Hartmut Derendorf - Publications

Affiliations: 
University of Florida, Gainesville, Gainesville, FL, United States 
Area:
Pharmacology, Microbiology Biology

271 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2021 Rayner CR, Smith PF, Andes D, Andrews K, Derendorf H, Friberg LE, Hanna D, Lepak A, Mills E, Polasek TM, Roberts JA, Schuck V, Shelton MJ, Wesche D, Rowland-Yeo K. Model-Informed Drug Development for Anti-Infectives: State of the Art and Future. Clinical Pharmacology and Therapeutics. PMID 33555032 DOI: 10.1002/cpt.2198  0.764
2020 do Nascimento SB, de Lima Nascimento M, de Araújo LL, de Oliveira FM, do Carmo Vieira M, Duarte-Almeida JM, Siqueira JM, da Costa César I, Derendorf H, de Castro WV. Evaluation of the effects of Maytenus ilicifolia on the activities of cytochrome P450 3A and P-glycoprotein. Current Drug Metabolism. PMID 32394829 DOI: 10.2174/1389200221666200512112718  0.3
2020 Derendorf H. Excessive lysosomal ion-trapping of hydroxychloroquine and azithromycin. International Journal of Antimicrobial Agents. 106007. PMID 32389720 DOI: 10.1016/J.Ijantimicag.2020.106007  0.367
2020 Galvão JG, Santos RL, Silva ARST, Santos JS, Costa AMB, Chandasana H, Neto VVA, Santos ECT, Lira AAM, Dolabella S, Scher R, Kima PE, Derendorf H, Nunes RS. Carvacrol loaded nanostructured lipid carriers as a promising parenteral formulation for leishmaniasis treatment. European Journal of Pharmaceutical Sciences : Official Journal of the European Federation For Pharmaceutical Sciences. 105335. PMID 32272211 DOI: 10.1016/J.Ejps.2020.105335  0.339
2019 Voelkner NMF, Voelkner A, Derendorf H. Determination of Dermal Pharmacokinetics by Microdialysis Sampling in Rats. Current Protocols in Pharmacology. e58. PMID 31026128 DOI: 10.1002/Cpph.58  0.372
2019 Derendorf H, von Richter O, Hermann R, Rostami-Hodjegan A. Drug-Drug Interactions: Progress Over the Past Decade and Looking Ahead to the Future. Clinical Pharmacology and Therapeutics. PMID 30977519 DOI: 10.1002/Cpt.1410  0.3
2019 Broeker A, Nardecchia M, Klinker KP, Derendorf H, Day RO, Marriott DJ, Carland JE, Stocker SL, Wicha SG. Towards precision dosing of vancomycin: A systematic evaluation of pharmacometric models for Bayesian forecasting. Clinical Microbiology and Infection : the Official Publication of the European Society of Clinical Microbiology and Infectious Diseases. PMID 30872102 DOI: 10.1016/J.Cmi.2019.02.029  0.394
2019 Yu G, Zheng Y, Yu Y, Li GF, Derendorf H. Gastric-acid-mediated drug-drug interactions with direct-acting antiviral medications for hepatitis C virus infection: clinical relevance and mitigation strategies. Drug Discovery Today. PMID 30648608 DOI: 10.1016/J.Drudis.2019.01.003  0.323
2019 Prasanchaimontri IO, Chandasana H, Akbar MA, Swarts S, Okuneiff P, Derendorf H. Bioanalytical method development and validation for determination of fibroblast growth factor peptide and its application to pharmacokinetic studies. European Journal of Pharmaceutics and Biopharmaceutics : Official Journal of Arbeitsgemeinschaft Fur Pharmazeutische Verfahrenstechnik E.V. 135: 83-93. PMID 30582960 DOI: 10.1016/J.Ejpb.2018.12.011  0.324
2019 Vorbach BS, Chandasana H, Derendorf H, Yanong RP. Pharmacokinetics of Oxytetracycline in the Giant Danio (Devario aequipinnatus) following bath immersion Aquaculture. 498: 12-16. DOI: 10.1016/J.Aquaculture.2018.08.027  0.379
2018 Sy SKB, Zhuang L, Xia H, Schuck VJ, Nichols WW, Derendorf H. A model-based analysis of pharmacokinetic-pharmacodynamic (PK/PD) indices of avibactam against Pseudomonas aeruginosa. Clinical Microbiology and Infection : the Official Publication of the European Society of Clinical Microbiology and Infectious Diseases. PMID 30394361 DOI: 10.1016/J.Cmi.2018.10.014  0.761
2018 Heinrichs MT, Drusano GL, Brown DL, Maynard MS, Sy SKB, Rand KH, Peloquin CA, Louie A, Derendorf H. Dose Optimization of Moxifloxacin and Linezolid Against Tuberculosis Using Mathematical Modeling and Simulation. International Journal of Antimicrobial Agents. PMID 30385322 DOI: 10.1016/J.Ijantimicag.2018.10.012  0.335
2018 Sy SKB, Zhuang L, Sy S, Derendorf H. Clinical Pharmacokinetics and Pharmacodynamics of Ceftazidime-Avibactam Combination: A Model-Informed Strategy for its Clinical Development. Clinical Pharmacokinetics. PMID 30097887 DOI: 10.1007/S40262-018-0705-Y  0.408
2018 Ravula A, Chandasana H, Setlow B, Febo M, Bruijnzeel AW, Derendorf H. Simultaneous quantification of cannabinoids tetrahydrocannabinol, cannabidiol and CB1 receptor antagonist in rat plasma: An application to characterize pharmacokinetics after passive cannabis smoke inhalation and co-administration of rimonabant. Journal of Pharmaceutical and Biomedical Analysis. 160: 119-125. PMID 30077950 DOI: 10.1016/J.Jpba.2018.07.004  0.355
2018 Chandasana H, Kast J, Bittman JA, Derendorf H. Quantitative determination of armodafinil in human plasma by liquid chromatography-electrospray mass spectrometry: Application to a clinical study. Biomedical Chromatography : Bmc. e4342. PMID 30003558 DOI: 10.1002/Bmc.4342  0.337
2018 Yu Y, Chandasana H, Sangari T, Seubert C, Derendorf H. Simultaneous retrodialysis by calibrator for rapid in vivo recovery determination in target site microdialysis. Journal of Pharmaceutical Sciences. PMID 29715477 DOI: 10.1016/J.Xphs.2018.04.021  0.313
2018 Deitchman AN, Singh RSP, Derendorf H. Pharmacokinetics, Pharmacodynamics and Drug Transport and Metabolism Nonlinear Protein Binding: Not What You Think. Journal of Pharmaceutical Sciences. PMID 29626534 DOI: 10.1016/J.Xphs.2018.03.023  0.344
2018 Li GF, Yu G, Li Y, Zheng Y, Zheng QS, Derendorf H. Quantitative estimation of plasma free drug fraction in patients with varying degrees of hepatic impairment: a methodological evaluation. Journal of Pharmaceutical Sciences. PMID 29518400 DOI: 10.1016/J.Xphs.2018.02.021  0.317
2018 Hermann R, Derendorf H, von Richter O, Rostami-Hodjegan A. Core Entrustable Professional Activities in Clinical Pharmacology: Pearls for Clinical Practice: Drug-Drug and Food-Drug Interactions. Journal of Clinical Pharmacology. PMID 29513896 DOI: 10.1002/Jcph.1088  0.301
2018 Kempker RR, Heinrichs MT, Nikolaishvili K, Sabulua I, Bablishvili N, Gogishvili S, Avaliani Z, Little BP, Bernheim A, Derendorf H, Blumberg HM, Vashakidze S, Peloquin CA. A comparison of linezolid lung tissue concentrations among patients with drug-resistant tuberculosis. The European Respiratory Journal. 51. PMID 29437945 DOI: 10.1183/13993003.02166-2017  0.301
2018 Sy SKB, Zhuang L, Xia H, Beaudoin ME, Schuck VJ, Nichols WW, Derendorf H. A mathematical model-based analysis of the time-kill kinetics of ceftazidime/avibactam against Pseudomonas aeruginosa. The Journal of Antimicrobial Chemotherapy. PMID 29415212 DOI: 10.1093/Jac/Dkx537  0.763
2018 Deitchman AN, Singh RSP, Rand KH, Derendorf H. Enhanced in vitro tigecycline activity in the presence of chelating agents. International Journal of Antimicrobial Agents. PMID 29305959 DOI: 10.1016/J.Ijantimicag.2017.12.027  0.307
2017 Heinrichs MT, Vashakidze S, Nikolaishvili K, Sabulua I, Tukvadze N, Bablishvili N, Gogishvili S, Little BP, Bernheim A, Guarner J, Peloquin CA, Blumberg HM, Derendorf H, Kempker RR. Moxifloxacin target site concentrations in patients with pulmonary TB utilizing microdialysis: a clinical pharmacokinetic study. The Journal of Antimicrobial Chemotherapy. PMID 29186509 DOI: 10.1093/Jac/Dkx421  0.355
2017 Voelkner NMF, Voelkner A, Costa J, Sy SKB, Hermes J, Weitzel J, Morales S, Derendorf H. Dermal pharmacokinetics of pyrazinamide determined by microdialysis sampling in rats. International Journal of Antimicrobial Agents. PMID 29032112 DOI: 10.1016/J.Ijantimicag.2017.10.001  0.397
2017 Kast J, Yu Y, Seubert CN, Wotring VE, Derendorf H. Drugs in space: Pharmacokinetics and pharmacodynamics in astronauts. European Journal of Pharmaceutical Sciences : Official Journal of the European Federation For Pharmaceutical Sciences. PMID 28533143 DOI: 10.1016/J.Ejps.2017.05.025  0.305
2017 Jadhav SB, Khaowroongrueng V, Fueth M, Otteneder MB, Richter W, Derendorf H. Tissue Distribution of a Therapeutic Monoclonal Antibody Determined by Large Pore Microdialysis. Journal of Pharmaceutical Sciences. PMID 28414146 DOI: 10.1016/J.Xphs.2017.03.033  0.351
2017 Kempker RR, Heinrichs MT, Nikolaishvili K, Sabulua I, Bablishvili N, Gogishvili S, Avaliani Z, Tukvadze N, Little B, Bernheim A, Read TD, Guarner J, Derendorf H, Peloquin CA, Blumberg HM, et al. Lung Tissue Concentrations of Pyrazinamide among Patients with Drug-Resistant Pulmonary Tuberculosis. Antimicrobial Agents and Chemotherapy. PMID 28373198 DOI: 10.1128/Aac.00226-17  0.344
2017 Singh RS, Mukker JK, Drescher SK, Deitchman AN, Derendorf H. A need to revisit clinical breakpoints of tigecycline: effect of atypical non-linear plasma protein binding. International Journal of Antimicrobial Agents. PMID 28237830 DOI: 10.1016/J.Ijantimicag.2016.12.008  0.373
2017 Sy SK, Zhuang L, Beaudoin ME, Kircher P, Tabosa MA, Cavalcanti NC, Grunwitz C, Pieper S, Schuck VJ, Nichols WW, Derendorf H. Potentiation of ceftazidime by avibactam against β-lactam-resistant Pseudomonas aeruginosa in an in vitro infection model. The Journal of Antimicrobial Chemotherapy. PMID 28077672 DOI: 10.1093/Jac/Dkw535  0.741
2016 Deitchman AN, Heinrichs MT, Khaowroongrueng V, Jadhav SB, Derendorf H. Utility of Microdialysis in Infectious Disease Drug Development and Dose Optimization. The Aaps Journal. PMID 27943149 DOI: 10.1208/S12248-016-0020-1  0.376
2016 Deitchman A, de Jong D, Barbour A, Derendorf H. Ceftobiprole medocaril (BAL-5788) for the treatment of complicated skin infections. Expert Review of Anti-Infective Therapy. PMID 27690689 DOI: 10.1080/14787210.2016.1244481  0.704
2016 Mukker JK, Singh RS, Derendorf H. Ciclesonide: A Pro-Soft Drug Approach for Mitigation of Side Effects of Inhaled Corticosteroids. Journal of Pharmaceutical Sciences. PMID 27339407 DOI: 10.1016/J.Xphs.2016.05.004  0.352
2016 Sy SK, Beaudoin ME, Zhuang L, Löblein KI, Lux C, Kissel M, Tremmel R, Frank C, Strasser S, Heuberger JA, Mulder MB, Schuck VJ, Derendorf H. In vitro pharmacokinetics/pharmacodynamics of the combination of avibactam and aztreonam against MDR organisms. The Journal of Antimicrobial Chemotherapy. PMID 27107096 DOI: 10.1093/Jac/Dkw082  0.736
2016 Sy SK, Zhuang L, Derendorf H. Pharmacokinetics and pharmacodynamics in antibiotic dose optimization. Expert Opinion On Drug Metabolism & Toxicology. 12: 93-114. PMID 26652832 DOI: 10.1517/17425255.2016.1123250  0.364
2015 Shilbayeh SA, Sy SK, Melhem M, Zmeili R, Derendorf H. Quantitation of the impact of CYP3A5 A6986G polymorphism on quetiapine pharmacokinetics by simulation of target attainment. Clinical Pharmacology in Drug Development. 4: 387-94. PMID 27137148 DOI: 10.1002/Cpdd.172  0.387
2015 Zhuang L, Xia H, Gu Y, Derendorf H, Li Y, Liu C. Theory and application of microdialysis in pharmacokinetic studies. Current Drug Metabolism. PMID 26264199 DOI: 10.2174/1389200216666150812124109  0.556
2015 Lachi-Silva L, Sy SK, Voelkner A, de Sousa JP, Lopes JL, Silva DB, Lopes NP, Kimura E, Derendorf H, Diniz A. Simultaneous Characterization of Intravenous and Oral Pharmacokinetics of Lychnopholide in Rats by Transit Compartment Model. Planta Medica. 81: 1121-7. PMID 26218336 DOI: 10.1055/S-0035-1546214  0.393
2015 An G, Mukker JK, Derendorf H, Frye RF. Enzyme- and transporter-mediated beverage-drug interactions: An update on fruit juices and green tea. Journal of Clinical Pharmacology. 55: 1313-31. PMID 26095990 DOI: 10.1002/Jcph.563  0.33
2015 Azeredo FJ, Hass SE, Sansone P, Derendorf H, Costa TD, De Araujo BV. Does the Anesthetic Urethane Influence the Pharmacokinetics of Antifungal Drugs? A Population Pharmacokinetic Investigation in Rats. Journal of Pharmaceutical Sciences. 104: 3314-8. PMID 26087701 DOI: 10.1002/Jps.24552  0.4
2015 Buqui GA, Gouvea DR, Sy SK, Voelkner A, Singh RS, da Silva DB, Kimura E, Derendorf H, Lopes NP, Diniz A. Pharmacokinetic evaluation of avicularin using a model-based development approach. Planta Medica. 81: 373-81. PMID 25782034 DOI: 10.1055/S-0035-1545728  0.385
2015 Kempker RR, Barth AB, Vashakidze S, Nikolaishvili K, Sabulua I, Tukvadze N, Bablishvili N, Gogishvili S, Singh RS, Guarner J, Derendorf H, Peloquin CA, Blumberg HM. Cavitary penetration of levofloxacin among patients with multidrug-resistant tuberculosis. Antimicrobial Agents and Chemotherapy. 59: 3149-55. PMID 25779583 DOI: 10.1128/Aac.00379-15  0.348
2015 Mukker JK, Singh RS, Derendorf H. Pharmacokinetic and pharmacodynamic implications in inhalable antimicrobial therapy. Advanced Drug Delivery Reviews. 85: 57-64. PMID 25770775 DOI: 10.1016/J.Addr.2015.03.002  0.365
2015 Sy SK, Malmberg R, Matsushima A, Asin-Prieto E, Rosenkranz B, Cotton MF, Derendorf H, Innes S. Effect of reducing the paediatric stavudine dose by half: a physiologically-based pharmacokinetic model. International Journal of Antimicrobial Agents. 45: 413-9. PMID 25697412 DOI: 10.1016/J.Ijantimicag.2014.12.016  0.351
2015 Wei F, Singh RS, Fueth M, Swarts S, Okunieff P, Derendorf H. Development and validation of a HPLC-MS/MS method for the determination of phytolaccagenin in rat plasma and application to a pharmacokinetic study. Journal of Pharmaceutical and Biomedical Analysis. 107: 82-8. PMID 25575173 DOI: 10.1016/J.Jpba.2014.12.025  0.329
2015 Zhuang L, Sy SK, Xia H, Singh RP, Mulder MB, Liu C, Derendorf H. Evaluation of in vitro synergy between vertilmicin and ceftazidime against Pseudomonas aeruginosa using a semi-mechanistic pharmacokinetic/pharmacodynamic model. International Journal of Antimicrobial Agents. 45: 151-60. PMID 25465523 DOI: 10.1016/J.Ijantimicag.2014.09.017  0.425
2015 Scheerans C, Wicha SG, Michael J, Derendorf H, Kloft C. Concentration-response studies and modelling of the pharmacodynamics of linezolid: Staphylococcus aureus versus Enterococcus faecium. International Journal of Antimicrobial Agents. 45: 54-60. PMID 25455852 DOI: 10.1016/J.Ijantimicag.2014.07.028  0.422
2015 Buqui GA, Sy SK, Merino-Sanjuán M, Gouvea DR, Nixdorf SL, Kimura E, Derendorf H, Lopes NP, Diniz A. Characterization of intestinal absorption of C -glycoside flavonoid vicenin-2 from Lychnophora ericoides leafs in rats by nonlinear mixed effects modeling Revista Brasileira De Farmacognosia. 25: 212-218. DOI: 10.1016/J.Bjp.2015.04.001  0.325
2014 K Hurtado F, Laureano JV, de A Lock G, Derendorf H, Dalla Costa T. Enhanced penetration of moxifloxacin into rat prostate tissue evidenced by microdialysis. International Journal of Antimicrobial Agents. 44: 327-33. PMID 25218157 DOI: 10.1016/J.Ijantimicag.2014.06.011  0.328
2014 Deitchman AN, Derendorf H. Measuring drug distribution in the critically ill patient. Advanced Drug Delivery Reviews. 77: 22-6. PMID 25194997 DOI: 10.1016/J.Addr.2014.08.014  0.333
2014 de Kock L, Sy SK, Rosenkranz B, Diacon AH, Prescott K, Hernandez KR, Yu M, Derendorf H, Donald PR. Pharmacokinetics of para-aminosalicylic acid in HIV-uninfected and HIV-coinfected tuberculosis patients receiving antiretroviral therapy, managed for multidrug-resistant and extensively drug-resistant tuberculosis. Antimicrobial Agents and Chemotherapy. 58: 6242-50. PMID 25114132 DOI: 10.1128/Aac.03073-14  0.338
2014 Zühlsdorf M, Bhattaram VA, Campioni M, Krösser S, Derendorf H, Kovar A. Population pharmacokinetics of cilengitide in adult and pediatric cancer patients from a nonlinear mixed-effects analysis. Journal of Clinical Pharmacology. 54: 1391-9. PMID 24911832 DOI: 10.1002/Jcph.343  0.343
2014 Egelund EF, Weiner M, Singh RP, Prihoda TJ, Gelfond JA, Derendorf H, Mac Kenzie WR, Peloquin CA. Protein binding of rifapentine and its 25-desacetyl metabolite in patients with pulmonary tuberculosis. Antimicrobial Agents and Chemotherapy. 58: 4904-10. PMID 24841270 DOI: 10.1128/Aac.01730-13  0.326
2014 Ikawa K, Kikuchi E, Kikuchi J, Nishimura M, Derendorf H, Morikawa N. Pharmacokinetic modelling of serum and bronchial concentrations for clarithromycin and telithromycin, and site-specific pharmacodynamic simulation for their dosages. Journal of Clinical Pharmacy and Therapeutics. 39: 411-7. PMID 24661290 DOI: 10.1111/Jcpt.12157  0.319
2014 Yu M, Salvador LA, Sy SK, Tang Y, Singh RS, Chen QY, Liu Y, Hong J, Derendorf H, Luesch H. Largazole pharmacokinetics in rats by LC-MS/MS. Marine Drugs. 12: 1623-40. PMID 24658499 DOI: 10.3390/Md12031623  0.313
2014 Azeredo FJ, Dalla Costa T, Derendorf H. Role of microdialysis in pharmacokinetics and pharmacodynamics: current status and future directions. Clinical Pharmacokinetics. 53: 205-12. PMID 24452811 DOI: 10.1007/S40262-014-0131-8  0.379
2014 Sy SK, Innes S, Derendorf H, Cotton MF, Rosenkranz B. Estimation of intracellular concentration of stavudine triphosphate in HIV-infected children given a reduced dose of 0.5 milligrams per kilogram twice daily. Antimicrobial Agents and Chemotherapy. 58: 1084-91. PMID 24295968 DOI: 10.1128/Aac.01717-13  0.35
2014 Hurtado FK, Weber B, Derendorf H, Hochhaus G, Dalla Costa T. Population pharmacokinetic modeling of the unbound levofloxacin concentrations in rat plasma and prostate tissue measured by microdialysis. Antimicrobial Agents and Chemotherapy. 58: 678-86. PMID 24217697 DOI: 10.1128/Aac.01884-13  0.318
2014 Barbour AM, Schmidt S, Zhuang L, Rand K, Derendorf H. Application of pharmacokinetic/pharmacodynamic modelling and simulation for the prediction of target attainment of ceftobiprole against meticillin-resistant Staphylococcus aureus using minimum inhibitory concentration and time-kill curve based approaches. International Journal of Antimicrobial Agents. 43: 60-7. PMID 24183800 DOI: 10.1016/J.Ijantimicag.2013.08.016  0.754
2014 Folzer E, Gonzalez D, Singh R, Derendorf H. Comparison of skin permeability for three diclofenac topical formulations: an in vitro study. Die Pharmazie. 69: 27-31. DOI: 10.1691/Ph.2014.3087  0.34
2013 Derendorf H, Drehsen G, Rohdewald P. Antipyrine - new light on an old drug. Pharmaceutical Research. 1: 225-9. PMID 24277333 DOI: 10.1023/A:1016325414419  0.387
2013 Sy SK, Heuberger J, Shilbayeh S, Conrado DJ, Derendorf H. A Markov chain model to evaluate the effect of CYP3A5 and ABCB1 polymorphisms on adverse events associated with tacrolimus in pediatric renal transplantation. The Aaps Journal. 15: 1189-99. PMID 23990505 DOI: 10.1208/S12248-013-9528-9  0.307
2013 Ibarra M, Vázquez M, Fagiolino P, Derendorf H. Sex related differences on valproic acid pharmacokinetics after oral single dose. Journal of Pharmacokinetics and Pharmacodynamics. 40: 479-86. PMID 23784346 DOI: 10.1007/S10928-013-9323-3  0.357
2013 Li L, Han AR, Kinghorn AD, Frye RF, Derendorf H, Butterweck V. Pharmacokinetic properties of pure xanthones in comparison to a mangosteen fruit extract in rats. Planta Medica. 79: 646-53. PMID 23673465 DOI: 10.1055/S-0032-1328543  0.319
2013 Gonzalez D, Schmidt S, Derendorf H. Importance of relating efficacy measures to unbound drug concentrations for anti-infective agents. Clinical Microbiology Reviews. 26: 274-88. PMID 23554417 DOI: 10.1128/Cmr.00092-12  0.431
2013 Desoky ESE, Ghazal MH, Singh RP, Abdelhamid ON, Derendorf H. Population Pharmacokinetics of Methotrexate in Egyptian Children with Lymphoblastic Leukemia Pharmacology &Amp; Pharmacy. 4: 139-145. DOI: 10.4236/Pp.2013.42020  0.367
2012 Chooluck K, Singh RP, Sathirakul K, Derendorf H. Dermal pharmacokinetics of Terpinen-4-ol following topical administration of Zingiber cassumunar (plai) oil. Planta Medica. 78: 1761-6. PMID 23027380 DOI: 10.1055/S-0032-1315262  0.32
2012 Butterweck V, Derendorf H. Herb-drug interactions. Planta Medica. 78: 1399. PMID 22951920 DOI: 10.1055/S-0032-1315285  0.324
2012 Sahre M, Sabarinath S, Grant M, Seubert C, Deanda C, Prokocimer P, Derendorf H. Skin and soft tissue concentrations of tedizolid (formerly torezolid), a novel oxazolidinone, following a single oral dose in healthy volunteers. International Journal of Antimicrobial Agents. 40: 51-4. PMID 22584101 DOI: 10.1016/J.Ijantimicag.2012.03.006  0.359
2012 Sampath C, Haug K, Thanei S, Hamburger M, Derendorf H, Frye R, Butterweck V. Pharmacokinetics of valerenic acid in rats after intravenous and oral administrations. Planta Medica. 78: 575-81. PMID 22411722 DOI: 10.1055/S-0031-1298301  0.377
2012 Derendorf H, Munzel U, Petzold U, Maus J, Mascher H, Hermann R, Bousquet J. Bioavailability and disposition of azelastine and fluticasone propionate when delivered by MP29-02, a novel aqueous nasal spray. British Journal of Clinical Pharmacology. 74: 125-33. PMID 22356350 DOI: 10.1111/J.1365-2125.2012.04222.X  0.336
2011 Ikawa K, Nakashima A, Morikawa N, Ikeda K, Murakami Y, Ohge H, Derendorf H, Sueda T. Clinical pharmacokinetics of meropenem and biapenem in bile and dosing considerations for biliary tract infections based on site-specific pharmacodynamic target attainment. Antimicrobial Agents and Chemotherapy. 55: 5609-15. PMID 21947393 DOI: 10.1128/Aac.00497-11  0.379
2011 Ardjomand-Woelkart K, Kollroser M, Magnes C, Sinner F, Frye RF, Derendorf H, Bauer R, Butterweck V. Absolute/relative bioavailability and metabolism of dodeca-2E,4E,8Z,10E/Z-tetraenoic acid isobutylamides (tetraenes) after intravenous and oral single doses to rats. Planta Medica. 77: 1794-9. PMID 21604240 DOI: 10.1055/S-0030-1271120  0.31
2011 Gonzalez D, Conrado DJ, Theuretzbacher U, Derendorf H. The effect of critical illness on drug distribution. Current Pharmaceutical Biotechnology. 12: 2030-6. PMID 21554214 DOI: 10.2174/138920111798808211  0.351
2011 Reddy P, Ellington D, Zhu Y, Zdrojewski I, Parent SJ, Harmatz JS, Derendorf H, Greenblatt DJ, Browne K. Serum concentrations and clinical effects of atorvastatin in patients taking grapefruit juice daily. British Journal of Clinical Pharmacology. 72: 434-41. PMID 21501216 DOI: 10.1111/J.1365-2125.2011.03996.X  0.339
2011 Wu BM, Sabarinath SN, Rand K, Johnson J, Derendorf H. Suppression of ciprofloxacin-induced resistant Pseudomonas aeruginosa in a dynamic kill curve system. International Journal of Antimicrobial Agents. 37: 519-24. PMID 21497064 DOI: 10.1016/J.Ijantimicag.2011.01.021  0.399
2011 O'Connor D, Adams WP, Chen ML, Daley-Yates P, Davis J, Derendorf H, Ducharme MP, Fuglsang A, Herrle M, Hochhaus G, Holmes SM, Lee SL, Li BV, Lyapustina S, Newman S, et al. Role of pharmacokinetics in establishing bioequivalence for orally inhaled drug products: workshop summary report. Journal of Aerosol Medicine and Pulmonary Drug Delivery. 24: 119-35. PMID 21453049 DOI: 10.1089/Jamp.2011.0878  0.38
2011 Singh RP, Derendorf H, Ross EA. Simulation-based sodium thiosulfate dosing strategies for the treatment of calciphylaxis. Clinical Journal of the American Society of Nephrology : Cjasn. 6: 1155-9. PMID 21441129 DOI: 10.2215/Cjn.09671010  0.38
2011 Sabarinath SN, Wu B, Peloquin C, Derendorf H. Pharmacometrics in dose finding or dose optimization of anti-retroviral and anti-tubercular drugs. Infectious Disorders Drug Targets. 11: 157-66. PMID 21406049 DOI: 10.2174/187152611795589681  0.377
2011 Kumar V, Madabushi R, Lucchesi MB, Derendorf H. Pharmacokinetics of cefpodoxime in plasma and subcutaneous fluid following oral administration of cefpodoxime proxetil in male beagle dogs. Journal of Veterinary Pharmacology and Therapeutics. 34: 130-5. PMID 21395603 DOI: 10.1111/J.1365-2885.2010.01198.X  0.377
2011 Ardjomand-Woelkart K, Kollroser M, Li L, Derendorf H, Butterweck V, Bauer R. Development and validation of a LC-MS/MS method based on a new 96-well Hybrid-SPE™-precipitation technique for quantification of CYP450 substrates/metabolites in rat plasma. Analytical and Bioanalytical Chemistry. 400: 2371-81. PMID 21225250 DOI: 10.1055/S-0030-1264855  0.321
2011 Potocka E, Baughman RA, Derendorf H. Population pharmacokinetic model of human insulin following different routes of administration. Journal of Clinical Pharmacology. 51: 1015-24. PMID 20940337 DOI: 10.1177/0091270010378520  0.762
2011 Ahmad Z, Peloquin CA, Singh RP, Derendorf H, Tyagi S, Ginsberg A, Grosset JH, Nuermberger EL. PA-824 exhibits time-dependent activity in a murine model of tuberculosis. Antimicrobial Agents and Chemotherapy. 55: 239-45. PMID 20937781 DOI: 10.1128/Aac.00849-10  0.406
2010 Shi R, Derendorf H. Pediatric Dosing and Body Size in Biotherapeutics. Pharmaceutics. 2: 389-418. PMID 27721364 DOI: 10.3390/Pharmaceutics2040389  0.332
2010 Estes KS, Derendorf H. Comparison of the pharmacokinetic properties of vancomycin, linezolid, tigecyclin, and daptomycin. European Journal of Medical Research. 15: 533-43. PMID 21163728 DOI: 10.1186/2047-783X-15-12-533  0.404
2010 Barbour A, Derendorf H. Resistance and the management of complicated skin and skin structure infections: the role of ceftobiprole. Therapeutics and Clinical Risk Management. 6: 485-95. PMID 20957140 DOI: 10.2147/Tcrm.S5823  0.715
2010 Conrado DJ, Gonzalez D, Derendorf H. Role of drug absorption in the pharmacokinetics of therapeutic interventions for stroke. Annals of the New York Academy of Sciences. 1207: 134-42. PMID 20955436 DOI: 10.1111/J.1749-6632.2010.05729.X  0.333
2010 Vieira Mde L, Singh RP, Derendorf H. Simultaneous HPLC analysis of triamcinolone acetonide and budesonide in microdialysate and rat plasma: application to a pharmacokinetic study. Journal of Chromatography. B, Analytical Technologies in the Biomedical and Life Sciences. 878: 2967-73. PMID 20884303 DOI: 10.1016/J.Jchromb.2010.08.048  0.323
2010 Morey TE, Modell JH, Garcia JE, Bewernitz M, Derendorf H, Varshney M, Gravenstein N, Shah DO, Dennis DM. Thromboelastographic and pharmacokinetic profiles of micro- and macro-emulsions of propofol in swine. Biopharmaceutics & Drug Disposition. 31: 269-77. PMID 20578214 DOI: 10.1002/Bdd.709  0.342
2010 Li Y, Theuretzbacher U, Clancy CJ, Nguyen MH, Derendorf H. Pharmacokinetic/pharmacodynamic profile of posaconazole. Clinical Pharmacokinetics. 49: 379-96. PMID 20481649 DOI: 10.2165/11319340-000000000-00000  0.582
2010 Barbour A, Scaglione F, Derendorf H. Class-dependent relevance of tissue distribution in the interpretation of anti-infective pharmacokinetic/pharmacodynamic indices. International Journal of Antimicrobial Agents. 35: 431-8. PMID 20219329 DOI: 10.1016/J.Ijantimicag.2010.01.023  0.753
2010 Xu J, Nave R, Lahu G, Derom E, Derendorf H. Population pharmacokinetics and pharmacodynamics of inhaled ciclesonide and fluticasone propionate in patients with persistent asthma. Journal of Clinical Pharmacology. 50: 1118-27. PMID 20150524 DOI: 10.1177/0091270009354994  0.334
2010 Ghobrial O, Derendorf H, Hillman JD. Pharmacokinetic and pharmacodynamic evaluation of the lantibiotic MU1140. Journal of Pharmaceutical Sciences. 99: 2521-8. PMID 20039385 DOI: 10.1002/Jps.22015  0.399
2010 Gloede J, Scheerans C, Derendorf H, Kloft C. In vitro pharmacodynamic models to determine the effect of antibacterial drugs. The Journal of Antimicrobial Chemotherapy. 65: 186-201. PMID 20026612 DOI: 10.1093/Jac/Dkp434  0.401
2010 Schmidt S, Gonzalez D, Derendorf H. Significance of protein binding in pharmacokinetics and pharmacodynamics. Journal of Pharmaceutical Sciences. 99: 1107-22. PMID 19852037 DOI: 10.1002/Jps.21916  0.307
2009 Schmidt S, Sabarinath SN, Barbour A, Abbanat D, Manitpisitkul P, Sha S, Derendorf H. Pharmacokinetic-pharmacodynamic modeling of the in vitro activities of oxazolidinone antimicrobial agents against methicillin-resistant Staphylococcus aureus. Antimicrobial Agents and Chemotherapy. 53: 5039-45. PMID 19786607 DOI: 10.1128/Aac.00633-09  0.753
2009 Barbour A, Schmidt S, Ma B, Schiefelbein L, Rand KH, Burkhardt O, Derendorf H. Clinical pharmacokinetics and pharmacodynamics of tigecycline. Clinical Pharmacokinetics. 48: 575-84. PMID 19725592 DOI: 10.2165/11317100-000000000-00000  0.738
2009 Barbour A, Schmidt S, Rout WR, Ben-David K, Burkhardt O, Derendorf H. Soft tissue penetration of cefuroxime determined by clinical microdialysis in morbidly obese patients undergoing abdominal surgery. International Journal of Antimicrobial Agents. 34: 231-5. PMID 19411164 DOI: 10.1016/J.Ijantimicag.2009.03.019  0.713
2009 Woelkart K, Frye RF, Derendorf H, Bauer R, Butterweck V. Pharmacokinetics and tissue distribution of dodeca-2E,4E,8E,10E/Z-tetraenoic acid isobutylamides after oral administration in rats. Planta Medica. 75: 1306-13. PMID 19399718 DOI: 10.1055/S-0029-1185631  0.323
2009 Barbour A, Schmidt S, Sabarinath SN, Grant M, Seubert C, Skee D, Murthy B, Derendorf H. Soft-tissue penetration of ceftobiprole in healthy volunteers determined by in vivo microdialysis. Antimicrobial Agents and Chemotherapy. 53: 2773-6. PMID 19364847 DOI: 10.1128/Aac.01409-08  0.74
2009 Butterweck V, Zdrojewski I, Galloway C, Frye R, Derendorf H. Toxicological and Pharmacokinetic Evaluation of Concomitant Intake of Grapefruit Juice and Simvastatin in Rats after Repeated Treatment over 28 Days. Planta Medica. 75: 1196-202. PMID 19350484 DOI: 10.1055/S-0029-1185534  0.345
2009 Li Y, Nguyen MH, Schmidt S, Zhong L, Derendorf H, Clancy CJ. Pharmacokinetic/pharmacodynamic modelling and in vitro simulation of dynamic voriconazole-Candida interactions. International Journal of Antimicrobial Agents. 34: 240-5. PMID 19339162 DOI: 10.1016/J.Ijantimicag.2009.02.006  0.514
2009 Ghobrial OG, Derendorf H, Hillman JD. Development and validation of a LC-MS quantification method for the lantibiotic MU1140 in rat plasma. Journal of Pharmaceutical and Biomedical Analysis. 49: 970-5. PMID 19269770 DOI: 10.1016/J.Jpba.2008.12.022  0.316
2009 Barbour A, Schmidt S, Rand KH, Derendorf H. Ceftobiprole: a novel cephalosporin with activity against Gram-positive and Gram-negative pathogens, including methicillin-resistant Staphylococcus aureus (MRSA). International Journal of Antimicrobial Agents. 34: 1-7. PMID 19261449 DOI: 10.1016/J.Ijantimicag.2008.12.012  0.728
2009 Ghobrial OG, Derendorf H, Hillman JD. Pharmacodynamic activity of the lantibiotic MU1140. International Journal of Antimicrobial Agents. 33: 70-4. PMID 18835136 DOI: 10.1016/J.Ijantimicag.2008.07.028  0.305
2009 Gonzalez D, Derendorf H. Ciclesonide in the Management of Asthma Clinical Medicine. Therapeutics. 1: CMT.S2133. DOI: 10.4137/Cmt.S2133  0.341
2009 Zuehlsdorf M, Bhattaram VA, Kroesser S, Derendorf H, Kovar A. Abstract B214: Use of a pharmacokinetic model derived from early clinical studies to assess the relevance of covariates on cilengitide pharmacokinetics Molecular Cancer Therapeutics. 8. DOI: 10.1158/1535-7163.Targ-09-B214  0.338
2008 Derendorf H, Meltzer EO. Molecular and clinical pharmacology of intranasal corticosteroids: Clinical and therapeutic implications Allergy: European Journal of Allergy and Clinical Immunology. 63: 1292-1300. PMID 18782107 DOI: 10.1111/J.1398-9995.2008.01750.X  0.318
2008 Schmidt S, Röck K, Sahre M, Burkhardt O, Brunner M, Lobmeyer MT, Derendorf H. Effect of protein binding on the pharmacological activity of highly bound antibiotics. Antimicrobial Agents and Chemotherapy. 52: 3994-4000. PMID 18779351 DOI: 10.1128/Aac.00427-08  0.348
2008 Mertens-Talcott SU, Rios J, Jilma-Stohlawetz P, Pacheco-Palencia LA, Meibohm B, Talcott ST, Derendorf H. Pharmacokinetics of anthocyanins and antioxidant effects after the consumption of anthocyanin-rich acai juice and pulp (Euterpe oleracea Mart.) in human healthy volunteers. Journal of Agricultural and Food Chemistry. 56: 7796-802. PMID 18693743 DOI: 10.1021/Jf8007037  0.365
2008 Liu J, Pan H, Gold MS, Derendorf H, Bruijnzeel AW. Effects of fentanyl dose and exposure duration on the affective and somatic signs of fentanyl withdrawal in rats. Neuropharmacology. 55: 812-8. PMID 18634811 DOI: 10.1016/J.Neuropharm.2008.06.034  0.3
2008 Schmidt S, Barbour A, Sahre M, Rand KH, Derendorf H. PK/PD: new insights for antibacterial and antiviral applications. Current Opinion in Pharmacology. 8: 549-56. PMID 18625339 DOI: 10.1016/J.Coph.2008.06.010  0.719
2008 Xu J, Winkler J, Sabarinath SN, Derendorf H. Assessment of the impact of dosing time on the pharmacokinetics/pharmacodynamics of prednisolone. The Aaps Journal. 10: 331-41. PMID 18581240 DOI: 10.1208/S12248-008-9038-3  0.418
2008 Butterweck V, Derendorf H. Potential of pharmacokinetic profiling for detecting herbal interactions with drugs. Clinical Pharmacokinetics. 47: 383-97. PMID 18479173 DOI: 10.2165/00003088-200847060-00003  0.332
2008 Schmidt S, Banks R, Kumar V, Rand KH, Derendorf H. Clinical microdialysis in skin and soft tissues: an update. Journal of Clinical Pharmacology. 48: 351-64. PMID 18285620 DOI: 10.1177/0091270007312152  0.392
2008 Li Y, Nguyen MH, Cheng S, Schmidt S, Zhong L, Derendorf H, Clancy CJ. A pharmacokinetic/pharmacodynamic mathematical model accurately describes the activity of voriconazole against Candida spp. in vitro. International Journal of Antimicrobial Agents. 31: 369-74. PMID 18215509 DOI: 10.1016/J.Ijantimicag.2007.11.015  0.524
2008 Scheerans C, Derendorf H, Kloft C. Proposal for a standardised identification of the mono-exponential terminal phase for orally administered drugs. Biopharmaceutics & Drug Disposition. 29: 145-57. PMID 18098336 DOI: 10.1002/Bdd.596  0.375
2008 Mouton JW, Theuretzbacher U, Craig WA, Tulkens PM, Derendorf H, Cars O. Tissue concentrations: do we ever learn? The Journal of Antimicrobial Chemotherapy. 61: 235-7. PMID 18065413 DOI: 10.1093/Jac/Dkm476  0.372
2007 Schmidt S, Schuck E, Kumar V, Burkhardt O, Derendorf H. Integration of pharmacokinetic/pharmacodynamic modeling and simulation in the development of new anti-infective agents - minimum inhibitory concentration versus time-kill curves. Expert Opinion On Drug Discovery. 2: 849-60. PMID 23489002 DOI: 10.1517/17460441.2.6.849  0.737
2007 Li Y, Nguyen MH, Derendorf H, Cheng S, Clancy CJ. Measurement of voriconazole activity against Candida albicans, C. glabrata, and C. parapsilosis isolates using time-kill methods validated by high-performance liquid chromatography. Antimicrobial Agents and Chemotherapy. 51: 2985-7. PMID 17517840 DOI: 10.1128/Aac.00308-07  0.477
2007 Chaurasia CS, Müller M, Bashaw ED, Benfeldt E, Bolinder J, Bullock R, Bungay PM, DeLange EC, Derendorf H, Elmquist WF, Hammarlund-Udenaes M, Joukhadar C, Kellogg DL, Lunte CE, Nordstrom CH, et al. AAPS-FDA Workshop White Paper: microdialysis principles, application, and regulatory perspectives. Journal of Clinical Pharmacology. 47: 589-603. PMID 17442685 DOI: 10.1177/0091270006299091  0.348
2007 Vogt M, Derendorf H, Krämer J, Junginger HE, Midha KK, Shah VP, Stavchansky S, Dressman JB, Barends DM. Biowaiver monographs for immediate release solid oral dosage forms: prednisone. Journal of Pharmaceutical Sciences. 96: 1480-9. PMID 17387693 DOI: 10.1002/Jps.20817  0.312
2007 Xu J, Winkler J, Derendorf H. A pharmacokinetic/pharmacodynamic approach to predict total prednisolone concentrations in human plasma. Journal of Pharmacokinetics and Pharmacodynamics. 34: 355-72. PMID 17318442 DOI: 10.1007/S10928-007-9050-8  0.363
2007 Burkhardt O, Derendorf H, Welte T. Ertapenem: the new carbapenem 5 years after first FDA licensing for clinical practice. Expert Opinion On Pharmacotherapy. 8: 237-56. PMID 17257093 DOI: 10.1517/14656566.8.2.237  0.381
2007 Burkhardt O, Kumar V, Katterwe D, Majcher-Peszynska J, Drewelow B, Derendorf H, Welte T. Ertapenem in critically ill patients with early-onset ventilator-associated pneumonia: pharmacokinetics with special consideration of free-drug concentration. The Journal of Antimicrobial Chemotherapy. 59: 277-84. PMID 17185298 DOI: 10.1093/Jac/Dkl485  0.388
2007 Vogt M, Derendorf H, Krämer J, Junginger HE, Midha KK, Shah VP, Stavchansky S, Dressman JB, Barends DM. Biowaiver monographs for immediate release solid oral dosage forms: prednisolone. Journal of Pharmaceutical Sciences. 96: 27-37. PMID 17039494 DOI: 10.1002/Jps.20768  0.319
2007 Butterweck V, Zdrojewski I, De Castro W, Derendorf H. Exploring mechanisms of grapefruit juice drug interactions and its potential toxicity Planta Medica. 73. DOI: 10.1055/S-2007-986716  0.302
2006 El Desoky ES, Derendorf H, Klotz U. Variability in response to cardiovascular drugs. Current Clinical Pharmacology. 1: 35-46. PMID 18666376 DOI: 10.2174/157488406775268273  0.342
2006 Treyaprasert W, Schmidt S, Rand KH, Suvanakoot U, Derendorf H. Pharmacokinetic/pharmacodynamic modeling of in vitro activity of azithromycin against four different bacterial strains. International Journal of Antimicrobial Agents. 29: 263-70. PMID 17194570 DOI: 10.1016/J.Ijantimicag.2006.08.049  0.356
2006 Mertens-Talcott SU, Zadezensky I, De Castro WV, Derendorf H, Butterweck V. Grapefruit-drug interactions: can interactions with drugs be avoided? Journal of Clinical Pharmacology. 46: 1390-416. PMID 17101740 DOI: 10.1177/0091270006294277  0.301
2006 Meltzer EO, Derendorf H. The systemic safety of inhaled corticosteroid therapy: A focus on ciclesonide Annals of Allergy, Asthma and Immunology. 97: 149-157. PMID 16937743 DOI: 10.1016/S1081-1206(10)60005-1  0.331
2006 Burkhardt O, Lehmann C, Madabushi R, Kumar V, Derendorf H, Welte T. Once-daily tobramycin in cystic fibrosis: better for clinical outcome than thrice-daily tobramycin but more resistance development? The Journal of Antimicrobial Chemotherapy. 58: 822-9. PMID 16885180 DOI: 10.1093/Jac/Dkl328  0.336
2006 Theuretzbacher U, Ihle F, Derendorf H. Pharmacokinetic/pharmacodynamic profile of voriconazole. Clinical Pharmacokinetics. 45: 649-63. PMID 16802848 DOI: 10.2165/00003088-200645070-00002  0.348
2006 Li Y, Peris J, Zhong L, Derendorf H. Microdialysis as a tool in local pharmacodynamics. The Aaps Journal. 8: E222-35. PMID 16796373 DOI: 10.1007/Bf02854892  0.524
2006 Madabushi R, Frank B, Drewelow B, Derendorf H, Butterweck V. Hyperforin in St. John's wort drug interactions. European Journal of Clinical Pharmacology. 62: 225-33. PMID 16477470 DOI: 10.1007/S00228-006-0096-0  0.342
2006 De Castro WV, Mertens-Talcott S, Rubner A, Butterweck V, Derendorf H. Variation of flavonoids and furanocoumarins in grapefruit juices: a potential source of variability in grapefruit juice-drug interaction studies. Journal of Agricultural and Food Chemistry. 54: 249-55. PMID 16390207 DOI: 10.1021/Jf0516944  0.337
2006 Brunner M, Derendorf H, Müller M. Microdialysis for in vivo pharmacokinetic/pharmacodynamic characterization of anti-infective drugs. Current Opinion in Pharmacology. 5: 495-9. PMID 16084767 DOI: 10.1016/J.Coph.2005.04.010  0.38
2006 el-Desoky ES, Madabushi R, Amry Sel-D, Bhattaram VA, Derendorf H. Application of two-point assay of digoxin serum concentration in studying population pharmacokinetics in Egyptian pediatric patients with heart failure: does it make sense? American Journal of Therapeutics. 12: 320-7. PMID 16041195 DOI: 10.1097/01.Mjt.0000155108.62208.82  0.356
2006 Burkhardt O, Majcher-Peszynska J, Borner K, Mundkowski R, Drewelow B, Derendorf H, Welte T. Penetration of ertapenem into different pulmonary compartments of patients undergoing lung surgery. Journal of Clinical Pharmacology. 45: 659-65. PMID 15901747 DOI: 10.1177/0091270005276117  0.344
2006 Bhattaram VA, Nagaraja NV, Peters T, Machnig T, Kroesser S, Kovar A, Derendorf H. Population pharmacokinetics of eniporide and its metabolite in healthy subjects and patients with acute myocardial infarction. Journal of Clinical Pharmacology. 45: 631-9. PMID 15901744 DOI: 10.1177/0091270004274431  0.322
2006 BRUNNER M, DERENDORF H. Clinical microdialysis: Current applications and potential use in drug development Trac Trends in Analytical Chemistry. 25: 674-680. DOI: 10.1016/J.Trac.2006.05.004  0.345
2006 Meibohm B, Derendorf H. Pharmacokinetics and Pharmacodynamics of Biotech Drugs Reviews in Cell Biology and Molecular Medicine. 145-172. DOI: 10.1002/3527600906.Mcb.200400105  0.383
2005 Schuck EL, Dalhoff A, Stass H, Derendorf H. Pharmacokinetic/pharmacodynamic (PK/PD) evaluation of a once-daily treatment using ciprofloxacin in an extended-release dosage form. Infection. 33: 22-8. PMID 16518708 DOI: 10.1007/s15010-005-8204-0  0.691
2005 Hübner M, Hochhaus G, Derendorf H. Comparative pharmacology, bioavailability, pharmacokinetics, and pharmacodynamics of inhaled glucocorticosteroids Immunology and Allergy Clinics of North America. 25: 469-488. PMID 16054538 DOI: 10.1016/J.Iac.2005.05.004  0.338
2005 Schuck EL, Derendorf H. Pharmacokinetic/pharmacodynamic evaluation of anti-infective agents. Expert Review of Anti-Infective Therapy. 3: 361-73. PMID 15954853 DOI: 10.1586/14787210.3.3.361  0.725
2005 Schuck EL, Grant M, Derendorf H. Effect of simulated microgravity on the disposition and tissue penetration of ciprofloxacin in healthy volunteers. Journal of Clinical Pharmacology. 45: 822-31. PMID 15951472 DOI: 10.1177/0091270005276620  0.724
2005 Liu P, Müller M, Grant M, Obermann B, Derendorf H. Tissue penetration of cefpodoxime and cefixime in healthy subjects. Journal of Clinical Pharmacology. 45: 564-9. PMID 15831780 DOI: 10.1177/0091270004273679  0.388
2005 Krishnaswami S, Hochhaus G, Möllmann H, Barth J, Derendorf H. Interpretation of absorption rate data for inhaled fluticasone propionate obtained in compartmental pharmacokinetic modeling. International Journal of Clinical Pharmacology and Therapeutics. 43: 117-22. PMID 15792395  0.634
2005 Mouton JW, Dudley MN, Cars O, Derendorf H, Drusano GL. Standardization of pharmacokinetic/pharmacodynamic (PK/PD) terminology for anti-infective drugs: an update. The Journal of Antimicrobial Chemotherapy. 55: 601-7. PMID 15772142 DOI: 10.1093/Jac/Dki079  0.329
2005 Wittemer SM, Ploch M, Windeck T, Müller SC, Drewelow B, Derendorf H, Veit M. Bioavailability and pharmacokinetics of caffeoylquinic acids and flavonoids after oral administration of Artichoke leaf extracts in humans. Phytomedicine : International Journal of Phytotherapy and Phytopharmacology. 12: 28-38. PMID 15693705 DOI: 10.1016/J.Phymed.2003.11.002  0.322
2005 Liu P, Rand KH, Obermann B, Derendorf H. Pharmacokinetic-pharmacodynamic modelling of antibacterial activity of cefpodoxime and cefixime in in vitro kinetic models. International Journal of Antimicrobial Agents. 25: 120-9. PMID 15664481 DOI: 10.1016/J.Ijantimicag.2004.09.012  0.39
2005 Buck C, Bertram N, Ackermann T, Sauerbruch T, Derendorf H, Paar WD. Pharmacokinetics of piperacillin-tazobactam: intermittent dosing versus continuous infusion. International Journal of Antimicrobial Agents. 25: 62-7. PMID 15620828 DOI: 10.1016/J.Ijantimicag.2004.08.012  0.4
2005 Kim K, Johnson JA, Derendorf H. Differences in drug pharmacokinetics between East Asians and Caucasians and the role of genetic polymorphisms. Journal of Clinical Pharmacology. 44: 1083-105. PMID 15342610 DOI: 10.1177/0091270004268128  0.34
2005 Yanong RPE, Curtis EW, Simmons R, Bhattaram VA, Gopalakrishnan M, Ketabi N, Nagaraja NV, Derendorf H. Pharmacokinetic Studies of Florfenicol in Koi Carp and Threespot GouramiTrichogaster trichopterusafter Oral and Intramuscular Treatment Journal of Aquatic Animal Health. 17: 129-137. DOI: 10.1577/H03-065.1  0.383
2004 Schuck VJ, Rinas I, Derendorf H. In vitro microdialysis sampling of docetaxel. Journal of Pharmaceutical and Biomedical Analysis. 36: 807-13. PMID 15533674 DOI: 10.1016/J.Jpba.2004.07.007  0.737
2004 Butterweck V, Derendorf H, Gaus W, Nahrstedt A, Schulz V, Unger M. Pharmacokinetic herb-drug interactions: are preventive screenings necessary and appropriate? Planta Medica. 70: 784-91. PMID 15386186 DOI: 10.1055/S-2004-827223  0.329
2004 Graebe A, Schuck EL, Lensing P, Putcha L, Derendorf H. Physiological, pharmacokinetic, and pharmacodynamic changes in space. Journal of Clinical Pharmacology. 44: 837-53. PMID 15286087 DOI: 10.1177/0091270004267193  0.693
2004 de la Peña A, Gräbe A, Rand KH, Rehak E, Gross J, Thyroff-Friesinger U, Müller M, Derendorf H. PK-PD modelling of the effect of cefaclor on four different bacterial strains. International Journal of Antimicrobial Agents. 23: 218-25. PMID 15164961 DOI: 10.1016/J.Ijantimicag.2003.07.009  0.764
2004 Liu Q, Rand K, Derendorf H. Impact of tazobactam pharmacokinetics on the antimicrobial effect of piperacillin-tazobactam combinations. International Journal of Antimicrobial Agents. 23: 494-7. PMID 15120729 DOI: 10.1016/J.Ijantimicag.2003.10.012  0.357
2004 Müller M, dela Peña A, Derendorf H. Issues in pharmacokinetics and pharmacodynamics of anti-infective agents: distribution in tissue. Antimicrobial Agents and Chemotherapy. 48: 1441-53. PMID 15105091 DOI: 10.1128/Aac.48.5.1441-1453.2004  0.361
2004 Hermann R, Locher M, Siebert-Weigel M, LaVallee N, Derendorf H, Hochhaus G. Intranasal loteprednol etabonate in healthy male subjects: pharmacokinetics and effects on endogenous cortisol. Journal of Clinical Pharmacology. 44: 510-9. PMID 15102872 DOI: 10.1177/0091270004264163  0.365
2004 Mueller M, de la Peña A, Derendorf H. Issues in pharmacokinetics and pharmacodynamics of anti-infective agents: kill curves versus MIC. Antimicrobial Agents and Chemotherapy. 48: 369-77. PMID 14742182 DOI: 10.1128/Aac.48.2.369-377.2004  0.781
2004 Liu P, Derendorf H. Antimicrobial tissue concentrations. Infectious Disease Clinics of North America. 17: 599-613. PMID 14711079 DOI: 10.1016/S0891-5520(03)00060-6  0.403
2004 Rohatagi S, Appajosyula S, Derendorf H, Szefler S, Nave R, Zech K, Banerji D. Risk-benefit value of inhaled glucocorticoids: a pharmacokinetic/pharmacodynamic perspective. Journal of Clinical Pharmacology. 44: 37-47. PMID 14681340 DOI: 10.1177/0091270003260334  0.343
2003 Agbenyega T, Planche T, Bedu-Addo G, Ansong D, Owusu-Ofori A, Bhattaram VA, Nagaraja NV, Shroads AL, Henderson GN, Hutson AD, Derendorf H, Krishna S, Stacpoole PW. Population kinetics, efficacy, and safety of dichloroacetate for lactic acidosis due to severe malaria in children. Journal of Clinical Pharmacology. 43: 386-96. PMID 12723459 DOI: 10.1177/0091270003251392  0.357
2003 Nagaraja NV, Pechstein B, Erb K, Klipping C, Hermann R, Locher M, Derendorf H. Pharmacokinetic/pharmacodynamic modeling of luteinizing hormone (LH) suppression and LH surge delay by cetrorelix after single and multiple doses in healthy premenopausal women. Journal of Clinical Pharmacology. 43: 243-51. PMID 12638392 DOI: 10.1177/0091270003251377  0.366
2003 Rojas C, Nagaraja NV, Webb AI, Derendorf H. Microdialysis of triamcinolone acetonide in rat muscle. Journal of Pharmaceutical Sciences. 92: 394-7. PMID 12532388 DOI: 10.1002/Jps.10284  0.347
2003 Persky AM, Müller M, Derendorf H, Grant M, Brazeau GA, Hochhaus G. Single- and multiple-dose pharmacokinetics of oral creatine Journal of Clinical Pharmacology. 43: 29-37. PMID 12520625 DOI: 10.1177/0091270002239703  0.314
2003 EL Desoky ES, Nagaraja NV, Derendorf H. Population pharmacokinetics of digoxin in Egyptian pediatric patients: impact of one data point utilization. American Journal of Therapeutics. 9: 492-8. PMID 12424506 DOI: 10.1097/00045391-200211000-00006  0.301
2003 Bhattaram VA, Graefe U, Kohlert C, Veit M, Derendorf H. Pharmacokinetics and bioavailability of herbal medicinal products. Phytomedicine : International Journal of Phytotherapy and Phytopharmacology. 1-33. PMID 12222652 DOI: 10.1078/1433-187X-00210  0.337
2003 Kohlert C, Schindler G, März RW, Abel G, Brinkhaus B, Derendorf H, Gräfe EU, Veit M. Systemic availability and pharmacokinetics of thymol in humans. Journal of Clinical Pharmacology. 42: 731-7. PMID 12092740 DOI: 10.1177/009127002401102678  0.386
2002 Liu P, Müller M, Grant M, Webb AI, Obermann B, Derendorf H. Interstitial tissue concentrations of cefpodoxime. The Journal of Antimicrobial Chemotherapy. 50: 19-22. PMID 12077156 DOI: 10.1093/Jac/Dkf804  0.381
2002 Meibohm B, Beierle I, Derendorf H. How important are gender differences in pharmacokinetics? Clinical Pharmacokinetics. 41: 329-42. PMID 12036391 DOI: 10.2165/00003088-200241050-00002  0.318
2002 Mouton JW, Dudley MN, Cars O, Derendorf H, Drusano GL. Standardization of pharmacokinetic/pharmacodynamic (PK/PD) terminology for anti-infective drugs. International Journal of Antimicrobial Agents. 19: 355-8. PMID 11978507 DOI: 10.1016/S0924-8579(02)00031-6  0.332
2002 Liu P, Müller M, Derendorf H. Rational dosing of antibiotics: the use of plasma concentrations versus tissue concentrations. International Journal of Antimicrobial Agents. 19: 285-90. PMID 11978499 DOI: 10.1016/S0924-8579(02)00024-9  0.415
2002 de lP, Brunner M, Eichler HG, Rehak E, Gross J, Thyroff-Friesinger U, Müller M, Derendorf H. Comparative target site pharmacokinetics of immediate- and modified-release formulations of cefaclor in humans. Journal of Clinical Pharmacology. 42: 403-11. PMID 11936565 DOI: 10.1177/00912700222011454  0.403
2002 Meibohm B, Derendorf H. Pharmacokinetic/pharmacodynamic studies in drug product development. Journal of Pharmaceutical Sciences. 91: 18-31. PMID 11782894 DOI: 10.1002/Jps.1167  0.381
2002 Erb K, Junge K, Pechstein B, Schneider E, Derendorf H, Hermann R. Novel Formulations of Cetrorelix Acetate in Healthy Men: Pharmacodynamic Effects and Noncompartmental Pharmacokinetics The Journal of Clinical Pharmacology. 42: 995-1001. DOI: 10.1177/009127000204200906  0.372
2001 Möllmann H, Wagner M, Krishnaswami S, Dimova H, Tang Y, Falcoz C, Daley-Yates PT, Krieg M, Stöckmann R, Barth J, Lawlor C, Möllmann AC, Derendorf H, Hochhaus G. Single-dose and steady-state pharmacokinetic and pharmacodynamic evaluation of therapeutically clinically equivalent doses of inhaled fluticasone propionate and budesonide, given as Diskus or Turbohaler dry-powder inhalers to healthy subjects. Journal of Clinical Pharmacology. 41: 1329-38. PMID 11762560 DOI: 10.1177/00912700122012913  0.689
2001 Joukhadar C, Derendorf H, Müller M. Microdialysis. A novel tool for clinical studies of anti-infective agents. European Journal of Clinical Pharmacology. 57: 211-219. PMID 11497336 DOI: 10.1007/S002280100301  0.412
2001 Derendorf H, Hochhaus G, Möllmann H. Evaluation of pulmonary absorption using pharmacokinetic methods Journal of Aerosol Medicine: Deposition, Clearance, and Effects in the Lung. 14. PMID 11424896 DOI: 10.1089/08942680150506295  0.337
2001 Tromm A, Möllmann H, Barth J, Hochhaus G, Krieg M, Bigalke C, Möllmann A, Derendorf H. Pharmacokinetics and rectal bioavailability of hydrocortisone acetate after single and multiple administration in healthy subjects and patients Journal of Clinical Pharmacology. 41: 536-541. PMID 11361050 DOI: 10.1177/00912700122010410  0.367
2001 Graefe EU, Wittig J, Mueller S, Riethling AK, Uehleke B, Drewelow B, Pforte H, Jacobasch G, Derendorf H, Veit M. Pharmacokinetics and bioavailability of quercetin glycosides in humans. Journal of Clinical Pharmacology. 41: 492-9. PMID 11361045 DOI: 10.1177/00912700122010366  0.351
2001 Krishna S, Nagaraja NV, Planche T, Agbenyega T, Bedo-Addo G, Ansong D, Owusu-Ofori A, Shroads AL, Henderson G, Hutson A, Derendorf H, Stacpoole PW. Population pharmacokinetics of intramuscular quinine in children with severe malaria. Antimicrobial Agents and Chemotherapy. 45: 1803-9. PMID 11353629 DOI: 10.1128/Aac.45.6.1803-1809.2001  0.322
2001 Derendorf H, Daley-Yates PT, Pierre LN, Efthimiou J. Systemic bioavailability of inhaled steroids: the importance of appropriate and comparable methodology. The European Respiratory Journal. 17: 157-8. PMID 11307748 DOI: 10.1183/09031936.01.17101570  0.399
2001 Hochhaus G, Barth J, Al-Fayoumi S, Suarez S, Derendorf H, Hochhaus R, Möllmann H. Pharmacokinetics and pharmacodynamics of dexamethasone sodium-m-sulfobenzoate (DS) after intravenous and intramuscular administration: A comparison with dexamethasone phosphate (DP) Journal of Clinical Pharmacology. 41: 425-434. PMID 11304899 DOI: 10.1177/00912700122010285  0.337
2001 Kovar A, Peters T, Beier N, Derendorf H. Pharmacokinetic/pharmacodynamic evaluation of the NHE inhibitor eniporide. Journal of Clinical Pharmacology. 41: 139-48. PMID 11210393 DOI: 10.1177/00912700122009944  0.444
2000 Krishnaswami S, Hochhaus G, Derendorf H. An interactive algorithm for the assessment of cumulative cortisol suppression during inhaled corticosteroid therapy. Aaps Pharmsci. 2: E22. PMID 11741238 DOI: 10.1208/Ps020322  0.699
2000 de la Peña A, Liu P, Derendorf H. Microdialysis in peripheral tissues. Advanced Drug Delivery Reviews. 45: 189-216. PMID 11108974 DOI: 10.1016/S0169-409X(00)00106-X  0.325
2000 Delacher S, Derendorf H, Hollenstein U, Brunner M, Joukhadar C, Hofmann S, Georgopoulos A, Eichler HG, Müller M. A combined in vivo pharmacokinetic-in vitro pharmacodynamic approach to simulate target site pharmacodynamics of antibiotics in humans. The Journal of Antimicrobial Chemotherapy. 46: 733-9. PMID 11062192 DOI: 10.1093/Jac/46.5.733  0.445
2000 Derendorf H, Hochhaus G, Krishnaswami S, Meibohm B, Möllmann H. Optimized therapeutic ratio of inhaled corticosteroids using retrometabolism. Die Pharmazie. 55: 223-7. PMID 10756545  0.67
2000 Krishnaswami S, Möllmann H, Derendorf H, Hochhaus G. A sensitive LC-MS/MS method for the quantification of fluticasone propionate in human plasma. Journal of Pharmaceutical and Biomedical Analysis. 22: 123-9. PMID 10727131 DOI: 10.1016/S0731-7085(99)00246-0  0.651
2000 Pechstein B, Nagaraja NV, Hermann R, Romeis P, Locher M, Derendorf H. Pharmacokinetic-pharmacodynamic modeling of testosterone and luteinizing hormone suppression by cetrorelix in healthy volunteers. Journal of Clinical Pharmacology. 40: 266-74. PMID 10709155 DOI: 10.1177/00912700022008937  0.364
2000 Schweitzer DH, Le-Brun PP, Krishnaswami S, Derendorf H. Clinical and pharmacological aspects of accidental triamcinolone acetonide overdosage: a case study. The Netherlands Journal of Medicine. 56: 12-6. PMID 10667036  0.666
2000 Derendorf H, Lesko LJ, Chaikin P, Colburn WA, Lee P, Miller R, Powell R, Rhodes G, Stanski D, Venitz J. Pharmacokinetic/pharmacodynamic modeling in drug research and development. The Journal of Clinical Pharmacology. 40: 1399-1418. DOI: 10.1177/009127000004001211  0.409
1999 Meibohm B, Hochhaus G, Möllmann H, Barth J, Wagner M, Krieg M, Stöckmann R, Derendorf H. A pharmacokinetic/pharmacodynamic approach to predict the cumulative cortisol suppression of inhaled corticosteroids Journal of Pharmacokinetics and Biopharmaceutics. 27: 127-147. PMID 10567952 DOI: 10.1023/A:1020670421957  0.409
1999 Mayer BX, Mensik C, Krishnaswami S, Derendorf H, Eichler HG, Schmetterer L, Wolzt M. Pharmacokinetic-pharmacodynamic profile of systemic nitric oxide-synthase inhibition with L-NMMA in humans. British Journal of Clinical Pharmacology. 47: 539-44. PMID 10336578 DOI: 10.1046/J.1365-2125.1999.00930.X  0.628
1999 Derendorf H, Meibohm B. Modeling of pharmacokinetic/pharmacodynamic (PK/PD) relationships: Concepts and perspectives Pharmaceutical Research. 16: 176-185. PMID 10100300 DOI: 10.1023/A:1011907920641  0.404
1999 Dalla Costa T, Nolting A, Kovar A, Derendorf H. Determination of free interstitial concentrations of piperacillin-tazobactam combinations by microdialysis. The Journal of Antimicrobial Chemotherapy. 42: 769-78. PMID 10052901 DOI: 10.1093/Jac/42.6.769  0.433
1999 Modric S, Webb AI, Derendorf H. Pharmacokinetics and pharmacodynamics of tilmicosin in sheep and cattle. Journal of Veterinary Pharmacology and Therapeutics. 21: 444-52. PMID 9885967 DOI: 10.1046/j.1365-2885.1998.00177.x  0.301
1998 Hochhaus G, Fröehlich P, Hochhaus R, Möllmann A, Derendorf H, Möllmann HW. A selective HPLC/RIA for the determination of budesonide Journal of Pharmaceutical and Biomedical Analysis. 17: 1235-1242. PMID 9800642 DOI: 10.1016/S0731-7085(98)00022-3  0.328
1998 Hämmerlein A, Derendorf H, Lowenthal DT. Pharmacokinetic and pharmacodynamic changes in the elderly. Clinical implications. Clinical Pharmacokinetics. 35: 49-64. PMID 9673834 DOI: 10.2165/00003088-199835010-00004  0.309
1998 Sourgens H, Hoerr R, Biber A, Steinbrede H, Derendorf H. KA 672-HCl, a neuronal activator against dementia: tolerability, safety, and preliminary pharmacokinetics after single and multiple oral doses in healthy male and female volunteers. Journal of Clinical Pharmacology. 38: 373-81. PMID 9590466 DOI: 10.1002/J.1552-4604.1998.Tb04438.X  0.374
1998 Derendorf H, Hochhaus G, Meibohm B, Mollmann H, Barth J. Pharmacokinetics and pharmacodynamics of inhaled corticosteroids Journal of Allergy and Clinical Immunology. 101. PMID 9563369 DOI: 10.1016/S0091-6749(98)70156-3  0.323
1998 Möllmann H, Wagner M, Meibohm B, Hochhaus G, Barth J, Stöckmann R, Krieg M, Weisser H, Falcoz C, Derendorf H. Pharmacokinetic and pharmacodynamic evaluation of fluticasone propionate after inhaled administration European Journal of Clinical Pharmacology. 53: 459-467. PMID 9551705 DOI: 10.1007/S002280050407  0.42
1997 Müller M, Rohde B, Kovar A, Georgopoulos A, Eichler HG, Derendorf H. Relationship between serum and free interstitial concentrations of cefodizime and cefpirome in muscle and subcutaneous adipose tissue of healthy volunteers measured by microdialysis. Journal of Clinical Pharmacology. 37: 1108-13. PMID 9506005 DOI: 10.1002/J.1552-4604.1997.Tb04294.X  0.367
1997 Rohatagi S, Barth J, Möllmann H, Hochhaus G, Soldner A, Möllmann C, Derendorf H. Pharmacokinetics of methylprednisolone and prednisolone after single and multiple oral administration Journal of Clinical Pharmacology. 37: 916-925. PMID 9505983 DOI: 10.1002/J.1552-4604.1997.Tb04266.X  0.421
1997 Möllmann H, Derendorf H, Barth J, Meibohm B, Wagner M, Krieg M, Weisser H, Knöller J, Möllmann A, Hochhaus G. Pharmacokinetic/pharmacodynamic evaluation of systemic effects of flunisolide after inhalation Journal of Clinical Pharmacology. 37: 893-903. PMID 9505980 DOI: 10.1002/J.1552-4604.1997.Tb04263.X  0.446
1997 Meibohm B, Hochhaus G, Rohatagi S, Möllmann H, Barth J, Wagner M, Krieg M, Stöckmann R, Derendorf H. Dependency of cortisol suppression on administration time of inhaled corticosteroids Journal of Clinical Pharmacology. 37: 704-710. PMID 9378842 DOI: 10.1002/J.1552-4604.1997.Tb04357.X  0.378
1997 Kovar A, Nolting A, Derendorf H. [Microdialysis for the determination of free drugs in tissues]. Pharmazie in Unserer Zeit. 26: 17-23. PMID 9157461 DOI: 10.1002/Pauz.19970260108  0.318
1997 Henderson GN, Curry SH, Derendorf H, Wright EC, Stacpoole PW. Pharmacokinetics of dichloroacetate in adult patients with lactic acidosis. Journal of Clinical Pharmacology. 37: 416-25. PMID 9156374 DOI: 10.1002/J.1552-4604.1997.Tb04319.X  0.411
1997 Brewster ME, Anderson WR, Meinsma D, Moreno D, Webb AI, Pablo L, Estes KS, Derendorf H, Bodor N, Sawchuk R, Cheung B, Pop E. Intravenous and oral pharmacokinetic evaluation of a 2-hydroxypropyl-beta-cyclodextrin-based formulation of carbamazepine in the dog: comparison with commercially available tablets and suspensions. Journal of Pharmaceutical Sciences. 86: 335-9. PMID 9050802 DOI: 10.1021/Js9602913  0.384
1997 Kovar A, Dalla Costa T, Derendorf H. Comparison of plasma and free tissue levels of ceftriaxone in rats by microdialysis. Journal of Pharmaceutical Sciences. 86: 52-6. PMID 9002459 DOI: 10.1021/Js960244A  0.389
1997 Brewster ME, Anderson WR, Webb AI, Pablo LM, Meinsma D, Moreno D, Derendorf H, Bodor N, Pop E. Evaluation of a brain-targeting zidovudine chemical delivery system in dogs. Antimicrobial Agents and Chemotherapy. 41: 122-8. PMID 8980767 DOI: 10.1128/Aac.41.1.122  0.307
1997 Nolting A, Costa TD, Vistelle R, Rand KH, Derendorf H. Determination of free extracellular concentrations of piperacillin by microdialysis. Journal of Pharmaceutical Sciences. 85: 369-72. PMID 8901070 DOI: 10.1021/Js950304X  0.422
1997 Dalla Costa T, Derendorf H. AUIC--a general target for the optimization of dosing regimens of antibiotics? The Annals of Pharmacotherapy. 30: 1024-8. PMID 8876867 DOI: 10.1177/106002809603000919  0.323
1996 Rohatagi S, Bye A, Falcoz C, Mackie AE, Meibohm B, Möllmann H, Derendorf H. Dynamic modeling of cortisol reduction after inhaled administration of fluticasone propionate Journal of Clinical Pharmacology. 36: 938-941. PMID 8930781 DOI: 10.1002/J.1552-4604.1996.Tb04761.X  0.419
1996 Rohatagi S, Täuber U, Richter K, Derendorf H. Pharmacokinetic/pharmacodynamic modeling of cortisol suppression after oral administration of fluocortolone. Journal of Clinical Pharmacology. 36: 311-4. PMID 8728344 DOI: 10.1002/J.1552-4604.1996.Tb04206.X  0.414
1996 Nolting A, Dalla Costa T, Rand KH, Derendorf H. Pharmacokinetic-pharmacodynamic modeling of the antibiotic effect of piperacillin in vitro. Pharmaceutical Research. 13: 91-6. PMID 8668686 DOI: 10.1023/A:1016085402278  0.349
1996 Derendorf H, Kovar A, Dalla Costa T. Pharmacokinetic/pharmacodynamic modelling of anti-infective activity European Journal of Pharmaceutical Sciences. 4: S59. DOI: 10.1016/S0928-0987(97)86211-2  0.309
1996 Rohatagi S, Bye A, Mackie AE, Derendorf H. Mathematical modeling of cortisol circadian rhythm and cortisol suppression European Journal of Pharmaceutical Sciences. 4: 341-350. DOI: 10.1016/S0928-0987(96)00174-1  0.333
1995 Rohatagi S, Hochhaus G, Mollmann H, Barth J, Galia E, Erdmann M, Sourgens H, Derendorf H. Pharmacokinetic and pharmacodynamic evaluation of triamcinolone acetonide after intravenous, oral, and inhaled administration Journal of Clinical Pharmacology. 35: 1187-1193. PMID 8750370 DOI: 10.1002/J.1552-4604.1995.Tb04045.X  0.416
1995 Derendorf H, Hochhaus G, Rohatagi S, Mollmann H, Barth J, Sourgens H, Erdmann M. Pharmacokinetics of triamcinolone acetonide after intravenous, oral, and inhaled administration Journal of Clinical Pharmacology. 35: 302-305. PMID 7608322 DOI: 10.1002/J.1552-4604.1995.Tb04064.X  0.395
1995 Möllmann H, Hochhaus G, Rohatagi S, Barth J, Derendorf H. Pharmacokinetic/Pharmacodynamic Evaluation of Deflazacort in Comparison to Methylprednisolone and Prednisolone Pharmaceutical Research: An Official Journal of the American Association of Pharmaceutical Scientists. 12: 1096-1100. PMID 7494809 DOI: 10.1023/A:1016287104656  0.424
1994 Derendorf H. Pharmacokinetic/pharmacodynamic consequences of space flight. Journal of Clinical Pharmacology. 34: 684-91. PMID 8083401 DOI: 10.1002/J.1552-4604.1994.Tb02024.X  0.344
1994 Schreier H, McNicol KJ, Bennett DB, Teitelbaum Z, Derendorf H. Pharmacokinetics of detirelix following intratracheal instillation and aerosol inhalation in the unanesthetized awake sheep. Pharmaceutical Research. 11: 1056-9. PMID 7937548 DOI: 10.1023/A:1018951824315  0.418
1994 Henderson GN, Whalen PO, Darr RA, Curry SH, Derendorf H, Baumgartner TG, Stacpoole PW. Development of an Oral Drug Formulation for Dichloroacetate and Thiamine Drug Development and Industrial Pharmacy. 20: 2425-2437. DOI: 10.3109/03639049409042647  0.328
1994 Derendorf H. Pharmacodynamic Aspects of Systemic Drug Delivery Drug Development and Industrial Pharmacy. 20: 485-502. DOI: 10.3109/03639049409038314  0.389
1994 Mies RJM, Aa JJvd, Dixon CL, Kaltenbach M, Derendorf H, Gravenstein N. Computer-modulated patient-controlled analgesia. Preliminary evaluation of a prototype. Regional Anesthesia. 19: 270-276. DOI: 10.1136/Rapm-00115550-199419040-00009  0.358
1993 Derendorf H, Hochhaus G, Mollmann H, Barth J, Krieg M, Tunn S, Mollmann C. Receptor-based pharmacokinetic-pharmacodynamic analysis of corticosteroids Journal of Clinical Pharmacology. 33: 115-123. PMID 8440759 DOI: 10.1002/J.1552-4604.1993.Tb03930.X  0.385
1993 Barth J, Lehr KH, Derendorf H, Mollmann HW, Hohler T, Hochhaus G. Studies on the pharmacokinetics and metabolism of prednicarbate after cutaneous and oral administration Skin Pharmacology. 6: 179-186. PMID 8274287 DOI: 10.1159/000211133  0.329
1993 Mohammed SS, Ayass M, Mehta P, Kedar A, Gross S, Derendorf H. Codeine disposition in sickle cell patients compared with healthy volunteers. Journal of Clinical Pharmacology. 33: 811-5. PMID 8227477 DOI: 10.1002/J.1552-4604.1993.Tb01956.X  0.4
1993 Mohammed SS, Butschkau M, Derendorf H. A Reversed Phase Liquid Chromatographic Method for the Determination of Codeine in Biological Fluids with Applications Journal of Liquid Chromatography. 16: 2325-2334. DOI: 10.1080/10826079308020989  0.324
1992 Makil O, Kaltenbach ML, Limberg J, Harrison D, Hocking MP, Derendorf H. Pharmacokinetics of ranitidine after partial gastrectomy in dogs. Journal of Pharmaceutical Sciences. 80: 1034-6. PMID 1815053 DOI: 10.1002/Jps.2600801107  0.368
1992 Möllmann H, Barth J, Möllmann C, Tunn S, Krieg M, Derendorf H. Pharmacokinetics and rectal bioavailability of hydrocortisone acetate. Journal of Pharmaceutical Sciences. 80: 835-6. PMID 1800704 DOI: 10.1002/Jps.2600800906  0.39
1992 Estes KS, Keuth V, Dietzel K, Brewster ME, Bodor NS, Derendorf H. A redox-based chemical delivery system that enhances estradiol distribution to the brain: disposition studies in the rat. Pharmaceutical Research. 8: 1180-5. PMID 1788164 DOI: 10.1023/A:1015814720778  0.307
1992 Rand KH, Gibbs K, Derendorf H, Graham-Pole J. Pharmacokinetics of intravenous immunoglobulin (Gammagard) in bone marrow transplant patients. Journal of Clinical Pharmacology. 31: 1151-4. PMID 1662233 DOI: 10.1016/0192-0561(91)90388-N  0.323
1992 Hochhaus G, Chen LS, Ratka A, Druzgala P, Howes J, Bodor N, Derendorf H. Pharmacokinetic characterization and tissue distribution of the new glucocorticoid soft drug loteprednol etabonate in rats and dogs Journal of Pharmaceutical Sciences. 81: 1210-1215. PMID 1491342 DOI: 10.1002/Jps.2600811217  0.42
1992 Hochhaus G, Hochhaus R, Werber G, Derendorf H, Möllmann H. A Selective HPLC/RIA for dexamethasone and its prodrug dexamethasone‐21‐sulphobenzoate sodium in biological fluids Biomedical Chromatography. 6: 283-286. PMID 1286285 DOI: 10.1002/Bmc.1130060607  0.318
1992 Tunn S, Möllmann H, Barth J, Derendorf H, Krieg M. Simultaneous Measurement of Cortisol in Serum and Saliva After Different Forms of Cortisol Administration Clinical Chemistry. 38: 1491-1494. DOI: 10.1093/Clinchem/38.8.1491  0.332
1992 Schreier H, McNicol KJ, Ausborn M, Soucy DM, Derendorf H, Stecenko AA, Gonzalez-Rothi RJ. Pulmonary delivery of amikacin liposomes and acute liposome toxicity in the sheep International Journal of Pharmaceutics. 87: 183-193. DOI: 10.1016/0378-5173(92)90242-T  0.365
1991 Brunt E, Limberg J, Derendorf H. High-performance liquid chromatographic assay and erythrocyte partitioning of fleroxacin, a new fluoroquinolone antibiotic. Journal of Pharmaceutical and Biomedical Analysis. 8: 67-71. PMID 2129330 DOI: 10.1016/0731-7085(90)80008-D  0.356
1991 Derendorf H, Möllmann H, Barth J, Möllmann C, Tunn S, Krieg M. Pharmacokinetics and oral bioavailability of hydrocortisone. Journal of Clinical Pharmacology. 31: 473-6. PMID 2050835 DOI: 10.1002/J.1552-4604.1991.Tb01906.X  0.388
1991 Derendorf H, Möllmann H, Krieg M, Tunn S, Möllmann C, Barth J, Röthig HJ. Pharmacodynamics of methylprednisolone phosphate after single intravenous administration to healthy volunteers. Pharmaceutical Research. 8: 263-8. PMID 2023879 DOI: 10.1023/A:1015864709082  0.401
1991 Hochhaus G, Derendorf H, Möllmann H, Barth J. A selective LC/RIA for dexamethasone and its prodrug dexamethasone-21-isonicotinate in biological fluids Journal of Pharmaceutical and Biomedical Analysis. 9: 761-767. PMID 1821154 DOI: 10.1016/0731-7085(91)80218-X  0.324
1990 Schaefer HG, Spahn H, Lopez LM, Derendorf H. Simultaneous determination of propranolol and 4-hydroxypropranolol enantiomers after chiral derivatization using reversed-phase high-performance liquid chromatography Journal of Chromatography B: Biomedical Sciences and Applications. 527: 351-359. PMID 2387882 DOI: 10.1016/S0378-4347(00)82118-0  0.305
1990 Kaltenbach ML, Curry SH, Derendorf H. Extent of drug absorption at the time of peak plasma concentration in an open one-compartment body model with first-order absorption. Journal of Pharmaceutical Sciences. 79: 462. PMID 2352171 DOI: 10.1002/Jps.2600790523  0.365
1990 Schaefer HG, Harrison D, Hocking MP, Limberg J, Derendorf H. Effects of truncal vagotomy and partial gastrectomy on the pharmacokinetics of propranolol enantiomers in dogs. Journal of Pharmaceutical Sciences. 79: 292-4. PMID 2352138 DOI: 10.1002/Jps.2600790404  0.368
1990 Derendorf H, Möllmann H, Voortman G, van den Ouweland FA, van de Putte LB, Gevers G, Dequeker J, van Vliet-Daskalopoulou E. Pharmacokinetics of rimexolone after intra-articular administration. Journal of Clinical Pharmacology. 30: 476-9. PMID 2347958 DOI: 10.1002/J.1552-4604.1990.Tb03488.X  0.38
1990 Dietzel K, Keuth V, Estes KS, Brewster ME, Clemmons RM, Vistelle R, Bodor NS, Derendorf H. A redox-based system that enhances delivery of estradiol to the brain: pharmacokinetic evaluation in the dog. Pharmaceutical Research. 7: 879-83. PMID 2235886 DOI: 10.1023/A:1015977319212  0.352
1990 Limberg J, LeBel M, Derendorf H. Evaluation of free tissue concentrations of fleroxacin after oral administration. Pharmaceutical Research. 7: 422-4. PMID 2114021 DOI: 10.1023/A:1015840027022  0.335
1990 DIETZEL K, ESTES K, BREWSTER M, BODOR N, DERENDORF H. The use of 2-hydroxypropyl-β-cyclodextrin as a vehicle for intravenous administration of dexamethasone in dogs International Journal of Pharmaceutics. 59: 225-230. DOI: 10.1016/0378-5173(90)90113-I  0.339
1989 Mullersman G, Derendorf H, Brewster ME, Estes KS, Bodor N. High-performance liquid chromatographic assay of a central nervous system (CNS)-directed estradiol chemical delivery system and its application after intravenous administration to rats. Pharmaceutical Research. 5: 172-7. PMID 3244629 DOI: 10.1023/A:1015964907110  0.307
1989 Möllmann H, Rohdewald P, Barth J, Möllmann C, Verho M, Derendorf H. Comparative pharmacokinetics of methylprednisolone phosphate and hemisuccinate in high doses. Pharmaceutical Research. 5: 509-13. PMID 3072558 DOI: 10.1023/A:1015921408870  0.373
1989 Möllmann H, Rohdewald P, Barth J, Verho M, Derendorf H. Pharmacokinetics and dose linearity testing of methylprednisolone phosphate. Biopharmaceutics & Drug Disposition. 10: 453-64. PMID 2804250 DOI: 10.1002/Bdd.2510100504  0.386
1989 Derendorf H. Pharmacokinetic evaluation of beta-lactam antibiotics. The Journal of Antimicrobial Chemotherapy. 24: 407-13. PMID 2681120 DOI: 10.1093/Jac/24.3.407  0.367
1987 Mullersman G, Gotz VP, Russell WL, Derendorf H. Lack of clinically significant in vitro and in vivo interactions between ranitidine and sucralfate. Journal of Pharmaceutical Sciences. 75: 995-8. PMID 3795033 DOI: 10.1002/Jps.2600751018  0.375
1987 Derendorf H, Mullersman G, Barth J, Grüner A, Möllmann H. Pharmacokinetics of diclofenac sodium after intramuscular administration in combination with triamcinolone acetate. European Journal of Clinical Pharmacology. 31: 363-5. PMID 3792436 DOI: 10.1007/Bf00981139  0.368
1987 Rohdewald P, Möllmann H, Barth J, Rehder J, Derendorf H. Pharmacokinetics of dexamethasone and its phosphate ester. Biopharmaceutics & Drug Disposition. 8: 205-12. PMID 3593899 DOI: 10.1002/Bdd.2510080302  0.392
1987 Stout SA, Derendorf H. Local treatment of respiratory infections with antibiotics. Drug Intelligence & Clinical Pharmacy. 21: 322-9. PMID 3552545 DOI: 10.1177/106002808702100402  0.343
1987 Derendorf H. Erythrocyte binding of cephalosporins. The Journal of Pharmacy and Pharmacology. 39: 129-31. PMID 2881998 DOI: 10.1111/J.2042-7158.1987.Tb06959.X  0.327
1986 Derendorf H, Rohdewald P, Möllmann H, Rehder J, Barth J, Neveling D. Pharmacokinetics of prednisolone after high doses of prednisolone hemisuccinate. Biopharmaceutics & Drug Disposition. 6: 423-32. PMID 4084667 DOI: 10.1002/Bdd.2510060408  0.397
1986 Derendorf H, Möllmann H, Grüner A, Haack D, Gyselby G. Pharmacokinetics and pharmacodynamics of glucocorticoid suspensions after intra-articular administration. Clinical Pharmacology and Therapeutics. 39: 313-7. PMID 3948470 DOI: 10.1038/Clpt.1986.45  0.363
1986 Mullersman G, Derendorf H. Rapid analysis of ranitidine in biological fluids and determination of its erythrocyte partitioning. Journal of Chromatography. 381: 385-91. PMID 3760093 DOI: 10.1016/S0378-4347(00)83604-X  0.361
1986 Derendorf H, Rohdewald P, Hochhaus G, Möllmann H. HPLC determination of glucocorticoid alcohols, their phosphates and hydrocortisone in aqueous solutions and biological fluids Journal of Pharmaceutical and Biomedical Analysis. 4: 197-206. DOI: 10.1016/0731-7085(86)80042-5  0.326
1985 Garrett ER, Derendorf H, Mattha AG. Pharmacokinetics of morphine and its surrogates. VII: High-performance liquid chromatographic analyses and pharmacokinetics of methadone and its derived metabolites in dogs. Journal of Pharmaceutical Sciences. 74: 1203-14. PMID 4087182 DOI: 10.1002/Jps.2600741114  0.388
1985 Möllmann H, Rohdewald P, Schmidt EW, Salomon V, Derendorf H. Pharmacokinetics of triamcinolone acetonide and its phosphate ester. European Journal of Clinical Pharmacology. 29: 85-9. PMID 4054209 DOI: 10.1007/Bf00547374  0.379
1985 Yost RL, Derendorf H. Rapid chromatographic determination of cefotaxime and its metabolite in biological fluids. Journal of Chromatography. 341: 131-8. PMID 3894403 DOI: 10.1016/S0378-4347(00)84017-7  0.329
1985 Derendorf H, Möllmann H, Rohdewald P, Rehder J, Schmidt EW. Kinetics of methylprednisolone and its hemisuccinate ester. Clinical Pharmacology and Therapeutics. 37: 502-7. PMID 3886255 DOI: 10.1038/Clpt.1985.79  0.359
1985 Rohdewald P, Rehder J, Drehsen G, Hochhaus G, Derendorf H, Möllmann H. Simultaneous determination of glucocorticoid alcohols, their succinates and hydrocortisone in plasma Journal of Pharmaceutical and Biomedical Analysis. 3: 566-573. DOI: 10.1016/0731-7085(85)80074-1  0.312
1984 Derendorf H, El-Din A, El-Koussi A, Garrett ER. Electrochemical chromatographic determinations of morphine antagonists in biological fluids, with applications. Journal of Pharmaceutical Sciences. 73: 621-4. PMID 6737235 DOI: 10.1002/Jps.2600730510  0.314
1983 Derendorf H, Garrett ER. High-performance liquid chromatographic assay of methadone, phencyclidine, and metabolites by postcolumn ion-pair extraction and on-line fluorescent detection of the counterion with applications. Journal of Pharmaceutical Sciences. 72: 630-5. PMID 6875824 DOI: 10.1002/Jps.2600720613  0.312
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