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Voula Kanelis, Ph.D. - Publications

Affiliations: 
2001 University of Toronto, Toronto, ON, Canada 
Area:
Biochemistry
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32 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2021 Woloschuk RM, Reed PMM, Jaikaran ASI, Demmans KZ, Youn J, Kanelis V, Uppalapati M, Woolley GA. Structure-based design of a photoswitchable affibody scaffold. Protein Science : a Publication of the Protein Society. PMID 34590762 DOI: 10.1002/pro.4196  0.35
2021 Bickers SC, Benlekbir S, Rubinstein JL, Kanelis V. Structure of Ycf1p reveals the transmembrane domain TMD0 and the regulatory region of ABCC transporters. Proceedings of the National Academy of Sciences of the United States of America. 118. PMID 34021087 DOI: 10.1073/pnas.2025853118  0.406
2020 Weiditch SA, Bickers SC, Bona D, Maxwell KL, Kanelis V. HK97 gp74 possesses an α-helical insertion in the ββα fold that affects its metal binding, cos site digestion, and activities. Journal of Bacteriology. PMID 31988081 DOI: 10.1128/Jb.00644-19  0.398
2020 Bickers SC, Sayewich JS, Kanelis V. Intrinsically disordered regions regulate the activities of ATP binding cassette transporters. Biochimica Et Biophysica Acta. Biomembranes. 183202. PMID 31972165 DOI: 10.1016/J.Bbamem.2020.183202  0.486
2019 Weiditch SA, Seraphim TV, Houry WA, Kanelis V. Strategies for purification of the bacteriophage HK97 small and large terminase subunits that yield pure and homogeneous samples that are functional. Protein Expression and Purification. 160: 45-55. PMID 30954531 DOI: 10.1016/J.Pep.2019.03.017  0.303
2018 Sooklal CR, Lopez-Alonso JP, Papp N, Kanelis V. Phosphorylation alters the residual structure and interactions of the regulatory L1 linker connecting NBD1 to the membrane-bound domain in SUR2B. Biochemistry. PMID 30273482 DOI: 10.1021/Acs.Biochem.8B00503  0.469
2017 Zhao J, Beyrakhova K, Liu Y, Alvarez CP, Bueler SA, Xu L, Xu C, Boniecki MT, Kanelis V, Luo ZQ, Cygler M, Rubinstein JL. Molecular basis for the binding and modulation of V-ATPase by a bacterial effector protein. Plos Pathogens. 13: e1006394. PMID 28570695 DOI: 10.1371/Journal.Ppat.1006394  0.426
2017 Alvarez CP, Stagljar M, Muhandiram DR, Kanelis V. Hyperinsulinism-causing mutations cause multiple molecular defects in SUR1 NBD1. Biochemistry. PMID 28346775 DOI: 10.1021/Acs.Biochem.6B00681  0.494
2015 de Araujo ED, Alvarez CP, López-Alonso JP, Sooklal CR, Stagljar M, Kanelis V. Phosphorylation-dependent changes in nucleotide binding, conformation, and dynamics of the first nucleotide binding domain (NBD1) of the sulfonylurea receptor 2B (SUR2B). The Journal of Biological Chemistry. 290: 22699-714. PMID 26198630 DOI: 10.1074/Jbc.M114.636233  0.492
2014 de Araujo ED, Kanelis V. Successful development and use of a thermodynamic stability screen for optimizing the yield of nucleotide binding domains. Protein Expression and Purification. 103: 38-47. PMID 25153533 DOI: 10.1016/J.Pep.2014.08.006  0.477
2014 Kala S, Cumby N, Sadowski PD, Hyder BZ, Kanelis V, Davidson AR, Maxwell KL. HNH proteins are a widespread component of phage DNA packaging machines. Proceedings of the National Academy of Sciences of the United States of America. 111: 6022-7. PMID 24711378 DOI: 10.1073/Pnas.1320952111  0.311
2012 López-Alonso JP, de Araujo ED, Kanelis V. NMR and fluorescence studies of drug binding to the first nucleotide binding domain of SUR2A. Biochemistry. 51: 9211-22. PMID 23078514 DOI: 10.1021/Bi301019E  0.527
2012 Moodley S, Maxwell KL, Kanelis V. The protein gp74 from the bacteriophage HK97 functions as a HNH endonuclease. Protein Science : a Publication of the Protein Society. 21: 809-18. PMID 22434504 DOI: 10.1002/Pro.2064  0.361
2011 de Araujo ED, Ikeda LK, Tzvetkova S, Kanelis V. The first nucleotide binding domain of the sulfonylurea receptor 2A contains regulatory elements and is folded and functions as an independent module. Biochemistry. 50: 6655-66. PMID 21714514 DOI: 10.1021/Bi200434D  0.556
2011 Kanelis V, Chong PA, Forman-Kay JD. NMR spectroscopy to study the dynamics and interactions of CFTR. Methods in Molecular Biology (Clifton, N.J.). 741: 377-403. PMID 21594798 DOI: 10.1007/978-1-61779-117-8_25  0.464
2010 Pell LG, Gasmi-Seabrook GM, Morais M, Neudecker P, Kanelis V, Bona D, Donaldson LW, Edwards AM, Howell PL, Davidson AR, Maxwell KL. The solution structure of the C-terminal Ig-like domain of the bacteriophage λ tail tube protein. Journal of Molecular Biology. 403: 468-79. PMID 20826161 DOI: 10.1016/J.Jmb.2010.08.044  0.525
2010 Kanelis V, Hudson RP, Thibodeau PH, Thomas PJ, Forman-Kay JD. NMR evidence for differential phosphorylation-dependent interactions in WT and DeltaF508 CFTR. The Embo Journal. 29: 263-77. PMID 19927121 DOI: 10.1038/Emboj.2009.329  0.533
2009 Pell LG, Kanelis V, Donaldson LW, Howell PL, Davidson AR. The phage lambda major tail protein structure reveals a common evolution for long-tailed phages and the type VI bacterial secretion system. Proceedings of the National Academy of Sciences of the United States of America. 106: 4160-5. PMID 19251647 DOI: 10.1073/Pnas.0900044106  0.353
2008 Bruce MC, Kanelis V, Fouladkou F, Debonneville A, Staub O, Rotin D. Regulation of Nedd4-2 self-ubiquitination and stability by a PY motif located within its HECT-domain. The Biochemical Journal. 415: 155-63. PMID 18498246 DOI: 10.1042/Bj20071708  0.691
2007 Baker JM, Hudson RP, Kanelis V, Choy WY, Thibodeau PH, Thomas PJ, Forman-Kay JD. CFTR regulatory region interacts with NBD1 predominantly via multiple transient helices. Nature Structural & Molecular Biology. 14: 738-45. PMID 17660831 DOI: 10.1038/Nsmb1278  0.418
2007 Chitayat S, Kanelis V, Koschinsky ML, Smith SP. Nuclear magnetic resonance (NMR) solution structure, dynamics, and binding properties of the kringle IV type 8 module of apolipoprotein(a). Biochemistry. 46: 1732-42. PMID 17263558 DOI: 10.1021/Bi061814G  0.433
2007 Baker J, Hudson R, Kanelis V, Choy W, Thibodeau P, Thomas P, Forman-Kay J. 1H, 13C, and 15N Backbone Assignments and 13C Aliphatic Sidechain Assignments for PKA Phosphorylated CFTR Regulatory Region Journal of Back and Musculoskeletal Rehabilitation. DOI: 10.13018/Bmr15340  0.302
2006 Kanelis V, Bruce MC, Skrynnikov NR, Rotin D, Forman-Kay JD. Structural determinants for high-affinity binding in a Nedd4 WW3* domain-Comm PY motif complex. Structure (London, England : 1993). 14: 543-53. PMID 16531238 DOI: 10.1016/J.Str.2005.11.018  0.685
2003 Henry PC, Kanelis V, O'Brien MC, Kim B, Gautschi I, Forman-Kay J, Schild L, Rotin D. Affinity and specificity of interactions between Nedd4 isoforms and the epithelial Na+ channel. The Journal of Biological Chemistry. 278: 20019-28. PMID 12654927 DOI: 10.1074/Jbc.M211153200  0.731
2002 Kanelis V, Forman-Kay JD, Kay LE. Multidimensional NMR methods for protein structure determination Iubmb Life. 52: 291-302. PMID 11895078 DOI: 10.1080/152165401317291147  0.313
2001 Rotin D, Kanelis V, Schild L. Trafficking and cell surface stability of ENaC. American Journal of Physiology. Renal Physiology. 281: F391-9. PMID 11502587 DOI: 10.1152/Ajprenal.2001.281.3.F391  0.578
2001 Kanelis V, Rotin D, Forman-Kay JD. Solution structure of a Nedd4 WW domain-ENaC peptide complex. Nature Structural Biology. 8: 407-12. PMID 11323714 DOI: 10.1038/87562  0.719
2001 Kanelis V, Rotin D, Forman-Kay J. Chemical Shift Assignments and Coupling Constants for the rat Nedd4 WWIII domain - rat ENaC bP2 Peptide Complex Journal of Back and Musculoskeletal Rehabilitation. DOI: 10.13018/Bmr4963  0.575
2000 Kanelis V, Donaldson L, Muhandiram DR, Rotin D, Forman-Kay JD, Kay LE. Sequential assignment of proline-rich regions in proteins: application to modular binding domain complexes. Journal of Biomolecular Nmr. 16: 253-9. PMID 10805132 DOI: 10.1023/A:1008355012528  0.649
2000 Staub O, Abriel H, Plant P, Ishikawa T, Kanelis V, Saleki R, Horisberger JD, Schild L, Rotin D. Regulation of the epithelial Na+ channel by Nedd4 and ubiquitination. Kidney International. 57: 809-15. PMID 10720933 DOI: 10.1046/J.1523-1755.2000.00919.X  0.718
1998 Kanelis V, Farrow NA, Kay LE, Rotin D, Forman-Kay JD. NMR studies of tandem WW domains of Nedd4 in complex with a PY motif-containing region of the epithelial sodium channel. Biochemistry and Cell Biology = Biochimie Et Biologie Cellulaire. 76: 341-50. PMID 9923703 DOI: 10.1139/Bcb-76-2-3-341  0.677
1998 Kanelis V, Farrow NA, Kay LE, Rotin D, Forman-Kay JD. NMR studies of tandem WW domains of Nedd4 in complex with a PY motif-containing region of the epithelial sodium channel Biochemistry and Cell Biology. 76: 341-350. DOI: 10.1139/o98-042  0.508
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