Year |
Citation |
Score |
2004 |
Fegley D, Kathuria S, Mercier R, Li C, Goutopoulos A, Makriyannis A, Piomelli D. Anandamide transport is independent of fatty-acid amide hydrolase activity and is blocked by the hydrolysis-resistant inhibitor AM1172. Proceedings of the National Academy of Sciences of the United States of America. 101: 8756-61. PMID 15138300 DOI: 10.1073/Pnas.0400997101 |
0.442 |
|
2002 |
Goutopoulos A, Makriyannis A. From cannabis to cannabinergics: new therapeutic opportunities. Pharmacology & Therapeutics. 95: 103-17. PMID 12182958 DOI: 10.1016/S0163-7258(02)00250-4 |
0.524 |
|
2001 |
Goutopoulos A, Fan P, Khanolkar AD, Xie XQ, Lin S, Makriyannis A. Stereochemical selectivity of methanandamides for the CB1 and CB2 cannabinoid receptors and their metabolic stability. Bioorganic & Medicinal Chemistry. 9: 1673-84. PMID 11425567 DOI: 10.1016/S0968-0896(01)00088-8 |
0.538 |
|
2000 |
Lamb RJ, Järbe TU, Makriyannis A, Lin S, Goutopoulos A. Effects of Delta 9-tetrahydrocannabinol, (R)-methanandamide, SR 141716,and d-amphetamine before and during daily Delta 9-tetrahydrocannabinol dosing. European Journal of Pharmacology. 398: 251-8. PMID 10854837 DOI: 10.1016/S0014-2999(00)00318-6 |
0.456 |
|
1999 |
Gifford AN, Bruneus M, Lin S, Goutopoulos A, Makriyannis A, Volkow ND, Gatley SJ. Potentiation of the action of anandamide on hippocampal slices by the fatty acid amide hydrolase inhibitor, palmitylsulphonyl fluoride (AM 374). European Journal of Pharmacology. 383: 9-14. PMID 10556675 DOI: 10.1016/S0014-2999(99)00609-3 |
0.475 |
|
1999 |
Piomelli D, Beltramo M, Glasnapp S, Lin SY, Goutopoulos A, Xie XQ, Makriyannis A. Structural determinants for recognition and translocation by the anandamide transporter. Proceedings of the National Academy of Sciences of the United States of America. 96: 5802-7. PMID 10318965 DOI: 10.1073/pnas.96.10.5802 |
0.411 |
|
1999 |
Lang W, Qin C, Lin S, Khanolkar AD, Goutopoulos A, Fan P, Abouzid K, Meng Z, Biegel D, Makriyannis A. Substrate Specificity and Stereoselectivity of Rat Brain Microsomal Anandamide Amidohydrolase. Journal of Medicinal Chemistry. 42: 1682. PMID 10231226 DOI: 10.1021/jm990139o |
0.38 |
|
1999 |
Lang W, Qin C, Lin S, Khanolkar AD, Goutopoulos A, Fan P, Abouzid K, Meng Z, Biegel D, Makriyannis A. Substrate specificity and stereoselectivity of rat brain microsomal anandamide amidohydrolase. Journal of Medicinal Chemistry. 42: 896-902. PMID 10072686 DOI: 10.1021/Jm980461J |
0.58 |
|
1998 |
Järbe TU, Sheppard R, Lamb RJ, Makriyannis A, Lin S, Goutopoulos A. Effects of delta-9-tetrahydrocannabinol and (R)-methanandamide on open-field behavior in rats. Behavioural Pharmacology. 9: 169-74. PMID 10065936 |
0.445 |
|
1998 |
Järbe TU, Lamb RJ, Makriyannis A, Lin S, Goutopoulos A. Delta9-THC training dose as a determinant for (R)-methanandamide generalization in rats. Psychopharmacology. 140: 519-22. PMID 9888629 DOI: 10.1007/S002130050797 |
0.486 |
|
1998 |
Lin S, Khanolkar AD, Fan P, Goutopoulos A, Qin C, Papahadjis D, Makriyannis A. Novel analogues of arachidonylethanolamide (anandamide): affinities for the CB1 and CB2 cannabinoid receptors and metabolic stability. Journal of Medicinal Chemistry. 41: 5353-61. PMID 9876105 DOI: 10.1021/Jm970257G |
0.542 |
|
1998 |
Qin C, Lin S, Lang W, Goutopoulos A, Pavlopoulos S, Mauri F, Makriyannis A. Determination of anandamide amidase activity using ultraviolet-active amine derivatives and reverse-phase high-performance liquid chromatography. Analytical Biochemistry. 261: 8-15. PMID 9683506 DOI: 10.1006/Abio.1998.2713 |
0.479 |
|
1998 |
Papahatjis DP, Kourouli T, Abadji V, Goutopoulos A, Makriyannis A. Pharmacophoric requirements for cannabinoid side chains: multiple bond and C1'-substituted delta 8-tetrahydrocannabinols. Journal of Medicinal Chemistry. 41: 1195-200. PMID 9544219 DOI: 10.1021/Jm970277I |
0.473 |
|
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