| Year |
Citation |
Score |
| 2021 |
Chang JC, Go S, Gilglioni EH, Duijst S, Panneman DM, Rodenburg RJ, Li HL, Huang HL, Levin LR, Buck J, Verhoeven AJ, Oude Elferink RPJ. Soluble adenylyl cyclase regulates the cytosolic NADH/NAD redox state and the bioenergetic switch between glycolysis and oxidative phosphorylation. Biochimica Et Biophysica Acta. Bioenergetics. 148367. PMID 33412125 DOI: 10.1016/j.bbabio.2020.148367 |
0.315 |
|
| 2018 |
Zhou D, Ota K, Nardin C, Feldman M, Widman A, Wind O, Simon A, Reilly M, Levin LR, Buck J, Wakamatsu K, Ito S, Zippin JH. Mammalian pigmentation is regulated by a distinct cAMP-dependent mechanism that controls melanosome pH. Science Signaling. 11. PMID 30401788 DOI: 10.1126/Scisignal.Aau7987 |
0.607 |
|
| 2018 |
Wiggins SV, Steegborn C, Levin LR, Buck J. Pharmacological modulation of the CO/HCO/pH-, calcium-, and ATP- sensing soluble adenylyl cyclase. Pharmacology & Therapeutics. PMID 29807057 DOI: 10.1016/J.Pharmthera.2018.05.008 |
0.369 |
|
| 2017 |
Valsecchi F, Konrad C, D'Aurelio M, Ramos-Espiritu LS, Stepanova A, Burstein SR, Galkin A, Magranè J, Starkov A, Buck J, Levin LR, Manfredi G. Distinct intracellular sAC-cAMP domains regulate ER calcium signaling and OXPHOS function. Journal of Cell Science. PMID 28864766 DOI: 10.1242/Jcs.206318 |
0.313 |
|
| 2016 |
Ramos-Espiritu L, Kleinboelting S, Navarrete FA, Alvau A, Visconti PE, Valsecchi F, Starkov A, Manfredi G, Buck H, Adura C, Zippin JH, van den Heuvel J, Glickman JF, Steegborn C, Levin LR, et al. Discovery of LRE1 as a specific and allosteric inhibitor of soluble adenylyl cyclase. Nature Chemical Biology. PMID 27547922 DOI: 10.1038/Nchembio.2151 |
0.684 |
|
| 2016 |
Ramos-Espiritu L, Diaz A, Nardin C, Saviola AJ, Shaw F, Plitt T, Yang X, Wolchok J, Pirog EC, Desman G, Sboner A, Zhang T, Xiang J, Merghoub T, Levin LR, et al. The metabolic/pH sensor soluble adenylyl cyclase is a tumor suppressor protein. Oncotarget. PMID 27323809 DOI: 10.18632/Oncotarget.10056 |
0.62 |
|
| 2014 |
Hess KC, Liu J, Manfredi G, Mühlschlegel FA, Buck J, Levin LR, Barrientos A. A mitochondrial CO2-adenylyl cyclase-cAMP signalosome controls yeast normoxic cytochrome c oxidase activity. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 28: 4369-80. PMID 25002117 DOI: 10.1096/Fj.14-252890 |
0.335 |
|
| 2014 |
Kleinboelting S, Diaz A, Moniot S, van den Heuvel J, Weyand M, Levin LR, Buck J, Steegborn C. Crystal structures of human soluble adenylyl cyclase reveal mechanisms of catalysis and of its activation through bicarbonate. Proceedings of the National Academy of Sciences of the United States of America. 111: 3727-32. PMID 24567411 DOI: 10.1073/Pnas.1322778111 |
0.318 |
|
| 2013 |
Wertheimer E, Krapf D, de la Vega-Beltran JL, Sánchez-Cárdenas C, Navarrete F, Haddad D, Escoffier J, Salicioni AM, Levin LR, Buck J, Mager J, Darszon A, Visconti PE. Compartmentalization of distinct cAMP signaling pathways in mammalian sperm. The Journal of Biological Chemistry. 288: 35307-20. PMID 24129574 DOI: 10.1074/Jbc.M113.489476 |
0.323 |
|
| 2013 |
Zippin JH, Chen Y, Straub SG, Hess KC, Diaz A, Lee D, Tso P, Holz GG, Sharp GW, Levin LR, Buck J. CO2/HCO3(-)- and calcium-regulated soluble adenylyl cyclase as a physiological ATP sensor. The Journal of Biological Chemistry. 288: 33283-91. PMID 24100033 DOI: 10.1074/Jbc.M113.510073 |
0.659 |
|
| 2013 |
Bitterman JL, Ramos-Espiritu L, Diaz A, Levin LR, Buck J. Pharmacological distinction between soluble and transmembrane adenylyl cyclases. The Journal of Pharmacology and Experimental Therapeutics. 347: 589-98. PMID 24091307 DOI: 10.1124/Jpet.113.208496 |
0.395 |
|
| 2013 |
Barott KL, Helman Y, Haramaty L, Barron ME, Hess KC, Buck J, Levin LR, Tresguerres M. High adenylyl cyclase activity and in vivo cAMP fluctuations in corals suggest central physiological role. Scientific Reports. 3: 1379. PMID 23459251 DOI: 10.1038/Srep01379 |
0.347 |
|
| 2012 |
Salazar E, Bank EM, Ramsey N, Hess KC, Deitsch KW, Levin LR, Buck J. Characterization of Plasmodium falciparum adenylyl cyclase-β and its role in erythrocytic stage parasites. Plos One. 7: e39769. PMID 22761895 DOI: 10.1371/Journal.Pone.0039769 |
0.67 |
|
| 2012 |
Topal H, Fulcher NB, Bitterman J, Salazar E, Buck J, Levin LR, Cann MJ, Wolfgang MC, Steegborn C. Crystal structure and regulation mechanisms of the CyaB adenylyl cyclase from the human pathogen Pseudomonas aeruginosa. Journal of Molecular Biology. 416: 271-86. PMID 22226839 DOI: 10.1016/J.Jmb.2011.12.045 |
0.569 |
|
| 2012 |
Chen J, Levin LR, Buck J. Role of soluble adenylyl cyclase in the heart. American Journal of Physiology. Heart and Circulatory Physiology. 302: H538-43. PMID 22058150 DOI: 10.1152/Ajpheart.00701.2011 |
0.322 |
|
| 2011 |
Ramos-Espiritu LS, Hess KC, Buck J, Levin LR. The soluble guanylyl cyclase activator YC-1 increases intracellular cGMP and cAMP via independent mechanisms in INS-1E cells. The Journal of Pharmacology and Experimental Therapeutics. 338: 925-31. PMID 21665942 DOI: 10.1124/Jpet.111.184135 |
0.363 |
|
| 2011 |
Tresguerres M, Levin LR, Buck J. Intracellular cAMP signaling by soluble adenylyl cyclase. Kidney International. 79: 1277-88. PMID 21490586 DOI: 10.1038/Ki.2011.95 |
0.373 |
|
| 2010 |
Zippin JH, Chadwick PA, Levin LR, Buck J, Magro CM. Soluble adenylyl cyclase defines a nuclear cAMP microdomain in keratinocyte hyperproliferative skin diseases. The Journal of Investigative Dermatology. 130: 1279-87. PMID 20130594 DOI: 10.1038/Jid.2009.440 |
0.602 |
|
| 2010 |
Tresguerres M, Parks SK, Salazar E, Levin LR, Goss GG, Buck J. Bicarbonate-sensing soluble adenylyl cyclase is an essential sensor for acid/base homeostasis. Proceedings of the National Academy of Sciences of the United States of America. 107: 442-7. PMID 20018667 DOI: 10.1073/Pnas.0911790107 |
0.56 |
|
| 2009 |
Acin-Perez R, Salazar E, Kamenetsky M, Buck J, Levin LR, Manfredi G. Cyclic AMP produced inside mitochondria regulates oxidative phosphorylation. Cell Metabolism. 9: 265-76. PMID 19254571 DOI: 10.1016/J.Cmet.2009.01.012 |
0.57 |
|
| 2008 |
Farrell J, Ramos L, Tresguerres M, Kamenetsky M, Levin LR, Buck J. Somatic 'soluble' adenylyl cyclase isoforms are unaffected in Sacy tm1Lex/Sacy tm1Lex 'knockout' mice. Plos One. 3: e3251. PMID 18806876 DOI: 10.1371/Journal.Pone.0003251 |
0.542 |
|
| 2008 |
Ramos LS, Zippin JH, Kamenetsky M, Buck J, Levin LR. Glucose and GLP-1 stimulate cAMP production via distinct adenylyl cyclases in INS-1E insulinoma cells. The Journal of General Physiology. 132: 329-38. PMID 18695009 DOI: 10.1083/Jcb1824Oia10 |
0.645 |
|
| 2007 |
Schmid A, Sutto Z, Nlend MC, Horvath G, Schmid N, Buck J, Levin LR, Conner GE, Fregien N, Salathe M. Soluble adenylyl cyclase is localized to cilia and contributes to ciliary beat frequency regulation via production of cAMP. The Journal of General Physiology. 130: 99-109. PMID 17591988 DOI: 10.1085/Jgp.200709784 |
0.304 |
|
| 2006 |
Wu KY, Zippin JH, Huron DR, Kamenetsky M, Hengst U, Buck J, Levin LR, Jaffrey SR. Soluble adenylyl cyclase is required for netrin-1 signaling in nerve growth cones. Nature Neuroscience. 9: 1257-64. PMID 16964251 DOI: 10.1038/Nn1767 |
0.583 |
|
| 2006 |
Kamenetsky M, Middelhaufe S, Bank EM, Levin LR, Buck J, Steegborn C. Molecular details of cAMP generation in mammalian cells: a tale of two systems. Journal of Molecular Biology. 362: 623-39. PMID 16934836 DOI: 10.1016/J.Jmb.2006.07.045 |
0.73 |
|
| 2006 |
Stessin AM, Zippin JH, Kamenetsky M, Hess KC, Buck J, Levin LR. Soluble adenylyl cyclase mediates nerve growth factor-induced activation of Rap1. The Journal of Biological Chemistry. 281: 17253-8. PMID 16627466 DOI: 10.1074/Jbc.M603500200 |
0.656 |
|
| 2005 |
Hess KC, Jones BH, Marquez B, Chen Y, Ord TS, Kamenetsky M, Miyamoto C, Zippin JH, Kopf GS, Suarez SS, Levin LR, Williams CJ, Buck J, Moss SB. The "soluble" adenylyl cyclase in sperm mediates multiple signaling events required for fertilization. Developmental Cell. 9: 249-59. PMID 16054031 DOI: 10.1016/J.Devcel.2005.06.007 |
0.64 |
|
| 2004 |
Zippin JH, Farrell J, Huron D, Kamenetsky M, Hess KC, Fischman DA, Levin LR, Buck J. Bicarbonate-responsive "soluble" adenylyl cyclase defines a nuclear cAMP microdomain. The Journal of Cell Biology. 164: 527-34. PMID 14769862 DOI: 10.1083/Jcb.200311119 |
0.717 |
|
| 2003 |
Litvin TN, Kamenetsky M, Zarifyan A, Buck J, Levin LR. Kinetic properties of "soluble" adenylyl cyclase. Synergism between calcium and bicarbonate. The Journal of Biological Chemistry. 278: 15922-6. PMID 12609998 DOI: 10.1074/Jbc.M212475200 |
0.311 |
|
| 2003 |
Zippin JH, Chen Y, Nahirney P, Kamenetsky M, Wuttke MS, Fischman DA, Levin LR, Buck J. Compartmentalization of bicarbonate-sensitive adenylyl cyclase in distinct signaling microdomains. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 17: 82-4. PMID 12475901 DOI: 10.1096/Fj.02-0598Fje |
0.66 |
|
| 2002 |
Buck J, Sinclair ML, Levin LR. Purification of soluble adenylyl cyclase. Methods in Enzymology. 345: 95-105. PMID 11665644 DOI: 10.1016/S0076-6879(02)45009-4 |
0.373 |
|
| 2001 |
Zippin JH, Levin LR, Buck J. CO(2)/HCO(3)(-)-responsive soluble adenylyl cyclase as a putative metabolic sensor. Trends in Endocrinology and Metabolism: Tem. 12: 366-70. PMID 11551811 DOI: 10.1016/S1043-2760(01)00454-4 |
0.62 |
|
| 2000 |
Chen Y, Cann MJ, Litvin TN, Iourgenko V, Sinclair ML, Levin LR, Buck J. Soluble adenylyl cyclase as an evolutionarily conserved bicarbonate sensor. Science (New York, N.Y.). 289: 625-8. PMID 10915626 DOI: 10.1126/Science.289.5479.625 |
0.362 |
|
| 2000 |
Sinclair ML, Wang XY, Mattia M, Conti M, Buck J, Wolgemuth DJ, Levin LR. Specific expression of soluble adenylyl cyclase in male germ cells. Molecular Reproduction and Development. 56: 6-11. PMID 10737962 DOI: 10.1002/(Sici)1098-2795(200005)56:1<6::Aid-Mrd2>3.0.Co;2-M |
0.327 |
|
| 2000 |
Iourgenko V, Levin LR. A calcium-inhibited Drosophila adenylyl cyclase. Biochimica Et Biophysica Acta. 1495: 125-39. PMID 10656970 DOI: 10.1016/S0167-4889(99)00155-X |
0.323 |
|
| 1999 |
Buck J, Sinclair ML, Schapal L, Cann MJ, Levin LR. Cytosolic adenylyl cyclase defines a unique signaling molecule in mammals. Proceedings of the National Academy of Sciences of the United States of America. 96: 79-84. PMID 9874775 DOI: 10.1073/Pnas.96.1.79 |
0.355 |
|
| 1995 |
Levin LR, Reed RR. Identification of functional domains of adenylyl cyclase using in vivo chimeras. The Journal of Biological Chemistry. 270: 7573-9. PMID 7706305 DOI: 10.1074/jbc.270.13.7573 |
0.368 |
|
| 1994 |
Insall R, Kuspa A, Lilly PJ, Shaulsky G, Levin LR, Loomis WF, Devreotes P. CRAC, a cytosolic protein containing a pleckstrin homology domain, is required for receptor and G protein-mediated activation of adenylyl cyclase in Dictyostelium Journal of Cell Biology. 126: 1537-1545. PMID 8089184 DOI: 10.1083/Jcb.126.6.1537 |
0.315 |
|
| 1991 |
Zoller MJ, Johnson KE, Yonemoto WM, Levin L. [51] Functional expression of mammalian adenosine cyclic monophosphate-dependent protein kinase in saccharomyces cerevisiae Methods in Enzymology. 200: 605-627. PMID 1956338 DOI: 10.1016/0076-6879(91)00175-V |
0.386 |
|
| 1988 |
Cameron S, Levin L, Zoller M, Wigler M. cAMP-independent control of sporulation, glycogen metabolism, and heat shock resistance in S. cerevisiae. Cell. 53: 555-66. PMID 2836063 DOI: 10.1016/0092-8674(88)90572-7 |
0.309 |
|
| 1987 |
Broek D, Toda T, Michaeli T, Levin L, Birchmeier C, Zoller M, Powers S, Wigler M. The S. cerevisiae CDC25 gene product regulates the RAS/adenylate cyclase pathway. Cell. 48: 789-99. PMID 3545497 DOI: 10.1016/0092-8674(87)90076-6 |
0.354 |
|
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