WE, Pugh KR, Skudlarski P, Krystal JH. Preliminary evidence of hippocampal dysfunction in adolescent MDMA ("ecstasy") users: possible relationship to neurotoxic effects. Psychopharmacology. 173: 383-90. PMID 14647960 DOI: 10.1007/S00213-003-1679-4  1
2004 Petrakis IL, O'Malley S, Rounsaville B, Poling J, McHugh-Strong C, Krystal JH. Naltrexone augmentation of neuroleptic treatment in alcohol abusing patients with schizophrenia. Psychopharmacology. 172: 291-7. PMID 14634716 DOI: 10.1007/S00213-003-1658-9  1
2004 Perry EB, Gil R, Miles D, Brenner L, MacDougall L, Johnson R, Degen K, Gueorguieva R, Petrakis IL, Krystal JH, D'Souza DC. Mazindol augmentation of antipsychotic treatment for schizophrenic patients with comorbid cocaine abuse or dependence: A preliminary double-blind, randomized, placebo-controlled trial Journal of Dual Diagnosis. 1: 37-47. DOI: 10.1300/J374v01n01_04  1
2004 Krishnan-Sarin S, Shih J, Krystal J, Malley SO. Hpa Axis Responsivity And Alcohol Drinking: Interactive Effects Of Family History Of Alcoholism And Naltrexone Treatment. Alcoholism: Clinical and Experimental Research. 28. DOI: 10.1097/00000374-200408002-00397  1
2003 Kane JM, Krystal J, Correll CU. Treatment Models and Designs for Intervention Research During the Psychotic Prodrome Schizophrenia Bulletin. 29: 747-756. PMID 14989412 DOI: 10.1093/Oxfordjournals.Schbul.A007044  0.01
2003 Sanacora G, Rothman DL, Mason G, Krystal JH. Clinical studies implementing glutamate neurotransmission in mood disorders. Annals of the New York Academy of Sciences. 1003: 292-308. PMID 14684453 DOI: 10.1196/Annals.1300.018  1
2003 Krystal JH, Petrakis IL, Krupitsky E, Schutz C, Trevisan L, D'Souza DC. NMDA receptor antagonism and the ethanol intoxication signal: from alcoholism risk to pharmacotherapy. Annals of the New York Academy of Sciences. 1003: 176-84. PMID 14684445 DOI: 10.1196/Annals.1300.010  1
2003 Heinz A, Schäfer M, Higley JD, Krystal JH, Goldman D. Neurobiological correlates of the disposition and maintenance of alcoholism. Pharmacopsychiatry. 36: S255-8. PMID 14677088 DOI: 10.1055/s-2003-45139  1
2003 Blumberg HP, Kaufman J, Martin A, Whiteman R, Zhang JH, Gore JC, Charney DS, Krystal JH, Peterson BS. Amygdala and hippocampal volumes in adolescents and adults with bipolar disorder. Archives of General Psychiatry. 60: 1201-8. PMID 14662552 DOI: 10.1001/Archpsyc.60.12.1201  1
2003 Cramer JA, Rosenheck R, Kirk G, Krol W, Krystal J. Medication compliance feedback and monitoring in a clinical trial: Predictors and outcomes Value in Health. 6: 566-573. PMID 14627063 DOI: 10.1046/J.1524-4733.2003.65269.X  1
2003 Roberts LW, Krystal J. A time of promise, a time of promises: ethical issues in advancing psychopharmacological research. Psychopharmacology. 171: 1-5. PMID 14615879 DOI: 10.1007/S00213-003-1704-7  0.01
2003 Harvey PD, Geyer MA, Robbins TW, Krystal JH. Cognition in schizophrenia: from basic science to clinical treatment. Psychopharmacology. 169: 213-4. PMID 12955286 DOI: 10.1007/S00213-003-1581-0  0.01
2003 Krystal JH, D'Souza DC, Mathalon D, Perry E, Belger A, Hoffman R. NMDA receptor antagonist effects, cortical glutamatergic function, and schizophrenia: toward a paradigm shift in medication development. Psychopharmacology. 169: 215-33. PMID 12955285 DOI: 10.1007/S00213-003-1582-Z  1
2003 Mathalon DH, Rapoport JL, Davis KL, Krystal JH. Neurotoxicity, neuroplasticity, and magnetic resonance imaging morphometry. Archives of General Psychiatry. 60: 846-8; author reply . PMID 12912768 DOI: 10.1001/Archpsyc.60.8.846  1
2003 Krystal JH, Petrakis IL, Limoncelli D, Webb E, Gueorgueva R, D'Souza DC, Boutros NN, Trevisan L, Charney DS. Altered NMDA glutamate receptor antagonist response in recovering ethanol-dependent patients. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 28: 2020-8. PMID 12888778 DOI: 10.1038/Sj.Npp.1300252  1
2003 Blumberg HP, Martin A, Kaufman J, Leung HC, Skudlarski P, Lacadie C, Fulbright RK, Gore JC, Charney DS, Krystal JH, Peterson BS. Frontostriatal abnormalities in adolescents with bipolar disorder: preliminary observations from functional MRI. The American Journal of Psychiatry. 160: 1345-7. PMID 12832254 DOI: 10.1176/Appi.Ajp.160.7.1345  1
2003 Krystal JH, Petrakis IL, Mason G, Trevisan L, D'Souza DC. N-methyl-D-aspartate glutamate receptors and alcoholism: reward, dependence, treatment, and vulnerability. Pharmacology & Therapeutics. 99: 79-94. PMID 12804700 DOI: 10.1016/S0163-7258(03)00054-8  1
2003 Blumberg HP, Leung HC, Skudlarski P, Lacadie CM, Fredericks CA, Harris BC, Charney DS, Gore JC, Krystal JH, Peterson BS. A functional magnetic resonance imaging study of bipolar disorder: state- and trait-related dysfunction in ventral prefrontal cortices. Archives of General Psychiatry. 60: 601-9. PMID 12796223 DOI: 10.1001/Archpsyc.60.6.601  1
2003 Morgan CA, Krystal JH, Southwick SM. Toward early pharmacological posttraumatic stress intervention. Biological Psychiatry. 53: 834-43. PMID 12725976 DOI: 10.1016/S0006-3223(03)00116-1  1
2003 Sierra M, Phillips ML, Ivin G, Krystal J, David AS. A placebo-controlled, cross-over trial of lamotrigine in depersonalization disorder. Journal of Psychopharmacology (Oxford, England). 17: 103-5. PMID 12680746 DOI: 10.1177/0269881103017001712  1
2003 Coric V, Milanovic S, Wasylink S, Patel P, Malison R, Krystal JH. Beneficial effects of the antiglutamatergic agent riluzole in a patient diagnosed with obsessive-compulsive disorder and major depressive disorder. Psychopharmacology. 167: 219-20. PMID 12658528 DOI: 10.1007/S00213-003-1396-Z  1
2003 Sanacora G, Mason GF, Rothman DL, Hyder F, Ciarcia JJ, Ostroff RB, Berman RM, Krystal JH. Increased cortical GABA concentrations in depressed patients receiving ECT. The American Journal of Psychiatry. 160: 577-9. PMID 12611844 DOI: 10.1176/Appi.Ajp.160.3.577  1
2003 Hoffman RE, Hawkins KA, Gueorguieva R, Boutros NN, Rachid F, Carroll K, Krystal JH. Transcranial magnetic stimulation of left temporoparietal cortex and medication-resistant auditory hallucinations. Archives of General Psychiatry. 60: 49-56. PMID 12511172 DOI: 10.1001/Archpsyc.60.1.49  1
2003 Rasmusson A, Guidotti A, Charney D, Vojvoda D, Lipschitz D, Weisman D, Krystal J. S.20.01 Adrenal & CSF neurosteroids as mediators of HPA axis upregulation and symptom production in premenopausal women with PTSD European Neuropsychopharmacology. 13. DOI: 10.1016/S0924-977X(03)91680-4  1
2003 Krystal J, D'Souza DH, Mathalon DH, Belger A, Perry E. S.01.03 Therapeutic implications of the NMDA receptor antagonist model psychosis European Neuropsychopharmacology. 13. DOI: 10.1016/S0924-977X(03)91600-2  1
2003 Qin J, Mitchell KJ, Johnson MK, Krystal JH, Southwick SM, Rasmusson AM, Allen ES. Reactions to and memories for the September 11, 2001 terrorist attacks in adults with posttraumatic stress disorder Applied Cognitive Psychology. 17: 1081-1097. DOI: 10.1002/Acp.987  1
2002 Blumberg HP, Charney DS, Krystal JH. Frontotemporal neural systems in bipolar disorder. Seminars in Clinical Neuropsychiatry. 7: 243-54. PMID 12382207 DOI: 10.1053/Scnp.2002.35220  1
2002 Krystal JH. Commentary: first, do no harm. Then, do some good: ethics and human experimental psychopharmacology. The Israel Journal of Psychiatry and Related Sciences. 39: 89-91. PMID 12227233  0.01
2002 Epperson CN, Haga K, Mason GF, Sellers E, Gueorguieva R, Zhang W, Weiss E, Rothman DL, Krystal JH. Cortical gamma-aminobutyric acid levels across the menstrual cycle in healthy women and those with premenstrual dysphoric disorder: a proton magnetic resonance spectroscopy study. Archives of General Psychiatry. 59: 851-8. PMID 12215085 DOI: 10.1001/Archpsyc.59.9.851  1
Show low-probability matches.