Year |
Citation |
Score |
2023 |
Yeung C, Jones-Isaac K, Lindberg K, Yang J, Bain J, Ruiz M, Koenig G, Koenig P, Countryman S, Himmelfarb J, Kelly E. Development of a Kidney Microphysiological System Hardware Platform for Microgravity Studies. Research Square. PMID 38196654 DOI: 10.21203/rs.3.rs-3750478/v1 |
0.562 |
|
2023 |
Kelly E, Lindberg K, Jones-Isaac K, Yang J, Bain J, Wang L, MacDonald J, Bammler T, Calamia J, Thummel K, Yeung C, Countryman S, Koenig P, Himmelfarb J. Impact of microgravity on a three-dimensional microphysiologic culture of the human kidney proximal tubule epithelium: cell response to serum and vitamin D. Research Square. PMID 38196580 DOI: 10.21203/rs.3.rs-3778779/v1 |
0.542 |
|
2023 |
Chang SY, Huang W, Chapron A, Quiñones AJL, Wang J, Isoherranen N, Shen DD, Kelly EJ, Himmelfarb J, Yeung CK. Incorporating Uremic Solute-mediated Inhibition of OAT1/3 Improves PBPK Prediction of Tenofovir Renal and Systemic Disposition in Patients with Severe Kidney Disease. Pharmaceutical Research. PMID 37704895 DOI: 10.1007/s11095-023-03594-x |
0.562 |
|
2022 |
Mahadeo A, Yeung CK, Himmelfarb J, Kelly EJ. Kidney microphysiological models for nephrotoxicity assessment. Current Opinion in Toxicology. 30. PMID 35495549 DOI: 10.1016/j.cotox.2022.03.002 |
0.566 |
|
2022 |
Lidberg K, Muthusamy S, Adil M, Mahadeo A, Yang J, Patel R, Wang L, Bammler T, Reichel J, Yeung C, Himmelfarb J, Kelly E, Akilesh S. Serum Protein Exposure Activates a Core Regulatory Program Driving Human Proximal Tubule Injury. Journal of the American Society of Nephrology : Jasn. PMID 35197326 DOI: 10.1681/ASN.2021060751 |
0.554 |
|
2021 |
Imaoka T, Huang W, Shum S, Hailey DW, Chang SY, Chapron A, Yeung CK, Himmelfarb J, Isoherranen N, Kelly EJ. Bridging the gap between in silico and in vivo by modeling opioid disposition in a kidney proximal tubule microphysiological system. Scientific Reports. 11: 21356. PMID 34725352 DOI: 10.1038/s41598-021-00338-y |
0.56 |
|
2021 |
Chen WY, Evangelista EA, Yang J, Kelly EJ, Yeung CK. Kidney Organoid and Microphysiological Kidney Chip Models to Accelerate Drug Development and Reduce Animal Testing. Frontiers in Pharmacology. 12: 695920. PMID 34381363 DOI: 10.3389/fphar.2021.695920 |
0.586 |
|
2021 |
Van Ness KP, Cesar F, Yeung CK, Himmelfarb J, Kelly EJ. Microphysiological Systems in ADME Sciences. Clinical and Translational Science. PMID 34378335 DOI: 10.1111/cts.13132 |
0.529 |
|
2020 |
Imaoka T, Yang J, Wang L, McDonald MG, Afsharinejad Z, Bammler TK, Van Ness K, Yeung CK, Rettie AE, Himmelfarb J, Kelly EJ. Microphysiological System Modeling of Ochratoxin A-Associated Nephrotoxicity. Toxicology. 152582. PMID 32905824 DOI: 10.1016/J.Tox.2020.152582 |
0.695 |
|
2020 |
Chapron A, Chapron BD, Hailey DW, Chang SY, Imaoka T, Thummel KE, Kelly E, Himmelfarb J, Shen D, Yeung CK. An Improved Vascularized, Dual-Channel Microphysiological System Facilitates Modeling of Proximal Tubular Solute Secretion. Acs Pharmacology & Translational Science. 3: 496-508. PMID 32566915 DOI: 10.1021/acsptsci.9b00078 |
0.575 |
|
2020 |
McDonald MG, Henderson LM, Ray S, Yeung CK, Johnson AL, Kowalski JP, Hanenberg H, Wiek C, Thummel KE, Rettie AE. Heterologous Expression and Functional Characterization of Novel CYP2C9 Variants Identified in the Alaska Native People. The Journal of Pharmacology and Experimental Therapeutics. PMID 32423989 DOI: 10.1124/Jpet.120.265850 |
0.518 |
|
2020 |
Shum S, Imaoka T, Huang W, Chang S, Yeung C, Himmelfarb J, Kelly E, Isoherranen N. Predicting renal clearance of morphine and morphine‐6‐glucuronide using the “organ‐on‐a‐chip” technology and physiologically‐based pharmacokinetic modeling The Faseb Journal. 34: 1-1. DOI: 10.1096/Fasebj.2020.34.S1.04121 |
0.576 |
|
2020 |
Imaoka T, Shum S, Chang S, Chapron A, Yeung CK, Himmelfarb J, Isoherranen N, Kelly EJ. P7 - Utilization of a microphysiological system to model renal secretion of opioids in humans Drug Metabolism and Pharmacokinetics. 35. DOI: 10.1016/J.Dmpk.2020.04.008 |
0.591 |
|
2019 |
Yeung CK, Koenig P, Countryman S, Thummel KE, Himmelfarb J, Kelly EJ. Tissue Chips in Space-Challenges and Opportunities. Clinical and Translational Science. PMID 31524321 DOI: 10.1111/Cts.12689 |
0.509 |
|
2019 |
McDonald MG, Yeung CK, Teitelbaum AM, Johnson AL, Fujii S, Kagechika H, Rettie AE. A New LC-MS Assay for the Quantitative Analysis of Vitamin K Metabolites in Human Urine. Journal of Lipid Research. PMID 30670472 DOI: 10.1194/Jlr.D087916 |
0.509 |
|
2018 |
Yeung CK, Himmelfarb J. Kidneys on Chips: Emerging Technology for Preclinical Drug Development. Clinical Journal of the American Society of Nephrology : Cjasn. PMID 30274990 DOI: 10.2215/Cjn.06690518 |
0.318 |
|
2017 |
Chang SY, Weber EJ, Sidorenko VS, Chapron A, Yeung CK, Gao C, Mao Q, Shen D, Wang J, Rosenquist TA, Dickman KG, Neumann T, Grollman AP, Kelly EJ, Himmelfarb J, et al. Human liver-kidney model elucidates the mechanisms of aristolochic acid nephrotoxicity. Jci Insight. 2. PMID 29202460 DOI: 10.1172/Jci.Insight.95978 |
0.622 |
|
2017 |
Xu M, Bhatt DK, Yeung CK, Claw KG, Chaudhry AS, Gaedigk A, Pearce RE, Broeckel U, Gaedigk R, Nickerson D, Schuetz E, Rettie AE, Leeder S, Thummel KE, Prasad B. Genetic and Non-genetic Factors Associated with Protein Abundance of Flavin-containing Monooxygenase 3 in Human Liver. The Journal of Pharmacology and Experimental Therapeutics. PMID 28819071 DOI: 10.1124/Jpet.117.243113 |
0.529 |
|
2017 |
Chapron A, Shen DD, Kestenbaum BR, Robinson-Cohen C, Himmelfarb J, Yeung CK. Does Secretory Clearance Follow Glomerular Filtration Rate in Chronic Kidney Diseases? Reconsidering the Intact Nephron Hypothesis. Clinical and Translational Science. PMID 28675584 DOI: 10.1111/Cts.12481 |
0.387 |
|
2017 |
Vernetti L, Gough A, Baetz N, Blutt S, Broughman JR, Brown JA, Foulke-Abel J, Hasan N, In J, Kelly E, Kovbasnjuk O, Repper J, Senutovitch N, Stabb J, Yeung C, et al. Corrigendum: Functional Coupling of Human Microphysiology Systems: Intestine, Liver, Kidney Proximal Tubule, Blood-Brain Barrier and Skeletal Muscle. Scientific Reports. 7: 44517. PMID 28300206 DOI: 10.1038/Srep44517 |
0.611 |
|
2017 |
Vernetti L, Gough A, Baetz N, Blutt S, Broughman JR, Brown JA, Foulke-Abel J, Hasan N, In J, Kelly E, Kovbasnjuk O, Repper J, Senutovitch N, Stabb J, Yeung C, et al. Functional Coupling of Human Microphysiology Systems: Intestine, Liver, Kidney Proximal Tubule, Blood-Brain Barrier and Skeletal Muscle. Scientific Reports. 7: 42296. PMID 28176881 DOI: 10.1038/srep42296 |
0.578 |
|
2016 |
Weber EJ, Chapron A, Chapron BD, Voellinger JL, Lidberg KA, Yeung CK, Wang Z, Yamaura Y, Hailey DW, Neumann T, Shen DD, Thummel KE, Muczynski KA, Himmelfarb J, Kelly EJ. Development of a microphysiological model of human kidney proximal tubule function. Kidney International. 90: 627-37. PMID 27521113 DOI: 10.1016/J.Kint.2016.06.011 |
0.631 |
|
2016 |
Robinson-Cohen C, Newitt R, Shen DD, Rettie AE, Kestenbaum BR, Himmelfarb J, Yeung CK. Association of FMO3 Variants and Trimethylamine N-Oxide Concentration, Disease Progression, and Mortality in CKD Patients. Plos One. 11: e0161074. PMID 27513517 DOI: 10.1371/Journal.Pone.0161074 |
0.533 |
|
2016 |
Jing J, Isoherranen N, Robinson-Cohen C, Petrie I, Kestenbaum BR, Yeung CK. Chronic Kidney Disease Alters Vitamin A Homeostasis via Effects on Hepatic RBP4 Protein Expression and Metabolic Enzymes. Clinical and Translational Science. PMID 27277845 DOI: 10.1111/Cts.12402 |
0.322 |
|
2014 |
Yeung CK, Shen DD, Thummel KE, Himmelfarb J. Effects of chronic kidney disease and uremia on hepatic drug metabolism and transport. Kidney International. 85: 522-8. PMID 24132209 DOI: 10.1038/Ki.2013.399 |
0.415 |
|
2011 |
Hachad H, Overby CL, Argon S, Yeung CK, Ragueneau-Majlessi I, Levy RH. e-PKGene: a knowledge-based research tool for analysing the impact of genetics on drug exposure. Human Genomics. 5: 506-15. PMID 21807605 DOI: 10.1186/1479-7364-5-5-506 |
0.301 |
|
2011 |
Yeung CK, Fujioka Y, Hachad H, Levy RH, Isoherranen N. Are circulating metabolites important in drug-drug interactions: Quantitative analysis of risk prediction and inhibitory potency Clinical Pharmacology and Therapeutics. 89: 105-113. PMID 21124313 DOI: 10.1038/Clpt.2010.252 |
0.324 |
|
2009 |
Isoherranen N, Hachad H, Yeung CK, Levy RH. Qualitative analysis of the role of metabolites in inhibitory drug-drug interactions: literature evaluation based on the metabolism and transport drug interaction database. Chemical Research in Toxicology. 22: 294-8. PMID 19216580 DOI: 10.1021/Tx800491E |
0.342 |
|
2009 |
Lutz JD, Dixit V, Yeung CK, Dickmann LJ, Zelter A, Thatcher JE, Nelson WL, Isoherranen N. Expression and functional characterization of cytochrome P450 26A1, a retinoic acid hydroxylase. Biochemical Pharmacology. 77: 258-68. PMID 18992717 DOI: 10.1016/J.Bcp.2008.10.012 |
0.645 |
|
2007 |
Yeung CK, Adman ET, Rettie AE. Functional characterization of genetic variants of human FMO3 associated with trimethylaminuria. Archives of Biochemistry and Biophysics. 464: 251-9. PMID 17531949 DOI: 10.1016/J.Abb.2007.04.014 |
0.542 |
|
2006 |
Yeung CK, Rettie AE. Prochiral sulfoxidation as a probe for flavin-containing monooxygenases. Methods in Molecular Biology (Clifton, N.J.). 320: 163-72. PMID 16719389 DOI: 10.1385/1-59259-998-2:163 |
0.517 |
|
2006 |
Yeung CK, Rettie AE. Benzydamine N-oxygenation as a measure of flavin-containing monooxygenase activity. Methods in Molecular Biology (Clifton, N.J.). 320: 157-62. PMID 16719388 DOI: 10.1385/1-59259-998-2:157 |
0.557 |
|
2006 |
Yeung CK, Rettie AE, Thummel KE. Polymorphisms in Cytochrome P450 and Flavin-Containing Monooxygenase Genes Gene-Environment Interactions: Fundamentals of Ecogenetics. 95-126. DOI: 10.1002/0471758043.ch7 |
0.433 |
|
2002 |
Koukouritaki SB, Simpson P, Yeung CK, Rettie AE, Hines RN. Human hepatic flavin-containing monooxygenases 1 (FMO1) and 3 (FMO3) developmental expression. Pediatric Research. 51: 236-43. PMID 11809920 DOI: 10.1203/00006450-200202000-00018 |
0.534 |
|
2001 |
Cheesman MJ, Kneller MB, Kelly EJ, Thompson SJ, Yeung CK, Eaton DL, Rettie AE. Purification and characterization of hexahistidine-tagged cyclohexanone monooxygenase expressed in Saccharomyces cerevisiae and Escherichia coli. Protein Expression and Purification. 21: 81-6. PMID 11162390 DOI: 10.1006/Prep.2000.1340 |
0.639 |
|
2000 |
Yeung CK, Lang DH, Thummel KE, Rettie AE. Immunoquantitation of FMO1 in human liver, kidney, and intestine. Drug Metabolism and Disposition: the Biological Fate of Chemicals. 28: 1107-11. PMID 10950857 |
0.565 |
|
1998 |
Lang DH, Yeung CK, Peter RM, Ibarra C, Gasser R, Itagaki K, Philpot RM, Rettie AE. Isoform specificity of trimethylamine N-oxygenation by human flavin-containing monooxygenase (FMO) and P450 enzymes: selective catalysis by FMO3. Biochemical Pharmacology. 56: 1005-12. PMID 9776311 DOI: 10.1016/S0006-2952(98)00218-4 |
0.581 |
|
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