| Year |
Citation |
Score |
| 2024 |
Pérot JB, Niewiadomska-Cimicka A, Brouillet E, Trottier Y, Flament J. Longitudinal MRI and 1H-MRS study of SCA7 mouse forebrain reveals progressive multiregional atrophy and early brain metabolite changes indicating early neuronal and glial dysfunction. Plos One. 19: e0296790. PMID 38227598 DOI: 10.1371/journal.pone.0296790 |
0.315 |
|
| 2022 |
Abjean L, Ben Haim L, Riquelme-Perez M, Gipchtein P, Derbois C, Palomares MA, Petit F, Hérard AS, Gaillard MC, Guillermier M, Gaudin-Guérif M, Aurégan G, Sagar N, Héry C, Dufour N, ... ... Brouillet E, et al. Reactive astrocytes promote proteostasis in Huntington's disease through the JAK2-STAT3 pathway. Brain : a Journal of Neurology. PMID 35298632 DOI: 10.1093/brain/awac068 |
0.37 |
|
| 2021 |
Niewiadomska-Cimicka A, Doussau F, Perot JB, Roux MJ, Keime C, Hache A, Piguet F, Novati A, Weber C, Yalcin B, Meziane H, Champy MF, Grandgirard E, Karam A, Messaddeq N, ... ... Brouillet E, et al. SCA7 mouse cerebellar pathology reveals preferential downregulation of key Purkinje cell-identity genes and shared disease signature with SCA1 and SCA2. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. PMID 33888607 DOI: 10.1523/JNEUROSCI.1882-20.2021 |
0.302 |
|
| 2020 |
Pépin J, de Longprez L, Trovero F, Brouillet E, Valette J, Flament J. Complementarity of gluCEST and H-MRS for the study of mouse models of Huntington's disease. Nmr in Biomedicine. e4301. PMID 32198958 DOI: 10.1002/Nbm.4301 |
0.424 |
|
| 2020 |
Guillemaud O, Ceyzériat K, Saint-Georges T, Cambon K, Petit F, Ben Haim L, Carrillo-de Sauvage MA, Guillermier M, Bernier S, Hérard AS, Joséphine C, Bémelmans AP, Brouillet E, Hantraye P, Bonvento G, et al. Complex roles for reactive astrocytes in the triple transgenic mouse model of Alzheimer disease. Neurobiology of Aging. PMID 32171592 DOI: 10.1016/J.Neurobiolaging.2020.02.010 |
0.334 |
|
| 2020 |
Le Douce J, Maugard M, Veran J, Matos M, Jégo P, Vigneron PA, Faivre E, Toussay X, Vandenberghe M, Balbastre Y, Piquet J, Guiot E, Tran NT, Taverna M, Marinesco S, ... ... Brouillet E, et al. Impairment of Glycolysis-Derived l-Serine Production in Astrocytes Contributes to Cognitive Deficits in Alzheimer's Disease. Cell Metabolism. 31: 503-517.e8. PMID 32130882 DOI: 10.1016/J.Cmet.2020.02.004 |
0.304 |
|
| 2019 |
Cresto N, Gaillard MC, Gardier C, Gubinelli F, Diguet E, Bellet D, Legroux L, Mitja J, Auregan G, Guillermier M, Josephine C, Jan C, Dufour N, Joliot A, Hantraye P, ... ... Brouillet E, et al. The C-terminal domain of LRRK2 with the G2019S mutation is sufficient to produce neurodegeneration of dopaminergic neurons in vivo. Neurobiology of Disease. 104614. PMID 31605779 DOI: 10.1016/J.Nbd.2019.104614 |
0.415 |
|
| 2019 |
Brouillet E, Merienne K. What is gained or 'lost in translation' in Huntington's disease. Brain : a Journal of Neurology. 142: 2900-2902. PMID 31560061 DOI: 10.1093/Brain/Awz274 |
0.334 |
|
| 2019 |
Gary C, Lam S, Hérard AS, Koch JE, Petit F, Gipchtein P, Sawiak SJ, Caillierez R, Eddarkaoui S, Colin M, Aujard F, Deslys JP, Brouillet E, Buée L, et al. Encephalopathy induced by Alzheimer brain inoculation in a non-human primate. Acta Neuropathologica Communications. 7: 126. PMID 31481130 DOI: 10.1186/S40478-019-0771-X |
0.422 |
|
| 2019 |
Ligneul C, Palombo M, Hernández-Garzón E, Carrillo-de Sauvage MA, Flament J, Hantraye P, Brouillet E, Bonvento G, Escartin C, Valette J. Diffusion-weighted magnetic resonance spectroscopy enables cell-specific monitoring of astrocyte reactivity in vivo. Neuroimage. 191: 457-469. PMID 30818026 DOI: 10.1016/J.Neuroimage.2019.02.046 |
0.328 |
|
| 2018 |
Ceyzériat K, Ben Haim L, Denizot A, Pommier D, Matos M, Guillemaud O, Palomares MA, Abjean L, Petit F, Gipchtein P, Gaillard MC, Guillermier M, Bernier S, Gaudin M, Aurégan G, ... ... Brouillet E, et al. Modulation of astrocyte reactivity improves functional deficits in mouse models of Alzheimer's disease. Acta Neuropathologica Communications. 6: 104. PMID 30322407 DOI: 10.1186/S40478-018-0606-1 |
0.394 |
|
| 2018 |
Cresto N, Gardier C, Gubinelli F, Gaillard MC, Liot G, West AB, Brouillet E. The Unlikely Partnership Between LRRK2 and α-Synuclein in Parkinson's Disease. The European Journal of Neuroscience. PMID 30269383 DOI: 10.1111/Ejn.14182 |
0.359 |
|
| 2018 |
Galvan L, Francelle L, Gaillard MC, de Longprez L, Carrillo-de Sauvage MA, Liot G, Cambon K, Stimmer L, Luccantoni S, Flament J, Valette J, de Chaldée M, Auregan G, Guillermier M, Joséphine C, ... ... Brouillet E, et al. The striatal kinase DCLK3 produces neuroprotection against mutant huntingtin. Brain : a Journal of Neurology. PMID 29534157 DOI: 10.1093/Brain/Awy057 |
0.782 |
|
| 2018 |
Abjean L, Haim LB, Sauvage MAC, Hérard A, Derbois C, Petit F, Gipstein P, Guillermier M, Gaudin M, Bernier S, Dufour N, Bémelmans A, Deleuze J, Hantraye P, Bonvento G, ... ... Brouillet E, et al. A42 Reactive astrocytes promote proteostasis in huntington’s disease Journal of Neurology, Neurosurgery, and Psychiatry. 89. DOI: 10.1136/Jnnp-2018-Ehdn.40 |
0.432 |
|
| 2017 |
d'Orange M, Aurégan G, Cheramy D, Gaudin-Guérif M, Lieger S, Guillermier M, Stimmer L, Joséphine C, Hérard AS, Gaillard MC, Petit F, Kiessling MC, Schmitz C, Colin M, Buée L, ... ... Brouillet E, et al. Potentiating tangle formation reduces acute toxicity of soluble tau species in the rat. Brain : a Journal of Neurology. PMID 29253129 DOI: 10.1093/Brain/Awx342 |
0.394 |
|
| 2017 |
Merienne N, Vachey G, de Longprez L, Meunier C, Zimmer V, Perriard G, Canales M, Mathias A, Herrgott L, Beltraminelli T, Maulet A, Dequesne T, Pythoud C, Rey M, Pellerin L, ... Brouillet E, et al. The Self-Inactivating KamiCas9 System for the Editing of CNS Disease Genes. Cell Reports. 20: 2980-2991. PMID 28930690 DOI: 10.1016/J.Celrep.2017.08.075 |
0.388 |
|
| 2017 |
Bonvento G, Valette J, Flament J, Mochel F, Brouillet E. Imaging and spectroscopic approaches to probe brain energy metabolism dysregulation in neurodegenerative diseases. Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism. 271678X17697989. PMID 28276944 DOI: 10.1177/0271678X17697989 |
0.384 |
|
| 2017 |
Le Gras S, Keime C, Anthony A, Lotz C, De Longprez L, Brouillet E, Cassel JC, Boutillier AL, Merienne K. Altered enhancer transcription underlies Huntington's disease striatal transcriptional signature. Scientific Reports. 7: 42875. PMID 28225006 DOI: 10.1038/Srep42875 |
0.46 |
|
| 2017 |
Francelle L, Lotz C, Outeiro T, Brouillet E, Merienne K. Contribution of Neuroepigenetics to Huntington's Disease. Frontiers in Human Neuroscience. 11: 17. PMID 28194101 DOI: 10.3389/Fnhum.2017.00017 |
0.769 |
|
| 2016 |
Galan-Rodriguez B, Martin E, Brouillet E, Déglon N, Betuing S, Caboche J. Coupling of d2R short but not d2R Long receptor isoform to the Rho/Rock signaling pathway renders striatal neurons vulnerable to mutant huntingtin. The European Journal of Neuroscience. PMID 27717053 DOI: 10.1111/Ejn.13415 |
0.424 |
|
| 2016 |
Liot G, Valette J, Pépin J, Flament J, Brouillet E. Energy defects in Huntington's disease: Why "in vivo" evidence matters. Biochemical and Biophysical Research Communications. PMID 27639641 DOI: 10.1016/J.Bbrc.2016.09.065 |
0.451 |
|
| 2016 |
Pépin J, Francelle L, Carrillo-de Sauvage MA, de Longprez L, Gipchtein P, Cambon K, Valette J, Brouillet E, Flament J. In vivo imaging of brain glutamate defects in a knock-in mouse model of Huntington's disease. Neuroimage. 139: 53-64. PMID 27318215 DOI: 10.1016/J.Neuroimage.2016.06.023 |
0.775 |
|
| 2016 |
Flament J, Pépin J, Francelle L, Sauvage MC, Longprez Ld, Gipchtein P, Cambon K, Valette J, Brouillet E. B40 In vivo imaging of brain glutamate defects in a knock-in mouse model of huntington’s disease Journal of Neurology, Neurosurgery, and Psychiatry. 87. DOI: 10.1136/Jnnp-2016-314597.71 |
0.745 |
|
| 2016 |
Ceyzeriat K, Haim LB, Saint-Georges T, Petit F, Houitte D, Guillermier M, Berniard A, Mitja J, Josephine C, Hantraye P, Brouillet E, Cambon K, Dhenain M, Bonvento G, Escartin C. Specific Inhibition Of Astrocyte Reactivity Improves Some Disease Outcomes In Alzheimer'S Disease Mice Alzheimers & Dementia. 12: 242. DOI: 10.1016/J.Jalz.2016.06.433 |
0.352 |
|
| 2016 |
Douce JL, Veran J, Jego P, Faivre E, Herard A, Taverna M, Brouillet E, Toussay X, Cauli B, Oliet S, Panatier A, Bonvento G. Deficits Of Synaptic Plasticity In A Mouse Model Of Alzheimer'S Disease Are Linked To Astrocytic L-Serine Production Alzheimers & Dementia. 12: 1043. DOI: 10.1016/J.Jalz.2016.06.2167 |
0.32 |
|
| 2015 |
Rocher AB, Gubellini P, Merienne N, Boussicault L, Petit F, Gipchtein P, Jan C, Hantraye P, Brouillet E, Bonvento G. Synaptic scaling up in medium spiny neurons of aged BACHD mice: A slow-progression model of Huntington's disease. Neurobiology of Disease. PMID 26626081 DOI: 10.1016/J.Nbd.2015.10.016 |
0.425 |
|
| 2015 |
Carrillo-de Sauvage MA, Flament J, Bramoulle Y, Ben Haim L, Guillermier M, Berniard A, Aurégan G, Houitte D, Brouillet E, Bonvento G, Hantraye P, Valette J, Escartin C. The neuroprotective agent CNTF decreases neuronal metabolites in the rat striatum: an in vivo multimodal magnetic resonance imaging study. Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism. 35: 917-21. PMID 25833344 DOI: 10.1038/Jcbfm.2015.48 |
0.433 |
|
| 2015 |
Ben Haim L, Ceyzériat K, Carrillo-de Sauvage MA, Aubry F, Auregan G, Guillermier M, Ruiz M, Petit F, Houitte D, Faivre E, Vandesquille M, Aron-Badin R, Dhenain M, Déglon N, Hantraye P, ... Brouillet E, et al. The JAK/STAT3 pathway is a common inducer of astrocyte reactivity in Alzheimer's and Huntington's diseases. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 35: 2817-29. PMID 25673868 DOI: 10.1523/Jneurosci.3516-14.2015 |
0.407 |
|
| 2015 |
Francelle L, Galvan L, Gaillard MC, Petit F, Bernay B, Guillermier M, Bonvento G, Dufour N, Elalouf JM, Hantraye P, Déglon N, de Chaldée M, Brouillet E. The striatal long noncoding RNA Abhd11os is neuroprotective against an N-terminal fragment of mutant huntingtin in vivo. Neurobiology of Aging. 36: 1601.e7-16. PMID 25619660 DOI: 10.1016/J.Neurobiolaging.2014.11.014 |
0.749 |
|
| 2015 |
Francelle L, Galvan L, Gaillard MC, Guillermier M, Houitte D, Bonvento G, Petit F, Jan C, Dufour N, Hantraye P, Elalouf JM, De Chaldée M, Déglon N, Brouillet E. Loss of the thyroid hormone-binding protein Crym renders striatal neurons more vulnerable to mutant huntingtin in Huntington's disease. Human Molecular Genetics. 24: 1563-73. PMID 25398949 DOI: 10.1093/Hmg/Ddu571 |
0.783 |
|
| 2015 |
Blum D, Herrera F, Francelle L, Mendes T, Basquin M, Obriot H, Demeyer D, Sergeant N, Gerhardt E, Brouillet E, Buée L, Outeiro TF. Mutant huntingtin alters Tau phosphorylation and subcellular distribution. Human Molecular Genetics. 24: 76-85. PMID 25143394 DOI: 10.1093/Hmg/Ddu421 |
0.743 |
|
| 2014 |
Francelle L, Galvan L, Brouillet E. Possible involvement of self-defense mechanisms in the preferential vulnerability of the striatum in Huntington's disease. Frontiers in Cellular Neuroscience. 8: 295. PMID 25309327 DOI: 10.3389/Fncel.2014.00295 |
0.78 |
|
| 2014 |
Boussicault L, Hérard AS, Calingasan N, Petit F, Malgorn C, Merienne N, Jan C, Gaillard MC, Lerchundi R, Barros LF, Escartin C, Delzescaux T, Mariani J, Hantraye P, Beal MF, ... Brouillet E, et al. Impaired brain energy metabolism in the BACHD mouse model of Huntington's disease: critical role of astrocyte-neuron interactions. Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism. 34: 1500-10. PMID 24938402 DOI: 10.1038/Jcbfm.2014.110 |
0.579 |
|
| 2014 |
Brouillet E. The 3-NP Model of Striatal Neurodegeneration. Current Protocols in Neuroscience / Editorial Board, Jacqueline N. Crawley ... [Et Al.]. 67: 9.48.1-9.48.14. PMID 24723322 DOI: 10.1002/0471142301.Ns0948S67 |
0.384 |
|
| 2014 |
Facchinetti P, Dorard E, Contremoulins V, Gaillard MC, Déglon N, Sazdovitch V, Guihenneuc-Jouyaux C, Brouillet E, Duyckaerts C, Allinquant B. SET translocation is associated with increase in caspase cleaved amyloid precursor protein in CA1 of Alzheimer and Down syndrome patients. Neurobiology of Aging. 35: 958-68. PMID 24262202 DOI: 10.1016/J.Neurobiolaging.2013.08.039 |
0.312 |
|
| 2013 |
Damiano M, Diguet E, Malgorn C, D'Aurelio M, Galvan L, Petit F, Benhaim L, Guillermier M, Houitte D, Dufour N, Hantraye P, Canals JM, Alberch J, Delzescaux T, Déglon N, ... ... Brouillet E, et al. A role of mitochondrial complex II defects in genetic models of Huntington's disease expressing N-terminal fragments of mutant huntingtin. Human Molecular Genetics. 22: 3869-82. PMID 23720495 DOI: 10.1093/Hmg/Ddt242 |
0.702 |
|
| 2013 |
Charbord J, Poydenot P, Bonnefond C, Feyeux M, Casagrande F, Brinon B, Francelle L, Aurégan G, Guillermier M, Cailleret M, Viegas P, Nicoleau C, Martinat C, Brouillet E, Cattaneo E, et al. High throughput screening for inhibitors of REST in neural derivatives of human embryonic stem cells reveals a chemical compound that promotes expression of neuronal genes. Stem Cells (Dayton, Ohio). 31: 1816-28. PMID 23712629 DOI: 10.1002/Stem.1430 |
0.757 |
|
| 2012 |
Delzor A, Dufour N, Petit F, Guillermier M, Houitte D, Auregan G, Brouillet E, Hantraye P, Déglon N. Restricted transgene expression in the brain with cell-type specific neuronal promoters. Human Gene Therapy Methods. 23: 242-54. PMID 22934828 DOI: 10.1089/Hgtb.2012.073 |
0.446 |
|
| 2012 |
Chaumeil MM, Valette J, Baligand C, Brouillet E, Hantraye P, Bloch G, Gaura V, Rialland A, Krystkowiak P, Verny C, Damier P, Remy P, Bachoud-Levi AC, Carlier P, Lebon V. pH as a biomarker of neurodegeneration in Huntington's disease: a translational rodent-human MRS study. Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism. 32: 771-9. PMID 22373643 DOI: 10.1038/Jcbfm.2012.15 |
0.303 |
|
| 2012 |
Galvan L, Lepejová N, Gaillard MC, Malgorn C, Guillermier M, Houitte D, Bonvento G, Petit F, Dufour N, Héry P, Gérard M, Elalouf JM, Déglon N, Brouillet E, de Chaldée M. Capucin does not modify the toxicity of a mutant Huntingtin fragment in vivo. Neurobiology of Aging. 33: 1845.e5-6. PMID 22365050 DOI: 10.1016/J.Neurobiolaging.2012.01.009 |
0.469 |
|
| 2012 |
Mochel F, Durant B, Meng X, O'Callaghan J, Yu H, Brouillet E, Wheeler VC, Humbert S, Schiffmann R, Durr A. Early alterations of brain cellular energy homeostasis in Huntington disease models. The Journal of Biological Chemistry. 287: 1361-70. PMID 22123819 DOI: 10.1074/Jbc.M111.309849 |
0.396 |
|
| 2011 |
Shin M, Jan C, Jacquard C, Jarraya B, Callebert J, Launay JM, Hantraye P, Remy P, Palfi S, Brouillet E. Chronic systemic treatment with a high-dose proteasome inhibitor in mice produces akinesia unrelated to nigrostriatal degeneration. Neurobiology of Aging. 32: 2100-2. PMID 20018410 DOI: 10.1016/J.Neurobiolaging.2009.11.015 |
0.364 |
|
| 2010 |
Faideau M, Kim J, Cormier K, Gilmore R, Welch M, Auregan G, Dufour N, Guillermier M, Brouillet E, Hantraye P, Déglon N, Ferrante RJ, Bonvento G. In vivo expression of polyglutamine-expanded huntingtin by mouse striatal astrocytes impairs glutamate transport: a correlation with Huntington's disease subjects. Human Molecular Genetics. 19: 3053-67. PMID 20494921 DOI: 10.1093/Hmg/Ddq212 |
0.447 |
|
| 2010 |
Escartin C, Brouillet E. The Nrf2 pathway as a potential therapeutic target for Huntington disease A commentary on "Triterpenoids CDDO-ethyl amide and CDDO-trifluoroethyl amide improve the behavioral phenotype and brain pathology in a transgenic mouse model of Huntington disease". Free Radical Biology & Medicine. 49: 144-6. PMID 20399852 DOI: 10.1016/J.Freeradbiomed.2010.04.009 |
0.393 |
|
| 2010 |
Alves S, Nascimento-Ferreira I, Dufour N, Hassig R, Auregan G, Nóbrega C, Brouillet E, Hantraye P, Pedroso de Lima MC, Déglon N, de Almeida LP. Silencing ataxin-3 mitigates degeneration in a rat model of Machado-Joseph disease: no role for wild-type ataxin-3? Human Molecular Genetics. 19: 2380-94. PMID 20308049 DOI: 10.1093/Hmg/Ddq111 |
0.385 |
|
| 2010 |
Cleren C, Calingasan NY, Starkov A, Jacquard C, Chen J, Brouillet E, Beal MF. Promethazine protects against 3-nitropropionic acid-induced neurotoxicity. Neurochemistry International. 56: 208-12. PMID 19852992 DOI: 10.1016/J.Neuint.2009.10.006 |
0.555 |
|
| 2010 |
Damiano M, Galvan L, Déglon N, Brouillet E. Mitochondria in Huntington's disease. Biochimica Et Biophysica Acta. 1802: 52-61. PMID 19682570 DOI: 10.1016/J.Bbadis.2009.07.012 |
0.686 |
|
| 2009 |
Jarraya B, Boulet S, Ralph GS, Jan C, Bonvento G, Azzouz M, Miskin JE, Shin M, Delzescaux T, Drouot X, Hérard AS, Day DM, Brouillet E, Kingsman SM, Hantraye P, et al. Dopamine gene therapy for Parkinson's disease in a nonhuman primate without associated dyskinesia. Science Translational Medicine. 1: 2ra4. PMID 20368163 DOI: 10.1126/Scitranslmed.3000130 |
0.434 |
|
| 2009 |
Drouet V, Perrin V, Hassig R, Dufour N, Auregan G, Alves S, Bonvento G, Brouillet E, Luthi-Carter R, Hantraye P, Déglon N. Sustained effects of nonallele-specific Huntingtin silencing. Annals of Neurology. 65: 276-85. PMID 19334076 DOI: 10.1002/Ana.21569 |
0.387 |
|
| 2009 |
Diguet E, Petit F, Escartin C, Cambon K, Bizat N, Dufour N, Hantraye P, Déglon N, Brouillet E. Normal aging modulates the neurotoxicity of mutant huntingtin. Plos One. 4: e4637. PMID 19247483 DOI: 10.1371/Journal.Pone.0004637 |
0.403 |
|
| 2009 |
Bernay B, Gaillard MC, Guryca V, Emadali A, Kuhn L, Bertrand A, Detraz I, Carcenac C, Savasta M, Brouillet E, Garin J, Elalouf JM. Discovering new bioactive neuropeptides in the striatum secretome using in vivo microdialysis and versatile proteomics. Molecular & Cellular Proteomics : McP. 8: 946-58. PMID 19164277 DOI: 10.1074/Mcp.M800501-Mcp200 |
0.349 |
|
| 2009 |
Sagredo O, González S, Aroyo I, Pazos MR, Benito C, Lastres-Becker I, Romero JP, Tolón RM, Mechoulam R, Brouillet E, Romero J, Fernández-Ruiz J. Cannabinoid CB2 receptor agonists protect the striatum against malonate toxicity: relevance for Huntington's disease. Glia. 57: 1154-67. PMID 19115380 DOI: 10.1002/Glia.20838 |
0.37 |
|
| 2009 |
Perrin V, Dufour N, Raoul C, Hassig R, Brouillet E, Aebischer P, Luthi-Carter R, Déglon N. Implication of the JNK pathway in a rat model of Huntington's disease. Experimental Neurology. 215: 191-200. PMID 19022249 DOI: 10.1016/J.Expneurol.2008.10.008 |
0.424 |
|
| 2009 |
Colin A, Faideau M, Dufour N, Auregan G, Hassig R, Andrieu T, Brouillet E, Hantraye P, Bonvento G, Déglon N. Engineered lentiviral vector targeting astrocytes in vivo. Glia. 57: 667-79. PMID 18942755 DOI: 10.1002/Glia.20795 |
0.4 |
|
| 2009 |
Galvan L, Brouillet E. Rhes, a protein with selective expression in the striatum, plays a major role in Huntington's disease pathogenesis Future Neurology. 4: 697-701. DOI: 10.2217/Fnl.09.46 |
0.435 |
|
| 2008 |
Alves S, Nascimento-Ferreira I, Auregan G, Hassig R, Dufour N, Brouillet E, Pedroso de Lima MC, Hantraye P, Pereira de Almeida L, Déglon N. Allele-specific RNA silencing of mutant ataxin-3 mediates neuroprotection in a rat model of Machado-Joseph disease. Plos One. 3: e3341. PMID 18841197 DOI: 10.1371/Journal.Pone.0003341 |
0.365 |
|
| 2008 |
Alves S, Régulier E, Nascimento-Ferreira I, Hassig R, Dufour N, Koeppen A, Carvalho AL, Simões S, de Lima MC, Brouillet E, Gould VC, Déglon N, de Almeida LP. Striatal and nigral pathology in a lentiviral rat model of Machado-Joseph disease. Human Molecular Genetics. 17: 2071-83. PMID 18385100 DOI: 10.1093/Hmg/Ddn106 |
0.463 |
|
| 2008 |
Charvin D, Roze E, Perrin V, Deyts C, Betuing S, Pagès C, Régulier E, Luthi-Carter R, Brouillet E, Déglon N, Caboche J. Haloperidol protects striatal neurons from dysfunction induced by mutated huntingtin in vivo. Neurobiology of Disease. 29: 22-9. PMID 17905594 DOI: 10.1016/J.Nbd.2007.07.028 |
0.457 |
|
| 2007 |
Escartin C, Boyer F, Bemelmans AP, Hantraye P, Brouillet E. IGF-1 exacerbates the neurotoxicity of the mitochondrial inhibitor 3NP in rats. Neuroscience Letters. 425: 167-72. PMID 17868993 DOI: 10.1016/J.Neulet.2007.08.031 |
0.439 |
|
| 2007 |
Escartin C, Pierre K, Colin A, Brouillet E, Delzescaux T, Guillermier M, Dhenain M, Déglon N, Hantraye P, Pellerin L, Bonvento G. Activation of astrocytes by CNTF induces metabolic plasticity and increases resistance to metabolic insults. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 27: 7094-104. PMID 17611262 DOI: 10.1523/Jneurosci.0174-07.2007 |
0.396 |
|
| 2007 |
GarcÃa-MartÃnez JM, Pérez-Navarro E, Xifró X, Canals JM, DÃaz-Hernández M, Trioulier Y, Brouillet E, Lucas JJ, Alberch J. BH3-only proteins Bid and Bim(EL) are differentially involved in neuronal dysfunction in mouse models of Huntington's disease. Journal of Neuroscience Research. 85: 2756-69. PMID 17387706 DOI: 10.1002/Jnr.21258 |
0.41 |
|
| 2006 |
Escartin C, Brouillet E, Gubellini P, Trioulier Y, Jacquard C, Smadja C, Knott GW, Kerkerian-Le Goff L, Déglon N, Hantraye P, Bonvento G. Ciliary neurotrophic factor activates astrocytes, redistributes their glutamate transporters GLAST and GLT-1 to raft microdomains, and improves glutamate handling in vivo. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 26: 5978-89. PMID 16738240 DOI: 10.1523/Jneurosci.0302-06.2006 |
0.394 |
|
| 2006 |
Arango M, Holbert S, Zala D, Brouillet E, Pearson J, Régulier E, Thakur AK, Aebischer P, Wetzel R, Déglon N, Néri C. CA150 expression delays striatal cell death in overexpression and knock-in conditions for mutant huntingtin neurotoxicity. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 26: 4649-59. PMID 16641246 DOI: 10.1523/Jneurosci.5409-05.2006 |
0.365 |
|
| 2006 |
Borrell-Pagès M, Canals JM, Cordelières FP, Parker JA, Pineda JR, Grange G, Bryson EA, Guillermier M, Hirsch E, Hantraye P, Cheetham ME, Néri C, Alberch J, Brouillet E, Saudou F, et al. Cystamine and cysteamine increase brain levels of BDNF in Huntington disease via HSJ1b and transglutaminase. The Journal of Clinical Investigation. 116: 1410-24. PMID 16604191 DOI: 10.1172/Jci27607 |
0.397 |
|
| 2006 |
Jacquard C, Trioulier Y, Cosker F, Escartin C, Bizat N, Hantraye P, Cancela JM, Bonvento G, Brouillet E. Brain mitochondrial defects amplify intracellular [Ca2+] rise and neurodegeneration but not Ca2+ entry during NMDA receptor activation. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 20: 1021-3. PMID 16571773 DOI: 10.1096/Fj.05-5085Fje |
0.378 |
|
| 2005 |
Brouillet E, Jacquard C, Bizat N, Blum D. 3-Nitropropionic acid: a mitochondrial toxin to uncover physiopathological mechanisms underlying striatal degeneration in Huntington's disease. Journal of Neurochemistry. 95: 1521-40. PMID 16300642 DOI: 10.1111/j.1471-4159.2005.03515.x |
0.343 |
|
| 2005 |
Zala D, Benchoua A, Brouillet E, Perrin V, Gaillard MC, Zurn AD, Aebischer P, Déglon N. Progressive and selective striatal degeneration in primary neuronal cultures using lentiviral vector coding for a mutant huntingtin fragment. Neurobiology of Disease. 20: 785-98. PMID 16006135 DOI: 10.1016/J.Nbd.2005.05.017 |
0.442 |
|
| 2005 |
Bantubungi K, Jacquard C, Greco A, Pintor A, Chtarto A, Tai K, Galas MC, Tenenbaum L, Déglon N, Popoli P, Minghetti L, Brouillet E, Brotchi J, Levivier M, Schiffmann SN, et al. Minocycline in phenotypic models of Huntington's disease. Neurobiology of Disease. 18: 206-17. PMID 15649711 DOI: 10.1016/j.nbd.2004.09.017 |
0.336 |
|
| 2005 |
Deglon N, Zala D, Benchoua A, Aebischer P, Zurn AD, Brouillet E. 953. Progressive and Selective Striatal Degeneration in Primary Neuronal Cultures Using Lentiviral Vector Coding Mutant Huntingtin Fragment Molecular Therapy. 11. DOI: 10.1016/J.Ymthe.2005.07.496 |
0.44 |
|
| 2004 |
Lastres-Becker I, Bizat N, Boyer F, Hantraye P, Fernández-Ruiz J, Brouillet E. Potential involvement of cannabinoid receptors in 3-nitropropionic acid toxicity in vivo. Neuroreport. 15: 2375-9. PMID 15640759 DOI: 10.1097/00001756-200410250-00015 |
0.373 |
|
| 2004 |
Yang L, Sugama S, Mischak RP, Kiaei M, Bizat N, Brouillet E, Joh TH, Beal MF. A novel systemically active caspase inhibitor attenuates the toxicities of MPTP, malonate, and 3NP in vivo. Neurobiology of Disease. 17: 250-9. PMID 15474362 DOI: 10.1016/J.Nbd.2004.07.021 |
0.702 |
|
| 2004 |
Escartin C, Boyer F, Bemelmans AP, Hantraye P, Brouillet E. Insulin growth factor-1 protects against excitotoxicity in the rat striatum. Neuroreport. 15: 2251-4. PMID 15371744 DOI: 10.1097/00001756-200410050-00022 |
0.351 |
|
| 2004 |
Galas MC, Bizat N, Cuvelier L, Bantubungi K, Brouillet E, Schiffmann SN, Blum D. Death of cortical and striatal neurons induced by mitochondrial defect involves differential molecular mechanisms. Neurobiology of Disease. 15: 152-9. PMID 14751780 DOI: 10.1016/j.nbd.2003.09.013 |
0.308 |
|
| 2003 |
Lastres-Becker I, Bizat N, Boyer F, Hantraye P, Brouillet E, Fernández-Ruiz J. Effects of cannabinoids in the rat model of Huntington's disease generated by an intrastriatal injection of malonate. Neuroreport. 14: 813-6. PMID 12858038 DOI: 10.1097/00001756-200305060-00007 |
0.412 |
|
| 2003 |
de Chaldée M, Gaillard MC, Bizat N, Buhler JM, Manzoni O, Bockaert J, Hantraye P, Brouillet E, Elalouf JM. Quantitative assessment of transcriptome differences between brain territories. Genome Research. 13: 1646-53. PMID 12840043 DOI: 10.1101/Gr.1173403 |
0.321 |
|
| 2003 |
Bizat N, Hermel JM, Boyer F, Jacquard C, Créminon C, Ouary S, Escartin C, Hantraye P, Kajewski S, Brouillet E. Calpain is a major cell death effector in selective striatal degeneration induced in vivo by 3-nitropropionate: implications for Huntington's disease. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 23: 5020-30. PMID 12832525 DOI: 10.1523/Jneurosci.23-12-05020.2003 |
0.421 |
|
| 2002 |
Henry PG, Lebon V, Vaufrey F, Brouillet E, Hantraye P, Bloch G. Decreased TCA cycle rate in the rat brain after acute 3-NP treatment measured by in vivo 1H-[13C] NMR spectroscopy. Journal of Neurochemistry. 82: 857-66. PMID 12358791 DOI: 10.1046/J.1471-4159.2002.01006.X |
0.307 |
|
| 2002 |
Mittoux V, Ouary S, Monville C, Lisovoski F, Poyot T, Conde F, Escartin C, Robichon R, Brouillet E, Peschanski M, Hantraye P. Corticostriatopallidal neuroprotection by adenovirus-mediated ciliary neurotrophic factor gene transfer in a rat model of progressive striatal degeneration. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 22: 4478-86. PMID 12040055 DOI: 10.1523/Jneurosci.22-11-04478.2002 |
0.408 |
|
| 2002 |
Garcia M, Vanhoutte P, Pages C, Besson MJ, Brouillet E, Caboche J. The mitochondrial toxin 3-nitropropionic acid induces striatal neurodegeneration via a c-Jun N-terminal kinase/c-Jun module. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 22: 2174-84. PMID 11896157 DOI: 10.1523/Jneurosci.22-06-02174.2002 |
0.43 |
|
| 2000 |
Mittoux V, Joseph JM, Conde F, Palfi S, Dautry C, Poyot T, Bloch J, Deglon N, Ouary S, Nimchinsky EA, Brouillet E, Hof PR, Peschanski M, Aebischer P, Hantraye P. Restoration of cognitive and motor functions by ciliary neurotrophic factor in a primate model of Huntington's disease. Human Gene Therapy. 11: 1177-87. PMID 10834619 DOI: 10.1089/10430340050015220 |
0.427 |
|
| 2000 |
Dautry C, Vaufrey F, Brouillet E, Bizat N, Henry PG, Condé F, Bloch G, Hantraye P. Early N-acetylaspartate depletion is a marker of neuronal dysfunction in rats and primates chronically treated with the mitochondrial toxin 3-nitropropionic acid. Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism. 20: 789-99. PMID 10826529 DOI: 10.1097/00004647-200005000-00005 |
0.428 |
|
| 2000 |
Kowall NW, Hantraye P, Brouillet E, Beal MF, McKee AC, Ferrante RJ. MPTP induces alpha-synuclein aggregation in the substantia nigra of baboons. Neuroreport. 11: 211-3. PMID 10683860 DOI: 10.1097/00001756-200001170-00041 |
0.485 |
|
| 1999 |
Brouillet E, Condé F, Beal MF, Hantraye P. Replicating Huntington's disease phenotype in experimental animals. Progress in Neurobiology. 59: 427-68. PMID 10515664 DOI: 10.1016/S0301-0082(99)00005-2 |
0.597 |
|
| 1999 |
Dautry C, Condé F, Brouillet E, Mittoux V, Beal MF, Bloch G, Hantraye P. Serial 1H-NMR spectroscopy study of metabolic impairment in primates chronically treated with the succinate dehydrogenase inhibitor 3-nitropropionic acid. Neurobiology of Disease. 6: 259-68. PMID 10448053 DOI: 10.1006/Nbdi.1999.0244 |
0.533 |
|
| 1999 |
Ferrante RJ, Hantraye P, Brouillet E, Beal MF. Increased nitrotyrosine immunoreactivity in substantia nigra neurons in MPTP treated baboons is blocked by inhibition of neuronal nitric oxide synthase. Brain Research. 823: 177-82. PMID 10095024 DOI: 10.1016/S0006-8993(99)01166-X |
0.563 |
|
| 1998 |
Palfi S, Condé F, Riche D, Brouillet E, Dautry C, Mittoux V, Chibois A, Peschanski M, Hantraye P. Fetal striatal allografts reverse cognitive deficits in a primate model of Huntington disease. Nature Medicine. 4: 963-6. PMID 9701252 DOI: 10.1038/Nm0898-963 |
0.382 |
|
| 1998 |
Brouillet E, Guyot MC, Mittoux V, Altairac S, Condé F, Palfi S, Hantraye P. Partial inhibition of brain succinate dehydrogenase by 3-nitropropionic acid is sufficient to initiate striatal degeneration in rat. Journal of Neurochemistry. 70: 794-805. PMID 9453576 DOI: 10.1046/J.1471-4159.1998.70020794.X |
0.397 |
|
| 1997 |
Guyot MC, Palfi S, Stutzmann JM, Mazière M, Hantraye P, Brouillet E. Riluzole protects from motor deficits and striatal degeneration produced by systemic 3-nitropropionic acid intoxication in rats. Neuroscience. 81: 141-9. PMID 9300407 DOI: 10.1016/S0306-4522(97)00192-9 |
0.365 |
|
| 1997 |
Palfi S, Riche D, Brouillet E, Guyot MC, Mary V, Wahl F, Peschanski M, Stutzmann JM, Hantraye P. Riluzole reduces incidence of abnormal movements but not striatal cell death in a primate model of progressive striatal degeneration. Experimental Neurology. 146: 135-41. PMID 9225746 DOI: 10.1006/Exnr.1997.6520 |
0.382 |
|
| 1997 |
Guyot MC, Hantraye P, Dolan R, Palfi S, Maziére M, Brouillet E. Quantifiable bradykinesia, gait abnormalities and Huntington's disease-like striatal lesions in rats chronically treated with 3-nitropropionic acid. Neuroscience. 79: 45-56. PMID 9178864 DOI: 10.1016/S0306-4522(96)00602-1 |
0.319 |
|
| 1996 |
Hantraye P, Brouillet E, Ferrante R, Palfi S, Dolan R, Matthews RT, Beal MF. Inhibition of neuronal nitric oxide synthase prevents MPTP-induced parkinsonism in baboons. Nature Medicine. 2: 1017-21. PMID 8782460 DOI: 10.1038/nm0996-1017 |
0.51 |
|
| 1996 |
Palfi S, Ferrante RJ, Brouillet E, Beal MF, Dolan R, Guyot MC, Peschanski M, Hantraye P. Chronic 3-nitropropionic acid treatment in baboons replicates the cognitive and motor deficits of Huntington's disease. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 16: 3019-25. PMID 8622131 DOI: 10.1523/Jneurosci.16-09-03019.1996 |
0.527 |
|
| 1996 |
Jenkins BG, Brouillet E, Chen YC, Storey E, Schulz JB, Kirschner P, Beal MF, Rosen BR. Non-invasive neurochemical analysis of focal excitotoxic lesions in models of neurodegenerative illness using spectroscopic imaging. Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism. 16: 450-61. PMID 8621749 DOI: 10.1097/00004647-199605000-00011 |
0.664 |
|
| 1995 |
Brouillet E, Hantraye P. Effects of chronic MPTP and 3-nitropropionic acid in nonhuman primates. Current Opinion in Neurology. 8: 469-73. PMID 8845934 DOI: 10.1097/00019052-199512000-00014 |
0.389 |
|
| 1995 |
Brouillet E, Hantraye P, Ferrante RJ, Dolan R, Leroy-Willig A, Kowall NW, Beal MF. Chronic mitochondrial energy impairment produces selective striatal degeneration and abnormal choreiform movements in primates. Proceedings of the National Academy of Sciences of the United States of America. 92: 7105-9. PMID 7624378 DOI: 10.1073/Pnas.92.15.7105 |
0.596 |
|
| 1994 |
Brouillet E, Henshaw DR, Schulz JB, Beal MF. Aminooxyacetic acid striatal lesions attenuated by 1,3-butanediol and coenzyme Q10. Neuroscience Letters. 177: 58-62. PMID 7824183 DOI: 10.1016/0304-3940(94)90044-2 |
0.554 |
|
| 1994 |
Brouillet E, Hyman BT, Jenkins BG, Henshaw DR, Schulz JB, Sodhi P, Rosen BR, Beal MF. Systemic or local administration of azide produces striatal lesions by an energy impairment-induced excitotoxic mechanism. Experimental Neurology. 129: 175-82. PMID 7525331 DOI: 10.1006/Exnr.1994.1159 |
0.555 |
|
| 1993 |
Brouillet E, Beal MF. NMDA antagonists partially protect against MPTP induced neurotoxicity in mice. Neuroreport. 4: 387-90. PMID 8499594 DOI: 10.1097/00001756-199304000-00011 |
0.454 |
|
| 1993 |
Brouillet EP, Shinobu L, McGarvey U, Hochberg F, Beal MF. Manganese injection into the rat striatum produces excitotoxic lesions by impairing energy metabolism. Experimental Neurology. 120: 89-94. PMID 8477830 DOI: 10.1006/exnr.1993.1042 |
0.74 |
|
| 1993 |
Brouillet E, Jenkins BG, Hyman BT, Ferrante RJ, Kowall NW, Srivastava R, Roy DS, Rosen BR, Beal MF. Age-dependent vulnerability of the striatum to the mitochondrial toxin 3-nitropropionic acid. Journal of Neurochemistry. 60: 356-9. PMID 8417157 DOI: 10.1111/J.1471-4159.1993.Tb05859.X |
0.502 |
|
| 1993 |
Srivastava R, Brouillet E, Beal MF, Storey E, Hyman BT. Blockade of 1-methyl-4-phenylpyridinium ion (MPP+) nigral toxicity in the rat by prior decortication or MK-801 treatment: a stereological estimate of neuronal loss. Neurobiology of Aging. 14: 295-301. PMID 8103573 DOI: 10.1016/0197-4580(93)90114-Q |
0.623 |
|
| 1993 |
Beal MF, Brouillet E, Jenkins BG, Ferrante RJ, Kowall NW, Miller JM, Storey E, Srivastava R, Rosen BR, Hyman BT. Neurochemical and histologic characterization of striatal excitotoxic lesions produced by the mitochondrial toxin 3-nitropropionic acid. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 13: 4181-92. PMID 7692009 |
0.636 |
|
| 1993 |
Beal MF, Brouillet E, Jenkins B, Henshaw R, Rosen B, Hyman BT. Age-dependent striatal excitotoxic lesions produced by the endogenous mitochondrial inhibitor malonate. Journal of Neurochemistry. 61: 1147-50. PMID 7689641 DOI: 10.1111/J.1471-4159.1993.Tb03633.X |
0.571 |
|
| 1993 |
Beal M, Brouillet E, Jenkins B, Ferrante R, Kowall N, Miller J, Storey E, Srivastava R, Rosen B, Hyman B. Neurochemical and histologic characterization of striatal excitotoxic lesions produced by the mitochondrial toxin 3-nitropropionic acid The Journal of Neuroscience. 13: 4181-4192. DOI: 10.1523/Jneurosci.13-10-04181.1993 |
0.766 |
|
| 1992 |
Storey E, Hyman BT, Jenkins B, Brouillet E, Miller JM, Rosen BR, Beal MF. 1-Methyl-4-phenylpyridinium produces excitotoxic lesions in rat striatum as a result of impairment of oxidative metabolism. Journal of Neurochemistry. 58: 1975-8. PMID 1560246 DOI: 10.1111/J.1471-4159.1992.Tb10080.X |
0.648 |
|
| 1990 |
Yamaguchi T, Kunimoto M, Pappata S, Chavoix C, Brouillet E, Riche D, Mazière M, Naquet R, MacKenzie ET, Baron JC. Effects of unilateral lesion of the nucleus basalis of Meynert on brain glucose utilization in callosotomized baboons: a PET study. Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism. 10: 618-23. PMID 2384534 DOI: 10.1038/Jcbfm.1990.113 |
0.302 |
|
| Low-probability matches (unlikely to be authored by this person) |
| 2003 |
Blum D, Galas MC, Pintor A, Brouillet E, Ledent C, Muller CE, Bantubungi K, Galluzzo M, Gall D, Cuvelier L, Rolland AS, Popoli P, Schiffmann SN. A dual role of adenosine A2A receptors in 3-nitropropionic acid-induced striatal lesions: implications for the neuroprotective potential of A2A antagonists. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 23: 5361-9. PMID 12832562 |
0.297 |
|
| 2015 |
Roy M, Cardoso C, Dorieux O, Malgorn C, Epelbaum S, Petit F, Kraska A, Brouillet E, Delatour B, Perret M, Aujard F, Dhenain M. Age-associated evolution of plasmatic amyloid in mouse lemur primates: relationship with intracellular amyloid deposition. Neurobiology of Aging. 36: 149-56. PMID 25131002 DOI: 10.1016/J.Neurobiolaging.2014.07.017 |
0.295 |
|
| 1992 |
Varastet M, Brouillet E, Chavoix C, Prenant C, Crouzel C, Stulzaft O, Bottlaender M, Cayla J, Mazière B, Mazière M. In vivo visualization of central muscarinic receptors using [11C]quinuclidinyl benzilate and positron emission tomography in baboons. European Journal of Pharmacology. 213: 275-84. PMID 1521561 DOI: 10.1016/0014-2999(92)90692-W |
0.294 |
|
| 2023 |
Duwat C, Léal P, Vautheny A, Aurégan G, Joséphine C, Gaillard MC, Hérard AS, Jan C, Gipchtein P, Mitja J, Fouquet S, Niepon ML, Hantraye P, Brouillet E, Bonvento G, et al. Development of an AAV-based model of tauopathy targeting retinal ganglion cells and the mouse visual pathway to study the role of microglia in Tau pathology. Neurobiology of Disease. 106116. PMID 37054900 DOI: 10.1016/j.nbd.2023.106116 |
0.294 |
|
| 2016 |
Palombo M, Ligneul C, Najac C, Le Douce J, Flament J, Escartin C, Hantraye P, Brouillet E, Bonvento G, Valette J. New paradigm to assess brain cell morphology by diffusion-weighted MR spectroscopy in vivo. Proceedings of the National Academy of Sciences of the United States of America. PMID 27226303 DOI: 10.1073/Pnas.1504327113 |
0.292 |
|
| 1999 |
Brouillet E, Trembleau A, Galanaud D, Volovitch M, Bouillot C, Valenza C, Prochiantz A, Allinquant B. The amyloid precursor protein interacts with Go heterotrimeric protein within a cell compartment specialized in signal transduction. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 19: 1717-27. PMID 10024358 DOI: 10.1523/Jneurosci.19-05-01717.1999 |
0.292 |
|
| 1991 |
de la Sayette V, Chavoix C, Brouillet E, Hantraye P, Kunimoto M, Khalili-Varasteh M, Guibert B, Prenant C, Mazière M. In vivo benzodiazepine receptor occupancy by CL 218,872 visualized by positron emission tomography in the brain of the living baboon: modulation by GABAergic transmission and relation with anticonvulsant activity. Experimental Brain Research. 83: 397-402. PMID 1673661 DOI: 10.1007/Bf00231164 |
0.291 |
|
| 1994 |
Bottlaender M, Brouillet E, Varastet M, Le Breton C, Schmid L, Fuseau C, Sitbon R, Crouzel C, Mazière M. In vivo high intrinsic efficacy of triazolam: a positron emission tomography study in nonhuman primates. Journal of Neurochemistry. 62: 1102-11. PMID 8113798 DOI: 10.1046/J.1471-4159.1994.62031102.X |
0.29 |
|
| 1988 |
Chavoix C, Hantraye P, Brouillet E, Guibert B, Fukuda H, De la Sayette V, Fournier D, Naquet R, Mazière M. Status epilepticus induced by pentylenetetrazole modulates in vivo [11C]Ro 15-1788 binding to benzodiazepine receptors. Effects of ligands acting at the supramolecular receptor complex. European Journal of Pharmacology. 146: 207-14. PMID 2836206 DOI: 10.1016/0014-2999(88)90294-4 |
0.289 |
|
| 2008 |
Benchoua A, Trioulier Y, Diguet E, Malgorn C, Gaillard MC, Dufour N, Elalouf JM, Krajewski S, Hantraye P, Déglon N, Brouillet E. Dopamine determines the vulnerability of striatal neurons to the N-terminal fragment of mutant huntingtin through the regulation of mitochondrial complex II. Human Molecular Genetics. 17: 1446-56. PMID 18267960 DOI: 10.1093/hmg/ddn033 |
0.288 |
|
| 2022 |
Pérot JB, Célestine M, Palombo M, Dhenain M, Humbert S, Brouillet E, Flament J. Longitudinal multimodal MRI characterization of a knock-in mouse model of Huntington's disease reveals early grey and white matter alterations. Human Molecular Genetics. PMID 35147158 DOI: 10.1093/hmg/ddac036 |
0.284 |
|
| 1991 |
Brouillet E, Chavoix C, Bottlaender M, Khalili-Varasteh M, Hantraye P, Fournier D, Dodd RH, Mazière M. In vivo bidirectional modulatory effect of benzodiazepine receptor ligands on GABAergic transmission evaluated by positron emission tomography in non-human primates. Brain Research. 557: 167-76. PMID 1660750 DOI: 10.1016/0006-8993(91)90131-E |
0.283 |
|
| 2009 |
Chaumeil MM, Valette J, Guillermier M, Brouillet E, Boumezbeur F, Herard AS, Bloch G, Hantraye P, Lebon V. Multimodal neuroimaging provides a highly consistent picture of energy metabolism, validating 31P MRS for measuring brain ATP synthesis. Proceedings of the National Academy of Sciences of the United States of America. 106: 3988-93. PMID 19234118 DOI: 10.1073/Pnas.0806516106 |
0.281 |
|
| 2008 |
Brochier C, Gaillard MC, Diguet E, Caudy N, Dossat C, Ségurens B, Wincker P, Roze E, Caboche J, Hantraye P, Brouillet E, Elalouf JM, de Chaldée M. Quantitative gene expression profiling of mouse brain regions reveals differential transcripts conserved in human and affected in disease models. Physiological Genomics. 33: 170-9. PMID 18252803 DOI: 10.1152/physiolgenomics.00125.2007 |
0.279 |
|
| 1997 |
Bottlaender M, Schmid L, Fuseau C, Fournier D, Brouillet E, Mazière M. In vivo modulation of benzodiazepine receptor function after inhibition of endogenous gamma-aminobutyyric acid synthesis. European Journal of Pharmacology. 321: 13-7. PMID 9083780 DOI: 10.1016/S0014-2999(97)00004-6 |
0.279 |
|
| 2005 |
Bizat N, Galas MC, Jacquard C, Boyer F, Hermel JM, Schiffmann SN, Hantraye P, Blum D, Brouillet E. Neuroprotective effect of zVAD against the neurotoxin 3-nitropropionic acid involves inhibition of calpain. Neuropharmacology. 49: 695-702. PMID 15998526 DOI: 10.1016/j.neuropharm.2005.04.030 |
0.273 |
|
| 1991 |
Chavoix C, Brouillet E, Kunimoto M, De la Sayette V, Khalili-Varasteh M, Hantraye P, Dodd RH, Guibert B, Prenant C, Naquet R. Relationships between benzodiazepine receptors, impairment of GABAergic transmission and convulsant activity of beta-CCM: a PET study in the baboon Papio papio. Epilepsy Research. 8: 1-10. PMID 1647949 DOI: 10.1016/0920-1211(91)90030-J |
0.271 |
|
| 2021 |
Vautheny A, Duwat C, Auregan G, Joséphine C, Hérard AS, Jan C, Mitja J, Gipchtein P, Gaillard MC, Buée L, Blum D, Hantraye P, Bonvento G, Brouillet E, Cambon K, et al. THY-Tau22 mouse model accumulates more tauopathy at late stage of the disease in response to microglia deactivation through TREM2 deficiency. Neurobiology of Disease. 105398. PMID 34019997 DOI: 10.1016/j.nbd.2021.105398 |
0.27 |
|
| 2000 |
Brouillet E. Animal models of Huntington's disease: from basic research on neuronal death to assessment of new therapeutic strategies. Functional Neurology. 15: 239-51. PMID 11213527 |
0.27 |
|
| 1995 |
Schmid L, Bottlaender M, Fuseau C, Fournier D, Brouillet E, Mazière M. Zolpidem displays heterogeneity in its binding to the nonhuman primate benzodiazepine receptor in vivo. Journal of Neurochemistry. 65: 1880-6. PMID 7561888 DOI: 10.1046/J.1471-4159.1995.65041880.X |
0.269 |
|
| 2021 |
Maté de Gérando A, d'Orange M, Augustin E, Joséphine C, Aurégan G, Gaudin-Guérif M, Guillermier M, Hérard AS, Stimmer L, Petit F, Gipchtein P, Jan C, Escartin C, Selingue E, Carvalho K, ... ... Brouillet E, et al. Neuronal tau species transfer to astrocytes and induce their loss according to tau aggregation state. Brain : a Journal of Neurology. PMID 33842937 DOI: 10.1093/brain/awab011 |
0.267 |
|
| 2006 |
Benchoua A, Trioulier Y, Zala D, Gaillard MC, Lefort N, Dufour N, Saudou F, Elalouf JM, Hirsch E, Hantraye P, Déglon N, Brouillet E. Involvement of mitochondrial complex II defects in neuronal death produced by N-terminus fragment of mutated huntingtin. Molecular Biology of the Cell. 17: 1652-63. PMID 16452635 DOI: 10.1091/Mbc.E05-07-0607 |
0.266 |
|
| 2021 |
Wiatr K, Marczak Ł, Pérot JB, Brouillet E, Flament J, Figiel M. Broad Influence of Mutant Ataxin-3 on the Proteome of the Adult Brain, Young Neurons, and Axons Reveals Central Molecular Processes and Biomarkers in SCA3/MJD Using Knock-In Mouse Model. Frontiers in Molecular Neuroscience. 14: 658339. PMID 34220448 DOI: 10.3389/fnmol.2021.658339 |
0.26 |
|
| 2021 |
Cresto N, Gardier C, Gaillard MC, Gubinelli F, Roost P, Molina D, Josephine C, Dufour N, Auregan G, Guillermier M, Bernier S, Jan C, Gipchtein P, Hantraye P, Chartier-Harlin MC, ... ... Brouillet E, et al. The C-Terminal Domain of LRRK2 with the G2019S Substitution Increases Mutant A53T α-Synuclein Toxicity in Dopaminergic Neurons In Vivo. International Journal of Molecular Sciences. 22. PMID 34201785 DOI: 10.3390/ijms22136760 |
0.255 |
|
| 1996 |
Roeda D, Crouzel C, Brouillet E, Valette H. Synthesis and in vivo distribution of no-carrier-added N(omega)-Nitro-L-arginine [11C]methyl ester, a nitric oxide synthase inhibitor. Nuclear Medicine and Biology. 23: 509-12. PMID 8832708 DOI: 10.1016/0969-8051(96)00032-7 |
0.255 |
|
| 2016 |
Tiret B, Brouillet E, Valette J. Evidence for a "metabolically inactive" inorganic phosphate pool in adenosine triphosphate synthase reaction using localized 31P saturation transfer magnetic resonance spectroscopy in the rat brain at 11.7 T. Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism. PMID 27354096 DOI: 10.1177/0271678X16657095 |
0.255 |
|
| 2007 |
Perrin V, Régulier E, Abbas-Terki T, Hassig R, Brouillet E, Aebischer P, Luthi-Carter R, Déglon N. Neuroprotection by Hsp104 and Hsp27 in lentiviral-based rat models of Huntington's disease. Molecular Therapy : the Journal of the American Society of Gene Therapy. 15: 903-11. PMID 17375066 DOI: 10.1038/mt.sj.6300141 |
0.255 |
|
| 2014 |
Dujardin S, Brouillet E, Hantraye P, Colin M, Buée L. Which Tau species are toxic? Consequences for therapeutic approaches Neurobiology of Aging. 35: S4. DOI: 10.1016/J.Neurobiolaging.2014.01.042 |
0.25 |
|
| 2014 |
Najac C, Marchadour C, Guillermier M, Houitte D, Slavov V, Brouillet E, Hantraye P, Lebon V, Valette J. Intracellular metabolites in the primate brain are primarily localized in long fibers rather than in cell bodies, as shown by diffusion-weighted magnetic resonance spectroscopy. Neuroimage. 90: 374-80. PMID 24382523 DOI: 10.1016/J.Neuroimage.2013.12.045 |
0.25 |
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| 2003 |
Stefanova N, Puschban Z, Fernagut PO, Brouillet E, Tison F, Reindl M, Jellinger KA, Poewe W, Wenning GK. Neuropathological and behavioral changes induced by various treatment paradigms with MPTP and 3-nitropropionic acid in mice: towards a model of striatonigral degeneration (multiple system atrophy). Acta Neuropathologica. 106: 157-66. PMID 12764627 DOI: 10.1007/S00401-003-0717-Y |
0.244 |
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| 1995 |
Brouillet E, Roeda D, Valette H, Fuseau C, Guyot MC, Crouzel C. In vivo metabolites of N omega-nitro-L-arginine methyl ester: methanol and N omega-nitro-L-arginine. European Journal of Pharmacology. 293: 487-90. PMID 8748703 DOI: 10.1016/0926-6917(95)90070-5 |
0.242 |
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| 2012 |
Marchadour C, Brouillet E, Hantraye P, Lebon V, Valette J. Anomalous diffusion of brain metabolites evidenced by diffusion-weighted magnetic resonance spectroscopy in vivo. Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism. 32: 2153-60. PMID 22929443 DOI: 10.1038/Jcbfm.2012.119 |
0.238 |
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| 2013 |
Aron Badin R, Spinnewyn B, Gaillard MC, Jan C, Malgorn C, Van Camp N, Dollé F, Guillermier M, Boulet S, Bertrand A, Savasta M, Auguet M, Brouillet E, Chabrier PE, Hantraye P. IRC-082451, a novel multitargeting molecule, reduces L-DOPA-induced dyskinesias in MPTP Parkinsonian primates. Plos One. 8: e52680. PMID 23300984 DOI: 10.1371/journal.pone.0052680 |
0.234 |
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| 1987 |
Hantraye P, Chavoix C, Guibert B, Fukuda H, Brouillet E, Dodd RH, Prenant C, Crouzel M, Naquet R, Mazière M. Benzodiazepine receptors studied in living primates by positron emission tomography: inverse agonist interactions. European Journal of Pharmacology. 138: 239-47. PMID 3040433 DOI: 10.1016/0014-2999(87)90438-9 |
0.233 |
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| 2018 |
Senova S, Poupon C, Dauguet J, Stewart HJ, Dugué GP, Jan C, Hosomi K, Ralph GS, Barnes L, Drouot X, Pouzat C, Mangin JF, Pain F, Doignon I, Aron-Badin R, ... Brouillet E, et al. Optogenetic Tractography for anatomo-functional characterization of cortico-subcortical neural circuits in non-human primates. Scientific Reports. 8: 3362. PMID 29463867 DOI: 10.1038/S41598-018-21486-8 |
0.227 |
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| 2022 |
Alcalá-Vida R, Lotz C, Brulé B, Seguin J, Decraene C, Awada A, Bombardier A, Cosquer B, de Vasconcelos AP, Brouillet E, Cassel JC, Boutillier AL, Merienne K. Altered activity-regulated H3K9 acetylation at TGF-beta signaling genes during egocentric memory in Huntington's disease. Progress in Neurobiology. 102363. PMID 36179935 DOI: 10.1016/j.pneurobio.2022.102363 |
0.224 |
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| 2001 |
El Massioui N, Ouary S, Chéruel F, Hantraye P, Brouillet E. Perseverative behavior underlying attentional set-shifting deficits in rats chronically treated with the neurotoxin 3-nitropropionic acid. Experimental Neurology. 172: 172-81. PMID 11681849 DOI: 10.1006/exnr.2001.7766 |
0.222 |
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| 2003 |
Bizat N, Hermel JM, Humbert S, Jacquard C, Créminon C, Escartin C, Saudou F, Krajewski S, Hantraye P, Brouillet E. In vivo calpain/caspase cross-talk during 3-nitropropionic acid-induced striatal degeneration: implication of a calpain-mediated cleavage of active caspase-3. The Journal of Biological Chemistry. 278: 43245-53. PMID 12917435 DOI: 10.1074/Jbc.M305057200 |
0.215 |
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| 2014 |
Dujardin S, Bégard S, Caillierez R, Lachaud C, Delattre L, Carrier S, Loyens A, Galas MC, Bousset L, Melki R, Aurégan G, Hantraye P, Brouillet E, Buée L, Colin M. Ectosomes: a new mechanism for non-exosomal secretion of tau protein. Plos One. 9: e100760. PMID 24971751 DOI: 10.1371/Journal.Pone.0100760 |
0.213 |
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| 1994 |
Hantraye P, Brouillet E. Chronic treatment with mitochondrial toxins in primates as experimental models of Parkinson's and Huntington's diseases Circulation Et Metabolisme Du Cerveau. 11: 311-326. |
0.207 |
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| 2021 |
Rebelo AL, Gubinelli F, Roost P, Jan C, Brouillet E, Van Camp N, Drake RR, Saldova R, Pandit A. Complete spatial characterisation of N-glycosylation upon striatal neuroinflammation in the rodent brain. Journal of Neuroinflammation. 18: 116. PMID 33993882 DOI: 10.1186/s12974-021-02163-6 |
0.207 |
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| 2007 |
Palfi S, Brouillet E, Jarraya B, Bloch J, Jan C, Shin M, Condé F, Li XJ, Aebischer P, Hantraye P, Déglon N. Expression of mutated huntingtin fragment in the putamen is sufficient to produce abnormal movement in non-human primates. Molecular Therapy : the Journal of the American Society of Gene Therapy. 15: 1444-51. PMID 17505477 DOI: 10.1038/Sj.Mt.6300185 |
0.199 |
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| 2008 |
Bantubungi K, Blum D, Cuvelier L, Wislet-Gendebien S, Rogister B, Brouillet E, Schiffmann SN. Stem cell factor and mesenchymal and neural stem cell transplantation in a rat model of Huntington's disease. Molecular and Cellular Neurosciences. 37: 454-70. PMID 18083596 DOI: 10.1016/j.mcn.2007.11.001 |
0.195 |
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| 2022 |
Kelly R, Bemelmans AP, Joséphine C, Brouillet E, McKernan DP, Dowd E. Time-Course of Alterations in the Endocannabinoid System after Viral-Mediated Overexpression of α-Synuclein in the Rat Brain. Molecules (Basel, Switzerland). 27. PMID 35056822 DOI: 10.3390/molecules27020507 |
0.194 |
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| 2021 |
Kelly R, Cairns AG, Ådén J, Almqvist F, Bemelmans AP, Brouillet E, Patton T, McKernan DP, Dowd E. The Small Molecule Alpha-Synuclein Aggregator, FN075, Enhances Alpha-Synuclein Pathology in Subclinical AAV Rat Models. Biomolecules. 11. PMID 34827685 DOI: 10.3390/biom11111685 |
0.194 |
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| 1993 |
Wüllner U, Brouillet E, Isacson O, Young AB, Penney JB. Glutamate receptor binding sites in MPTP-treated mice. Experimental Neurology. 121: 284-7. PMID 8393409 DOI: 10.1006/exnr.1993.1098 |
0.19 |
|
| 1990 |
Brouillet E, Chavoix C, Hantraye P, Kunimoto M, Khalili-Varasteh M, Chevalier P, Frydman A, Gaillot J, Prenant C, Crouzel M. Interaction of suriclone with central type benzodiazepine receptors in living baboons. European Journal of Pharmacology. 175: 49-55. PMID 1969798 |
0.183 |
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| 2022 |
Mégret L, Mendoza C, Arrieta Lobo M, Brouillet E, Nguyen TT, Bouaziz O, Chambaz A, Néri C. Precision machine learning to understand micro-RNA regulation in neurodegenerative diseases. Frontiers in Molecular Neuroscience. 15: 914830. PMID 36157078 DOI: 10.3389/fnmol.2022.914830 |
0.178 |
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| 2000 |
Ouary S, Bizat N, Altairac S, Ménétrat H, Mittoux V, Condé F, Hantraye P, Brouillet E. Major strain differences in response to chronic systemic administration of the mitochondrial toxin 3-nitropropionic acid in rats: implications for neuroprotection studies. Neuroscience. 97: 521-30. PMID 10828534 DOI: 10.1016/S0306-4522(00)00020-8 |
0.175 |
|
| 1989 |
Brouillet E, Chavoix C, de la Sayette V, Hantraye P, Kunimoto M, Khalili-Varasteh M, Guibert B, Fournier D, Dodd RH, Naquet R. Anticonvulsant activity of the diaryltriazine, LY81067: studies using electroencephalographic recording and positron emission tomography. Neuropharmacology. 28: 351-8. PMID 2501707 DOI: 10.1016/0028-3908(89)90029-4 |
0.164 |
|
| 2001 |
Bertrand E, Brouillet E, Caillé I, Bouillot C, Cole GM, Prochiantz A, Allinquant B. A short cytoplasmic domain of the amyloid precursor protein induces apoptosis in vitro and in vivo. Molecular and Cellular Neurosciences. 18: 503-11. PMID 11922141 DOI: 10.1006/Mcne.2001.1030 |
0.163 |
|
| 2000 |
Brouillet E, Peschanski M, Hantraye P. Toward understanding the molecular pathology of Huntington's disease | Du gene a la maladie: La mort neuronale dans la maladie de Huntington Medecine/Sciences. 16: 57-63. |
0.16 |
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| 1990 |
Brouillet E, Chavoix C, Khalili-Varasteh M, Bottlaender M, Hantraye P, Yorke JC, Maziere M. Quantitative evaluation of benzodiazepine receptors in live Papio papio baboons using positron emission tomography. Molecular Pharmacology. 38: 445-50. PMID 2172764 |
0.156 |
|
| 1987 |
Hantraye P, Brouillet E, Guibert B, Chavoix C, Fukuda H, Prenant C, Crouzel M, Naquet R, Maziere M. Pentylenetetrazol-induced seizure is not mediated by benzodiazepine receptors in vivo. Neuropharmacology. 26: 1509-12. PMID 2825060 DOI: 10.1016/0028-3908(87)90171-7 |
0.152 |
|
| 1988 |
Hantraye P, Brouillet E, Fukuda H, Chavoix C, Guibert B, Dodd RH, Prenant C, Crouzel M, Naquet R, Mazière M. Benzodiazepine receptors studied in living primates by positron emission tomography: antagonist interactions. European Journal of Pharmacology. 153: 25-32. PMID 2905664 DOI: 10.1016/0014-2999(88)90584-5 |
0.138 |
|
| 1996 |
Schmid L, Bottlaender M, Brouillet E, Fuseau C, Mazière M. Vigabatrin modulates benzodiazepine receptor activity in vivo: a positron emission tomography study in baboon. The Journal of Pharmacology and Experimental Therapeutics. 276: 977-83. PMID 8786578 |
0.137 |
|
| 1993 |
Delforge J, Syrota A, Bottlaender M, Varastet M, Loc'h C, Bendriem B, Crouzel C, Brouillet E, Maziere M. Modeling analysis of [11C]flumazenil kinetics studied by PET: application to a critical study of the equilibrium approaches. Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism. 13: 454-68. PMID 8478404 DOI: 10.1038/jcbfm.1993.60 |
0.129 |
|
| 2024 |
Pérot JB, Brouillet E, Flament J. The contribution of preclinical magnetic resonance imaging and spectroscopy to Huntington's disease. Frontiers in Aging Neuroscience. 16: 1306312. PMID 38414634 DOI: 10.3389/fnagi.2024.1306312 |
0.12 |
|
| 2013 |
Aron Badin R, Spinnewyn B, Gaillard M, Jan C, Malgorn C, Van Camp N, Dollé F, Guillermier M, Boulet S, Bertrand A, Savasta M, Auguet M, Brouillet E, Chabrier P, Hantraye P. Correction: IRC-082451, a Novel Multitargeting Molecule, Reduces L-DOPA-Induced Dyskinesias in MPTP Parkinsonian Primates Plos One. 8. DOI: 10.1371/annotation/2efe0ad6-ebf7-434b-94c3-f4225c4d31d7 |
0.114 |
|
| 2007 |
Escartin C, Pierre K, Brouillet E, Delzescaux T, Guillermier M, Dhenain M, Deglon N, Hantraye P, Pellerin L, Bonvento G. CNTF-activated astrocytes display metabolic plasticity and increased resistance to metabolic insults Journal of Cerebral Blood Flow and Metabolism. 27: BP06-01M. |
0.101 |
|
| 1992 |
Chavoix C, Brouillet E, Hantraye P, de la Sayette V, Kunimoto M, Varastet M, Guibert B, Dodd RH, Fournier D, Naquet R. In vivo interactions of pentylenetetrazole with benzodiazepine receptors: lack of direct correlation between benzodiazepine receptor occupancy and convulsant potency of this drug. Epilepsy Research. Supplement. 8: 351-9. PMID 1329823 |
0.096 |
|
| 2022 |
Brouillet E. Extreme conservation of the poly-glutamine tract in huntingtin is related to neurodevelopmental functions: the "better" may become the "enemy of the good" in the course of evolution. Cell Death and Differentiation. PMID 35013554 DOI: 10.1038/s41418-021-00927-4 |
0.09 |
|
| 1995 |
Schmid L, Bottlander M, Brouillet E, Fuseau C, Mazi??re M. Variation of endogenous GABA concentrations modulates benzodiazepine receptor agonist activity in vivo Behavioural Pharmacology. 6: 50. DOI: 10.1097/00008877-199505001-00058 |
0.085 |
|
| 1995 |
Bottlaender M, Schmid L, Fuseau C, Demphel S, Brouillet E, Maziere M. Selective imaging of a GABAA receptor subtype with alpha-5 subunit binding characteristics Behavioural Pharmacology. 6: 103. DOI: 10.1097/00008877-199505001-00122 |
0.081 |
|
| 1999 |
Brouillet E, Trembleau A, Galanaud D, Volovitch M, Bouillot C, Valenza C, Prochiantz A, Allinquant B. The Amyloid Precursor Protein Interacts with GoHeterotrimeric Protein within a Cell Compartment Specialized in Signal Transduction The Journal of Neuroscience. 19: 1717-1727. DOI: 10.1523/JNEUROSCI.19-05-01717.1999 |
0.077 |
|
| 2014 |
Armstrong DR, Brouillet EV, Kennedy AR, Garden JA, Granitzka M, Mulvey RE, Trivett JJ. Donor-activated alkali metal dipyridylamides: co-complexation reactions with zinc alkyls and reactivity studies with benzophenone. Dalton Transactions (Cambridge, England : 2003). 43: 14409-23. PMID 24968199 DOI: 10.1039/C4Dt00914B |
0.063 |
|
| 1987 |
Hantraye P, Brouillet E, Chavoix C, Guibert B, de la Sayette V, Naquet R, Mazière M. [Study of specific binding sites of benzodiazepines using positron emission tomography in live baboons (Papio papio)]. Thã©Rapie. 42: 493-8. PMID 2831635 |
0.043 |
|
| 2000 |
Brouillet E, Peschanski M, Hantraye P. Du gène à la maladie : la mort neuronale dans la maladie de Huntington MéDecine/Sciences. 16: 57. DOI: 10.4267/10608/1502 |
0.022 |
|
| 1991 |
Loc'h C, Hantraye P, Khalili-Varasteh M, Maziere B, Delforge J, Brouillet E, Syrota A, Maziere M. [11C]-Flumazenil metabolites: Measurements of unchanged ligand in plasma using thin layer chromatography and rapid liquid chromatography Journal of Labelled Compounds and Radiopharmaceuticals. 30: 234. |
0.014 |
|
| 2005 |
Thuret G, Brouillet E, Gain P. [Logistical regression of success factors in the former internship examination for medical students]. Presse Mã©Dicale (Paris, France : 1983). 34: 781-5. PMID 16097377 |
0.01 |
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