☰

Leon van Haandel, Ph.D. - Publications

Affiliations: 
2010 Pharmaceutical Chemistry University of Kansas, Lawrence, KS, United States 
Area:
Pharmacy, Biochemistry
Tree Info Similar researchers PubMed Report error

11/41 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2018 Stancil SL, van Haandel L, Abdel-Rahman S, Pearce RE. Development of a UPLC-MS/MS method for quantitation of metronidazole and 2-hydroxy metronidazole in human plasma and its application to a pharmacokinetic study. Journal of Chromatography. B, Analytical Technologies in the Biomedical and Life Sciences. 1092: 272-278. PMID 29933220 DOI: 10.1016/j.jchromb.2018.06.024  0.365
2013 van Haandel L, Stobaugh JF. Folate determination in human health: UPLC-MS/MS is the emerging methodology of choice. Bioanalysis. 5: 3023-31. PMID 24320128 DOI: 10.4155/Bio.13.261  0.584
2012 van Haandel L, Becker ML, Williams TD, Stobaugh JF, Leeder JS. Comprehensive quantitative measurement of folate polyglutamates in human erythrocytes by ion pairing ultra-performance liquid chromatography/tandem mass spectrometry. Rapid Communications in Mass Spectrometry : Rcm. 26: 1617-30. PMID 22693118 DOI: 10.1002/Rcm.6268  0.593
2012 Becker ML, van Haandel L, Gaedigk R, Thomas B, Hoeltzel MF, Lasky A, Dai H, Stobaugh J, Leeder JS. Red blood cell folate concentrations and polyglutamate distribution in juvenile arthritis: predictors of folate variability. Pharmacogenetics and Genomics. 22: 236-46. PMID 22344247 DOI: 10.1097/Fpc.0B013E3283500202  0.559
2011 van Haandel L, Becker ML, Williams TD, Leeder JS, Stobaugh JF. Measurement of methotrexate polyglutamates in human erythrocytes by ion-pair UPLC-MS/MS. Bioanalysis. 3: 2783-2796. PMID 22185278 DOI: 10.4155/Bio.11.288  0.612
2011 Heemskerk AA, van Haandel L, Woods JM, McCance-Katz EF, Williams TD, Stobaugh JF, Faiman MD. LC-MS/MS method for the determination of carbamathione in human plasma. Journal of Pharmaceutical and Biomedical Analysis. 54: 799-806. PMID 21145687 DOI: 10.1016/J.Jpba.2010.10.021  0.607
2011 Becker ML, Gaedigk R, van Haandel L, Thomas B, Lasky A, Hoeltzel M, Dai H, Stobaugh J, Leeder JS. The effect of genotype on methotrexate polyglutamate variability in juvenile idiopathic arthritis and association with drug response. Arthritis and Rheumatism. 63: 276-85. PMID 20954192 DOI: 10.1002/Art.30080  0.556
2010 van Haandel L, Stobaugh JF. Bioanalytical method development for a generation 5 polyamidoamine folic acid methotrexate conjugated nanoparticle. Analytical and Bioanalytical Chemistry. 397: 1841-52. PMID 20431871 DOI: 10.1007/S00216-010-3716-6  0.56
2010 Becker ML, van Haandel L, Gaedigk R, Lasky A, Hoeltzel M, Stobaugh J, Leeder JS. Analysis of intracellular methotrexate polyglutamates in patients with juvenile idiopathic arthritis: effect of route of administration on variability in intracellular methotrexate polyglutamate concentrations. Arthritis and Rheumatism. 62: 1803-12. PMID 20191581 DOI: 10.1002/Art.27434  0.569
2009 van Haandel L, Becker ML, Leeder JS, Williams TD, Stobaugh JF. A novel high-performance liquid chromatography/mass spectrometry method for improved selective and sensitive measurement of methotrexate polyglutamation status in human red blood cells. Rapid Communications in Mass Spectrometry : Rcm. 23: 3693-702. PMID 19902549 DOI: 10.1002/Rcm.4300  0.621
2008 van Haandel L, Killmer J, Li X, Schöneich C, Stobaugh JF. Phenylisothiocyanate as a multiple chemical dimension reagent for the relative quantitation of protein nitrotyrosine Chromatographia. 68: 507-516. DOI: 10.1365/S10337-008-0761-9  0.543
Low-probability matches (unlikely to be authored by this person)
2016 van Haandel L, Gibson KT, Leeder JS, Wagner JB. Quantification of pravastatin acid, lactone and isomers in human plasma by UHPLC-MS/MS and its application to a pediatric pharmacokinetic study. Journal of Chromatography. B, Analytical Technologies in the Biomedical and Life Sciences. 1012: 169-77. PMID 26849185 DOI: 10.1016/j.jchromb.2016.01.038  0.298
2016 Van Haandel L, Gibson KT, Leeder JS, Wagner JB. Quantification of pravastatin acid, lactone and isomers in human plasma by UHPLC-MS/MS and its application to a pediatric pharmacokinetic study Journal of Chromatography B: Analytical Technologies in the Biomedical and Life Sciences. 1012: 169-177. DOI: 10.1016/j.jchromb.2016.01.038  0.298
2014 van Haandel L, Goldman JL, Pearce RE, Leeder JS. Urinary biomarkers of trimethoprim bioactivation in vivo following therapeutic dosing in children. Chemical Research in Toxicology. 27: 211-8. PMID 24380396 DOI: 10.1021/tx4003325  0.295
2019 Singh RK, van Haandel L, Kiptoo P, Becker ML, Siahaan TJ, Funk RS. Methotrexate disposition, anti-folate activity and efficacy in the collagen-induced arthritis mouse model. European Journal of Pharmacology. PMID 30951714 DOI: 10.1016/J.Ejphar.2019.03.052  0.218
2023 Losacco GL, Breitbach ZS, Walsh PL, Van Haandel L. Unified chromatography in drug development: Exploiting chaotropic/kosmotropic salts for an accelerated method development. Journal of Chromatography. A. 1709: 464392. PMID 37742458 DOI: 10.1016/j.chroma.2023.464392  0.212
2013 Funk RS, van Haandel L, Becker ML, Leeder JS. Low-dose methotrexate results in the selective accumulation of aminoimidazole carboxamide ribotide in an erythroblastoid cell line. The Journal of Pharmacology and Experimental Therapeutics. 347: 154-63. PMID 23887097 DOI: 10.1124/Jpet.113.206672  0.204
2021 Morrow R, Funk R, Becker M, Sherman A, Van Haandel L, Hudson T, Casini R, Shakhnovich V. Potential Role of Methotrexate Polyglutamates in Therapeutic Drug Monitoring for Pediatric Inflammatory Bowel Disease. Pharmaceuticals (Basel, Switzerland). 14. PMID 34069031 DOI: 10.3390/ph14050463  0.196
2022 Behrle AC, Douglas J, Leeder JS, van Haandel L. Isolation and Identification of 3,4-Seco-Solanidine-3,4-dioic acid (SSDA) as a Urinary Biomarker of Cytochrome P450 2D6 (CYP2D6) Activity. Drug Metabolism and Disposition: the Biological Fate of Chemicals. PMID 35878926 DOI: 10.1124/dmd.122.000957  0.195
2016 Dinh JC, Pearce RE, Van Haandel L, Gaedigk A, Leeder JS. Characterization of Atomoxetine Biotransformation and Implications for Development of PBPK Models for Dose Individualization in Children. Drug Metabolism and Disposition: the Biological Fate of Chemicals. PMID 27052878 DOI: 10.1124/dmd.116.069518  0.194
2014 Funk RS, van Haandel L, Leeder JS, Becker ML. Folate depletion and increased glutamation in juvenile idiopathic arthritis patients treated with methotrexate. Arthritis & Rheumatology (Hoboken, N.J.). 66: 3476-85. PMID 25186097 DOI: 10.1002/Art.38865  0.193
2016 Pramann LA, Davidow LW, van Haandel L, Funk RS. Development of Extemporaneously Compounded Aripiprazole Oral Suspensions for Use in Children. International Journal of Pharmaceutical Compounding. 20: 257-261. PMID 28333668  0.17
2012 Becker ML, van Haandel L, Talib N, Lasky A, Hoeltzel MF, Leeder JS. Intracellular folate concentrations in Down syndrome patients with arthritis Pediatric Rheumatology. 10. DOI: 10.1186/1546-0096-10-S1-A52  0.166
2019 Maulik D, van Haandel L, Allsworth J, Chaisanguanthum KS, Yeast JD, Leeder JS. The effect of race and supplementation on maternal and umbilical cord plasma folates. The Journal of Maternal-Fetal & Neonatal Medicine : the Official Journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians. 1-9. PMID 31630592 DOI: 10.1080/14767058.2019.1677597  0.152
2018 Singh RK, van Haandel L, Heruth DP, Ye SQ, Leeder JS, Becker ML, Funk RS. Nicotinamide Phosphoribosyltransferase Deficiency Potentiates the Anti-proliferative Activity of Methotrexate through Enhanced Depletion of Intracellular ATP. The Journal of Pharmacology and Experimental Therapeutics. PMID 29420256 DOI: 10.1124/Jpet.117.246199  0.148
2015 Brown JT, Abdel-Rahman SM, van Haandel L, Gaedigk A, Lin YS, Leeder JS. Single Dose, CYP2D6 Genotype-Stratified Pharmacokinetic Study of Atomoxetine in Children with ADHD. Clinical Pharmacology and Therapeutics. PMID 26660002 DOI: 10.1002/Cpt.319  0.138
2018 Wagner JB, Abdel-Rahman S, Gaedigk R, Gaedigk A, Raghuveer G, Staggs VS, Kauffman R, Van Haandel L, Steven Leeder J. Impact of genetic variation on pravastatin systemic exposure in pediatric hypercholesterolemia. Clinical Pharmacology and Therapeutics. PMID 30549267 DOI: 10.1002/cpt.1330  0.136
2020 Wagner JB, Abdel-Rahman S, Gaedigk A, Gaedigk R, Raghuveer G, Staggs VS, Van Haandel L, Steven Leeder J. Impact of SLCO1B1 genetic variation on rosuvastatin systemic exposure in pediatric hypercholesterolemia. Clinical and Translational Science. PMID 31981411 DOI: 10.1111/cts.12749  0.136
2015 Goldman JL, Leeder JS, Van Haandel L, Pearce RE. In Vitro Hepatic Oxidative Biotransformation of Trimethoprim. Drug Metabolism and Disposition: the Biological Fate of Chemicals. 43: 1372-80. PMID 26138612 DOI: 10.1124/dmd.115.065193  0.129
2018 Goldman JL, van Haandel L. Trimethoprim: The overlooked component of trimethoprim-sulfamethoxazole idiosyncratic adverse drug reactions. Pharmacoepidemiology and Drug Safety. PMID 29869446 DOI: 10.1002/pds.4574  0.113
2015 Van Haandel L, Bremmer M, Kooyman PJ, Van Veen JAR, Weber T, Hensen EJM. Structure-Activity Correlations in Hydrodesulfurization Reactions over Ni-Promoted MoxW(1-x)S2/Al2O3 Catalysts Acs Catalysis. 5: 7276-7287. DOI: 10.1021/Acscatal.5B01806  0.112
2018 Wagner JB, Abdel-Rahman S, Van Haandel L, Gaedigk A, Gaedigk R, Raghuveer G, Kauffman R, Leeder JS. Impact of SLCO1B1 Genotype on Pediatric Simvastatin Acid Pharmacokinetics. Journal of Clinical Pharmacology. PMID 29469964 DOI: 10.1002/jcph.1080  0.112
2017 Zhang LQ, Van Haandel L, Xiong M, Huang P, Heruth DP, Bi C, Gaedigk R, Jiang X, Li DY, Wyckoff G, Grigoryev DN, Gao L, Li L, Wu M, Leeder JS, et al. Metabolic and molecular insights into an essential role of nicotinamide phosphoribosyltransferase. Cell Death & Disease. 8: e2705. PMID 28333140 DOI: 10.1038/cddis.2017.132  0.105
2018 Lewis T, Van Haandel L, Scott A, Leeder JS. Intensive and prolonged urine collection in preterm infants reveals three distinct indomethacin metabolic patterns: potential implications for drug dosing. Pediatric Research. PMID 29967531 DOI: 10.1038/s41390-018-0051-7  0.103
2017 Shakhnovich V, Van Haandel L, Becker M, Funk R. O-005 Combination Therapy with Methotrexate Does Not Change Infliximab Pharmacokinetics in Children with Inflammatory Bowel Disease. Inflammatory Bowel Diseases. 23: S2. PMID 28125553 DOI: 10.1097/01.MIB.0000512515.46092.5c  0.098
2020 Funk RS, Talib NJ, Zimmerman KO, van Haandel L, Becker ML. Altered Folate Homeostasis in Children with Down Syndrome: A Potential Basis for Enhanced Methotrexate Toxicity. The Journal of Pediatrics. PMID 32111377 DOI: 10.1016/J.Jpeds.2020.01.032  0.095
2016 van Haandel L, Bremmer GM, Hensen EJM, Weber T. Influence of sulfiding agent and pressure on structure and performance of CoMo/Al2O3 hydrodesulfurization catalysts Journal of Catalysis. 342: 27-39. DOI: 10.1016/j.jcat.2016.07.009  0.086
2015 Yuan Q, Zhang D, Van Haandel L, Ye F, Xue T, Hensen EJM, Guan Y. Selective liquid phase hydrogenation of furfural to furfuryl alcohol by Ru/Zr-MOFs Journal of Molecular Catalysis a: Chemical. 406: 58-64. DOI: 10.1016/j.molcata.2015.05.015  0.071
2015 Song W, Perez Ferrandez DM, Van Haandel L, Liu P, Nijhuis TA, Hensen EJM. Selective propylene oxidation to acrolein by gold dispersed on MgCuCr2O4 spinel Acs Catalysis. 5: 1100-1111. DOI: 10.1021/cs5017062  0.058
2012 Groote R, Van Haandel L, Sijbesma RP. The effect of molecular weight and catalyst concentration on catalytic activity in mechanochemically activated transesterification using silver(I)-N-heterocyclic carbene latent catalysts Journal of Polymer Science, Part a: Polymer Chemistry. 50: 4929-4935. DOI: 10.1002/pola.26323  0.043
2018 Zhang LQ, Nsumu M, Huang P, Heruth DP, Riordan SM, Shortt K, Zhang N, Grigoryev DN, Li DY, Friesen CA, Van Haandel L, Leeder JS, Olson J, Ye SQ. Novel Protective Role of Nicotinamide Phosphoribosyltransferase in Acetaminophen-Induced Acute Liver Injury in Mice. The American Journal of Pathology. PMID 29684358 DOI: 10.1016/J.Ajpath.2018.04.004  0.037
Hide low-probability matches.