E. Michael Ostap - Publications

Affiliations: 
University of Pennsylvania School of Medicine, Philadelphia, PA, United States 

102 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2023 Pedersen RTA, Snoberger A, Pyrpassopoulos S, Safer D, Drubin DG, Ostap EM. Endocytic myosin-1 is a force-insensitive, power-generating motor. The Journal of Cell Biology. 222. PMID 37549220 DOI: 10.1083/jcb.202303095  0.355
2023 Báez-Cruz FA, Ostap EM. Drosophila class-I myosins that can impact left-right asymmetry have distinct ATPase kinetics. The Journal of Biological Chemistry. 299: 104961. PMID 37380077 DOI: 10.1016/j.jbc.2023.104961  0.417
2023 Pedersen RT, Snoberger A, Pyrpassopoulos S, Safer D, Drubin DG, Ostap EM. An endocytic myosin essential for plasma membrane invagination powers motility against resistance. Biorxiv : the Preprint Server For Biology. PMID 36993306 DOI: 10.1101/2023.03.21.533689  0.346
2023 Pollard LW, Coscia SM, Rebowski G, Palmer NJ, Holzbaur ELF, Dominguez R, Ostap EM. Ensembles of human myosin-19 bound to calmodulin and regulatory light chain RLC12B drive multimicron transport. The Journal of Biological Chemistry. 299: 102906. PMID 36642185 DOI: 10.1016/j.jbc.2023.102906  0.387
2022 Pyrpassopoulos S, Shuman H, Ostap EM. Microtubule Dumbbells to Assess the Effect of Force Geometry on Single Kinesin Motors. Methods in Molecular Biology (Clifton, N.J.). 2478: 559-583. PMID 36063334 DOI: 10.1007/978-1-0716-2229-2_20  0.322
2020 Bensel BM, Woody MS, Pyrpassopoulos S, Goldman YE, Gilbert SP, Ostap EM. The mechanochemistry of the kinesin-2 KIF3AC heterodimer is related to strain-dependent kinetic properties of KIF3A and KIF3C. Proceedings of the National Academy of Sciences of the United States of America. PMID 32571914 DOI: 10.1073/Pnas.1916343117  0.407
2020 Pyrpassopoulos S, Shuman H, Ostap EM. Modulation of Kinesin's Load-Bearing Capacity by Force Geometry and the Microtubule Track. Biophysical Journal. 118: 243-253. PMID 31883614 DOI: 10.1016/J.Bpj.2019.10.045  0.412
2019 Ji HH, Ostap EM. The regulatory protein 14-3-3β binds to the IQ motifs of myosin-IC independently of phosphorylation. The Journal of Biological Chemistry. PMID 31811090 DOI: 10.1074/Jbc.Ra119.011227  0.357
2019 Woody MS, Winkelmann DA, Capitanio M, Ostap EM, Goldman YE. Single molecule mechanics resolves the earliest events in force generation by cardiac myosin. Elife. 8. PMID 31526481 DOI: 10.7554/Elife.49266  0.374
2019 Welburn JPI, Ostap EM. Motors in transport and cytoskeleton remodeling. Molecular Biology of the Cell. 30: 734. PMID 30870091 DOI: 10.1091/Mbc.E19-01-0011  0.309
2019 Lebreton G, Géminard C, Lapraz F, Pyrpassopoulos S, Cerezo D, Spéder P, Ostap EM, Noselli S. Molecular to organismal chirality is induced by the conserved myosin 1D. Science (New York, N.Y.). 362: 949-952. PMID 30467170 DOI: 10.1126/science.aat8642  0.315
2019 Woody MS, Winkelmann DA, Capitanio M, Ostap EM, Goldman YE. Author response: Single molecule mechanics resolves the earliest events in force generation by cardiac myosin Elife. DOI: 10.7554/Elife.49266.025  0.34
2018 De La Cruz EM, Blanchoin L, Ostap EM. Opening remarks from the Editors. Biophysical Reviews. 10: 1479-1480. PMID 30488377 DOI: 10.1007/S12551-018-0487-3  0.522
2018 Woody MS, Greenberg MJ, Barua B, Winkelmann DA, Goldman YE, Ostap EM. Positive cardiac inotrope omecamtiv mecarbil activates muscle despite suppressing the myosin working stroke. Nature Communications. 9: 3838. PMID 30242219 DOI: 10.1038/S41467-018-06193-2  0.37
2018 Woody MS, Capitanio M, Ostap EM, Goldman YE. Electro-optic deflectors deliver advantages over acousto-optical deflectors in a high resolution, ultra-fast force-clamp optical trap. Optics Express. 26: 11181-11193. PMID 29716042 DOI: 10.1364/Oe.26.011181  0.347
2018 Mentes A, Huehn A, Liu X, Zwolak A, Dominguez R, Shuman H, Ostap EM, Sindelar CV. High-resolution cryo-EM structures of actin-bound myosin states reveal the mechanism of myosin force sensing. Proceedings of the National Academy of Sciences of the United States of America. PMID 29358376 DOI: 10.1016/J.Bpj.2017.11.1796  0.49
2018 McIntosh BB, Pyrpassopoulos S, Holzbaur ELF, Ostap EM. Opposing Kinesin and Myosin-I Motors Drive Membrane Deformation and Tubulation along Engineered Cytoskeletal Networks. Current Biology : Cb. PMID 29337076 DOI: 10.1016/J.Cub.2017.12.007  0.449
2018 Mentes A, Huehn A, Liu X, Zwolak A, Dominguez R, Shuman H, Ostap EM, Sindelar CV. High Resolution Cryo-EM Structures of Actin-Bound Myosin States Reveal the Mechanism of Myosin Force Sensing Biophysical Journal. 114: 319a. DOI: 10.1016/j.bpj.2017.11.1796  0.334
2018 Woody MS, Greenberg MJ, Barua B, Winkelmann DA, Goldman YE, Ostap EM. Single Molecule, Optical Trapping Studies of Omecamtiv Mercarbil on Human Cardiac Myosin's Force Production Biophysical Journal. 114: 317a-318a. DOI: 10.1016/J.Bpj.2017.11.1787  0.314
2017 Pyrpassopoulos S, Shuman H, Ostap EM. Adhesion force and attachment lifetime of the KIF16B-PX domain interaction with lipid membranes. Molecular Biology of the Cell. PMID 28931594 DOI: 10.1091/Mbc.E17-05-0324  0.413
2017 Greenberg MJ, Shuman H, Ostap EM. Measuring the Kinetic and Mechanical Properties of Non-processive Myosins Using Optical Tweezers. Methods in Molecular Biology (Clifton, N.J.). 1486: 483-509. PMID 27844441 DOI: 10.1007/978-1-4939-6421-5_19  0.448
2017 Pyrpassopoulos S, Shuman H, Ostap EM. A Comparative Single-Molecule Study Between the Mechanical Stability of Kinesin KIF16B Attachment to Lipid Membranes and to Microtubules Biophysical Journal. 112: 427a. DOI: 10.1016/J.Bpj.2016.11.2281  0.369
2017 McIntosh BB, Holzbaur EL, Ostap EM. Myo1C and Endophilin Promote Kinesin-Driven Tubulation at Engineered Cytoskeletal Intersections Biophysical Journal. 112: 273a. DOI: 10.1016/J.Bpj.2016.11.1480  0.444
2017 Ostap EM. Molecular Characterization of a Membrane-Associated Cytoskeletal Motor Family Biophysical Journal. 112: 10a-11a. DOI: 10.1016/J.Bpj.2016.11.086  0.447
2016 Ghiretti AE, Thies E, Tokito MK, Lin T, Ostap EM, Kneussel M, Holzbaur EL. Activity-Dependent Regulation of Distinct Transport and Cytoskeletal Remodeling Functions of the Dendritic Kinesin KIF21B. Neuron. PMID 27817978 DOI: 10.1016/J.Neuron.2016.10.003  0.367
2016 McIntosh BB, Ostap EM. Myosin-I molecular motors at a glance. Journal of Cell Science. PMID 27401928 DOI: 10.1242/Jcs.186403  0.423
2016 Greenberg MJ, Arpağ G, Tüzel E, Ostap EM. A Perspective on the Role of Myosins as Mechanosensors. Biophysical Journal. 110: 2568-76. PMID 27332116 DOI: 10.1016/J.Bpj.2016.05.021  0.407
2016 Pyrpassopoulos S, Arpağ G, Feeser EA, Shuman H, Tüzel E, Ostap EM. Force Generation by Membrane-Associated Myosin-I. Scientific Reports. 6: 25524. PMID 27156719 DOI: 10.1016/J.Bpj.2015.11.2499  0.455
2016 Kee AJ, Yang L, Lucas CA, Greenberg MJ, Martel N, Leong GM, Hughes WE, Cooney GJ, James DE, Ostap EM, Han W, Gunning PW, Hardeman EC. An Actin Filament Population Defined by the Tropomyosin Tpm3.1 Regulates Glucose Uptake. Traffic (Copenhagen, Denmark). 17: 80-1. PMID 26688443 DOI: 10.1111/Tra.12342  0.321
2015 Kast DJ, Zajac AL, Holzbaur EL, Ostap EM, Dominguez R. WHAMM Directs the Arp2/3 Complex to the ER for Autophagosome Biogenesis through an Actin Comet Tail Mechanism. Current Biology : Cb. 25: 1791-7. PMID 26096974 DOI: 10.1016/J.Cub.2015.05.042  0.408
2015 Greenberg MJ, Lin T, Shuman H, Ostap EM. Mechanochemical tuning of myosin-I by the N-terminal region. Proceedings of the National Academy of Sciences of the United States of America. 112: E3337-44. PMID 26056287 DOI: 10.1073/Pnas.1506633112  0.425
2015 Kee AJ, Yang L, Lucas CA, Greenberg MJ, Martel N, Leong GM, Hughes WE, Cooney GJ, James DE, Ostap EM, Han W, Gunning PW, Hardeman EC. An actin filament population defined by the tropomyosin tpm3.1 regulates glucose uptake. Traffic (Copenhagen, Denmark). 16: 691-711. PMID 25783006 DOI: 10.1111/Tra.12282  0.37
2015 McIntosh BB, Holzbaur EL, Ostap EM. Control of the initiation and termination of kinesin-1-driven transport by myosin-Ic and nonmuscle tropomyosin. Current Biology : Cb. 25: 523-9. PMID 25660542 DOI: 10.1016/J.Cub.2014.12.008  0.477
2015 Woody MS, Capitanio M, Ostap EM, Goldman YE. Detection of Ultrafast Mechanical Transitions in β-Cardiac Myosin using High-Speed Optical Trapping Biophysical Journal. 108: 301a-302a. DOI: 10.1016/J.Bpj.2014.11.1640  0.459
2015 Greenberg MJ, Lin T, Shuman H, Ostap EM. Structural Determinants of Myosin I Mechanosensing: The N Terminal Region Biophysical Journal. 108: 25a. DOI: 10.1016/J.Bpj.2014.11.162  0.482
2014 Greenberg MJ, Shuman H, Ostap EM. Inherent force-dependent properties of β-cardiac myosin contribute to the force-velocity relationship of cardiac muscle. Biophysical Journal. 107: L41-4. PMID 25517169 DOI: 10.1016/J.Bpj.2014.11.005  0.365
2014 Ayloo S, Lazarus JE, Dodda A, Tokito M, Ostap EM, Holzbaur EL. Dynactin functions as both a dynamic tether and brake during dynein-driven motility. Nature Communications. 5: 4807. PMID 25185702 DOI: 10.1038/Ncomms5807  0.428
2014 Shuman H, Greenberg MJ, Zwolak A, Lin T, Sindelar CV, Dominguez R, Ostap EM. A vertebrate myosin-I structure reveals unique insights into myosin mechanochemical tuning. Proceedings of the National Academy of Sciences of the United States of America. 111: 2116-21. PMID 24469830 DOI: 10.1073/Pnas.1321022111  0.313
2014 Hendricks AG, Beausang JF, Lewis JH, Lippert L, Shroder D, Ostap EM, Holzbaur EL, Goldman YE. New Methods for Molecular Motor and Cell Motility Research Biophysical Journal. 106: 232a-233a. DOI: 10.1016/J.Bpj.2013.11.1362  0.408
2014 Ostap EM, Greenberg MJ, Zwolak A, Lin T, Sindelar CV, Goldman YE, Dominguez R, Shuman H. Structural, Mechanical, and Biochemical Insights into the Mechanism of Myosin Force Sensing Biophysical Journal. 106: 10a. DOI: 10.1016/J.Bpj.2013.11.101  0.461
2014 Greenberg MJ, Shuman H, Zwolak A, Sindelar C, Dominguez R, Ostap EM. The Structure of Vertebrate Myosin-I Reveals New Insights into Mechanochemical Tuning of Myosins Biophysical Journal. 106: 178a. DOI: 10.1016/J.Bpj.2013.11.1006  0.488
2013 Zwolak A, Yang C, Feeser EA, Ostap EM, Svitkina T, Dominguez R. CARMIL leading edge localization depends on a non-canonical PH domain and dimerization. Nature Communications. 4: 2523. PMID 24071777 DOI: 10.1038/Ncomms3523  0.344
2013 Pyrpassopoulos S, Shuman H, Ostap EM. Method for measuring single-molecule adhesion forces and attachment lifetimes of protein-membrane interactions. Methods in Molecular Biology (Clifton, N.J.). 1046: 389-403. PMID 23868602 DOI: 10.1007/978-1-62703-538-5_24  0.375
2013 Zajac AL, Goldman YE, Holzbaur EL, Ostap EM. Local cytoskeletal and organelle interactions impact molecular-motor- driven early endosomal trafficking. Current Biology : Cb. 23: 1173-80. PMID 23770188 DOI: 10.1016/J.Cub.2013.05.015  0.375
2013 Greenberg MJ, Ostap EM. Regulation and control of myosin-I by the motor and light chain-binding domains. Trends in Cell Biology. 23: 81-9. PMID 23200340 DOI: 10.1016/J.Tcb.2012.10.008  0.421
2013 Zajac AL, Goldman YE, Holzbaur EL, Ostap EM. High-Resolution Imaging of Endocytosed EGF-Quantum Dots Reveals Cellular Factors Regulating the Transitions between the Directed and Diffusive Movement of Early Endosomes Biophysical Journal. 104: 651a-652a. DOI: 10.1016/J.Bpj.2012.11.3598  0.305
2013 Pyrpassopoulos S, Shuman H, Ostap EM. Force Generation by Membrane-Bound Myo1c, a Single Molecule Study Biophysical Journal. 104: 642a. DOI: 10.1016/J.Bpj.2012.11.3547  0.419
2012 Dawicki-McKenna JM, Goldman YE, Ostap EM. Sites of glucose transporter-4 vesicle fusion with the plasma membrane correlate spatially with microtubules. Plos One. 7: e43662. PMID 22916292 DOI: 10.1371/Journal.Pone.0043662  0.348
2012 Greenberg MJ, Lin T, Goldman YE, Shuman H, Ostap EM. Myosin IC generates power over a range of loads via a new tension-sensing mechanism. Proceedings of the National Academy of Sciences of the United States of America. 109: E2433-40. PMID 22908250 DOI: 10.1073/Pnas.1207811109  0.471
2012 Pyrpassopoulos S, Feeser EA, Mazerik JN, Tyska MJ, Ostap EM. Membrane-bound myo1c powers asymmetric motility of actin filaments. Current Biology : Cb. 22: 1688-92. PMID 22863317 DOI: 10.1016/J.Cub.2012.06.069  0.469
2012 Lewis JH, Greenberg MJ, Laakso JM, Shuman H, Ostap EM. Calcium regulation of myosin-I tension sensing. Biophysical Journal. 102: 2799-807. PMID 22735530 DOI: 10.1016/J.Bpj.2012.05.014  0.429
2012 Chen C, Greenberg MJ, Laakso JM, Ostap EM, Goldman YE, Shuman H. Kinetic schemes for post-synchronized single molecule dynamics. Biophysical Journal. 102: L23-5. PMID 22455931 DOI: 10.1016/J.Bpj.2012.01.054  0.321
2012 Greenberg MJ, Lin T, Goldman YE, Shuman H, Ostap EM. Myo1c is Built for Sustained Power Under Load, not Tension Sensing Biophysical Journal. 102: 566a. DOI: 10.1016/J.Bpj.2011.11.3085  0.409
2012 Hendricks AG, Zajac AL, Schroeder HW, Maday S, Ostap EM, Goldman YE, Holzbaur EL. Coordination of Multiple Motors Bound to Intracellular Cargos Biophysical Journal. 102: 213a. DOI: 10.1016/J.Bpj.2011.11.1165  0.414
2011 Lin T, Greenberg MJ, Moore JR, Ostap EM. A hearing loss-associated myo1c mutation (R156W) decreases the myosin duty ratio and force sensitivity. Biochemistry. 50: 1831-8. PMID 21265502 DOI: 10.1021/Bi1016777  0.422
2011 Shuman H, Laakso JM, Ostap EM. Conformational Dynamics of Nucleotide-Free Myo1b Biophysical Journal. 100: 116a. DOI: 10.1016/J.Bpj.2010.12.840  0.409
2011 McKenna JMD, Goldman YE, Ostap EM. Spatial Organization of Microtubules Specifies Sites of Glucose Transporter-4 Vesicle Fusion with the Plasma Membrane Biophysical Journal. 100: 409a. DOI: 10.1016/J.Bpj.2010.12.2425  0.334
2010 Pyrpassopoulos S, Shuman H, Ostap EM. Single-molecule adhesion forces and attachment lifetimes of myosin-I phosphoinositide interactions. Biophysical Journal. 99: 3916-22. PMID 21156133 DOI: 10.1016/J.Bpj.2010.10.043  0.442
2010 Feeser EA, Ignacio CM, Krendel M, Ostap EM. Myo1e binds anionic phospholipids with high affinity. Biochemistry. 49: 9353-60. PMID 20860408 DOI: 10.1021/Bi1012657  0.437
2010 Laakso JM, Lewis JH, Shuman H, Ostap EM. Control of myosin-I force sensing by alternative splicing Proceedings of the National Academy of Sciences of the United States of America. 107: 698-702. PMID 20080738 DOI: 10.1073/Pnas.0911426107  0.487
2010 Patino-Lopez G, Aravind L, Dong X, Kruhlak MJ, Ostap EM, Shaw S. Myosin 1G is an abundant class I myosin in lymphocytes whose localization at the plasma membrane depends on its ancient divergent pleckstrin homology (PH) domain (Myo1PH). The Journal of Biological Chemistry. 285: 8675-86. PMID 20071333 DOI: 10.1074/Jbc.M109.086959  0.382
2010 Pyrpassopoulos S, Shuman H, Ostap EM. Kinetics of Myosin-I-Membrane Detachment Under Load Biophysical Journal. 98: 562a. DOI: 10.1016/J.Bpj.2009.12.3044  0.447
2010 Lewis JH, Laakso J, Lin T, Shuman H, Ostap EM. Calcium Regulation of myo1b Tension Sensing Biophysical Journal. 98: 229a. DOI: 10.1016/J.Bpj.2009.12.1238  0.4
2009 McKenna JM, Ostap EM. Kinetics of the interaction of myo1c with phosphoinositides. The Journal of Biological Chemistry. 284: 28650-9. PMID 19706607 DOI: 10.1074/Jbc.M109.049791  0.443
2009 Bethoney KA, King MC, Hinshaw JE, Ostap EM, Lemmon MA. A possible effector role for the pleckstrin homology (PH) domain of dynamin. Proceedings of the National Academy of Sciences of the United States of America. 106: 13359-64. PMID 19666604 DOI: 10.1073/Pnas.0906945106  0.371
2009 Sun Y, McKenna JD, Murray JM, Ostap EM, Goldman YE. Parallax: high accuracy three-dimensional single molecule tracking using split images. Nano Letters. 9: 2676-82. PMID 19496608 DOI: 10.1021/Nl901129J  0.33
2009 De La Cruz EM, Ostap EM. Kinetic and equilibrium analysis of the myosin ATPase. Methods in Enzymology. 455: 157-92. PMID 19289206 DOI: 10.1016/S0076-6879(08)04206-7  0.687
2009 Dawicki McKenna JM, Ostap EM. Kinetics Of Myo1c Association To And Dissociation From Phosphoinositide-containing Vesicles Biophysical Journal. 96: 139a. DOI: 10.1016/J.Bpj.2008.12.3870  0.369
2009 Pyrpassopoulos S, Shuman H, Ostap EM. Single-molecule Measurements Of Myo1c-PIP2 Detachment Forces Using Optical Tweezers Biophysical Journal. 96: 139a. DOI: 10.1016/J.Bpj.2008.12.3867  0.451
2009 Laakso JM, Shuman H, Ostap EM. Force Dependence of a Myo1b Truncation Mutant Biophysical Journal. 96: 138a-139a. DOI: 10.1016/J.Bpj.2008.12.3866  0.428
2008 Ostap EM. Tropomyosins as discriminators of myosin function. Advances in Experimental Medicine and Biology. 644: 273-82. PMID 19209828 DOI: 10.1007/978-0-387-85766-4_20  0.413
2008 Laakso JM, Lewis JH, Shuman H, Ostap EM. Myosin I can act as a molecular force sensor Science. 321: 133-136. PMID 18599791 DOI: 10.1126/Science.1159419  0.46
2007 Tang N, Lin T, Yang J, Foskett JK, Ostap EM. CIB1 and CaBP1 bind to the myo1c regulatory domain. Journal of Muscle Research and Cell Motility. 28: 285-91. PMID 17994197 DOI: 10.1007/S10974-007-9124-7  0.398
2007 Manceva S, Lin T, Pham H, Lewis JH, Goldman YE, Ostap EM. Calcium regulation of calmodulin binding to and dissociation from the myo1c regulatory domain. Biochemistry. 46: 11718-26. PMID 17910470 DOI: 10.1021/Bi700894H  0.42
2007 Bach TL, Kerr WT, Wang Y, Bauman EM, Kine P, Whiteman EL, Morgan RS, Williamson EK, Ostap EM, Burkhardt JK, Koretzky GA, Birnbaum MJ, Abrams CS. PI3K regulates pleckstrin-2 in T-cell cytoskeletal reorganization. Blood. 109: 1147-55. PMID 17008542 DOI: 10.1182/Blood-2006-02-001339  0.382
2006 Lewis JH, Lin T, Hokanson DE, Ostap EM. Temperature dependence of nucleotide association and kinetic characterization of myo1b. Biochemistry. 45: 11589-97. PMID 16981718 DOI: 10.1021/Bi0611917  0.436
2006 Hokanson DE, Laakso JM, Lin T, Sept D, Ostap EM. Myo1c binds phosphoinositides through a putative pleckstrin homology domain. Molecular Biology of the Cell. 17: 4856-65. PMID 16971510 DOI: 10.1091/Mbc.E06-05-0449  0.414
2006 Hokanson DE, Ostap EM. Myo1c binds tightly and specifically to phosphatidylinositol 4,5-bisphosphate and inositol 1,4,5-trisphosphate. Proceedings of the National Academy of Sciences of the United States of America. 103: 3118-23. PMID 16492791 DOI: 10.1073/Pnas.0505685103  0.454
2005 Lin T, Tang N, Ostap EM. Biochemical and motile properties of Myo1b splice isoforms. The Journal of Biological Chemistry. 280: 41562-7. PMID 16254000 DOI: 10.1074/Jbc.M508653200  0.462
2004 De La Cruz EM, Ostap EM. Relating biochemistry and function in the myosin superfamily. Current Opinion in Cell Biology. 16: 61-7. PMID 15037306 DOI: 10.1016/J.Ceb.2003.11.011  0.652
2003 Shaw MA, Ostap EM, Goldman YE. Mechanism of inhibition of skeletal muscle actomyosin by N-benzyl-p-toluenesulfonamide. Biochemistry. 42: 6128-35. PMID 12755615 DOI: 10.1021/Bi026964F  0.437
2003 Ostap EM, Maupin P, Doberstein SK, Baines IC, Korn ED, Pollard TD. Dynamic localization of myosin-I to endocytic structures in Acanthamoeba. Cell Motility and the Cytoskeleton. 54: 29-40. PMID 12451593 DOI: 10.1002/Cm.10081  0.675
2002 Ostap EM. 2,3-Butanedione monoxime (BDM) as a myosin inhibitor. Journal of Muscle Research and Cell Motility. 23: 305-8. PMID 12630704 DOI: 10.1023/A:1022047102064  0.397
2002 Ostap EM, Lin T, Rosenfeld SS, Tang N. Mechanism of regulation of Acanthamoeba myosin-IC by heavy-chain phosphorylation. Biochemistry. 41: 12450-6. PMID 12369835 DOI: 10.1021/Bi0262193  0.51
2002 Tang N, Lin T, Ostap EM. Dynamics of myo1c (myosin-ibeta ) lipid binding and dissociation. The Journal of Biological Chemistry. 277: 42763-8. PMID 12221091 DOI: 10.1074/Jbc.M206388200  0.427
2002 Yengo CM, De la Cruz EM, Safer D, Ostap EM, Sweeney HL. Kinetic characterization of the weak binding states of myosin V. Biochemistry. 41: 8508-17. PMID 12081502 DOI: 10.1021/Bi015969U  0.68
2002 El Mezgueldi M, Tang N, Rosenfeld SS, Ostap EM. The kinetic mechanism of Myo1e (human myosin-IC). The Journal of Biological Chemistry. 277: 21514-21. PMID 11940582 DOI: 10.1074/Jbc.M200713200  0.505
2001 Gillespie PG, Albanesi JP, Bahler M, Bement WM, Berg JS, Burgess DR, Burnside B, Cheney RE, Corey DP, Coudrier E, de Lanerolle P, Hammer JA, Hasson T, Holt JR, Hudspeth AJ, ... ... Ostap EM, et al. Myosin-I nomenclature. The Journal of Cell Biology. 155: 703-4. PMID 11724811 DOI: 10.1083/Jcb.200110032  0.669
2001 Tang N, Ostap EM. Motor domain-dependent localization of myo1b (myr-1). Current Biology : Cb. 11: 1131-5. PMID 11509238 DOI: 10.1016/S0960-9822(01)00320-7  0.486
2001 De La Cruz EM, Ostap EM, Sweeney HL. Kinetic mechanism and regulation of myosin VI. The Journal of Biological Chemistry. 276: 32373-81. PMID 11423557 DOI: 10.1074/Jbc.M104136200  0.701
2000 De La Cruz EM, Wells AL, Sweeney HL, Ostap EM. Actin and light chain isoform dependence of myosin V kinetics. Biochemistry. 39: 14196-202. PMID 11087368 DOI: 10.1021/Bi001701B  0.656
2000 De La Cruz EM, Sweeney HL, Ostap EM. ADP inhibition of myosin V ATPase activity. Biophysical Journal. 79: 1524-9. PMID 10969013 DOI: 10.1016/S0006-3495(00)76403-4  0.673
2000 De La Cruz EM, Ostap EM, Brundage RA, Reddy KS, Sweeney HL, Safer D. Thymosin-beta(4) changes the conformation and dynamics of actin monomers. Biophysical Journal. 78: 2516-27. PMID 10777749 DOI: 10.1016/S0006-3495(00)76797-X  0.682
1999 Lee WL, Ostap EM, Zot HG, Pollard TD. Organization and ligand binding properties of the tail of Acanthamoeba myosin-IA. Identification of an actin-binding site in the basic (tail homology-1) domain. The Journal of Biological Chemistry. 274: 35159-71. PMID 10574999 DOI: 10.1074/Jbc.274.49.35159  0.663
1999 De La Cruz EM, Wells AL, Rosenfeld SS, Ostap EM, Sweeney HL. The kinetic mechanism of myosin V. Proceedings of the National Academy of Sciences of the United States of America. 96: 13726-31. PMID 10570140 DOI: 10.1073/Pnas.96.24.13726  0.7
1998 Jontes JD, Ostap EM, Pollard TD, Milligan RA. Three-dimensional structure of Acanthamoeba castellanii myosin-IB (MIB) determined by cryoelectron microscopy of decorated actin filaments. The Journal of Cell Biology. 141: 155-62. PMID 9531555 DOI: 10.1083/Jcb.141.1.155  0.6
1997 Jontes JD, Milligan RA, Pollard TD, Ostap EM. Kinetic characterization of brush border myosin-I ATPase. Proceedings of the National Academy of Sciences of the United States of America. 94: 14332-7. PMID 9405612 DOI: 10.1073/pnas.94.26.14332  0.534
1996 Pollard TD, Ostap EM. The chemical mechanism of myosin-I: implications for actin-based motility and the evolution of the myosin family of motor proteins. Cell Structure and Function. 21: 351-6. PMID 9118240 DOI: 10.1247/Csf.21.351  0.666
1996 Ostap EM, Pollard TD. Overlapping functions of myosin-I isoforms? The Journal of Cell Biology. 133: 221-4. PMID 8609156 DOI: 10.1083/Jcb.133.2.221  0.464
1996 Ostap EM, Pollard TD. Biochemical kinetic characterization of the Acanthamoeba myosin-I ATPase. The Journal of Cell Biology. 132: 1053-60. PMID 8601584 DOI: 10.1083/Jcb.132.6.1053  0.625
1995 Thomas DD, Ramachandran S, Roopnarine O, Hayden DW, Ostap EM, Rayment I, Reisler K, Kinosita K. The mechanism of force generation in myosin: A disorder-to-order transition, coupled to internal structural changes Biophysical Journal. 68: 135s-141s. PMID 7787056  0.34
1993 Ostap EM, White HD, Thomas DD. Transient detection of spin-labeled myosin subfragment 1 conformational states during ATP hydrolysis. Biochemistry. 32: 6712-20. PMID 8392368 DOI: 10.1021/Bi00077A026  0.376
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