| Year |
Citation |
Score |
| 2024 |
Francescone R, Crawford HC, Vendramini-Costa DB. Rethinking the roles of cancer associated fibroblasts in pancreatic cancer. Cellular and Molecular Gastroenterology and Hepatology. PMID 38316215 DOI: 10.1016/j.jcmgh.2024.01.022 |
0.34 |
|
| 2023 |
Benitz S, Steep A, Nasser M, Preall J, Mahajan UM, McQuithey H, Loveless I, Davis ET, Wen HJ, Long DW, Metzler T, Zwernik S, Louw M, Rempinski D, Salas-Escabillas D, ... ... Crawford HC, et al. ROR2 regulates cellular plasticity in pancreatic neoplasia and adenocarcinoma. Biorxiv : the Preprint Server For Biology. PMID 38168289 DOI: 10.1101/2023.12.13.571566 |
0.319 |
|
| 2023 |
Radyk MD, Nelson BS, Halbrook CJ, Wood A, Lavoie B, Salvatore L, Corfas G, Colacino JA, Shah YM, Crawford HC, Lyssiotis CA. Glucose-6-phosphate dehydrogenase deficiency accelerates pancreatic acinar-to-ductal metaplasia. Biorxiv : the Preprint Server For Biology. PMID 37986898 DOI: 10.1101/2023.11.06.565895 |
0.315 |
|
| 2023 |
Roy RV, Means N, Rao G, Asfa S, Madka V, Dey A, Zhang Y, Choudhury M, Fung KM, Dhanasekaran DN, Friedman JE, Crawford HC, Rao CV, Bhattacharya R, Mukherjee P. Pancreatic Ubap2 deletion regulates glucose tolerance, inflammation, and protection from cerulein-induced pancreatitis. Cancer Letters. 216455. PMID 37865160 DOI: 10.1016/j.canlet.2023.216455 |
0.307 |
|
| 2023 |
Lu S, Kim HS, Cao Y, Bedi K, Zhao L, Narayanan IV, Magnuson B, Gu Y, Yang J, Yi Z, Babaniamansour S, Shameon S, Xu C, Paulsen MT, Qiu P, ... ... Crawford H, et al. KMT2D links TGF-β signaling to noncanonical activin pathway and regulates pancreatic cancer cell plasticity. International Journal of Cancer. PMID 37140208 DOI: 10.1002/ijc.34528 |
0.364 |
|
| 2023 |
Yi Q, Wang J, Liu T, Yao Y, Loveless I, Subedi K, Toor J, Adrianto I, Xiao H, Chen B, Crawford H, Fang D, Zhou L, Mi QS. scRNA-Seq and imaging mass cytometry analyses unveil iNKT cells-mediated anti-tumor immunity in pancreatic cancer liver metastasis. Cancer Letters. 216149. PMID 36990268 DOI: 10.1016/j.canlet.2023.216149 |
0.316 |
|
| 2023 |
Menjivar RE, Nwosu ZC, Du W, Donahue KL, Hong HS, Espinoza C, Brown K, Velez-Delgado A, Yan W, Lima F, Bischoff A, Kadiyala P, Salas-Escabillas D, Crawford HC, Bednar F, et al. Arginase 1 is a key driver of immune suppression in pancreatic cancer. Elife. 12. PMID 36727849 DOI: 10.7554/eLife.80721 |
0.727 |
|
| 2022 |
Halbrook CJ, Thurston G, Boyer S, Anaraki C, Jiménez JA, McCarthy A, Steele NG, Kerk SA, Hong HS, Lin L, Law FV, Felton C, Scipioni L, Sajjakulnukit P, Andren A, ... ... Crawford HC, et al. Differential integrated stress response and asparagine production drive symbiosis and therapy resistance of pancreatic adenocarcinoma cells. Nature Cancer. 3: 1386-1403. PMID 36411320 DOI: 10.1038/s43018-022-00463-1 |
0.307 |
|
| 2022 |
Yang J, Jin L, Kim HS, Tian F, Yi Z, Bedi K, Ljungman M, Pasca di Magliano M, Crawford H, Shi J. KDM6A Loss Recruits Tumor-Associated Neutrophils and Promotes Neutrophil Extracellular Trap Formation in Pancreatic Cancer. Cancer Research. OF1-OF14. PMID 36306422 DOI: 10.1158/0008-5472.CAN-22-0968 |
0.357 |
|
| 2022 |
Mello AM, Ngodup T, Lee Y, Donahue KL, Li J, Rao A, Carpenter ES, Crawford HC, Pasca di Magliano M, Lee KE. Hypoxia promotes an inflammatory phenotype of fibroblasts in pancreatic cancer. Oncogenesis. 11: 56. PMID 36109493 DOI: 10.1038/s41389-022-00434-2 |
0.717 |
|
| 2022 |
Scales MK, Velez-Delgado A, Steele NG, Schrader HE, Stabnick AM, Yan W, Mercado Soto NM, Nwosu ZC, Johnson C, Zhang Y, Salas-Escabillas DJ, Menjivar RE, Maurer HC, Crawford HC, Bednar F, et al. Combinatorial Gli activity directs immune infiltration and tumor growth in pancreatic cancer. Plos Genetics. 18: e1010315. PMID 35867772 DOI: 10.1371/journal.pgen.1010315 |
0.423 |
|
| 2022 |
Kerk S, Lin L, Myers AL, Sutton DJ, Andren A, Sajjakulnukit P, Zhang L, Zhang Y, Jiménez JA, Nelson BS, Chen B, Robinson A, Thurston G, Kemp SB, Steele NG, ... ... Crawford HC, et al. Metabolic requirement for GOT2 in pancreatic cancer depends on environmental context. Elife. 11. PMID 35815941 DOI: 10.7554/eLife.73245 |
0.31 |
|
| 2022 |
Velez-Delgado A, Donahue KL, Du W, Irizarry-Negron V, Menjivar RE, Lasse Opsahl EL, Steele NG, The S, Lazarus J, Sirihorachai VR, Yan W, Kemp SB, Kerk SA, Bollampally M, Yang S, ... ... Crawford HC, et al. Extrinsic KRAS signaling shapes the pancreatic microenvironment through fibroblast reprogramming. Cellular and Molecular Gastroenterology and Hepatology. PMID 35245687 DOI: 10.1016/j.jcmgh.2022.02.016 |
0.405 |
|
| 2022 |
Inman KS, Liu Y, Scotti Buzhardt ML, Leitges M, Krishna M, Crawford HC, Fields AP, Murray NR. Regulates Autophagy and Pancreatic Tumorigenesis in Mice. Cancers. 14. PMID 35159064 DOI: 10.3390/cancers14030796 |
0.392 |
|
| 2022 |
Cheung PF, Yang J, Fang R, Borgers A, Krengel K, Stoffel A, Althoff K, Yip CW, Siu EHL, Ng LWC, Lang KS, Cham LB, Engel DR, Soun C, Cima I, ... ... Crawford HC, et al. Progranulin mediates immune evasion of pancreatic ductal adenocarcinoma through regulation of MHCI expression. Nature Communications. 13: 156. PMID 35013174 DOI: 10.1038/s41467-021-27088-9 |
0.341 |
|
| 2021 |
Yi Z, Wei S, Jin L, Jeyarajan S, Yang J, Gu Y, Kim HS, Schechter S, Lu S, Paulsen MT, Bedi K, Narayanan IV, Ljungman M, Crawford HC, Pasca di Magliano M, et al. KDM6A Regulates Cell Plasticity and Pancreatic Cancer Progression by Non-Canonical Activin Pathway. Cellular and Molecular Gastroenterology and Hepatology. PMID 34583087 DOI: 10.1016/j.jcmgh.2021.09.014 |
0.343 |
|
| 2021 |
Kremer DM, Nelson BS, Lin L, Yarosz EL, Halbrook CJ, Kerk SA, Sajjakulnukit P, Myers A, Thurston G, Hou SW, Carpenter ES, Andren AC, Nwosu ZC, Cusmano N, Wisner S, ... ... Crawford HC, et al. GOT1 inhibition promotes pancreatic cancer cell death by ferroptosis. Nature Communications. 12: 4860. PMID 34381026 DOI: 10.1038/s41467-021-24859-2 |
0.678 |
|
| 2021 |
Kemp SB, Pasca di Magliano M, Crawford HC. Myeloid cell mediated immune suppression in pancreatic cancer. Cellular and Molecular Gastroenterology and Hepatology. PMID 34303882 DOI: 10.1016/j.jcmgh.2021.07.006 |
0.354 |
|
| 2021 |
Kemp SB, Carpenter ES, Steele NG, Donahue KL, Nwosu ZC, Pacheco A, Velez-Delgado A, Menjivar RE, Lima F, The S, Espinoza CE, Brown K, Long D, Lyssiotis CA, Rao A, ... ... Crawford HC, et al. Apolipoprotein E promotes immune suppression in pancreatic cancer through NF-kB-mediated production of CXCL1. Cancer Research. PMID 34049975 DOI: 10.1158/0008-5472.CAN-20-3929 |
0.718 |
|
| 2021 |
Kemp SB, Steele NG, Carpenter ES, Donahue KL, Bushnell GG, Morris AH, The S, Orbach SM, Sirihorachai VR, Nwosu ZC, Espinoza C, Lima F, Brown K, Girgis AA, Gunchick V, ... ... Crawford HC, et al. Pancreatic cancer is marked by complement-high blood monocytes and tumor-associated macrophages. Life Science Alliance. 4. PMID 33782087 DOI: 10.26508/lsa.202000935 |
0.703 |
|
| 2021 |
Steele NG, Biffi G, Kemp SB, Zhang Y, Drouillard D, Syu LJ, Hao Y, Oni TE, Brosnan E, Elyada E, Doshi A, Hansma C, Espinoza C, Abbas A, The S, ... ... Crawford HC, et al. Inhibition of Hedgehog signaling alters fibroblast composition in pancreatic cancer. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. PMID 33495315 DOI: 10.1158/1078-0432.CCR-20-3715 |
0.721 |
|
| 2021 |
Purohit V, Wang L, Yang H, Li J, Ney GM, Gumkowski ER, Vaidya AJ, Wang A, Bhardwaj A, Zhao E, Dolgalev I, Zamperone A, Abel EV, Magliano MPD, Crawford HC, et al. ATDC binds to KEAP1 to drive NRF2-mediated tumorigenesis and chemoresistance in pancreatic cancer. Genes & Development. PMID 33446568 DOI: 10.1101/gad.344184.120 |
0.338 |
|
| 2020 |
Steele NG, Carpenter ES, Kemp SB, Sirihorachai V, The S, Delrosario L, Lazarus J, Amir ED, Gunchick V, Espinoza C, Bell S, Harris L, Lima F, Irizarry-Negron V, Paglia D, ... ... Crawford HC, et al. Multimodal Mapping of the Tumor and Peripheral Blood Immune Landscape in Human Pancreatic Cancer. Nature Cancer. 1: 1097-1112. PMID 34296197 DOI: 10.1038/s43018-020-00121-4 |
0.694 |
|
| 2020 |
Bushnell GG, Orbach SM, Ma JA, Crawford HC, Wicha MS, Jeruss JS, Shea LD. Disease-induced immunomodulation at biomaterial scaffolds detects early pancreatic cancer in a spontaneous model. Biomaterials. 269: 120632. PMID 33418200 DOI: 10.1016/j.biomaterials.2020.120632 |
0.307 |
|
| 2020 |
Hoffman MT, Kemp SB, Salas-Escabillas DJ, Zhang Y, Steele NG, The S, Long D, Benitz S, Yan W, Margolskee RF, Bednar F, Pasca di Magliano M, Wen HJ, Crawford HC. The Gustatory Sensory G-Protein GNAT3 Suppresses Pancreatic Cancer Progression in Mice. Cellular and Molecular Gastroenterology and Hepatology. PMID 32882403 DOI: 10.1016/J.Jcmgh.2020.08.011 |
0.415 |
|
| 2020 |
Brannon A, Drouillard D, Steele N, Schoettle S, Abel EV, Crawford HC, Pasca di Magliano M. Beta 1 integrin signaling mediates pancreatic ductal adenocarcinoma resistance to MEK inhibition. Scientific Reports. 10: 11133. PMID 32636409 DOI: 10.1038/S41598-020-67814-9 |
0.472 |
|
| 2020 |
Shankar S, Tien JC, Siebenaler RF, Chugh S, Dommeti VL, Zelenka-Wang S, Wang XM, Apel IJ, Waninger J, Eyunni S, Xu A, Mody M, Goodrum A, Zhang Y, Tesmer JJ, ... ... Crawford HC, et al. An essential role for Argonaute 2 in EGFR-KRAS signaling in pancreatic cancer development. Nature Communications. 11: 2817. PMID 32499547 DOI: 10.1038/S41467-020-16309-2 |
0.431 |
|
| 2020 |
Garcia PE, Adoumie M, Kim EC, Zhang Y, Scales MK, El-Tawil YS, Shaikh AZ, Wen HJ, Bednar F, Allen BL, Wellik DM, Crawford HC, Pasca di Magliano M. Differential contribution of pancreatic fibroblast subsets to the pancreatic cancer stroma. Cellular and Molecular Gastroenterology and Hepatology. PMID 32454112 DOI: 10.1016/J.Jcmgh.2020.05.004 |
0.408 |
|
| 2020 |
Brunton H, Caligiuri G, Cunningham R, Upstill-Goddard R, Bailey UM, Garner IM, Nourse C, Dreyer S, Jones M, Moran-Jones K, Wright DW, Paulus-Hock V, Nixon C, Thomson G, Jamieson NB, ... ... Crawford HC, et al. HNF4A and GATA6 Loss Reveals Therapeutically Actionable Subtypes in Pancreatic Cancer. Cell Reports. 31: 107625. PMID 32402285 DOI: 10.1016/J.Celrep.2020.107625 |
0.378 |
|
| 2020 |
Ruggeri JM, Franco-Barraza J, Sohail A, Zhang Y, Long D, Pasca di Magliano M, Cukierman E, Fridman R, Crawford HC. Discoidin Domain Receptor 1 (DDR1) is Necessary for Tissue Homeostasis in Pancreatic Injury and Pathogenesis of Pancreatic Ductal Adenocarcinoma. The American Journal of Pathology. PMID 32339496 DOI: 10.1016/J.Ajpath.2020.03.020 |
0.442 |
|
| 2020 |
Storz P, Crawford HC. Carcinogenesis of Pancreatic Ductal Adenocarcinoma. Gastroenterology. PMID 32199881 DOI: 10.1053/J.Gastro.2020.02.059 |
0.416 |
|
| 2020 |
Crawford HC, Wallace MB, Storz P. Early detection and imaging strategies to reveal and target developing pancreatic cancer. Expert Review of Anticancer Therapy. 1-3. PMID 31986932 DOI: 10.1080/14737140.2020.1720654 |
0.343 |
|
| 2020 |
Zhang Y, Lazarus J, Steele NG, Yan W, Lee HJ, Nwosu ZC, Halbrook CJ, Menjivar RE, Kemp SB, Sirihorachai V, Velez-Delgado A, Donahue K, Carpenter ES, Brown KL, Irizarry-Negron V, ... ... Crawford HC, et al. Regulatory T cell depletion alters the tumor microenvironment and accelerates pancreatic carcinogenesis. Cancer Discovery. PMID 31911451 DOI: 10.1158/2159-8290.Cd-19-0958 |
0.751 |
|
| 2020 |
Nelson BS, Lin L, Kremer DM, Sousa CM, Cotta-Ramusino C, Myers A, Ramos J, Gao T, Kovalenko I, Wilder-Romans K, Dresser J, Davis M, Lee HJ, Nwosu ZC, Campit S, ... ... Crawford HC, et al. Tissue of origin dictates GOT1 dependence and confers synthetic lethality to radiotherapy. Cancer & Metabolism. 8: 1. PMID 31908776 DOI: 10.1186/S40170-019-0202-2 |
0.322 |
|
| 2020 |
Shankar S, Tien JC, Siebenaler RF, Chugh S, Dommeti VL, Zelenka-Wang S, Waninger J, Juckette KM, Wang X, Eyunni S, Goodrum A, Zhang Y, Apel IJ, Siddiqui J, Cao X, ... ... Crawford HC, et al. Abstract 2577: AGO2 interaction limits wild type RAS activation yet essential for disease progression in oncogenic KRAS driven cancers Immunology. 80: 2577-2577. DOI: 10.1158/1538-7445.Am2020-2577 |
0.425 |
|
| 2020 |
Carpenter E, Steele N, Kemp S, Sirihorachai V, Delrosario L, Gunchick V, Donahue K, Rao A, Anderson MA, Crawford H, Frankel T, Bednar F, Magliano MPD. Sa1422 USING ENDOSCOPIC FINE NEEDLE BIOPSIES TO MAP THE IMMUNE LANDSCAPE IN HUMAN PANCREATIC CANCER Gastrointestinal Endoscopy. 91. DOI: 10.1016/J.Gie.2020.03.1155 |
0.687 |
|
| 2019 |
Lanfranca MP, Zhang Y, Girgis A, Kasselman S, Lazarus J, Kryczek I, Delrosario L, Rhim A, Koneva L, Sartor M, Sun L, Halbrook C, Nathan H, Shi J, Crawford HC, et al. Interleukin 22 Signaling Regulates Acinar Cell Plasticity to Promote Pancreatic Tumor Development in Mice. Gastroenterology. PMID 31843590 DOI: 10.1053/J.Gastro.2019.12.010 |
0.445 |
|
| 2019 |
Bott AJ, Shen J, Tonelli C, Zhan L, Sivaram N, Jiang YP, Yu X, Bhatt V, Chiles E, Zhong H, Maimouni S, Dai W, Velasquez S, Pan JA, Muthalagu N, ... ... Crawford HC, et al. Glutamine Anabolism Plays a Critical Role in Pancreatic Cancer by Coupling Carbon and Nitrogen Metabolism. Cell Reports. 29: 1287-1298.e6. PMID 31665640 DOI: 10.1016/J.Celrep.2019.09.056 |
0.414 |
|
| 2019 |
Liu J, Gao M, Nipper M, Deng J, Sharkey FE, Johnson RL, Crawford HC, Chen Y, Wang P. Activation of the intrinsic fibroinflammatory program in adult pancreatic acinar cells triggered by Hippo signaling disruption. Plos Biology. 17: e3000418. PMID 31513574 DOI: 10.1371/Journal.Pbio.3000418 |
0.439 |
|
| 2019 |
Crawford H. Putting the Cell of Origin for Pancreatic Cancer Into its Proper Context. Cellular and Molecular Gastroenterology and Hepatology. PMID 31473247 DOI: 10.1016/J.Jcmgh.2019.08.001 |
0.431 |
|
| 2019 |
Wen HJ, Gao S, Wang Y, Ray M, Magnuson MA, Wright CVE, Di Magliano MP, Frankel TL, Crawford HC. Myeloid cell-derived HB-EGF Drives Tissue Recovery After Pancreatitis. Cellular and Molecular Gastroenterology and Hepatology. PMID 31125624 DOI: 10.1016/J.Jcmgh.2019.05.006 |
0.394 |
|
| 2019 |
Wang L, Yang H, Zamperone A, Diolaiti D, Palmbos PL, Abel EV, Purohit V, Dolgalev I, Rhim AD, Ljungman M, Hadju CH, Halbrook CJ, Bar-Sagi D, di Magliano MP, Crawford HC, et al. ATDC is required for the initiation of KRAS-induced pancreatic tumorigenesis. Genes & Development. PMID 31048544 DOI: 10.1101/Gad.323303.118 |
0.477 |
|
| 2019 |
Halbrook CJ, Pontious C, Kovalenko I, Lapienyte L, Dreyer S, Lee HJ, Thurston G, Zhang Y, Lazarus J, Sajjakulnukit P, Hong HS, Kremer DM, Nelson BS, Kemp S, Zhang L, ... ... Crawford HC, et al. Macrophage-Released Pyrimidines Inhibit Gemcitabine Therapy in Pancreatic Cancer. Cell Metabolism. PMID 30827862 DOI: 10.1016/J.Cmet.2019.02.001 |
0.423 |
|
| 2019 |
Crawford HC, di Magliano MP, Banerjee S. Signaling Networks that Control Cellular Plasticity in Pancreatic Tumorigenesis, Progression and Metastasis. Gastroenterology. PMID 30716326 DOI: 10.1053/J.Gastro.2018.12.042 |
0.458 |
|
| 2019 |
Young CC, Baker RM, Howlett CJ, Hryciw T, Herman JE, Higgs D, Gibbons R, Crawford H, Brown A, Pin CL. The Loss of ATRX Increases Susceptibility to Pancreatic Injury and Oncogenic KRAS in Female But Not Male Mice. Cellular and Molecular Gastroenterology and Hepatology. 7: 93-113. PMID 30510993 DOI: 10.1016/J.Jcmgh.2018.09.004 |
0.439 |
|
| 2019 |
Zhang Y, Lazarus J, Steele N, Lee H, Yan W, Halbrook CJ, Menjivar R, Kemp SB, Sirihoracai V, Carpenter ES, Nevison AC, Vinta A, Anderson MA, Crawford HC, Lyssiotis CA, et al. Abstract I04: Regulatory T-cell depletion causes compensatory immune suppression and accelerates pancreatic carcinogenesis Cancer Research. 79. DOI: 10.1158/1538-7445.Panca19-I04 |
0.745 |
|
| 2019 |
Thompson JK, Wu E, Alkhalili O, Crawford HC, Magliano MPd, Bednar F. Abstract C56: Bmi1 is widely expressed in acini and regulates Kras-driven transcription factor networks in early pancreatic neoplasia Robotics and Autonomous Systems. 79. DOI: 10.1158/1538-7445.Panca19-C56 |
0.439 |
|
| 2019 |
Zhang Y, Lazarus J, Steele N, Yan W, Lee H, Halbrook CJ, Menjivar R, Kemp SB, Sirihorachai V, Carpenter ES, Nevison AC, Vinta A, Anderson MA, Crawford HC, Lyssiotis CA, et al. Abstract A62: Regulatory T-cell depletion promotes oncogenic Kras-driven pancreatic carcinogenesis Cancer Research. 79. DOI: 10.1158/1538-7445.Panca19-A62 |
0.76 |
|
| 2019 |
Steele N, Kemp S, Irizarry-Negron V, Sirihorachai V, Abbas A, Carpenter E, Halbrook C, Espinoza C, Lyssiotis C, Crawford H, Frankel T, Bednar F, Allen B, Magliano MPd. Abstract A52: Modulation of Hedgehog signaling alters immune infiltration in pancreatic cancer Cancer Research. 79. DOI: 10.1158/1538-7445.Panca19-A52 |
0.761 |
|
| 2019 |
Kemp S, Steele N, Carpenter E, Sirihorachai V, Bushnell G, Morris A, Espinoza C, Lima F, Nwosu Z, Orbach S, Shea L, Bednar F, Crawford H, Magliano MPd. Abstract A25: Using biomaterial scaffolds to study the genesis of the immunosuppressive premetastatic niche in pancreatic cancer Cancer Research. 79. DOI: 10.1158/1538-7445.Panca19-A25 |
0.743 |
|
| 2019 |
Hoffman MT, Salas-Escabillas DJ, DelGiorno KE, Bednar F, Margolskee RF, Rao A, Crawford HC. Abstract A19: The role of metaplastic tuft cell chemosensory signaling in pancreatic cancer Cancer Research. 79. DOI: 10.1158/1538-7445.Panca19-A19 |
0.764 |
|
| 2019 |
Carpenter E, Steele N, Sirihorachai V, Kemp S, Delrosario L, Frankel T, Crawford H, Anderson MA, Magliano MPD. Sa1707 – Using Endoscopic Fine Needle Biopsies of Pancreatic Ductal Adenocarcinoma for Immunotherapy Precision Medicine Gastroenterology. 156: S-373. DOI: 10.1016/S0016-5085(19)37774-1 |
0.689 |
|
| 2018 |
Lazarus J, Maj T, Smith JJ, Perusina Lanfranca M, Rao A, D'Angelica MI, Delrosario L, Girgis A, Schukow C, Shia J, Kryczek I, Shi J, Wasserman I, Crawford H, Nathan H, et al. Spatial and phenotypic immune profiling of metastatic colon cancer. Jci Insight. 3. PMID 30429368 DOI: 10.1172/Jci.Insight.121932 |
0.36 |
|
| 2018 |
Zhang Y, Crawford HC, Pasca di Magliano M. Epithelial-Stromal Interactions in Pancreatic Cancer. Annual Review of Physiology. PMID 30418798 DOI: 10.1146/Annurev-Physiol-020518-114515 |
0.435 |
|
| 2018 |
D'Amico S, Shi J, Martin BL, Crawford HC, Petrenko O, Reich NC. STAT3 is a master regulator of epithelial identity and KRAS-driven tumorigenesis. Genes & Development. PMID 30135074 DOI: 10.1101/Gad.311852.118 |
0.432 |
|
| 2018 |
Abel EV, Goto M, Magnuson B, Abraham S, Ramanathan N, Hotaling E, Alaniz AA, Kumar-Sinha C, Dziubinski ML, Urs S, Wang L, Shi J, Waghray M, Ljungman M, Crawford HC, et al. HNF1A is a novel oncogene that regulates human pancreatic cancer stem cell properties. Elife. 7. PMID 30074477 DOI: 10.7554/Elife.33947 |
0.473 |
|
| 2018 |
Abel EV, Goto M, Magnuson B, Abraham S, Ramanathan N, Hotaling E, Alaniz AA, Kumar-Sinha C, Dziubinski ML, Urs S, Wang L, Shi J, Waghray M, Ljungman M, Crawford HC, et al. Author response: HNF1A is a novel oncogene that regulates human pancreatic cancer stem cell properties Elife. DOI: 10.7554/Elife.33947.042 |
0.396 |
|
| 2018 |
Gao M, Liu J, Sharkey FE, Crawford HC, Johnson RL, Chen Y, Wang P. Abstract 4087: Investigating the novel role of Hippo signaling in mouse pancreas Tumor Biology. DOI: 10.1158/1538-7445.Am2018-4087 |
0.325 |
|
| 2018 |
Hoffman MT, Crawford H. Abstract 1004: Tuft cell chemosensory signaling during pancreatic ductal adenocarcinoma Cancer Research. 78: 1004-1004. DOI: 10.1158/1538-7445.Am2018-1004 |
0.488 |
|
| 2017 |
Farrell AS, Joly MM, Allen-Petersen BL, Worth PJ, Lanciault C, Sauer D, Link J, Pelz C, Heiser LM, Morton JP, Muthalagu N, Hoffman MT, Manning SL, Pratt ED, Kendsersky ND, ... ... Crawford HC, et al. MYC regulates ductal-neuroendocrine lineage plasticity in pancreatic ductal adenocarcinoma associated with poor outcome and chemoresistance. Nature Communications. 8: 1728. PMID 29170413 DOI: 10.1038/S41467-017-01967-6 |
0.457 |
|
| 2017 |
Zhang Y, Yan W, Mathew E, Kane KT, Brannon A, Adoumie M, Vinta A, Crawford HC, Pasca di Magliano M. Epithelial-Myeloid cell crosstalk regulates acinar cell plasticity and pancreatic remodeling in mice. Elife. 6. PMID 28980940 DOI: 10.7554/Elife.27388 |
0.451 |
|
| 2017 |
Halbrook CJ, Wen HJ, Ruggeri JM, Takeuchi KK, Zhang Y, di Magliano MP, Crawford HC. Mitogen-activated Protein Kinase Kinase Activity Maintains Acinar-to-Ductal Metaplasia and Is Required for Organ Regeneration in Pancreatitis. Cellular and Molecular Gastroenterology and Hepatology. 3: 99-118. PMID 28090569 DOI: 10.1016/J.Jcmgh.2016.09.009 |
0.384 |
|
| 2017 |
Zhang Y, Yan W, Mathew E, Kane KT, Brannon A, Adoumie M, Vinta A, Crawford HC, Magliano MPd. Author response: Epithelial-Myeloid cell crosstalk regulates acinar cell plasticity and pancreatic remodeling in mice Elife. DOI: 10.7554/Elife.27388.024 |
0.399 |
|
| 2017 |
Chio IIC, Jafarnejad SM, Ponz-Sarvise M, Park Y, Rivera K, Palm W, Ohlund D, Hammell M, Crawford H, Schmidt E, Thompson C, Pappin D, Sonenberg N, Tuveson D. Abstract PR03: NRF2 promotes tumor maintenance by modulating mRNA translation in pancreatic cancer Cancer Research. 77. DOI: 10.1158/1538-7445.Transcontrol16-Pr03 |
0.463 |
|
| 2016 |
Roy N, Takeuchi KK, Ruggeri JM, Bailey P, Chang D, Li J, Leonhardt L, Puri S, Hoffman MT, Gao S, Halbrook CJ, Song Y, Ljungman M, Malik S, Wright CV, ... ... Crawford HC, et al. PDX1 dynamically regulates pancreatic ductal adenocarcinoma initiation and maintenance. Genes & Development. 30: 2669-2683. PMID 28087712 DOI: 10.1101/Gad.291021.116 |
0.464 |
|
| 2016 |
Chio II, Jafarnejad SM, Ponz-Sarvise M, Park Y, Rivera K, Palm W, Wilson J, Sangar V, Hao Y, Öhlund D, Wright K, Filippini D, Lee EJ, Da Silva B, Schoepfer C, ... ... Crawford HC, et al. NRF2 Promotes Tumor Maintenance by Modulating mRNA Translation in Pancreatic Cancer. Cell. PMID 27477511 DOI: 10.1016/J.Cell.2016.06.056 |
0.466 |
|
| 2016 |
Liou GY, Döppler H, DelGiorno KE, Zhang L, Leitges M, Crawford HC, Murphy MP, Storz P. Mutant KRas-Induced Mitochondrial Oxidative Stress in Acinar Cells Upregulates EGFR Signaling to Drive Formation of Pancreatic Precancerous Lesions. Cell Reports. PMID 26947075 DOI: 10.1016/J.Celrep.2016.02.029 |
0.734 |
|
| 2016 |
Saloman JL, Albers KM, Li D, Hartman DJ, Crawford HC, Muha EA, Rhim AD, Davis BM. Ablation of sensory neurons in a genetic model of pancreatic ductal adenocarcinoma slows initiation and progression of cancer. Proceedings of the National Academy of Sciences of the United States of America. PMID 26929329 DOI: 10.1073/Pnas.1512603113 |
0.341 |
|
| 2016 |
Hoffman MT, Gao S, Crawford H. Abstract B69: Tuft cell signaling can induce pancreatic inflammation and promote pancreatic ductal adenocarcinoma Cancer Research. 76. DOI: 10.1158/1538-7445.Panca16-B69 |
0.433 |
|
| 2016 |
Wen H, Crawford HC. Abstract A65: Initiation of pancreatic metaplasia requires ADAM17-mediated autocrine signaling, not paracrine signaling derived from macrophages Cancer Research. 76. DOI: 10.1158/1538-7445.Panca16-A65 |
0.331 |
|
| 2016 |
Wang L, Yang H, Abel EV, Palmbos PL, Halbrook C, Takeuchi K, Shi J, Zhang Y, Urs S, Waghray M, Magliano MPd, Rhim AD, Crawford HC, Simeone DM. Abstract A62: ATDC is required for KRAS-induced pancreatic tumorigenesis Cancer Research. 76. DOI: 10.1158/1538-7445.Panca16-A62 |
0.316 |
|
| 2016 |
Liou G, Doeppler H, DelGirono KE, Crawford HC, Murphy MP, Storz P. Abstract PR01: Oncogenic Kras-induced mitochondrial oxidative stress in pancreatic acini modulates the formation of precancerous lesions through autocrine EGFR signaling Metabolism-Clinical and Experimental. 76. DOI: 10.1158/1538-7445.Fbcr15-Pr01 |
0.31 |
|
| 2015 |
Huang L, Holtzinger A, Jagan I, BeGora M, Lohse I, Ngai N, Nostro C, Wang R, Muthuswamy LB, Crawford HC, Arrowsmith C, Kalloger SE, Renouf DJ, Connor AA, Cleary S, et al. Ductal pancreatic cancer modeling and drug screening using human pluripotent stem cell- and patient-derived tumor organoids. Nature Medicine. PMID 26501191 DOI: 10.1038/Nm.3973 |
0.423 |
|
| 2015 |
Qiu W, Tang SM, Lee S, Turk AT, Sireci AN, Qiu A, Rose C, Xie C, Kitajewski J, Wen HJ, Crawford HC, Sims PA, Hruban RH, Remotti HE, Su GH. Loss of Activin Receptor Type 1B Accelerates Development of Intraductal Papillary Mucinous Neoplasms in Mice With Activated KRAS. Gastroenterology. PMID 26408346 DOI: 10.1053/J.Gastro.2015.09.013 |
0.374 |
|
| 2015 |
Crawford HC. Somatostatin receptor subtype 2 as pancreatic tumorigenesis suppressor: identification of a new targetable signaling node. Gastroenterology. 148: 1279-81. PMID 25921374 DOI: 10.1053/J.Gastro.2015.04.025 |
0.322 |
|
| 2015 |
Li X, Maretzky T, Weskamp G, Monette S, Qing X, Issuree PD, Crawford HC, McIlwain DR, Mak TW, Salmon JE, Blobel CP. iRhoms 1 and 2 are essential upstream regulators of ADAM17-dependent EGFR signaling. Proceedings of the National Academy of Sciences of the United States of America. 112: 6080-5. PMID 25918388 DOI: 10.1073/Pnas.1505649112 |
0.35 |
|
| 2015 |
Liou GY, Döppler H, Braun UB, Panayiotou R, Scotti Buzhardt M, Radisky DC, Crawford HC, Fields AP, Murray NR, Wang QJ, Leitges M, Storz P. Protein kinase D1 drives pancreatic acinar cell reprogramming and progression to intraepithelial neoplasia. Nature Communications. 6: 6200. PMID 25698580 DOI: 10.1038/Ncomms7200 |
0.457 |
|
| 2015 |
Singh SK, Chen NM, Hessmann E, Siveke J, Lahmann M, Singh G, Voelker N, Vogt S, Esposito I, Schmidt A, Brendel C, Stiewe T, Gaedcke J, Mernberger M, Crawford HC, et al. Antithetical NFATc1-Sox2 and p53-miR200 signaling networks govern pancreatic cancer cell plasticity. The Embo Journal. 34: 517-30. PMID 25586376 DOI: 10.15252/Embj.201489574 |
0.46 |
|
| 2015 |
Hoffmann FS, Kuhn PH, Laurent SA, Hauck SM, Berer K, Wendlinger SA, Krumbholz M, Khademi M, Olsson T, Dreyling M, Pfister HW, Alexander T, Hiepe F, Kümpfel T, Crawford HC, et al. The immunoregulator soluble TACI is released by ADAM10 and reflects B cell activation in autoimmunity. Journal of Immunology (Baltimore, Md. : 1950). 194: 542-52. PMID 25505277 DOI: 10.4049/Jimmunol.1402070 |
0.318 |
|
| 2015 |
Takeuchi KK, Delgiorno KE, Halbrook CJ, Crawford HC. Abstract IA13: Acinar cell transdifferentiation sets the stage for early tumor heterogeneity Cancer Research. 75. DOI: 10.1158/1538-7445.Panca2014-Ia13 |
0.76 |
|
| 2015 |
Peverley LV, Halbrook CJ, Hall JC, Ardito CM, Crawford HC. Abstract A77: Investigating the role of ADAM10 in pancreatic tumor differentiation Cancer Research. 75. DOI: 10.1158/1538-7445.Panca2014-A77 |
0.511 |
|
| 2015 |
Halbrook CJ, Crawford HC. Abstract A27: Redefining the role of Notch in acinar to ductal metaplasia Cancer Research. 75. DOI: 10.1158/1538-7445.Panca2014-A27 |
0.503 |
|
| 2015 |
Takeuchi KK, Carpenter E, Wu C, Halbrook CJ, Lin RZ, Crawford HC. Abstract A04: PI3K regulation of RAC1 is required for Kras-induced pancreatic tumorigenesis Cancer Research. 75. DOI: 10.1158/1538-7445.Panca2014-A04 |
0.749 |
|
| 2015 |
Moris M, Jiang L, Zhai Q, Takeuchi KK, Crawford H, Wallace M. Su1476 Plectin-1 As a Biomarker for Malignant Progression in Intraductal Papillary Mucinous Neoplasms (IPMNs) of the Pancreas Gastroenterology. 148: S-523-S-524. DOI: 10.1016/S0016-5085(15)31747-9 |
0.301 |
|
| 2014 |
Wu CY, Carpenter ES, Takeuchi KK, Halbrook CJ, Peverley LV, Bien H, Hall JC, DelGiorno KE, Pal D, Song Y, Shi C, Lin RZ, Crawford HC. PI3K regulation of RAC1 is required for KRAS-induced pancreatic tumorigenesis in mice. Gastroenterology. 147: 1405-16.e7. PMID 25311989 DOI: 10.1053/J.Gastro.2014.08.032 |
0.794 |
|
| 2014 |
Sheshadri N, Catanzaro JM, Bott AJ, Sun Y, Ullman E, Chen EI, Pan JA, Wu S, Crawford HC, Zhang J, Zong WX. SCCA1/SERPINB3 promotes oncogenesis and epithelial-mesenchymal transition via the unfolded protein response and IL6 signaling. Cancer Research. 74: 6318-29. PMID 25213322 DOI: 10.1158/0008-5472.Can-14-0798 |
0.369 |
|
| 2014 |
Palazuelos J, Crawford HC, Klingener M, Sun B, Karelis J, Raines EW, Aguirre A. TACE/ADAM17 is essential for oligodendrocyte development and CNS myelination. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 34: 11884-96. PMID 25186737 DOI: 10.1523/Jneurosci.1220-14.2014 |
0.316 |
|
| 2014 |
Tsai YH, VanDussen KL, Sawey ET, Wade AW, Kasper C, Rakshit S, Bhatt RG, Stoeck A, Maillard I, Crawford HC, Samuelson LC, Dempsey PJ. ADAM10 regulates Notch function in intestinal stem cells of mice. Gastroenterology. 147: 822-834.e13. PMID 25038433 DOI: 10.1053/J.Gastro.2014.07.003 |
0.38 |
|
| 2014 |
Takeuchi KK, Crawford HC. Use of a preclinical model of pancreas cancer to identify potential candidates for rapalogue therapy. Gut. 63: 1379-80. PMID 24966285 DOI: 10.1136/Gutjnl-2014-307317 |
0.355 |
|
| 2014 |
Mehner C, Miller E, Khauv D, Nassar A, Oberg AL, Bamlet WR, Zhang L, Waldmann J, Radisky ES, Crawford HC, Radisky DC. Tumor cell-derived MMP3 orchestrates Rac1b and tissue alterations that promote pancreatic adenocarcinoma. Molecular Cancer Research : McR. 12: 1430-9. PMID 24850902 DOI: 10.1158/1541-7786.Mcr-13-0557-T |
0.509 |
|
| 2014 |
DelGiorno KE, Tam JW, Hall JC, Thotakura G, Crawford HC, van der Velden AW. Persistent salmonellosis causes pancreatitis in a murine model of infection. Plos One. 9: e92807. PMID 24717768 DOI: 10.1371/Journal.Pone.0092807 |
0.725 |
|
| 2014 |
Bailey JM, DelGiorno KE, Crawford HC. The secret origins and surprising fates of pancreas tumors. Carcinogenesis. 35: 1436-40. PMID 24583923 DOI: 10.1093/Carcin/Bgu056 |
0.727 |
|
| 2014 |
Delgiorno KE, Hall JC, Takeuchi KK, Pan FC, Halbrook CJ, Washington MK, Olive KP, Spence JR, Sipos B, Wright CV, Wells JM, Crawford HC. Identification and manipulation of biliary metaplasia in pancreatic tumors. Gastroenterology. 146: 233-44.e5. PMID 23999170 DOI: 10.1053/J.Gastro.2013.08.053 |
0.756 |
|
| 2014 |
Ray KC, Moss ME, Franklin JL, Weaver CJ, Higginbotham J, Song Y, Revetta FL, Blaine SA, Bridges LR, Guess KE, Coffey RJ, Crawford HC, Washington MK, Means AL. Heparin-binding epidermal growth factor-like growth factor eliminates constraints on activated Kras to promote rapid onset of pancreatic neoplasia. Oncogene. 33: 823-31. PMID 23376846 DOI: 10.1038/Onc.2013.3 |
0.46 |
|
| 2014 |
Takeuchi KK, Crawford HC. Abstract B58: EGFR and IR/IGFR activation sustains ERK1/2 and AKT signaling independently of mutant Kras in pancreatic cancer cells lines Molecular Cancer Research. 12. DOI: 10.1158/1557-3125.Rasonc14-B58 |
0.461 |
|
| 2014 |
Catanzaro J, Sheshadri N, Pan J, Sun Y, Shi C, Li J, Powers S, Crawford H, Zong W. Abstract A23: Oncogenic Ras induces inflammatory cytokine production by upregulating squamous cell carcinoma antigen (SerpinB3) Molecular Cancer Research. 12. DOI: 10.1158/1557-3125.Rasonc14-A23 |
0.332 |
|
| 2014 |
Halbrook CJ, Crawford HC. Abstract A09: Notch signaling couples with Kras or PI3K to drive EGFR independent pancreatic acinar to ductal metaplasia Molecular Cancer Research. 12. DOI: 10.1158/1557-3125.Rasonc14-A09 |
0.496 |
|
| 2013 |
Liou GY, Döppler H, Necela B, Krishna M, Crawford HC, Raimondo M, Storz P. Macrophage-secreted cytokines drive pancreatic acinar-to-ductal metaplasia through NF-κB and MMPs. The Journal of Cell Biology. 202: 563-77. PMID 23918941 DOI: 10.1083/Jcb.201301001 |
0.459 |
|
| 2013 |
Hall KC, Hill D, Otero M, Plumb DA, Froemel D, Dragomir CL, Maretzky T, Boskey A, Crawford HC, Selleri L, Goldring MB, Blobel CP. ADAM17 controls endochondral ossification by regulating terminal differentiation of chondrocytes. Molecular and Cellular Biology. 33: 3077-90. PMID 23732913 DOI: 10.1128/Mcb.00291-13 |
0.382 |
|
| 2013 |
Ali WH, Chen Q, Delgiorno KE, Su W, Hall JC, Hongu T, Tian H, Kanaho Y, Di Paolo G, Crawford HC, Frohman MA. Deficiencies of the lipid-signaling enzymes phospholipase D1 and D2 alter cytoskeletal organization, macrophage phagocytosis, and cytokine-stimulated neutrophil recruitment. Plos One. 8: e55325. PMID 23383154 DOI: 10.1371/Journal.Pone.0055325 |
0.693 |
|
| 2013 |
Guy CS, Vignali KM, Temirov J, Bettini ML, Overacre AE, Smeltzer M, Zhang H, Huppa JB, Tsai YH, Lobry C, Xie J, Dempsey PJ, Crawford HC, Aifantis I, Davis MM, et al. Distinct TCR signaling pathways drive proliferation and cytokine production in T cells. Nature Immunology. 14: 262-70. PMID 23377202 DOI: 10.1038/Ni.2538 |
0.317 |
|
| 2013 |
Hall JC, Crawford HC. Abstract 5015: Ablation of a disintegrin and metalloproteinase 10 (ADAM 10) induces significant pancreatic tumor heterogeneity and blocks cancer metastasis. Cancer Research. 73: 5015-5015. DOI: 10.1158/1538-7445.Am2013-5015 |
0.476 |
|
| 2013 |
Halbrook CJ, Takeuchi KK, Crawford HC. Abstract 3030: Regulation of EGFR in pancreatic cancer. Cancer Research. 73: 3030-3030. DOI: 10.1158/1538-7445.Am2013-3030 |
0.432 |
|
| 2013 |
DelGiorno K, Takeuchi K, Hall J, Olive K, Wells J, Crawford H. Tumor-associated pancreatic metaplasia assumes a biliary duct gland phenotype Pancreatology. 13: e22. DOI: 10.1016/J.Pan.2012.12.130 |
0.731 |
|
| 2012 |
Siveke JT, Crawford HC. KRAS above and beyond - EGFR in pancreatic cancer. Oncotarget. 3: 1262-3. PMID 23174662 DOI: 10.18632/Oncotarget.750 |
0.458 |
|
| 2012 |
Ardito CM, Grüner BM, Takeuchi KK, Lubeseder-Martellato C, Teichmann N, Mazur PK, Delgiorno KE, Carpenter ES, Halbrook CJ, Hall JC, Pal D, Briel T, Herner A, Trajkovic-Arsic M, Sipos B, ... ... Crawford HC, et al. EGF receptor is required for KRAS-induced pancreatic tumorigenesis. Cancer Cell. 22: 304-17. PMID 22975374 DOI: 10.1016/J.Ccr.2012.07.024 |
0.767 |
|
| 2012 |
Scotti ML, Smith KE, Butler AM, Calcagno SR, Crawford HC, Leitges M, Fields AP, Murray NR. Protein kinase C iota regulates pancreatic acinar-to-ductal metaplasia. Plos One. 7: e30509. PMID 22359542 DOI: 10.1371/Journal.Pone.0030509 |
0.406 |
|
| 2012 |
Hall J, Crawford H. Abstract B85: A disintegrin and metalloproteinase 10 (ADAM10) regulates pancreatic cancer progression by accelerating tumorigenesis and metastasis. Cancer Research. 72. DOI: 10.1158/1538-7445.Panca2012-B85 |
0.482 |
|
| 2012 |
Halbrook CJ, Takeuchi KK, Ardito CM, Gruener BM, Siveke JT, Crawford HC. Abstract B84: EGFR activation by the ADAM17 sheddase is required for Kras-induced pancreatic tumorigenesis. Cancer Research. 72. DOI: 10.1158/1538-7445.Panca2012-B84 |
0.8 |
|
| 2012 |
DelGiorno KE, Takeuchi K, Halbrook C, Crawford HC. Abstract B73: Tumor-associated pancreatic metaplasia assumes a biliary duct-like phenotype. Cancer Research. 72. DOI: 10.1158/1538-7445.Panca2012-B73 |
0.758 |
|
| 2012 |
Grüner B, Ardito C, Lubeseder-Martellato C, Briel T, Herner A, Mazur P, Schmid R, Crawford H, Siveke J. EGF Rezeptor signaling ist obligatorisch für die Kras-induzierte Entwicklung des Pankreaskarzinoms Zeitschrift FüR Gastroenterologie. 50. DOI: 10.1055/S-0032-1324047 |
0.744 |
|
| 2012 |
Tsai Y, Wade AW, Bhatt R, Crawford HC, Samuelson LC, Dempsey PJ. 517 Cell-Autonomous ADAM10 Signaling is Essential for Maintenance of Long-Lived Multipotent Intestinal Stem Cells Gastroenterology. 142: S-108. DOI: 10.1016/S0016-5085(12)60408-9 |
0.324 |
|
| 2011 |
Guerriero JL, Ditsworth D, Catanzaro JM, Sabino G, Furie MB, Kew RR, Crawford HC, Zong WX. DNA alkylating therapy induces tumor regression through an HMGB1-mediated activation of innate immunity. Journal of Immunology (Baltimore, Md. : 1950). 186: 3517-26. PMID 21300822 DOI: 10.4049/Jimmunol.1003267 |
0.383 |
|
| 2010 |
Mohammed A, Janakiram NB, Li Q, Madka V, Ely M, Lightfoot S, Crawford H, Steele VE, Rao CV. The epidermal growth factor receptor inhibitor gefitinib prevents the progression of pancreatic lesions to carcinoma in a conditional LSL-KrasG12D/+ transgenic mouse model. Cancer Prevention Research (Philadelphia, Pa.). 3: 1417-26. PMID 21084261 DOI: 10.1158/1940-6207.Capr-10-0038 |
0.419 |
|
| 2010 |
Bombardelli L, Carpenter ES, Wu AP, Alston N, DelGiorno KE, Crawford HC. Pancreas-specific ablation of beta1 integrin induces tissue degeneration by disrupting acinar cell polarity. Gastroenterology. 138: 2531-40, 2540.e1-4. PMID 20188101 DOI: 10.1053/J.Gastro.2010.02.043 |
0.787 |
|
| 2010 |
Song Y, Washington MK, Crawford HC. Loss of FOXA1/2 is essential for the epithelial-to-mesenchymal transition in pancreatic cancer. Cancer Research. 70: 2115-25. PMID 20160041 DOI: 10.1158/0008-5472.Can-09-2979 |
0.441 |
|
| 2010 |
Gibb DR, El Shikh M, Kang DJ, Rowe WJ, El Sayed R, Cichy J, Yagita H, Tew JG, Dempsey PJ, Crawford HC, Conrad DH. ADAM10 is essential for Notch2-dependent marginal zone B cell development and CD23 cleavage in vivo. The Journal of Experimental Medicine. 207: 623-35. PMID 20156974 DOI: 10.1084/Jem.20091990 |
0.349 |
|
| 2010 |
Tsai Y, VanDussen KL, Crawford HC, Samuelson LC, Dempsey PJ. T1728 Role of ADAM10 Signaling in Cell Proliferation and Cell Fate Specification is Conserved Between the Developing and Adult Intestine Gastroenterology. 138: S-566. DOI: 10.1016/S0016-5085(10)62606-6 |
0.326 |
|
| 2009 |
Crawford HC, Dempsey PJ, Brown G, Adam L, Moss ML. ADAM10 as a therapeutic target for cancer and inflammation. Current Pharmaceutical Design. 15: 2288-99. PMID 19601831 DOI: 10.2174/138161209788682442 |
0.363 |
|
| 2009 |
Botchkina IL, Rowehl RA, Rivadeneira DE, Karpeh MS, Crawford H, Dufour A, Ju J, Wang Y, Leyfman Y, Botchkina GI. Phenotypic subpopulations of metastatic colon cancer stem cells: genomic analysis. Cancer Genomics & Proteomics. 6: 19-29. PMID 19451087 |
0.309 |
|
| 2009 |
VanDussen KL, Stoeck A, Shang L, Crawford HC, Samuelson LC, Dempsey PJ. 277 Adam10 Is Required for Cell Lineage Specification of the Intestinal Epithelium Gastroenterology. 136: A-53-A-54. DOI: 10.1016/S0016-5085(09)60242-0 |
0.329 |
|
| 2008 |
Guerriero JL, Ditsworth D, Fan Y, Zhao F, Crawford HC, Zong WX. Chemotherapy induces tumor clearance independent of apoptosis. Cancer Research. 68: 9595-600. PMID 19047135 DOI: 10.1158/0008-5472.Can-08-2452 |
0.416 |
|
| 2008 |
McCawley LJ, Wright J, LaFleur BJ, Crawford HC, Matrisian LM. Keratinocyte expression of MMP3 enhances differentiation and prevents tumor establishment. The American Journal of Pathology. 173: 1528-39. PMID 18832569 DOI: 10.2353/Ajpath.2008.080132 |
0.617 |
|
| 2008 |
Palacios G, Crawford HC, Vaseva A, Moll UM. Mitochondrially targeted wild-type p53 induces apoptosis in a solid human tumor xenograft model. Cell Cycle (Georgetown, Tex.). 7: 2584-90. PMID 18719383 DOI: 10.4161/Cc.7.16.6070 |
0.393 |
|
| 2008 |
Ardito CM, Briggs CD, Crawford HC. Targeting of extracellular proteases required for the progression of pancreatic cancer. Expert Opinion On Therapeutic Targets. 12: 605-19. PMID 18410243 DOI: 10.1517/14728222.12.5.605 |
0.776 |
|
| 2008 |
Sawey ET, Crawford HC. Metalloproteinases and cell fate: Notch just ADAMs anymore. Cell Cycle (Georgetown, Tex.). 7: 566-9. PMID 18239463 DOI: 10.4161/Cc.7.5.5531 |
0.457 |
|
| 2007 |
Sawey ET, Johnson JA, Crawford HC. Matrix metalloproteinase 7 controls pancreatic acinar cell transdifferentiation by activating the Notch signaling pathway. Proceedings of the National Academy of Sciences of the United States of America. 104: 19327-32. PMID 18042722 DOI: 10.1073/Pnas.0705953104 |
0.437 |
|
| 2007 |
Lynch CC, Vargo-Gogola T, Martin MD, Fingleton B, Crawford HC, Matrisian LM. Matrix metalloproteinase 7 mediates mammary epithelial cell tumorigenesis through the ErbB4 receptor. Cancer Research. 67: 6760-7. PMID 17638887 DOI: 10.1158/0008-5472.Can-07-0026 |
0.778 |
|
| 2007 |
Kuhlmann KF, van Till JW, Boermeester MA, de Reuver PR, Tzvetanova ID, Offerhaus GJ, Ten Kate FJ, Busch OR, van Gulik TM, Gouma DJ, Crawford HC. Evaluation of matrix metalloproteinase 7 in plasma and pancreatic juice as a biomarker for pancreatic cancer. Cancer Epidemiology, Biomarkers & Prevention : a Publication of the American Association For Cancer Research, Cosponsored by the American Society of Preventive Oncology. 16: 886-91. PMID 17507610 DOI: 10.1158/1055-9965.Epi-06-0779 |
0.369 |
|
| 2007 |
Gorden DL, Fingleton B, Crawford HC, Jansen DE, Lepage M, Matrisian LM. Resident stromal cell-derived MMP-9 promotes the growth of colorectal metastases in the liver microenvironment. International Journal of Cancer. 121: 495-500. PMID 17417772 DOI: 10.1002/Ijc.22594 |
0.617 |
|
| 2007 |
Fingleton B, Powell WC, Crawford HC, Couchman JR, Matrisian LM. A rat monoclonal antibody that recognizes pro- and active MMP-7 indicates polarized expression in vivo. Hybridoma (2005). 26: 22-7. PMID 17316082 DOI: 10.1089/Hyb.2006.028 |
0.565 |
|
| 2005 |
Spring CM, Kelly KF, O'Kelly I, Graham M, Crawford HC, Daniel JM. The catenin p120ctn inhibits Kaiso-mediated transcriptional repression of the beta-catenin/TCF target gene matrilysin. Experimental Cell Research. 305: 253-65. PMID 15817151 DOI: 10.1016/J.Yexcr.2005.01.007 |
0.323 |
|
| 2005 |
Margulis A, Zhang W, Alt-Holland A, Crawford HC, Fusenig NE, Garlick JA. E-cadherin suppression accelerates squamous cell carcinoma progression in three-dimensional, human tissue constructs. Cancer Research. 65: 1783-91. PMID 15753375 DOI: 10.1158/0008-5472.Can-04-3399 |
0.415 |
|
| 2004 |
McCawley LJ, Crawford HC, King LE, Mudgett J, Matrisian LM. A protective role for matrix metalloproteinase-3 in squamous cell carcinoma. Cancer Research. 64: 6965-72. PMID 15466188 DOI: 10.1158/0008-5472.Can-04-0910 |
0.618 |
|
| 2004 |
Gustavson MD, Crawford HC, Fingleton B, Matrisian LM. Tcf binding sequence and position determines beta-catenin and Lef-1 responsiveness of MMP-7 promoters. Molecular Carcinogenesis. 41: 125-39. PMID 15457508 DOI: 10.1002/Mc.20049 |
0.77 |
|
| 2004 |
Lynch CC, Crawford HC, Matrisian LM, McDonnell S. Epidermal growth factor upregulates matrix metalloproteinase-7 expression through activation of PEA3 transcription factors. International Journal of Oncology. 24: 1565-72. PMID 15138601 DOI: 10.3892/Ijo.24.6.1565 |
0.607 |
|
| 2004 |
Marchenko ND, Marchenko GN, Weinreb RN, Lindsey JD, Kyshtoobayeva A, Crawford HC, Strongin AY. Beta-catenin regulates the gene of MMP-26, a novel metalloproteinase expressed both in carcinomas and normal epithelial cells. The International Journal of Biochemistry & Cell Biology. 36: 942-56. PMID 15006646 DOI: 10.1016/J.Biocel.2003.12.007 |
0.401 |
|
| 2004 |
Hingorani SR, Petricoin EF, Maitra A, Rajapakse V, King C, Jacobetz MA, Ross S, Conrads TP, Veenstra TD, Hitt BA, Kawaguchi Y, Johann D, Liotta LA, Crawford HC, Putt ME, et al. Erratum: Preinvasive and invasive ductal pancreatic cancer and its early detection in the mouse (Cancer Cell (4) (437-450)) Cancer Cell. 5. DOI: 10.1016/S1535-6108(03)00335-0 |
0.412 |
|
| 2003 |
Hingorani SR, Petricoin EF, Maitra A, Rajapakse V, King C, Jacobetz MA, Ross S, Conrads TP, Veenstra TD, Hitt BA, Kawaguchi Y, Johann D, Liotta LA, Crawford HC, Putt ME, et al. Preinvasive and invasive ductal pancreatic cancer and its early detection in the mouse. Cancer Cell. 4: 437-50. PMID 14706336 DOI: 10.1016/S1535-6108(03)00309-X |
0.468 |
|
| 2003 |
Crawford HC, Krishna US, Israel DA, Matrisian LM, Washington MK, Peek RM. Helicobacter pylori strain-selective induction of matrix metalloproteinase-7 in vitro and within gastric mucosa. Gastroenterology. 125: 1125-36. PMID 14517796 DOI: 10.1016/S0016-5085(03)01206-X |
0.563 |
|
| 2003 |
Rivat C, Le Floch N, Sabbah M, Teyrol I, Redeuilh G, Bruyneel E, Mareel M, Matrisian LM, Crawford HC, Gespach C, Attoub S. Synergistic cooperation between the AP-1 and LEF-1 transcription factors in activation of the matrilysin promoter by the src oncogene: implications in cellular invasion. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 17: 1721-3. PMID 12958188 DOI: 10.1096/Fj.03-0132Fje |
0.605 |
|
| 2003 |
Liu Y, Jiang H, Crawford HC, Hogan BL. Role for ETS domain transcription factors Pea3/Erm in mouse lung development. Developmental Biology. 261: 10-24. PMID 12941618 DOI: 10.1016/S0012-1606(03)00359-2 |
0.346 |
|
| 2002 |
Vargo-Gogola T, Crawford HC, Fingleton B, Matrisian LM. Identification of novel matrix metalloproteinase-7 (matrilysin) cleavage sites in murine and human Fas ligand. Archives of Biochemistry and Biophysics. 408: 155-61. PMID 12464266 DOI: 10.1016/S0003-9861(02)00525-8 |
0.753 |
|
| 2002 |
Vargo-Gogola T, Fingleton B, Crawford HC, Matrisian LM. Matrilysin (matrix metalloproteinase-7) selects for apoptosis-resistant mammary cells in vivo. Cancer Research. 62: 5559-63. PMID 12359768 |
0.761 |
|
| 2002 |
Crawford HC, Scoggins CR, Washington MK, Matrisian LM, Leach SD. Matrix metalloproteinase-7 is expressed by pancreatic cancer precursors and regulates acinar-to-ductal metaplasia in exocrine pancreas. The Journal of Clinical Investigation. 109: 1437-44. PMID 12045257 DOI: 10.1172/Jci15051 |
0.642 |
|
| 2002 |
Fingleton B, Vargo-Gogola T, Crawford HC, Matrisian LM. Matrilysin [MMP-7] expression selects for cells with reduced sensitivity to apoptosis. Neoplasia (New York, N.Y.). 3: 459-68. PMID 11774028 DOI: 10.1038/Sj.Neo.7900190 |
0.795 |
|
| 2001 |
Hulboy DL, Matrisian LM, Crawford HC. Loss of JunB activity enhances stromelysin 1 expression in a model of the epithelial-to-mesenchymal transition of mouse skin tumors. Molecular and Cellular Biology. 21: 5478-87. PMID 11463830 DOI: 10.1128/Mcb.21.16.5478-5487.2001 |
0.595 |
|
| 2001 |
Agnihotri R, Crawford HC, Haro H, Matrisian LM, Havrda MC, Liaw L. Osteopontin, a novel substrate for matrix metalloproteinase-3 (stromelysin-1) and matrix metalloproteinase-7 (matrilysin). The Journal of Biological Chemistry. 276: 28261-7. PMID 11375993 DOI: 10.1074/Jbc.M103608200 |
0.57 |
|
| 2001 |
Howe LR, Crawford HC, Subbaramaiah K, Hassell JA, Dannenberg AJ, Brown AM. PEA3 is up-regulated in response to Wnt1 and activates the expression of cyclooxygenase-2. The Journal of Biological Chemistry. 276: 20108-15. PMID 11274170 DOI: 10.1074/Jbc.M010692200 |
0.425 |
|
| 2001 |
Crawford HC, Fingleton B, Gustavson MD, Kurpios N, Wagenaar RA, Hassell JA, Matrisian LM. The PEA3 subfamily of Ets transcription factors synergizes with beta-catenin-LEF-1 to activate matrilysin transcription in intestinal tumors. Molecular and Cellular Biology. 21: 1370-83. PMID 11158322 DOI: 10.1128/Mcb.21.4.1370-1383.2001 |
0.799 |
|
| 2000 |
Anastasiadis PZ, Moon SY, Thoreson MA, Mariner DJ, Crawford HC, Zheng Y, Reynolds AB. Inhibition of RhoA by p120 catenin. Nature Cell Biology. 2: 637-44. PMID 10980705 DOI: 10.1038/35023588 |
0.311 |
|
| 2000 |
Fenrick R, Wang L, Nip J, Amann JM, Rooney RJ, Walker-Daniels J, Crawford HC, Hulboy DL, Kinch MS, Matrisian LM, Hiebert SW. TEL, a putative tumor suppressor, modulates cell growth and cell morphology of ras-transformed cells while repressing the transcription of stromelysin-1. Molecular and Cellular Biology. 20: 5828-39. PMID 10913166 DOI: 10.1128/Mcb.20.16.5828-5839.2000 |
0.597 |
|
| 2000 |
Haro H, Crawford HC, Fingleton B, Shinomiya K, Spengler DM, Matrisian LM. Matrix metalloproteinase-7-dependent release of tumor necrosis factor-alpha in a model of herniated disc resorption. The Journal of Clinical Investigation. 105: 143-50. PMID 10642592 DOI: 10.1172/Jci7091 |
0.544 |
|
| 2000 |
Haro H, Crawford HC, Fingleton B, MacDougall JR, Shinomiya K, Spengler DM, Matrisian LM. Matrix metalloproteinase-3-dependent generation of a macrophage chemoattractant in a model of herniated disc resorption. The Journal of Clinical Investigation. 105: 133-41. PMID 10642591 DOI: 10.1172/Jci7090 |
0.546 |
|
| 1999 |
Liaw L, Crawford HC. Functions of the extracellular matrix and matrix degrading proteases during tumor progression. Brazilian Journal of Medical and Biological Research = Revista Brasileira De Pesquisas Medicas E Biologicas. 32: 805-12. PMID 10454737 DOI: 10.1590/S0100-879X1999000700002 |
0.427 |
|
| 1999 |
Crawford HC, Fingleton BM, Rudolph-Owen LA, Goss KJ, Rubinfeld B, Polakis P, Matrisian LM. The metalloproteinase matrilysin is a target of beta-catenin transactivation in intestinal tumors. Oncogene. 18: 2883-91. PMID 10362259 DOI: 10.1038/Sj.Onc.1202627 |
0.618 |
|
| 1999 |
Fingleton BM, Heppner Goss KJ, Crawford HC, Matrisian LM. Matrilysin in early stage intestinal tumorigenesis. Apmis : Acta Pathologica, Microbiologica, Et Immunologica Scandinavica. 107: 102-10. PMID 10190286 DOI: 10.1111/J.1699-0463.1999.Tb01532.X |
0.639 |
|
| 1997 |
Dong Z, Crawford HC, Lavrovsky V, Taub D, Watts R, Matrisian LM, Colburn NH. A dominant negative mutant of jun blocking 12-O-tetradecanoylphorbol- 13-acetate-induced invasion in mouse keratinocytes Molecular Carcinogenesis. 19: 204-212. PMID 9254887 DOI: 10.1002/(Sici)1098-2744(199707)19:3<204::Aid-Mc8>3.0.Co;2-D |
0.619 |
|
| 1996 |
Crawford HC, Matrisian LM. Mechanisms controlling the transcription of matrix metalloproteinase genes in normal and neoplastic cells. Enzyme & Protein. 49: 20-37. PMID 8796995 DOI: 10.1159/000468614 |
0.566 |
|
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