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Brandy L. Akin, Ph.D. - Publications

Affiliations: 
2010 Biochemistry and Molecular Biology Indiana University, Bloomington, Bloomington, IN, United States 
Area:
Molecular Biology, Biochemistry
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13 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2013 Akin BL, Hurley TD, Chen Z, Jones LR. The structural basis for phospholamban inhibition of the calcium pump in sarcoplasmic reticulum. The Journal of Biological Chemistry. 288: 30181-91. PMID 23996003 DOI: 10.1074/Jbc.M113.501585  0.743
2012 Akin BL, Jones LR. Characterizing phospholamban to sarco(endo)plasmic reticulum Ca2+-ATPase 2a (SERCA2a) protein binding interactions in human cardiac sarcoplasmic reticulum vesicles using chemical cross-linking. The Journal of Biological Chemistry. 287: 7582-93. PMID 22247554 DOI: 10.1074/Jbc.M111.334987  0.811
2012 Akin BL, Jones LR. Characterizing phospholamban to sarco(endo)plasmic reticulum Ca 2+-ATPase 2a (SERCA2a) protein binding interactions in human cardiac sarcoplasmic reticulum vesicles using chemical cross-linking (Journal of Biological Chemistry (2012) 287, (7582-7593)) Journal of Biological Chemistry. 287: 18586. DOI: 10.1074/Jbc.A111.334987  0.706
2011 Akin BL, Jones LR. Highly Specific, Conformationally-Dependent Cross-Linking of Lys27 of PLB to SERCA2a in Cardiac SR Vesicles from Humans Biophysical Journal. 100: 466a. DOI: 10.1016/J.Bpj.2010.12.2736  0.709
2010 Akin BL, Chen Z, Jones LR. Superinhibitory phospholamban mutants compete with Ca2+ for binding to SERCA2a by stabilizing a unique nucleotide-dependent conformational state. The Journal of Biological Chemistry. 285: 28540-52. PMID 20622261 DOI: 10.1074/Jbc.M110.151779  0.793
2010 Chen Z, Akin BL, Jones LR. Ca2+ binding to site I of the cardiac Ca2+ pump is sufficient to dissociate phospholamban. The Journal of Biological Chemistry. 285: 3253-60. PMID 19948724 DOI: 10.1074/Jbc.M109.080820  0.799
2009 Chopra N, Yang T, Asghari P, Moore ED, Huke S, Akin B, Cattolica RA, Perez CF, Hlaing T, Knollmann-Ritschel BE, Jones LR, Pessah IN, Allen PD, Franzini-Armstrong C, Knollmann BC. Ablation of triadin causes loss of cardiac Ca2+ release units, impaired excitation-contraction coupling, and cardiac arrhythmias. Proceedings of the National Academy of Sciences of the United States of America. 106: 7636-41. PMID 19383796 DOI: 10.1073/Pnas.0902919106  0.758
2009 Chen Z, Akin BL, Jones LR. Ca2+ Binding to Site I of the Cardiac Ca2+ Pump (SERCA2a) is Sufficient to Dissociate Phospholamban (PLB) Biophysical Journal. 96: 142a-143a. DOI: 10.1016/j.bpj.2008.12.635  0.782
2009 Akin BL, Chen Z, Jones LR. Cross-Linkable, Gain-of-Function Phospholamban (PLB) Mutant Reveals the Molecular Mechanism of SERCA2a Inhibition Biophysical Journal. 96: 210a-211a. DOI: 10.1016/J.Bpj.2008.12.1865  0.792
2007 Chopra N, Kannankeril PJ, Yang T, Hlaing T, Holinstat I, Ettensohn K, Pfeifer K, Akin B, Jones LR, Franzini-Armstrong C, Knollmann BC. Modest reductions of cardiac calsequestrin increase sarcoplasmic reticulum Ca2+ leak independent of luminal Ca2+ and trigger ventricular arrhythmias in mice. Circulation Research. 101: 617-26. PMID 17656677 DOI: 10.1161/Circresaha.107.157552  0.744
2007 Chen Z, Akin BL, Jones LR. Mechanism of reversal of phospholamban inhibition of the cardiac Ca2+-ATPase by protein kinase A and by anti-phospholamban monoclonal antibody 2D12. The Journal of Biological Chemistry. 282: 20968-76. PMID 17548345 DOI: 10.1074/Jbc.M703516200  0.785
2006 Knollmann BC, Chopra N, Hlaing T, Akin B, Yang T, Ettensohn K, Knollmann BE, Horton KD, Weissman NJ, Holinstat I, Zhang W, Roden DM, Jones LR, Franzini-Armstrong C, Pfeifer K. Casq2 deletion causes sarcoplasmic reticulum volume increase, premature Ca2+ release, and catecholaminergic polymorphic ventricular tachycardia. The Journal of Clinical Investigation. 116: 2510-20. PMID 16932808 DOI: 10.1172/Jci29128  0.759
2006 Chen Z, Akin BL, Stokes DL, Jones LR. Cross-linking of C-terminal residues of phospholamban to the Ca2+ pump of cardiac sarcoplasmic reticulum to probe spatial and functional interactions within the transmembrane domain. The Journal of Biological Chemistry. 281: 14163-72. PMID 16554295 DOI: 10.1074/Jbc.M601338200  0.693
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