| Year |
Citation |
Score |
| 2023 |
Wang Y, Li Q, Tao B, Angelini M, Ramadoss S, Sun B, Wang P, Krokhaleva Y, Ma F, Gu Y, Espinoza A, Yamauchi K, Pellegrini M, Novitch B, Olcese R, et al. Fibroblasts in heart scar tissue directly regulate cardiac excitability and arrhythmogenesis. Science (New York, N.Y.). 381: 1480-1487. PMID 37769108 DOI: 10.1126/science.adh9925 |
0.723 |
|
| 2023 |
Servettini I, Talani G, Megaro A, Setzu MD, Biggio F, Briffa M, Guglielmi L, Savalli N, Binda F, Delicata F, Bru-Mercier G, Vassallo N, Maglione V, Cauchi RJ, Di Pardo A, ... ... Olcese R, et al. An activator of voltage-gated K channels Kv1.1 as a therapeutic candidate for episodic ataxia type 1. Proceedings of the National Academy of Sciences of the United States of America. 120: e2207978120. PMID 37487086 DOI: 10.1073/pnas.2207978120 |
0.758 |
|
| 2023 |
Medzikovic L, Aryan L, Ruffenach G, Li M, Savalli N, Sun W, Sarji S, Hong J, Sharma S, Olcese R, Fishbein G, Eghbali M. Myocardial fibrosis and calcification are attenuated by microRNA-129-5p targeting Asporin and Sox9 in cardiac fibroblasts. Jci Insight. 8. PMID 37154157 DOI: 10.1172/jci.insight.168655 |
0.688 |
|
| 2023 |
Zyrianova T, Zou K, Lopez B, Liao A, Gu C, Olcese R, Schwingshackl A. Activation of Endothelial Large Conductance Potassium Channels Protects against TNF-α-Induced Inflammation. International Journal of Molecular Sciences. 24. PMID 36835507 DOI: 10.3390/ijms24044087 |
0.71 |
|
| 2023 |
Angelini M, McVicar M, Savalli N, John SA, Neely A, Pantazis A, Ottolia M, Olcese R. The voltage-dependent structural transitions governing the opening of the human t-type Cav3.1 channel: Insights from voltage-clamp fluorometry. Biophysical Journal. 122: 107a. PMID 36782464 DOI: 10.1016/j.bpj.2022.11.760 |
0.672 |
|
| 2022 |
Zyrianova T, Lopez B, Zou K, Gu C, Pham D, Talapaneni S, Waters CM, Olcese R, Schwingshackl A. Activation of TREK-1 (K2.1) Potassium Channels Protects Against Influenza A-Induced Lung Injury. American Journal of Physiology. Lung Cellular and Molecular Physiology. PMID 36410022 DOI: 10.1152/ajplung.00116.2022 |
0.629 |
|
| 2022 |
Nilsson M, Lindström SH, Kaneko M, Wang K, Minguez-Viñas T, Angelini M, Steccanella F, Holder D, Ottolia M, Olcese R, Pantazis A. An epilepsy-associated K1.2 charge-transfer-center mutation impairs K1.2 and K1.4 trafficking. Proceedings of the National Academy of Sciences of the United States of America. 119: e2113675119. PMID 35439054 DOI: 10.1073/pnas.2113675119 |
0.791 |
|
| 2022 |
Qu Z, Liu MB, Olcese R, Karagueuzian H, Garfinkel A, Chen PS, Weiss JN. R-on-T and the Initiation of Reentry Revisited: Integrating Old and New Concepts. Heart Rhythm. PMID 35364332 DOI: 10.1016/j.hrthm.2022.03.1224 |
0.351 |
|
| 2021 |
Angelini M, Pezhouman A, Savalli N, Chang MG, Steccanella F, Scranton K, Calmettes G, Ottolia M, Pantazis A, Karagueuzian HS, Weiss JN, Olcese R. Suppression of ventricular arrhythmias by targeting late L-type Ca2+ current. The Journal of General Physiology. 153. PMID 34698805 DOI: 10.1085/jgp.202012584 |
0.829 |
|
| 2021 |
Savalli N, Angelini M, Steccanella F, Wier J, Wu F, Quinonez M, DiFranco M, Neely A, Cannon SC, Olcese R. The distinct role of the four voltage sensors of the skeletal CaV1.1 channel in voltage-dependent activation. The Journal of General Physiology. 153. PMID 34546289 DOI: 10.1085/jgp.202112915 |
0.85 |
|
| 2020 |
Zyrianova T, Lopez B, Olcese R, Belperio J, Waters CM, Wong L, Nguyen V, Talapaneni S, Schwingshackl A. K2.1 (TREK-1) potassium channel activation protects against hyperoxia-induced lung injury. Scientific Reports. 10: 22011. PMID 33319831 DOI: 10.1038/s41598-020-78886-y |
0.687 |
|
| 2020 |
Zyrianova T, Lopez B, Liao A, Gu C, Wong L, Ottolia M, Olcese R, Schwingshackl A. BK Channels Regulate LPS-induced CCL-2 Release from Human Pulmonary Endothelial Cells. American Journal of Respiratory Cell and Molecular Biology. PMID 33217242 DOI: 10.1165/rcmb.2020-0228OC |
0.667 |
|
| 2020 |
Pantazis A, Kaneko M, Angelini M, Steccanella F, Westerlund AM, Lindström SH, Nilsson M, Delemotte L, Saitta SC, Olcese R. Tracking the motion of K 1.2 voltage sensor reveals the molecular perturbations caused by a de novo mutation in a case of epilepsy. The Journal of Physiology. PMID 32833227 DOI: 10.1113/Jp280438 |
0.816 |
|
| 2020 |
Landaw J, Zhang Z, Song Z, Liu MB, Olcese R, Chen PS, Weiss JN, Qu Z. Small-conductance Ca-activated K channels promote J-wave syndrome and phase-2 reentry. Heart Rhythm. PMID 32333974 DOI: 10.1016/J.Hrthm.2020.04.023 |
0.683 |
|
| 2020 |
Zyrianova T, Lopez B, Liao A, Gu C, Wong L, Ottolia M, Olcese R, Schwingshackl A. Large Conductance Ca2+-activated K+ Channels Regulate LPS-induced Cytokine Secretion from Alveolar Epithelial and Endothelial Cells Biophysical Journal. 118. DOI: 10.1016/J.Bpj.2019.11.997 |
0.721 |
|
| 2020 |
Savalli N, Angelini M, Steccanella F, Wu F, Quinonez M, Neely A, Cannon SC, Olcese R. The Contribution of the Individual Voltage Sensors to the Activation of Skeletal CaV1.1 Channels Biophysical Journal. 118: 105a. DOI: 10.1016/J.Bpj.2019.11.728 |
0.825 |
|
| 2020 |
Angelini M, Pezhouman A, Savalli N, Chang M, Calmettes G, Steccanella F, Pantazis A, Karagueuzian HS, Weiss JN, Olcese R. Potent Suppression of Ventricular Arrhythmias by Selectively Targeting Late L-type Calcium Current Biophysical Journal. 118: 104a. DOI: 10.1016/J.Bpj.2019.11.723 |
0.78 |
|
| 2020 |
Scranton K, Umar S, Calmettes G, Eghbali M, Goldhaber JI, John SA, Olcese R, Escobar AL, Ottolia M. The Na+-dependent Inactivation of NCX1.1 is Physiologically Relevant to Cardiac Function Biophysical Journal. 118: 100a-101a. DOI: 10.1016/J.Bpj.2019.11.707 |
0.555 |
|
| 2020 |
Steccanella F, Scranton K, Panday N, Angelini M, Zhang R, Lotteau S, John SA, Olcese R, Goldhaber JI, Ottolia M. Genetic Ablation of NCX1.1 Na+-dependent Inactivation Impacts Cardiac Action Potential and Ca2+ Transient Biophysical Journal. 118: 100a. DOI: 10.1016/J.Bpj.2019.11.706 |
0.801 |
|
| 2020 |
Steccanella F, Savalli N, Angelini M, Neely A, Olcese R. Differential Modulation of L-Type CaV1.1 and CaV1.2 Channels by the α2δ-1 Subunit Biophysical Journal. 118: 499a. DOI: 10.1016/J.Bpj.2019.11.2754 |
0.824 |
|
| 2020 |
Angelini M, Savalli N, Steccanella F, Di Franco MG, Neely A, Cannon SC, Olcese R. Which CaV1.1 Voltage Sensor(s) Activate RYR1? Biophysical Journal. 118: 498a. DOI: 10.1016/J.Bpj.2019.11.2752 |
0.786 |
|
| 2019 |
Seki S, Yamamoto T, Quinn K, Spigelman I, Pantazis A, Olcese R, Wiedau-Pazos M, Chandler SH, Venugopal S. Circuit-Specific Early Impairment of Proprioceptive Sensory Neurons in the SOD1 Mouse Model for ALS. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. PMID 31530644 DOI: 10.1523/Jneurosci.1214-19.2019 |
0.579 |
|
| 2019 |
Venugopal S, Seki S, Terman DH, Pantazis A, Olcese R, Wiedau-Pazos M, Chandler SH. Resurgent Na+ Current Offers Noise Modulation in Bursting Neurons. Plos Computational Biology. 15: e1007154. PMID 31226124 DOI: 10.1371/Journal.Pcbi.1007154 |
0.62 |
|
| 2019 |
Balderas E, Torres NS, Rosa-Garrido M, Chaudhuri D, Toro L, Stefani E, Olcese R. MitoBK channel is functionally associated with its regulatory β1 subunit in cardiac mitochondria. The Journal of Physiology. PMID 31173379 DOI: 10.1113/Jp277769 |
0.719 |
|
| 2019 |
Steccanella F, Savalli N, Yusifov T, Battista Luciani G, Neely A, Olcese R. How Does the α2δ-1 Subunit Modulate Skeletal CaV1.1 Channels? Biophysical Journal. 116: 113a. DOI: 10.1016/J.Bpj.2018.11.639 |
0.829 |
|
| 2019 |
Angelini M, Savalli N, Yusifov T, Olcese R. Skeletal γ1 Subunit Modulation of Human CaV1.1 and CaV1.2 Channels Biophysical Journal. 116: 112a-113a. DOI: 10.1016/J.Bpj.2018.11.637 |
0.828 |
|
| 2019 |
Savalli N, Wu F, Quinonez M, Cannon SC, Olcese R. A Mutation Linked to Malignant Hyperthermia in the Skeletal CaV1.1 Channel Stabilizes the Resting State of Voltage Sensor I and Impairs Channel Activation Biophysical Journal. 116: 111a. DOI: 10.1016/J.Bpj.2018.11.629 |
0.773 |
|
| 2019 |
Pantazis A, Kaneko M, Westerlund AM, Delemotte L, Saitta S, Olcese R. A De Novo Mutation Associated with Epilepsy Enhances KV1.2 Voltage Dependence, Suppressing Neuronal Excitability Biophysical Journal. 116: 247a. DOI: 10.1016/J.Bpj.2018.11.1351 |
0.608 |
|
| 2018 |
Pantazis A, Westerberg K, Althoff T, Abramson J, Olcese R. Harnessing photoinduced electron transfer to optically determine protein sub-nanoscale atomic distances. Nature Communications. 9: 4738. PMID 30413716 DOI: 10.1038/S41467-018-07218-6 |
0.652 |
|
| 2018 |
John S, Kim B, Olcese R, Goldhaber JI, Ottolia M. Molecular determinants of pH regulation in the cardiac Na+-Ca2+ exchanger. The Journal of General Physiology. PMID 29301861 DOI: 10.1085/Jgp.201611693 |
0.392 |
|
| 2018 |
Angelini M, Pezhouman A, Chang MG, Savalli N, Calmettes G, Pantazis A, Karagueuzian HS, Weiss JN, Olcese R. L-Type Calcium Channel Gating Modifiers as a New Class of Antiarrhythmic Drugs Biophysical Journal. 114: 623a. DOI: 10.1016/J.Bpj.2017.11.3370 |
0.819 |
|
| 2018 |
Pantazis A, Olcese R. Resolving the BK Channel Voltage Sensor Activation Transition with Relative Atomic Coordinates Under Physiologically-Relevant Conditions Biophysical Journal. 114: 545a. DOI: 10.1016/J.Bpj.2017.11.2980 |
0.685 |
|
| 2018 |
Savalli N, Wu F, Quinonez M, Cannon SC, Olcese R. Optically-Tracked Structural Rearrangements of the Voltage Sensing Domains in the Human CaV1.1 Channel Biophysical Journal. 114: 39a. DOI: 10.1016/J.Bpj.2017.11.265 |
0.749 |
|
| 2017 |
Schwingshackl A, Lopez B, Teng B, Luellen CL, Lesage F, Belperio J, Olcese R, Waters CM. Hyperoxia treatment of TREK-1/TREK-2/TRAAK-deficient mice is associated with a reduction in surfactant proteins. American Journal of Physiology. Lung Cellular and Molecular Physiology. ajplung.00121.2017. PMID 28839101 DOI: 10.1152/Ajplung.00121.2017 |
0.614 |
|
| 2017 |
Karagueuzian HS, Pezhouman A, Angelini M, Olcese R. Enhanced Late Na and Ca Currents as Effective Antiarrhythmic Drug Targets. Frontiers in Pharmacology. 8: 36. PMID 28220073 DOI: 10.3389/Fphar.2017.00036 |
0.771 |
|
| 2017 |
Yusifov T, Savalli N, Pantazis A, Heinemann SH, Hoshi T, Olcese R. Carbon Monoxide May Regulate BK slo1 Channel Activity by Partially Disrupting Heme Coordination Biophysical Journal. 112: 112a. DOI: 10.1016/J.Bpj.2016.11.631 |
0.823 |
|
| 2017 |
Contreras GF, Savalli N, Pantazis A, Gonzalez C, Olcese R, Neely A. The Calcium Channel A2D Subunit Increases the Gating Charges of Ca v 1.2 Channels Biophysical Journal. 112: 108a. DOI: 10.1016/J.Bpj.2016.11.614 |
0.844 |
|
| 2017 |
John S, Kim B, Olcese R, Goldhaber JI, Ottolia M. Proton Sensitivity of NCX: Modulation by Na, Ca and a Distinct Proton-Sensing Domain Biophysical Journal. 112: 275a. DOI: 10.1016/J.Bpj.2016.11.1488 |
0.394 |
|
| 2017 |
Pantazis A, Sigg D, Neely A, Olcese R. Optically Probing the Mechanism of Voltage-Dependent Facilitation in Ca V 1.2 Channels Biophysical Journal. 112: 244a-245a. DOI: 10.1016/J.Bpj.2016.11.1337 |
0.744 |
|
| 2017 |
Angelini M, Pezhouman A, Savalli N, Pantazis A, Karagueuzian HS, Weiss JN, Olcese R. A New Class of Antiarrhythmics for Late I CA,L Biophysical Journal. 112: 234a-235a. DOI: 10.1016/J.Bpj.2016.11.1285 |
0.818 |
|
| 2016 |
Zhang J, Li M, Zhang Z, Zhu R, Olcese R, Stefani E, Toro L. The mitochondrial BKCa channel cardiac interactome reveals BKCa association with the mitochondrial import receptor subunit Tom22, and the adenine nucleotide translocator. Mitochondrion. PMID 27592226 DOI: 10.1016/J.Mito.2016.08.017 |
0.678 |
|
| 2016 |
Savalli N, Pantazis A, Sigg D, Weiss JN, Neely A, Olcese R. The α2δ-1 subunit remodels CaV1.2 voltage sensors and allows Ca2+ influx at physiological membrane potentials. The Journal of General Physiology. 148: 147-59. PMID 27481713 DOI: 10.1085/Jgp.201611586 |
0.867 |
|
| 2016 |
Pantazis A, Olcese R. Biophysics of BK Channel Gating. International Review of Neurobiology. 128: 1-49. PMID 27238260 DOI: 10.1016/Bs.Irn.2016.03.013 |
0.742 |
|
| 2016 |
Pantazis A, Olcese R. Distance-Resolving Voltage Clamp Fluorometry (drVCF) Quantifies Intramolecular Transitions in the Human BK and CI-VSP Voltage Sensors Under Physiologically-Relevant Conditions Biophysical Journal. 110: 103a. DOI: 10.1016/J.Bpj.2015.11.615 |
0.635 |
|
| 2016 |
Savalli N, Angelini M, Weiss JN, Olcese R. Gabapentinoids Suppress Early Afterdepolarizations by Uncoupling α2δ-1 Subunits from CAV1.2 Channels: Implications for CAV Channel Gating-Modifiers as a New Class of Antiarrhythmics Biophysical Journal. 110: 34a. DOI: 10.1016/J.Bpj.2015.11.252 |
0.864 |
|
| 2016 |
De Giorgis D, Contreras G, Savalli N, Navarro-Quezada N, Gonzalez C, Olcese R, Neely A. Regulation of Voltage Sensing Structures of CaV1.2 Calcium Channels by the Auxiliary β-Subunit (β3) Biophysical Journal. 110: 444a. DOI: 10.1016/J.Bpj.2015.11.2390 |
0.846 |
|
| 2016 |
Savalli N, Angelini M, Pantazis A, Yusifov T, Neely A, Olcese R. Eminence of VSD I in the Voltage-Dependent Inactivation of the Human CaV1.2 Channel Biophysical Journal. 110: 444a. DOI: 10.1016/J.Bpj.2015.11.2388 |
0.855 |
|
| 2016 |
Wu X, Wu Y, Olcese R, Toro L, Stefani E. A New Iterative Deep Neural Network Algorithm to Significantly Improve Image Segmentation Biophysical Journal. 110: 331a. DOI: 10.1016/J.Bpj.2015.11.1780 |
0.587 |
|
| 2016 |
Zhang J, Zhang Z, Zhu R, Li M, Lu R, Wu Y, Olcese R, Stefani E, Toro L. BK Channel Subproteome Includes Novel Mitochondrial Partners: ADP/ATP Carrier and TOM 22 Import Receptor Biophysical Journal. 110: 279a. DOI: 10.1016/J.Bpj.2015.11.1513 |
0.687 |
|
| 2016 |
Balderas Angeles E, Olcese R, Toro L, Stefani E. Mouse Cardiac MitobkCa Associates with β1 Subunit Favoring Channel Expression and Activity Biophysical Journal. 110: 279a. DOI: 10.1016/J.Bpj.2015.11.1512 |
0.725 |
|
| 2016 |
Angelini M, Pezhouman A, Savalli N, Pantazis A, Melkonian A, Weiss JN, Karagueuzian HS, Olcese R. Roscovitine as the Archetypal Member of a Novel Class of Antiarrhythmics Targeting Late ICa,L Biophysical Journal. 110: 272a. DOI: 10.1016/J.Bpj.2015.11.1478 |
0.803 |
|
| 2015 |
Prudat Y, Madhvani RV, Angelini M, Borgstom NP, Garfinkel A, Karagueuzian HS, Weiss JN, de Lange E, Olcese R, Kucera JP. Stochastic pacing reveals the propensity to cardiac action potential alternans and uncovers its underlying dynamics. The Journal of Physiology. PMID 26563830 DOI: 10.1113/Jp271573 |
0.813 |
|
| 2015 |
Madhvani RV, Angelini M, Xie Y, Pantazis A, Suriany S, Borgstrom NP, Garfinkel A, Qu Z, Weiss JN, Olcese R. Targeting the late component of the cardiac L-type Ca2+ current to suppress early afterdepolarizations. The Journal of General Physiology. 145: 395-404. PMID 25918358 DOI: 10.1085/Jgp.201411288 |
0.834 |
|
| 2015 |
Weiss JN, Garfinkel A, Karagueuzian HS, Nguyen TP, Olcese R, Chen PS, Qu Z. Perspective: a dynamics-based classification of ventricular arrhythmias. Journal of Molecular and Cellular Cardiology. 82: 136-52. PMID 25769672 DOI: 10.1016/J.Yjmcc.2015.02.017 |
0.474 |
|
| 2015 |
Yusifov T, Savalli N, Heinemann SH, Hoshi T, Olcese R. The Heme-Bound Human BK Channel Gating Ring is a Co Sensor Biophysical Journal. 108: 122a. DOI: 10.1016/J.Bpj.2014.11.682 |
0.843 |
|
| 2015 |
Yusifov T, Savalli N, Park S, Pantazis A, Olcese R. The Role of Met-691 in Heme-Dependent Regulation Supports the Presence of a Cytochrome-C-Like Structure in Human BK Channels Biophysical Journal. 108: 121a-122a. DOI: 10.1016/J.Bpj.2014.11.681 |
0.843 |
|
| 2015 |
Savalli N, Pantazis A, Sigg D, Neely A, Olcese R. The α2δ Subunit Efficiently Couples VSDs Activation to Pore Opening in Human Cav1.2 Channels Biophysical Journal. 108: 581a. DOI: 10.1016/J.Bpj.2014.11.3173 |
0.843 |
|
| 2015 |
Savalli N, Sigg D, Neely A, Olcese R. β2A and β3 Differentially Modulate Time- and Voltage-Dependent Properties of Individual Voltage Sensors in the Human Cav1.2 Channel Biophysical Journal. 108: 581a. DOI: 10.1016/J.Bpj.2014.11.3172 |
0.761 |
|
| 2015 |
Pantazis A, Olcese R. Enhanced Voltage-Clamp Fluorometry Assigns Distance Constraints to BK Channel VSD Structural Transitions Biophysical Journal. 108: 23a. DOI: 10.1016/J.Bpj.2014.11.152 |
0.628 |
|
| 2014 |
Pantazis A, Savalli N, Sigg D, Neely A, Olcese R. Functional heterogeneity of the four voltage sensors of a human L-type calcium channel. Proceedings of the National Academy of Sciences of the United States of America. 111: 18381-6. PMID 25489110 DOI: 10.1073/Pnas.1411127112 |
0.858 |
|
| 2014 |
Savalli N, Pantazis A, Sigg D, Neely A, Olcese R. The α2δ Subunit Facilitates CaV1.2 Channel Activation by Remodeling Its Four Voltage Sensor Domains Biophysical Journal. 106: 135a. DOI: 10.1016/J.Bpj.2013.11.791 |
0.846 |
|
| 2014 |
Sigg D, Shieh R, Pantazis A, Savalli N, Olcese R. Hill Analysis of Ion Channel Activation: Theory and Practice Biophysical Journal. 106: 134a-135a. DOI: 10.1016/J.Bpj.2013.11.789 |
0.792 |
|
| 2014 |
Pantazis A, Savalli N, Sigg D, Neely A, Olcese R. The Functional Heterogeneity of the Human CaV1.2 Voltage Sensors Biophysical Journal. 106: 134a. DOI: 10.1016/J.Bpj.2013.11.786 |
0.821 |
|
| 2014 |
Yusifov T, Savalli N, Pantazis A, Olcese R. Enzymatic Activity of the Human BK Channel: A Function Beyond Electrical Signaling Biophysical Journal. 106: 535a. DOI: 10.1016/J.Bpj.2013.11.2986 |
0.837 |
|
| 2014 |
Yusifov T, Madhvani RV, Olcese R. The Cytochrome C-Like Domain of the Human BK Channel Biophysical Journal. 106: 535a. DOI: 10.1016/J.Bpj.2013.11.2985 |
0.817 |
|
| 2014 |
Savalli N, Pantazis A, Sigg D, Neely A, Olcese R. A Timothy Syndrome Causing Mutation Perturbs Voltage Sensor Operation in Human CaV1.2 Channels Biophysical Journal. 106: 330a-331a. DOI: 10.1016/J.Bpj.2013.11.1898 |
0.844 |
|
| 2013 |
Hoshi T, Pantazis A, Olcese R. Transduction of voltage and Ca2+ signals by Slo1 BK channels. Physiology (Bethesda, Md.). 28: 172-89. PMID 23636263 DOI: 10.1152/Physiol.00055.2012 |
0.748 |
|
| 2013 |
Qu Z, Xie LH, Olcese R, Karagueuzian HS, Chen PS, Garfinkel A, Weiss JN. Early afterdepolarizations in cardiac myocytes: beyond reduced repolarization reserve. Cardiovascular Research. 99: 6-15. PMID 23619423 DOI: 10.1093/Cvr/Cvt104 |
0.548 |
|
| 2013 |
Yusifov T, Gandhi CS, Pantazis A, Olcese R. Structural Studies of the Apo and Ca2+-Bound States of the Human BK (SLO1) Channel Gating Ring in Solution Biophysical Journal. 104: 473a. DOI: 10.1016/J.Bpj.2012.11.2614 |
0.817 |
|
| 2013 |
Savalli N, Sun X, Peskoff A, Yazejian B, Olcese R, Grinnell AD. Using CaV-Type Dependent BK Channel Behavior to Probe BK-CaV Channel Coupling and Submembrane [Ca2+] Dynamics Biophysical Journal. 104: 471a. DOI: 10.1016/J.Bpj.2012.11.2601 |
0.805 |
|
| 2013 |
Pantazis A, Savalli N, Neely A, Olcese R. Optically-Resolved Conformational Rearrangements of the Voltage-Sensing Domains of the Human CaV1.2 Channel Biophysical Journal. 104: 358a-359a. DOI: 10.1016/J.Bpj.2012.11.1992 |
0.865 |
|
| 2013 |
Madhvani RV, Xie Y, Pantazis A, Garfinkel A, Qu Z, Weiss JN, Olcese R. Tuning L-Type Ca2+ Current Properties to Suppress Early After depolarizations Biophysical Journal. 104: 295a. DOI: 10.1016/J.Bpj.2012.11.1646 |
0.826 |
|
| 2013 |
Pantazis A, Savalli N, Olcese R. The Activation Transition of the Human BK (Slo1) Voltage Sensor Involves a Complex Rearrangement of its Helix Bundle as Resolved by Site-Directed Fluorophore/Quencher Pairs Biophysical Journal. 104: 197a. DOI: 10.1016/J.Bpj.2012.11.1112 |
0.811 |
|
| 2012 |
Pantazis A, Olcese R. Relative transmembrane segment rearrangements during BK channel activation resolved by structurally assigned fluorophore-quencher pairing. The Journal of General Physiology. 140: 207-18. PMID 22802360 DOI: 10.1085/Jgp.201210807 |
0.698 |
|
| 2012 |
Savalli N, Pantazis A, Yusifov T, Sigg D, Olcese R. The contribution of RCK domains to human BK channel allosteric activation. The Journal of Biological Chemistry. 287: 21741-50. PMID 22556415 DOI: 10.1074/Jbc.M112.346171 |
0.848 |
|
| 2012 |
Pantazis A, Xu L, Sigg D, Olcese R. Probing the Allosteric Interactions that Mediate Voltage-Dependent BK (Slo1) Channel Activation with a Pore Blocker Biophysical Journal. 102: 688a. DOI: 10.1016/J.Bpj.2011.11.3740 |
0.754 |
|
| 2012 |
Pantazis A, Olcese R. The Mechanics of Voltage Sensing in the Human BK Channel (Slo1) Biophysical Journal. 102: 688a. DOI: 10.1016/J.Bpj.2011.11.3739 |
0.711 |
|
| 2012 |
Yusifov T, Javaherian AD, Heinemann SH, Hoshi T, Olcese R. Evidence for Lipid-Induced Structural Rearrangements in the Human BK (Slo1) Channel Gating Ring Biophysical Journal. 102: 688a. DOI: 10.1016/J.Bpj.2011.11.3738 |
0.762 |
|
| 2012 |
Yusifov T, Javaherian AD, Heinemann SH, Hoshi T, Olcese R. Calcium and Heme Induce Distinct Conformational States of the Human BK (Slo1) Channel Gating Ring Biophysical Journal. 102: 687a-688a. DOI: 10.1016/J.Bpj.2011.11.3737 |
0.737 |
|
| 2012 |
Savalli N, Kohanteb AP, Yazejian B, Olcese R, Peskoff A, Grinnell AD. BK and CaV Channel Interactions in the Plasma Membrane Biophysical Journal. 102: 687a. DOI: 10.1016/J.Bpj.2011.11.3736 |
0.807 |
|
| 2012 |
Madhvani RV, Xie Y, Pantazis A, Garfinkel A, Qu Z, Weiss JN, Olcese R. How do L-Type Calcium Current Kinetics Contribute to Early After Depolarizations in Cardiac Myocytes? Biophysical Journal. 102: 541a. DOI: 10.1016/J.Bpj.2011.11.2956 |
0.808 |
|
| 2011 |
Madhvani RV, Xie Y, Pantazis A, Garfinkel A, Qu Z, Weiss JN, Olcese R. Shaping a new Ca²⺠conductance to suppress early afterdepolarizations in cardiac myocytes. The Journal of Physiology. 589: 6081-92. PMID 22025660 DOI: 10.1113/Jphysiol.2011.219600 |
0.82 |
|
| 2011 |
Olcese R. I(KACh) at the whim of a capricious M2R. The Journal of Physiology. 589: 1869-70. PMID 21498381 DOI: 10.1113/Jphysiol.2011.207951 |
0.482 |
|
| 2011 |
Javaherian AD, Yusifov T, Pantazis A, Franklin S, Gandhi CS, Olcese R. Metal-driven operation of the human large-conductance voltage- and Ca2+-dependent potassium channel (BK) gating ring apparatus. The Journal of Biological Chemistry. 286: 20701-9. PMID 21471215 DOI: 10.1074/Jbc.M111.235234 |
0.83 |
|
| 2011 |
Sigg DM, Olcese R. Modular Allosterism in Potassium Channels Biophysical Journal. 100. DOI: 10.1016/J.Bpj.2010.12.3361 |
0.492 |
|
| 2011 |
Pantazis A, Kohanteb A, Olcese R. Probing the Dynamic Structure of the BKCa Voltage Sensor: Relative Motion of Segments S0 & S4 During Activation Biophysical Journal. 100: 581a. DOI: 10.1016/J.Bpj.2010.12.3360 |
0.7 |
|
| 2011 |
Yusifov T, Javaherian A, Pantazis A, Gandhi C, Olcese R. On the Properties of the RCK1 Domain of the Human BK (SLO1) Channel Biophysical Journal. 100: 581a. DOI: 10.1016/J.Bpj.2010.12.3359 |
0.798 |
|
| 2011 |
Yusifov T, Javaherian A, Gandhi C, Olcese R. Calcium-Dependent Operation of the Human BK Channel Gating Ring Apparatus Biophysical Journal. 100: 581a. DOI: 10.1016/J.Bpj.2010.12.3358 |
0.785 |
|
| 2011 |
Madhvani RV, Xie Y, Pantazis A, Garfinkel A, Qu Z, Weiss JN, Olcese R. Suppressing Early Afterdepolarizations in Cardiac Myocytes by Shaping a Modified Ca2+ Conductance Under Dynamic Clamp Biophysical Journal. 100: 439a. DOI: 10.1016/J.Bpj.2010.12.2584 |
0.821 |
|
| 2010 |
Pantazis A, Kohanteb AP, Olcese R. Relative motion of transmembrane segments S0 and S4 during voltage sensor activation in the human BK(Ca) channel. The Journal of General Physiology. 136: 645-57. PMID 21078868 DOI: 10.1085/Jgp.201010503 |
0.718 |
|
| 2010 |
Yusifov T, Javaherian AD, Pantazis A, Gandhi CS, Olcese R. The RCK1 domain of the human BKCa channel transduces Ca2+ binding into structural rearrangements. The Journal of General Physiology. 136: 189-202. PMID 20624858 DOI: 10.1085/Jgp.200910374 |
0.814 |
|
| 2010 |
Pantazis A, Gudzenko V, Savalli N, Sigg D, Olcese R. Operation of the voltage sensor of a human voltage- and Ca2+-activated K+ channel. Proceedings of the National Academy of Sciences of the United States of America. 107: 4459-64. PMID 20160086 DOI: 10.1073/Pnas.0911959107 |
0.838 |
|
| 2010 |
Pantazis A, Kohanteb A, Olcese R. Voltage-Dependent Motions Reported from the N-Terminal Region in Human Slo1 BKCa Channels: S0 and Voltage Sensor Operation Biophysical Journal. 98: 127a. DOI: 10.1016/J.Bpj.2009.12.688 |
0.725 |
|
| 2010 |
Yusifov T, Javaherian A, Gandhi C, Hou S, Heinemann S, Hoshi T, Olcese R. Heme-Driven Conformational Changes in the Human Slo1 BKCa Channel Gating Ring Biophysical Journal. 98: 126a. DOI: 10.1016/J.Bpj.2009.12.684 |
0.765 |
|
| 2009 |
Olcese R. It's spring-time for slow inactivation. The Journal of General Physiology. 134: 457-9. PMID 19917731 DOI: 10.1085/Jgp.200910353 |
0.43 |
|
| 2009 |
Yusifov T, Javaherian A, Nicoll D, Gandhi C, Olcese R. Calcium Sensing Properties of the RCK1 Domain of the Human BK Channel: Effects of the D362/367A Mutation Biophysical Journal. 96: 481a. DOI: 10.1016/J.Bpj.2008.12.2482 |
0.757 |
|
| 2009 |
Javaherian A, Yusifov T, Nicoll D, Gandhi C, Olcese R. Structural and Functional Analysis of the Purified Cytosolic C-Terminus of the Human BK Channel Biophysical Journal. 96: 481a. DOI: 10.1016/J.Bpj.2008.12.2481 |
0.745 |
|
| 2009 |
Pantazis A, Gudzenko V, Savalli N, Kohanteb A, Sigg D, Olcese R. Cooperativity Between Voltage-sensing Domains in the Human BK Channel Revealed by Voltage-clamp Fluorometry. Biophysical Journal. 96: 481a. DOI: 10.1016/J.Bpj.2008.12.2480 |
0.825 |
|
| 2008 |
Gandhi CS, Olcese R. The voltage-clamp fluorometry technique. Methods in Molecular Biology (Clifton, N.J.). 491: 213-31. PMID 18998096 DOI: 10.1007/978-1-59745-526-8_17 |
0.49 |
|
| 2008 |
Yusifov T, Savalli N, Gandhi CS, Ottolia M, Olcese R. The RCK2 domain of the human BKCa channel is a calcium sensor. Proceedings of the National Academy of Sciences of the United States of America. 105: 376-81. PMID 18162557 DOI: 10.1073/Pnas.0705261105 |
0.842 |
|
| 2008 |
Mahajan A, Sato D, Shiferaw Y, Baher A, Xie LH, Peralta R, Olcese R, Garfinkel A, Qu Z, Weiss JN. Modifying L-type calcium current kinetics: consequences for cardiac excitation and arrhythmia dynamics. Biophysical Journal. 94: 411-23. PMID 18160661 DOI: 10.1529/Biophysj.106.98590 |
0.588 |
|
| 2008 |
Mahajan A, Shiferaw Y, Sato D, Baher A, Olcese R, Xie LH, Yang MJ, Chen PS, Restrepo JG, Karma A, Garfinkel A, Qu Z, Weiss JN. A rabbit ventricular action potential model replicating cardiac dynamics at rapid heart rates. Biophysical Journal. 94: 392-410. PMID 18160660 DOI: 10.1529/Biophysj.106.98160 |
0.579 |
|
| 2007 |
Savalli N, Kondratiev A, de Quintana SB, Toro L, Olcese R. Modes of operation of the BKCa channel beta2 subunit. The Journal of General Physiology. 130: 117-31. PMID 17591990 DOI: 10.1085/Jgp.200709803 |
0.828 |
|
| 2007 |
Gudzenko V, Shiferaw Y, Savalli N, Vyas R, Weiss JN, Olcese R. Influence of channel subunit composition on L-type Ca2+ current kinetics and cardiac wave stability. American Journal of Physiology. Heart and Circulatory Physiology. 293: H1805-15. PMID 17545475 DOI: 10.1152/Ajpheart.01160.2006 |
0.799 |
|
| 2007 |
Olcese R. And yet it moves: conformational States of the Ca2+ channel pore. The Journal of General Physiology. 129: 457-9. PMID 17535958 DOI: 10.1085/Jgp.200709814 |
0.463 |
|
| 2006 |
Savalli N, Kondratiev A, Toro L, Olcese R. Voltage-dependent conformational changes in human Ca(2+)- and voltage-activated K(+) channel, revealed by voltage-clamp fluorometry. Proceedings of the National Academy of Sciences of the United States of America. 103: 12619-24. PMID 16895996 DOI: 10.1073/Pnas.0601176103 |
0.833 |
|
| 2006 |
Mahajan A, Shiferaw Y, Xie L, Baher A, Olcese R, Qu Z, Weiss JN. P4-27 Heart Rhythm. 3: S227. DOI: 10.1016/J.Hrthm.2006.02.682 |
0.4 |
|
| 2004 |
Haug T, Olcese R, Toro L, Stefani E. Regulation of K+ flow by a ring of negative charges in the outer pore of BKCa channels. Part II: Neutralization of aspartate 292 reduces long channel openings and gating current slow component. The Journal of General Physiology. 124: 185-97. PMID 15277579 DOI: 10.1085/Jgp.200308950 |
0.772 |
|
| 2004 |
Haug T, Sigg D, Ciani S, Toro L, Stefani E, Olcese R. Regulation of K+ flow by a ring of negative charges in the outer pore of BKCa channels. Part I: Aspartate 292 modulates K+ conduction by external surface charge effect. The Journal of General Physiology. 124: 173-84. PMID 15277578 DOI: 10.1085/Jgp.200308949 |
0.735 |
|
| 2003 |
Latorre R, Olcese R, Basso C, Gonzalez C, Munoz F, Cosmelli D, Alvarez O. Molecular coupling between voltage sensor and pore opening in the Arabidopsis inward rectifier K+ channel KAT1. The Journal of General Physiology. 122: 459-69. PMID 14517271 DOI: 10.1085/Jgp.200308818 |
0.567 |
|
| 2003 |
Chang CS, Olcese R, Olsen RW. A single M1 residue in the beta2 subunit alters channel gating of GABAA receptor in anesthetic modulation and direct activation. The Journal of Biological Chemistry. 278: 42821-8. PMID 12939268 DOI: 10.1074/Jbc.M306978200 |
0.378 |
|
| 2002 |
Eghbali M, Olcese R, Zarei MM, Toro L, Stefani E. External pore collapse as an inactivation mechanism for Kv4.3 K+ channels. The Journal of Membrane Biology. 188: 73-86. PMID 12172648 DOI: 10.1007/S00232-001-0173-3 |
0.768 |
|
| 2002 |
Helguera G, Olcese R, Song M, Toro L, Stefani E. Tissue-specific regulation of Ca(2+) channel protein expression by sex hormones. Biochimica Et Biophysica Acta. 1569: 59-66. PMID 11853958 DOI: 10.1016/S0304-4165(01)00234-3 |
0.64 |
|
| 2002 |
Stefani E, Haug T, Ciani S, Toro L, Olcese R. Conduction of K Ions through BKCa Channels Is Enhanced by a Negatively Charged Residue near the Pore (D292) Anesthesiology. 96: A809. DOI: 10.1097/00000542-200209002-00809 |
0.684 |
|
| 2002 |
Olcese R, Zhu N, Haug T, Toro L, Stefani E. Conformational Changes in BK(Ca) Channel during Channel Opening and Closing Revealed by Optical Methods Anesthesiology. 96: A770. DOI: 10.1097/00000542-200209002-00770 |
0.747 |
|
| 2001 |
Song M, Helguera G, Eghbali M, Zhu N, Zarei MM, Olcese R, Toro L, Stefani E. Remodeling of Kv4.3 potassium channel gene expression under the control of sex hormones. The Journal of Biological Chemistry. 276: 31883-90. PMID 11427525 DOI: 10.1074/Jbc.M101058200 |
0.758 |
|
| 2001 |
Olcese R, Sigg D, Latorre R, Bezanilla F, Stefani E. A conducting state with properties of a slow inactivated state in a shaker K(+) channel mutant. The Journal of General Physiology. 117: 149-63. PMID 11158167 DOI: 10.1085/Jgp.117.2.149 |
0.663 |
|
| 2000 |
Platano D, Qin N, Noceti F, Birnbaumer L, Stefani E, Olcese R. Expression of the alpha(2)delta subunit interferes with prepulse facilitation in cardiac L-type calcium channels. Biophysical Journal. 78: 2959-72. PMID 10827975 DOI: 10.1016/S0006-3495(00)76835-4 |
0.572 |
|
| 1999 |
Song M, Zhu N, Olcese R, Barila B, Toro L, Stefani E. Hormonal control of protein expression and mRNA levels of the MaxiK channel alpha subunit in myometrium. Febs Letters. 460: 427-32. PMID 10556510 DOI: 10.1016/S0014-5793(99)01394-0 |
0.72 |
|
| 1999 |
Qin N, Olcese R, Bransby M, Lin T, Birnbaumer L. Ca2+-induced inhibition of the cardiac Ca2+ channel depends on calmodulin. Proceedings of the National Academy of Sciences of the United States of America. 96: 2435-8. PMID 10051660 DOI: 10.1073/Pnas.96.5.2435 |
0.466 |
|
| 1998 |
Qin N, Olcese R, Stefani E, Birnbaumer L. Modulation of human neuronal α-type calcium channel by αδ-subunit. American Journal of Physiology. Cell Physiology. 274: C1324-C1331. PMID 29591061 DOI: 10.1152/ajpcell.1998.274.5.C1324 |
0.624 |
|
| 1998 |
Birnbaumer L, Qin N, Olcese R, Tareilus E, Platano D, Costantin J, Stefani E. Structures and functions of calcium channel beta subunits. Journal of Bioenergetics and Biomembranes. 30: 357-75. PMID 9758332 DOI: 10.1023/A:1021989622656 |
0.61 |
|
| 1998 |
Ottolia M, Platano D, Qin N, Noceti F, Birnbaumer M, Toro L, Birnbaumer L, Stefani E, Olcese R. Functional coupling between human E-type Ca2+ channels and mu opioid receptors expressed in Xenopus oocytes. Febs Letters. 427: 96-102. PMID 9613607 DOI: 10.1016/S0014-5793(98)00401-3 |
0.683 |
|
| 1998 |
Qin N, Olcese R, Stefani E, Birnbaumer L. Modulation of human neuronal alpha 1E-type calcium channel by alpha 2 delta-subunit. The American Journal of Physiology. 274: C1324-31. PMID 9612220 DOI: 10.1152/Ajpcell.1998.274.5.C1324 |
0.599 |
|
| 1998 |
Roux MJ, Olcese R, Toro L, Bezanilla F, Stefani E. Fast inactivation in Shaker K+ channels. Properties of ionic and gating currents. The Journal of General Physiology. 111: 625-38. PMID 9565401 DOI: 10.1085/Jgp.111.5.625 |
0.739 |
|
| 1998 |
Qin N, Platano D, Olcese R, Costantin JL, Stefani E, Birnbaumer L. Unique regulatory properties of the type 2a Ca2+ channel beta subunit caused by palmitoylation. Proceedings of the National Academy of Sciences of the United States of America. 95: 4690-5. PMID 9539800 DOI: 10.1073/Pnas.95.8.4690 |
0.676 |
|
| 1998 |
Noceti F, Olcese R, Qin N, Zhou J, Stefani E. Effect of bay K 8644 (-) and the beta2a subunit on Ca2+-dependent inactivation in alpha1C Ca2+ channels. The Journal of General Physiology. 111: 463-75. PMID 9482712 DOI: 10.1085/Jgp.111.3.463 |
0.676 |
|
| 1997 |
Olcese R, Latorre R, Toro L, Bezanilla F, Stefani E. Correlation between charge movement and ionic current during slow inactivation in Shaker K+ channels. The Journal of General Physiology. 110: 579-89. PMID 9348329 DOI: 10.1085/Jgp.110.5.579 |
0.763 |
|
| 1997 |
Qin N, Platano D, Olcese R, Stefani E, Birnbaumer L. Direct interaction of gbetagamma with a C-terminal gbetagamma-binding domain of the Ca2+ channel alpha1 subunit is responsible for channel inhibition by G protein-coupled receptors. Proceedings of the National Academy of Sciences of the United States of America. 94: 8866-71. PMID 9238069 DOI: 10.1073/Pnas.94.16.8866 |
0.629 |
|
| 1997 |
Stefani E, Ottolia M, Noceti F, Olcese R, Wallner M, Latorre R, Toro L. Voltage-controlled gating in a large conductance Ca2+-sensitive K+channel (hslo). Proceedings of the National Academy of Sciences of the United States of America. 94: 5427-31. PMID 9144254 DOI: 10.1073/Pnas.94.10.5427 |
0.782 |
|
| 1997 |
Nobile M, Olcese R, Toro L, Stefani E. Fast inactivation of Shaker K+ channels is highly temperature dependent. Experimental Brain Research. 114: 138-42. PMID 9125459 DOI: 10.1007/Pl00005613 |
0.678 |
|
| 1997 |
Zhou J, Olcese R, Qin N, Noceti F, Birnbaumer L, Stefani E. Feedback inhibition of Ca2+ channels by Ca2+ depends on a short sequence of the C terminus that does not include the Ca2+ -binding function of a motif with similarity to Ca2+ -binding domains. Proceedings of the National Academy of Sciences of the United States of America. 94: 2301-5. PMID 9122189 DOI: 10.1073/Pnas.94.6.2301 |
0.552 |
|
| 1997 |
Tareilus E, Roux M, Qin N, Olcese R, Zhou J, Stefani E, Birnbaumer L. A Xenopus oocyte beta subunit: evidence for a role in the assembly/expression of voltage-gated calcium channels that is separate from its role as a regulatory subunit. Proceedings of the National Academy of Sciences of the United States of America. 94: 1703-8. PMID 9050842 DOI: 10.1073/Pnas.94.5.1703 |
0.603 |
|
| 1997 |
Olcese R, Ottolia M, Qin N, Platano D, Birnbaumer M, Toro L, Birnbaumer L, Stefani E. A641 STIMULATION OF THE MICRO OPIOID RECEPTOR INHIBITS THE ACTIVITY OF THE NEURONAL E-TYPE Ca sup 2+ CHANNEL Anesthesiology. 87: 641A. DOI: 10.1097/00000542-199709001-00641 |
0.674 |
|
| 1996 |
Wei X, Neely A, Olcese R, Lang W, Stefani E, Birnbaumer L. Increase in Ca2+ channel expression by deletions at the amino terminus of the cardiac alpha 1C subunit. Receptors & Channels. 4: 205-15. PMID 9065969 |
0.764 |
|
| 1996 |
Olcese R, Neely A, Qin N, Wei X, Birnbaumer L, Stefani E. Coupling between charge movement and pore opening in vertebrate neuronal alpha 1E calcium channels. The Journal of Physiology. 497: 675-86. PMID 9003553 DOI: 10.1113/Jphysiol.1996.Sp021799 |
0.738 |
|
| 1996 |
Qin N, Olcese R, Zhou J, Cabello OA, Birnbaumer L, Stefani E. Identification of a second region of the beta-subunit involved in regulation of calcium channel inactivation. The American Journal of Physiology. 271: C1539-45. PMID 8944637 DOI: 10.1152/Ajpcell.1996.271.5.C1539 |
0.639 |
|
| 1995 |
Neely A, Olcese R, Baldelli P, Wei X, Birnbaumer L, Stefani E. Dual activation of the cardiac Ca2+ channel alpha 1C-subunit and its modulation by the beta-subunit. The American Journal of Physiology. 268: C732-40. PMID 7900777 DOI: 10.1152/Ajpcell.1995.268.3.C732 |
0.796 |
|
| 1994 |
Olcese R, Usai C, Maestrone E, Nobile M. The general anesthetic propofol inhibits transmembrane calcium current in chick sensory neurons. Anesthesia and Analgesia. 78: 955-60. PMID 8160997 |
0.397 |
|
| 1994 |
Neely A, Olcese R, Wei X, Birnbaumer L, Stefani E. Ca(2+)-dependent inactivation of a cloned cardiac Ca2+ channel alpha 1 subunit (alpha 1C) expressed in Xenopus oocytes. Biophysical Journal. 66: 1895-903. PMID 8075326 DOI: 10.1016/S0006-3495(94)80983-X |
0.789 |
|
| 1994 |
Olcese R, Qin N, Schneider T, Neely A, Wei X, Stefani E, Birnbaumer L. The amino terminus of a calcium channel beta subunit sets rates of channel inactivation independently of the subunit's effect on activation. Neuron. 13: 1433-8. PMID 7993634 DOI: 10.1016/0896-6273(94)90428-6 |
0.706 |
|
| 1994 |
Schneider T, Wei X, Olcese R, Costantin JL, Neely A, Palade P, Perez-Reyes E, Qin N, Zhou J, Crawford GD. Molecular analysis and functional expression of the human type E neuronal Ca2+ channel alpha 1 subunit. Receptors & Channels. 2: 255-70. PMID 7536609 |
0.699 |
|
| 1994 |
Wei X, Neely A, Lacerda AE, Olcese R, Stefani E, Perez-Reyes E, Birnbaumer L. Modification of Ca2+ channel activity by deletions at the carboxyl terminus of the cardiac alpha 1 subunit. The Journal of Biological Chemistry. 269: 1635-40. PMID 7507480 |
0.791 |
|
| 1993 |
Neely A, Wei X, Olcese R, Birnbaumer L, Stefani E. Potentiation by the beta subunit of the ratio of the ionic current to the charge movement in the cardiac calcium channel. Science (New York, N.Y.). 262: 575-8. PMID 8211185 DOI: 10.1126/Science.8211185 |
0.785 |
|
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