Lucas Pelkmans - Publications

Affiliations: 
Institute of Molecular Systems Biology Eidgenössische Technische Hochschule Zürich, Zürich, ZH, Switzerland 

44 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2018 Berchtold D, Battich N, Pelkmans L. A Systems-Level Study Reveals Regulators of Membrane-less Organelles in Human Cells. Molecular Cell. 72: 1035-1049.e5. PMID 30503769 DOI: 10.1016/J.Molcel.2018.10.036  0.414
2018 Popovic D, Koch B, Kueblbeck M, Ellenberg J, Pelkmans L. Multivariate Control of Transcript to Protein Variability in Single Mammalian Cells. Cell Systems. 7: 398-411.e6. PMID 30342881 DOI: 10.1016/J.Cels.2018.09.001  0.33
2018 Gut G, Herrmann MD, Pelkmans L. Multiplexed protein maps link subcellular organization to cellular states. Science (New York, N.Y.). 361. PMID 30072512 DOI: 10.1126/Science.Aar7042  0.357
2018 Hock EM, Maniecka Z, Hruska-Plochan M, Reber S, Laferrière F, Sahadevan M K S, Ederle H, Gittings L, Pelkmans L, Dupuis L, Lashley T, Ruepp MD, Dormann D, Polymenidou M. Hypertonic Stress Causes Cytoplasmic Translocation of Neuronal, but Not Astrocytic, FUS due to Impaired Transportin Function. Cell Reports. 24: 987-1000.e7. PMID 30044993 DOI: 10.1016/J.Celrep.2018.06.094  0.318
2018 Rai AK, Chen JX, Selbach M, Pelkmans L. Kinase-controlled phase transition of membraneless organelles in mitosis. Nature. 559: 211-216. PMID 29973724 DOI: 10.1038/S41586-018-0279-8  0.361
2018 de Groot R, Lüthi J, Lindsay H, Holtackers R, Pelkmans L. Large-scale image-based profiling of single-cell phenotypes in arrayed CRISPR-Cas9 gene perturbation screens. Molecular Systems Biology. 14: e8064. PMID 29363560 DOI: 10.15252/Msb.20178064  0.305
2016 Green VA, Pelkmans L. A Systems Survey of Progressive Host-Cell Reorganization during Rotavirus Infection. Cell Host & Microbe. 20: 107-20. PMID 27414499 DOI: 10.1016/J.Chom.2016.06.005  0.344
2015 Battich N, Stoeger T, Pelkmans L. Control of Transcript Variability in Single Mammalian Cells. Cell. 163: 1596-610. PMID 26687353 DOI: 10.1016/J.Cell.2015.11.018  0.339
2015 Gut G, Tadmor MD, Pe'er D, Pelkmans L, Liberali P. Trajectories of cell-cycle progression from fixed cell populations. Nature Methods. 12: 951-4. PMID 26301842 DOI: 10.1038/Nmeth.3545  0.335
2015 Stoeger T, Battich N, Herrmann MD, Yakimovich Y, Pelkmans L. Computer vision for image-based transcriptomics. Methods (San Diego, Calif.). PMID 26014038 DOI: 10.1016/J.Ymeth.2015.05.016  0.331
2015 Frechin M, Stoeger T, Daetwyler S, Gehin C, Battich N, Damm EM, Stergiou L, Riezman H, Pelkmans L. Cell-intrinsic adaptation of lipid composition to local crowding drives social behaviour. Nature. PMID 26009010 DOI: 10.1038/Nature14429  0.426
2015 Scott CC, Vossio S, Vacca F, Snijder B, Larios J, Schaad O, Guex N, Kuznetsov D, Martin O, Chambon M, Turcatti G, Pelkmans L, Gruenberg J. Wnt directs the endosomal flux of LDL-derived cholesterol and lipid droplet homeostasis. Embo Reports. 16: 741-52. PMID 25851648 DOI: 10.15252/Embr.201540081  0.308
2014 Burkard C, Verheije MH, Wicht O, van Kasteren SI, van Kuppeveld FJ, Haagmans BL, Pelkmans L, Rottier PJ, Bosch BJ, de Haan CA. Coronavirus cell entry occurs through the endo-/lysosomal pathway in a proteolysis-dependent manner. Plos Pathogens. 10: e1004502. PMID 25375324 DOI: 10.1371/Journal.Ppat.1004502  0.369
2014 Liberali P, Snijder B, Pelkmans L. A hierarchical map of regulatory genetic interactions in membrane trafficking. Cell. 157: 1473-87. PMID 24906158 DOI: 10.1016/J.Cell.2014.04.029  0.387
2014 Aydin I, Weber S, Snijder B, Samperio Ventayol P, Kühbacher A, Becker M, Day PM, Schiller JT, Kann M, Pelkmans L, Helenius A, Schelhaas M. Large scale RNAi reveals the requirement of nuclear envelope breakdown for nuclear import of human papillomaviruses. Plos Pathogens. 10: e1004162. PMID 24874089 DOI: 10.1371/Journal.Ppat.1004162  0.303
2014 Franceschini A, Meier R, Casanova A, Kreibich S, Daga N, Andritschke D, Dilling S, Rämö P, Emmenlauer M, Kaufmann A, Conde-Álvarez R, Low SH, Pelkmans L, Helenius A, Hardt WD, et al. Specific inhibition of diverse pathogens in human cells by synthetic microRNA-like oligonucleotides inferred from RNAi screens. Proceedings of the National Academy of Sciences of the United States of America. 111: 4548-53. PMID 24616511 DOI: 10.1073/Pnas.1402353111  0.316
2013 Wippich F, Bodenmiller B, Trajkovska MG, Wanka S, Aebersold R, Pelkmans L. Dual specificity kinase DYRK3 couples stress granule condensation/dissolution to mTORC1 signaling. Cell. 152: 791-805. PMID 23415227 DOI: 10.1016/J.Cell.2013.01.033  0.628
2013 Stergiou L, Bauer M, Mair W, Bausch-Fluck D, Drayman N, Wollscheid B, Oppenheim A, Pelkmans L. Integrin-mediated signaling induced by simian virus 40 leads to transient uncoupling of cortical actin and the plasma membrane. Plos One. 8: e55799. PMID 23409046 DOI: 10.1371/Journal.Pone.0055799  0.4
2012 Mercer J, Snijder B, Sacher R, Burkard C, Bleck CK, Stahlberg H, Pelkmans L, Helenius A. RNAi screening reveals proteasome- and Cullin3-dependent stages in vaccinia virus infection. Cell Reports. 2: 1036-47. PMID 23084750 DOI: 10.1016/J.Celrep.2012.09.003  0.382
2012 Pelkmans L. Cell Biology. Using cell-to-cell variability--a new era in molecular biology. Science (New York, N.Y.). 336: 425-6. PMID 22539709 DOI: 10.1126/Science.1222161  0.35
2012 Snijder B, Sacher R, Rämö P, Liberali P, Mench K, Wolfrum N, Burleigh L, Scott CC, Verheije MH, Mercer J, Moese S, Heger T, Theusner K, Jurgeit A, Lamparter D, ... ... Pelkmans L, et al. Single-cell analysis of population context advances RNAi screening at multiple levels. Molecular Systems Biology. 8: 579. PMID 22531119 DOI: 10.1038/Msb.2012.9  0.366
2011 Misselwitz B, Dilling S, Vonaesch P, Sacher R, Snijder B, Schlumberger M, Rout S, Stark M, von Mering C, Pelkmans L, Hardt WD. RNAi screen of Salmonella invasion shows role of COPI in membrane targeting of cholesterol and Cdc42. Molecular Systems Biology. 7: 474. PMID 21407211 DOI: 10.1038/Msb.2011.7  0.365
2011 Snijder B, Pelkmans L. Origins of regulated cell-to-cell variability. Nature Reviews. Molecular Cell Biology. 12: 119-25. PMID 21224886 DOI: 10.1038/Nrm3044  0.342
2009 Snijder B, Sacher R, Rämö P, Damm EM, Liberali P, Pelkmans L. Population context determines cell-to-cell variability in endocytosis and virus infection. Nature. 461: 520-3. PMID 19710653 DOI: 10.1038/Nature08282  0.374
2009 Pelkmans L. Systems biology of virus infection in mammalian cells. Current Opinion in Microbiology. 12: 429-31. PMID 19631577 DOI: 10.1016/J.Mib.2009.06.017  0.388
2008 Sacher R, Stergiou L, Pelkmans L. Lessons from genetics: interpreting complex phenotypes in RNAi screens. Current Opinion in Cell Biology. 20: 483-9. PMID 18602470 DOI: 10.1016/J.Ceb.2008.06.002  0.35
2008 Liberali P, Rämö P, Pelkmans L. Protein kinases: starting a molecular systems view of endocytosis. Annual Review of Cell and Developmental Biology. 24: 501-23. PMID 18598215 DOI: 10.1146/Annurev.Cellbio.041008.145637  0.384
2008 Ghigo E, Kartenbeck J, Lien P, Pelkmans L, Capo C, Mege JL, Raoult D. Ameobal pathogen mimivirus infects macrophages through phagocytosis. Plos Pathogens. 4: e1000087. PMID 18551172 DOI: 10.1371/Journal.Ppat.1000087  0.362
2007 Schelhaas M, Malmström J, Pelkmans L, Haugstetter J, Ellgaard L, Grünewald K, Helenius A. Simian Virus 40 depends on ER protein folding and quality control factors for entry into host cells. Cell. 131: 516-29. PMID 17981119 DOI: 10.1016/J.Cell.2007.09.038  0.34
2006 Damm EM, Pelkmans L. Systems biology of virus entry in mammalian cells. Cellular Microbiology. 8: 1219-27. PMID 16803584 DOI: 10.1111/J.1462-5822.2006.00745.X  0.344
2005 Tagawa A, Mezzacasa A, Hayer A, Longatti A, Pelkmans L, Helenius A. Assembly and trafficking of caveolar domains in the cell: caveolae as stable, cargo-triggered, vesicular transporters. The Journal of Cell Biology. 170: 769-79. PMID 16129785 DOI: 10.1083/Jcb.200506103  0.356
2005 Pelkmans L. Secrets of caveolae- and lipid raft-mediated endocytosis revealed by mammalian viruses. Biochimica Et Biophysica Acta. 1746: 295-304. PMID 16126288 DOI: 10.1016/J.Bbamcr.2005.06.009  0.366
2005 Pelkmans L, Zerial M. Kinase-regulated quantal assemblies and kiss-and-run recycling of caveolae. Nature. 436: 128-33. PMID 16001074 DOI: 10.1038/Nature03866  0.414
2005 Pelkmans L. Viruses as probes for systems analysis of cellular signalling, cytoskeleton reorganization and endocytosis. Current Opinion in Microbiology. 8: 331-7. PMID 15939358 DOI: 10.1016/J.Mib.2005.02.018  0.402
2005 Pelkmans L, Fava E, Grabner H, Hannus M, Habermann B, Krausz E, Zerial M. Genome-wide analysis of human kinases in clathrin- and caveolae/raft-mediated endocytosis. Nature. 436: 78-86. PMID 15889048 DOI: 10.1038/Nature03571  0.431
2005 Damm EM, Pelkmans L, Kartenbeck J, Mezzacasa A, Kurzchalia T, Helenius A. Clathrin- and caveolin-1-independent endocytosis: entry of simian virus 40 into cells devoid of caveolae. The Journal of Cell Biology. 168: 477-88. PMID 15668298 DOI: 10.1083/Jcb.200407113  0.387
2004 Pelkmans L, Bürli T, Zerial M, Helenius A. Caveolin-stabilized membrane domains as multifunctional transport and sorting devices in endocytic membrane traffic. Cell. 118: 767-80. PMID 15369675 DOI: 10.1016/J.Cell.2004.09.003  0.349
2004 Pietiäinen V, Marjomäki V, Upla P, Pelkmans L, Helenius A, Hyypiä T. Echovirus 1 endocytosis into caveosomes requires lipid rafts, dynamin II, and signaling events. Molecular Biology of the Cell. 15: 4911-25. PMID 15356270 DOI: 10.1091/Mbc.E04-01-0070  0.378
2004 Miaczynska M, Pelkmans L, Zerial M. Not just a sink: endosomes in control of signal transduction. Current Opinion in Cell Biology. 16: 400-6. PMID 15261672 DOI: 10.1016/J.Ceb.2004.06.005  0.34
2003 Pelkmans L, Helenius A. Insider information: what viruses tell us about endocytosis. Current Opinion in Cell Biology. 15: 414-22. PMID 12892781 DOI: 10.1016/S0955-0674(03)00081-4  0.392
2002 Pelkmans L, Helenius A. Endocytosis via caveolae. Traffic (Copenhagen, Denmark). 3: 311-20. PMID 11967125 DOI: 10.1034/J.1600-0854.2002.30501.X  0.408
2002 Pelkmans L, Püntener D, Helenius A. Local actin polymerization and dynamin recruitment in SV40-induced internalization of caveolae. Science (New York, N.Y.). 296: 535-9. PMID 11964480 DOI: 10.1126/Science.1069784  0.365
2001 Pelkmans L, Kartenbeck J, Helenius A. Caveolar endocytosis of simian virus 40 reveals a new two-step vesicular-transport pathway to the ER. Nature Cell Biology. 3: 473-83. PMID 11331875 DOI: 10.1038/35074539  0.363
2000 Nagelkerken B, Van Anken E, Van Raak M, Gerez L, Mohrmann K, Van Uden N, Holthuizen J, Pelkmans L, Van Der Sluijs P. Rabaptin4, a novel effector of the small GTPase rab4a, is recruited to perinuclear recycling vesicles. The Biochemical Journal. 346: 593-601. PMID 10698684 DOI: 10.1042/0264-6021:3460593  0.321
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