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Julien A. Sebag, Ph.D. - Publications

Affiliations: 
2009 University of Rochester, Rochester, NY 
Area:
Pharmacology, Physiology Biology, Cell Biology
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26 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2022 Yin TC, Mittal A, Buscaglia P, Li W, Sebag JA. Activation of Amygdala Prokineticin receptor 2 neurons drives the anorexigenic activity of the neuropeptide PK2. The Journal of Biological Chemistry. 102814. PMID 36539034 DOI: 10.1016/j.jbc.2022.102814  0.359
2022 Rouault AAJ, Buscaglia P, Sebag JA. MRAP2 inhibits β-arrestin recruitment to the ghrelin receptor by preventing GHSR1a phosphorylation. The Journal of Biological Chemistry. 102057. PMID 35605660 DOI: 10.1016/j.jbc.2022.102057  0.369
2021 Verdinez JA, Sebag JA. Role of N-Linked Glycosylation in PKR2 Trafficking and Signaling. Frontiers in Neuroscience. 15: 730417. PMID 34483834 DOI: 10.3389/fnins.2021.730417  0.372
2020 Yin TC, Bauchle CJ, Rouault AAJ, Stephens SB, Sebag JA. The Insulinostatic Effect of Ghrelin Requires MRAP2 Expression in δ Cells. Iscience. 23: 101216. PMID 32535024 DOI: 10.1016/J.Isci.2020.101216  0.38
2020 Rouault AAJ, Rosselli-Murai LK, Hernandez CC, Gimenez LE, Tall GG, Sebag JA. The GPCR accessory protein MRAP2 regulates both biased signaling and constitutive activity of the ghrelin receptor GHSR1a. Science Signaling. 13. PMID 31911434 DOI: 10.1126/Scisignal.Aax4569  0.404
2019 Perschbacher KJ, Deng G, Sandgren JA, Walsh JW, Witcher PC, Sapouckey SA, Owens CE, Zhang SY, Scroggins SM, Pearson NA, Devor EJ, Sebag JA, Pierce GL, Fisher RA, Kwitek AE, et al. Reduced mRNA Expression of RGS2 (Regulator of G Protein Signaling-2) in the Placenta Is Associated With Human Preeclampsia and Sufficient to Cause Features of the Disorder in Mice. Hypertension (Dallas, Tex. : 1979). HYPERTENSIONAHA11914. PMID 31865781 DOI: 10.1161/Hypertensionaha.119.14056  0.345
2018 Deng G, Sapouckey SA, Warwick CA, Usachev YM, Sebag JA, Cui H, Grobe JL. Abstract P190: The Angiotensin AT 1A Receptor Couples to G-alpha-i inAgouti-Related Peptide-ExpressingNeurons to Control Resting Metabolic Rate Hypertension. 72. DOI: 10.1161/Hyp.72.Suppl_1.P190  0.358
2018 Seara F, Nakagawa P, Gomez JA, Deng G, Sebag JA, Karnik SS, Grobe JL, Sigmund CD. Abstract 104: DOCA Induced Natriorexigenic and Hypertensive Effects are Blunted by Central Infusion of AT1 Receptor Biased Agonist TRV120027 Hypertension. 72. DOI: 10.1161/Hyp.72.Suppl_1.104  0.509
2017 Srisai D, Yin TC, Lee AA, Rouault AAJ, Pearson NA, Grobe JL, Sebag JA. MRAP2 regulates ghrelin receptor signaling and hunger sensing. Nature Communications. 8: 713. PMID 28959025 DOI: 10.1038/S41467-017-00747-6  0.631
2017 Rouault AAJ, Lee AA, Sebag JA. Regions of MRAP2 required for the inhibition of orexin and prokineticin receptor signaling. Biochimica Et Biophysica Acta. PMID 28939058 DOI: 10.1016/J.Bbamcr.2017.09.008  0.577
2017 Rouault AAJ, Srinivasan DK, Yin TC, Lee AA, Sebag JA. Melanocortin Receptor Accessory Proteins (MRAPs): Functions in the Melanocortin System and Beyond. Biochimica Et Biophysica Acta. PMID 28499989 DOI: 10.1016/J.Bbadis.2017.05.008  0.621
2016 Chaly AL, Srisai D, Gardner EE, Sebag JA. The Melanocortin Receptor Accessory Protein 2 promotes food intake through inhibition of the Prokineticin Receptor-1. Elife. 5. PMID 26829592 DOI: 10.7554/Elife.12397  0.469
2015 Ghamari-Langroudi M, Digby GJ, Sebag JA, Millhauser GL, Palomino R, Matthews R, Gillyard T, Panaro BL, Tough IR, Cox HM, Denton JS, Cone RD. G-protein-independent coupling of MC4R to Kir7.1 in hypothalamic neurons. Nature. 520: 94-8. PMID 25600267 DOI: 10.1038/Nature14051  0.493
2015 Chaly AL, Srisai D, Gardner EE, Sebag JA. Author response: The Melanocortin Receptor Accessory Protein 2 promotes food intake through inhibition of the Prokineticin Receptor-1 Elife. DOI: 10.7554/Elife.12397.012  0.562
2013 Sebag JA, Zhang C, Hinkle PM, Bradshaw AM, Cone RD. Developmental control of the melanocortin-4 receptor by MRAP2 proteins in zebrafish. Science (New York, N.Y.). 341: 278-81. PMID 23869017 DOI: 10.1126/Science.1232995  0.699
2011 Liang L, Sebag JA, Eagelston L, Serasinghe MN, Veo K, Reinick C, Angleson J, Hinkle PM, Dores RM. Functional expression of frog and rainbow trout melanocortin 2 receptors using heterologous MRAP1s General and Comparative Endocrinology. 174: 5-14. PMID 21846469 DOI: 10.1016/J.Ygcen.2011.07.005  0.69
2011 Pantel J, Williams SY, Mi D, Sebag J, Corbin JD, Weaver CD, Cone RD. Development of a high throughput screen for allosteric modulators of melanocortin-4 receptor signaling using a real time cAMP assay. European Journal of Pharmacology. 660: 139-47. PMID 21296065 DOI: 10.1016/J.Ejphar.2011.01.031  0.538
2011 Hinkle PM, Serasinghe MN, Jakabowski A, Sebag JA, Wilson KR, Haskell-Luevano C. Use of chimeric melanocortin-2 and -4 receptors to identify regions responsible for ligand specificity and dependence on melanocortin 2 receptor accessory protein. European Journal of Pharmacology. 660: 94-102. PMID 21211532 DOI: 10.1016/J.Ejphar.2010.10.113  0.75
2011 Renquist BJ, Lippert RN, Sebag JA, Ellacott KL, Cone RD. Physiological roles of the melanocortin MC₃ receptor. European Journal of Pharmacology. 660: 13-20. PMID 21211527 DOI: 10.1016/J.Ejphar.2010.12.025  0.613
2010 Sebag JA, Hinkle PM. Regulation of G protein-coupled receptor signaling: specific dominant-negative effects of melanocortin 2 receptor accessory protein 2. Science Signaling. 3: ra28. PMID 20371771 DOI: 10.1126/Scisignal.2000593  0.703
2009 Sebag JA, Hinkle PM. Opposite effects of the melanocortin-2 (MC2) receptor accessory protein MRAP on MC2 and MC5 receptor dimerization and trafficking. The Journal of Biological Chemistry. 284: 22641-8. PMID 19535343 DOI: 10.1074/Jbc.M109.022400  0.74
2009 Hinkle PM, Sebag JA. Structure and function of the melanocortin2 receptor accessory protein (MRAP). Molecular and Cellular Endocrinology. 300: 25-31. PMID 19028547 DOI: 10.1016/J.Mce.2008.10.041  0.752
2009 Sebag JA, Hinkle PM. Regions of melanocortin 2 (MC2) receptor accessory protein necessary for dual topology and MC2 receptor trafficking and signaling. The Journal of Biological Chemistry. 284: 610-8. PMID 18981183 DOI: 10.1074/Jbc.M804413200  0.74
2008 Sebag ja, Hinkle PM. Determinants of the unique antiparallel homodimer structure of MRAP The Faseb Journal. 22: 629-629. DOI: 10.1096/Fasebj.22.2_Supplement.629  0.511
2007 Sebag JA, Hinkle PM. Melanocortin-2 receptor accessory protein MRAP forms antiparallel homodimers. Proceedings of the National Academy of Sciences of the United States of America. 104: 20244-9. PMID 18077336 DOI: 10.1073/Pnas.0708916105  0.71
2006 Sebag JA, Hinkle PM. Regulation of endogenous melanocortin-4 receptor expression and signaling by glucocorticoids. Endocrinology. 147: 5948-55. PMID 16973723 DOI: 10.1210/En.2006-0984  0.731
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