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Mark E. Dumont - Publications

Affiliations: 
University of Rochester, Rochester, NY 
Area:
General Biophysics, Biochemistry
Website:
https://www.urmc.rochester.edu/people/20969202-mark-e-dumont
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38 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2022 Dumont ME, Konopka JB. Comparison of Experimental Approaches Used to Determine the Structure and Function of the Class D G Protein-Coupled Yeast α-Factor Receptor. Biomolecules. 12. PMID 35740886 DOI: 10.3390/biom12060761  0.497
2021 Connelly SM, Sridharan R, Naider F, Dumont ME. Oligomerization of Yeast α-factor Receptor Detected by Fluorescent Energy Transfer Between Ligands. Biophysical Journal. PMID 34627767 DOI: 10.1016/j.bpj.2021.10.005  0.558
2019 Zhu H, Mathew E, Connelly SM, Zuber J, Sullivan M, Piepenbrink MS, Kobie JJ, Dumont ME. Identification of variant HIV envelope proteins with enhanced affinities for precursors to anti-gp41 broadly neutralizing antibodies. Plos One. 14: e0221550. PMID 31504041 DOI: 10.1371/Journal.Pone.0221550  0.336
2018 Mathew E, Zhu H, Connelly SM, Sullivan MA, Brewer MG, Piepenbrink MS, Kobie JJ, Dewhurst S, Dumont ME. Display of the HIV envelope protein at the yeast cell surface for immunogen development. Plos One. 13: e0205756. PMID 30335821 DOI: 10.1371/Journal.Pone.0205756  0.334
2016 Clark KM, Jenkins JL, Fedoriw N, Dumont ME. Human CaaX Protease ZMPSTE24 Expressed in Yeast: Structure and Inhibition by HIV Protease Inhibitors. Protein Science : a Publication of the Protein Society. PMID 27774687 DOI: 10.1002/Pro.3074  0.318
2016 Sridharan R, Connelly SM, Naider F, Dumont ME. Variable Dependence of Signaling Output on Agonist Occupancy of Ste2p, a G Protein Coupled Receptor in Yeast. The Journal of Biological Chemistry. PMID 27646004 DOI: 10.1074/Jbc.M116.733006  0.661
2015 Mathew E, Dumont ME. A Novel Screening Approach for Optimal and Functional Fusion of T4 Lysozyme in GPCRs. Methods in Enzymology. 557: 27-43. PMID 25950958 DOI: 10.1016/Bs.Mie.2014.12.031  0.663
2015 Zuber J, Danial SA, Connelly SM, Naider F, Dumont ME. Identification of destabilizing and stabilizing mutations of Ste2p, a G protein-coupled receptor in Saccharomyces cerevisiae. Biochemistry. 54: 1787-806. PMID 25647246 DOI: 10.1021/Bi501314T  0.519
2014 Sridharan R, Zuber J, Connelly SM, Mathew E, Dumont ME. Fluorescent approaches for understanding interactions of ligands with G protein coupled receptors. Biochimica Et Biophysica Acta. 1838: 15-33. PMID 24055822 DOI: 10.1016/J.Bbamem.2013.09.005  0.611
2014 Cohen LS, Arshava B, Kauffman S, Mathew E, Fracchiolla KE, Ding FX, Dumont ME, Becker JM, Naider F. Guided reconstitution of membrane protein fragments. Biopolymers. 102: 16-29. PMID 23897574 DOI: 10.1002/Bip.22349  0.478
2013 Pryor EE, Horanyi PS, Clark KM, Fedoriw N, Connelly SM, Koszelak-Rosenblum M, Zhu G, Malkowski MG, Wiener MC, Dumont ME. Structure of the integral membrane protein CAAX protease Ste24p. Science (New York, N.Y.). 339: 1600-4. PMID 23539602 DOI: 10.1126/Science.1232048  0.382
2013 Mathew E, Ding FX, Naider F, Dumont ME. Functional fusions of T4 lysozyme in the third intracellular loop of a G protein-coupled receptor identified by a random screening approach in yeast. Protein Engineering, Design & Selection : Peds. 26: 59-71. PMID 23077276 DOI: 10.1093/Protein/Gzs070  0.634
2012 Gehret AU, Connelly SM, Dumont ME. Functional and physical interactions among Saccharomyces cerevisiae α-factor receptors. Eukaryotic Cell. 11: 1276-88. PMID 22923047 DOI: 10.1128/Ec.00172-12  0.859
2012 Taslimi A, Mathew E, Celić A, Wessel S, Dumont ME. Identifying functionally important conformational changes in proteins: activation of the yeast α-factor receptor Ste2p. Journal of Molecular Biology. 418: 367-78. PMID 22387470 DOI: 10.1016/J.Jmb.2012.02.024  0.824
2011 Mathew E, Bajaj A, Connelly SM, Sargsyan H, Ding FX, Hajduczok AG, Naider F, Dumont ME. Differential interactions of fluorescent agonists and antagonists with the yeast G protein coupled receptor Ste2p. Journal of Molecular Biology. 409: 513-28. PMID 21477594 DOI: 10.1016/J.Jmb.2011.03.059  0.834
2010 Tantry S, Ding FX, Dumont M, Becker JM, Naider F. Binding of fluorinated phenylalanine alpha-factor analogues to Ste2p: evidence for a cation-pi binding interaction between a peptide ligand and its cognate G protein-coupled receptor. Biochemistry. 49: 5007-15. PMID 20420459 DOI: 10.1021/Bi100280F  0.531
2010 Shi S, Notenboom S, Dumont ME, Ballatori N. Identification of human gene products containing Pro-Pro-x-Tyr (PY) motifs that enhance glutathione and endocytotic marker uptake in yeast. Cellular Physiology and Biochemistry : International Journal of Experimental Cellular Physiology, Biochemistry, and Pharmacology. 25: 293-306. PMID 20110690 DOI: 10.1159/000276570  0.37
2010 Clark KM, Fedoriw N, Robinson K, Connelly SM, Randles J, Malkowski MG, DeTitta GT, Dumont ME. Purification of transmembrane proteins from Saccharomyces cerevisiae for X-ray crystallography. Protein Expression and Purification. 71: 207-23. PMID 20045057 DOI: 10.1016/J.Pep.2009.12.012  0.347
2007 Bajaj A, Connelly SM, Gehret AU, Naider F, Dumont ME. Role of extracellular charged amino acids in the yeast alpha-factor receptor. Biochimica Et Biophysica Acta. 1773: 707-17. PMID 17433461 DOI: 10.1016/J.Bbamcr.2007.02.002  0.794
2007 White MA, Clark KM, Grayhack EJ, Dumont ME. Characteristics affecting expression and solubilization of yeast membrane proteins. Journal of Molecular Biology. 365: 621-36. PMID 17078969 DOI: 10.1016/J.Jmb.2006.10.004  0.354
2006 Wang Z, Stalcup LD, Harvey BJ, Weber J, Chloupkova M, Dumont ME, Dean M, Urbatsch IL. Purification and ATP hydrolysis of the putative cholesterol transporters ABCG5 and ABCG8. Biochemistry. 45: 9929-39. PMID 16893193 DOI: 10.1021/Bi0608055  0.342
2006 Gehret AU, Bajaj A, Naider F, Dumont ME. Oligomerization of the yeast alpha-factor receptor: implications for dominant negative effects of mutant receptors. The Journal of Biological Chemistry. 281: 20698-714. PMID 16709573 DOI: 10.1074/Jbc.M513642200  0.81
2005 Gelperin DM, White MA, Wilkinson ML, Kon Y, Kung LA, Wise KJ, Lopez-Hoyo N, Jiang L, Piccirillo S, Yu H, Gerstein M, Dumont ME, Phizicky EM, Snyder M, Grayhack EJ. Biochemical and genetic analysis of the yeast proteome with a movable ORF collection. Genes & Development. 19: 2816-26. PMID 16322557 DOI: 10.1101/Gad.1362105  0.324
2004 Bajaj A, Celić A, Ding FX, Naider F, Becker JM, Dumont ME. A fluorescent alpha-factor analogue exhibits multiple steps on binding to its G protein coupled receptor in yeast. Biochemistry. 43: 13564-78. PMID 15491163 DOI: 10.1021/Bi0494018  0.828
2004 Alexandrov A, Vignali M, LaCount DJ, Quartley E, de Vries C, De Rosa D, Babulski J, Mitchell SF, Schoenfeld LW, Fields S, Hol WG, Dumont ME, Phizicky EM, Grayhack EJ. A facile method for high-throughput co-expression of protein pairs. Molecular & Cellular Proteomics : McP. 3: 934-8. PMID 15240823 DOI: 10.1074/Mcp.T400008-Mcp200  0.322
2004 Roginskaya M, Connelly SM, Kim KS, Patel D, Dumont ME. Effects of mutations in the N terminal region of the yeast G protein alpha-subunit Gpa1p on signaling by pheromone receptors. Molecular Genetics and Genomics : Mgg. 271: 237-48. PMID 14767760 DOI: 10.1007/S00438-004-0975-Y  0.625
2004 Celić A, Connelly SM, Martin NP, Dumont ME. Intensive mutational analysis of G protein-coupled receptors in yeast. Methods in Molecular Biology (Clifton, N.J.). 237: 105-20. PMID 14501043 DOI: 10.1385/1-59259-430-1:105  0.813
2003 Arevalo E, Estephan R, Madeo J, Arshava B, Dumont M, Becker JM, Naider F. Biosynthesis and biophysical analysis of domains of a yeast G protein-coupled receptor. Biopolymers. 71: 516-31. PMID 14517901 DOI: 10.1002/Bip.10491  0.543
2003 Celić A, Martin NP, Son CD, Becker JM, Naider F, Dumont ME. Sequences in the intracellular loops of the yeast pheromone receptor Ste2p required for G protein activation. Biochemistry. 42: 3004-17. PMID 12627966 DOI: 10.1021/Bi0269308  0.831
2002 Martin NP, Celić A, Dumont ME. Mutagenic mapping of helical structures in the transmembrane segments of the yeast alpha-factor receptor. Journal of Molecular Biology. 317: 765-88. PMID 11955023 DOI: 10.1006/Jmbi.2002.5444  0.798
2001 Erlenbach I, Kostenis E, Schmidt C, Serradeil-Le Gal C, Raufaste D, Dumont ME, Pausch MH, Wess J. Single amino acid substitutions and deletions that alter the G protein coupling properties of the V2 vasopressin receptor identified in yeast by receptor random mutagenesis. The Journal of Biological Chemistry. 276: 29382-92. PMID 11375990 DOI: 10.1074/Jbc.M103203200  0.705
2000 Sommers CM, Martin NP, Akal-Strader A, Becker JM, Naider F, Dumont ME. A limited spectrum of mutations causes constitutive activation of the yeast alpha-factor receptor. Biochemistry. 39: 6898-909. PMID 10841771 DOI: 10.1021/Bi992616A  0.831
1999 Leavitt LM, Macaluso CR, Kim KS, Martin NP, Dumont ME. Dominant negative mutations in the alpha-factor receptor, a G protein-coupled receptor encoded by the STE2 gene of the yeast Saccharomyces cerevisiae. Molecular & General Genetics : Mgg. 261: 917-32. PMID 10485282 DOI: 10.1007/S004380051039  0.784
1999 Martin NP, Leavitt LM, Sommers CM, Dumont ME. Assembly of G protein-coupled receptors from fragments: identification of functional receptors with discontinuities in each of the loops connecting transmembrane segments. Biochemistry. 38: 682-95. PMID 9888809 DOI: 10.1021/Bi982062W  0.785
1997 Sommers CM, Dumont ME. Genetic interactions among the transmembrane segments of the G protein coupled receptor encoded by the yeast STE2 gene. Journal of Molecular Biology. 266: 559-75. PMID 9067610 DOI: 10.1006/Jmbi.1996.0816  0.678
1990 Dumont ME, Sherman F, Thomas DY. Protein targeting and protein secretion. Genome. 31: 1109-10. PMID 2632343 DOI: 10.1139/G89-199  0.364
1987 Dumont M, Ernst J, Hampsey D, Sherman F. Identification and sequence of the gene encoding cytochrome c heme lyase in the yeast Saccharomyces cerevisiae. The Embo Journal. 6: 235-241. DOI: 10.1002/J.1460-2075.1987.Tb04744.X  0.323
1985 Dumont ME, Trewhella J, Engelman DM, Richards FM. Stability of transmembrane regions in bacteriorhodopsin studied by progressive proteolysis. The Journal of Membrane Biology. 88: 233-47. PMID 3913776 DOI: 10.1007/Bf01871088  0.317
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