Year |
Citation |
Score |
2020 |
Choi S, Singh I, Singh AK, Khan M, Won J. Asymmetric dimethylarginine exacerbates cognitive dysfunction associated with cerebrovascular pathology. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. PMID 32239698 DOI: 10.1096/Fj.201901318R |
0.333 |
|
2019 |
Islam SMT, Won J, Khan M, Chavin KD, Singh I. Peroxisomal footprint in the pathogenesis of nonalcoholic steatohepatitis. Annals of Hepatology. PMID 31870746 DOI: 10.1016/J.Aohep.2019.11.007 |
0.322 |
|
2019 |
Khan M, Dhammu TS, Qiao F, Kumar P, Singh AK, Singh I. S-Nitrosoglutathione Mimics the Beneficial Activity of Endothelial Nitric Oxide Synthase-Derived Nitric Oxide in a Mouse Model of Stroke. Journal of Stroke and Cerebrovascular Diseases : the Official Journal of National Stroke Association. 104470. PMID 31680031 DOI: 10.1016/J.Jstrokecerebrovasdis.2019.104470 |
0.342 |
|
2019 |
Khan M, Singh I. Therapeutic exploitation of the S-nitrosoglutathione/S-nitrosylation mechanism for the treatment of contusion spinal cord injury. Neural Regeneration Research. 14: 973-974. PMID 30762004 DOI: 10.4103/1673-5374.250572 |
0.301 |
|
2018 |
Choi S, Saxena N, Dhammu T, Khan M, Singh AK, Singh I, Won J. Regulation of endothelial barrier integrity by redox-dependent nitric oxide signaling: Implication in traumatic and inflammatory brain injuries. Nitric Oxide : Biology and Chemistry. PMID 30590116 DOI: 10.1016/J.Niox.2018.12.007 |
0.388 |
|
2018 |
Khan M, Dhammu TS, Singh I, Singh AK. Amelioration of spinal cord injury in rats by blocking peroxynitrite/calpain activity. Bmc Neuroscience. 19: 50. PMID 30103682 DOI: 10.1186/S12868-018-0450-Z |
0.36 |
|
2018 |
Khan M, Shunmugavel A, Dhammu TS, Khan H, Singh I, Singh AK. Combined treatment with GSNO and CAPE accelerates functional recovery via additive antioxidant activities in a mouse model of TBI. Journal of Neuroscience Research. PMID 30027580 DOI: 10.1002/Jnr.24279 |
0.372 |
|
2018 |
Singh I, Nath N, Saxena N, Singh AK, Won JS. Regulation of IL-10 and IL-17 mediated experimental autoimmune encephalomyelitis by S-nitrosoglutathione. Immunobiology. PMID 29960806 DOI: 10.1016/J.Imbio.2018.06.003 |
0.328 |
|
2018 |
Saxena N, Won J, Choi S, Singh AK, Singh I. S-Nitrosoglutathione reductase (GSNOR) inhibitor as an immune modulator in experimental autoimmune encephalomyelitis. Free Radical Biology & Medicine. PMID 29694854 DOI: 10.1016/J.Freeradbiomed.2018.04.558 |
0.353 |
|
2018 |
Dasgupta S, Gomez JJ, Singh I, Khan M. S-Nitrosylation in regulation of inflammation and cell damage. Current Drug Targets. PMID 29437005 DOI: 10.2174/1389450119666180213094747 |
0.342 |
|
2018 |
Singh I, Samuvel DJ, Choi S, Saxena N, Singh AK, Won J. Combination therapy of lovastatin and AMPK activator improves mitochondrial and peroxisomal functions and clinical disease in EAE model. Immunology. PMID 29331024 DOI: 10.1111/Imm.12893 |
0.345 |
|
2017 |
Khan M, Khan H, Singh I, Singh AK. Hypoxia inducible factor-1 alpha stabilization for regenerative therapy in traumatic brain injury. Neural Regeneration Research. 12: 696-701. PMID 28616019 DOI: 10.4103/1673-5374.206632 |
0.322 |
|
2017 |
Kim J, Choi S, Saxena N, Singh AK, Singh I, Won JS. Regulation of STAT3 and NF-κB Activations by S-Nitrosylation in Multiple Myeloma. Free Radical Biology & Medicine. PMID 28232202 DOI: 10.1016/J.Freeradbiomed.2017.02.039 |
0.34 |
|
2016 |
Khan M, Dhammu TS, Baarine M, Kim J, Paintlia MK, Singh I, Singh AK. GSNO promotes functional recovery in experimental TBI by stabilizing HIF-1α. Behavioural Brain Research. PMID 27780722 DOI: 10.1016/J.Bbr.2016.10.037 |
0.313 |
|
2016 |
Won JS, Singh AK, Singh I. Biochemical, cell biological, pathological, and therapeutic aspects of Krabbe's disease. Journal of Neuroscience Research. 94: 990-1006. PMID 27638584 DOI: 10.1002/Jnr.23873 |
0.364 |
|
2016 |
Samuvel DJ, Shunmugavel A, Singh AK, Singh I, Khan M. S-Nitrosoglutathione ameliorates acute renal dysfunction in a rat model of lipopolysaccharide-induced sepsis. The Journal of Pharmacy and Pharmacology. PMID 27484743 DOI: 10.1111/Jphp.12608 |
0.3 |
|
2016 |
Nie X, Lowe DW, Rollins LG, Bentzley J, Fraser JL, Martin R, Singh I, Jenkins D. Sex-specific effects of N-acetylcysteine in neonatal rats treated with hypothermia after severe hypoxia-ischemia. Neuroscience Research. PMID 26851769 DOI: 10.1016/J.Neures.2016.01.008 |
0.32 |
|
2015 |
Singh I, Kim J, Singh AK, Sharma AK, Won JS. STAT3 Regulation By S-Nitrosylation: Implication In Cancer. Redox Biology. 5: 416-417. PMID 28162277 DOI: 10.1016/J.Redox.2015.09.021 |
0.392 |
|
2015 |
Singh I, Prasad R, Agarwal V, Tripathi RL. Does Rigid Cystoscopy Affect the Total Serum Prostate-Specific Antigen Levels? The Indian Journal of Surgery. 77: 365-9. PMID 26730027 DOI: 10.1007/s12262-013-0844-1 |
0.65 |
|
2015 |
Khan M, Dhammu TS, Matsuda F, Annamalai B, Dhindsa TS, Singh I, Singh AK. Targeting the nNOS/peroxynitrite/calpain system to confer neuroprotection and aid functional recovery in a mouse model of TBI. Brain Research. PMID 26596859 DOI: 10.1016/J.Brainres.2015.11.015 |
0.388 |
|
2015 |
Baarine M, Khan M, Singh A, Singh I. Functional Characterization of IPSC-Derived Brain Cells as a Model for X-Linked Adrenoleukodystrophy. Plos One. 10: e0143238. PMID 26581106 DOI: 10.1371/Journal.Pone.0143238 |
0.373 |
|
2015 |
Samuvel DJ, Saxena N, Dhindsa JS, Singh AK, Gill GS, Grobelny DW, Singh I. AKP-11 - A Novel S1P1 Agonist with Favorable Safety Profile Attenuates Experimental Autoimmune Encephalomyelitis in Rat Model of Multiple Sclerosis. Plos One. 10: e0141781. PMID 26513477 DOI: 10.1371/Journal.Pone.0141781 |
0.326 |
|
2015 |
Won JS, Annamalai B, Choi S, Singh I, Singh AK. S-nitrosoglutathione reduces tau hyper-phosphorylation and provides neuroprotection in rat model of chronic cerebral hypoperfusion. Brain Research. PMID 26271717 DOI: 10.1016/J.Brainres.2015.07.057 |
0.395 |
|
2015 |
Kaliyaperumal K, Sharma AK, McDonald DG, Dhindsa JS, Yount C, Singh AK, Won JS, Singh I. S-nitrosoglutathione-mediated STAT3 regulation in efficacy of radiotherapy and cisplatin therapy in head and neck squamous cell carcinoma. Redox Biology. 6: 41-50. PMID 26177470 DOI: 10.1016/J.Redox.2015.07.001 |
0.367 |
|
2015 |
Khan M, Dhammu TS, Matsuda F, Singh AK, Singh I. Blocking a vicious cycle nNOS/peroxynitrite/AMPK by S-nitrosoglutathione: implication for stroke therapy. Bmc Neuroscience. 16: 42. PMID 26174015 DOI: 10.1186/S12868-015-0179-X |
0.343 |
|
2015 |
Khan M, Shunmugavel A, Dhammu TS, Matsuda F, Singh AK, Singh I. Oral administration of cytosolic PLA2 inhibitor arachidonyl trifluoromethyl ketone ameliorates cauda equina compression injury in rats. Journal of Neuroinflammation. 12: 94. PMID 25971887 DOI: 10.1186/S12974-015-0311-Y |
0.364 |
|
2015 |
Khan M, Dhammu TS, Matsuda F, Baarine M, Dhindsa TS, Singh I, Singh AK. Promoting endothelial function by S-nitrosoglutathione through the HIF-1α/VEGF pathway stimulates neurorepair and functional recovery following experimental stroke in rats. Drug Design, Development and Therapy. 9: 2233-47. PMID 25945035 DOI: 10.2147/Dddt.S77115 |
0.344 |
|
2015 |
Baarine M, Beeson C, Singh A, Singh I. ABCD1 deletion-induced mitochondrial dysfunction is corrected by SAHA: implication for adrenoleukodystrophy. Journal of Neurochemistry. 133: 380-96. PMID 25393703 DOI: 10.1111/Jnc.12992 |
0.306 |
|
2015 |
Shunmugavel A, Khan M, Hughes FM, Purves JT, Singh A, Singh I. S-Nitrosoglutathione protects the spinal bladder: novel therapeutic approach to post-spinal cord injury bladder remodeling. Neurourology and Urodynamics. 34: 519-26. PMID 24853799 DOI: 10.1002/Nau.22619 |
0.33 |
|
2014 |
Kim J, Won JS, Singh AK, Sharma AK, Singh I. STAT3 regulation by S-nitrosylation: implication for inflammatory disease. Antioxidants & Redox Signaling. 20: 2514-27. PMID 24063605 DOI: 10.1089/Ars.2013.5223 |
0.325 |
|
2013 |
Paintlia AS, Mohan S, Singh I. Combinatorial Effect of Metformin and Lovastatin Impedes T-cell Autoimmunity and Neurodegeneration in Experimental Autoimmune Encephalomyelitis. Journal of Clinical & Cellular Immunology. 4. PMID 24324917 DOI: 10.4172/2155-9899.1000149 |
0.354 |
|
2013 |
Singh J, Khan M, Pujol A, Baarine M, Singh I. Histone deacetylase inhibitor upregulates peroxisomal fatty acid oxidation and inhibits apoptotic cell death in abcd1-deficient glial cells. Plos One. 8: e70712. PMID 23923017 DOI: 10.1371/Journal.Pone.0070712 |
0.391 |
|
2013 |
Paintlia AS, Paintlia MK, Singh AK, Singh I. Modulation of Rho-Rock signaling pathway protects oligodendrocytes against cytokine toxicity via PPAR-α-dependent mechanism. Glia. 61: 1500-17. PMID 23839981 DOI: 10.1002/Glia.22537 |
0.357 |
|
2013 |
Singh I, Prasad R. Primary urachal mucinous adenocarcinoma of the urinary bladder. Journal of Clinical and Diagnostic Research : Jcdr. 7: 911-3. PMID 23814741 DOI: 10.7860/JCDR/2013/5597.2973 |
0.643 |
|
2013 |
Paintlia AS, Paintlia MK, Mohan S, Singh AK, Singh I. AMP-activated protein kinase signaling protects oligodendrocytes that restore central nervous system functions in an experimental autoimmune encephalomyelitis model. The American Journal of Pathology. 183: 526-41. PMID 23759513 DOI: 10.1016/J.Ajpath.2013.04.030 |
0.42 |
|
2013 |
Won JS, Kim J, Paintlia MK, Singh I, Singh AK. Role of endogenous psychosine accumulation in oligodendrocyte differentiation and survival: implication for Krabbe disease. Brain Research. 1508: 44-52. PMID 23438514 DOI: 10.1016/J.Brainres.2013.02.024 |
0.372 |
|
2013 |
Singh J, Khan M, Singh I. Caffeic acid phenethyl ester induces adrenoleukodystrophy (Abcd2) gene in human X-ALD fibroblasts and inhibits the proinflammatory response in Abcd1/2 silenced mouse primary astrocytes. Biochimica Et Biophysica Acta. 1831: 747-58. PMID 23318275 DOI: 10.1016/J.Bbalip.2013.01.004 |
0.415 |
|
2013 |
Paintlia MK, Paintlia AS, Singh AK, Singh I. S-nitrosoglutathione induces ciliary neurotrophic factor expression in astrocytes, which has implications to protect the central nervous system under pathological conditions. The Journal of Biological Chemistry. 288: 3831-43. PMID 23264628 DOI: 10.1074/Jbc.M112.405654 |
0.395 |
|
2013 |
Won JS, Kim J, Annamalai B, Shunmugavel A, Singh I, Singh AK. Protective role of S-nitrosoglutathione (GSNO) against cognitive impairment in rat model of chronic cerebral hypoperfusion. Journal of Alzheimer's Disease : Jad. 34: 621-35. PMID 23254638 DOI: 10.3233/Jad-121786 |
0.389 |
|
2013 |
Shunmugavel A, Martin MM, Khan M, Copay AG, Subach BR, Schuler TC, Singh I. Simvastatin ameliorates cauda equina compression injury in a rat model of lumbar spinal stenosis. Journal of Neuroimmune Pharmacology : the Official Journal of the Society On Neuroimmune Pharmacology. 8: 274-86. PMID 23188522 DOI: 10.1007/S11481-012-9419-3 |
0.364 |
|
2012 |
Shunmugavel A, Khan M, Martin MM, Copay AG, Subach BR, Schuler TC, Singh I. S-Nitrosoglutathione administration ameliorates cauda equina compression injury in rats. Neuroscience and Medicine. 3: 294-305. PMID 23997981 DOI: 10.4236/Nm.2012.33034 |
0.37 |
|
2012 |
Khan M, Dhammu TS, Sakakima H, Shunmugavel A, Gilg AG, Singh AK, Singh I. The inhibitory effect of S-nitrosoglutathione on blood-brain barrier disruption and peroxynitrite formation in a rat model of experimental stroke. Journal of Neurochemistry. 123: 86-97. PMID 23050646 DOI: 10.1111/J.1471-4159.2012.07947.X |
0.77 |
|
2012 |
Chang EY, Zhang J, Sullivan S, Newman R, Singh I. N-acetylcysteine prevents preterm birth by attenuating the LPS-induced expression of contractile associated proteins in an animal model. The Journal of Maternal-Fetal & Neonatal Medicine : the Official Journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians. 25: 2395-400. PMID 22676250 DOI: 10.3109/14767058.2012.697942 |
0.324 |
|
2012 |
Shunmugavel A, Khan M, Chou PC, Singh I. Spinal cord injury induced arrest in estrous cycle of rats is ameliorated by S-nitrosoglutathione: novel therapeutic agent to treat amenorrhea. The Journal of Sexual Medicine. 9: 148-58. PMID 22024253 DOI: 10.1111/J.1743-6109.2011.02526.X |
0.321 |
|
2012 |
Martin M, Subach BR, Shunmugavel A, Copay AG, Schuler TC, Singh I, Khan M. S-Nitrosoglutathione Protects Against Secondary Inflammatory Effects of Acute Spinal Cord Injury in Rats The Spine Journal. 12. DOI: 10.1016/J.Spinee.2012.08.246 |
0.344 |
|
2011 |
Singh J, Khan M, Singh I. HDAC inhibitor SAHA normalizes the levels of VLCFAs in human skin fibroblasts from X-ALD patients and downregulates the expression of proinflammatory cytokines in Abcd1/2-silenced mouse astrocytes. Journal of Lipid Research. 52: 2056-69. PMID 21891797 DOI: 10.1194/Jlr.M017491 |
0.405 |
|
2011 |
Khan M, Sakakima H, Dhammu TS, Shunmugavel A, Im YB, Gilg AG, Singh AK, Singh I. S-nitrosoglutathione reduces oxidative injury and promotes mechanisms of neurorepair following traumatic brain injury in rats. Journal of Neuroinflammation. 8: 78. PMID 21733162 DOI: 10.1186/1742-2094-8-78 |
0.766 |
|
2011 |
Chang EY, Zhang J, Sullivan S, Newman R, Singh I. N-acetylcysteine attenuates the maternal and fetal proinflammatory response to intrauterine LPS injection in an animal model for preterm birth and brain injury. The Journal of Maternal-Fetal & Neonatal Medicine : the Official Journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians. 24: 732-40. PMID 21219105 DOI: 10.3109/14767058.2010.528089 |
0.366 |
|
2011 |
Paintlia MK, Paintlia AS, Singh AK, Singh I. Synergistic activity of interleukin-17 and tumor necrosis factor-α enhances oxidative stress-mediated oligodendrocyte apoptosis. Journal of Neurochemistry. 116: 508-21. PMID 21143599 DOI: 10.1111/J.1471-4159.2010.07136.X |
0.383 |
|
2010 |
Tatar CL, Appikatla S, Bessert DA, Paintlia AS, Singh I, Skoff RP. Increased Plp1 gene expression leads to massive microglial cell activation and inflammation throughout the brain. Asn Neuro. 2: e00043. PMID 20885931 DOI: 10.1042/An20100016 |
0.361 |
|
2010 |
Paintlia AS, Paintlia MK, Singh AK, Orak JK, Singh I. Activation of PPAR-γ and PTEN cascade participates in lovastatin-mediated accelerated differentiation of oligodendrocyte progenitor cells. Glia. 58: 1669-85. PMID 20578043 DOI: 10.1002/Glia.21039 |
0.385 |
|
2010 |
Contreras MA, Ries WL, Shanmugarajan S, Arboleda G, Singh I, Singh AK. Factors that affect postnatal bone growth retardation in the twitcher murine model of Krabbe disease. Biochimica Et Biophysica Acta. 1802: 601-8. PMID 20441793 DOI: 10.1016/J.Bbadis.2010.04.006 |
0.311 |
|
2010 |
Vluggens A, Andreoletti P, Viswakarma N, Jia Y, Matsumoto K, Kulik W, Khan M, Huang J, Guo D, Yu S, Sarkar J, Singh I, Rao MS, Wanders RJ, Reddy JK, et al. Reversal of mouse Acyl-CoA oxidase 1 (ACOX1) null phenotype by human ACOX1b isoform [corrected]. Laboratory Investigation; a Journal of Technical Methods and Pathology. 90: 696-708. PMID 20195242 DOI: 10.1038/Labinvest.2010.46 |
0.337 |
|
2010 |
Khan M, Singh J, Gilg AG, Uto T, Singh I. Very long-chain fatty acid accumulation causes lipotoxic response via 5-lipoxygenase in cerebral adrenoleukodystrophy. Journal of Lipid Research. 51: 1685-95. PMID 20173212 DOI: 10.1194/Jlr.M002329 |
0.777 |
|
2010 |
Nath N, Morinaga O, Singh I. S-nitrosoglutathione a physiologic nitric oxide carrier attenuates experimental autoimmune encephalomyelitis. Journal of Neuroimmune Pharmacology : the Official Journal of the Society On Neuroimmune Pharmacology. 5: 240-51. PMID 20091246 DOI: 10.1007/S11481-009-9187-X |
0.371 |
|
2009 |
Khan M, Im YB, Shunmugavel A, Gilg AG, Dhindsa RK, Singh AK, Singh I. Administration of S-nitrosoglutathione after traumatic brain injury protects the neurovascular unit and reduces secondary injury in a rat model of controlled cortical impact. Journal of Neuroinflammation. 6: 32. PMID 19889224 DOI: 10.1186/1742-2094-6-32 |
0.756 |
|
2009 |
Hoda MN, Singh I, Singh AK, Khan M. Reduction of lipoxidative load by secretory phospholipase A2 inhibition protects against neurovascular injury following experimental stroke in rat. Journal of Neuroinflammation. 6: 21. PMID 19678934 DOI: 10.1186/1742-2094-6-21 |
0.336 |
|
2009 |
Singh I, Singh AK, Contreras MA. Peroxisomal dysfunction in inflammatory childhood white matter disorders: an unexpected contributor to neuropathology. Journal of Child Neurology. 24: 1147-57. PMID 19605772 DOI: 10.1177/0883073809338327 |
0.334 |
|
2009 |
Nath N, Khan M, Paintlia MK, Singh I, Hoda MN, Giri S. Metformin attenuated the autoimmune disease of the central nervous system in animal models of multiple sclerosis. Journal of Immunology (Baltimore, Md. : 1950). 182: 8005-14. PMID 19494326 DOI: 10.4049/jimmunol.0803563 |
0.345 |
|
2009 |
Nath N, Khan M, Rattan R, Mangalam A, Makkar RS, de Meester C, Bertrand L, Singh I, Chen Y, Viollet B, Giri S. Loss of AMPK exacerbates experimental autoimmune encephalomyelitis disease severity. Biochemical and Biophysical Research Communications. 386: 16-20. PMID 19486896 DOI: 10.1016/J.Bbrc.2009.05.106 |
0.65 |
|
2009 |
Singh J, Khan M, Singh I. Silencing of Abcd1 and Abcd2 genes sensitizes astrocytes for inflammation: implication for X-adrenoleukodystrophy. Journal of Lipid Research. 50: 135-47. PMID 18723473 DOI: 10.1194/Jlr.M800321-Jlr200 |
0.408 |
|
2009 |
Paintlia AS, Paintlia MK, Singh I, Skoff RB, Singh AK. Combination therapy of lovastatin and rolipram provides neuroprotection and promotes neurorepair in inflammatory demyelination model of multiple sclerosis. Glia. 57: 182-93. PMID 18720408 DOI: 10.1002/Glia.20745 |
0.343 |
|
2008 |
Markovic-Plese S, Singh AK, Singh I. Therapeutic potential of statins in multiple sclerosis: immune modulation, neuroprotection and neurorepair. Future Neurology. 3: 153. PMID 20107624 DOI: 10.2217/14796708.3.2.153 |
0.357 |
|
2008 |
Uto T, Contreras MA, Gilg AG, Singh I. Oxidative imbalance in nonstimulated X-adrenoleukodystrophy-derived lymphoblasts. Developmental Neuroscience. 30: 410-8. PMID 19127062 DOI: 10.1159/000191212 |
0.769 |
|
2008 |
Paintlia AS, Paintlia MK, Singh I, Singh AK. Combined medication of lovastatin with rolipram suppresses severity of experimental autoimmune encephalomyelitis. Experimental Neurology. 214: 168-80. PMID 18775426 DOI: 10.1016/J.Expneurol.2008.07.024 |
0.339 |
|
2008 |
Prasad R, Giri S, Singh AK, Singh I. 15-deoxy-delta12,14-prostaglandin J2 attenuates endothelial-monocyte interaction: implication for inflammatory diseases. Journal of Inflammation (London, England). 5: 14. PMID 18691416 DOI: 10.1186/1476-9255-5-14 |
0.74 |
|
2008 |
Contreras MA, Haq E, Uto T, Singh I, Singh AK. Psychosine-induced alterations in peroxisomes of twitcher mouse liver. Archives of Biochemistry and Biophysics. 477: 211-8. PMID 18602885 DOI: 10.1016/J.Abb.2008.06.012 |
0.359 |
|
2008 |
Lee JK, Won JS, Singh AK, Singh I. Statin inhibits kainic acid-induced seizure and associated inflammation and hippocampal cell death. Neuroscience Letters. 440: 260-4. PMID 18583044 DOI: 10.1016/J.Neulet.2008.05.112 |
0.311 |
|
2008 |
Paintlia MK, Paintlia AS, Singh AK, Singh I. Attenuation of lipopolysaccharide-induced inflammatory response and phospholipids metabolism at the feto-maternal interface by N-acetyl cysteine. Pediatric Research. 64: 334-9. PMID 18552708 DOI: 10.1203/Pdr.0B013E318181E07C |
0.351 |
|
2008 |
Khan M, Singh J, Singh I. Plasmalogen deficiency in cerebral adrenoleukodystrophy and its modulation by lovastatin. Journal of Neurochemistry. 106: 1766-79. PMID 18540993 DOI: 10.1111/J.1471-4159.2008.05513.X |
0.381 |
|
2008 |
Paintlia MK, Paintlia AS, Contreras MA, Singh I, Singh AK. Lipopolysaccharide-induced peroxisomal dysfunction exacerbates cerebral white matter injury: attenuation by N-acetyl cysteine. Experimental Neurology. 210: 560-76. PMID 18291369 DOI: 10.1016/J.Expneurol.2007.12.011 |
0.39 |
|
2008 |
Giri S, Khan M, Nath N, Singh I, Singh AK. The role of AMPK in psychosine mediated effects on oligodendrocytes and astrocytes: implication for Krabbe disease. Journal of Neurochemistry. 105: 1820-33. PMID 18248608 DOI: 10.1111/J.1471-4159.2008.05279.X |
0.439 |
|
2008 |
Paintlia AS, Paintlia MK, Singh AK, Singh I. Inhibition of rho family functions by lovastatin promotes myelin repair in ameliorating experimental autoimmune encephalomyelitis. Molecular Pharmacology. 73: 1381-93. PMID 18239032 DOI: 10.1124/Mol.107.044230 |
0.373 |
|
2008 |
Paintlia MK, Paintlia AS, Khan M, Singh I, Singh AK. Modulation of peroxisome proliferator-activated receptor-alpha activity by N-acetyl cysteine attenuates inhibition of oligodendrocyte development in lipopolysaccharide stimulated mixed glial cultures. Journal of Neurochemistry. 105: 956-70. PMID 18205750 DOI: 10.1111/J.1471-4159.2007.05199.X |
0.397 |
|
2008 |
Class QA, Buss C, Davis EP, Gierczak M, Pattillo C, Chicz-DeMet A, Sandman CA, Uto T, Contreras MA, Gilg AG, Singh I, Yin S, Wang J, Bianco-Batlles MD, Sosunov A, et al. Contents Vol. 30, 2008 Developmental Neuroscience. 30. DOI: 10.1159/000196972 |
0.708 |
|
2008 |
Class QA, Buss C, Davis EP, Gierczak M, Pattillo C, Chicz-DeMet A, Sandman CA, Uto T, Contreras MA, Gilg AG, Singh I, Yin S, Wang J, Bianco-Batlles MD, Sosunov A, et al. Subject Index Vol. 30, 2008 Developmental Neuroscience. 30: 428-428. DOI: 10.1159/000196971 |
0.701 |
|
2008 |
Khan M, Giri S, Singh I, Singh AK. Inhibition of peroxisomal functions and production of excessive oxidative stress by psychosine in rat C6 glial cells Journal of Neurochemistry. 81: 108-111. DOI: 10.1046/J.1471-4159.81.S1.42_11.X |
0.401 |
|
2008 |
Khan M, Sekhon BK, Sekhon CS, Singh I, Singh AK. Sphingolipids in rat model of transient focal cerebral ischemia: implication for stroke injury Journal of Neurochemistry. 81: 108-111. DOI: 10.1046/J.1471-4159.81.S1.42_10.X |
0.359 |
|
2008 |
Sekhon BK, Sekhon CS, Khan M, Barbosa E, Patel SJ, Singh I, Singh AK. N‐acetyl cysteine protects against injury in animal model of transient focal cerebral ischemia Journal of Neurochemistry. 81: 101-105. DOI: 10.1046/J.1471-4159.81.S1.40_12.X |
0.355 |
|
2008 |
Rattan R, Giri S, Singh I. Lovastatin induced cytokine-mediated inducible nitric oxide synthase (INOS) expression in brain transformed cell lines Journal of Neurochemistry. 81: 54-56. DOI: 10.1046/J.1471-4159.81.S1.18_8.X |
0.686 |
|
2008 |
Paintlia AS, Singh AK, Singh I. The role of inflammatory mediators in the pathophysiology of X-ALD disease Journal of Neurochemistry. 81: 49-51. DOI: 10.1046/J.1471-4159.81.S1.16_8.X |
0.373 |
|
2007 |
Won JS, Singh AK, Singh I. Lactosylceramide: a lipid second messenger in neuroinflammatory disease. Journal of Neurochemistry. 103: 180-91. PMID 17986153 DOI: 10.1111/J.1471-4159.2007.04822.X |
0.399 |
|
2007 |
Sengupta TK, Leclerc GM, Hsieh-Kinser TT, Leclerc GJ, Singh I, Barredo JC. Cytotoxic effect of 5-aminoimidazole-4-carboxamide-1-beta-4-ribofuranoside (AICAR) on childhood acute lymphoblastic leukemia (ALL) cells: implication for targeted therapy. Molecular Cancer. 6: 46. PMID 17623090 DOI: 10.1186/1476-4598-6-46 |
0.35 |
|
2007 |
Haq E, Rohrer B, Nath N, Crosson CE, Singh I. S-nitrosoglutathione prevents interphotoreceptor retinoid-binding protein (IRBP(161-180))-induced experimental autoimmune uveitis. Journal of Ocular Pharmacology and Therapeutics : the Official Journal of the Association For Ocular Pharmacology and Therapeutics. 23: 221-31. PMID 17593005 DOI: 10.1089/Jop.2007.0023 |
0.413 |
|
2007 |
Khan M, Elango C, Ansari MA, Singh I, Singh AK. Caffeic acid phenethyl ester reduces neurovascular inflammation and protects rat brain following transient focal cerebral ischemia. Journal of Neurochemistry. 102: 365-77. PMID 17437550 DOI: 10.1111/J.1471-4159.2007.04526.X |
0.44 |
|
2007 |
Pannu R, Christie DK, Barbosa E, Singh I, Singh AK. Post-trauma Lipitor treatment prevents endothelial dysfunction, facilitates neuroprotection, and promotes locomotor recovery following spinal cord injury. Journal of Neurochemistry. 101: 182-200. PMID 17217414 DOI: 10.1111/J.1471-4159.2006.04354.X |
0.801 |
|
2007 |
Prasad R, Giri S, Nath N, Singh I, Singh AK. GSNO attenuates EAE disease by S-nitrosylation-mediated modulation of endothelial-monocyte interactions. Glia. 55: 65-77. PMID 17019693 DOI: 10.1002/Glia.20436 |
0.753 |
|
2007 |
Pannu R, Singh AK, Singh I. Tumor Necrosis Factor‐[Alpha] regulates lactosylceramide synthesis via activation of Protein Kinase C: A novel function of Gi‐linked sphingosine‐1‐phosphate receptor The Faseb Journal. 21. DOI: 10.1096/Fasebj.21.5.A604-B |
0.767 |
|
2007 |
Qiao F, Atkinson C, Song H, Pannu R, Singh I, Tomlinson S. The role of complement in spinal cord injury Molecular Immunology. 44: 231. DOI: 10.1016/J.Molimm.2006.07.196 |
0.768 |
|
2006 |
Qiao F, Atkinson C, Song H, Pannu R, Singh I, Tomlinson S. Complement plays an important role in spinal cord injury and represents a therapeutic target for improving recovery following trauma. The American Journal of Pathology. 169: 1039-47. PMID 16936276 DOI: 10.2353/Ajpath.2006.060248 |
0.783 |
|
2006 |
Paintlia AS, Paintlia MK, Singh I, Singh AK. Immunomodulatory effect of combination therapy with lovastatin and 5-aminoimidazole-4-carboxamide-1-beta-D-ribofuranoside alleviates neurodegeneration in experimental autoimmune encephalomyelitis. The American Journal of Pathology. 169: 1012-25. PMID 16936274 DOI: 10.2353/Ajpath.2006.051309 |
0.326 |
|
2006 |
Giri S, Rattan R, Haq E, Khan M, Yasmin R, Won JS, Key L, Singh AK, Singh I. AICAR inhibits adipocyte differentiation in 3T3L1 and restores metabolic alterations in diet-induced obesity mice model. Nutrition & Metabolism. 3: 31. PMID 16901342 DOI: 10.1186/1743-7075-3-31 |
0.606 |
|
2006 |
Peng X, Jin J, Giri S, Montes M, Sujkowski D, Tang Y, Smrtka J, Vollmer T, Singh I, Markovic-Plese S. Immunomodulatory effects of 3-hydroxy-3-methylglutaryl coenzyme-A reductase inhibitors, potential therapy for relapsing remitting multiple sclerosis. Journal of Neuroimmunology. 178: 130-9. PMID 16870268 DOI: 10.1016/J.Jneuroim.2006.06.005 |
0.37 |
|
2006 |
Nath N, Prasad R, Giri S, Singh AK, Singh I. T-bet is essential for the progression of experimental autoimmune encephalomyelitis. Immunology. 118: 384-91. PMID 16827899 DOI: 10.1111/J.1365-2567.2006.02385.X |
0.713 |
|
2006 |
Prasad R, Giri S, Nath N, Singh I, Singh AK. 5-aminoimidazole-4-carboxamide-1-beta-4-ribofuranoside attenuates experimental autoimmune encephalomyelitis via modulation of endothelial-monocyte interaction. Journal of Neuroscience Research. 84: 614-25. PMID 16770773 DOI: 10.1002/Jnr.20953 |
0.764 |
|
2006 |
Pannu R, Singh I. Pharmacological strategies for the regulation of inducible nitric oxide synthase: neurodegenerative versus neuroprotective mechanisms. Neurochemistry International. 49: 170-82. PMID 16765486 DOI: 10.1016/J.Neuint.2006.04.010 |
0.808 |
|
2006 |
Won JS, Singh I. Sphingolipid signaling and redox regulation. Free Radical Biology & Medicine. 40: 1875-88. PMID 16716889 DOI: 10.1016/J.Freeradbiomed.2006.01.035 |
0.303 |
|
2006 |
Jatana M, Giri S, Ansari MA, Elango C, Singh AK, Singh I, Khan M. Inhibition of NF-kappaB activation by 5-lipoxygenase inhibitors protects brain against injury in a rat model of focal cerebral ischemia. Journal of Neuroinflammation. 3: 12. PMID 16689995 DOI: 10.1186/1742-2094-3-12 |
0.346 |
|
2006 |
Giri S, Khan M, Rattan R, Singh I, Singh AK. Krabbe disease: psychosine-mediated activation of phospholipase A2 in oligodendrocyte cell death. Journal of Lipid Research. 47: 1478-92. PMID 16645197 DOI: 10.1194/Jlr.M600084-Jlr200 |
0.651 |
|
2006 |
Jatana M, Singh I, Singh AK, Jenkins D. Combination of systemic hypothermia and N-acetylcysteine attenuates hypoxic-ischemic brain injury in neonatal rats. Pediatric Research. 59: 684-9. PMID 16627882 DOI: 10.1203/01.Pdr.0000215045.91122.44 |
0.34 |
|
2006 |
Paintlia AS, Paintlia MK, Singh I, Singh AK. IL-4-induced peroxisome proliferator-activated receptor gamma activation inhibits NF-kappaB trans activation in central nervous system (CNS) glial cells and protects oligodendrocyte progenitors under neuroinflammatory disease conditions: implication for CNS-demyelinating diseases. Journal of Immunology (Baltimore, Md. : 1950). 176: 4385-98. PMID 16547277 DOI: 10.4049/Jimmunol.176.7.4385 |
0.404 |
|
2006 |
Haq E, Contreras MA, Giri S, Singh I, Singh AK. Dysfunction of peroxisomes in twitcher mice brain: a possible mechanism of psychosine-induced disease. Biochemical and Biophysical Research Communications. 343: 229-38. PMID 16530726 DOI: 10.1016/J.Bbrc.2006.02.131 |
0.392 |
|
2006 |
Khan M, Jatana M, Elango C, Paintlia AS, Singh AK, Singh I. Cerebrovascular protection by various nitric oxide donors in rats after experimental stroke. Nitric Oxide : Biology and Chemistry / Official Journal of the Nitric Oxide Society. 15: 114-24. PMID 16524750 DOI: 10.1016/J.Niox.2006.01.008 |
0.361 |
|
2006 |
Rattan R, Giri S, Singh AK, Singh I. Rho/ROCK pathway as a target of tumor therapy. Journal of Neuroscience Research. 83: 243-55. PMID 16385577 DOI: 10.1002/Jnr.20707 |
0.618 |
|
2005 |
Rattan R, Giri S, Singh AK, Singh I. 5-Aminoimidazole-4-carboxamide-1-beta-D-ribofuranoside inhibits cancer cell proliferation in vitro and in vivo via AMP-activated protein kinase. The Journal of Biological Chemistry. 280: 39582-93. PMID 16176927 DOI: 10.1074/Jbc.M507443200 |
0.635 |
|
2005 |
Ayasolla KR, Singh AK, Singh I. 5-aminoimidazole-4-carboxamide-1-beta-4-ribofuranoside (AICAR) attenuates the expression of LPS- and Abeta peptide-induced inflammatory mediators in astroglia. Journal of Neuroinflammation. 2: 21. PMID 16174294 DOI: 10.1186/1742-2094-2-21 |
0.382 |
|
2005 |
Paintlia AS, Paintlia MK, Khan M, Vollmer T, Singh AK, Singh I. HMG-CoA reductase inhibitor augments survival and differentiation of oligodendrocyte progenitors in animal model of multiple sclerosis. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 19: 1407-21. PMID 16126908 DOI: 10.1096/Fj.05-3861Com |
0.376 |
|
2005 |
Nath N, Giri S, Prasad R, Salem ML, Singh AK, Singh I. 5-aminoimidazole-4-carboxamide ribonucleoside: a novel immunomodulator with therapeutic efficacy in experimental autoimmune encephalomyelitis. Journal of Immunology (Baltimore, Md. : 1950). 175: 566-74. PMID 15972693 DOI: 10.4049/Jimmunol.175.1.566 |
0.753 |
|
2005 |
Prasad R, Giri S, Nath N, Singh I, Singh AK. Inhibition of phosphoinositide 3 kinase-Akt (protein kinase B)-nuclear factor-kappa B pathway by lovastatin limits endothelial-monocyte cell interaction. Journal of Neurochemistry. 94: 204-14. PMID 15953363 DOI: 10.1111/J.1471-4159.2005.03182.X |
0.738 |
|
2005 |
Khan M, Haq E, Giri S, Singh I, Singh AK. Peroxisomal participation in psychosine-mediated toxicity: implications for Krabbe's disease. Journal of Neuroscience Research. 80: 845-54. PMID 15898099 DOI: 10.1002/Jnr.20529 |
0.428 |
|
2005 |
Stanislaus R, Gilg AG, Singh AK, Singh I. N-acetyl-L-cysteine ameliorates the inflammatory disease process in experimental autoimmune encephalomyelitis in Lewis rats. Journal of Autoimmune Diseases. 2: 4. PMID 15869713 DOI: 10.1186/1740-2557-2-4 |
0.8 |
|
2005 |
Won JS, Im YB, Khan M, Singh AK, Singh I. Involvement of phospholipase A2 and lipoxygenase in lipopolysaccharide-induced inducible nitric oxide synthase expression in glial cells. Glia. 51: 13-21. PMID 15779087 DOI: 10.1002/Glia.20178 |
0.376 |
|
2005 |
Pannu R, Singh AK, Singh I. A novel role of lactosylceramide in the regulation of tumor necrosis factor alpha-mediated proliferation of rat primary astrocytes. Implications for astrogliosis following neurotrauma. The Journal of Biological Chemistry. 280: 13742-51. PMID 15668227 DOI: 10.1074/Jbc.M411959200 |
0.815 |
|
2005 |
Khan M, Sekhon B, Giri S, Jatana M, Gilg AG, Ayasolla K, Elango C, Singh AK, Singh I. S-Nitrosoglutathione reduces inflammation and protects brain against focal cerebral ischemia in a rat model of experimental stroke. Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism. 25: 177-92. PMID 15647746 DOI: 10.1038/Sj.Jcbfm.9600012 |
0.794 |
|
2005 |
Lee JK, Won JS, Singh AK, Singh I. Adenosine kinase inhibitor attenuates the expression of inducible nitric oxide synthase in glial cells. Neuropharmacology. 48: 151-60. PMID 15617735 DOI: 10.1016/J.Neuropharm.2004.09.006 |
0.368 |
|
2005 |
Pannu R, Barbosa E, Singh AK, Singh I. Attenuation of acute inflammatory response by atorvastatin after spinal cord injury in rats. Journal of Neuroscience Research. 79: 340-50. PMID 15605375 DOI: 10.1002/Jnr.20345 |
0.816 |
|
2004 |
Won JS, Im YB, Singh AK, Singh I. Dual role of cAMP in iNOS expression in glial cells and macrophages is mediated by differential regulation of p38-MAPK/ATF-2 activation and iNOS stability. Free Radical Biology & Medicine. 37: 1834-44. PMID 15528042 DOI: 10.1016/J.Freeradbiomed.2004.08.017 |
0.402 |
|
2004 |
Giri S, Rattan R, Singh AK, Singh I. The 15-deoxy-delta12,14-prostaglandin J2 inhibits the inflammatory response in primary rat astrocytes via down-regulating multiple steps in phosphatidylinositol 3-kinase-Akt-NF-kappaB-p300 pathway independent of peroxisome proliferator-activated receptor gamma. Journal of Immunology (Baltimore, Md. : 1950). 173: 5196-208. PMID 15470065 DOI: 10.4049/Jimmunol.173.8.5196 |
0.656 |
|
2004 |
Paintlia MK, Paintlia AS, Barbosa E, Singh I, Singh AK. N-acetylcysteine prevents endotoxin-induced degeneration of oligodendrocyte progenitors and hypomyelination in developing rat brain. Journal of Neuroscience Research. 78: 347-61. PMID 15389835 DOI: 10.1002/Jnr.20261 |
0.381 |
|
2004 |
Singh I, Paintlia AS, Khan M, Stanislaus R, Paintlia MK, Haq E, Singh AK, Contreras MA. Impaired peroxisomal function in the central nervous system with inflammatory disease of experimental autoimmune encephalomyelitis animals and protection by lovastatin treatment. Brain Research. 1022: 1-11. PMID 15353207 DOI: 10.1016/J.Brainres.2004.06.059 |
0.788 |
|
2004 |
Pannu R, Won JS, Khan M, Singh AK, Singh I. A novel role of lactosylceramide in the regulation of lipopolysaccharide/interferon-gamma-mediated inducible nitric oxide synthase gene expression: implications for neuroinflammatory diseases. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 24: 5942-54. PMID 15229242 DOI: 10.1523/Jneurosci.1271-04.2004 |
0.818 |
|
2004 |
Ayasolla K, Khan M, Singh AK, Singh I. Inflammatory mediator and beta-amyloid (25-35)-induced ceramide generation and iNOS expression are inhibited by vitamin E. Free Radical Biology & Medicine. 37: 325-38. PMID 15223066 DOI: 10.1016/J.Freeradbiomed.2004.04.007 |
0.372 |
|
2004 |
Paintlia AS, Paintlia MK, Singh AK, Stanislaus R, Gilg AG, Barbosa E, Singh I. Regulation of gene expression associated with acute experimental autoimmune encephalomyelitis by Lovastatin. Journal of Neuroscience Research. 77: 63-81. PMID 15197739 DOI: 10.1002/Jnr.20130 |
0.785 |
|
2004 |
Khan M, Sekhon B, Jatana M, Giri S, Gilg AG, Sekhon C, Singh I, Singh AK. Administration of N-acetylcysteine after focal cerebral ischemia protects brain and reduces inflammation in a rat model of experimental stroke. Journal of Neuroscience Research. 76: 519-27. PMID 15114624 DOI: 10.1002/Jnr.20087 |
0.772 |
|
2004 |
Giri S, Nath N, Smith B, Viollet B, Singh AK, Singh I. 5-aminoimidazole-4-carboxamide-1-beta-4-ribofuranoside inhibits proinflammatory response in glial cells: a possible role of AMP-activated protein kinase. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 24: 479-87. PMID 14724246 DOI: 10.1523/Jneurosci.4288-03.2004 |
0.448 |
|
2004 |
Won JS, Im YB, Khan M, Singh AK, Singh I. The role of neutral sphingomyelinase produced ceramide in lipopolysaccharide-mediated expression of inducible nitric oxide synthase. Journal of Neurochemistry. 88: 583-93. PMID 14720208 DOI: 10.1046/J.1471-4159.2003.02165.X |
0.388 |
|
2004 |
Nath N, Giri S, Prasad R, Singh AK, Singh I. Potential targets of 3-hydroxy-3-methylglutaryl coenzyme A reductase inhibitor for multiple sclerosis therapy. Journal of Immunology (Baltimore, Md. : 1950). 172: 1273-86. PMID 14707106 DOI: 10.4049/Jimmunol.172.2.1273 |
0.746 |
|
2003 |
Paintlia AS, Gilg AG, Khan M, Singh AK, Barbosa E, Singh I. Correlation of very long chain fatty acid accumulation and inflammatory disease progression in childhood X-ALD: implications for potential therapies. Neurobiology of Disease. 14: 425-39. PMID 14678759 DOI: 10.1016/J.Nbd.2003.08.013 |
0.778 |
|
2003 |
Rattan R, Giri S, Singh AK, Singh I. Rho A negatively regulates cytokine-mediated inducible nitric oxide synthase expression in brain-derived transformed cell lines: negative regulation of IKKalpha. Free Radical Biology & Medicine. 35: 1037-50. PMID 14572607 DOI: 10.1016/S0891-5849(03)00459-3 |
0.677 |
|
2003 |
Haq E, Giri S, Singh I, Singh AK. Molecular mechanism of psychosine-induced cell death in human oligodendrocyte cell line. Journal of Neurochemistry. 86: 1428-40. PMID 12950451 DOI: 10.1046/J.1471-4159.2003.01941.X |
0.346 |
|
2003 |
Sekhon B, Sekhon C, Khan M, Patel SJ, Singh I, Singh AK. N-Acetyl cysteine protects against injury in a rat model of focal cerebral ischemia Brain Research. 971: 1-8. PMID 12691831 DOI: 10.1016/S0006-8993(03)02244-3 |
0.384 |
|
2003 |
Dobashi K, Singh I, Orak JK, Asayama K, Singh AK. Combination therapy of N-acetylcysteine, sodium nitroprusside and phosphoramidon attenuates ischemia-reperfusion injury in rat kidney. Molecular and Cellular Biochemistry. 240: 9-17. PMID 12487367 DOI: 10.1023/A:1020629020443 |
0.311 |
|
2003 |
Won J, Im Y, Key L, Singh I, Singh AK. The Involvement of Glucose Metabolism in the Regulation of Inducible Nitric Oxide Synthase Gene Expression in Glial Cells: Possible Role of Glucose-6-Phosphate Dehydrogenase and CCAAT/Enhancing Binding Protein The Journal of Neuroscience. 23: 7470-7478. DOI: 10.1523/Jneurosci.23-20-07470.2003 |
0.317 |
|
2002 |
Kaul P, Singh I, Turner RB. Effect of rhinovirus challenge on antioxidant enzymes in respiratory epithelial cells. Free Radical Research. 36: 1085-9. PMID 12516880 DOI: 10.1080/1071576021000028316 |
0.368 |
|
2002 |
Stanislaus R, Gilg AG, Singh AK, Singh I. Immunomodulation of experimental autoimmune encephalomyelitis in the Lewis rats by Lovastatin. Neuroscience Letters. 333: 167-70. PMID 12429374 DOI: 10.1016/S0304-3940(02)00943-6 |
0.79 |
|
2002 |
Giri S, Jatana M, Rattan R, Won JS, Singh I, Singh AK. Galactosylsphingosine (psychosine)-induced expression of cytokine-mediated inducible nitric oxide synthases via AP-1 and C/EBP: implications for Krabbe disease. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 16: 661-72. PMID 11978730 DOI: 10.1096/Fj.01-0798Com |
0.66 |
|
2002 |
Singh I, Kremser K, Ghosh B, Singh AK, Pai S. Abnormality in translational regulation of catalase expression in disorders of peroxisomal biogenesis. Journal of Neurochemistry. 67: 2373-2378. PMID 8931469 DOI: 10.1046/J.1471-4159.1996.67062373.X |
0.305 |
|
2001 |
Stanislaus R, Singh AK, Singh I. Lovastatin treatment decreases mononuclear cell infiltration into the CNS of Lewis rats with experimental allergic encephalomyelitis. Journal of Neuroscience Research. 66: 155-62. PMID 11592110 DOI: 10.1002/Jnr.1207 |
0.787 |
|
2000 |
Gilg AG, Singh AK, Singh I. Inducible nitric oxide synthase in the central nervous system of patients with X-adrenoleukodystrophy. Journal of Neuropathology and Experimental Neurology. 59: 1063-9. PMID 11138926 DOI: 10.1093/Jnen/59.12.1063 |
0.765 |
|
2000 |
Khan M, Contreras M, Singh I. Endotoxin-induced alterations of lipid and fatty acid compositions in rat liver peroxisomes. Journal of Endotoxin Research. 6: 41-50. PMID 11061031 DOI: 10.1177/09680519000060010601 |
0.307 |
|
2000 |
Pahan K, Khan M, Singh I. Interleukin-10 and interleukin-13 inhibit proinflammatory cytokine-induced ceramide production through the activation of phosphatidylinositol 3-kinase. Journal of Neurochemistry. 75: 576-82. PMID 10899932 DOI: 10.1046/J.1471-4159.2000.0750576.X |
0.32 |
|
2000 |
Pai GS, Khan M, Barbosa E, Key LL, Craver JR, Curé JK, Betros R, Singh I. Lovastatin therapy for X-linked adrenoleukodystrophy: clinical and biochemical observations on 12 patients. Molecular Genetics and Metabolism. 69: 312-22. PMID 10870849 DOI: 10.1006/Mgme.2000.2977 |
0.331 |
|
2000 |
Kaul P, Biagioli MC, Singh I, Turner RB. Rhinovirus-induced oxidative stress and interleukin-8 elaboration involves p47-phox but is independent of attachment to intercellular adhesion molecule-1 and viral replication. The Journal of Infectious Diseases. 181: 1885-90. PMID 10837166 DOI: 10.1086/315504 |
0.323 |
|
2000 |
Dobashi K, Ghosh B, Orak JK, Singh I, Singh AK. Kidney ischemia-reperfusion: modulation of antioxidant defenses. Molecular and Cellular Biochemistry. 205: 1-11. PMID 10821417 DOI: 10.1023/A:1007047505107 |
0.341 |
|
2000 |
Singh I, Carillo O, Namboodiri A. Isolation and biochemical characterization of peroxisomes from cultured rat glial cells. Neurochemical Research. 25: 197-203. PMID 10786702 DOI: 10.1023/A:1007563201595 |
0.355 |
|
2000 |
Contreras MA, Khan M, Smith BT, Cimini AM, Gilg AG, Orak J, Singh I, Singh AK. Endotoxin induces structure-function alterations of rat liver peroxisomes: Kupffer cells released factors as possible modulators. Hepatology (Baltimore, Md.). 31: 446-55. PMID 10655269 DOI: 10.1002/Hep.510310226 |
0.765 |
|
1999 |
Singh AK, Dobashi K, Gupta MP, Asayama K, Singh I, Orak JK. Manganese superoxide dismutase in rat liver peroxisomes: biochemical and immunochemical evidence. Molecular and Cellular Biochemistry. 197: 7-12. PMID 10485318 DOI: 10.1023/A:1006848113499 |
0.32 |
|
1999 |
Stanislaus R, Pahan K, Singh AK, Singh I. Amelioration of experimental allergic encephalomyelitis in Lewis rats by lovastatin. Neuroscience Letters. 269: 71-4. PMID 10430507 DOI: 10.1016/S0304-3940(99)00414-0 |
0.789 |
|
1999 |
Pahan K, Dobashi K, Ghosh B, Singh I. Induction of the manganese superoxide dismutase gene by sphingomyelinase and ceramide. Journal of Neurochemistry. 73: 513-20. PMID 10428046 DOI: 10.1046/J.1471-4159.1999.0730513.X |
0.385 |
|
1999 |
Asayama K, Sandhir R, Sheikh FG, Hayashibe H, Nakane T, Singh I. Increased peroxisomal fatty acid beta-oxidation and enhanced expression of peroxisome proliferator-activated receptor-alpha in diabetic rat liver. Molecular and Cellular Biochemistry. 194: 227-34. PMID 10391144 DOI: 10.1023/A:1006930513476 |
0.309 |
|
1999 |
Pahan K, Raymond JR, Singh I. Inhibition of phosphatidylinositol 3-kinase induces nitric-oxide synthase in lipopolysaccharide- or cytokine-stimulated C6 glial cells. The Journal of Biological Chemistry. 274: 7528-36. PMID 10066820 DOI: 10.1074/Jbc.274.11.7528 |
0.385 |
|
1999 |
Biagioli MC, Kaul P, Singh I, Turner RB. The role of oxidative stress in rhinovirus induced elaboration of IL-8 by respiratory epithelial cells. Free Radical Biology & Medicine. 26: 454-62. PMID 9895238 DOI: 10.1016/S0891-5849(98)00233-0 |
0.33 |
|
1998 |
Singh I, Khan M, Key L, Pai S. Lovastatin for X-linked adrenoleukodystrophy. The New England Journal of Medicine. 339: 702-3. PMID 9729143 DOI: 10.1056/Nejm199809033391012 |
0.3 |
|
1998 |
Singh I, Pahan K, Khan M, Singh AK. Cytokine-mediated induction of ceramide production is redox-sensitive. Implications to proinflammatory cytokine-mediated apoptosis in demyelinating diseases. The Journal of Biological Chemistry. 273: 20354-62. PMID 9685387 DOI: 10.1074/Jbc.273.32.20354 |
0.451 |
|
1998 |
Khan M, Pahan K, Singh AK, Singh I. Cytokine-induced accumulation of very long-chain fatty acids in rat C6 glial cells: implication for X-adrenoleukodystrophy. Journal of Neurochemistry. 71: 78-87. PMID 9648853 DOI: 10.1046/J.1471-4159.1998.71010078.X |
0.436 |
|
1998 |
Pahan K, Sheikh FG, Namboodiri AM, Singh I. Inhibitors of protein phosphatase 1 and 2A differentially regulate the expression of inducible nitric-oxide synthase in rat astrocytes and macrophages. The Journal of Biological Chemistry. 273: 12219-26. PMID 9575170 DOI: 10.1074/Jbc.273.20.12219 |
0.41 |
|
1998 |
Sheikh FG, Pahan K, Khan M, Barbosa E, Singh I. Abnormality in catalase import into peroxisomes leads to severe neurological disorder. Proceedings of the National Academy of Sciences of the United States of America. 95: 2961-6. PMID 9501198 DOI: 10.1073/Pnas.95.6.2961 |
0.327 |
|
1998 |
Pahan K, Sheikh FG, Khan M, Namboodiri AM, Singh I. Sphingomyelinase and ceramide stimulate the expression of inducible nitric-oxide synthase in rat primary astrocytes. The Journal of Biological Chemistry. 273: 2591-600. PMID 9446561 DOI: 10.1074/Jbc.273.5.2591 |
0.377 |
|
1998 |
Pahan K, Sheikh FG, Namboodiri AMS, Singh I. N-acetyl cysteine inhibits induction of no production by endotoxin or cytokine stimulated rat peritoneal macrophages, C6 glial cells and astrocytes Free Radical Biology and Medicine. 24: 39-48. PMID 9436612 DOI: 10.1016/S0891-5849(97)00137-8 |
0.407 |
|
1997 |
Pahan K, Sheikh FG, Namboodiri AM, Singh I. Lovastatin and phenylacetate inhibit the induction of nitric oxide synthase and cytokines in rat primary astrocytes, microglia, and macrophages. The Journal of Clinical Investigation. 100: 2671-9. PMID 9389730 DOI: 10.1172/Jci119812 |
0.42 |
|
1997 |
Pahan K, Smith BT, Singh AK, Singh I. Cytochrome P-450 2E1 in rat liver peroxisomes: Downregulation by ischemia/reperfusion-induced oxidative stress Free Radical Biology and Medicine. 23: 963-971. PMID 9358238 DOI: 10.1016/S0891-5849(97)00017-8 |
0.324 |
|
1997 |
Singh I, Voigt RG, Sheikh FG, Kremser K, Brown FR. Biochemical features of a patient with Zellweger-like syndrome with normal PTS-1 and PTS-2 peroxisomal protein import systems: a new peroxisomal disease. Biochemical and Molecular Medicine. 61: 198-207. PMID 9259985 DOI: 10.1006/Bmme.1997.2593 |
0.32 |
|
1997 |
Dobashi K, Pahan K, Chahal A, Singh I. Modulation of endogenous antioxidant enzymes by nitric oxide in rat C6 glial cells Journal of Neurochemistry. 68: 1896-1903. PMID 9109515 DOI: 10.1046/J.1471-4159.1997.68051896.X |
0.407 |
|
1997 |
Pahan K, Namboodiri AMS, Sheikh FG, Smith BT, Singh I. Increasing cAMP attenuates induction of inducible nitric-oxide synthase in rat primary astrocytes Journal of Biological Chemistry. 272: 7786-7791. PMID 9065441 DOI: 10.1074/Jbc.272.12.7786 |
0.418 |
|
1997 |
Dobashi K, Pahan K, Chahal A, Singh I. Modulation of Endogenous Antioxidant Enzymes by Nitric Oxide in Rat C6 Glial Cells † 1722 Pediatric Research. 41: 289-289. DOI: 10.1203/00006450-199704001-01741 |
0.408 |
|
1997 |
Biagioli MC, Kaul P, Singh I, Turner RB. Rhinovirus (RV)-Induced Interleukin-8 (IL-8) Production in Respiratory Epithelial Cells is Mediated by H2O2 and is Inhibited by N-Acetyl Cysteine (NAC) † 690 Pediatric Research. 41: 117-117. DOI: 10.1203/00006450-199704001-00710 |
0.318 |
|
1997 |
Khan M, Contreras M, Singh I. KUPFFER CELLS MODULATE THE LIPOPOLYSACCHARIDE-INDUCED LIPID ALTERATIONS IN RAT LIVER PEROXISOMES. 610 Pediatric Research. 41: 104-104. DOI: 10.1203/00006450-199704001-00630 |
0.319 |
|
1996 |
Burdette DE, Kremser K, Fink JK, Pahan K, Stanley W, Singh I. Late-onset generalized disorder of peroxisomes Neurology. 46: 829-831. PMID 8618694 DOI: 10.1212/Wnl.46.3.829 |
0.3 |
|
1995 |
Kremser K, Stangl H, Pahan K, Singh I. Nitric oxide regulates peroxisomal enzyme activities. European Journal of Clinical Chemistry and Clinical Biochemistry : Journal of the Forum of European Clinical Chemistry Societies. 33: 763-74. PMID 8620052 DOI: 10.1515/Cclm.1995.33.11.763 |
0.327 |
|
1995 |
Pahan K, Khan M, Smith BT, Singh I. Ketoconazole and other imidazole derivatives are potent inhibitors of peroxisomal phytanic acid α-oxidation Febs Letters. 377: 213-216. PMID 8543053 DOI: 10.1016/0014-5793(95)01341-5 |
0.323 |
|
1995 |
Kremser K, Kremser-Jezik M, Singh I. Effect of hypoxia-reoxygenation on peroxisomal functions in cultured human skin fibroblasts from control and Zellweger syndrome patients. Free Radical Research. 22: 39-46. PMID 7889146 DOI: 10.3109/10715769509147526 |
0.336 |
|
1995 |
Dhaunsi GS, Hanevold CD, Singh I. Impairment of peroxisomal beta-oxidation system by endotoxin treatment. Molecular and Cellular Biochemistry. 135: 187-93. PMID 7838145 DOI: 10.1007/Bf00926522 |
0.335 |
|
1994 |
Singh I, Gulati S, Orak JK, Singh AK. Expression of antioxidant enzymes in rat kidney during ischemia-reperfusion injury. Molecular and Cellular Biochemistry. 125: 97-104. PMID 8283974 DOI: 10.1007/Bf00936438 |
0.346 |
|
1994 |
Dhaunsi GS, Singh I, Hanevold CD. Peroxisomal participation in the cellular response to the oxidative stress of endotoxin. Molecular and Cellular Biochemistry. 126: 25-35. PMID 8107687 DOI: 10.1007/Bf01772205 |
0.355 |
|
1994 |
Singh AK, Dhaunsi GS, Gupta MP, Orak JK, Asayama K, Singh I. Demonstration of Glutathione Peroxidase in Rat Liver Peroxisomes and Its Intraorganellar Distribution Archives of Biochemistry and Biophysics. 315: 331-338. PMID 7986075 DOI: 10.1006/Abbi.1994.1508 |
0.326 |
|
1994 |
Dhaunsi GS, Singh I, Orak JK, Singh AK. Antioxidant enzymes in ciprofibrate-induced oxidative stress Carcinogenesis. 15: 1923-1930. PMID 7923586 DOI: 10.1093/Carcin/15.9.1923 |
0.349 |
|
1994 |
Pahan K, Gulati S, Singh I. Phytanic acid α-oxidation in rat liver mitochondria Bba - General Subjects. 1201: 491-497. PMID 7803482 DOI: 10.1016/0304-4165(94)90081-7 |
0.321 |
|
1993 |
Pahan K, Cofer J, Baliga P, Singh I. Identification of phytanoyl-CoA ligase as a distinct acyl-CoA ligase in peroxisomes from cultured human skin fibroblasts Febs Letters. 322: 101-104. PMID 8482375 DOI: 10.1016/0014-5793(93)81546-C |
0.312 |
|
1993 |
Gulati S, Ainol L, Orak J, Singh AK, Singh I. Alterations of peroxisomal function in ischemia-reperfusion injury of rat kidney Biochimica Et Biophysica Acta. 1182: 291-298. PMID 8399363 DOI: 10.1016/0925-4439(93)90071-8 |
0.327 |
|
1993 |
Singh I, Lazo O, Kremser K. Purification of peroxisomes and subcellular distribution of enzyme activities for activation and oxidation of very-long-chain fatty acids in rat brain Biochimica Et Biophysica Acta (Bba)/Lipids and Lipid Metabolism. 1170: 44-52. PMID 8399326 DOI: 10.1016/0005-2760(93)90174-8 |
0.342 |
|
1993 |
Dhaunsi GS, Singh B, Singh AK, Kirschner DA, Singh I. Thioridazine induces lipid peroxidation in myelin of rat brain. Neuropharmacology. 32: 157-67. PMID 8383815 DOI: 10.1016/0028-3908(93)90096-L |
0.344 |
|
1993 |
Aubourg P, Kremser K, Roland MO, Rocchiccioli F, Singh I. Pseudo infantile Refsum's disease : catalase-deficient peroxisomal particles with partial deficiency of plasmalogen synthesis and oxidation of fatty acids Pediatric Research. 34: 270-276. PMID 7510868 DOI: 10.1203/00006450-199309000-00006 |
0.303 |
|
1993 |
Gulati S, Singh I, Orak JK, Singh AK. Expression of antioxidant enzymes in rat kidney during ischemia-reperfusion injury Free Radical Biology and Medicine. 15: 545. DOI: 10.1016/0891-5849(93)90462-4 |
0.324 |
|
1992 |
Singh I, Lazo O. Peroxisomal enzyme activities in brain and liver of pups of lactating mothers treated with ciprofibrate Neuroscience Letters. 138: 283-286. PMID 1608540 DOI: 10.1016/0304-3940(92)90934-Y |
0.32 |
|
1992 |
Gulati S, Singh AK, Irazu C, Orak J, Rajagopalan PR, Fitts CT, Singh I. Ischemia-reperfusion injury: Biochemical alterations in peroxisomes of rat kidney Archives of Biochemistry and Biophysics. 295: 90-100. PMID 1575521 DOI: 10.1016/0003-9861(92)90492-F |
0.325 |
|
1991 |
Lazo O, Contreras M, Singh I. Effect of ciprofibrate on the activation and oxidation of very long chain fatty acids Molecular and Cellular Biochemistry. 100: 159-167. PMID 2008177 DOI: 10.1007/Bf00234165 |
0.313 |
|
1991 |
Lazo O, Singh AK, Singh I. Postnatal development and isolation of peroxisomes from brain Journal of Neurochemistry. 56: 1343-1353. PMID 2002347 DOI: 10.1111/J.1471-4159.1991.Tb11431.X |
0.34 |
|
1991 |
Singh I, Stanley W, Hashimoto T, Lazo O, Contreras M. Rhizomelic chondrodysplasia punctata: Biochemical studies of peroxisomes isolated from cultured skin fibroblasts Archives of Biochemistry and Biophysics. 286: 277-283. PMID 1680308 DOI: 10.1016/0003-9861(91)90041-G |
0.305 |
|
1990 |
Yoshida Y, Singh I. Effect of clofibrate on peroxisomal lignoceroyl-CoA ligase activity Biochemical Medicine and Metabolic Biology. 43: 22-29. PMID 2310609 DOI: 10.1016/0885-4505(90)90004-K |
0.315 |
|
1990 |
Singh I, Lazo O, Contreras M, Stanley W. 73 Rhizomelic Chondrodysplasia Punctata: Metabolic Studies in Isolated Peroxisomes Pediatric Research. 28: 289-289. DOI: 10.1203/00006450-199009000-00097 |
0.312 |
|
1989 |
Lazo O, Contreras M, Bhushan A, Stanley W, Singh I. Adrenoleukodystrophy: Impaired oxidation of fatty acids due to peroxisomal lignoceroyl-CoA ligase deficiency Archives of Biochemistry and Biophysics. 270: 722-728. PMID 2705786 DOI: 10.1016/0003-9861(89)90555-9 |
0.311 |
|
1988 |
Lazo O, Contreras M, Hashmi M, Stanley W, Irazu C, Singh I. Peroxisomal lignoceroyl-CoA ligase deficiency in childhood adrenoleukodystrophy and adrenomyeloneuropathy Proceedings of the National Academy of Sciences of the United States of America. 85: 7647-7651. PMID 3174658 DOI: 10.1073/Pnas.85.20.7647 |
0.302 |
|
1986 |
Singh RP, Singh I. Peroxisomal oxidation of lignoceric acid in rat brain. Neurochemical Research. 11: 281-9. PMID 3703106 DOI: 10.1007/Bf00967975 |
0.319 |
|
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