| Year |
Citation |
Score |
| 2019 |
Waldschmidt HV, Homan KT, Cato MC, Cruz-Rodríguez O, Cannavo A, Wilson MW, Song J, Cheung JY, Koch WJ, Tesmer JJG, Larsen SD. Correction to "Structure-Based Design of Highly Selective and Potent G Protein-Coupled Receptor Kinase 2 Inhibitors Based on Paroxetine". Journal of Medicinal Chemistry. PMID 31188593 DOI: 10.1021/Acs.Jmedchem.9B00844 |
0.544 |
|
| 2017 |
Waldschmidt HV, Homan KT, Cato MC, Cruz-Rodríguez O, Cannavo A, Wilson MW, Song J, Cheung JY, Koch WJ, Tesmer JJ, Larsen SD. Structure-Based Design of Highly Selective and Potent G Protein-Coupled Receptor Kinase 2 Inhibitors Based on Paroxetine. Journal of Medicinal Chemistry. PMID 28323425 DOI: 10.1021/Acs.Jmedchem.7B00112 |
0.554 |
|
| 2016 |
Yang P, Homan KT, Li Y, Cruz-Rodriguez O, Tesmer JJ, Chen Z. Effect of Lipid Composition on Membrane Orientation of the G protein-coupled Receptor Kinase 2-Gβ1γ2 Complex. Biochemistry. PMID 27088923 DOI: 10.1021/Acs.Biochem.6B00354 |
0.378 |
|
| 2016 |
Waldschmidt HV, Homan KT, Cruz-Rodriguez O, Cato MC, Waninger-Saroni J, Larimore KM, Cannavo A, Song J, Cheung JY, Kirchhoff PD, Koch WJ, Tesmer JJ, Larsen SD. Structure-Based Design, Synthesis and Biological Evaluation of Highly Selective and Potent G Protein-Coupled Receptor Kinase 2 Inhibitors. Journal of Medicinal Chemistry. PMID 27050625 DOI: 10.1021/Acs.Jmedchem.5B02000 |
0.595 |
|
| 2015 |
Inagaki S, Ghirlando R, Vishnivetskiy SA, Homan KT, White JF, Tesmer JJ, Gurevich VV, Grisshammer R. G Protein-Coupled Receptor Kinase 2 (GRK2) and 5 (GRK5) Exhibit Selective Phosphorylation of the Neurotensin Receptor in Vitro. Biochemistry. 54: 4320-9. PMID 26120872 DOI: 10.1021/Acs.Biochem.5B00285 |
0.545 |
|
| 2015 |
Homan KT, Waldschmidt HV, Glukhova A, Cannavo A, Song J, Cheung JY, Koch WJ, Larsen SD, Tesmer JJ. Crystal Structure of G Protein-Coupled Receptor Kinase 5 in Complex with a Rationally Designed Inhibitor. The Journal of Biological Chemistry. PMID 26032411 DOI: 10.1074/Jbc.M115.647370 |
0.565 |
|
| 2015 |
Azevedo AW, Doan T, Moaven H, Sokal I, Baameur F, Vishnivetskiy SA, Homan KT, Tesmer JJ, Gurevich VV, Chen J, Rieke F. C-terminal threonines and serines play distinct roles in the desensitization of rhodopsin, a G protein-coupled receptor. Elife. 4. PMID 25910054 DOI: 10.7554/Elife.05981 |
0.456 |
|
| 2015 |
Li L, Homan KT, Vishnivetskiy SA, Manglik A, Tesmer JJ, Gurevich VV, Gurevich EV. G Protein-coupled Receptor Kinases of the GRK4 Protein Subfamily Phosphorylate Inactive G Protein-coupled Receptors (GPCRs). The Journal of Biological Chemistry. 290: 10775-90. PMID 25770216 DOI: 10.1074/Jbc.M115.644773 |
0.514 |
|
| 2015 |
Homan KT, Larimore KM, Elkins JM, Szklarz M, Knapp S, Tesmer JJ. Identification and structure-function analysis of subfamily selective g protein-coupled receptor kinase inhibitors. Acs Chemical Biology. 10: 310-9. PMID 25238254 DOI: 10.1021/Cb5006323 |
0.589 |
|
| 2015 |
Homan KT, Tesmer JJ. Molecular basis for small molecule inhibition of G protein-coupled receptor kinases. Acs Chemical Biology. 10: 246-56. PMID 24984143 DOI: 10.1021/Cb5003976 |
0.573 |
|
| 2015 |
Azevedo AW, Doan T, Moaven H, Sokal I, Baameur F, Vishnivetskiy SA, Homan KT, Tesmer JJ, Gurevich VV, Chen J, Rieke F. Author response: C-terminal threonines and serines play distinct roles in the desensitization of rhodopsin, a G protein-coupled receptor Elife. DOI: 10.7554/Elife.05981.018 |
0.374 |
|
| 2014 |
Homan KT, Wu E, Cannavo A, Koch WJ, Tesmer JJ. Identification and characterization of amlexanox as a G protein-coupled receptor kinase 5 inhibitor. Molecules (Basel, Switzerland). 19: 16937-49. PMID 25340299 DOI: 10.3390/Molecules191016937 |
0.583 |
|
| 2014 |
Homan KT, Tesmer JJ. Structural insights into G protein-coupled receptor kinase function. Current Opinion in Cell Biology. 27: 25-31. PMID 24680427 DOI: 10.1016/J.Ceb.2013.10.009 |
0.467 |
|
| 2014 |
Homan KT, Wu E, Wilson MW, Singh P, Larsen SD, Tesmer JJ. Structural and functional analysis of g protein-coupled receptor kinase inhibition by paroxetine and a rationally designed analog. Molecular Pharmacology. 85: 237-48. PMID 24220010 DOI: 10.1124/Mol.113.089631 |
0.565 |
|
| 2013 |
Vishnivetskiy SA, Ostermaier MK, Singhal A, Panneels V, Homan KT, Glukhova A, Sligar SG, Tesmer JJ, Schertler GF, Standfuss J, Gurevich VV. Constitutively active rhodopsin mutants causing night blindness are effectively phosphorylated by GRKs but differ in arrestin-1 binding. Cellular Signalling. 25: 2155-62. PMID 23872075 DOI: 10.1016/J.Cellsig.2013.07.009 |
0.436 |
|
| 2013 |
Yang P, Boughton A, Homan KT, Tesmer JJ, Chen Z. Membrane orientation of Gα(i)β(1)γ(2) and Gβ(1)γ(2) determined via combined vibrational spectroscopic studies. Journal of the American Chemical Society. 135: 5044-51. PMID 23461393 DOI: 10.1021/Ja3116026 |
0.305 |
|
| 2013 |
Homan KT, Glukhova A, Tesmer JJG. Regulation of G protein-coupled receptor kinases by phospholipids Current Medicinal Chemistry. 20: 39-46. PMID 23151001 DOI: 10.2174/09298673130105 |
0.48 |
|
| 2012 |
Thal DM, Homan KT, Chen J, Wu EK, Hinkle PM, Huang ZM, Chuprun JK, Song J, Gao E, Cheung JY, Sklar LA, Koch WJ, Tesmer JJ. Paroxetine is a direct inhibitor of g protein-coupled receptor kinase 2 and increases myocardial contractility. Acs Chemical Biology. 7: 1830-9. PMID 22882301 DOI: 10.1021/Cb3003013 |
0.563 |
|
| 2012 |
Orban T, Huang CC, Homan KT, Jastrzebska B, Tesmer JJ, Palczewski K. Substrate-induced changes in the dynamics of rhodopsin kinase (G protein-coupled receptor kinase 1). Biochemistry. 51: 3404-11. PMID 22480180 DOI: 10.1021/Bi300295Y |
0.481 |
|
| 2011 |
Balasubramaniam D, Paul LN, Homan KT, Hall MC, Stauffacher CV. Specificity of HCPTP variants toward EphA2 tyrosines by quantitative selected reaction monitoring. Protein Science : a Publication of the Protein Society. 20: 1172-81. PMID 21538645 DOI: 10.1002/Pro.646 |
0.543 |
|
| 2010 |
Homan KT, Balasubramaniam D, Zabell APR, Wiest O, Helquist P, Stauffacher CV. Identification of novel inhibitors for a low molecular weight protein tyrosine phosphatase via virtual screening Bioorganic and Medicinal Chemistry. 18: 5449-5456. PMID 20538467 DOI: 10.1016/J.Bmc.2010.04.050 |
0.63 |
|
| 2006 |
Weitgenant JA, Katsuyama I, Bigi MA, Corden SJ, Markiewicz JT, Zabell APR, Homan KT, Wiest O, Stauffacher CV, Helquist P. Synthesis of a 5-azaindole phosphonic acid as a computationally designed inhibitor of the low molecular weight phosphatase HCPTP Heterocycles. 70: 599-607. DOI: 10.3987/Com-06-S(W)38 |
0.601 |
|
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