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Senthil K. Karunakaran, Ph.D. - Publications

Affiliations: 
2010 Medical College of Georgia, Augusta, GA, United States 
Area:
Molecular Biology, Biochemistry, Cell Biology
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6 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2011 Karunakaran S, Ramachandran S, Coothankandaswamy V, Elangovan S, Babu E, Periyasamy-Thandavan S, Gurav A, Gnanaprakasam JP, Singh N, Schoenlein PV, Prasad PD, Thangaraju M, Ganapathy V. SLC6A14 (ATB0,+) protein, a highly concentrative and broad specific amino acid transporter, is a novel and effective drug target for treatment of estrogen receptor-positive breast cancer. The Journal of Biological Chemistry. 286: 31830-8. PMID 21771784 DOI: 10.1074/Jbc.M111.229518  0.589
2011 Ganapathy V, Karunakaran S, Ramachandran S, Babu E, Elangovan S, Periaswamy-Thandavan S, Schoenlein PV, Gurav A, Singh N, Prasad PD, Thangaraju M. Abstract 4459: a-Methyltryptophan (a-MT) inhibits estrogen receptor (ER)-positive breast cancer growth through blockade of SLC6A14 Cancer Research. 71: 4459-4459. DOI: 10.1158/1538-7445.Am2011-4459  0.558
2010 Karunakaran S, Schoenlein PV, Thangaraju M, Prasad PD, Ganapathy V. Abstract 4838: Alpha-methyltryptophan, a blocker of the amino acid transporter SLC6A14, induces autophagy and apoptosis in SLC6A14-positive breast cancer and colon cancer cell lines Cancer Research. 70: 4838-4838. DOI: 10.1158/1538-7445.Am10-4838  0.591
2009 Thangaraju M, Karunakaran SK, Itagaki S, Gopal E, Elangovan S, Prasad PD, Ganapathy V. Transport by SLC5A8 with subsequent inhibition of histone deacetylase 1 (HDAC1) and HDAC3 underlies the antitumor activity of 3-bromopyruvate. Cancer. 115: 4655-66. PMID 19637353 DOI: 10.1002/Cncr.24532  0.404
2009 Ananth S, Karunakaran S, Martin PM, Nagineni CN, Hooks JJ, Smith SB, Prasad PD, Ganapathy V. Functional identification of a novel transport system for endogenous and synthetic opioid peptides in the rabbit conjunctival epithelial cell line CJVE. Pharmaceutical Research. 26: 1226-35. PMID 18781380 DOI: 10.1007/S11095-008-9709-X  0.448
2008 Karunakaran S, Umapathy NS, Thangaraju M, Hatanaka T, Itagaki S, Munn DH, Prasad PD, Ganapathy V. Interaction of tryptophan derivatives with SLC6A14 (ATB0,+) reveals the potential of the transporter as a drug target for cancer chemotherapy. The Biochemical Journal. 414: 343-55. PMID 18522536 DOI: 10.1042/Bj20080622  0.564
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