| Year |
Citation |
Score |
| 2014 |
Martin EK, Pagano N, Sherlock ME, Harms K, Meggers E. Synthesis and anticancer activity of ruthenium half-sandwich complexes comprising combined metal centrochirality and planar chirality Inorganica Chimica Acta. 423: 530-539. DOI: 10.1016/J.Ica.2014.08.057 |
0.64 |
|
| 2012 |
John JK, Paraiso KH, Rebecca VW, Cantini LP, Abel EV, Pagano N, Meggers E, Mathew R, Krepler C, Izumi V, Fang B, Koomen JM, Messina JL, Herlyn M, Smalley KS. GSK3β inhibition blocks melanoma cell/host interactions by downregulating N-cadherin expression and decreasing FAK phosphorylation. The Journal of Investigative Dermatology. 132: 2818-27. PMID 22810307 DOI: 10.1038/Jid.2012.237 |
0.608 |
|
| 2011 |
Rodrik-Outmezguine VS, Chandarlapaty S, Pagano NC, Poulikakos PI, Scaltriti M, Moskatel E, Baselga J, Guichard S, Rosen N. mTOR kinase inhibition causes feedback-dependent biphasic regulation of AKT signaling. Cancer Discovery. 1: 248-59. PMID 22140653 DOI: 10.1158/2159-8290.CD-11-0085 |
0.435 |
|
| 2009 |
Pagano N, Wong EY, Breiding T, Liu H, Wilbuer A, Bregman H, Shen Q, Diamond SL, Meggers E. From imide to lactam metallo-pyridocarbazoles: distinct scaffolds for the design of selective protein kinase inhibitors. The Journal of Organic Chemistry. 74: 8997-9009. PMID 19886617 DOI: 10.1021/Jo901641K |
0.834 |
|
| 2009 |
Bullock AN, Russo S, Amos A, Pagano N, Bregman H, Debreczeni JE, Lee WH, von Delft F, Meggers E, Knapp S. Crystal structure of the PIM2 kinase in complex with an organoruthenium inhibitor. Plos One. 4: e7112. PMID 19841674 DOI: 10.1371/Journal.Pone.0007112 |
0.793 |
|
| 2009 |
Xie P, Streu C, Qin J, Bregman H, Pagano N, Meggers E, Marmorstein R. The crystal structure of BRAF in complex with an organoruthenium inhibitor reveals a mechanism for inhibition of an active form of BRAF kinase. Biochemistry. 48: 5187-98. PMID 19371126 DOI: 10.1021/Bi802067U |
0.799 |
|
| 2009 |
Anand R, Maksimoska J, Pagano N, Wong EY, Gimotty PA, Diamond SL, Meggers E, Marmorstein R. Toward the development of a potent and selective organoruthenium mammalian sterile 20 kinase inhibitor. Journal of Medicinal Chemistry. 52: 1602-11. PMID 19226137 DOI: 10.1021/Jm8005806 |
0.831 |
|
| 2009 |
Schlegel MK, Zhang L, Pagano N, Meggers E. Metal-mediated base pairing within the simplified nucleic acid GNA. Organic & Biomolecular Chemistry. 7: 476-82. PMID 19156312 DOI: 10.1039/B816142A |
0.707 |
|
| 2008 |
Atilla-Gokcumen GE, Pagano N, Streu C, Maksimoska J, Filippakopoulos P, Knapp S, Meggers E. Extremely tight binding of a ruthenium complex to glycogen synthase kinase 3. Chembiochem : a European Journal of Chemical Biology. 9: 2933-6. PMID 19035373 DOI: 10.1002/Cbic.200800489 |
0.742 |
|
| 2008 |
Atilla-Gokcumen GE, Pagano N, Streu C, Maksimoska J, Filippakopoulos P, Knapp S, Meggers E. Cover Picture: Extremely Tight Binding of a Ruthenium Complex to Glycogen Synthase Kinase 3 (ChemBioChem 18/2008) Chembiochem. 9: 2897-2897. DOI: 10.1002/Cbic.200890070 |
0.759 |
|
| 2007 |
Pagano N, Maksimoska J, Bregman H, Williams DS, Webster RD, Xue F, Meggers E. Ruthenium half-sandwich complexes as protein kinase inhibitors: derivatization of the pyridocarbazole pharmacophore ligand. Organic & Biomolecular Chemistry. 5: 1218-27. PMID 17406720 DOI: 10.1039/B700433H |
0.773 |
|
| 2007 |
Meggers E, Atilla-Gokcumen GE, Bregman H, Maksimoska J, Mulcahy SP, Pagano N, Williams DS. Exploring chemical space with organometallics: Ruthenium complexes as protein kinase inhibitors Synlett. 1177-1189. DOI: 10.1055/S-2007-973893 |
0.715 |
|
| 2006 |
Atilla-Gokcumen GE, Williams DS, Bregman H, Pagano N, Meggers E. Organometallic compounds with biological activity: a very selective and highly potent cellular inhibitor for glycogen synthase kinase 3. Chembiochem : a European Journal of Chemical Biology. 7: 1443-50. PMID 16858717 DOI: 10.1002/Cbic.200600117 |
0.772 |
|
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