| Year |
Citation |
Score |
| 2021 |
Navarro S, Quintana-Bustamante O, Sanchez-Dominguez R, Lopez-Manzaneda S, Ojeda-Perez I, Garcia-Torralba A, Alberquilla O, Law K, Beard BC, Bastone A, Rothe M, Villanueva M, Ramirez JC, Fañanas-Baquero S, Nieto-Romero V, et al. Preclinical studies of efficacy thresholds and tolerability of a clinically ready lentiviral vector for pyruvate kinase deficiency treatment. Molecular Therapy. Methods & Clinical Development. 22: 350-359. PMID 34514027 DOI: 10.1016/j.omtm.2021.07.006 |
0.42 |
|
| 2020 |
Czechowicz A, Rio P, Bueren JE, Beard B, Nicoletti E, Schwartz J, Soni S. Changing the Natural History of Fanconi Anemia Complementation Group-À with Gene Therapy: Early Results of U.S. Phase I Study of Lentiviral-Mediated Ex-Vivo FANCA Gene Insertion in Human Stem and Progenitor Cells Biology of Blood and Marrow Transplantation. 26. DOI: 10.1016/J.Bbmt.2019.12.106 |
0.476 |
|
| 2019 |
Czechowicz A, Roncarolo MG, Beard BC, Law K, Nicoletti E, Río P, Bueren JA, Schwartz JD, Soni S. Changing the Natural History of Fanconi Anemia Complementation Group-A with Gene Therapy: Early Results of U.S. Phase I Study of Lentiviral-Mediated Ex-VivoFANCA Gene Insertion in Human Stem and Progenitor Cells Blood. 134: 3350-3350. DOI: 10.1182/Blood-2019-127352 |
0.434 |
|
| 2019 |
Almarza E, Mesa-Núñez C, Damián C, Fernández-García M, Díez-Cabezas B, Lozano ML, Rio P, Yañez RM, Law K, Beard BC, Schwartz JD, Bueren JA. Gene Therapy for Lad-I Immunodeficiency: Preclinical Evaluation of HSC Transduction Under Optimized GMP-Conditions Blood. 134: 5751-5751. DOI: 10.1182/Blood-2019-122878 |
0.341 |
|
| 2018 |
Haworth KG, Ironside C, Ramirez MA, Weitz S, Beard BC, Schwartz J, Adair JE, Kiem HP. Minimal conditioning in Fanconi anemia promotes multi-lineage marrow engraftment at ten-fold lower cell doses. The Journal of Gene Medicine. e3050. PMID 30129972 DOI: 10.1002/Jgm.3050 |
0.496 |
|
| 2016 |
Ruan H, Qiu S, Beard BC, Black ME. Creation of zebularine-resistant human cytidine deaminase mutants to enhance the chemoprotection of hematopoietic stem cells. Protein Engineering, Design & Selection : Peds. PMID 27160178 DOI: 10.1093/Protein/Gzw012 |
0.437 |
|
| 2015 |
Burtner CR, Chandrasekaran D, Santos EB, Beard BC, Adair JE, Hamlin DK, Wilbur DS, Sandmaier BM, Kiem HP. (211)Astatine-Conjugated Monoclonal CD45 Antibody-Based Nonmyeloablative Conditioning for Stem Cell Gene Therapy. Human Gene Therapy. 26: 399-406. PMID 25919226 DOI: 10.1089/Hum.2015.021 |
0.447 |
|
| 2014 |
Kiem HP, Arumugam PI, Burtner CR, Fox CF, Beard BC, Dexheimer P, Adair JE, Malik P. Pigtailed macaques as a model to study long-term safety of lentivirus vector-mediated gene therapy for hemoglobinopathies. Molecular Therapy. Methods & Clinical Development. 1: 14055. PMID 26052523 DOI: 10.1038/Mtm.2014.55 |
0.464 |
|
| 2014 |
Adair JE, Johnston SK, Mrugala MM, Beard BC, Guyman LA, Baldock AL, Bridge CA, Hawkins-Daarud A, Gori JL, Born DE, Gonzalez-Cuyar LF, Silbergeld DL, Rockne RC, Storer BE, Rockhill JK, et al. Gene therapy enhances chemotherapy tolerance and efficacy in glioblastoma patients. The Journal of Clinical Investigation. 124: 4082-92. PMID 25105369 DOI: 10.1172/Jci76739 |
0.395 |
|
| 2014 |
Beard BC, Adair JE, Trobridge GD, Kiem HP. High-throughput genomic mapping of vector integration sites in gene therapy studies. Methods in Molecular Biology (Clifton, N.J.). 1185: 321-44. PMID 25062639 DOI: 10.1007/978-1-4939-1133-2_22 |
0.407 |
|
| 2014 |
Watts KL, Beard BC, Wood BL, Trobridge GD, Humphries RK, Adams AB, Nelson V, Kiem HP. No evidence of clonal dominance after transplant of HOXB4-expanded cord blood cells in a nonhuman primate model. Experimental Hematology. 42: 497-504. PMID 24704161 DOI: 10.1016/J.Exphem.2014.03.007 |
0.428 |
|
| 2014 |
Burtner CR, Beard BC, Kennedy DR, Wohlfahrt ME, Adair JE, Trobridge GD, Scharenberg AM, Torgerson TR, Rawlings DJ, Felsburg PJ, Kiem HP. Intravenous injection of a foamy virus vector to correct canine SCID-X1. Blood. 123: 3578-84. PMID 24642749 DOI: 10.1182/Blood-2013-11-538926 |
0.466 |
|
| 2014 |
Wurm M, Kowalski J, Heckl D, Zhang XB, Nelson V, Beard BC, Kiem HP. Ectopic expression of HOXC6 blocks myeloid differentiation and predisposes to malignant transformation. Experimental Hematology. 42: 114-25.e4. PMID 24513167 DOI: 10.1016/J.Exphem.2013.10.004 |
0.467 |
|
| 2014 |
Mrugala MM, Adair JE, Beard BC, Silbergeld DL, Halasz L, Rockhill JK, Kiem H. P17.59Transplanted Mgmtp140K Gene-Modified Cd34+ Cells In Patients With Newly Diagnosed Glioblastoma Chemo-Protect Bone Marrow And Lead To Prolonged Survival. Neuro-Oncology. 16. DOI: 10.1093/Neuonc/Nou174.388 |
0.456 |
|
| 2013 |
Watts KL, Delaney C, Nelson V, Trobridge GD, Beard BC, Humphries RK, Kiem HP. CD34(+) Expansion With Delta-1 and HOXB4 Promotes Rapid Engraftment and Transfusion Independence in a Macaca nemestrina Cord Blood Transplant Model. Molecular Therapy : the Journal of the American Society of Gene Therapy. 21: 1270-1278. PMID 28160801 DOI: 10.1038/mt.2013.40 |
0.328 |
|
| 2013 |
Younan PM, Polacino P, Kowalski JP, Peterson CW, Maurice NJ, Williams NP, Ho O, Trobridge GD, Von Laer D, Prlic M, Beard BC, DeRosa S, Hu SL, Kiem HP. Positive selection of mC46-expressing CD4+ T cells and maintenance of virus specific immunity in a primate AIDS model. Blood. 122: 179-87. PMID 23719296 DOI: 10.1182/Blood-2013-01-482224 |
0.434 |
|
| 2013 |
Gori JL, Beard BC, Williams NP, Ironside C, Swanson D, Scott McIvor R, Kiem HP. In vivo protection of activated Tyr22-dihydrofolate reductase gene-modified canine T lymphocytes from methotrexate. The Journal of Gene Medicine. 15: 233-41. PMID 23666780 DOI: 10.1002/Jgm.2713 |
0.427 |
|
| 2013 |
Watts KL, Delaney C, Nelson V, Trobridge GD, Beard BC, Humphries RK, Kiem HP. CD34(+) expansion with Delta-1 and HOXB4 promotes rapid engraftment and transfusion independence in a Macaca nemestrina cord blood transplant model. Molecular Therapy : the Journal of the American Society of Gene Therapy. 21: 1270-8. PMID 23587923 DOI: 10.1038/Mt.2013.40 |
0.43 |
|
| 2013 |
Berger C, Berger M, Beard BC, Kiem HP, Gooley TA, Riddell SR. Proliferation-linked apoptosis of adoptively transferred T cells after IL-15 administration in macaques. Plos One. 8: e56268. PMID 23418547 DOI: 10.1371/Journal.Pone.0056268 |
0.339 |
|
| 2013 |
Trobridge GD, Beard BC, Wu RA, Ironside C, Malik P, Kiem H. Correction: Stem Cell Selection In Vivo Using Foamy Vectors Cures Canine Pyruvate Kinase Deficiency Plos One. 8. DOI: 10.1371/Annotation/90F278B2-F474-42Ec-8645-435F7006018C |
0.387 |
|
| 2013 |
Johnston SK, Adair JE, Bridge C, Guyman L, Hawkins-Daarud A, Rockne R, Baldock A, Rockhill JK, Mrugala MM, Beard BC, Kiem H, Swanson K. Patient-specific mathematical modeling as a precision-medicine approach to evaluating therapeutic gains of a novel chemoprotection treatment in newly diagnosed glioblastoma. Journal of Clinical Oncology. 31. DOI: 10.1200/Jco.2013.31.15_Suppl.E13041 |
0.383 |
|
| 2013 |
Gori JL, Butler JM, Chandrasekaran D, Beard BC, Nolan DJ, Ginsberg M, Adair JE, Rafii S, Kiem H. In Vivo Selection and Long-Term Engraftment Of Hematopoietic Stem Cells Generated Via Vascular Niche Induction Of Nonhuman Primate Induced Pluripotent Stem Cells Blood. 122: 466-466. DOI: 10.1182/Blood.V122.21.466.466 |
0.432 |
|
| 2013 |
Kiem H, Arumugam P, Christopher B, Adair JE, Beard BC, Fox C, Malik P. Safety Of a Gamma Globin Expressing Lentivirus Vector In a Non-Human Primate Model For Gene Therapy Of Sickle Cell Disease Blood. 122: 2896-2896. DOI: 10.1182/Blood.V122.21.2896.2896 |
0.49 |
|
| 2012 |
Trobridge GD, Horn PA, Beard BC, Kiem HP. Large animal models for foamy virus vector gene therapy. Viruses. 4: 3572-88. PMID 23223198 DOI: 10.3390/V4123572 |
0.507 |
|
| 2012 |
Trobridge GD, Beard BC, Wu RA, Ironside C, Malik P, Kiem HP. Stem cell selection in vivo using foamy vectors cures canine pyruvate kinase deficiency. Plos One. 7: e45173. PMID 23028826 DOI: 10.1371/Journal.Pone.0045173 |
0.494 |
|
| 2012 |
Gori JL, Chandrasekaran D, Kowalski JP, Adair JE, Beard BC, D'Souza SL, Kiem HP. Efficient generation, purification, and expansion of CD34(+) hematopoietic progenitor cells from nonhuman primate-induced pluripotent stem cells. Blood. 120: e35-44. PMID 22898598 DOI: 10.1182/Blood-2012-05-433797 |
0.417 |
|
| 2012 |
Adair JE, Zhao X, Chien S, Fang M, Wohlfahrt ME, Trobridge GD, Taylor JA, Beard BC, Kiem HP, Becker PS. Cyclophosphamide promotes engraftment of gene-modified cells in a mouse model of Fanconi anemia without causing cytogenetic abnormalities. Journal of Molecular Medicine (Berlin, Germany). 90: 1283-94. PMID 22660274 DOI: 10.1007/S00109-012-0905-0 |
0.493 |
|
| 2012 |
Gori JL, Beard BC, Ironside C, Karponi G, Kiem HP. In vivo selection of autologous MGMT gene-modified cells following reduced-intensity conditioning with BCNU and temozolomide in the dog model Cancer Gene Therapy. 19: 523-529. PMID 22627392 DOI: 10.1038/Cgt.2012.25 |
0.532 |
|
| 2012 |
Adair JE, Beard BC, Trobridge GD, Neff T, Rockhill JK, Silbergeld DL, Mrugala MM, Kiem HP. Extended survival of glioblastoma patients after chemoprotective HSC gene therapy. Science Translational Medicine. 4: 133ra57. PMID 22572881 DOI: 10.1126/Scitranslmed.3003425 |
0.493 |
|
| 2012 |
Watts KL, Nelson V, Wood BL, Trobridge GD, Beard BC, Humphries RK, Kiem HP. Hematopoietic stem cell expansion facilitates multilineage engraftment in a nonhuman primate cord blood transplantation model. Experimental Hematology. 40: 187-96. PMID 22155723 DOI: 10.1016/J.Exphem.2011.11.009 |
0.441 |
|
| 2012 |
Muñoz NM, Beard BC, Ryu BY, Luche RM, Trobridge GD, Rawlings DJ, Scharenberg AM, Kiem HP. Novel reporter systems for facile evaluation of I-SceI-mediated genome editing. Nucleic Acids Research. 40: e14. PMID 22110042 DOI: 10.1093/Nar/Gkr897 |
0.417 |
|
| 2011 |
Okazuka K, Beard BC, Emery DW, Schwarzwaelder K, Spector MR, Sale GE, von Kalle C, Torok-Storb B, Kiem HP, Blau CA. Corrigendum to "Long-term Regulation of Genetically Modified Primary Hematopoietic Cells in Dogs". Molecular Therapy : the Journal of the American Society of Gene Therapy. 19: 2102. PMID 28160652 DOI: 10.1038/Mt.2011.180 |
0.332 |
|
| 2011 |
Watts KL, Zhang X, Beard BC, Chiu SY, Trobridge GD, Humphries RK, Kiem HP. Differential effects of HOXB4 and NUP98-HOXA10hd on hematopoietic repopulating cells in a nonhuman primate model. Human Gene Therapy. 22: 1475-82. PMID 21787196 DOI: 10.1089/Hum.2011.100 |
0.468 |
|
| 2011 |
Okazuka K, Beard BC, Emery DW, Schwarzwaelder K, Spector MR, Sale GE, von Kalle C, Torok-Storb B, Kiem HP, Blau CA. Long-term regulation of genetically modified primary hematopoietic cells in dogs. Molecular Therapy : the Journal of the American Society of Gene Therapy. 19: 1287-94. PMID 21326218 DOI: 10.1038/Mt.2011.8 |
0.392 |
|
| 2011 |
Adair JE, Beard BC, Trobridge G, Bushman F, Mrugala MM, Kiem H. Integration-Mediated Activation of PRDM16 and HMGA2 in Multiple Clones without Adverse Hematopoietic Consequences Following Transplant of Autologous MGMTP140K Gene-Modified CD34+ Cells Blood. 118: 2053-2053. DOI: 10.1182/Blood.V118.21.2053.2053 |
0.508 |
|
| 2011 |
Wurm M, Williams N, Ironside C, Beard BC, Kiem H. Drug Resistance Gene Therapy to Augment Allogeneic Transplantation for the Treatment of Leukemia Following Relapse Blood. 118: 2050-2050. DOI: 10.1182/Blood.V118.21.2050.2050 |
0.477 |
|
| 2010 |
Beard BC, Trobridge GD, Ironside C, McCune JS, Adair JE, Kiem HP. Efficient and stable MGMT-mediated selection of long-term repopulating stem cells in nonhuman primates. The Journal of Clinical Investigation. 120: 2345-54. PMID 20551514 DOI: 10.1172/Jci40767 |
0.484 |
|
| 2010 |
Becker PS, Taylor JA, Trobridge GD, Zhao X, Beard BC, Chien S, Adair J, Kohn DB, Wagner JE, Shimamura A, Kiem HP. Preclinical correction of human Fanconi anemia complementation group A bone marrow cells using a safety-modified lentiviral vector. Gene Therapy. 17: 1244-52. PMID 20485382 DOI: 10.1038/Gt.2010.62 |
0.475 |
|
| 2010 |
Kiem HP, Ironside C, Beard BC, Trobridge GD. A retroviral vector common integration site between leupaxin and zinc finger protein 91 (ZFP91) observed in baboon hematopoietic repopulating cells. Experimental Hematology. 38: 819-22, 822.e1-3. PMID 20434516 DOI: 10.1016/J.Exphem.2010.04.014 |
0.456 |
|
| 2010 |
Trobridge GD, Wu RA, Hansen M, Ironside C, Watts KL, Olsen P, Beard BC, Kiem HP. Cocal-pseudotyped lentiviral vectors resist inactivation by human serum and efficiently transduce primate hematopoietic repopulating cells. Molecular Therapy : the Journal of the American Society of Gene Therapy. 18: 725-33. PMID 19997089 DOI: 10.1038/Mt.2009.282 |
0.46 |
|
| 2010 |
Enssle J, Trobridge GD, Keyser KA, Ironside C, Beard BC, Kiem HP. Stable marking and transgene expression without progression to monoclonality in canine long-term hematopoietic repopulating cells transduced with lentiviral vectors. Human Gene Therapy. 21: 397-403. PMID 19947827 DOI: 10.1089/Hum.2009.076 |
0.466 |
|
| 2010 |
Becker PS, Adair J, Zhao X, Chien S, Wohlfahrt ME, Trobridge G, Beard BC, Kiem H. Towards Defining An Optimal Conditioning Regimen for Stem Cell Gene Therapy In Fanconi Anemia. Blood. 116: 1478-1478. DOI: 10.1182/Blood.V116.21.1478.1478 |
0.406 |
|
| 2009 |
Trobridge GD, Wu RA, Beard BC, Chiu SY, Muñoz NM, von Laer D, Rossi JJ, Kiem HP. Protection of stem cell-derived lymphocytes in a primate AIDS gene therapy model after in vivo selection. Plos One. 4: e7693. PMID 19888329 DOI: 10.1371/Journal.Pone.0007693 |
0.494 |
|
| 2009 |
Thakar MS, Zhang XB, Beard BC, Sale GE, Santos EB, Peterson L, Kiem HP, Sandmaier BM. Transmission and expansion of HOXB4-induced leukemia in two immunosuppressed dogs: implications for a new canine leukemia model. Experimental Hematology. 37: 1157-66. PMID 19616601 DOI: 10.1016/J.Exphem.2009.07.004 |
0.425 |
|
| 2009 |
Beard BC, Sud R, Keyser KA, Ironside C, Neff T, Gerull S, Trobridge GD, Kiem HP. Long-term polyclonal and multilineage engraftment of methylguanine methyltransferase P140K gene-modified dog hematopoietic cells in primary and secondary recipients. Blood. 113: 5094-103. PMID 19336761 DOI: 10.1182/Blood-2008-09-176412 |
0.525 |
|
| 2009 |
Beard BC, Kiem HP. Canine models of gene-modified hematopoiesis. Methods in Molecular Biology (Clifton, N.J.). 506: 341-61. PMID 19110637 DOI: 10.1007/978-1-59745-409-4_23 |
0.415 |
|
| 2009 |
Beard BC, Trobridge GD, McCune JS, Kiem H. Efficient MGMTP140K-Mediated In Vivo Selection and Chemoprotection of Long-Term Repopulating Cells in Nonhuman Primates Following Reduced Intensity Conditioning. Blood. 114: 3572-3572. DOI: 10.1182/Blood.V114.22.3572.3572 |
0.511 |
|
| 2008 |
Mezquita P, Beard BC, Kiem HP. NOD/SCID repopulating cells contribute only to short-term repopulation in the baboon Gene Therapy. 15: 1460-1462. PMID 18563183 DOI: 10.1182/Blood.V106.11.1711.1711 |
0.441 |
|
| 2008 |
Trobridge GD, Beard BC, Gooch C, Wohlfahrt M, Olsen P, Fletcher J, Malik P, Kiem HP. Efficient transduction of pigtailed macaque hematopoietic repopulating cells with HIV-based lentiviral vectors. Blood. 111: 5537-43. PMID 18388180 DOI: 10.1182/Blood-2007-09-115022 |
0.486 |
|
| 2008 |
Zhang XB, Beard BC, Trobridge GD, Wood BL, Sale GE, Sud R, Humphries RK, Kiem HP. High incidence of leukemia in large animals after stem cell gene therapy with a HOXB4-expressing retroviral vector. The Journal of Clinical Investigation. 118: 1502-10. PMID 18357342 DOI: 10.1172/Jci34371 |
0.52 |
|
| 2008 |
Piasecki JC, Beagles K, Beard BC, Riddell S, Kiem HP. Induction of transgene-specific cytotoxic T lymphocyte responses after transplantation of gene-modified CD34+ cells despite nonablative immunosuppressive conditioning. Human Gene Therapy. 19: 103-7. PMID 18092920 DOI: 10.1089/Hum.2007.086 |
0.46 |
|
| 2008 |
Beard BC, Welsh ML, Trobridge GD, Kiem H. Efficient Gene Marking with a Clinical Gammaretrovirus Vector Expressing MGMTP140K in Baboons and Macaques Blood. 112: 3535-3535. DOI: 10.1182/Blood.V112.11.3535.3535 |
0.523 |
|
| 2007 |
Wohlfahrt ME, Beard BC, Lieber A, Kiem HP. A capsid-modified, conditionally replicating oncolytic adenovirus vector expressing TRAIL Leads to enhanced cancer cell killing in human glioblastoma models. Cancer Research. 67: 8783-90. PMID 17875719 DOI: 10.1158/0008-5472.Can-07-0357 |
0.323 |
|
| 2007 |
Jung CW, Beard BC, Morris JC, Neff T, Beebe K, Storer BE, Kiem HP. Hematopoietic stem cell engraftment: a direct comparison between intramarrow and intravenous injection in nonhuman primates. Experimental Hematology. 35: 1132-9. PMID 17588482 DOI: 10.1016/J.Exphem.2007.04.004 |
0.425 |
|
| 2007 |
Gerull S, Beard BC, Peterson LJ, Neff T, Kiem HP. In vivo selection and chemoprotection after drug resistance gene therapy in a nonmyeloablative allogeneic transplantation setting in dogs. Human Gene Therapy. 18: 451-6. PMID 17536975 DOI: 10.1089/Hum.2006.039 |
0.484 |
|
| 2007 |
Beard BC, Keyser KA, Trobridge GD, Peterson LJ, Miller DG, Jacobs M, Kaul R, Kiem HP. Unique integration profiles in a canine model of long-term repopulating cells transduced with gammaretrovirus, lentivirus, or foamy virus. Human Gene Therapy. 18: 423-34. PMID 17518616 DOI: 10.1089/Hum.2007.011 |
0.448 |
|
| 2007 |
Beard BC, Dickerson D, Beebe K, Gooch C, Fletcher J, Okbinoglu T, Miller DG, Jacobs MA, Kaul R, Kiem HP, Trobridge GD. Comparison of HIV-derived lentiviral and MLV-based gammaretroviral vector integration sites in primate repopulating cells. Molecular Therapy : the Journal of the American Society of Gene Therapy. 15: 1356-65. PMID 17440443 DOI: 10.1038/Sj.Mt.6300159 |
0.471 |
|
| 2006 |
Zhang XB, Beard BC, Beebe K, Storer B, Humphries RK, Kiem HP. Differential effects of HOXB4 on nonhuman primate short- and long-term repopulating cells. Plos Medicine. 3: e173. PMID 16637742 DOI: 10.1371/Journal.Pmed.0030173 |
0.484 |
|
| 2006 |
Beard BC, Mezquita P, Morris JC, Kiem HP. Efficient transduction and engraftment of G-CSF-mobilized peripheral blood CD34+ cells in nonhuman primates using GALV-pseudotyped gammaretroviral vectors. Molecular Therapy : the Journal of the American Society of Gene Therapy. 14: 212-7. PMID 16631413 DOI: 10.1016/J.Ymthe.2006.01.016 |
0.451 |
|
| 2006 |
Neff T, Beard BC, Kiem HP. Survival of the fittest: in vivo selection and stem cell gene therapy. Blood. 107: 1751-60. PMID 16269617 DOI: 10.1182/blood-2005-06-2335 |
0.419 |
|
| 2006 |
Trobridge GD, Beard BC, Dickerson D, Gooch C, Olsen P, Fletcher J, Li M, Hu S, Rossi JJ, Kiem H. Transduction of Macaque Hematopoietic Repopulating Cells with Lenti and Foamy Retroviral Vectors with MGMT Selection Cassettes To Evaluate AIDS Gene Therapy Strategies. Blood. 108: 3273-3273. DOI: 10.1182/Blood.V108.11.3273.3273 |
0.48 |
|
| 2006 |
Beard BC, Beebe K, Piasecki J, Gooch C, Dickerson D, Kiem H. MGMT (P140K) Allows for Efficient and Sustained In Vivo Selection in Non-Human Primates. Blood. 108: 3270-3270. DOI: 10.1182/Blood.V108.11.3270.3270 |
0.525 |
|
| 2006 |
Keyser KA, Beard BC, Trobridge G, Peterson LJ, Miller D, Jacobs M, Kaul R, Kiem H. Unique Integration Profiles of Gammaretrovirus, Lentivirus, and Foamy Virus Transduced Dog Long-Term Repopulating Cells. Blood. 108: 3252-3252. DOI: 10.1182/Blood.V108.11.3252.3252 |
0.439 |
|
| 2006 |
Beard BC, Sud R, Gerull S, Peterson LJ, Neff T, Kiem H. Sustained Stable Engraftment of MGMT Gene-Modified Long-Term Repopulating Cells in Primary and Secondary Canine Recipients. Blood. 108: 202-202. DOI: 10.1182/Blood.V108.11.202.202 |
0.498 |
|
| 2006 |
Beard BC, Gerull S, Peterson LJ, Neff T, Kiem H. 737. Efficient In Vivo Selection and Chemoprotection Following Drug Resistance Gene Therapy in a Nonmyeloablative Allogeneic Transplantation Setting in the Dog Molecular Therapy. 13. DOI: 10.1016/J.Ymthe.2006.08.818 |
0.54 |
|
| 2005 |
Trobridge G, Beard BC, Kiem HP. Hematopoietic stem cell transduction and amplification in large animal models. Human Gene Therapy. 16: 1355-66. PMID 16390267 DOI: 10.1089/Hum.2005.16.1355 |
0.522 |
|
| 2005 |
Beard BC, Stevenson JJ, Wilson SH, Smerdon MJ. Base excision repair in nucleosomes lacking histone tails. Dna Repair. 4: 203-9. PMID 15590328 DOI: 10.1016/J.Dnarep.2004.09.011 |
0.562 |
|
| 2005 |
Neff T, Beard BC, Peterson LJ, Anandakumar P, Thompson J, Kiem HP. Polyclonal chemoprotection against temozolomide in a large-animal model of drug resistance gene therapy. Blood. 105: 997-1002. PMID 15494421 DOI: 10.1182/Blood-2004-08-3169 |
0.454 |
|
| 2005 |
Trobridge GD, Beagles K, Beard B, Li M, Yee J, Rossi J, Hu S, Kiem H. A Non-Human Primate Model To Study Anti-HIV Gene Therapy Strategies. Blood. 106: 3046-3046. DOI: 10.1182/Blood.V106.11.3046.3046 |
0.437 |
|
| 2005 |
Beard BC, Mezquita P, Trobridge G, Peterson LJ, Neff T, Knapp AA, Kiem H. Genomic Mapping of Retrovirus Integration Profiles after In Vivo Selection of Chemo-Protected Stem Cells in the Clinically Relevant Canine Model. Blood. 106: 1293-1293. DOI: 10.1182/Blood.V106.11.1293.1293 |
0.491 |
|
| 2005 |
Zhang X, Peterson LJ, Knapp AA, Beard BC, Humphries RK, Kiem H. 456. HOXB4 Overexpression Expands Short-Term Repopulating Cells in Nonhuman Primates and Dogs Molecular Therapy. 11. DOI: 10.1016/J.Ymthe.2005.06.464 |
0.51 |
|
| 2005 |
Gerull S, Beagles KE, Beard BC, Peterson LJ, Kiem H. 455. Drug Resistance Gene Therapy to Induce Donor-Specific Tolerance after Nonmyeloablative Allogeneic Stem Cell Transplantation in Dogs Molecular Therapy. 11. DOI: 10.1016/J.Ymthe.2005.06.463 |
0.488 |
|
| 2005 |
Beagles K, Trobridge G, Beard B, Rossi J, Yee J, Hu S, KIem H. 440. A Non-Human Primate Model for Lentivirus-Mediated Anti-HIV RNAi Strategies Molecular Therapy. 11. DOI: 10.1016/J.Ymthe.2005.06.448 |
0.432 |
|
| 2005 |
Beard BC, Mezquita P, Morris JC, Kiem H. 5. Differential Expression of PIT1 and PIT2 after G-CSF Mobilization Is Associated with Efficient Gene Transfer Using GALV-Pseudotyped Gammaretroviral Vectors Molecular Therapy. 11. DOI: 10.1016/J.Ymthe.2005.06.008 |
0.423 |
|
| 2004 |
Beard BC, Smerdon MJ. Analysis of DNA repair on nucleosome templates. Methods in Enzymology. 377: 499-507. PMID 14979047 DOI: 10.1016/S0076-6879(03)77032-3 |
0.541 |
|
| 2004 |
Beagles K, Beard B, Rossi J, Yee J, Hu S, Trobridge G, Kiem H. A Non-Human Primate Model for Lentivirus-Mediated Anti-HIV RNAi Strategies. Blood. 104: 3103-3103. DOI: 10.1182/Blood.V104.11.3103.3103 |
0.423 |
|
| 2004 |
Beard BC, Mezquita P, Peterson LJ, Neff T, Anandakumar P, Knapp AA, Kiem H. Molecular Characterization of Stem Cell Populations and Specific Clone Tracking of Retrovirally-Marked Chemoprotected Stem Cells before and after Dose-Escalating Chemotherapy. Blood. 104: 291-291. DOI: 10.1182/Blood.V104.11.291.291 |
0.491 |
|
| 2004 |
Jung CW, Morris JC, Beard B, Neff T, Beebe K, Kiem H. Direct Intramarrow Injection of CD34+ Cells May Improve Long-Term Engraftment in Nonhuman Primates. Blood. 104: 2103-2103. DOI: 10.1182/Blood.V104.11.2103.2103 |
0.445 |
|
| 2004 |
Beard BC, Neff T, Peterson LJ, Thomasson B, Thompson J, Kiem H. 913. MGMT (P140K) allows for safe, efficient, and sustained in vivo selection and chemoprotection in a large animal model Molecular Therapy. 9. DOI: 10.1016/J.Ymthe.2004.06.819 |
0.501 |
|
| 2004 |
Beard BC, Keyser KA, Morris J, Thomasson B, Kiem H. 1. Molecular Long-Term Follow Up in Non-Human Primates That Received Retrovirally Transduced Stem Cells: Despite Proto-Oncogene Insertion No Leukemia or Hematopoietic Abnormalities Molecular Therapy. 9. DOI: 10.1016/J.Ymthe.2004.05.042 |
0.474 |
|
| 2003 |
Beard BC, Wilson SH, Smerdon MJ. Suppressed catalytic activity of base excision repair enzymes on rotationally positioned uracil in nucleosomes. Proceedings of the National Academy of Sciences of the United States of America. 100: 7465-70. PMID 12799467 DOI: 10.1073/Pnas.1330328100 |
0.569 |
|
| 2000 |
Conconi A, Jager-Vottero P, Zhang X, Beard BC, Smerdon MJ. Mitotic viability and metabolic competence in UV-irradiated yeast cells. Mutation Research. 459: 55-64. PMID 10677683 DOI: 10.1016/S0921-8777(99)00057-9 |
0.614 |
|
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