Atsushi Takeda, MD, PhD - Publications

Affiliations: 
Medical Biochemistry Tohoku University, Sendai-shi, Miyagi-ken, Japan 
Area:
http://www.biomedexperts.com/Profile.bme/1388341/Atsushi_Takeda
Website:
http://www.labome.org/expert/japan/university/takeda/atsushi-takeda-195538.html

151 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2019 Tamano H, Sato Y, Takiguchi M, Murakami T, Fukuda T, Kawagishi H, Suzuki M, Takeda A. CA1 LTP Attenuated by Corticosterone is Canceled by Effusol via Rescuing Intracellular Zn Dysregulation. Cellular and Molecular Neurobiology. PMID 31147851 DOI: 10.1007/s10571-019-00693-5  0.44
2019 Tamano H, Nishio R, Morioka H, Furuhata R, Komata Y, Takeda A. Paraquat as an Environmental Risk Factor in Parkinson's Disease Accelerates Age-Related Degeneration Via Rapid Influx of Extracellular Zn into Nigral Dopaminergic Neurons. Molecular Neurobiology. PMID 31119555 DOI: 10.1007/s12035-019-01642-5  0.44
2019 Tamano H, Oneta N, Shioya A, Adlard PA, Bush AI, Takeda A. In vivo synaptic activity-independent co-uptakes of amyloid β and Zn into dentate granule cells in the normal brain. Scientific Reports. 9: 6498. PMID 31019269 DOI: 10.1038/s41598-019-43012-0  0.44
2019 Ezura M, Kikuchi A, Ishiki A, Okamura N, Hasegawa T, Harada R, Watanuki S, Funaki Y, Hiraoka K, Baba T, Sugeno N, Oshima R, Yoshida S, Kobayashi J, Kobayashi M, ... ... Takeda A, et al. Longitudinal changes in F-THK5351 PET in corticobasal syndrome. European Journal of Neurology. PMID 30980575 DOI: 10.1111/ene.13966  0.32
2019 Nishio R, Tamano H, Morioka H, Takeuchi A, Takeda A. Intake of Heated Leaf Extract of Coriandrum sativum Contributes to Resistance to Oxidative Stress via Decreases in Heavy Metal Concentrations in the Kidney. Plant Foods For Human Nutrition (Dordrecht, Netherlands). PMID 30783906 DOI: 10.1007/s11130-019-00720-2  0.44
2019 Tamano H, Suzuki H, Kobuchi S, Adlard PA, Bush AI, Takeda A. Difference in ability for extracellular Zn influx between human and rat amyloid β and its significance. Neurotoxicology. PMID 30664975 DOI: 10.1016/j.neuro.2019.01.005  0.44
2018 Tamano H, Suzuki H, Murakami T, Fujii H, Adlard PA, Bush AI, Takeda A. Amyloid β-Induced Rapid Zn Influx into Dentate Granule Cells Attenuates Maintained LTP Followed by Retrograde Amnesia. Molecular Neurobiology. PMID 30460616 DOI: 10.1007/s12035-018-1429-6  0.44
2018 Tamano H, Morioka H, Nishio R, Takeuchi A, Takeda A. Blockade of Rapid Influx of Extracellular Zn into Nigral Dopaminergic Neurons Overcomes Paraquat-Induced Parkinson's Disease in Rats. Molecular Neurobiology. PMID 30341553 DOI: 10.1007/s12035-018-1398-9  0.44
2018 Tamano H, Morioka H, Nishio R, Takeuchi A, Takeda A. AMPA-induced extracellular Zn influx into nigral dopaminergic neurons causes movement disorder in rats. Neurotoxicology. 69: 23-28. PMID 30176255 DOI: 10.1016/j.neuro.2018.08.008  0.44
2018 Tamano H, Kubota M, Fujise Y, Shimaya R, Itoh R, Suzuki M, Adlard PA, Bush AI, Takeda A. Adrenergic β receptor activation in the basolateral amygdala, which is intracellular Zn-dependent, rescues amyloid β-induced attenuation of dentate gyrus LTP. Neurochemistry International. PMID 30030113 DOI: 10.1016/j.neuint.2018.07.005  0.44
2018 Takeda A, Tamano H. Is Vulnerability of the Dentate Gyrus to Aging and Amyloid-β Neurotoxicity Linked with Modified Extracellular Zn Dynamics? Biological & Pharmaceutical Bulletin. 41: 995-1000. PMID 29962410 DOI: 10.1248/bpb.b17-00871  0.44
2018 Suzuki M, Sato Y, Tamura K, Tamano H, Takeda A. Rapid Intracellular Zn Dysregulation via Membrane Corticosteroid Receptor Activation Affects In Vivo CA1 LTP. Molecular Neurobiology. PMID 29948940 DOI: 10.1007/s12035-018-1159-9  0.44
2018 Tamano H, Morioka H, Iwaki H, Suzuki H, Sato Y, Takeda A. Yokukansan, a Herbal Medicine in Japan, Buffers Social Crowding Stress via Ameliorating Glucocorticoid Secretion Response to Vasopressin. Biological & Pharmaceutical Bulletin. 41: 920-924. PMID 29863081 DOI: 10.1248/bpb.b18-00052  0.44
2018 Tamano H, Nishio R, Morioka H, Takeda A. Extracellular Zn Influx into Nigral Dopaminergic Neurons Plays a Key Role for Pathogenesis of 6-Hydroxydopamine-Induced Parkinson's Disease in Rats. Molecular Neurobiology. PMID 29705946 DOI: 10.1007/s12035-018-1075-z  0.44
2018 Takeda A, Tamano H, Hashimoto W, Kobuchi S, Suzuki H, Murakami T, Tempaku M, Koike Y, Adlard PA, Bush AI. Novel Defense by Metallothionein Induction Against Cognitive Decline: From Amyloid β-Induced Excess Znto Functional ZnDeficiency. Molecular Neurobiology. PMID 29460269 DOI: 10.1007/s12035-018-0948-5  0.44
2018 Yoshida S, Hasegawa T, Suzuki M, Sugeno N, Kobayashi J, Ueyama M, Fukuda M, Ido-Fujibayashi A, Sekiguchi K, Ezura M, Kikuchi A, Baba T, Takeda A, Mochizuki H, Nagai Y, et al. Parkinson's disease-linked DNAJC13 mutation aggravates alpha-synuclein-induced neurotoxicity through perturbation of endosomal trafficking. Human Molecular Genetics. PMID 29309590 DOI: 10.1093/hmg/ddy003  0.32
2017 Takeda A, Tamano H. The Impact of Synaptic Zn(2+) Dynamics on Cognition and Its Decline. International Journal of Molecular Sciences. 18. PMID 29135924 DOI: 10.3390/ijms18112411  0.44
2017 Takeda A, Tamano H, Tempaku M, Sasaki M, Uematsu C, Sato S, Kanazawa H, Datki ZL, Adlard PA, Bush AI. Extracellular Zn(2+) is essential for amyloid β1-42-induced cognitive decline in the normal brain and its rescue. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. PMID 28652412 DOI: 10.1523/JNEUROSCI.0954-17.2017  0.44
2017 Takeda A, Tamano H, Murakami T, Nakada H, Minamino T, Koike Y. Weakened Intracellular Zn(2+)-Buffering in the Aged Dentate Gyrus and Its Involvement in Erasure of Maintained LTP. Molecular Neurobiology. PMID 28547527 DOI: 10.1007/s12035-017-0615-2  0.44
2017 Tamano H, Nishio R, Takeda A. Involvement of intracellular Zn(2+) signaling in LTP at perforant pathway-CA1 pyramidal cell synapse. Hippocampus. PMID 28380662 DOI: 10.1002/hipo.22730  0.44
2017 Takeda A, Koike Y, Osaw M, Tamano H. Characteristic of Extracellular Zn(2+) Influx in the Middle-Aged Dentate Gyrus and Its Involvement in Attenuation of LTP. Molecular Neurobiology. PMID 28290149 DOI: 10.1007/s12035-017-0472-z  0.44
2017 Tamano H, Nishio R, Shakushi Y, Sasaki M, Koike Y, Osawa M, Takeda A. In vitro and in vivo physiology of low nanomolar concentrations of Zn(2+) in artificial cerebrospinal fluid. Scientific Reports. 7: 42897. PMID 28211543 DOI: 10.1038/srep42897  0.44
2017 Takeda A, Tamano H, Hisatsune M, Murakami T, Nakada H, Fujii H. Maintained LTP and Memory Are Lost by Zn(2+) Influx into Dentate Granule Cells, but Not Ca(2+) Influx. Molecular Neurobiology. PMID 28176276 DOI: 10.1007/s12035-017-0428-3  0.44
2017 Fujise Y, Kubota M, Suzuki M, Tamano H, Takeda A. Blockade of intracellular Zn(2+) signaling in the basolateral amygdala affects object recognition memory via attenuation of dentate gyrus LTP. Neurochemistry International. PMID 28131899 DOI: 10.1016/j.neuint.2017.01.014  0.44
2017 Baba T, Hosokai Y, Nishio Y, Kikuchi A, Hirayama K, Suzuki K, Hasegawa T, Aoki M, Takeda A, Mori E. Longitudinal study of cognitive and cerebral metabolic changes in Parkinson's disease. Journal of the Neurological Sciences. 372: 288-293. PMID 28017230 DOI: 10.1016/j.jns.2016.11.068  0.32
2016 Kikuchi A, Okamura N, Hasegawa T, Harada R, Watanuki S, Funaki Y, Hiraoka K, Baba T, Sugeno N, Oshima R, Yoshida S, Kobayashi J, Ezura M, Kobayashi M, Tano O, ... ... Takeda A, et al. In vivo visualization of tau deposits in corticobasal syndrome by 18F-THK5351 PET. Neurology. PMID 27794115 DOI: 10.1212/WNL.0000000000003375  0.32
2016 Kuroda H, Mukai Y, Nishiyama S, Takeshita T, Tateyama M, Takeda A, Aoki M. Tardily accelerated neurologic deterioration in two-step thallium intoxication. Journal of Clinical Neuroscience : Official Journal of the Neurosurgical Society of Australasia. PMID 27692615 DOI: 10.1016/j.jocn.2016.09.003  0.36
2016 Takeda A, Tamano H, Nishio R, Murakami T. Behavioral Abnormality Induced by Enhanced Hypothalamo-Pituitary-Adrenocortical Axis Activity under Dietary Zinc Deficiency and Its Usefulness as a Model. International Journal of Molecular Sciences. 17. PMID 27438830 DOI: 10.3390/ijms17071149  0.44
2016 Tamano H, Ide K, Adlard PA, Bush AI, Takeda A. Involvement of hippocampal excitability in amyloid β-induced behavioral and psychological symptoms of dementia. The Journal of Toxicological Sciences. 41: 449-57. PMID 27432231 DOI: 10.2131/jts.41.449  0.44
2016 Kikuchi A, Takeda A, Sugeno N, Miura E, Kato K, Hasegawa T, Baba T, Konno M, Oshima R, Watanuki S, Hiraoka K, Tashiro M, Aoki M. Brain Metabolic Changes of Cervical Dystonia with Spinocerebellar Ataxia Type 1 after Botulinum Toxin Therapy. Internal Medicine (Tokyo, Japan). 55: 1919-22. PMID 27432104 DOI: 10.2169/internalmedicine.55.5843  0.32
2016 Takeda A, Tamano H. Insight into cognitive decline from Zn(2+) dynamics through extracellular signaling of glutamate and glucocorticoids. Archives of Biochemistry and Biophysics. PMID 27392455 DOI: 10.1016/j.abb.2016.06.021  0.44
2016 Takeda A, Tamano H. Innervation from the entorhinal cortex to the dentate gyrus and the vulnerability to Zn(2.) Journal of Trace Elements in Medicine and Biology : Organ of the Society For Minerals and Trace Elements (Gms). PMID 27267970 DOI: 10.1016/j.jtemb.2016.05.006  0.44
2016 Tamano H, Yusuke E, Ide K, Takeda A. Influences of Yokukansankachimpihange on aggressive behavior of zinc-deficient mice and actions of the ingredients on excessive neural exocytosis in the hippocampus of zinc-deficient rats. Experimental Animals / Japanese Association For Laboratory Animal Science. PMID 27245118 DOI: 10.1538/expanim.16-0028  0.44
2016 Oshima R, Hasegawa T, Tamai K, Sugeno N, Yoshida S, Kobayashi J, Kikuchi A, Baba T, Futatsugi A, Sato I, Satoh K, Takeda A, Aoki M, Tanaka N. ESCRT-0 dysfunction compromises autophagic degradation of protein aggregates and facilitates ER stress-mediated neurodegeneration via apoptotic and necroptotic pathways. Scientific Reports. 6: 24997. PMID 27112194 DOI: 10.1038/srep24997  0.32
2016 Odagiri H, Baba T, Nishio Y, Iizuka O, Matsuda M, Inoue K, Kikuchi A, Hasegawa T, Aoki M, Takeda A, Taki Y, Mori E. On the Utility of MIBG SPECT/CT in Evaluating Cardiac Sympathetic Dysfunction in Lewy Body Diseases. Plos One. 11: e0152746. PMID 27055151 DOI: 10.1371/journal.pone.0152746  0.32
2016 Tamano H, Koike Y, Nakada H, Shakushi Y, Takeda A. Significance of synaptic Zn(2+) signaling in zincergic and non-zincergic synapses in the hippocampus in cognition. Journal of Trace Elements in Medicine and Biology : Organ of the Society For Minerals and Trace Elements (Gms). PMID 26995290 DOI: 10.1016/j.jtemb.2016.03.003  0.44
2016 Takeda A, Tamano H. Significance of Low Nanomolar Concentration of Zn(2+) in Artificial Cerebrospinal Fluid. Molecular Neurobiology. PMID 26984599 DOI: 10.1007/s12035-016-9816-3  0.44
2016 Yoshihara A, Fukatsu M, Hoshi K, Ito H, Nollet K, Yamaguchi Y, Ishii R, Tokuda T, Miyajima M, Arai H, Kato T, Furukawa K, Arai H, Kikuchi A, Takeda A, et al. Subgroup differences in "brain-type" transferrin and α-synuclein in Parkinson's disease and multiple system atrophy. Journal of Biochemistry. PMID 26970280 DOI: 10.1093/jb/mvw015  0.32
2016 Zhang Y, Abe K, Haga Y, Hayato Y, Ikeda M, Iyogi K, Kameda J, Kishimoto Y, Miura M, Moriyama S, Nakahata M, Nakajima T, Nakano Y, Nakayama S, Orii A, ... ... Takeda A, et al. First measurement of radioactive isotope production through cosmic-ray muon spallation in Super-Kamiokande IV Physical Review D - Particles, Fields, Gravitation and Cosmology. 93. DOI: 10.1103/PhysRevD.93.012004  0.32
2015 Takeda A, Tamano H. Significance of the degree of synaptic Zn(2+) signaling in cognition. Biometals : An International Journal On the Role of Metal Ions in Biology, Biochemistry, and Medicine. PMID 26704989 DOI: 10.1007/s10534-015-9907-z  0.44
2015 Tamano H, Shakushi Y, Watanabe M, Ohashi K, Uematsu C, Otsubo T, Ikeda K, Takeda A. Preventive Effect of 3,5-dihydroxy-4-methoxybenzyl Alcohol (DHMBA) and Zinc, Components of the Pacific Oyster Crassostrea gigas, on Glutamatergic Neuron Activity in the Hippocampus. The Biological Bulletin. 229: 282-8. PMID 26695827 DOI: 10.7567/JJAP.55.09SC01  0.44
2015 Takhistov V, Abe K, Haga Y, Hayato Y, Ikeda M, Iyogi K, Kameda J, Kishimoto Y, Miura M, Moriyama S, Nakahata M, Nakajima T, Nakano Y, Nakayama S, Orii A, ... ... Takeda A, et al. Search for Nucleon and Dinucleon Decays with an Invisible Particle and a Charged Lepton in the Final State at the Super-Kamiokande Experiment. Physical Review Letters. 115: 121803. PMID 26430987 DOI: 10.1103/PhysRevLett.115.121803  0.32
2015 Takeda A, Shakushi Y, Tamano H. Modification of hippocampal excitability in brain slices pretreated with a low nanomolar concentration of Zn(2.). Journal of Neuroscience Research. 93: 1641-7. PMID 26268632 DOI: 10.1002/jnr.23629  0.44
2015 Takeda A, Suzuki M, Tempaku M, Ohashi K, Tamano H. Influx of extracellular Zn(2+) into the hippocampal CA1 neurons is required for cognitive performance via long-term potentiation. Neuroscience. 304: 209-16. PMID 26204819 DOI: 10.1016/j.neuroscience.2015.07.042  0.44
2015 Suzuki M, Fujise Y, Tsuchiya Y, Tamano H, Takeda A. Excess influx of Zn(2+) into dentate granule cells affects object recognition memory via attenuated LTP. Neurochemistry International. 87: 60-5. PMID 26044210 DOI: 10.1016/j.neuint.2015.05.006  0.44
2015 Tamano H, Takeda A. Is interaction of amyloid β-peptides with metals involved in cognitive activity? Metallomics : Integrated Biometal Science. 7: 1205-12. PMID 25959547 DOI: 10.1039/c5mt00076a  0.44
2015 Choi K, Abe K, Haga Y, Hayato Y, Iyogi K, Kameda J, Kishimoto Y, Miura M, Moriyama S, Nakahata M, Nakano Y, Nakayama S, Sekiya H, Shiozawa M, Suzuki Y, ... Takeda A, et al. Search for neutrinos from annihilation of captured low-mass dark matter particles in the sun by super-kamiokande. Physical Review Letters. 114: 141301. PMID 25910107 DOI: 10.1103/PhysRevLett.114.141301  0.32
2015 Takeda A, Tamano H. Regulation of extracellular Zn(2+) homeostasis in the hippocampus as a therapeutic target for Alzheimer's disease. Expert Opinion On Therapeutic Targets. 19: 1051-8. PMID 25818846 DOI: 10.1517/14728222.2015.1029454  0.44
2015 Tsai SH, Kinoshita M, Kusu T, Kayama H, Okumura R, Ikeda K, Shimada Y, Takeda A, Yoshikawa S, Obata-Ninomiya K, Kurashima Y, Sato S, Umemoto E, Kiyono H, Karasuyama H, et al. The ectoenzyme E-NPP3 negatively regulates ATP-dependent chronic allergic responses by basophils and mast cells. Immunity. 42: 279-93. PMID 25692702 DOI: 10.1016/j.immuni.2015.01.015  0.36
2015 Tamano H, Minamino T, Fujii H, Takada S, Nakamura M, Ando M, Takeda A. Blockade of intracellular Zn(2+) signaling in the dentate gyrus erases recognition memory via impairment of maintained LTP. Hippocampus. 25: 952-62. PMID 25603776 DOI: 10.1002/hipo.22418  0.88
2015 Gustafson J, Abe K, Haga Y, Hayato Y, Ikeda M, Iyogi K, Kameda J, Kishimoto Y, Miura M, Moriyama S, Nakahata M, Nakajima T, Nakano Y, Nakayama S, Orii A, ... ... Takeda A, et al. Search for dinucleon decay into pions at Super-Kamiokande Physical Review D - Particles, Fields, Gravitation and Cosmology. 91. DOI: 10.1103/PhysRevD.91.072009  0.32
2015 Abe K, Haga Y, Hayato Y, Ikeda M, Iyogi K, Kameda J, Kishimoto Y, Miura M, Moriyama S, Nakahata M, Nakano Y, Nakayama S, Sekiya H, Shiozawa M, Suzuki Y, ... Takeda A, et al. Limits on sterile neutrino mixing using atmospheric neutrinos in Super-Kamiokande Physical Review D - Particles, Fields, Gravitation and Cosmology. 91. DOI: 10.1103/PhysRevD.91.052019  0.32
2015 Abe K, Haga Y, Hayato Y, Ikeda M, Iyogi K, Kameda J, Kishimoto Y, Miura M, Moriyama S, Nakahata M, Nakano Y, Nakayama S, Sekiya H, Shiozawa M, Suzuki Y, ... Takeda A, et al. Test of Lorentz invariance with atmospheric neutrinos Physical Review D - Particles, Fields, Gravitation and Cosmology. 91. DOI: 10.1103/PhysRevD.91.052003  0.32
2015 Suzuki M, Fujise Y, Tsuchiya Y, Tamano H, Takeda A. Excess influx of Zn2+ into dentate granule cells affects object recognition memory via attenuated LTP Neurochemistry International. DOI: 10.1016/j.neuint.2015.05.006  0.44
2015 Zhang H, Abe K, Hayato Y, Iyogi K, Kameda J, Kishimoto Y, Miura M, Moriyama S, Nakahata M, Nakano Y, Nakayama S, Sekiya H, Shiozawa M, Suzuki Y, Takeda A, et al. Supernova Relic Neutrino search with neutron tagging at Super-Kamiokande-IV Astroparticle Physics. 60: 41-46. DOI: 10.1016/j.astropartphys.2014.05.004  0.32
2014 Takeda A, Nakamura M, Fujii H, Uematsu C, Minamino T, Adlard PA, Bush AI, Tamano H. Amyloid β-mediated Zn2+ influx into dentate granule cells transiently induces a short-term cognitive deficit. Plos One. 9: e115923. PMID 25536033 DOI: 10.1371/journal.pone.0115923  0.88
2014 Shoji Y, Nishio Y, Baba T, Uchiyama M, Yokoi K, Ishioka T, Hosokai Y, Hirayama K, Fukuda H, Aoki M, Hasegawa T, Takeda A, Mori E. Neural substrates of cognitive subtypes in Parkinson's disease: a 3-year longitudinal study. Plos One. 9: e110547. PMID 25330390 DOI: 10.1371/journal.pone.0110547  1
2014 Abe K, Hayato Y, Iida T, Iyogi K, Kameda J, Koshio Y, Kozuma Y, Marti L, Miura M, Moriyama S, Nakahata M, Nakayama S, Obayashi Y, Sekiya H, Shiozawa M, ... ... Takeda A, et al. Search for nucleon decay via n→ν[over ¯]π0 and p→ν[over ¯]π+ in Super-Kamiokande. Physical Review Letters. 113: 121802. PMID 25279622 DOI: 10.1103/PhysRevLett.113.121802  0.32
2014 Takhistov V, Abe K, Haga Y, Hayato Y, Ikeda M, Iyogi K, Kameda J, Kishimoto Y, Miura M, Moriyama S, Nakahata M, Nakano Y, Nakayama S, Sekiya H, Shiozawa M, ... ... Takeda A, et al. Search for trilepton nucleon decay via p→e+νν and p→μ+νν in the Super-Kamiokande experiment. Physical Review Letters. 113: 101801. PMID 25238348 DOI: 10.1103/PhysRevLett.113.101801  0.32
2014 Miura E, Hasegawa T, Konno M, Suzuki M, Sugeno N, Fujikake N, Geisler S, Tabuchi M, Oshima R, Kikuchi A, Baba T, Wada K, Nagai Y, Takeda A, Aoki M. VPS35 dysfunction impairs lysosomal degradation of α-synuclein and exacerbates neurotoxicity in a Drosophila model of Parkinson's disease. Neurobiology of Disease. 71: 1-13. PMID 25107340 DOI: 10.1016/j.nbd.2014.07.014  0.32
2014 Takeda A, Tamano H, Ogawa T, Takada S, Nakamura M, Fujii H, Ando M. Intracellular Zn(2+) signaling in the dentate gyrus is required for object recognition memory. Hippocampus. 24: 1404-12. PMID 24978470 DOI: 10.1002/hipo.22322  0.88
2014 Abe K, Adam J, Aihara H, Akiri T, Andreopoulos C, Aoki S, Ariga A, Ariga T, Assylbekov S, Autiero D, Barbi M, Barker GJ, Barr G, Bass M, Batkiewicz M, ... ... Takeda A, et al. Precise measurement of the neutrino mixing parameter θ23 from muon neutrino disappearance in an off-axis beam. Physical Review Letters. 112: 181801. PMID 24856687 DOI: 10.1103/PhysRevLett.112.181801  0.32
2014 Sugeno N, Hasegawa T, Tanaka N, Fukuda M, Wakabayashi K, Oshima R, Konno M, Miura E, Kikuchi A, Baba T, Anan T, Nakao M, Geisler S, Aoki M, Takeda A. Lys-63-linked ubiquitination by E3 ubiquitin ligase Nedd4-1 facilitates endosomal sequestration of internalized α-synuclein. The Journal of Biological Chemistry. 289: 18137-51. PMID 24831002 DOI: 10.1074/jbc.M113.529461  1
2014 Kikuchi A, Baba T, Hasegawa T, Sugeno N, Konno M, Miura E, Oshima R, Aoki M, Takeda A. Improvement of freezing of gait in patients with Parkinson's disease by imagining bicycling. Case Reports in Neurology. 6: 92-5. PMID 24761145 DOI: 10.1159/000362119  1
2014 Stankovic I, Krismer F, Jesic A, Antonini A, Benke T, Brown RG, Burn DJ, Holton JL, Kaufmann H, Kostic VS, Ling H, Meissner WG, Poewe W, Semnic M, Seppi K, ... Takeda A, et al. Cognitive impairment in multiple system atrophy: a position statement by the Neuropsychology Task Force of the MDS Multiple System Atrophy (MODIMSA) study group. Movement Disorders : Official Journal of the Movement Disorder Society. 29: 857-67. PMID 24753321 DOI: 10.1002/mds.25880  1
2014 Litos M, Abe K, Hayato Y, Iida T, Ikeda M, Iyogi K, Kameda J, Kobayashi K, Koshio Y, Kozuma Y, Miura M, Moriyama S, Nakahata M, Nakayama S, Obayashi Y, ... ... Takeda A, et al. Search for dinucleon decay into kaons in Super-Kamiokande. Physical Review Letters. 112: 131803. PMID 24745406 DOI: 10.1103/PhysRevLett.112.131803  0.32
2014 Takeda A, Fujii H, Minamino T, Tamano H. Intracellular Zn(2+) signaling in cognition. Journal of Neuroscience Research. 92: 819-24. PMID 24723300 DOI: 10.1002/jnr.23385  0.44
2014 Masahata K, Umemoto E, Kayama H, Kotani M, Nakamura S, Kurakawa T, Kikuta J, Gotoh K, Motooka D, Sato S, Higuchi T, Baba Y, Kurosaki T, Kinoshita M, Shimada Y, ... ... Takeda A, et al. Generation of colonic IgA-secreting cells in the caecal patch. Nature Communications. 5: 3704. PMID 24718324 DOI: 10.1038/ncomms4704  0.36
2014 Renshaw A, Abe K, Hayato Y, Iyogi K, Kameda J, Kishimoto Y, Miura M, Moriyama S, Nakahata M, Nakano Y, Nakayama S, Sekiya H, Shiozawa M, Suzuki Y, Takeda A, et al. First indication of terrestrial matter effects on solar neutrino oscillation. Physical Review Letters. 112: 091805. PMID 24655245 DOI: 10.1103/PhysRevLett.112.091805  0.32
2014 Takeda A, Baba T, Kikuchi A, Hasegawa T, Sugeno N, Konno M, Miura E, Mori E. Olfactory dysfunction and dementia in Parkinson's disease. Journal of Parkinson's Disease. 4: 181-7. PMID 24625830 DOI: 10.3233/JPD-130277  0.32
2014 Tamano H, Fukura K, Suzuki M, Sakamoto K, Yokogoshi H, Takeda A. Advantageous effect of theanine intake on cognition. Nutritional Neuroscience. 17: 279-83. PMID 24621060 DOI: 10.1179/1476830513Y.0000000094  0.44
2014 Takeda A, Tamano H. Cognitive decline due to excess synaptic Zn(2+) signaling in the hippocampus. Frontiers in Aging Neuroscience. 6: 26. PMID 24578691 DOI: 10.3389/fnagi.2014.00026  0.44
2014 Ferraro LH, Takeda A, dos Reis Falcão LF, Rezende AH, Sadatsune EJ, Tardelli MA. Determination of the minimum effective volume of 0.5% bupivacaine for ultrasound-guided axillary brachial plexus block. Brazilian Journal of Anesthesiology (Elsevier). 64: 49-53. PMID 24565388 DOI: 10.1016/j.bjane.2013.03.014  0.01
2014 Abe K, Hayato Y, Iida T, Iyogi K, Kameda J, Koshio Y, Kozuma Y, Marti L, Miura M, Moriyama S, Nakahata M, Nakayama S, Obayashi Y, Sekiya H, Shiozawa M, ... ... Takeda A, et al. Search for nucleon decay via n → ν ¯ π0 and p → ν ¯ π+ in super-kamiokande Physical Review Letters. 113. DOI: 10.1103/PhysRevLett.113.121802  0.32
2014 Takhistov V, Abe K, Haga Y, Hayato Y, Ikeda M, Iyogi K, Kameda J, Kishimoto Y, Miura M, Moriyama S, Nakahata M, Nakano Y, Nakayama S, Sekiya H, Shiozawa M, ... ... Takeda A, et al. Search for trilepton nucleon decay via p →e+νν and p →μ+νν in the Super-Kamiokande experiment Physical Review Letters. 113. DOI: 10.1103/PhysRevLett.113.101801  0.32
2014 Abe K, Hayato Y, Iyogi K, Kameda J, Miura M, Moriyama S, Nakahata M, Nakayama S, Wendell RA, Sekiya H, Shiozawa M, Suzuki Y, Takeda A, Takenaga Y, Ueno K, et al. Search for proton decay via p →νK+ using 260kiloton·year data of Super-Kamiokande search for proton decay via p →νK+ ... K. Abe et al. Physical Review D - Particles, Fields, Gravitation and Cosmology. 90. DOI: 10.1103/PhysRevD.90.072005  0.32
2014 Abe K, Hayato Y, Iida T, Iyogi K, Kameda J, Kishimoto Y, Koshio Y, Marti L, Miura M, Moriyama S, Nakahata M, Nakano Y, Nakayama S, Obayashi Y, Sekiya H, ... ... Takeda A, et al. Calibration of the Super-Kamiokande detector Nuclear Instruments and Methods in Physics Research, Section a: Accelerators, Spectrometers, Detectors and Associated Equipment. 737: 253-272. DOI: 10.1016/j.nima.2013.11.081  0.32
2013 da Silva HC, Almeida Cdos S, Brandão JC, Nogueira e Silva CA, de Lorenzo ME, Ferreira CB, Resende AH, Barreira SR, de Almeida PA, Ferraro LH, Takeda A, de Oliveira KF, Lelis TG, Hortense A, Perez MV, et al. Malignant hyperthermia in Brazil: analysis of hotline activity in 2009. Brazilian Journal of Anesthesiology (Elsevier). 63: 13-9. PMID 24565087 DOI: 10.1016/j.bjane.2012.03.001  0.01
2013 Minami A, Matsushita H, Horii Y, Ieno D, Matsuda Y, Saito M, Kanazawa H, Ohyama Y, Wakatsuki A, Takeda A, Hidari KI, Sabaratnam V, Suzuki T. Improvement of depression-like behavior and memory impairment with the ethanol extract of Pleurotus eryngii in ovariectomized rats. Biological & Pharmaceutical Bulletin. 36: 1990-5. PMID 24292057 DOI: DN/JST.JSTAGE/bpb/b13-00657  0.36
2013 Takeda A. [Treatment & management guidelines 2011 for Parkinson disease]. Rinshō Shinkeigaku = Clinical Neurology. 53: 1346-7. PMID 24291983 DOI: DN/JST.JSTAGE/clinicalneurol/53.1346  1
2013 Takeda A, Iida M, Ando M, Nakamura M, Tamano H, Oku N. Enhanced susceptibility to spontaneous seizures of noda epileptic rats by loss of synaptic zn(2+). Plos One. 8: e71372. PMID 23951148 DOI: 10.1371/journal.pone.0071372  0.88
2013 Abe K, Hayato Y, Iida T, Iyogi K, Kameda J, Koshio Y, Kozuma Y, Marti L, Miura M, Moriyama S, Nakahata M, Nakayama S, Obayashi Y, Sekiya H, Shiozawa M, ... ... Takeda A, et al. Evidence for the appearance of atmospheric tau neutrinos in super-Kamiokande. Physical Review Letters. 110: 181802. PMID 23683190 DOI: 10.1103/PhysRevLett.110.181802  0.32
2013 Eriguchi T, Takeda A, Oku Y, Ishikura S, Kimura T, Ozawa S, Nakashima T, Matsuo Y, Nakamura M, Matsumoto Y, Yamazaki S, Sanuki N, Ito Y. Multi-institutional comparison of treatment planning using stereotactic ablative body radiotherapy for hepatocellular carcinoma - benchmark for a prospective multi-institutional study. Radiation Oncology (London, England). 8: 113. PMID 23641879 DOI: 10.1186/1748-717X-8-113  0.88
2013 Tano O, Kaneko K, Kikuchi A, Hasegawa T, Takeda A, Aoki M. [Dopaminergic drug-induced jaw-opening dystonia in a patient with progressive supranuclear palsy]. Rinshō Shinkeigaku = Clinical Neurology. 53: 308-11. PMID 23603547 DOI: DN/JST.JSTAGE/clinicalneurol/53.308  0.32
2013 Takeda A. [Severe olfactory dysfunction is a predictor of dementia with Parkinson's disease]. Rinshō Shinkeigaku = Clinical Neurology. 53: 91-7. PMID 23470887 DOI: DN/JST.JSTAGE/clinicalneurol/53.91  1
2013 Tamano H, Fukura K, Suzuki M, Sakamoto K, Yokogoshi H, Takeda A. Preventive effect of theanine intake on stress-induced impairments of hippocamapal long-term potentiation and recognition memory. Brain Research Bulletin. 95: 1-6. PMID 23458739 DOI: 10.1016/j.brainresbull.2013.02.005  0.44
2013 Kikuchi A, Baba T, Hasegawa T, Kobayashi M, Sugeno N, Konno M, Miura E, Hosokai Y, Ishioka T, Nishio Y, Hirayama K, Suzuki K, Aoki M, Takahashi S, Fukuda H, ... ... Takeda A, et al. Hypometabolism in the supplementary and anterior cingulate cortices is related to dysphagia in Parkinson's disease: a cross-sectional and 3-year longitudinal cohort study. Bmj Open. 3. PMID 23457325 DOI: 10.1136/bmjopen-2012-002249  1
2013 Takeda A, Nakamura M, Fujii H, Tamano H. Synaptic Zn(2+) homeostasis and its significance. Metallomics : Integrated Biometal Science. 5: 417-23. PMID 23423555 DOI: 10.1039/c3mt20269k  0.88
2013 Kaneko K, Tano O, Kikuchi A, Hasegawa T, Tateyama M, Yoshioka M, Saito H, Watanabe O, Takeda A, Aoki M. Anti-voltage-gated potassium channel antibody is associated with chronic autonomic and sensory neuropathy. Journal of Neurology. 260: 315-7. PMID 23117295 DOI: 10.1007/s00415-012-6730-0  0.36
2012 Konno M, Hasegawa T, Baba T, Miura E, Sugeno N, Kikuchi A, Fiesel FC, Sasaki T, Aoki M, Itoyama Y, Takeda A. Suppression of dynamin GTPase decreases α-synuclein uptake by neuronal and oligodendroglial cells: a potent therapeutic target for synucleinopathy. Molecular Neurodegeneration. 7: 38. PMID 22892036 DOI: 10.1186/1750-1326-7-38  0.48
2012 Hiraoka K, Okamura N, Funaki Y, Hayashi A, Tashiro M, Hisanaga K, Fujii T, Takeda A, Yanai K, Iwata R, Mori E. Cholinergic deficit and response to donepezil therapy in Parkinson's disease with dementia. European Neurology. 68: 137-43. PMID 22832236 DOI: 10.1159/000338774  1
2012 Sawada Y, Nishio Y, Suzuki K, Hirayama K, Takeda A, Hosokai Y, Ishioka T, Itoyama Y, Takahashi S, Fukuda H, Mori E. Attentional set-shifting deficit in Parkinson's disease is associated with prefrontal dysfunction: an FDG-PET study. Plos One. 7: e38498. PMID 22685575 DOI: 10.1371/journal.pone.0038498  1
2012 Takeda A, Tamano H. Proposed glucocorticoid-mediated zinc signaling in the hippocampus. Metallomics : Integrated Biometal Science. 4: 614-8. PMID 22610492 DOI: 10.1039/c2mt20018j  0.44
2012 Toyoshima KE, Asakawa K, Ishibashi N, Toki H, Ogawa M, Hasegawa T, Irié T, Tachikawa T, Sato A, Takeda A, Tsuji T. Fully functional hair follicle regeneration through the rearrangement of stem cells and their niches. Nature Communications. 3: 784. PMID 22510689 DOI: 10.1038/ncomms1784  0.32
2012 Baba T, Takeda A. [Recent advances in imaging in Parkinson disease]. Brain and Nerve = Shinkei KenkyÅ« No Shinpo. 64: 423-32. PMID 22481515  1
2012 Takeda A, Iwaki H, Ide K, Tamano H, Oku N. Therapeutic effect of Yokukansan on social isolation-induced aggressive behavior of zinc-deficient and pair-fed mice. Brain Research Bulletin. 87: 551-5. PMID 22373913 DOI: 10.1016/j.brainresbull.2012.02.003  0.44
2012 Takeda A, Suzuki M, Tamano H, Takada S, Ide K, Oku N. Involvement of glucocorticoid-mediated Zn2+ signaling in attenuation of hippocampal CA1 LTP by acute stress. Neurochemistry International. 60: 394-9. PMID 22306774 DOI: 10.1016/j.neuint.2012.01.021  0.44
2012 Baba T, Kikuchi A, Hirayama K, Nishio Y, Hosokai Y, Kanno S, Hasegawa T, Sugeno N, Konno M, Suzuki K, Takahashi S, Fukuda H, Aoki M, Itoyama Y, Mori E, ... Takeda A, et al. Severe olfactory dysfunction is a prodromal symptom of dementia associated with Parkinson's disease: a 3 year longitudinal study. Brain : a Journal of Neurology. 135: 161-9. PMID 22287381 DOI: 10.1093/brain/awr321  1
2012 Takeda A, Tamano H, Ogawa T, Takada S, Ando M, Oku N, Watanabe M. Significance of serum glucocorticoid and chelatable zinc in depression and cognition in zinc deficiency. Behavioural Brain Research. 226: 259-64. PMID 21946308 DOI: 10.1016/j.bbr.2011.09.026  0.44
2012 Takeda A, Tamano H, Suzuki M, Sakamoto K, Oku N, Yokogoshi H. Unique induction of CA1 LTP components after intake of theanine, an amino acid in tea leaves and its effect on stress response. Cellular and Molecular Neurobiology. 32: 41-8. PMID 21739364 DOI: 10.1007/s10571-011-9732-z  0.44
2011 Takeda A. [Parkinson's disease with dementia (PDD)]. Nihon Rinsho. Japanese Journal of Clinical Medicine. 69: 350-5. PMID 22755212  1
2011 Abe K, Hayato Y, Iida T, Ikeda M, Iyogi K, Kameda J, Koshio Y, Kozuma Y, Miura M, Moriyama S, Nakahata M, Nakayama S, Obayashi Y, Sekiya H, Shiozawa M, ... ... Takeda A, et al. Search for differences in oscillation parameters for atmospheric neutrinos and antineutrinos at Super-Kamiokande. Physical Review Letters. 107: 241801. PMID 22242990 DOI: 10.1103/PhysRevLett.107.241801  0.32
2011 Hasegawa T, Konno M, Baba T, Sugeno N, Kikuchi A, Kobayashi M, Miura E, Tanaka N, Tamai K, Furukawa K, Arai H, Mori F, Wakabayashi K, Aoki M, Itoyama Y, ... Takeda A, et al. The AAA-ATPase VPS4 regulates extracellular secretion and lysosomal targeting of α-synuclein. Plos One. 6: e29460. PMID 22216284 DOI: 10.1371/journal.pone.0029460  0.48
2011 Takeda A, Takada S, Nakamura M, Suzuki M, Tamano H, Ando M, Oku N. Transient increase in Zn2+ in hippocampal CA1 pyramidal neurons causes reversible memory deficit. Plos One. 6: e28615. PMID 22163318 DOI: 10.1371/journal.pone.0028615  0.88
2011 Kikuchi A, Baba T, Hasegawa T, Sugeno N, Konno M, Takeda A. Differentiating Parkinson's disease from multiple system atrophy by [123I] meta-iodobenzylguanidine myocardial scintigraphy and olfactory test. Parkinsonism & Related Disorders. 17: 698-700. PMID 21840242 DOI: 10.1016/j.parkreldis.2011.07.011  0.32
2011 Takeda A, Sakamoto K, Tamano H, Fukura K, Inui N, Suh SW, Won SJ, Yokogoshi H. Facilitated neurogenesis in the developing hippocampus after intake of theanine, an amino acid in tea leaves, and object recognition memory. Cellular and Molecular Neurobiology. 31: 1079-88. PMID 21604187 DOI: 10.1007/s10571-011-9707-0  0.44
2011 Kanno S, Abe N, Saito M, Takagi M, Nishio Y, Hayashi A, Uchiyama M, Hanaki R, Kikuchi H, Hiraoka K, Yamasaki H, Iizuka O, Takeda A, Itoyama Y, Takahashi S, et al. White matter involvement in idiopathic normal pressure hydrocephalus: a voxel-based diffusion tensor imaging study. Journal of Neurology. 258: 1949-57. PMID 21512742 DOI: 10.1007/s00415-011-6038-5  0.36
2011 Tamano H, Takeda A. Dynamic action of neurometals at the synapse. Metallomics : Integrated Biometal Science. 3: 656-61. PMID 21409223 DOI: 10.1039/c1mt00008j  0.44
2011 Ishioka T, Hirayama K, Hosokai Y, Takeda A, Suzuki K, Nishio Y, Sawada Y, Takahashi S, Fukuda H, Itoyama Y, Mori E. Illusory misidentifications and cortical hypometabolism in Parkinson's disease. Movement Disorders : Official Journal of the Movement Disorder Society. 26: 837-43. PMID 21370270 DOI: 10.1002/mds.23576  0.36
2011 Baba T, Takeda A, Kikuchi A, Nishio Y, Hosokai Y, Hirayama K, Hasegawa T, Sugeno N, Suzuki K, Mori E, Takahashi S, Fukuda H, Itoyama Y. Association of olfactory dysfunction and brain. Metabolism in Parkinson's disease. Movement Disorders : Official Journal of the Movement Disorder Society. 26: 621-8. PMID 21284041 DOI: 10.1002/mds.23602  0.48
2010 Kikuchi A, Takeda A, Itoyama Y. Transient cytotoxic edema in the splenium of the corpus callosum. Internal Medicine (Tokyo, Japan). 49: 2711. PMID 21173548 DOI: JST.JSTAGE/internalmedicine/49.3731  0.48
2010 Takeda A, Takada S, Ando M, Itagaki K, Tamano H, Suzuki M, Iwaki H, Oku N. Impairment of recognition memory and hippocampal long-term potentiation after acute exposure to clioquinol. Neuroscience. 171: 443-50. PMID 20849933 DOI: 10.1016/j.neuroscience.2010.09.017  0.44
2010 Hasegawa T, Baba T, Kobayashi M, Konno M, Sugeno N, Kikuchi A, Itoyama Y, Takeda A. Role of TPPP/p25 on α-synuclein-mediated oligodendroglial degeneration and the protective effect of SIRT2 inhibition in a cellular model of multiple system atrophy. Neurochemistry International. 57: 857-66. PMID 20849899 DOI: 10.1016/j.neuint.2010.09.002  0.48
2010 Tamano H, Kan F, Oku N, Takeda A. Ameliorative effect of Yokukansan on social isolation-induced aggressive behavior of zinc-deficient young mice. Brain Research Bulletin. 83: 351-5. PMID 20813168 DOI: 10.1016/j.brainresbull.2010.08.013  0.44
2010 Takeda A, Suzuki M, Tamano H, Ando M, Oku N. Differential effects of zinc influx via AMPA/kainate receptor activation on subsequent induction of hippocampal CA1 LTP components. Brain Research. 1354: 188-95. PMID 20654593 DOI: 10.1016/j.brainres.2010.07.039  0.44
2010 Takeda A, Tamano H. Zinc signaling through glucocorticoid and glutamate signaling in stressful circumstances. Journal of Neuroscience Research. 88: 3002-10. PMID 20568287 DOI: 10.1002/jnr.22456  0.44
2010 Kikuchi A, Takeda A, Okamura N, Tashiro M, Hasegawa T, Furumoto S, Kobayashi M, Sugeno N, Baba T, Miki Y, Mori F, Wakabayashi K, Funaki Y, Iwata R, Takahashi S, et al. In vivo visualization of alpha-synuclein deposition by carbon-11-labelled 2-[2-(2-dimethylaminothiazol-5-yl)ethenyl]-6-[2-(fluoro)ethoxy]benzoxazole positron emission tomography in multiple system atrophy. Brain : a Journal of Neurology. 133: 1772-8. PMID 20430832 DOI: 10.1093/brain/awq091  1
2010 Watanabe M, Tamano H, Kikuchi T, Takeda A. Susceptibility to stress in young rats after 2-week zinc deprivation. Neurochemistry International. 56: 410-6. PMID 19931332 DOI: 10.1016/j.neuint.2009.11.014  0.44
2010 Takeda A, Saito N, Baba T, Kikuchi A, Sugeno N, Kobayashi M, Hasegawa T, Itoyama Y. Functional imaging studies of hyposmia in Parkinson's disease. Journal of the Neurological Sciences. 289: 36-9. PMID 19720385 DOI: 10.1016/j.jns.2009.08.041  1
2009 Takeda A, Baba T, Kikuchi A, Sugeno N, Hasegawa T, Itoyama Y, Ishioka T, Hirayama K, Mori E. [Pathophysiological process underlying Parkinson's disease: motor & non-motor symptoms]. Rinshō Shinkeigaku = Clinical Neurology. 49: 888-9. PMID 20030239  0.48
2009 Takeda A, Tamano H. Insight into zinc signaling from dietary zinc deficiency. Brain Research Reviews. 62: 33-44. PMID 19747942 DOI: 10.1016/j.brainresrev.2009.09.003  0.44
2009 Su B, Liu H, Wang X, Chen SG, Siedlak SL, Kondo E, Choi R, Takeda A, Castellani RJ, Perry G, Smith MA, Zhu X, Lee HG. Ectopic localization of FOXO3a protein in Lewy bodies in Lewy body dementia and Parkinson's disease. Molecular Neurodegeneration. 4: 32. PMID 19627592 DOI: 10.1186/1750-1326-4-32  1
2008 Castellani RJ, Nunomura A, Rolston RK, Moreira PI, Takeda A, Perry G, Smith MA. Sublethal RNA oxidation as a mechanism for neurodegenerative disease. International Journal of Molecular Sciences. 9: 789-806. PMID 19325784 DOI: 10.3390/ijms9050789  1
2008 Moreira PI, Nunomura A, Nakamura M, Takeda A, Shenk JC, Aliev G, Smith MA, Perry G. Nucleic acid oxidation in Alzheimer disease. Free Radical Biology & Medicine. 44: 1493-505. PMID 18258207 DOI: 10.1016/j.freeradbiomed.2008.01.002  1
2007 Nunomura A, Moreira PI, Takeda A, Smith MA, Perry G. Oxidative RNA damage and neurodegeneration. Current Medicinal Chemistry. 14: 2968-75. PMID 18220733 DOI: 10.2174/092986707782794078  1
2006 Nunomura A, Honda K, Takeda A, Hirai K, Zhu X, Smith MA, Perry G. Oxidative damage to RNA in neurodegenerative diseases. Journal of Biomedicine & Biotechnology. 2006: 82323. PMID 17047315 DOI: 10.1155/JBB/2006/82323  1
2006 Lee HG, Zhu X, Takeda A, Perry G, Smith MA. Emerging evidence for the neuroprotective role of alpha-synuclein. Experimental Neurology. 200: 1-7. PMID 16780837 DOI: 10.1016/j.expneurol.2006.04.024  1
2006 Hasegawa T, Matsuzaki-Kobayashi M, Takeda A, Sugeno N, Kikuchi A, Furukawa K, Perry G, Smith MA, Itoyama Y. Alpha-synuclein facilitates the toxicity of oxidized catechol metabolites: implications for selective neurodegeneration in Parkinson's disease. Febs Letters. 580: 2147-52. PMID 16567160 DOI: 10.1016/j.febslet.2006.03.018  1
2005 Dwyer BE, Takeda A, Zhu X, Perry G, Smith MA. Ferric cycle activity and Alzheimer disease. Current Neurovascular Research. 2: 261-7. PMID 16181119 DOI: 10.2174/1567202054368371  1
2005 Lee HG, Perry G, Moreira PI, Garrett MR, Liu Q, Zhu X, Takeda A, Nunomura A, Smith MA. Tau phosphorylation in Alzheimer's disease: pathogen or protector? Trends in Molecular Medicine. 11: 164-9. PMID 15823754 DOI: 10.1016/j.molmed.2005.02.008  1
2005 Liu Q, Smith MA, Avilá J, DeBernardis J, Kansal M, Takeda A, Zhu X, Nunomura A, Honda K, Moreira PI, Oliveira CR, Santos MS, Shimohama S, Aliev G, de la Torre J, et al. Alzheimer-specific epitopes of tau represent lipid peroxidation-induced conformations. Free Radical Biology & Medicine. 38: 746-54. PMID 15721985 DOI: 10.1016/j.freeradbiomed.2004.11.005  1
2005 Liu Q, Lee HG, Honda K, Siedlak SL, Harris PL, Cash AD, Zhu X, Avila J, Nunomura A, Takeda A, Smith MA, Perry G. Tau modifiers as therapeutic targets for Alzheimer's disease. Biochimica Et Biophysica Acta. 1739: 211-5. PMID 15615639 DOI: 10.1016/j.bbadis.2004.06.021  1
2004 Nunomura A, Chiba S, Lippa CF, Cras P, Kalaria RN, Takeda A, Honda K, Smith MA, Perry G. Neuronal RNA oxidation is a prominent feature of familial Alzheimer's disease. Neurobiology of Disease. 17: 108-13. PMID 15350971 DOI: 10.1016/j.nbd.2004.06.003  1
2004 Takeda A, Itoyama Y, Kimpara T, Zhu X, Avila J, Dwyer BE, Perry G, Smith MA. Heme catabolism and heme oxygenase in neurodegenerative disease. Antioxidants & Redox Signaling. 6: 888-94. PMID 15345149 DOI: 10.1089/ars.2004.6.888  1
2004 Lee HG, Casadesus G, Zhu X, Takeda A, Perry G, Smith MA. Challenging the amyloid cascade hypothesis: senile plaques and amyloid-beta as protective adaptations to Alzheimer disease. Annals of the New York Academy of Sciences. 1019: 1-4. PMID 15246983 DOI: 10.1196/annals.1297.001  1
2004 Hasegawa T, Matsuzaki M, Takeda A, Kikuchi A, Akita H, Perry G, Smith MA, Itoyama Y. Accelerated alpha-synuclein aggregation after differentiation of SH-SY5Y neuroblastoma cells. Brain Research. 1013: 51-9. PMID 15196967 DOI: 10.1016/j.brainres.2004.04.018  1
2003 Tateyama M, Takeda A, Onodera Y, Matsuzaki M, Hasegawa T, Nunomura A, Hirai K, Perry G, Smith MA, Itoyama Y. Oxidative stress and predominant Abeta42(43) deposition in myopathies with rimmed vacuoles. Acta Neuropathologica. 105: 581-5. PMID 12734664 DOI: 10.1007/s00401-003-0685-2  1
2002 Perry G, Nunomura A, Hirai K, Zhu X, Pérez M, Avila J, Castellani RJ, Atwood CS, Aliev G, Sayre LM, Takeda A, Smith MA. Is oxidative damage the fundamental pathogenic mechanism of Alzheimer's and other neurodegenerative diseases? Free Radical Biology & Medicine. 33: 1475-9. PMID 12446204 DOI: 10.1016/S0891-5849(02)01113-9  1
2002 Nunomura A, Chiba S, Kosaka K, Takeda A, Castellani RJ, Smith MA, Perry G. Neuronal RNA oxidation is a prominent feature of dementia with Lewy bodies. Neuroreport. 13: 2035-9. PMID 12438921 DOI: 10.1097/00001756-200211150-00009  1
2002 Castellani R, Hirai K, Aliev G, Drew KL, Nunomura A, Takeda A, Cash AD, Obrenovich ME, Perry G, Smith MA. Role of mitochondrial dysfunction in Alzheimer's disease. Journal of Neuroscience Research. 70: 357-60. PMID 12391597 DOI: 10.1002/jnr.10389  1
2002 Kikuchi A, Takeda A, Onodera H, Kimpara T, Hisanaga K, Sato N, Nunomura A, Castellani RJ, Perry G, Smith MA, Itoyama Y. Systemic increase of oxidative nucleic acid damage in Parkinson's disease and multiple system atrophy. Neurobiology of Disease. 9: 244-8. PMID 11895375 DOI: 10.1006/nbdi.2002.0466  1
2002 Smith MA, Drew KL, Nunomura A, Takeda A, Hirai K, Zhu X, Atwood CS, Raina AK, Rottkamp CA, Sayre LM, Friedland RP, Perry G. Amyloid-beta, tau alterations and mitochondrial dysfunction in Alzheimer disease: the chickens or the eggs? Neurochemistry International. 40: 527-31. PMID 11850109 DOI: 10.1016/S0197-0186(01)00123-1  1
2001 Zhu X, Rottkamp CA, Hartzler A, Sun Z, Takeda A, Boux H, Shimohama S, Perry G, Smith MA. Activation of MKK6, an upstream activator of p38, in Alzheimer's disease. Journal of Neurochemistry. 79: 311-8. PMID 11677259 DOI: 10.1046/j.1471-4159.2001.00597.x  1
2001 Zhu X, Castellani RJ, Takeda A, Nunomura A, Atwood CS, Perry G, Smith MA. Differential activation of neuronal ERK, JNK/SAPK and p38 in Alzheimer disease: the 'two hit' hypothesis. Mechanisms of Ageing and Development. 123: 39-46. PMID 11640950 DOI: 10.1016/S0047-6374(01)00342-6  1
2001 Nunomura A, Perry G, Aliev G, Hirai K, Takeda A, Balraj EK, Jones PK, Ghanbari H, Wataya T, Shimohama S, Chiba S, Atwood CS, Petersen RB, Smith MA. Oxidative damage is the earliest event in Alzheimer disease. Journal of Neuropathology and Experimental Neurology. 60: 759-67. PMID 11487050  1
2000 Smith MA, Nunomura A, Zhu X, Takeda A, Perry G. Metabolic, metallic, and mitotic sources of oxidative stress in Alzheimer disease. Antioxidants & Redox Signaling. 2: 413-20. PMID 11229355 DOI: 10.1089/15230860050192198  1
2000 Zhu X, Rottkamp CA, Boux H, Takeda A, Perry G, Smith MA. Activation of p38 kinase links tau phosphorylation, oxidative stress, and cell cycle-related events in Alzheimer disease. Journal of Neuropathology and Experimental Neurology. 59: 880-8. PMID 11079778  1
2000 Takeda A, Smith MA, Avilá J, Nunomura A, Siedlak SL, Zhu X, Perry G, Sayre LM. In Alzheimer's disease, heme oxygenase is coincident with Alz50, an epitope of tau induced by 4-hydroxy-2-nonenal modification. Journal of Neurochemistry. 75: 1234-41. PMID 10936206 DOI: 10.1046/j.1471-4159.2000.0751234.x  1
2000 Raina AK, Zhu X, Rottkamp CA, Monteiro M, Takeda A, Smith MA. Cyclin' toward dementia: cell cycle abnormalities and abortive oncogenesis in Alzheimer disease. Journal of Neuroscience Research. 61: 128-33. PMID 10878584 DOI: 10.1002/1097-4547(20000715)61:2<128::AID-JNR2>3.0.CO;2-H  1
2000 Zhu X, Raina AK, Boux H, Simmons ZL, Takeda A, Smith MA. Activation of oncogenic pathways in degenerating neurons in Alzheimer disease. International Journal of Developmental Neuroscience : the Official Journal of the International Society For Developmental Neuroscience. 18: 433-7. PMID 10817927 DOI: 10.1016/S0736-5748(00)00010-1  1
2000 Perry G, Nunomura A, Hirai K, Takeda A, Aliev G, Smith MA. Oxidative damage in Alzheimer's disease: the metabolic dimension. International Journal of Developmental Neuroscience : the Official Journal of the International Society For Developmental Neuroscience. 18: 417-21. PMID 10817925 DOI: 10.1016/S0736-5748(00)00006-X  1
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