Year |
Citation |
Score |
2023 |
Kitchens WH, Larsen CP, Badell IR. Costimulatory Blockade and Solid Organ Transplantation: The Past, Present, and Future. Kidney International Reports. 8: 2529-2545. PMID 38106575 DOI: 10.1016/j.ekir.2023.08.037 |
0.337 |
|
2023 |
Johnson AC, Zhang J, Karadkhele G, Gragert L, Hertzberg V, Larsen CP. Belatacept with time-limited tacrolimus coimmunosuppression modifies the 3-year risk of eplet mismatch in kidney transplantation. American Journal of Transplantation : Official Journal of the American Society of Transplantation and the American Society of Transplant Surgeons. PMID 37778459 DOI: 10.1016/j.ajt.2023.09.011 |
0.307 |
|
2023 |
Lovasik BP, Kim SC, Higginbotham L, Wakwe W, Mathews DV, Breeden C, Farris AB, Larsen CP, Ford ML, Nadler S, Adams AB. CD28-Selective Inhibition Prolongs Non-Human Primate Kidney Transplant Survival. Biorxiv : the Preprint Server For Biology. PMID 37205571 DOI: 10.1101/2023.05.03.539333 |
0.671 |
|
2023 |
Werbel WA, Karaba AH, Po-Yu Chiang T, Massie AB, Brown DM, Watson N, Chahoud M, Thompson EA, Johnson AC, Avery RK, Cochran WV, Warren D, Liang T, Fribourg M, Huerta C, ... ... Larsen CP, et al. Persistent SARS-CoV-2-specific immune defects in kidney transplant recipients following third mRNA vaccine doses. American Journal of Transplantation : Official Journal of the American Society of Transplantation and the American Society of Transplant Surgeons. PMID 36966905 DOI: 10.1016/j.ajt.2023.03.014 |
0.349 |
|
2023 |
Johnson AC, Karadkhele GM, Shenvi N, Easley KA, Larsen CP, Badell IR. Three-year Outcomes After Conversion From Monthly to Every 2-month Belatacept Maintenance Therapy in Kidney Transplant Recipients: Results From a Randomized Controlled Trial. Transplantation Direct. 9: e1449. PMID 36875938 DOI: 10.1097/TXD.0000000000001449 |
0.333 |
|
2022 |
Prokhnevska N, Cardenas MA, Valanparambil RM, Sobierajska E, Barwick BG, Jansen C, Reyes Moon A, Gregorova P, delBalzo L, Greenwald R, Bilen MA, Alemozaffar M, Joshi S, Cimmino C, Larsen C, et al. CD8 T cell activation in cancer comprises an initial activation phase in lymph nodes followed by effector differentiation within the tumor. Immunity. PMID 36580918 DOI: 10.1016/j.immuni.2022.12.002 |
0.303 |
|
2022 |
Iglesias M, Brennan DC, Larsen CP, Raimondi G. Targeting inflammation and immune activation to improve CTLA4-Ig-based modulation of transplant rejection. Frontiers in Immunology. 13: 926648. PMID 36119093 DOI: 10.3389/fimmu.2022.926648 |
0.41 |
|
2022 |
Johnson AC, Karadkhele G, Magua W, Vasanth P, Larsen CP. Longitudinal Evaluation of Cytopenias in the Renal Transplant Population. Transplantation Direct. 8: e1339. PMID 35651583 DOI: 10.1097/TXD.0000000000001339 |
0.318 |
|
2021 |
Badell IR, Bray RA, Elbein R, Chami AS, Easley KA, Pastan SO, Guasch A, Gebel HM, Adams AB, Larsen CP. Belatacept in Kidney Transplant Recipients With Failed Allografts for the Prevention of Humoral Sensitization: A Pilot Randomized Controlled Trial. Transplantation. 105: e395-e396. PMID 34818307 DOI: 10.1097/TP.0000000000003852 |
0.578 |
|
2021 |
Karadkhele G, Duneton C, Garro R, Badell IR, Pearson TC, Larsen CP, Hogan J. Temporal trends and current use of de novo belatacept in kidney transplant recipients in the United States. Clinical Transplantation. 36: e14531. PMID 34757651 DOI: 10.1111/ctr.14531 |
0.363 |
|
2021 |
Cristea O, Karadkhele G, Kitchens WH, Vasanth P, Larsen CP, Badell IR. Belatacept Conversion in Kidney After Liver Transplantation. Transplantation Direct. 7: e780. PMID 34712780 DOI: 10.1097/TXD.0000000000001229 |
0.328 |
|
2021 |
Lentine KL, Pastan S, Mohan S, Reese PP, Leichtman A, Delmonico FL, Danovitch GM, Larsen CP, Harshman L, Wiseman A, Kramer HJ, Vassalotti J, Joseph J, Longino K, Cooper M, et al. A Roadmap for Innovation to Advance Transplant Access and Outcomes: A Position Statement From the National Kidney Foundation. American Journal of Kidney Diseases : the Official Journal of the National Kidney Foundation. PMID 34330526 DOI: 10.1053/j.ajkd.2021.05.007 |
0.339 |
|
2021 |
Zhang W, Morris AB, Peek EV, Karadkhele G, Robertson JM, Kissick HT, Larsen CP. CMV Status Drives Distinct Trajectories of CD4+ T Cell Differentiation. Frontiers in Immunology. 12: 620386. PMID 33936035 DOI: 10.3389/fimmu.2021.620386 |
0.44 |
|
2021 |
Badell IR, Parsons RF, Karadkhele G, Cristea O, Mead S, Thomas S, Robertson JM, Kim GS, Hanfelt JJ, Pastan SO, Larsen CP. Every two-month belatacept maintenance therapy in kidney transplant recipients greater than one-year post-transplant: a randomized, non-inferiority trial. American Journal of Transplantation : Official Journal of the American Society of Transplantation and the American Society of Transplant Surgeons. PMID 33583120 DOI: 10.1111/ajt.16538 |
0.306 |
|
2020 |
Kirk AD, Adams AB, Durrbach A, Ford ML, Hildeman DA, Larsen CP, Vincenti F, Wojciechowski D, Woodle ES. Optimization of De Novo Belatacept-Based Immunosuppression Administered to Renal Transplant Recipients. American Journal of Transplantation : Official Journal of the American Society of Transplantation and the American Society of Transplant Surgeons. PMID 33128812 DOI: 10.1111/ajt.16386 |
0.604 |
|
2020 |
Markmann JF, Rickels MR, Eggerman TL, Bridges ND, Lafontant DE, Qidwai J, Foster E, Clarke WR, Kamoun M, Alejandro R, Bellin M, Chaloner K, Czarniecki CW, Goldstein JS, Hering BJ, ... ... Larsen CP, et al. Phase 3 Trial of Human Islet-after-Kidney Transplantation in Type 1 Diabetes. American Journal of Transplantation : Official Journal of the American Society of Transplantation and the American Society of Transplant Surgeons. PMID 32627352 DOI: 10.1111/Ajt.16174 |
0.424 |
|
2020 |
Mannon RB, Armstrong B, Stock PG, Mehta AK, Farris AB, Watson N, Morrison Y, Sarwal M, Sigdel T, Bridges N, Robien M, Newell KA, Larsen CP. Avoidance of CNI and Steroids Using Belatacept - Results of the Clinical Trials in Organ Transplantation 16 Trial. American Journal of Transplantation : Official Journal of the American Society of Transplantation and the American Society of Transplant Surgeons. PMID 32558199 DOI: 10.1111/Ajt.16152 |
0.408 |
|
2020 |
Karadkhele G, Hogan J, Magua W, Zhang W, Badell IR, Mehta A, Lyon M, Pastan S, Pearson TC, Larsen CP. CMV high-risk status and post-transplant outcomes in kidney transplant recipients treated with Belatacept. American Journal of Transplantation : Official Journal of the American Society of Transplantation and the American Society of Transplant Surgeons. PMID 32519434 DOI: 10.1111/Ajt.16132 |
0.446 |
|
2020 |
Krummey SM, Morris AB, Jacobs JR, McGuire DJ, Ando S, Tong KP, Zhang W, Robertson J, Guasch SA, Araki K, Larsen CP, Evavold BD, Kissick HT, Ford ML. CD45RB Status of CD8 T Cell Memory Defines T Cell Receptor Affinity and Persistence. Cell Reports. 30: 1282-1291.e5. PMID 32023448 DOI: 10.1016/J.Celrep.2020.01.016 |
0.416 |
|
2019 |
Parsons RF, Larsen CP, Pearson TC, Badell IR. Belatacept and CD28 Costimulation Blockade: Preventingand Reducing Alloantibodies over the Long Term. Current Transplantation Reports. 6: 277-284. PMID 32158639 DOI: 10.1007/S40472-019-00260-3 |
0.537 |
|
2019 |
Parsons RF, Zahid A, Bumb S, Decker H, Clifford Sullivan H, Lee FE, Badell IR, Ford ML, Larsen CP, Pearson TC, Jackson AM, Chen DF, Levine M, Kamoun M, Bray RA, et al. The impact of belatacept on third party HLA alloantibodies in highly sensitized kidney transplant recipients. American Journal of Transplantation : Official Journal of the American Society of Transplantation and the American Society of Transplant Surgeons. PMID 31452332 DOI: 10.1111/Ajt.15585 |
0.427 |
|
2019 |
Patzer RE, Larsen CP. Patient Navigators in Transplantation-Where Do We Go From Here? Transplantation. 103: 1076-1077. PMID 31246931 DOI: 10.1097/Tp.0000000000002451 |
0.424 |
|
2019 |
Anderson DJ, Lo DJ, Leopardi F, Song M, Strobert EA, Jenkins JB, Larsen CP, Kirk AD. Corticosteroids and Methotrexate as Adjuvants to Costimulation Blockade in Nonhuman Primate Renal Transplantation. Clinical Transplantation. e13568. PMID 31006146 DOI: 10.1111/Ctr.13568 |
0.49 |
|
2019 |
Kim SC, Mathews DV, Breeden CP, Higginbotham LB, Ladowski J, Martens G, Stephenson A, Farris AB, Strobert EA, Jenkins J, Walters EM, Larsen CP, Tector M, Tector AJ, Adams AB. Long-Term Survival of Pig-to-Rhesus Macaque Renal Xenografts is Dependent on CD4 T cell Depletion. American Journal of Transplantation : Official Journal of the American Society of Transplantation and the American Society of Transplant Surgeons. PMID 30821922 DOI: 10.1111/Ajt.15329 |
0.717 |
|
2019 |
Badell IR, Karadkhele GM, Vasanth P, Brad Farris A, Robertson JM, Larsen CP. Abatacept as rescue immunosuppression after calcineurin inhibitor treatment failure in renal transplantation. American Journal of Transplantation : Official Journal of the American Society of Transplantation and the American Society of Transplant Surgeons. PMID 30768841 DOI: 10.1111/Ajt.15319 |
0.481 |
|
2019 |
Gangappa S, Wrammert J, Wang D, Li ZN, Liepkalns JS, Cao W, Chen J, Levine MZ, Stevens J, Sambhara S, Begley B, Mehta A, Pearson TC, Ahmed R, Larsen CP. Kinetics of antibody response to influenza vaccination in renal transplant recipients. Transplant Immunology. PMID 30664927 DOI: 10.1016/J.Trim.2019.01.001 |
0.381 |
|
2018 |
Gopalsamy SN, Woodworth MH, Wang T, Carpentieri CT, Mehta N, Friedman-Moraco RJ, Mehta AK, Larsen CP, Kraft CS. The Use of Microbiome Restoration Therapeutics to Eliminate Intestinal Colonization With Multidrug-Resistant Organisms. The American Journal of the Medical Sciences. 356: 433-440. PMID 30384952 DOI: 10.1016/J.Amjms.2018.08.015 |
0.317 |
|
2018 |
Mathews DV, Dong Y, Higginbotham LB, Kim SC, Breeden CP, Stobert EA, Jenkins J, Tso JY, Larsen CP, Adams AB. CD122 signaling in CD8+ memory T cells drives costimulation-independent rejection. The Journal of Clinical Investigation. PMID 30222140 DOI: 10.1172/Jci95914 |
0.697 |
|
2018 |
Patzer RE, Larsen CP. Patient Navigators in Transplantation - where do we go from here? Transplantation. PMID 30211829 DOI: 10.1097/TP.0000000000002451 |
0.311 |
|
2018 |
Basu M, Petgrave-Nelson L, Smith KD, Perryman JP, Clark K, Pastan SO, Pearson TC, Larsen CP, Paul S, Patzer RE. Transplant Center Patient Navigator and Access to Transplantation among High-Risk Population: A Randomized, Controlled Trial. Clinical Journal of the American Society of Nephrology : Cjasn. PMID 29581107 DOI: 10.2215/Cjn.08600817 |
0.446 |
|
2018 |
Bray RA, Gebel HM, Townsend R, Roberts ME, Polinsky M, Yang L, Meier-Kriesche HU, Larsen CP. Posttransplant Reduction in Pre-Existing Donor-Specific Antibody Levels After Belatacept- vs. Cyclosporine-Based Immunosuppression: Post-Hoc Analyses of BENEFIT and BENEFIT-EXT. American Journal of Transplantation : Official Journal of the American Society of Transplantation and the American Society of Transplant Surgeons. PMID 29573335 DOI: 10.1111/Ajt.14738 |
0.42 |
|
2018 |
Bray RA, Gebel HM, Townsend R, Roberts ME, Polinsky M, Yang L, Meier-Kriesche HU, Larsen CP. De Novo Donor-Specific Antibodies in Belatacept-Treated vs. Cyclosporine-Treated Kidney Transplant Recipients: Post-Hoc Analyses of the Randomized Phase III BENEFIT and BENEFIT-EXT Studies. American Journal of Transplantation : Official Journal of the American Society of Transplantation and the American Society of Transplant Surgeons. PMID 29509295 DOI: 10.1111/Ajt.14721 |
0.425 |
|
2018 |
Florman S, Vincenti F, Durrbach A, Abouljoud M, Bresnahan B, Garcia VD, Mulloy L, Rice K, Rostaing L, Zayas C, Calderon K, Meier-Kriesche U, Polinsky M, Yang L, Pestana JM, ... Larsen CP, et al. Outcomes at 7 years post-transplant in black versus non-black kidney transplant recipients administered belatacept or cyclosporine in BENEFIT and BENEFIT-EXT. Clinical Transplantation. PMID 29461660 DOI: 10.1111/Ctr.13225 |
0.416 |
|
2018 |
Patzer RE, McPherson L, Basu M, Mohan S, Wolf M, Chiles M, Russell A, Gander JC, Friedewald JJ, Ladner D, Larsen CP, Pearson T, Pastan S. Effect of the iChoose Kidney Decision Aid in Improving Knowledge about Treatment Options among Transplant Candidates: a Randomized Controlled Trial. American Journal of Transplantation : Official Journal of the American Society of Transplantation and the American Society of Transplant Surgeons. PMID 29446209 DOI: 10.1111/Ajt.14693 |
0.41 |
|
2017 |
Lovasik BP, Zhang R, Hockenberry JM, Schrager JD, Pastan SO, Adams AB, Mohan S, Larsen CP, Patzer RE. Emergency Department Utilization among Kidney Transplant Recipients in the United States. American Journal of Transplantation : Official Journal of the American Society of Transplantation and the American Society of Transplant Surgeons. PMID 29116680 DOI: 10.1111/Ajt.14578 |
0.586 |
|
2017 |
Vincenti F, Blancho G, Durrbach A, Grannas G, Grinyó J, Meier-Kriesche HU, Polinsky M, Yang L, Larsen CP. Ten-Year Outcomes in a Randomized Phase II Study of Kidney Transplant Recipients Administered Belatacept 4-Weekly or 8-Weekly. American Journal of Transplantation : Official Journal of the American Society of Transplantation and the American Society of Transplant Surgeons. PMID 28758341 DOI: 10.1111/Ajt.14452 |
0.331 |
|
2017 |
Newell KA, Mehta AK, Larsen CP, Stock PG, Farris AB, Mehta SG, Ikle D, Armstrong B, Morrison Y, Bridges N, Robien M, Mannon RB. Lessons learned: Early termination of a randomized trial of calcineurin inhibitor and corticosteroid avoidance using Belatacept. American Journal of Transplantation : Official Journal of the American Society of Transplantation and the American Society of Transplant Surgeons. PMID 28556519 DOI: 10.1111/Ajt.14377 |
0.335 |
|
2017 |
Adams AB, Goldstein J, Garrett C, Zhang R, Patzer RE, Newell KA, Turgeon NA, Chami AS, Guasch A, Kirk AD, Pastan SO, Pearson TC, Larsen CP. Belatacept Combined with Transient Calcineurin Inhibitor Therapy Prevents Rejection and Promotes Improved Long-Term Renal Allograft Function. American Journal of Transplantation : Official Journal of the American Society of Transplantation and the American Society of Transplant Surgeons. PMID 28544101 DOI: 10.1111/Ajt.14353 |
0.634 |
|
2017 |
Mathews DV, Wakwe WC, Kim SC, Lowe MC, Breeden C, Roberts ME, Farris AB, Strobert EA, Jenkins JB, Larsen CP, Ford ML, Townsend R, Adams AB. Belatacept Resistant Rejection is Associated with CD28(+) Memory CD8 T cells. American Journal of Transplantation : Official Journal of the American Society of Transplantation and the American Society of Transplant Surgeons. PMID 28502128 DOI: 10.1111/Ajt.14349 |
0.704 |
|
2017 |
Cortes-Cerisuelo M, Laurie SJ, Mathews DV, Winterberg PD, Larsen CP, Adams AB, Ford ML. Increased Pre-Transplant Frequency of CD28(+) CD4(+) TEM Predicts Belatacept-Resistant Rejection in Human Renal Transplant Recipients. American Journal of Transplantation : Official Journal of the American Society of Transplantation and the American Society of Transplant Surgeons. PMID 28502091 DOI: 10.1111/Ajt.14350 |
0.702 |
|
2017 |
Kitchens WH, Dong Y, Mathews DV, Breeden CP, Strobert E, Fuentes ME, Larsen CP, Ford ML, Adams AB. Interruption of OX40L signaling prevents costimulation blockade-resistant allograft rejection. Jci Insight. 2: e90317. PMID 28289708 DOI: 10.1172/Jci.Insight.90317 |
0.683 |
|
2017 |
Kim SC, Wakwe W, Higginbotham LB, Mathews DV, Breeden CP, Stephenson AC, Jenkins J, Strobert E, Price K, Price L, Kuhn R, Wang H, Yamniuk A, Suchard S, Farris AB, ... ... Larsen CP, et al. Fc-Silent Anti-CD154 Domain Antibody Effectively Prevents Non-Human Primate Renal Allograft Rejection. American Journal of Transplantation : Official Journal of the American Society of Transplantation and the American Society of Transplant Surgeons. PMID 28097811 DOI: 10.1111/Ajt.14197 |
0.674 |
|
2016 |
Lynch RJ, Zhang R, Patzer RE, Larsen CP, Adams AB. First-year waitlist hospitalization and subsequent waitlist and transplant outcome. American Journal of Transplantation : Official Journal of the American Society of Transplantation and the American Society of Transplant Surgeons. PMID 27664797 DOI: 10.1111/Ajt.14061 |
0.605 |
|
2016 |
Adams AB, Ford ML, Larsen CP. Costimulation Blockade in Autoimmunity and Transplantation: The CD28 Pathway. Journal of Immunology (Baltimore, Md. : 1950). 197: 2045-50. PMID 27591335 DOI: 10.4049/Jimmunol.1601135 |
0.674 |
|
2016 |
Zheng HB, Watkins B, Tkachev V, Yu S, Tran D, Furlan S, Zeleski K, Singh K, Hamby K, Hotchkiss C, Lane J, Gumber S, Adams A, Cendales L, Kirk AD, ... ... Larsen CP, et al. The Knife's Edge of Tolerance: Inducing Stable Multilineage Mixed Chimerism But With A Significant Risk of CMV Reactivation and Disease in Rhesus Macaques. American Journal of Transplantation : Official Journal of the American Society of Transplantation and the American Society of Transplant Surgeons. PMID 27500470 DOI: 10.1111/Ajt.14006 |
0.698 |
|
2016 |
Krummey SM, Chen CW, Guasch SA, Liu D, Wagener M, Larsen CP, Ford ML. Enhanced Requirement for TNFR2 in Graft Rejection Mediated by Low-Affinity Memory CD8+ T Cells during Heterologous Immunity. Journal of Immunology (Baltimore, Md. : 1950). PMID 27481849 DOI: 10.4049/Jimmunol.1502680 |
0.47 |
|
2016 |
Florman S, Becker T, Bresnahan B, Chevaile-Ramos A, Carvalho D, Grannas G, Muehlbacher F, O'Connell PJ, Meier-Kriesche U, Larsen CP. Efficacy and safety outcomes of extended-criteria donor kidneys by subtype: Subgroup analysis of BENEFIT-EXT at 7-years posttransplant. American Journal of Transplantation : Official Journal of the American Society of Transplantation and the American Society of Transplant Surgeons. PMID 27232116 DOI: 10.1111/Ajt.13886 |
0.402 |
|
2016 |
Krummey SM, Martinez RJ, Andargachew R, Liu D, Wagener M, Kohlmeier JE, Evavold BD, Larsen CP, Ford ML. Low-Affinity Memory CD8+ T Cells Mediate Robust Heterologous Immunity. Journal of Immunology (Baltimore, Md. : 1950). PMID 26864034 DOI: 10.4049/Jimmunol.1500639 |
0.49 |
|
2016 |
Vincenti F, Rostaing L, Grinyo J, Rice K, Steinberg S, Gaite L, Moal MC, Mondragon-Ramirez GA, Kothari J, Polinsky MS, Meier-Kriesche HU, Munier S, Larsen CP. Belatacept and Long-Term Outcomes in Kidney Transplantation. The New England Journal of Medicine. 374: 333-43. PMID 26816011 DOI: 10.1056/Nejmoa1506027 |
0.447 |
|
2015 |
Lynch RJ, Zhang R, Patzer RE, Larsen CP, Adams AB. Waitlist Hospital Admissions Predict Resource Utilization and Survival After Renal Transplantation. Annals of Surgery. PMID 26720436 DOI: 10.1097/Sla.0000000000001574 |
0.592 |
|
2015 |
Patzer RE, Basu M, Larsen CP, Pastan SO, Mohan S, Patzer M, Konomos M, McClellan WM, Lea J, Howard D, Gander J, Arriola KJ. iChoose Kidney: A Clinical Decision Aid for Kidney Transplantation Versus Dialysis Treatment. Transplantation. PMID 26714121 DOI: 10.1097/Tp.0000000000001019 |
0.405 |
|
2015 |
Anderson DJ, Lo DJ, Leopardi F, Song M, Turgeon NA, Strobert EA, Jenkins JB, Wang R, Reimann KA, Larsen CP, Kirk AD. Anti-LFA-1 Therapy in a Nonhuman Primate Renal Transplant Model of Costimulation Blockade Resistant Rejection. American Journal of Transplantation : Official Journal of the American Society of Transplantation and the American Society of Transplant Surgeons. PMID 26602755 DOI: 10.1111/Ajt.13628 |
0.445 |
|
2015 |
Badell IR, Kitchens WH, Wagener ME, Lukacher AE, Larsen CP, Ford ML. Pathogen Stimulation History Impacts Donor-Specific CD8(+) T Cell Susceptibility to Costimulation/Integrin Blockade-Based Therapy. American Journal of Transplantation : Official Journal of the American Society of Transplantation and the American Society of Transplant Surgeons. PMID 26228897 DOI: 10.1111/Ajt.13399 |
0.472 |
|
2015 |
Higginbotham L, Mathews D, Breeden CA, Song M, Farris AB, Larsen CP, Ford ML, Lutz AJ, Tector M, Newell KA, Tector AJ, Adams AB. Pre-transplant antibody screening and anti-CD154 costimulation blockade promote long-term xenograft survival in a pig-to-primate kidney transplant model. Xenotransplantation. 22: 221-30. PMID 25847130 DOI: 10.1111/Xen.12166 |
0.669 |
|
2015 |
Martin BM, Samy KP, Lowe MC, Thompson PW, Cano J, Farris AB, Song M, Dove CR, Leopardi FV, Strobert EA, Jenkins JB, Collins BH, Larsen CP, Kirk AD. Dual islet transplantation modeling of the instant blood-mediated inflammatory reaction. American Journal of Transplantation : Official Journal of the American Society of Transplantation and the American Society of Transplant Surgeons. 15: 1241-52. PMID 25702898 DOI: 10.1111/Ajt.13098 |
0.383 |
|
2014 |
Singh K, Stempora L, Harvey RD, Kirk AD, Larsen CP, Blazar BR, Kean LS. Superiority of rapamycin over tacrolimus in preserving nonhuman primate Treg half-life and phenotype after adoptive transfer. American Journal of Transplantation : Official Journal of the American Society of Transplantation and the American Society of Transplant Surgeons. 14: 2691-703. PMID 25359003 DOI: 10.1111/Ajt.12934 |
0.38 |
|
2014 |
Krummey SM, Cheeseman JA, Conger JA, Jang PS, Mehta AK, Kirk AD, Larsen CP, Ford ML. High CTLA-4 expression on Th17 cells results in increased sensitivity to CTLA-4 coinhibition and resistance to belatacept. American Journal of Transplantation : Official Journal of the American Society of Transplantation and the American Society of Transplant Surgeons. 14: 607-14. PMID 24730049 DOI: 10.1111/Ajt.12600 |
0.506 |
|
2014 |
Kirk AD, Guasch A, Xu H, Cheeseman J, Mead SI, Ghali A, Mehta AK, Wu D, Gebel H, Bray R, Horan J, Kean LS, Larsen CP, Pearson TC. Renal transplantation using belatacept without maintenance steroids or calcineurin inhibitors. American Journal of Transplantation : Official Journal of the American Society of Transplantation and the American Society of Transplant Surgeons. 14: 1142-51. PMID 24684552 DOI: 10.1111/Ajt.12712 |
0.414 |
|
2014 |
Wakwe W, Breeden C, Leopardi F, Farris A, Song M, Strobert E, Jenkins J, Price K, Nadler S, Larsen C, Adams A. Pre-Clinical Evaluation of a Novel Domain Antibody Targeting CD154 in a Non-Human Primate Transplant Model. Transplantation. 98: 680-681. DOI: 10.1097/00007890-201407151-02310 |
0.642 |
|
2014 |
Muehlbacher F, Durrbach A, Florman S, Pestana MJ, Harler M, Larsen C. Outcomes at 3-Years in EBV+ Recipients of Deceased Donor Kidneys From Two Randomized Trials (BENEFIT and BENEFIT EXT) Comparing Belatacept vs Cyclosporine.: Abstract# A196 Transplantation. 98: 435. DOI: 10.1097/00007890-201407151-01513 |
0.329 |
|
2014 |
Krummey S, Gaville C, Cheeseman J, Conger J, Jang P, Suchard S, Boise L, Nadler S, Kirk A, Larsen C, Ford M. Investigating The Functional Role of CD28 On Belatacept-Resistant Human TH17 Memory Cells. Transplantation. 98: 312. DOI: 10.1097/00007890-201407151-00987 |
0.386 |
|
2014 |
Anderson D, Lo D, Strobert E, Kachlany S, Larsen C, Kirk A. Leukotoxin Selectively Kills NK and Effector Memory T Cells. Transplantation. 98: 288. DOI: 10.1097/00007890-201407151-00895 |
0.322 |
|
2014 |
Charpentier B, Larsen C, Grinyo J, Muehlbacher F, Blancho G, Grannas G, Jones-Burton C, Vincenti F. Final Results From the Long-Term Extension (LTE) of the Belatacept Phase 2 Study in Kidney Transplantation.: Abstract# 2164 Transplantation. 98: 117. DOI: 10.1097/00007890-201407151-00359 |
0.387 |
|
2014 |
Bray R, Gebel H, Brannon P, Ganguly B, Townsend R, Meier-Kriesche U, Harler M, Larsen C. Evaluation of Donor-Specific Antibodies Through 5 Years With Belatacept in BENEFIT and BENEFIT-EXT.: Abstract# 2163 Transplantation. 98: 117. DOI: 10.1097/00007890-201407151-00358 |
0.314 |
|
2014 |
Krummey S, Martinez R, Liu D, Wagener M, Kohlmeier J, Evavold B, Larsen C, Ford M. Low Affinity CD8+ CD45RBhigh TNF-Producing TCM Are Potently Alloreactive Against High Affinity Antigen in a Model of T Cell Receptor Cross-Reactive Heterologous Immunity. Transplantation. 98: 33. DOI: 10.1097/00007890-201407151-00105 |
0.43 |
|
2014 |
Ricordi C, Hering B, Bridges N, Eggerman T, Naji A, Posselt A, Stock P, Kaufman D, Larsen C, Turgeon N, Oberholzer J, Barbaro B, Korsgren O, Markmann J, Alejandro R, et al. Completion of the first FDA phase 3 multicenter trial of Islet transplantation in type 1 diabetes by the NIH CIT consortium Cytotherapy. 16: S14. DOI: 10.1016/J.Jcyt.2014.01.034 |
0.337 |
|
2013 |
Koura DT, Horan JT, Langston AA, Qayed M, Mehta A, Khoury HJ, Harvey RD, Suessmuth Y, Couture C, Carr J, Grizzle A, Johnson HR, Cheeseman JA, Conger JA, Robertson J, ... ... Larsen CP, et al. In vivo T cell costimulation blockade with abatacept for acute graft-versus-host disease prevention: a first-in-disease trial. Biology of Blood and Marrow Transplantation : Journal of the American Society For Blood and Marrow Transplantation. 19: 1638-49. PMID 24047754 DOI: 10.1016/J.Bbmt.2013.09.003 |
0.539 |
|
2013 |
Rostaing L, Vincenti F, Grinyó J, Rice KM, Bresnahan B, Steinberg S, Gang S, Gaite LE, Moal MC, Mondragón-Ramirez GA, Kothari J, Pupim L, Larsen CP. Long-term belatacept exposure maintains efficacy and safety at 5 years: results from the long-term extension of the BENEFIT study. American Journal of Transplantation : Official Journal of the American Society of Transplantation and the American Society of Transplant Surgeons. 13: 2875-83. PMID 24047110 DOI: 10.1111/Ajt.12460 |
0.337 |
|
2013 |
Pinelli DF, Wagener ME, Liu D, Yamniuk A, Tamura J, Grant S, Larsen CP, Suri A, Nadler SG, Ford ML. An anti-CD154 domain antibody prolongs graft survival and induces Foxp3(+) iTreg in the absence and presence of CTLA-4 Ig. American Journal of Transplantation : Official Journal of the American Society of Transplantation and the American Society of Transplant Surgeons. 13: 3021-30. PMID 24007441 DOI: 10.1111/Ajt.12417 |
0.466 |
|
2013 |
Beus JM, Hashmi SS, Selvaraj SA, Duan D, Stempora LL, Monday SA, Cheeseman JA, Hamby KM, Speck SH, Larsen CP, Kirk AD, Kean LS. Heterologous immunity triggered by a single, latent virus in Mus musculus: combined costimulation- and adhesion- blockade decrease rejection. Plos One. 8: e71221. PMID 23940724 DOI: 10.1371/Journal.Pone.0071221 |
0.48 |
|
2013 |
Lo DJ, Anderson DJ, Weaver TA, Leopardi F, Song M, Farris AB, Strobert EA, Jenkins J, Turgeon NA, Mehta AK, Larsen CP, Kirk AD. Belatacept and sirolimus prolong nonhuman primate renal allograft survival without a requirement for memory T cell depletion. American Journal of Transplantation : Official Journal of the American Society of Transplantation and the American Society of Transplant Surgeons. 13: 320-8. PMID 23311611 DOI: 10.1111/J.1600-6143.2012.04342.X |
0.529 |
|
2013 |
Lowe MC, Badell IR, Turner AP, Thompson PW, Leopardi FV, Strobert EA, Larsen CP, Kirk AD. Belatacept and sirolimus prolong nonhuman primate islet allograft survival: adverse consequences of concomitant alefacept therapy. American Journal of Transplantation : Official Journal of the American Society of Transplantation and the American Society of Transplant Surgeons. 13: 312-9. PMID 23279640 DOI: 10.1111/J.1600-6143.2012.04341.X |
0.486 |
|
2013 |
Rigby MR, Trexler A, Duan D, Kean L, Larsen CP. Differential Impact of Costimulation Blockade on Antigen-Activation of Foxp3-Positive and Negative T Cells in A Model of Type 1 Diabetes Journal of Diabetes & Metabolism. 2013: 1-11. DOI: 10.4172/2155-6156.1000246 |
0.481 |
|
2013 |
Singh K, Stempora L, Kirk AD, Larsen CP, Blazar BR, Kean LS. Rapamycin Rescues The Rapid Disappearance and Loss Of Phenotypic Integrity Of Autologous, Ex-Vivo Expanded Rhesus Macaque Natural Regulatory T Cells After Adoptive Transfer Blood. 122: 895-895. DOI: 10.1182/Blood.V122.21.895.895 |
0.46 |
|
2013 |
Safley S, Gordon K, Barber G, Holdcraft R, Turgeon N, Larsen C, Gazda L, Weber C. Human and Porcine Islet Transplants in a New Double Capsule Journal of Surgical Research. 179: 264-265. DOI: 10.1016/J.Jss.2012.10.506 |
0.417 |
|
2012 |
Lowe M, Badell IR, Thompson P, Martin B, Leopardi F, Strobert E, Price AA, Abdulkerim HS, Wang R, Iwakoshi NN, Adams AB, Kirk AD, Larsen CP, Reimann KA. A novel monoclonal antibody to CD40 prolongs islet allograft survival. American Journal of Transplantation : Official Journal of the American Society of Transplantation and the American Society of Transplant Surgeons. 12: 2079-87. PMID 22845909 DOI: 10.1111/J.1600-6143.2012.04054.X |
0.686 |
|
2012 |
Barton FB, Rickels MR, Alejandro R, Hering BJ, Wease S, Naziruddin B, Oberholzer J, Odorico JS, Garfinkel MR, Levy M, Pattou F, Berney T, Secchi A, Messinger S, Senior PA, ... ... Larsen C, et al. Improvement in outcomes of clinical islet transplantation: 1999-2010. Diabetes Care. 35: 1436-45. PMID 22723582 DOI: 10.2337/Dc12-0063 |
0.417 |
|
2012 |
Ramakrishnan SK, Page A, Farris AB, Singh K, Leopardi F, Hamby K, Sen S, Polnett A, Deane T, Song M, Stempora L, Strobert E, Kirk AD, Larsen CP, Kean LS. Evidence for kidney rejection after combined bone marrow and renal transplantation despite ongoing whole-blood chimerism in rhesus macaques. American Journal of Transplantation : Official Journal of the American Society of Transplantation and the American Society of Transplant Surgeons. 12: 1755-64. PMID 22642491 DOI: 10.1111/J.1600-6143.2012.04045.X |
0.557 |
|
2012 |
Thompson P, Badell IR, Lowe M, Turner A, Cano J, Avila J, Azimzadeh A, Cheng X, Pierson RN, Johnson B, Robertson J, Song M, Leopardi F, Strobert E, Korbutt G, ... ... Larsen CP, et al. Alternative immunomodulatory strategies for xenotransplantation: CD40/154 pathway-sparing regimens promote xenograft survival. American Journal of Transplantation : Official Journal of the American Society of Transplantation and the American Society of Transplant Surgeons. 12: 1765-75. PMID 22458586 DOI: 10.1111/J.1600-6143.2012.04031.X |
0.51 |
|
2012 |
Badell IR, Russell MC, Cardona K, Shaffer VO, Turner AP, Avila JG, Cano JA, Leopardi FV, Song M, Strobert EA, Ford ML, Pearson TC, Kirk AD, Larsen CP. CTLA4Ig prevents alloantibody formation following nonhuman primate islet transplantation using the CD40-specific antibody 3A8. American Journal of Transplantation : Official Journal of the American Society of Transplantation and the American Society of Transplant Surgeons. 12: 1918-23. PMID 22458552 DOI: 10.1111/J.1600-6143.2012.04029.X |
0.538 |
|
2012 |
Singh K, Kozyr N, Stempora L, Kirk AD, Larsen CP, Blazar BR, Kean LS. Regulatory T cells exhibit decreased proliferation but enhanced suppression after pulsing with sirolimus American Journal of Transplantation. 12: 1441-1457. PMID 22300641 DOI: 10.1111/J.1600-6143.2011.03963.X |
0.527 |
|
2012 |
Kean LS, Singh K, Blazar BR, Larsen CP. Nonhuman primate transplant models finally evolve: Detailed immunogenetic analysis creates new models and strengthens the old American Journal of Transplantation. 12: 812-819. PMID 22177005 DOI: 10.1111/J.1600-6143.2011.03873.X |
0.463 |
|
2012 |
Neujahr DC, Perez SD, Mohammed A, Ulukpo O, Lawrence EC, Fernandez F, Pickens A, Force SD, Song M, Larsen CP, Kirk AD. Cumulative exposure to gamma interferon-dependent chemokines CXCL9 and CXCL10 correlates with worse outcome after lung transplant. American Journal of Transplantation : Official Journal of the American Society of Transplantation and the American Society of Transplant Surgeons. 12: 438-46. PMID 22151926 DOI: 10.1111/J.1600-6143.2011.03857.X |
0.365 |
|
2012 |
Vincenti F, Larsen CP, Alberu J, Bresnahan B, Garcia VD, Kothari J, Lang P, Urrea EM, Massari P, Mondragon-Ramirez G, Reyes-Acevedo R, Rice K, Rostaing L, Steinberg S, Xing J, et al. Three-year outcomes from BENEFIT, a randomized, active-controlled, parallel-group study in adult kidney transplant recipients. American Journal of Transplantation : Official Journal of the American Society of Transplantation and the American Society of Transplant Surgeons. 12: 210-7. PMID 21992533 DOI: 10.1111/J.1600-6143.2011.03785.X |
0.384 |
|
2012 |
Kitchens WH, Haridas D, Wagener ME, Song M, Kirk AD, Larsen CP, Ford ML. Integrin antagonists prevent costimulatory blockade-resistant transplant rejection by CD8(+) memory T cells. American Journal of Transplantation : Official Journal of the American Society of Transplantation and the American Society of Transplant Surgeons. 12: 69-80. PMID 21942986 DOI: 10.1111/J.1600-6143.2011.03762.X |
0.514 |
|
2012 |
Badell IR, Thompson PW, Turner AP, Russell MC, Avila JG, Cano JA, Robertson JM, Leopardi FV, Strobert EA, Iwakoshi NN, Reimann KA, Ford ML, Kirk AD, Larsen CP. Nondepleting anti-CD40-based therapy prolongs allograft survival in nonhuman primates. American Journal of Transplantation : Official Journal of the American Society of Transplantation and the American Society of Transplant Surgeons. 12: 126-35. PMID 21920020 DOI: 10.1111/J.1600-6143.2011.03736.X |
0.526 |
|
2012 |
Lowe M, Martin B, Leopardi F, Song M, Strobert E, Kirk AD, Kean L, Larsen CP. Bone Marrow Cavity Is a Feasible Site for Islet Transplantation in Nonhuman Primates: 841 Transplantation. 94: 161. DOI: 10.1097/00007890-201211271-00298 |
0.366 |
|
2012 |
Singh K, Stempora L, Kirk AD, Larsen CP, Blazar BB, Kean LS. Rhesus Macaque Natural CD4 Regulatory T Cells Exhibit Decreased Proliferation But Enhanced Suppression After Pulsing with Sirolimus Biology of Blood and Marrow Transplantation. 18. DOI: 10.1016/J.Bbmt.2011.12.523 |
0.446 |
|
2011 |
Mohammed A, Ulukpo O, Lawrence EC, Fernandez F, Pickens A, Gal AA, Force SD, Easley KC, Larsen CP, Kirk AD, Neujahr DC. Cumulative exposure to CD8+ granzyme Bhi T cells is associated with reduced lung function early after lung transplantation. Transplantation Proceedings. 43: 3892-8. PMID 22172867 DOI: 10.1016/j.transproceed.2011.09.072 |
0.327 |
|
2011 |
Ferrer IR, Wagener ME, Song M, Kirk AD, Larsen CP, Ford ML. Antigen-specific induced Foxp3+ regulatory T cells are generated following CD40/CD154 blockade. Proceedings of the National Academy of Sciences of the United States of America. 108: 20701-6. PMID 22143783 DOI: 10.1073/Pnas.1105500108 |
0.847 |
|
2011 |
Reisman NM, Floyd TL, Wagener ME, Kirk AD, Larsen CP, Ford ML. LFA-1 blockade induces effector and regulatory T-cell enrichment in lymph nodes and synergizes with CTLA-4Ig to inhibit effector function. Blood. 118: 5851-61. PMID 21972294 DOI: 10.1182/Blood-2011-04-347252 |
0.477 |
|
2011 |
Page A, Srinivasan S, Singh K, Russell M, Hamby K, Deane T, Sen S, Stempora L, Leopardi F, Price AA, Strobert E, Reimann KA, Kirk AD, Larsen CP, Kean LS. CD40 blockade combines with CTLA4Ig and sirolimus to produce mixed chimerism in an MHC-defined rhesus macaque transplant model. American Journal of Transplantation : Official Journal of the American Society of Transplantation and the American Society of Transplant Surgeons. 12: 115-25. PMID 21929643 DOI: 10.1111/J.1600-6143.2011.03737.X |
0.504 |
|
2011 |
Thompson P, Badell IR, Lowe M, Cano J, Song M, Leopardi F, Avila J, Ruhil R, Strobert E, Korbutt G, Rayat G, Rajotte R, Iwakoshi N, Larsen CP, Kirk AD. Islet xenotransplantation using gal-deficient neonatal donors improves engraftment and function. American Journal of Transplantation : Official Journal of the American Society of Transplantation and the American Society of Transplant Surgeons. 11: 2593-602. PMID 21883917 DOI: 10.1111/J.1600-6143.2011.03720.X |
0.477 |
|
2011 |
Ford ML, Larsen CP. Transplantation tolerance: memories that haunt us. Science Translational Medicine. 3: 86ps22. PMID 21653828 DOI: 10.1126/Scitranslmed.3002504 |
0.496 |
|
2011 |
Thompson P, Cardona K, Russell M, Badell IR, Shaffer V, Korbutt G, Rayat GR, Cano J, Song M, Jiang W, Strobert E, Rajotte R, Pearson T, Kirk AD, Larsen CP. CD40-specific costimulation blockade enhances neonatal porcine islet survival in nonhuman primates. American Journal of Transplantation : Official Journal of the American Society of Transplantation and the American Society of Transplant Surgeons. 11: 947-57. PMID 21521467 DOI: 10.1111/J.1600-6143.2011.03509.X |
0.507 |
|
2011 |
Neujahr DC, Larsen CP. Regulatory T cells in lung transplantation--an emerging concept. Seminars in Immunopathology. 33: 117-27. PMID 21424593 DOI: 10.1007/S00281-011-0253-0 |
0.46 |
|
2011 |
Kitchens WH, Larsen CP, Ford ML. Integrin antagonists for transplant immunosuppression: panacea or peril? Immunotherapy. 3: 305-7. PMID 21395371 DOI: 10.2217/Imt.10.113 |
0.51 |
|
2011 |
Vanrenterghem Y, Bresnahan B, Campistol J, Durrbach A, Grinyó J, Neumayer HH, Lang P, Larsen CP, Mancilla-Urrea E, Pestana JM, Block A, Duan T, Glicklich A, Gujrathi S, Vincenti F. Belatacept-based regimens are associated with improved cardiovascular and metabolic risk factors compared with cyclosporine in kidney transplant recipients (BENEFIT and BENEFIT-EXT studies). Transplantation. 91: 976-83. PMID 21372756 DOI: 10.1097/Tp.0B013E31820C10Eb |
0.406 |
|
2011 |
Turner AP, Shaffer VO, Araki K, Martens C, Turner PL, Gangappa S, Ford ML, Ahmed R, Kirk AD, Larsen CP. Sirolimus enhances the magnitude and quality of viral-specific CD8+ T-cell responses to vaccinia virus vaccination in rhesus macaques. American Journal of Transplantation : Official Journal of the American Society of Transplantation and the American Society of Transplant Surgeons. 11: 613-8. PMID 21342450 DOI: 10.1111/J.1600-6143.2010.03407.X |
0.459 |
|
2011 |
Larsen CP, Elwood ET, Alexander DZ, Ritchie SC, Hendrix R, Tucker-Burden C, Cho HR, Aruffo A, Hollenbaugh D, Linsley PS, Winn KJ, Pearson TC. Pillars article: long-term acceptance of skin and cardiac allografts after blocking CD40 and CD28 pathways. Nature. 1996. 381: 434-438. 1996. Journal of Immunology (Baltimore, Md. : 1950). 186: 2693-7. PMID 21325218 |
0.314 |
|
2011 |
Floyd TL, Koehn BH, Kitchens WH, Robertson JM, Cheeseman JA, Stempora L, Larsen CP, Ford ML. Limiting the amount and duration of antigen exposure during priming increases memory T cell requirement for costimulation during recall. Journal of Immunology (Baltimore, Md. : 1950). 186: 2033-41. PMID 21257960 DOI: 10.4049/Jimmunol.1003015 |
0.8 |
|
2011 |
Ford ML, Stempora LL, Larsen CP. CD28 blockade induces division-dependent downregulation of interleukin-2 receptor alpha. Transplant Immunology. 24: 94-9. PMID 21073953 DOI: 10.1016/J.Trim.2010.11.002 |
0.549 |
|
2011 |
Lo DJ, Weaver TA, Stempora L, Mehta AK, Ford ML, Larsen CP, Kirk AD. Selective targeting of human alloresponsive CD8+ effector memory T cells based on CD2 expression. American Journal of Transplantation : Official Journal of the American Society of Transplantation and the American Society of Transplant Surgeons. 11: 22-33. PMID 21070604 DOI: 10.1111/J.1600-6143.2010.03317.X |
0.516 |
|
2011 |
Singh K, Kozyr N, Stempora L, Kirk AD, Larsen CP, Blazar BR, Kean LS. Sirolimus Inhibits Proliferation but Enhances Suppressive Activity of Rhesus Macaque Natural CD4 Regulatory T Cells Blood. 118: 1008-1008. DOI: 10.1182/Blood.V118.21.1008.1008 |
0.498 |
|
2011 |
Bendorf A, Kerridge I, Pussell B, Donadio C, Hesham A, Grassi G, Kanaki A, Barsotti M, Hertig A, Dubois-Xu Y, Buob D, Noel C, Rondeau E, Hazzan M, Dahle DO, ... ... Larsen C, et al. Transplantation / Clinical studies Clinical Kidney Journal. 4: 4.s2.18-4.s2.18. DOI: 10.1093/Ndtplus/4.S2.18 |
0.42 |
|
2010 |
Badell IR, Russell MC, Thompson PW, Turner AP, Weaver TA, Robertson JM, Avila JG, Cano JA, Johnson BE, Song M, Leopardi FV, Swygert S, Strobert EA, Ford ML, Kirk AD, ... Larsen CP, et al. LFA-1-specific therapy prolongs allograft survival in rhesus macaques. The Journal of Clinical Investigation. 120: 4520-31. PMID 21099108 DOI: 10.1172/Jci43895 |
0.561 |
|
2010 |
Grinyó J, Charpentier B, Pestana JM, Vanrenterghem Y, Vincenti F, Reyes-Acevedo R, Apanovitch AM, Gujrathi S, Agarwal M, Thomas D, Larsen CP. An integrated safety profile analysis of belatacept in kidney transplant recipients. Transplantation. 90: 1521-7. PMID 21088650 DOI: 10.1097/Tp.0B013E3182007B95 |
0.405 |
|
2010 |
Larsen CP, Grinyó J, Medina-Pestana J, Vanrenterghem Y, Vincenti F, Breshahan B, Campistol JM, Florman S, Rial Mdel C, Kamar N, Block A, Di Russo G, Lin CS, Garg P, Charpentier B. Belatacept-based regimens versus a cyclosporine A-based regimen in kidney transplant recipients: 2-year results from the BENEFIT and BENEFIT-EXT studies. Transplantation. 90: 1528-35. PMID 21076381 DOI: 10.1097/Tp.0B013E3181Ff87Cd |
0.407 |
|
2010 |
Araki K, Gangappa S, Dillehay DL, Rouse BT, Larsen CP, Ahmed R. Pathogenic virus-specific T cells cause disease during treatment with the calcineurin inhibitor FK506: implications for transplantation. The Journal of Experimental Medicine. 207: 2355-67. PMID 20921283 DOI: 10.1084/Jem.20100124 |
0.457 |
|
2010 |
Turgeon NA, Avila JG, Cano JA, Hutchinson JJ, Badell IR, Page AJ, Adams AB, Sears MH, Bowen PH, Kirk AD, Pearson TC, Larsen CP. Experience with a novel efalizumab-based immunosuppressive regimen to facilitate single donor islet cell transplantation. American Journal of Transplantation : Official Journal of the American Society of Transplantation and the American Society of Transplant Surgeons. 10: 2082-91. PMID 20883542 DOI: 10.1111/J.1600-6143.2010.03212.X |
0.622 |
|
2010 |
Larsen CP, Page A, Linzie KH, Russell MC, Deane T, Stempora L, Strobert E, Penedo MCT, Ward T, Wiseman R, O'Connor D, Miller W, Sen S, Singh K, Kean LS. An MHC-defined primate model reveals significant rejection of bone marrow after mixed-chimerism induction despite full MHC matching American Journal of Transplantation. 10: 2396-2409. PMID 20849552 DOI: 10.1111/J.1600-6143.2010.03272.X |
0.582 |
|
2010 |
Miller WP, Srinivasan S, Panoskaltsis-Mortari A, Singh K, Sen S, Hamby K, Deane T, Stempora L, Beus J, Turner A, Wheeler C, Anderson DC, Sharma P, Garcia A, Strobert E, ... ... Larsen CP, et al. GVHD after haploidentical transplantation: a novel, MHC-defined rhesus macaque model identifies CD28- CD8+ T cells as a reservoir of breakthrough T-cell proliferation during costimulation blockade and sirolimus-based immunosuppression. Blood. 116: 5403-18. PMID 20833977 DOI: 10.1182/Blood-2010-06-289272 |
0.548 |
|
2010 |
Vincenti F, Blancho G, Durrbach A, Friend P, Grinyo J, Halloran PF, Klempnauer J, Lang P, Larsen CP, Mühlbacher F, Nashan B, Soulillou JP, Vanrenterghem Y, Wekerle T, Agarwal M, et al. Five-year safety and efficacy of belatacept in renal transplantation. Journal of the American Society of Nephrology : Jasn. 21: 1587-96. PMID 20634298 DOI: 10.1681/Asn.2009111109 |
0.398 |
|
2010 |
Ferrer IR, Wagener ME, Robertson JM, Turner AP, Araki K, Ahmed R, Kirk AD, Larsen CP, Ford ML. Cutting edge: Rapamycin augments pathogen-specific but not graft-reactive CD8+ T cell responses. Journal of Immunology (Baltimore, Md. : 1950). 185: 2004-8. PMID 20631309 DOI: 10.4049/Jimmunol.1001176 |
0.822 |
|
2010 |
Ford ML, Larsen CP. Overcoming the memory barrier in tolerance induction: molecular mimicry and functional heterogeneity among pathogen-specific T-cell populations. Current Opinion in Organ Transplantation. 15: 405-10. PMID 20616729 DOI: 10.1097/Mot.0B013E32833B7916 |
0.352 |
|
2010 |
Neujahr DC, Mohammed A, Ulukpo O, Force SD, Ramirez AM, Pelaez A, Lawrence EC, Larsen CP, Kirk AD. Surgical correction of gastroesophageal reflux in lung transplant patients is associated with decreased effector CD8 cells in lung lavages: a case series. Chest. 138: 937-43. PMID 20522573 DOI: 10.1378/Chest.09-2888 |
0.423 |
|
2010 |
Vincenti F, Charpentier B, Vanrenterghem Y, Rostaing L, Bresnahan B, Darji P, Massari P, Mondragon-Ramirez GA, Agarwal M, Di Russo G, Lin CS, Garg P, Larsen CP. A phase III study of belatacept-based immunosuppression regimens versus cyclosporine in renal transplant recipients (BENEFIT study). American Journal of Transplantation : Official Journal of the American Society of Transplantation and the American Society of Transplant Surgeons. 10: 535-46. PMID 20415897 DOI: 10.1111/J.1600-6143.2009.03005.X |
0.411 |
|
2010 |
Floyd TL, Orr SB, Coley SM, Hanna SS, Wagener ME, Kirk AD, Larsen CP, Ford ML. High-frequency alloreactive T cells augment effector function of low-frequency CD8+ T-cell responses under CD28/CD154 blockade. Transplantation. 89: 1208-17. PMID 20407401 DOI: 10.1097/Tp.0B013E3181Df53Dc |
0.764 |
|
2010 |
Radziewicz H, Ibegbu CC, Hon H, Bédard N, Bruneau J, Workowski KA, Knechtle SJ, Kirk AD, Larsen CP, Shoukry NH, Grakoui A. Transient CD86 expression on hepatitis C virus-specific CD8+ T cells in acute infection is linked to sufficient IL-2 signaling. Journal of Immunology (Baltimore, Md. : 1950). 184: 2410-22. PMID 20100932 DOI: 10.4049/Jimmunol.0902994 |
0.415 |
|
2010 |
Beus J, Hamby K, Kirk AD, Larsen CP, Speck SH, Kean L. Identification of a Costimulation Blockade Resistant Mechanism of Bone Marrow Allograft Rejection Induced by Infection with a Murine EBV Homologue. Blood. 116: 1461-1461. DOI: 10.1182/Blood.V116.21.1461.1461 |
0.534 |
|
2010 |
Vincenti F, Grinyo J, Larsen C, Pestana JOM, Vanrenterghem Y, Duan T, Agarwal M, Charpentier B. Benefit-Risk Profile Of The Belatacept Li Regimen At 2 Years In Ebv(+) Kidney Transplant Recipients: 3370 Transplantation. 90: 649. DOI: 10.1097/00007890-201007272-01238 |
0.424 |
|
2010 |
Florman S, Durrbach A, Larsen C, Pestana JM, Vanrenterghem Y, Vincenti F, Block A, Garg P, Copley B, Duan T, Grinyó JM. Outcomes As A Function Of Donor Criteria From A Phase Iii Study Of Belatacept Vs Cyclosporine In Kidney Transplantation (Benefit-Ext): 1773 Transplantation. 90: 342. DOI: 10.1097/00007890-201007272-00641 |
0.406 |
|
2010 |
Singh K, Srinivasan S, Page A, Larsen C, Kean LS. THE PITFALLS OF MYELOID-ONLY MIXED-CHIMERISM: LACK OF T CELL CHIMERISM CORRELATES WITH TRANSPLANT REJECTION AFTER IMMUNOSUPPRESSION WITHDRAWAL IN A NOVEL, MHC-DEFINED PRIMATE MODEL. Transplantation Journal. 90: 234. DOI: 10.1097/00007890-201007272-00444 |
0.513 |
|
2010 |
Vincenti F, Grinyó JM, Charpentier B, Pestana JOM, Rostaing L, Vanrenterghem Y, Lin C, Russo GD, Larsen C. Outcomes As A Function Of Donor:Recipient Characteristics From A Phase Iii Study Of Belatacept Vs Cyclosporine In Kidney Transplantation (Benefit): 2857 Transplantation. 90: 175. DOI: 10.1097/00007890-201007272-00339 |
0.422 |
|
2010 |
Larsen C, Grinyó JM, Charpentier B, Pestana JOM, Kamar N, Vanrenterghem Y, Lin C, Russo GD, Garg P, Vincenti F. Belatacept Vs Cyclosporine In Kidney Transplant Recipients: Two-Year Outcomes From The Benefit Study: 1374 Transplantation. 90: 158. DOI: 10.1097/00007890-201007272-00304 |
0.421 |
|
2010 |
Durrbach A, Larsen C, Pestana JOM, Vanrenterghem Y, Vincenti F, Florman S, Xing J, Block A, Garg P, Grinyó JM. Belatacept Vs Cyclosporine In Ecd Kidney Transplants: Two-Year Outcomes From The Benefit-Ext Study: 1394 Transplantation. 90: 157. DOI: 10.1097/00007890-201007272-00303 |
0.403 |
|
2010 |
Grinyo J, Charpentier B, Pestana JOM, Vanrenterghem Y, Vincenti F, Shi R, Agarwal M, Thomas D, Larsen C. Safety Profile Of Belatacept In Kidney Transplant Recipients From A Pooled Analysis Of Phase Ii And Phase Iii Studies: 1417 Transplantation. 90: 156. DOI: 10.1097/00007890-201007272-00300 |
0.351 |
|
2010 |
Beus J, Selvaraj S, Gangappa S, Kirk A, Larsen C, Speck S, Kean LS. SEPARATING ANTIVIRAL RESPONSE FROM HETEROLOGOUS ALLOREACTIVITY: Vβ4 CD8 T CELLS MAY NOT DIRECTLY CAUSE ALLOGRAFT REJECTION IN LATENT MHV68 INFECTION: 2605 Transplantation. 90: 1. DOI: 10.1097/00007890-201007272-00002 |
0.507 |
|
2010 |
Shahnavaz N, Mwangi SM, Usta Y, Joseph I, Avila J, Cano J, Chetty VK, Larsen CP, Srinivasan S. T1942 Glial Cell Line Derived Neurotrophic Factor Enhances Human Islet Pre- And Post-Transplantation Survival Gastroenterology. 138. DOI: 10.1016/S0016-5085(10)62819-3 |
0.451 |
|
2010 |
Neujahr D, Mohammed A, Ulukpo O, Pelaez A, Ramirez A, Lawrence E, Force S, Gal A, Larsen C, Kirk A. 150: Flow Cytometric Parameters of CD8 Lavage Cells in Detection of Acute Cellular Rejection in Lung Transplant The Journal of Heart and Lung Transplantation. 29: S55-S55. DOI: 10.1016/J.Healun.2009.11.159 |
0.472 |
|
2009 |
Neujahr DC, Cardona AC, Ulukpo O, Rigby M, Pelaez A, Ramirez A, Gal AA, Force SD, Lawrence EC, Kirk AD, Larsen CP. Dynamics of human regulatory T cells in lung lavages of lung transplant recipients. Transplantation. 88: 521-7. PMID 19696635 DOI: 10.1097/Tp.0B013E3181B0E719 |
0.453 |
|
2009 |
Gilson CR, Milas Z, Gangappa S, Hollenbaugh D, Pearson TC, Ford ML, Larsen CP. Anti-CD40 monoclonal antibody synergizes with CTLA4-Ig in promoting long-term graft survival in murine models of transplantation. Journal of Immunology (Baltimore, Md. : 1950). 183: 1625-35. PMID 19592649 DOI: 10.4049/Jimmunol.0900339 |
0.472 |
|
2009 |
Weaver TA, Charafeddine AH, Agarwal A, Turner AP, Russell M, Leopardi FV, Kampen RL, Stempora L, Song M, Larsen CP, Kirk AD. Alefacept promotes co-stimulation blockade based allograft survival in nonhuman primates. Nature Medicine. 15: 746-9. PMID 19584865 DOI: 10.1038/Nm.1993 |
0.527 |
|
2009 |
Araki K, Turner AP, Shaffer VO, Gangappa S, Keller SA, Bachmann MF, Larsen CP, Ahmed R. mTOR regulates memory CD8 T-cell differentiation. Nature. 460: 108-12. PMID 19543266 DOI: 10.1038/Nature08155 |
0.4 |
|
2009 |
Heffron TG, Rodriguez J, Fasola CG, Casper K, Pillen T, Smallwood G, Warshaw B, Romero R, Larsen C. Successful outcome after early combined liver and en bloc-kidney transplant in an infant with primary hyperoxaluria type 1: a case report. Pediatric Transplantation. 13: 940-942. PMID 19496983 DOI: 10.1111/J.1399-3046.2009.01189.X |
0.383 |
|
2009 |
Ford ML, Larsen CP. Translating costimulation blockade to the clinic: lessons learned from three pathways. Immunological Reviews. 229: 294-306. PMID 19426229 DOI: 10.1111/J.1600-065X.2009.00776.X |
0.552 |
|
2009 |
Ford ML, Kirk AD, Larsen CP. Donor-reactive T-cell stimulation history and precursor frequency: barriers to tolerance induction. Transplantation. 87: S69-74. PMID 19424013 DOI: 10.1097/Tp.0B013E3181A2A701 |
0.465 |
|
2009 |
Coley SM, Ford ML, Hanna SC, Wagener ME, Kirk AD, Larsen CP. IFN-gamma dictates allograft fate via opposing effects on the graft and on recipient CD8 T cell responses. Journal of Immunology (Baltimore, Md. : 1950). 182: 225-33. PMID 19109153 DOI: 10.4049/Jimmunol.182.1.225 |
0.775 |
|
2009 |
Larsen C, Charpentier B, Grinyo JM, Medina-Pestana JD, Vanrenterghem Y, Vincenti F, Thomas D, Russo GBD, Shirima RR. 3-Year Safety Profile of Belatacept in Kidney Transplant Recipients from the BENEFIT and BENEFIT-EXT Studies Transplant International. 22: 90-90. DOI: 10.1111/J.1432-2277.2011.01346.X |
0.426 |
|
2009 |
Vincenti F, Grinyo JM, Charpentier B, Medina-Pestana JD, Rostaing L, Vanrenterghem Y, Russo GBD, Garg P, Lin CS, Larsen C. Primary Outcomes from a Randomized, Phase III Study of Belatacept vs Cyclosporine in Kidney Transplant Recipients (BENEFIT Study) Transplant International. 22: 89-89. DOI: 10.1111/J.1432-2277.2009.00961.X |
0.4 |
|
2009 |
Durrbach A, Larsen CP, Pestana JOM, Vanrenterghem Y, Vincenti F, Florman S, Block AJ, Garg P, Sen K, Grinyo JM. Primary outcomes from a randomized, Phase III study of belatacept vs cyclosporine in ECD kidney transplants (BENEFIT-EXT Study) Transplant International. 22: 89-89. DOI: 10.1111/J.1432-2277.2009.00960.X |
0.377 |
|
2009 |
Badell IR, Turner AP, Cano JA, Avila JG, Johnson BE, Leopardi FV, Swygert SG, Strobert EA, Kirk AD, Larsen CP. A novel calcineurin inhibitor– and sirolimus-free anti-LFA-1-based therapy enhances allogeneic islet survival and function in nonhuman primates Journal of the American College of Surgeons. 209: S56. DOI: 10.1016/J.Jamcollsurg.2009.06.133 |
0.321 |
|
2009 |
Neujahr D, Pelaez A, Ramirez A, Force S, Lawrence E, Cardona A, Kirk A, Larsen C. 455: Surgical Repair of Gastroesophageal Reflux in Lung Transplant Recipients Is Associated with Decreased Armed Effector T Cells and Increased Exhausted T Cells within the Allograft The Journal of Heart and Lung Transplantation. 28: S224. DOI: 10.1016/J.Healun.2008.11.462 |
0.458 |
|
2009 |
Miller W, Wheeler C, Panoskaltsis-Mortari A, Kirk A, Larsen C, Blazar B, Kean L. Prevention Of Acute GvHD During Haplo-BMT: Evaluating The Efficacy Of T-Cell Costimulation Blockade Using A Novel Rhesus Macaque Transplant Model Biology of Blood and Marrow Transplantation. 15: 114-115. DOI: 10.1016/J.Bbmt.2008.12.354 |
0.482 |
|
2008 |
Koehn BH, Ford ML, Ferrer IR, Borom K, Gangappa S, Kirk AD, Larsen CP. PD-1-dependent mechanisms maintain peripheral tolerance of donor-reactive CD8+ T cells to transplanted tissue. Journal of Immunology (Baltimore, Md. : 1950). 181: 5313-22. PMID 18832687 DOI: 10.4049/Jimmunol.181.8.5313 |
0.821 |
|
2008 |
Kalb B, Martin DR, Salman K, Sharma P, Votaw J, Larsen C. Kidney transplantation: structural and functional evaluation using MR Nephro-Urography. Journal of Magnetic Resonance Imaging : Jmri. 28: 805-22. PMID 18821623 DOI: 10.1002/Jmri.21562 |
0.392 |
|
2008 |
Anderson A, Martens CL, Hendrix R, Stempora LL, Miller WP, Hamby K, Russell M, Strobert E, Blazar BR, Pearson TC, Larsen CP, Kean LS. Expanded nonhuman primate tregs exhibit a unique gene expression signature and potently downregulate alloimmune responses. American Journal of Transplantation : Official Journal of the American Society of Transplantation and the American Society of Transplant Surgeons. 8: 2252-64. PMID 18801023 DOI: 10.1111/J.1600-6143.2008.02376.X |
0.462 |
|
2008 |
Rigby MR, Trexler AM, Pearson TC, Larsen CP. CD28/CD154 blockade prevents autoimmune diabetes by inducing nondeletional tolerance after effector t-cell inhibition and regulatory T-cell expansion. Diabetes. 57: 2672-83. PMID 18492787 DOI: 10.2337/Db07-1712 |
0.46 |
|
2008 |
Ford ML, Wagener ME, Hanna SS, Pearson TC, Kirk AD, Larsen CP. A critical precursor frequency of donor-reactive CD4+ T cell help is required for CD8+ T cell-mediated CD28/CD154-independent rejection. Journal of Immunology (Baltimore, Md. : 1950). 180: 7203-11. PMID 18490719 DOI: 10.4049/Jimmunol.180.11.7203 |
0.545 |
|
2008 |
Gangappa S, Larsen CP. Immunosuppressive protocols for pig-to-human islet transplantation: lessons from pre-clinical non-human primate models. Xenotransplantation. 15: 107-11. PMID 18447881 DOI: 10.1111/J.1399-3089.2008.00464.X |
0.377 |
|
2008 |
Groth CG, Korbutt GS, Hering B, Prabhakaran S, D'Apice AJF, O'Connell PJ, Rajotte RV, Nilsson B, Cowan P, Contreras JL, Eckhoff DE, Bottino R, Cooper DKC, Gangappa S, Larsen C, et al. A consensus document based on the pig-to-man islet transplant summit held in Stockholm, June 4-5, 2007 Xenotransplantation. 15. PMID 18447870 DOI: 10.1111/J.1399-3089.2008.00454_2.X |
0.447 |
|
2008 |
Dobbels F, Moons P, Abraham I, Larsen CP, Dupont L, De Geest S. Measuring symptom experience of side-effects of immunosuppressive drugs: the Modified Transplant Symptom Occurrence and Distress Scale. Transplant International : Official Journal of the European Society For Organ Transplantation. 21: 764-73. PMID 18435683 DOI: 10.1111/J.1432-2277.2008.00674.X |
0.33 |
|
2008 |
Stapler D, Lee ED, Selvaraj SA, Evans AG, Kean LS, Speck SH, Larsen CP, Gangappa S. Expansion of effector memory TCR Vbeta4+ CD8+ T cells is associated with latent infection-mediated resistance to transplantation tolerance. Journal of Immunology (Baltimore, Md. : 1950). 180: 3190-200. PMID 18292543 DOI: 10.4049/Jimmunol.180.5.3190 |
0.515 |
|
2008 |
Gangappa S, Kokko KE, Carlson LM, Gourley T, Newell KA, Pearson TC, Ahmed R, Larsen CP. Immune responsiveness and protective immunity after transplantation. Transplant International : Official Journal of the European Society For Organ Transplantation. 21: 293-303. PMID 18225995 DOI: 10.1111/J.1432-2277.2007.00631.X |
0.32 |
|
2008 |
Emamaullee JA, Merani S, Larsen CP, Shapiro AM. Belatacept and basiliximab diminish human antiporcine xenoreactivity and synergize to inhibit alloimmunity. Transplantation. 85: 118-24. PMID 18192921 DOI: 10.1097/01.Tp.0000296832.92128.94 |
0.391 |
|
2008 |
Agarwal A, Metha A, Turner A, Kokko K, Turgeon N, Tso P, Newell K, Larsen C, Kirk A. Impact Of Rabbit Anti-Thymocyte Globulin Induction Therapy On Reactivation Of Bk Virus In Renal Transplant Recipients: 227 Transplantation. 86: 80. DOI: 10.1097/01.Tp.0000332624.30231.A1 |
0.414 |
|
2008 |
Shen L, Kuppachi S, Agarwal A, Turgeon N, Tso P, Newell K, Pearson T, Larsen C, Kirk A. Influence Of Donor Type On Elderly Kidney Transplant Survival And Allograft Function: 327 Transplantation. 86: 116. DOI: 10.1097/01.Tp.0000332432.68459.98 |
0.455 |
|
2008 |
Kirk A, Charafeddine A, Hamby K, Larsen C, Kean L. DEPLETION OF CD16+ CELLS LEADS TO INCREASED SURVIVAL OF CFSE-LABELED PERIPHERAL BLOOD STEM CELLS IN RHESUS MACAQUES Transplantation. 86: 410. DOI: 10.1097/01.Tp.0000331474.40601.7D |
0.425 |
|
2008 |
Shen L, Agarwal A, Turgeon N, Pearson T, Larsen C, Bray R, Gebel H, Kirk A, Kokko K. Combined Liver-Kidney Transplantation Across A Positive Flow Crossmatch: A Cause For Concern?: 2009 Transplantation. 86: 660. DOI: 10.1097/01.Tp.0000330701.55212.Bf |
0.371 |
|
2008 |
Mulupuri P, Gourley T, Popkowski A, Mehta A, Begley B, Breeden C, Larsen C, Ahmed R. Protective Immunity in Transplant Recipients The Faseb Journal. 22: 532-532. DOI: 10.1096/Fasebj.22.2_Supplement.532 |
0.448 |
|
2007 |
Mueller SN, Matloubian M, Clemens DM, Sharpe AH, Freeman GJ, Gangappa S, Larsen CP, Ahmed R. Viral targeting of fibroblastic reticular cells contributes to immunosuppression and persistence during chronic infection. Proceedings of the National Academy of Sciences of the United States of America. 104: 15430-5. PMID 17878315 DOI: 10.1073/Pnas.0702579104 |
0.338 |
|
2007 |
Cardona K, Milas Z, Strobert E, Cano J, Jiang W, Safley SA, Gangappa S, Hering BJ, Weber CJ, Pearson TC, Larsen CP. Engraftment of adult porcine islet xenografts in diabetic nonhuman primates through targeting of costimulation pathways. American Journal of Transplantation : Official Journal of the American Society of Transplantation and the American Society of Transplant Surgeons. 7: 2260-8. PMID 17845561 DOI: 10.1111/J.1600-6143.2007.01933.X |
0.45 |
|
2007 |
Koehn BH, Williams MA, Borom K, Gangappa S, Pearson TC, Ahmed R, Larsen CP. Fully MHC-disparate mixed hemopoietic chimeras show specific defects in the control of chronic viral infections. Journal of Immunology (Baltimore, Md. : 1950). 179: 2616-26. PMID 17675525 DOI: 10.4049/Jimmunol.179.4.2616 |
0.77 |
|
2007 |
Zahorchak AF, Kean LS, Tokita D, Turnquist HR, Abe M, Finke J, Hamby K, Rigby MR, Larsen CP, Thomson AW. Infusion of stably immature monocyte-derived dendritic cells plus CTLA4Ig modulates alloimmune reactivity in rhesus macaques. Transplantation. 84: 196-206. PMID 17667811 DOI: 10.1097/01.Tp.0000268582.21168.F6 |
0.401 |
|
2007 |
Hamby K, Trexler A, Pearson TC, Larsen CP, Rigby MR, Kean LS. NK cells rapidly reject allogeneic bone marrow in the spleen through a perforin- and Ly49D-dependent, but NKG2D-independent mechanism American Journal of Transplantation. 7: 1884-1896. PMID 17617852 DOI: 10.1111/J.1600-6143.2007.01864.X |
0.421 |
|
2007 |
Newell KA, Larsen CP. Transplantation tolerance. Seminars in Nephrology. 27: 487-97. PMID 17616279 DOI: 10.1016/j.semnephrol.2007.03.008 |
0.348 |
|
2007 |
Ford ML, Wagener ME, Gangappa S, Pearson TC, Larsen CP. Antigenic disparity impacts outcome of agonism but not blockade of costimulatory pathways in experimental transplant models American Journal of Transplantation. 7: 1471-1481. PMID 17511677 DOI: 10.1111/J.1600-6143.2007.01826.X |
0.553 |
|
2007 |
Singh N, Chandler PR, Seki Y, Baban B, Takezaki M, Kahler DJ, Munn DH, Larsen CP, Mellor AL, Iwashima M. Role of CD28 in fatal autoimmune disorder in scurfy mice. Blood. 110: 1199-206. PMID 17463170 DOI: 10.1182/Blood-2006-10-054585 |
0.477 |
|
2007 |
Ford ML, Koehn BH, Wagener ME, Jiang W, Gangappa S, Pearson TC, Larsen CP. Antigen-specific precursor frequency impacts T cell proliferation, differentiation, and requirement for costimulation. The Journal of Experimental Medicine. 204: 299-309. PMID 17261633 DOI: 10.1084/Jem.20062319 |
0.801 |
|
2007 |
Kean LS, Adams AB, Strobert E, Hendrix R, Gangappa S, Jones TR, Shirasugi N, Rigby MR, Hamby K, Jiang J, Bello H, Anderson D, Cardona K, Durham MM, Pearson TC, ... Larsen CP, et al. Induction of chimerism in rhesus macaques through stem cell transplant and costimulation blockade-based immunosuppression American Journal of Transplantation. 7: 320-335. PMID 17241112 DOI: 10.1111/J.1600-6143.2006.01622.X |
0.709 |
|
2007 |
Kean LS, Hamby K, Deane T, Pearson TC, Larsen CP. MHC-Matched Stem Cell Transplantation in Rhesus Macaques Using a Costimulation Blockade-Based Immunomodulation Platform. Blood. 110: 1189-1189. DOI: 10.1182/Blood.V110.11.1189.1189 |
0.549 |
|
2007 |
Cardona K, Strobert E, Rajotte RV, Pearson TC, Larsen CP. (2) Targeting the T-cell costimulation pathways allows long-term survival of neonatal porcine islets in diabetic non-human primates Xenotransplantation. 14: 178-179. DOI: 10.1111/J.1399-3089.2007.00386_4.X |
0.326 |
|
2007 |
Neujahr D, Lawrence E, Pelaez A, Ramirez A, Force S, Gal A, Larsen C. 35: Frequency of FoxP3+ regulatory CD4 cells recovered in bronchoalveolar lavage does not predict acute rejection score The Journal of Heart and Lung Transplantation. 26: S73. DOI: 10.1016/J.Healun.2006.11.049 |
0.524 |
|
2006 |
Li JM, Gorechlad J, Larsen CP, Waller EK. Apoptotic donor leukocytes limit mixed-chimerism induced by CD40-CD154 blockade in allogeneic bone marrow transplantation. Biology of Blood and Marrow Transplantation : Journal of the American Society For Blood and Marrow Transplantation. 12: 1239-49. PMID 17162205 DOI: 10.1016/J.Bbmt.2006.08.038 |
0.589 |
|
2006 |
Vezys V, Masopust D, Kemball CC, Barber DL, O'Mara LA, Larsen CP, Pearson TC, Ahmed R, Lukacher AE. Continuous recruitment of naive T cells contributes to heterogeneity of antiviral CD8 T cells during persistent infection. The Journal of Experimental Medicine. 203: 2263-9. PMID 16966427 DOI: 10.1084/Jem.20060995 |
0.456 |
|
2006 |
Bray RA, Nolen JD, Larsen C, Pearson T, Newell KA, Kokko K, Guasch A, Tso P, Mendel JB, Gebel HM. Transplanting the highly sensitized patient: The emory algorithm. American Journal of Transplantation : Official Journal of the American Society of Transplantation and the American Society of Transplant Surgeons. 6: 2307-15. PMID 16939516 DOI: 10.1111/J.1600-6143.2006.01521.X |
0.438 |
|
2006 |
Newell KA, Larsen CP. Toward transplantation tolerance: a large step on a long road. American Journal of Transplantation : Official Journal of the American Society of Transplantation and the American Society of Transplant Surgeons. 6: 1989-90. PMID 16869804 DOI: 10.1111/j.1600-6143.2006.01481.x |
0.325 |
|
2006 |
Newell KA, Larsen CP. Tolerance assays: measuring the unknown. Transplantation. 81: 1503-9. PMID 16770237 DOI: 10.1097/01.Tp.0000222912.69532.1E |
0.455 |
|
2006 |
Han Lee ED, Kemball CC, Wang J, Dong Y, Stapler DC, Hamby KM, Gangappa S, Newell KA, Pearson TC, Lukacher AE, Larsen CP. A mouse model for polyomavirus-associated nephropathy of kidney transplants. American Journal of Transplantation : Official Journal of the American Society of Transplantation and the American Society of Transplant Surgeons. 6: 913-22. PMID 16611327 DOI: 10.1111/J.1600-6143.2006.01265.X |
0.481 |
|
2006 |
Kean LS, Gangappa S, Pearson TC, Larsen CP. Transplant tolerance in non-human primates: Progress, current challenges and unmet needs American Journal of Transplantation. 6: 884-893. PMID 16611324 DOI: 10.1111/J.1600-6143.2006.01260.X |
0.491 |
|
2006 |
Larsen CP, Knechtle SJ, Adams A, Pearson T, Kirk AD. A new look at blockade of T-cell costimulation: A therapeutic strategy for long-term maintenance immunosuppression American Journal of Transplantation. 6: 876-883. PMID 16611323 DOI: 10.1111/J.1600-6143.2006.01259.X |
0.679 |
|
2006 |
Cardona K, Korbutt GS, Milas Z, Lyon J, Cano J, Jiang W, Bello-Laborn H, Hacquoil B, Strobert E, Gangappa S, Weber CJ, Pearson TC, Rajotte RV, Larsen CP. Long-term survival of neonatal porcine islets in nonhuman primates by targeting costimulation pathways. Nature Medicine. 12: 304-6. PMID 16501570 DOI: 10.1038/Nm1375 |
0.507 |
|
2006 |
Koehn B, Gangappa S, Miller JD, Ahmed R, Larsen CP. Patients, pathogens, and protective immunity: the relevance of virus-induced alloreactivity in transplantation. Journal of Immunology (Baltimore, Md. : 1950). 176: 2691-6. PMID 16493023 DOI: 10.4049/Jimmunol.176.5.2691 |
0.765 |
|
2006 |
Emmanouilidis N, Guo Z, Dong Y, Newton-West M, Adams AB, Lee ED, Wang J, Pearson TC, Larsen CP, Newell KA. Immunosuppressive and trafficking properties of donor splenic and bone marrow dendritic cells. Transplantation. 81: 455-62. PMID 16477234 DOI: 10.1097/01.Tp.0000195779.01491.4E |
0.635 |
|
2006 |
Kean LS, Hamby K, Koehn B, Lee E, Coley S, Stempora L, Adams AB, Heiss E, Pearson TC, Larsen CP. NK cells mediate costimulation blockade-resistant rejection of allogeneic stem cells during nonmyeloablative transplantation. American Journal of Transplantation : Official Journal of the American Society of Transplantation and the American Society of Transplant Surgeons. 6: 292-304. PMID 16426313 DOI: 10.1111/J.1600-6143.2005.01172.X |
0.83 |
|
2006 |
Kemball CC, Lee ED, Szomolanyi-Tsuda E, Pearson TC, Larsen CP, Lukacher AE. Costimulation requirements for antiviral CD8+ T cells differ for acute and persistent phases of polyoma virus infection. Journal of Immunology (Baltimore, Md. : 1950). 176: 1814-24. PMID 16424212 DOI: 10.4049/Jimmunol.176.3.1814 |
0.482 |
|
2006 |
Newell KA, Larsen CP, Kirk AD. Transplant tolerance: converging on a moving target. Transplantation. 81: 1-6. PMID 16421467 DOI: 10.1097/01.Tp.0000179149.12979.13 |
0.372 |
|
2006 |
Li J, Gorechlad JW, Giver C, Larsen CP, Waller N. Apoptotic Cells Break Tolerance Induced by CD40-CD40L Blockade. Blood. 108: 3221-3221. DOI: 10.1182/Blood.V108.11.3221.3221 |
0.501 |
|
2006 |
Kean L, Adams A, Strobert E, Pearson T, Larsen C. Establishment of Chimerism in Rhesus Macaques through Nonmyeloablative Hematopoietic Stem Cell Transplant and Costimulation Blockade-Based Immunosuppression. Blood. 108: 3202-3202. DOI: 10.1182/Blood.V108.11.3202.3202 |
0.713 |
|
2006 |
Kean LS, Anderson AR, Oliva VL, Stempora L, Rigby MR, Pearson TC, Larsen CP. Immune monitoring in nonhuman primate transplantation. A review of "Non-human primate transplantation tolerance models: Immune Assays and Analysis Workshop" held in Atlanta, Ga, September 2005 Transplantation Reviews. 20: 139-145. DOI: 10.1016/J.Trre.2006.07.001 |
0.449 |
|
2006 |
Anderson A, Kean L, Gangappa S, Larsen C. F.144. Expansion and Suppressive Function of Rhesus Macaque Regulatory T-Cells Clinical Immunology. 119. DOI: 10.1016/J.Clim.2006.04.184 |
0.318 |
|
2006 |
Ford M, Koehn B, Wagener M, Borom K, Gangappa S, Pearson T, Larsen C. F.142. Inhibition of T-Cell Activation By CD28 and CD40L Blockade Is Influenced By T-Cell Precursor Frequency Clinical Immunology. 119: S100-S101. DOI: 10.1016/J.Clim.2006.04.182 |
0.76 |
|
2006 |
Koehn B, Borom K, Gangappa S, Pearson T, Larsen C. F.141. A Role for PD-1 in Maintaining Peripheral Tolerance to An Allogeneic Skin Graft Clinical Immunology. 119: S100. DOI: 10.1016/J.Clim.2006.04.181 |
0.71 |
|
2006 |
Li J, Giver C, Gorechlad J, Larsen C, Waller E. Apoptotic donor leukocytes inhibit tolerance and limit mixed chimerism induced by CD40-CD154 blockade in allogeneic bone marrow transplantation Biology of Blood and Marrow Transplantation. 12: 80. DOI: 10.1016/J.Bbmt.2005.11.250 |
0.528 |
|
2005 |
Vincenti F, Larsen C, Durrbach A, Wekerle T, Nashan B, Blancho G, Lang P, Grinyo J, Halloran PF, Solez K, Hagerty D, Levy E, Zhou W, Natarajan K, Charpentier B, et al. Costimulation blockade with belatacept in renal transplantation. The New England Journal of Medicine. 353: 770-81. PMID 16120857 DOI: 10.1056/Nejmoa050085 |
0.409 |
|
2005 |
Kemball CC, Lee ED, Vezys V, Pearson TC, Larsen CP, Lukacher AE. Late priming and variability of epitope-specific CD8+ T cell responses during a persistent virus infection. Journal of Immunology (Baltimore, Md. : 1950). 174: 7950-60. PMID 15944301 DOI: 10.4049/Jimmunol.174.12.7950 |
0.465 |
|
2005 |
Larsen CP, Pearson TC, Adams AB, Tso P, Shirasugi N, Strobert E, Anderson D, Cowan S, Price K, Naemura J, Emswiler J, Greene J, Turk LA, Bajorath J, Townsend R, et al. Rational development of LEA29Y (belatacept), a high-affinity variant of CTLA4-Ig with potent immunosuppressive properties. American Journal of Transplantation : Official Journal of the American Society of Transplantation and the American Society of Transplant Surgeons. 5: 443-53. PMID 15707398 DOI: 10.1111/J.1600-6143.2005.00749.X |
0.703 |
|
2005 |
Dai Z, Nasr IW, Reel M, Deng S, Diggs L, Larsen CP, Rothstein DM, Lakkis FG. Impaired recall of CD8 memory T cells in immunologically privileged tissue. Journal of Immunology (Baltimore, Md. : 1950). 174: 1165-70. PMID 15661869 DOI: 10.4049/Jimmunol.174.3.1165 |
0.47 |
|
2005 |
Adams AB, Shirasugi N, Jones TR, Durham MM, Strobert EA, Cowan S, Rees P, Hendrix R, Price K, Kenyon NS, Hagerty D, Townsend R, Hollenbaugh D, Pearson TC, Larsen CP. Development of a chimeric anti-CD40 monoclonal antibody that synergizes with LEA29Y to prolong islet allograft survival. Journal of Immunology (Baltimore, Md. : 1950). 174: 542-50. PMID 15611281 DOI: 10.4049/Jimmunol.174.1.542 |
0.675 |
|
2005 |
Emmanouilidis N, Larsen CP. Induction of chimerism and tolerance using freshly purified or cultured hematopoietic stem cells in nonmyeloablated mice. Methods in Molecular Medicine. 109: 459-68. PMID 15585938 DOI: 10.1385/1-59259-862-5:459 |
0.453 |
|
2005 |
Kean L, Hamby K, Pearson T, Larsen C. NK Cells Efficiently Prevent Engraftment of Donor Stem Cells after Tolerigenic Bone Marrow Transplantation. Blood. 106: 3025-3025. DOI: 10.1182/Blood.V106.11.3025.3025 |
0.479 |
|
2005 |
Kean L, Hamby K, Perry J, Larsen C, Archerq D. Berkeley Sickle Mice Demonstrate CD8- and NK1.1-Dependent Increased Rejection of Allogeneic Hematopoietic Stem Cell Transplants. Blood. 106: 2332-2332. DOI: 10.1182/Blood.V106.11.2332.2332 |
0.576 |
|
2005 |
Kokko KE, Newell KA, Pearson TC, Larsen CP. Enhanced immunosuppression induced by targeted mutation of cytotoxic T lymphocyte antigen 4-immunoglobulin Current Opinion in Organ Transplantation. 10: 265-269. DOI: 10.1097/01.Mot.0000186082.47623.76 |
0.548 |
|
2005 |
Nolen JDL, Bray RA, Pearson T, Larsen C, Newell K, Kokko K, Guasch A, Tso P, Gebel HM. A 5 year single center review of graft survival in sensitized renal transplant recipients Human Immunology. 66: 56. DOI: 10.1016/J.Humimm.2005.08.107 |
0.443 |
|
2005 |
Kean L, Hamby K, Coley S, Lee E, Adams A, Pearson T, Larsen C. NK cell alloreactivity is an important mediator of costimulation-blockade-resistant rejection during allogeneic transplantation Biology of Blood and Marrow Transplantation. 11: 36-37. DOI: 10.1016/J.Bbmt.2004.12.106 |
0.794 |
|
2004 |
Shirasugi N, Emmanouilidis N, Pearson TC, Larsen CP. Ability of donor splenocytes with costimulation blockade to induce mixed hematopoietic chimerism and transplantation tolerance Transplantation Proceedings. 36: 2423-2424. PMID 15561267 DOI: 10.1016/j.transproceed.2004.07.063 |
0.41 |
|
2004 |
Garber DA, Silvestri G, Barry AP, Fedanov A, Kozyr N, McClure H, Montefiori DC, Larsen CP, Altman JD, Staprans SI, Feinberg MB. Blockade of T cell costimulation reveals interrelated actions of CD4+ and CD8+ T cells in control of SIV replication. The Journal of Clinical Investigation. 113: 836-45. PMID 15067316 DOI: 10.1172/Jci19442 |
0.498 |
|
2004 |
Nanji SA, Hancock WW, Anderson CC, Adams AB, Luo B, Schur CD, Pawlick RL, Wang L, Coyle AJ, Larsen CP, Shapiro AM. Multiple combination therapies involving blockade of ICOS/B7RP-1 costimulation facilitate long-term islet allograft survival. American Journal of Transplantation : Official Journal of the American Society of Transplantation and the American Society of Transplant Surgeons. 4: 526-36. PMID 15023144 DOI: 10.1111/J.1600-6143.2004.00384.X |
0.696 |
|
2004 |
Larsen C, Durrbach A, Nashan B, Wekerle T, Blancho G, Lang P, Grinyo J, Halloran PF, Solez K, Hagerty D, Zhou W, Vincenti F. CO-STIMULATION BLOCKADE WITH LEA29Y IN A CALCINEURIN INHIBITOR FREE MAINTENANCE REGIMEN IN RENAL TRANSPLANT: 6-MONTH EFFICACY AND SAFETY Transplantation. 78: 264-265. DOI: 10.1097/00007890-200407271-00700 |
0.375 |
|
2004 |
Adams AB, Jones TR, Heiss EA, Shirasugi N, Rees PA, Yagita H, Pearson TC, Larsen CP. THE CD134/CD134L PATHWAY IS CRITICAL IN CD8-MEDIATED COSTIMULATION BLOCKADE RESISTANT REJECTION. Transplantation. 78: 181. DOI: 10.1097/00007890-200407271-00473 |
0.641 |
|
2004 |
Adams AB, Shirasugi N, Jones TR, Strobert EA, Durham MM, Hollenbaugh D, Hagerty D, Townsend R, Pearson TC, Larsen CP. BLOCKADE OF THE CD40-CD154 PATHWAY USING A CHIMERIC ANTI-HUMAN CD40 MONOCLONAL ANTIBODY SYNERGIZES WITH CD28 BLOCKADE TO PROLONG ISLET ALLOGRAFT SURVIVAL Transplantation. 78: 179-180. DOI: 10.1097/00007890-200407271-00470 |
0.641 |
|
2004 |
Milas Z, Adams A, Gourley T, Jones T, Durham M, Ahmed R, Pearson T, Larsen C. ANTI-CD40 LIGAND ANTIBODY AND ANTI-CD40 ISOTYPE IGG2B ANTIBODY INDUCE EQUIVALENT MURINE CHIMERISM AND SKIN GRAFT TOLERANCE UNLIKE ANTI-CD40 ISOTYPE IGG1 ANTIBODY. Transplantation. 78: 42. DOI: 10.1097/00007890-200407271-00122 |
0.609 |
|
2003 |
Jones TR, Shirasugi N, Adams AB, Pearson TC, Larsen CP. Intravital microscopy identifies selectins that regulate T cell traffic into allografts. The Journal of Clinical Investigation. 112: 1714-23. PMID 14660747 DOI: 10.1172/Jci19391 |
0.629 |
|
2003 |
Jones TR, Adams AB, Shirasugi NJ, Bingaman AW, Durham MM, Pearson TC, Larsen CP. Allogeneic parenchymal and hematopoietic tissues differ in their ability to induce deletion of donor-reactive T cells. American Journal of Transplantation : Official Journal of the American Society of Transplantation and the American Society of Transplant Surgeons. 3: 1520-30. PMID 14629282 DOI: 10.1046/J.1600-6135.2003.00262.X |
0.703 |
|
2003 |
Adams AB, Pearson TC, Larsen CP. Heterologous immunity: an overlooked barrier to tolerance. Immunological Reviews. 196: 147-60. PMID 14617203 DOI: 10.1046/J.1600-065X.2003.00082.X |
0.649 |
|
2003 |
Tso PL, Cash MP, Pearson TC, Larsen CP, Newell KA. Simultaneous pancreas-kidney transplantation utilizing a common arterial conduit: early experience and potential applications. American Journal of Transplantation : Official Journal of the American Society of Transplantation and the American Society of Transplant Surgeons. 3: 1440-3. PMID 14525607 DOI: 10.1046/J.1600-6135.2003.00236.X |
0.367 |
|
2003 |
Kean LS, Manci EA, Perry J, Balkan C, Coley S, Holtzclaw D, Adams AB, Larsen CP, Hsu LL, Archer DR. Chimerism and cure: hematologic and pathologic correction of murine sickle cell disease. Blood. 102: 4582-93. PMID 12933586 DOI: 10.1182/Blood-2003-03-0712 |
0.792 |
|
2003 |
Guo Z, Wang J, Dong Y, Adams AB, Shirasugi N, Kim O, Hart J, Newton-West M, Pearson TC, Larsen CP, Newell KA. Long-term survival of intestinal allografts induced by costimulation blockade, busulfan and donor bone marrow infusion. American Journal of Transplantation : Official Journal of the American Society of Transplantation and the American Society of Transplant Surgeons. 3: 1091-8. PMID 12919088 DOI: 10.1034/J.1600-6143.2003.00127.X |
0.662 |
|
2003 |
Adams AB, Shirasugi N, Jones TR, Williams MA, Durham MM, Ha J, Dong Y, Guo Z, Newell KA, Pearson TC, Larsen CP. Conventional immunosuppression is compatible with costimulation blockade-based, mixed chimerism tolerance induction. American Journal of Transplantation : Official Journal of the American Society of Transplantation and the American Society of Transplant Surgeons. 3: 895-901. PMID 12814483 DOI: 10.1034/J.1600-6143.2003.00155.X |
0.646 |
|
2003 |
Adams AB, Williams MA, Jones TR, Shirasugi N, Durham MM, Kaech SM, Wherry EJ, Onami T, Lanier JG, Kokko KE, Pearson TC, Ahmed R, Larsen CP. Heterologous immunity provides a potent barrier to transplantation tolerance. The Journal of Clinical Investigation. 111: 1887-95. PMID 12813024 DOI: 10.1172/Jci17477 |
0.639 |
|
2003 |
Larsson LC, Corbascio M, Pearson TC, Larsen CP, Ekberg H, Widner H. Induction of operational tolerance to discordant dopaminergic porcine xenografts. Transplantation. 75: 1448-54. PMID 12792495 DOI: 10.1097/01.Tp.0000058807.45320.A2 |
0.509 |
|
2003 |
Wang J, Guo Z, Dong Y, Kim O, Hart J, Adams A, Larsen CP, Mittler RS, Newell KA. Role of 4-1BB in allograft rejection mediated by CD8+ T cells. American Journal of Transplantation : Official Journal of the American Society of Transplantation and the American Society of Transplant Surgeons. 3: 543-51. PMID 12752310 DOI: 10.1034/J.1600-6143.2003.00088.X |
0.699 |
|
2003 |
Lögdberg L, Sgan SL, Larsen CP, Hillyer CD. Islet transplantation, stem cells, and transfusion medicine. Transfusion Medicine Reviews. 17: 95-109. PMID 12733103 DOI: 10.1053/Tmrv.2003.50006 |
0.462 |
|
2003 |
Williams MA, Adams AB, Walsh MB, Shirasugi N, Onami TM, Pearson TC, Ahmed R, Larsen CP. Primary and secondary immunocompetence in mixed allogeneic chimeras. Journal of Immunology (Baltimore, Md. : 1950). 170: 2382-9. PMID 12594261 DOI: 10.4049/Jimmunol.170.5.2382 |
0.672 |
|
2003 |
Nanji SA, Hancock WW, Anderson CC, Adams AB, Luo B, Wong L, Coyle AJ, Larsen CP, Shapiro AMJ. Targeting the ICOS-B7h Costimulatory Pathway Synergizes with Rapamycin to Regulate Alloresponses in Islet Transplantation Transplantation. 76: S51. DOI: 10.1097/00007890-200308271-00100 |
0.62 |
|
2003 |
Adams AB, Shirasugi N, Strobert EA, Cowan SR, Rees PA, Hendrix R, Kenyon NS, Pearson TC, Larsen CP. COMBINED CD40/CD28 BLOCKADE SYNERGIZES TO PROMOTE ISLET ALLOGRAFT SURVIVAL IN A NONHUMAN PRIMATE MODEL Transplantation. 76: S31. DOI: 10.1097/00007890-200308271-00039 |
0.65 |
|
2002 |
Arbiser JL, Bingaman A, Durham M, Cowan S, Cohen C, Zarnegar E, Varma V, Larsen CP. SVR angiosarcomas can be rejected by CD4 costimulation dependent and CD8 costimulation independent pathways. Molecular Medicine (Cambridge, Mass.). 8: 551-8. PMID 12456994 DOI: 10.1007/Bf03402165 |
0.455 |
|
2002 |
Williams MA, Onami TM, Adams AB, Durham MM, Pearson TC, Ahmed R, Larsen CP. Cutting edge: persistent viral infection prevents tolerance induction and escapes immune control following CD28/CD40 blockade-based regimen. Journal of Immunology (Baltimore, Md. : 1950). 169: 5387-91. PMID 12421910 DOI: 10.4049/Jimmunol.169.10.5387 |
0.642 |
|
2002 |
Pearson TC, Trambley J, Odom K, Anderson DC, Cowan S, Bray R, Lin A, Hollenbaugh D, Aruffo A, Siadak AW, Strobert E, Hennigar R, Larsen CP. Anti-CD40 therapy extends renal allograft survival in rhesus macaques. Transplantation. 74: 933-40. PMID 12394833 DOI: 10.1097/00007890-200210150-00006 |
0.84 |
|
2002 |
Shirasugi N, Adams AB, Durham MM, Lukacher AE, Xu H, Rees P, Cowan SR, Williams MA, Pearson TC, Larsen CP. Prevention of chronic rejection in murine cardiac allografts: a comparison of chimerism- and nonchimerism-inducing costimulation blockade-based tolerance induction regimens. Journal of Immunology (Baltimore, Md. : 1950). 169: 2677-84. PMID 12193741 DOI: 10.4049/Jimmunol.169.5.2677 |
0.688 |
|
2002 |
Corbascio M, Ekstrand H, Osterholm C, Qi Z, Simanaitis M, Larsen CP, Pearson TC, Riesbeck K, Ekberg H. CTLA4Ig combined with anti-LFA-1 prolongs cardiac allograft survival indefinitely. Transplant Immunology. 10: 55-61. PMID 12182466 DOI: 10.1016/S0966-3274(02)00014-X |
0.486 |
|
2002 |
Corbascio M, Mahanty H, Osterholm C, Qi Z, Pearson TC, Larsen CP, Freise CE, Ekberg H. Anti-lymphocyte function-associated antigen-1 monoclonal antibody inhibits CD40 ligand-independent immune responses and prevents chronic vasculopathy in CD40 ligand-deficient mice. Transplantation. 74: 35-41. PMID 12134096 DOI: 10.1097/00007890-200207150-00007 |
0.465 |
|
2002 |
Adams AB, Larsen CP, Pearson TC, Newell KA. The role of TNF receptor and TNF superfamily molecules in organ transplantation. American Journal of Transplantation : Official Journal of the American Society of Transplantation and the American Society of Transplant Surgeons. 2: 12-8. PMID 12095050 DOI: 10.1034/J.1600-6143.2002.020104.X |
0.631 |
|
2002 |
Onami TM, Harrington LE, Williams MA, Galvan M, Larsen CP, Pearson TC, Manjunath N, Baum LG, Pearce BD, Ahmed R. Dynamic regulation of T cell immunity by CD43. Journal of Immunology (Baltimore, Md. : 1950). 168: 6022-31. PMID 12055210 DOI: 10.4049/Jimmunol.168.12.6022 |
0.492 |
|
2002 |
Larsson LC, Corbascio M, Widner H, Pearson TC, Larsen CP, Ekberg H. Simultaneous inhibition of B7 and LFA-1 signaling prevents rejection of discordant neural xenografts in mice lacking CD40L. Xenotransplantation. 9: 68-76. PMID 12005106 DOI: 10.1034/J.1399-3089.2002.1O010.X |
0.389 |
|
2002 |
Kean LS, Durham MM, Adams AB, Hsu LL, Perry JR, Dillehay D, Pearson TC, Waller EK, Larsen CP, Archer DR. A cure for murine sickle cell disease through stable mixed chimerism and tolerance induction after nonmyeloablative conditioning and major histocompatibility complex-mismatched bone marrow transplantation. Blood. 99: 1840-9. PMID 11861303 DOI: 10.1182/Blood.V99.5.1840 |
0.663 |
|
2002 |
Malm H, Corbascio M, Osterholm C, Cowan S, Larsen CP, Pearson TC, Ekberg H. CTLA4ig induces long-term graft survival of allogeneic skin grafts and totally inhibits T-cell proliferation in LFA-1-deficient mice. Transplantation. 73: 293-7. PMID 11821746 DOI: 10.1097/00007890-200201270-00024 |
0.564 |
|
2002 |
Adams AB, Shirasugi N, Durham MM, Strobert E, Anderson D, Rees P, Cowan S, Xu H, Blinder Y, Cheung M, Hollenbaugh D, Kenyon NS, Pearson TC, Larsen CP. Calcineurin inhibitor-free CD28 blockade-based protocol protects allogeneic islets in nonhuman primates. Diabetes. 51: 265-70. PMID 11812731 DOI: 10.2337/Diabetes.51.2.265 |
0.679 |
|
2002 |
Jones TR, Ha J, Williams MA, Adams AB, Durham MM, Rees PA, Cowan SR, Pearson TC, Larsen CP. The role of the IL-2 pathway in costimulation blockade-resistant rejection of allografts. Journal of Immunology (Baltimore, Md. : 1950). 168: 1123-30. PMID 11801646 DOI: 10.4049/Jimmunol.168.3.1123 |
0.674 |
|
2002 |
Adams AB, Larsen CP, Pearson TC. Costimulation blockade and tolerance Current Opinion in Organ Transplantation. 7: 7-12. DOI: 10.1097/00075200-200203000-00003 |
0.648 |
|
2002 |
Larsen CP. Strategies for the induction of immune tolerance Third Smith and Nephew International Symposium - Translating Tissue Engineering Into Products. 37. |
0.372 |
|
2001 |
Suresh M, Whitmire JK, Harrington LE, Larsen CP, Pearson TC, Altman JD, Ahmed R. Role of CD28-B7 interactions in generation and maintenance of CD8 T cell memory. Journal of Immunology (Baltimore, Md. : 1950). 167: 5565-73. PMID 11698427 DOI: 10.4049/Jimmunol.167.10.5565 |
0.485 |
|
2001 |
Ha J, Bingaman AW, Durham MM, Pearson TC, Larsen CP. Aggressive skin allograft rejection in CD28-/- mice independent of the CD40/CD40L costimulatory pathway Transplant Immunology. 9: 13-17. PMID 11680567 DOI: 10.1016/S0966-3274(01)00043-0 |
0.497 |
|
2001 |
Williams MA, Tan JT, Adams AB, Durham MM, Shirasugi N, Whitmire JK, Harrington LE, Ahmed R, Pearson TC, Larsen CP. Characterization of virus-mediated inhibition of mixed chimerism and allospecific tolerance. Journal of Immunology (Baltimore, Md. : 1950). 167: 4987-95. PMID 11673506 DOI: 10.4049/Jimmunol.167.9.4987 |
0.692 |
|
2001 |
Bingaman AW, Ha J, Durham MM, Waitze SY, Tucker-Burden C, Cowan SR, Pearson TC, Larsen CP. Analysis of the CD40 and CD28 pathways on alloimmune responses by CD4+ T cells in vivo. Transplantation. 72: 1286-92. PMID 11602857 DOI: 10.1097/00007890-200110150-00018 |
0.479 |
|
2001 |
Akalin E, Hendrix RC, Polavarapu RG, Pearson TC, Neylan JF, Larsen CP, Lakkis FG. Gene expression analysis in human renal allograft biopsy samples using high-density oligoarray technology. Transplantation. 72: 948-953. PMID 11571464 DOI: 10.1097/00007890-200109150-00034 |
0.347 |
|
2001 |
Adams AB, Durham MM, Kean L, Shirasugi N, Ha J, Williams MA, Rees PA, Cheung MC, Mittelstaedt S, Bingaman AW, Archer DR, Pearson TC, Waller EK, Larsen CP. Costimulation blockade, busulfan, and bone marrow promote titratable macrochimerism, induce transplantation tolerance, and correct genetic hemoglobinopathies with minimal myelosuppression. Journal of Immunology (Baltimore, Md. : 1950). 167: 1103-11. PMID 11441122 DOI: 10.4049/Jimmunol.167.2.1103 |
0.667 |
|
2001 |
Guo Z, Meng L, Kim O, Wang J, Hart J, He G, Alegre ML, Thistlethwaite JR, Pearson TC, Larsen CP, Newell KA. CD8 T cell-mediated rejection of intestinal allografts is resistant to inhibition of the CD40/CD154 costimulatory pathway. Transplantation. 71: 1351-4. PMID 11403253 DOI: 10.1097/00007890-200105150-00033 |
0.502 |
|
2001 |
Adams AB, Pearson TC, Larsen CP. Conventional immunosuppression and co-stimulation blockade. Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences. 356: 703-5. PMID 11375073 DOI: 10.1098/Rstb.2001.0854 |
0.622 |
|
2001 |
Baldwin WM, Larsen CP, Fairchild RL. Innate immune responses to transplants: A significant variable with cadaver donors Immunity. 14: 369-376. PMID 11336682 DOI: 10.1016/S1074-7613(01)00117-0 |
0.488 |
|
2001 |
Meng L, Guo Z, Kim O, He G, Hart J, Szot GL, Wang J, Pearson TC, Larsen CP, Newell KA. Blockade of the CD40 pathway fails to prevent CD8 T cell-mediated intestinal allograft rejection. Transplantation Proceedings. 33: 418-20. PMID 11266891 DOI: 10.1016/S0041-1345(00)02075-3 |
0.522 |
|
2001 |
Trambley J, Lin A, Elwood E, Bingaman AW, Lakkis F, Corbascio M, Pearson TC, Larsen CP. FasL is important in costimulation blockade-resistant skin graft rejection. Transplantation. 71: 537-43. PMID 11258433 DOI: 10.1097/00007890-200102270-00009 |
0.847 |
|
2000 |
Bingaman AW, Pearson TC, Larsen CP. The role of CD40L in T cell-dependent nitric oxide production by murine macrophages Transplant Immunology. 8: 195-202. PMID 11147700 DOI: 10.1016/S0966-3274(00)00026-5 |
0.422 |
|
2000 |
Williams MA, Trambley J, Ha J, Adams AB, Durham MM, Rees P, Cowan SR, Pearson TC, Larsen CP. Genetic characterization of strain differences in the ability to mediate CD40/CD28-independent rejection of skin allografts. Journal of Immunology (Baltimore, Md. : 1950). 165: 6849-57. PMID 11120808 DOI: 10.4049/Jimmunol.165.12.6849 |
0.82 |
|
2000 |
Triemer HL, Pearson TC, Odom KL, Larsen CP. Analysis of a single-center experience with mycophenolate mofetil based immunosuppression in renal transplantation. Clinical Transplantation. 14: 413-20. PMID 10946781 DOI: 10.1034/J.1399-0012.2000.14041002.X |
0.433 |
|
2000 |
Bingaman AW, Waitze SY, Alexander DZ, Cho HR, Lin A, Tucker-Burden C, Cowan SR, Pearson TC, Larsen CP. Transplantation of the bone marrow microenvironment leads to hematopoietic chimerism without cytoreductive conditioning. Transplantation. 69: 2491-6. PMID 10910268 DOI: 10.1097/00007890-200006270-00006 |
0.447 |
|
2000 |
Durham MM, Bingaman AW, Adams AB, Ha J, Waitze SY, Pearson TC, Larsen CP. Cutting edge: administration of anti-CD40 ligand and donor bone marrow leads to hemopoietic chimerism and donor-specific tolerance without cytoreductive conditioning. Journal of Immunology (Baltimore, Md. : 1950). 165: 1-4. PMID 10861026 DOI: 10.4049/Jimmunol.165.1.1 |
0.699 |
|
2000 |
Bingaman AW, Ha J, Waitze SY, Durham MM, Cho HR, Tucker-Burden C, Hendrix R, Cowan SR, Pearson TC, Larsen CP. Vigorous allograft rejection in the absence of danger. Journal of Immunology (Baltimore, Md. : 1950). 164: 3065-71. PMID 10706695 DOI: 10.4049/Jimmunol.164.6.3065 |
0.475 |
|
2000 |
Tan JT, Whitmire JK, Murali-Krishna K, Ahmed R, Altman JD, Mittler RS, Sette A, Pearson TC, Larsen CP. 4-1BB costimulation is required for protective anti-viral immunity after peptide vaccination. Journal of Immunology (Baltimore, Md. : 1950). 164: 2320-5. PMID 10679066 DOI: 10.4049/Jimmunol.164.5.2320 |
0.385 |
|
2000 |
Trambley J, Pearson TC, Larsen CP. Interpreting murine tolerance experiments Current Opinion in Organ Transplantation. 5: 103-107. DOI: 10.1097/00075200-200006000-00011 |
0.753 |
|
2000 |
Meng L, Guo Z, Kim O, He G, Hart J, Szot GL, Wang J, Larsen CP, Newell KA. BLOCKADE OF THE CD40 COSTIMULATORY PATHWAY FAILS TO PREVENT CD8 T CELL- MEDIATED REJECTION OF INTESTINAL ALLOGRAFTS.: Abstract# 1163 Transplantation. 69. DOI: 10.1097/00007890-200004271-01163 |
0.522 |
|
2000 |
Trambley JF, Lin A, Elwood ET, Lakkis FG, Pearson TC, Larsen CP. FAS LIGAND PLAYS A CRUCIAL ROLE IN COSTIMULATION BLOCKADE RESISTANT REJECTION.: Abstract# 1097 Transplantation. 69. DOI: 10.1097/00007890-200004271-01097 |
0.762 |
|
2000 |
Bingaman AW, Durham MM, Adams AB, Ha J, Pearson TC, Larsen CP. HEMATOPOIETIC CHIMERISM IN THE PRESENCE OF CD40 AND CD28 BLOCKADE LEADS TO PERIPHERAL DELETION OF DONOR REACTIVE T CELLS AND DEVELOPMENT OF DONOR SPECIFIC TRANSPLANTATION TOLERANCE. Transplantation. 69: S240. DOI: 10.1097/00007890-200004271-00495 |
0.731 |
|
2000 |
Durham MM, Bingaman AW, Adams AB, Ha J, Waitze S, Pearson TC, Larsen CP. ADMINISTRATION OF REPEATED DOSES OF ANTI-CD40L AND DONOR BONE MARROW LEADS TO HEMATOPOIETIC CHIMERISM AND DONOR SPECIFIC TOLERANCE WITHOUT CYTOREDUCTIVE CONDITIONING. Transplantation. 69: S240. DOI: 10.1097/00007890-200004271-00494 |
0.578 |
|
2000 |
Ha J, Bingaman AW, Durham MM, Adams AB, Pearson TC, Larsen CP. ROLE OF CD40L IN THE INITIATION, AMPLIFICATION, AND EFFECTOR PHASE OF ALLOIMMUNE RESPONSES. Transplantation. 69: S131. DOI: 10.1097/00007890-200004271-00076 |
0.5 |
|
2000 |
Larsen CP, Odom K, Hollenbaugh D, Bray R, Hennigar R, Pearson TC. PROLONGATION OF RENAL ALLOGRAFT SURVIVAL BY A CHIMERIC ANTI-HUMAN CD40 MONOCLONAL ANTIBODY IN NONHUMAN PRIMATES.: Abstract# 45 Transplantation. 69. DOI: 10.1097/00007890-200004271-00045 |
0.416 |
|
2000 |
Pearson TC, Lin A, Odom K, Cowan S, Peach R, Haggerty D, Larsen CP. PROLONGATION OF RENAL ALLOGRAFT SURVIVAL WITH BLOCKADE OF THE CD28 PATHWAY USING A NOVEL MUTANT CTLA4-IG FUSION PROTEIN IN NON-HUMAN PRIMATES.: Abstract# 44 Transplantation. 69. DOI: 10.1097/00007890-200004271-00044 |
0.427 |
|
1999 |
Trambley J, Bingaman AW, Lin A, Elwood ET, Waitze SY, Ha J, Durham MM, Corbascio M, Cowan SR, Pearson TC, Larsen CP. Asialo GM1(+) CD8(+) T cells play a critical role in costimulation blockade-resistant allograft rejection. The Journal of Clinical Investigation. 104: 1715-22. PMID 10606625 DOI: 10.1172/Jci8082 |
0.837 |
|
1999 |
Tan JT, Whitmire JK, Ahmed R, Pearson TC, Larsen CP. 4-1BB ligand, a member of the TNF family, is important for the generation of antiviral CD8 T cell responses Journal of Immunology. 163: 4859-4868. PMID 10528187 |
0.389 |
|
1999 |
Whitmire JK, Flavell RA, Grewal IS, Larsen CP, Pearson TC, Ahmed R. CD40-CD40 ligand costimulation is required for generating antiviral CD4 T cell responses but is dispensable for CD8 T cell responses Journal of Immunology. 163: 3194-3201. PMID 10477587 |
0.377 |
|
1999 |
Bingaman AW, Ha J, Waitze SR, Tucker-Burden C, Pearson TC, Larsen CP. Analysis of the CD40 and CD28 T cell Costimulatory Pathways in Allograft Rejection Mediated by CD4 and CD8 T cell Subsets Transplantation. 67: S262. DOI: 10.1097/00007890-199904150-01046 |
0.502 |
|
1999 |
Trambley J, Bingaman A, Lin A, Larsen C, Pearson T. Asialo Gm1+ Cd8+ Cells Play An Important Role In Costimulatory Blockade Resistant Rejection Transplantation. 67. DOI: 10.1097/00007890-199904150-00453 |
0.814 |
|
1999 |
Bingaman AW, Waitze SR, Alexander DZ, Cho HR, Tucker-Burden C, Cowan SR, Pearson TC, Larsen CP. Transplantation of the Bone Marrow Microenvironment Leads to Hematopoietic Chimerism and Shapes the T cell Repertoire without Cytoreductive Conditioning Transplantation. 67: S34. DOI: 10.1097/00007890-199904150-00139 |
0.44 |
|
1998 |
Elwood ET, Larsen CP, Cho HR, Corbascio M, Ritchie SC, Alexander DZ, Tucker-Burden C, Linsley PS, Aruffo A, Hollenbaugh D, Winn KJ, Pearson TC. Prolonged acceptance of concordant and discordant xenografts with combined CD40 and CD28 pathway blockade. Transplantation. 65: 1422-8. PMID 9645796 DOI: 10.1097/00007890-199806150-00002 |
0.447 |
|
1998 |
Waitze SR, Pearson TC, Cho HR, Tucker-Burden C, Elwood ET, Linsley PS, Hollenbaugh D, Aruffo A, Larsen CP. Prolongation Of Murine Cardiac And Skin Allograft Survival By Anti-Cd40 Monoclonal Antibody Transplantation. 65: 206. DOI: 10.1097/00007890-199805131-00510 |
0.401 |
|
1998 |
Pelletier RP, Bergese SD, Klenotic SM, Alexander DZ, Larsen CP, Pearson TC, VanBuskirk AM, Ferguson RM, Orosz CG. Alloantibodies Are Not Required For Development Of Transplant Vascular Sclerosis Transplantation. 65: 174. DOI: 10.1097/00007890-199805131-00381 |
0.41 |
|
1998 |
Lin A, Elwood ET, Corbascio M, Tucker-Burden C, Lakkis F, Linsley PS, Hollenbaugh D, Aruffo A, Pearson TC, Larsen CP. Fas Ligand And Nk Cells Are Important Mediators Of Late Skin Graft Rejection Transplantation. 65: 80. DOI: 10.1097/00007890-199805131-00006 |
0.375 |
|
1997 |
Larsen CP, Pearson TC. The CD40 pathway in allograft rejection, acceptance, and tolerance Current Opinion in Immunology. 9: 641-647. PMID 9368772 DOI: 10.1016/S0952-7915(97)80043-X |
0.502 |
|
1997 |
Shuford WW, Klussman K, Tritchler DD, Loo DT, Chalupny J, Siadak AW, Brown TJ, Emswiler J, Raecho H, Larsen CP, Pearson TC, Ledbetter JA, Aruffo A, Mittler RS. 4-1BB costimulatory signals preferentially induce CD8+ T cell proliferation and lead to the amplification in vivo of cytotoxic T cell responses. The Journal of Experimental Medicine. 186: 47-55. PMID 9206996 DOI: 10.1084/Jem.186.1.47 |
0.525 |
|
1997 |
Pearson TC, Alexander DZ, Corbascio M, Hendrix R, Ritchie SC, Linsley PS, Faherty D, Larsen CP. Analysis of the B7 costimulatory pathway in allograft rejection Transplantation. 63: 1463-1469. PMID 9175811 DOI: 10.1097/00007890-199705270-00016 |
0.442 |
|
1997 |
Elwood ET, Larsen CP, Maurer DH, Routenberg KL, Neylan JF, Whelchel JD, O'Brien DP, Pearson TC. Microchimerism and rejection in clinical transplantation. Lancet. 349: 1358-60. PMID 9149698 DOI: 10.1016/S0140-6736(96)09105-2 |
0.453 |
|
1996 |
Alexander DZ, Pearson TC, Hendrix R, Ritchie SC, Larsen CP. Analysis of effector mechanisms in murine cardiac allograft rejection Transplant Immunology. 4: 46-48. PMID 8762009 DOI: 10.1016/S0966-3274(96)80033-5 |
0.502 |
|
1996 |
Larsen CP, Elwood ET, Alexander DZ, Ritchie SC, Hendrix R, Tucker-Burden C, Cho HR, Aruffo A, Hollenbaugh D, Linsley PS, Winn KJ, Pearson TC. Long-term acceptance of skin and cardiac allografts after blocking CD40 and CD28 pathways. Nature. 381: 434-8. PMID 8632801 DOI: 10.1038/381434A0 |
0.527 |
|
1996 |
Pearson TC, Alexander DZ, Hendrix R, Elwood ET, Linsley PS, Winn KJ, Larsen CP. CTLA4-Ig plus bone marrow induces long-term allograft survival and donor-specific unresponsiveness in the murine model: Evidence for Hematopoietic Chimerism Transplantation. 61: 997-1004. PMID 8623206 DOI: 10.1097/00007890-199604150-00002 |
0.506 |
|
1996 |
Larsen CP, Alexander DZ, Hollenbaugh D, Elwood ET, Ritchie SC, Aruffo A, Hendrix R, Pearson TC. CD40-gp39 interactions play a critical role during allograft rejection. Suppression of allograft rejection by blockade of the CD40-gp39 pathway. Transplantation. 61: 4-9. PMID 8560571 DOI: 10.1097/00007890-199601150-00002 |
0.538 |
|
1995 |
Gerber DA, Oettinger CW, Phd MDs, Milton GV, Larsen CP, Pearson TC. Prolongation of murine cardiac allograft survival by microspheres containing TNFα and IL1-β neutralizing antibodies Journal of Drug Targeting. 3: 311-315. PMID 8821005 DOI: 10.3109/10611869509015960 |
0.33 |
|
1995 |
Thomson AW, Lu L, Wan Y, Qian S, Larsen CP, Starzl TE. Identification of donor-derived dendritic cell progenitors in bone marrow of spontaneously tolerant liver allograft recipients Transplantation. 60: 1555-1559. PMID 8545889 DOI: 10.1097/00007890-199560120-00030 |
0.453 |
|
1995 |
Roake JA, Rao AS, Morris PJ, Larsen CP, Hankins DF, Austyn JM. Systemic lipopolysaccharide recruits dendritic cell progenitors to nonlymphoid tissues Transplantation. 59: 1319-1324. PMID 7762069 DOI: 10.1097/00007890-199505000-00017 |
0.489 |
|
1995 |
Larsen CP, Alexander DZ, Hendrix R, Ritchie SC, Pearson TC. Fas-mediated cytotoxicity: An immunoeffector or immunoregulatory pathway inT cell-mediated immune responses? Transplantation. 60: 221-224. PMID 7544034 DOI: 10.1097/00007890-199508000-00002 |
0.469 |
|
1995 |
Pearson TC, Alexander DZ, Larsen CP. Role of graft in transplantation tolerance (answer) Transplantation. 59: 450. DOI: 10.1097/00007890-199502000-00031 |
0.465 |
|
1994 |
Pearson TC, Alexander DZ, Winn KJ, Linsley PS, Lowry RP, Larsen CP. Transplantation tolerance induced by CTLA4-Ig Transplantation. 57: 1701-1706. PMID 8016872 DOI: 10.1097/00007890-199406270-00002 |
0.579 |
|
1993 |
Rao AS, Roake JA, Larsen CP, Hankins DF, Morris PJ, Austyn JM. Isolation of dendritic leukocytes from non-lymphoid organs Advances in Experimental Medicine and Biology. 329: 507-512. PMID 8379418 DOI: 10.1007/978-1-4615-2930-9_85 |
0.319 |
|
1992 |
Pearson TC, Madsen JC, Larsen CP, Morris PJ, Wood KJ. Induction of transplantation tolerance in adults using donor antigen and anti-CD4 monoclonal antibody Transplantation. 54: 475-483. PMID 1384183 DOI: 10.1097/00007890-199209000-00018 |
0.551 |
|
1992 |
Larsen CP, Ritchie SC, Pearson TC, Linsley PS, Lowry RP. Functional expression of the costimulatory molecule, B7/BB1, on murine dendritic cell populations Journal of Experimental Medicine. 176: 1215-1220. PMID 1328465 DOI: 10.1084/Jem.176.4.1215 |
0.368 |
|
1990 |
Austyn JM, Larsen CP. Migration patterns of dendritic leukocytes: Implications for transplantation Transplantation. 49: 1-7. PMID 2405548 DOI: 10.1097/00007890-199001000-00001 |
0.403 |
|
1990 |
Larsen CP, Morris PJ, Austyn JM. Migration of dendritic leukocytes from cardiac allografts into host spleens: A novel pathway for initiation of rejection Journal of Experimental Medicine. 171: 307-314. PMID 2404081 DOI: 10.1084/Jem.171.1.307 |
0.482 |
|
1990 |
Larsen CP, Barker H, Morris PJ, Austyn JM. Failure of mature dendritic cells of the host to migrate from the blood into cardiac or skin allografts Transplantation. 50: 294-301. PMID 2382296 DOI: 10.1097/00007890-199008000-00025 |
0.475 |
|
1990 |
Larsen CP, Steinman RM, Witmer-Pack M, Hankins DF, Morris PJ, Austyn JM. Migration and maturation of Langerhans cells in skin transplants and explants Journal of Experimental Medicine. 172: 1483-1493. PMID 2230654 DOI: 10.1084/Jem.172.5.1483 |
0.443 |
|
1990 |
Larsen CP, Austyn JM, Morris PJ. The role of graft-derived dendritic leukocytes in the rejection of vascularized organ allografts: Recent findings on the migration and function of dendritic leukocytes after transplantation Annals of Surgery. 212: 308-315. PMID 2204317 DOI: 10.1097/00000658-199009000-00009 |
0.516 |
|
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